Cumulative List of all Products that have received Orphan Designation (USA): Total active designations: 2002 Effecive: 5/5/2009
Generic Name :: Trade Name :: Designated Indication :: Marketing Approved Indication :: Designated Date :: Market Exculsivity Date :: Sponsor :: Address

Vaccinia Immune Globulin (Human) Intravenous :: CNJ-016 :: Treatment of complications of vaccinia vaccination :: treatment and/or modification of the following conditions, which are complications resulting from smallpox vaccination: Eczema vaccinatum Progressive vaccinia Severe generalized vaccinia Vaccinia infections in individuals who have skin conditions such as :: 18-06-2004 :: 01-05-9999 :: Cangene Corporation :: 104 Chancellor Matheson Road :: Winnipeg, ManitobaR3T 5Y3 :: CANADA

Antihemophilic factor (recombinant) :: ReFacto :: For the control and prevention of hemorrhagic episodes and for surgical prophylaxis in patients with hemophilia A (congenital factor VIII deficiency or classic hemophilia). :: 08-02-1996 :: 01-01-9999 :: Wyeth Pharmaceuticals, Inc. :: P. O. Box 8299 :: Philadelphia PA 19101-8299

Potassium Iodide Oral Solution :: ThyroShield :: For use as a thyroid blocking agent in pediatric patients exposed to radiactive iodine :: For use as a thyroid blocking agent in pediatric patients exposed to radiactive iodine :: 17-11-2004 :: 01-01-9999 :: Fleming & Company, Pharmaceuticals :: 1733 Gilsinn Lane :: Fenton MO 63026

Pulmonary surfactant replacement, porcine :: Curosurf :: For the treatment and prevention of respiratory distress syndrome in premature infants. :: Treatment (rescue) of respiratory distress syndrome in premature infants. :: 02-08-1993 :: 01-01-9999 :: Dey Laboratories :: 2751 Napa Valley Corporate Drive :: Napa CA 94558

Somatropin (rDNA origin) :: Saizen :: Treatment of idiopathic or organic growth hormone deficiency in children with growth failure. :: Long term treatment of children with growth failure due to inadequate secretion of endogenous growth hormone. :: 06-03-1987 :: 01-01-9999 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370

Somatropin (rDNA origin) :: Nutropin Depot :: Long-term treatment of children who have growth failure due to a lack of adequate endogenous growth hormone secretion. :: Long-term treatment of growth failure due to a lack of adequate endogenous growth hormone secetion for once- or twice-a-month administration. :: 28-10-1999 :: 01-01-9999 :: Genentech, Inc. :: 1 DNA Way :: South San Francisco CA 94080-4990

Somatropin (rDNA origin) injection :: Norditropin :: Treatment of growth failure in children due to inadequate growth hormone secretion. :: Long-term treatment of children who have growth failure due to inadequate secretion of endogenous growth hormone. :: 10-07-1987 :: 01-01-9999 :: Novo Nordisk Pharmaceuticals :: 100 Overlook Center :: Suite 200 :: Princeton NJ 08540

Surface active extract of saline lavage of bovine lungs :: Infasurf :: Treatment and prevention of respiratory failure due to pulmonary surfactant deficiency in preterm infants. :: Treatment and prevention of respiratory failure due to pulmonary surfactant deficiency in preterm infants. :: 07-06-1985 :: 01-01-9999 :: ONY, Inc. :: 1576 Sweet Home Road :: Amherst NY 14228

Trypan blue :: MembraneBlue :: Selectively staining epiretinal membranes during ophthalmic surgical victrectomy procedures :: For use as an aid in ophthalmic surgery by staining the epiretinal membranes during ophthalmic surgical vitrectomy procedures, facilitating removal of the tissue :: 02-08-2006 :: 20-02-2009 :: Dutch Ophthalmic Research Center Int'l BV :: Scheijdelveweg 2 :: P.O. Box 43 3214ZG Zuidland :: NETHERLANDS

Recombinant human antithrombin :: ATryn :: Treatment of congenital antithrombin deficiency to prevent the occurrence of serious, potentially life-threatening venous thromboembolisms which may develop as a result of surgical or obstetrical procedures :: Prevention of peri-operative and peri-partum thromboembolic events, in hereditary antithrombin deficient patients. :: 07-12-2007 :: 06-02-2009 :: GTC Biotherapeutics, Inc. :: 175 Crossing Blvd :: Framingham MA 01702

human fibrinogen concentrate, pasteurized :: RiaSTAP :: Treatment of fibrinogen deficient patients :: Treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency (afibrinogenemia and hypofibrinogenemia :: 13-03-2008 :: 16-01-2009 :: CSL Behring, LLC :: 1020 First Avenue :: P.O. Box 61501 :: King of Prussia PA 19406

Fludarabine phosphate oral tablets :: Treatment of B-cell chronic lymphocytic leukemia :: Treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) whose disease has not responded to or has progressed during or after treatment with at least one standard alkylating-agent containing regimen :: 18-12-2007 :: 18-12-2008 :: Antisoma :: 300 Technology Square :: Cambridge MA 02139

plerixafor :: Mozobil :: For use to improve the yield of progentor cells in the apheresis product for subsequest stem cell transplantation following myelosuppressive or myeloablative chemotherapy :: "To enhance mobilization of hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in patients with lymphoma and multiple myeloma

" :: 10-07-2003 :: 15-12-2008 :: Genzyme Corporation :: 500 Kendall Street :: Cambridge MA 02142

eltrombopag :: Promacta :: Treatment of idiopathic thrombocytopenia purpura :: Treatment of thrombocytopenia in patients with chronic immune (idiopathic) thrombocytopenic purpura who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy :: 05-05-2008 :: 20-11-2008 :: GlaxoSmithKline :: 1250 South Collegeville Road :: UP 4110 :: Collegeville PA 19426

rufinamide :: Banzel :: Treatment of Lennox-Gastaut Syndrome. :: Adjunctive therapy of seizures associated with Lennox-Gastaut syndrome. :: 08-10-2004 :: 14-11-2008 :: Eisai Medical Research, Inc. :: 55 Challenger Road :: Ridgefield NJ 07660

C1 esterase inhibitor (human) :: Cinryze :: Treatment of angioedema :: Routine prophylaxis against angioedema attacks in patients with Hereditary Angioedema (HAE) :: 16-07-2004 :: 10-10-2008 :: ViroPharma Incorporated :: 730 Stockton Drive :: Exton PA 19341

Iobenguane I 123 :: AdreView :: For the diagnosis of pheochromocytomas :: To be used in the detection of primary or metastatic pheochromocytomas or neuroblastomas as an adjunct to other diagnostic tests :: 01-12-2006 :: 19-09-2008 :: GE Healthcare, Inc. :: 101 Carnegie Center :: Princeton NJ 08540

Iobenguane I 123 :: Adreview :: For the diagnosis of neuroblastomas :: To be used in the detection of primary or metastatic pheochromocytomas or neuroblastomas as an adjunct to other diagnostic tests :: 01-12-2006 :: 19-09-2008 :: GE Healthcare, Inc. :: 101 Carnegie Center :: Princeton NJ 08540

Immune Globulin (Human) :: Gamunex :: Treatment of chronic inflammatory demyelinating polyneuropathy :: Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) to improve neuromuscular disability and impairment and for maintenance therapy to prevent relapse :: 27-07-2004 :: 12-09-2008 :: Talecris :: 8368 US 70 West :: Clayton NC 27520

romiplstim :: Nplate :: Treatment of immune thrombocytopenic purpura :: Treatment of thrombocytopenia in patients with chronic immune (idiopathic) thrombocytopenic purpura (ITP) who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy :: 27-03-2003 :: 22-08-2008 :: Amgen, Inc. :: One Amgen Center Drive :: Thousand Oaks CA 91320-1799

Tetrabenazine :: Xenazine :: Treatment of Huntington's disease :: Treatment of chorea associated with Huntington's disease :: 11-12-1997 :: 15-08-2008 :: Prestwick Pharmaceuticals, Inc :: 1825 K Street NW :: Suite 1475 :: Washington DC 20006

Sorafenib :: Nexavar :: Treatment of hepatocellular carcinoma :: Treatment of unresectable hepatocellular carcinoma :: 20-04-2006 :: 24-03-2008 :: Bayer Pharmaceuticals Corporation :: 400 Morgan Lane :: West Haven CT 06516

Bendamustine hydrochloride :: Treanda :: Treatment of chronic lymphocytic leukemia :: Treatment of patients with chronic lymphocytic leukemia :: 17-08-2007 :: 20-03-2008 :: Cephalon, Inc. :: 41 Moores Road :: Frazer PA 19355

Levoleucovorin :: For use in conjunction with high-dose methotrexate in the treatment of osteosarcoma. :: Levoleucovorin rescue is indicated after high-dose methotrexate therapy in osteosarcoma. Levoleucovorin is also indicated to diminish the toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosage of folic acid :: 01-08-1991 :: 07-03-2008 :: Spectrum Pharmaceuticals, Inc. :: 157 Technology Drive :: Irvine CA 92618

Rilonacept :: Arcalyst :: Treatment of CIAS1-Associated Periodic Syndromes :: Treatment of Cryopyrin-Assisted Periodic Syndromes (CAPS) :: 20-12-2004 :: 27-02-2008 :: Regeneron Pharmaceuticals, Inc. :: 777 Old Saw Mill River Road :: Tarrytown NY 10591

Adalimumab :: Humira :: Treatment of juvenile rheumatoid arthritis :: Treatment of Juvenile Idiopathic Arthritis :: 21-03-2005 :: 21-02-2008 :: Abbott Laboratories :: 200 Abbott Park Road :: Abbott Park IL 60064-6157

Thyrotropin alfa :: Thyrogen :: Treatment of well-differentiated papillary, follicular or combined papillary/follicular carcinomas of the thyroid :: For use as an adjunctive treatment for radioiodine ablation of thyroid tissue remnants in patients who have undergone thyroidectomy for well-differentiated thyroid cancer and who do not have evidence of metastatic thyroid cancer :: 03-08-2001 :: 14-12-2007 :: Genzyme Corporation :: One Kendall Square :: Cambridge MA 02139-1562

sapropterin :: Kuvan :: Treatment of hyperphenylalaninemia :: "Indicated to reduce blood phenylalanine (Phe) levels in patients with hyperphenylalaninemia (HPA) due to tetrahydrobiopterin- (BH4-) responsive Phenylketonuria (PKU). Kuvan is to be used in conjunction with a Phe-restricted diet.

" :: 29-01-2004 :: 13-12-2007 :: Biomarin Pharmaceutical Inc. :: 371 Bel Marin Blvd. :: Novato CA 94949

Nilotinib :: Tasigna :: Treatment of chronic myelogenous leukemia :: For the use for chronic phase (CP) and accelerated phase (AP) Philadelphia chromosome positive chronic myelogenous leukemia (CML) in adult patients resistant to or intolerant to prior therapy that included Gleevecà ®(imatinib) :: 27-04-2006 :: 29-10-2007 :: Novartis Pharmaceutical Corporation :: One Health Plaza :: East Hanover NJ 07936-1080

Raloxifene :: Evista :: Reduction of the risk of breast cancer in postmenopausal women :: Reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and reduction in risk of invasive breast cancer in postmenopausal women at high risk for invasive breast cancer :: 14-07-2005 :: 13-09-2007 :: Eli Lilly and Company :: Lilly Corporate Center :: Drop Code 1853 :: Indianapolis IN 46285

dexrazoxane :: Totect :: Treatment of anthracycline extravasation during chemotherapy :: Treatment of extravasation resulting from IV anthracycline chemotherapy :: 25-03-2004 :: 06-09-2007 :: Topo Target A/S :: Fruebjergvej 3, 2100 :: Copenhagen :: DENMARK

Lanreotide :: Somatuline Depot :: Treatment for acromegly :: Long-term treatment of acromegalic patients who have had an inadequate response to or cannot be treated with surgery and/or radiotherapy :: 11-09-2000 :: 30-08-2007 :: IPSEN, Inc. :: 27 Maple Street :: Milford MA 01757

ambrisentan :: Letairis :: Treatment of pulmonary arterial hypertension :: Treatment of pulmonary arterial hypertension (WHO group I) in patients with WHO class II or III symptoms to improve exercise capacity and delay clinical worsening :: 16-07-2004 :: 15-06-2007 :: Gilead Colorado :: 7575 West 103rd Avenue :: Suite 102 :: Westminister CO 80021-5426

Somatropin :: Norditropin :: Treatment of short stature in patients with Noonan syndrome :: Treatment of short stature in patients with Noonan syndrome :: 09-08-2006 :: 31-05-2007 :: Novo Nordisk Inc. :: 100 College Road West :: Princeton NJ 08540

Temsirolimus :: Torisel :: Treatment of renal cell carcinoma :: Treatment of advanced renal cell carcinoma :: 16-12-2004 :: 30-05-2007 :: Wyeth Pharmaceuticals, Inc. :: P. O. Box 8299 :: Phildelphia PA 19101-8299

Doxorubicin HCL liposome injection :: Doxil :: Treatment of multiple myeloma :: "For use in combination with bortezomib for the treatment of patients with multiple myeloma who have not previously received bortezomib and have at least one prior

therapy." :: 29-12-2004 :: 17-05-2007 :: Johnson & Johnson Pharmaceutical Research & Dev. :: 920 US Highway 202, P. O. Box 300 :: Raritan NJ 08869

Histrelin :: Supprelin LA :: Treatment of central precocious puberty :: Treatment of central precocious puberty :: 18-11-2005 :: 03-05-2007 :: Indevus Pharmaceuticals (Formerly Valera Pharma.) :: 33 Hayden Avenue :: Lexington MA 02421

hepatitis B immune globulin (human) :: HepaGam :: Prevention of hepatitis B recurrence following orthotopic liver transplant :: Prevention of hepatitis B recurrence following liver transplantation in HBsAG-positive liver transplant patients :: 24-03-2008 :: 06-04-2007 :: Cangene Corporation :: 155 Innovation Drive :: CANADA

Protein C concentrate :: Ceprotin :: For replacement therapy in congenital protein C deficiency for the prevention and treatment of thrombosis, pulmonary emboli, and purpura fulminans. :: Prevention and treatment of venous thrombosis and purpura fulminans :: 23-06-1992 :: 30-03-2007 :: Baxter Healthcare Corporation :: One Baxter Way :: West Lake Village CA 91362

eculizumab :: Soliris :: Treatment of paroxysmal nocturnal hemoglobinuria :: Treatment of paroxysmal nocturnal hemoglobinuria to reduce hemolysis :: 20-08-2003 :: 16-03-2007 :: Alexion Pharmaceuticals, Inc. :: 352 Knotter Drive :: Cheshire CT 06410

Antihemophilic factor (human) :: Alphanate :: Treatment of von Willebrand's disease :: For surgical and/or invasive procedures in patients with von Willebrand Disease (VWD) in whom desmopressin is either ineffective or contraindicated. It is not indicated for patients with severe VWD (Type 3) undergoing major surgery :: 05-01-1996 :: 31-01-2007 :: Grifols Biologicals Inc. :: 5555 Valley Boulevard :: Los Angeles CA 90032-3548

Balsalazide disodium :: Colazal :: Treatment of pediatric patients with ulcerative colitis :: Treatment of mildly to moderately active ulcerative colitis in patients 5 years of age and older. Safety and Effectiveness of Colazal beyond 8 weeks in children (ages 5-17) and 12 weeks in adults have not been established. :: 12-08-2005 :: 20-12-2006 :: Salix Pharmaceuticals, Inc. :: 1700 Perimeter Park Drive :: Morrisville NC 27560

Hydroxocobalamin :: Cyanokit :: Treatment of acute cyanide poisoning :: Treatment on known or suspected cyanide poisoning :: 25-11-2003 :: 15-12-2006 :: Merck Sante, s.a.a. :: 37 rue Saint Romain :: 69008 Lyon :: FRANCE

Imatinib mesylate :: Gleevec :: Treatment of systemic mastocytosis without the D816V c-kit mutation :: Treatment of adult patients with aggressive mastocytosis (ASM) without the D816V c-Kit mutation or with c-Kit mutational status unknown :: 09-09-2005 :: 19-10-2006 :: Novartis Pharmaceuticals Corporation :: One Health Plaza :: East Hanover NJ 07936-1080

Imatinib mesylate :: Gleevec :: Treatment of myeloproliferative disorders/myelodysplastic syndromes associated with platelet-derived growth factor gene re-arrangements :: Treatment of adult patients with myelodysplastic/myeloproliferative diseases (MDS/MPD) associated with PDGFR (platelet-derived growth factor receptor) gene re-arrangements :: 05-10-2005 :: 19-10-2006 :: Novartis Pharmaceuticals Corporation :: One Health Plaza :: East Hanover NJ 07936-1080

Imatinib mesylate :: Gleevec :: Treatment of idiopathic hypereosinophilic syndrome including acute and chronic eosinophilic leukemia :: Treatment of adult patients with hypereosinophic syndrome (HES) and/or chronic eosinophilic leukemia (CEL) who have the FIP1L1-PDGFRα fusion kinase (mutational analysis or FISH demonstration of CHIC2 allele deletion) and for patients with HES and/or CEL :: 25-08-2005 :: 19-10-2006 :: Novartis Pharmaceuticals Corporation :: One Health Plaza :: East Hanover NJ 07936-1080

imatinib mesylate :: Gleevec :: Treatment of Philadelphia-positive acute lymphoblastic leukemia :: Treatment of adult patients with relapsed or refractory Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ALL) :: 11-10-2005 :: 19-10-2006 :: Novartis Pharmaceuticals Corporation :: One Health Plaza :: East Hanover NJ 07936-1080

imatinib mesylate :: Gleevec :: Treatment of dermatofibrosarcoma protuberans :: Treatment of adult patients with unresectable, recurrent and/or metastatic dermatofibrosarcoma protuberans (DFSP) :: 19-12-2005 :: 19-10-2006 :: Novartis Pharmaceuticals Corporation :: One Health Plaza :: East Hanover NJ 07936-1080

Coagulation factor VIIa (recombinant) :: NovoSeven :: Prevention of bleeding episodes in patients with acquired inhibitors to Factor VIII or Factor IX :: Prevention of bleeding in surgical interventions or invasive procedures in patients with acquired hemophilia :: 21-07-2004 :: 13-10-2006 :: Novo Nordisk, Inc. :: 100 College Road West :: Princeton NJ 08540

Coagulation Factor VIIa (Recombinant) :: NovoSeven :: Treatment of bleeding episodes in patients with acquired inhibitors to Factor VIII or Factor IX :: Treatment of bleeding episodes in surgical interventions or invasive procedures in patients with acquired hemophilia :: 16-07-2004 :: 13-10-2006 :: Novo Nordisk, Inc. :: 100 College Road West :: Princeton NJ 08540

vorinostat :: Zolinza :: Treatment of T-cell non-Hodgkin's lymphoma :: Treatment of cutaneous manifestations in patients with cutaneous T-cell lymphoma (CTCL) who have progressive, persistant or recurrent disease on or following two systemic therapies. :: 16-03-2004 :: 06-10-2006 :: Merck & Co., Inc. :: P. O. Box 2000, RY 32-605 :: Rahway NJ 07065-0900

biocarbonate infusate :: Normocarb HF :: Use in the management of patients undergoing continuous renal replacement therapy with hemofiltration :: Use as a replacement solution in Continuous Renal Replacement Therapy (CRRT) to replace water and to correct electrolytes and acid-base imbalances in adults and children :: 09-08-2005 :: 26-07-2006 :: Dialysis Solutions, Inc. :: 14 Emmett Place :: Whitby, Ontario L1R 2B4 :: CANADA

idursulfase :: Elaprase :: Long term enzyme replacement therapy for patients with mucopolysaccharidosis II (Hunter Syndrome) :: Indicated for patients with Hunter syndrome (mucopolysaccharidosis II, MPS II). Idursulfase has been shown to improve walking capacity in these patients :: 28-11-2001 :: 24-07-2006 :: Shire Human Genetic Therapies, Inc. :: 700 Main Street :: Cambridge MA 02139

lenalidomide :: Revlimid :: Treatment for multiple myeloma :: For use in combination with dexamethasone for the treatment of multiple myeloma patients who have received at least one prior therapy. :: 20-09-2001 :: 29-06-2006 :: Celgene Corporation :: 86 Morris Avenue :: Summit NJ 07901

Dasatinib :: Sprycel :: Treatment of Philadelphia-positive acute lymphoblastic leukemia :: Treatment of adults with Philadelphia chromosome-positive acute lymphoblastic leukemia with resistance or intolerance to prior therapy :: 18-11-2005 :: 28-06-2006 :: Bristol-Myers Squibb Company :: 5 Research Parkway :: Wallingford CT 06492

Dasatinib :: Sprycel :: Treatment of chronic myelogenous leukemia :: Treatment of adults with chronic myeloid leukemia with resistance or intolerance to prior therapy including imatinib :: 28-11-2005 :: 28-06-2006 :: Bristol-Myers Squibb Company :: 5 Research Parkway :: Wallingford CT 06492

Thalidomide :: Thalomid :: Treatment of multiple myeloma :: Treatment of patients with newly diagnosed multiple myeloma :: 14-10-1998 :: 25-05-2006 :: Celgene Corporation :: 7 Powder Horn Dr. :: Warren NJ 07059

Infliximab :: REMICADE :: Treatment of pediatric (0 to 16 years of age) Crohn's Disease :: For reducing signs and symptoms and inducing and maintaining clinical remission in pediatric patients with moderately to severely active Crohn's disease who have had an inadequate response to conventional therapy :: 12-11-2003 :: 19-05-2006 :: Centocor, Inc. :: 200 Great Valley Parkway :: Malvern PA 19355-1307

Decitabine :: Dacogen :: Treatment of myelodysplastic syndromes. :: for treatment of patients with myelodysplastic syndromes (MDS) including previously treated and untreated, de novo and secondary MDS of all French-American-British subtypes (refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia :: 08-03-1999 :: 02-05-2006 :: Eisai Medical Research, Inc. :: 6611 Tributary Street :: Suite 200 :: Baltimore MD 21224

Recombinant human acid alpha-glucosidase :: Myozyme :: Treatment of glycogen storage disease type II. :: For use in patients with Pompe disease (GAA deficiency). Alglucosidase alfa has been shown to improve ventilator-free survival in patients with infantile onset Pompe disease as compared to an untreated historical control, whereas use of Alphaglucosidase :: 19-08-1997 :: 28-04-2006 :: Genzyme Corporation :: 500 Kendall Street :: Cambridge MA 02142

Ibuprofen lysine :: NeoProfen :: Treatment of patent ductus arteriosus. :: For closure of a clinically significant patent ductus arteriosus in premature infants weighing between 500 and 1500 g, who are no more than 32 weeks gestational age when usual medical management (e.g., fluid restriction, diuretics, respiratory support, et :: 29-10-1996 :: 13-04-2006 :: Farmacon-IL, LLC :: 1720 Post Road East :: Suite 213 :: Westport CT 06880-5643

Tacrolimus :: Prograf :: Prophylaxis of organ rejection in patients receiving heart transplants. :: Prophylaxis of organ rejection in patients receiving allogenic heart transplants. :: 06-06-2005 :: 29-03-2006 :: Astellas Pharma US, Inc. :: Three Parkway North :: Deerfield IL 60015-2548

Cetuximab :: Erbitux :: Treatment of squamous cell cancer of the head and neck in patients who express epidermal growth factor receptor. :: For use in combination with radiation therapy, for the treatment of locally or regionally advanced squamous cell carcinoma of the head and neck (SCCHN) and for use as a single agent for the treatment of patients with recurrent or metastatic SCCHN for whom :: 03-07-2000 :: 01-03-2006 :: ImClone Systems Incorporated :: 33 ImClone Drive :: Branchburg NJ 08876

lenalidomide :: Revlimid :: Treatment of myelodysplastic syndromes :: Treatment of patients with transfusion dependant anemia due to low or intermediate-1 risk myelodysplastic syndromes associated with a deletion 5 q cytogenetic abnormality with or without additional cytogenetic abnormalities :: 29-01-2004 :: 27-12-2005 :: Celgene Corporation :: 86 Morris Avenue :: Summit NJ 07901

Sorafenib :: Nexavar :: Treatment of renal cell carcinoma. :: Treatment of patients with advanced renal cell carcinoma :: 08-10-2004 :: 20-12-2005 :: Bayer Pharmaceutical Corporation :: 400 Morgan Lane :: West Haven CT 06516

mecasermin rinfabate :: iPLEX :: Treatment of growth hormone insensitivity syndrome (GHIS) :: Treatment of growth failure in children with severe primary IGF-1 deficiency (Primary IGFD) or with growth hormone (GH) gene deletion who have developed neutralizing antibodies to growth hormone :: 17-05-2002 :: 12-12-2005 :: Insmed, Inc. :: 8720 Stony Point Parkway :: Suite 200 :: Richmond VA 23235

oxybate :: Xyrem :: Treatment of narcolepsy :: Treatment of excessive daytime sleepiness in patients with narcolepsy :: 07-11-1994 :: 18-11-2005 :: Jazz Pharmaceuticals :: 3180 Porter Drive :: Palo Alto CA 94304

Deferasirox :: Exjade :: Treatment of chronic iron overload in patients with transfusion-dependent anemias :: Treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients 2 years of age or older :: 21-11-2002 :: 02-11-2005 :: Novartis Pharmaceuticals Corporation :: 59 Route 10 :: East Hanover NJ 07936-1080

nelarabine :: Arranon :: Treatment of acute lymphoblastic leukemia and lymphoblastic lymphoma :: Treatment of patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma whose disease has not responded to or has relapsed following treatment with at least two chemotherapy regimens :: 10-08-2004 :: 28-10-2005 :: GlaxoSmithKline :: One Franklin Plaza :: Phildelphia PA 19101

Mecasermin :: Increlex :: Treatment of growth hormone insensitivity syndrome. :: Long-term treatment of growth failure in children with severe primary IGF-1 deficiency (Primary IGFD) or with growth hormone (GH) gene deletion who have developed neutralizing antibodies to growth hormone. :: 12-12-1995 :: 30-08-2005 :: Tercica, Inc. :: 2000 Sierra Point Parkway :: Suite 400 :: Brisbane CA 94005

Coagulation factor VIIa (recombinant) :: NovoSeven :: Prevention of bleeding episodes in patients with hemophilia A or B, with or without inhibitors :: Prevention of bleeding in surgical interventions or invasive procedures in hemophilia A or B patients with inhibitors to Factor VIII or Factor IX :: 18-06-2004 :: 12-08-2005 :: Novo Nordisk, Inc. :: 100 College Road West :: Princeton NJ 08540

quinine Sulfate :: Treatment of malaria :: Treatment of uncomplicated Plasmodium falciparum malaria :: 03-06-2004 :: 12-08-2005 :: AR Holding Company, Inc. :: 1100 Orthodox Street :: Philadelphia PA 19124

meloxicam :: Mobic :: Treatment of juvenile rheumatoid arthritis :: For relief of the signs and symptoms of pauciarticular or polyarticular course Juvenile Rheumatoid Arthritis in patients 2 years of age or older :: 22-11-2002 :: 11-08-2005 :: Boehringer Ingelheim Pharmaceuticals, Inc. :: 900 Ridgebury Road :: P. O. Box 368 :: Ridgefield CT 06877-0368

Coagulation factor VIIa (recombinant) :: NovoSeven :: "Prevention of bleeding episodes in patients with congenital Factor VII

deficiency

" :: Prevention of bleeding in surgical interventions or invasive procedures in patients with congenital F VII deficiency :: 10-09-2004 :: 11-07-2005 :: Novo Nordisk, Inc. :: 100 College Road West :: Princeton NJ 08540

Coagulation factor VIIa (recombinant) :: NovoSeven :: Treatment of bleeding episodes in patients with congenital factor VII deficiency :: Treatment of bleeding episodes in patients with Factor VII Deficiency :: 10-09-2004 :: 11-07-2005 :: Novo Nordisk, Inc. :: 100 College Road West :: Princeton NJ 08540

N-acetylgalactosamine-4-sulfatase, recombinant human :: Naglazyme :: Treatment of mucopolysaccharidosis Type VI (Maroteaux-Lamy syndrome). :: For patients with mucopolysaccharidosis VI. Galsulfase has been shown to improve walking and stair-climbing capacity. :: 17-02-1999 :: 31-05-2005 :: BioMarin Pharmaceutical, Inc. :: 105 Digital Drive :: Novato CA 94949-5608

Fluocinolone :: Retisert :: Treatment uveitis involving the posterior segment of the eye. :: Treatment of chronic non-infectious uveitis affecting the posterior segment of the eye :: 31-07-2000 :: 08-04-2005 :: Bausch & Lomb Pharmaceuticals, Inc. :: 8500 Hidden River Parkway :: Tampa FL 33637

Bortezomib :: Velcade :: Treatment of multiple myeloma :: Treatment of multiple myeloma patients who have received at least one prior therapy :: 15-01-2003 :: 25-03-2005 :: Millennium Pharmaceuticals, Inc. :: 40 Landsdowne Street :: Canbridge MA 02139

temozolomide :: Temodar :: Treatment of malignant glioma :: Treatment of adult patients with newly diagnosed glioblastoma multiforme concomitatly with radiotherapy and then as maintenance treatment :: 05-10-1998 :: 15-03-2005 :: Schering-Plough Reasearch Institute :: 2000 Galloping Hill Rd. :: Kenilworth NJ 07033

Vaccinia Immune Globulin (Human) Intravenous :: Treatment of severe complications from the smallpox vaccine :: Treatment and modification of aberrant infections induced by vaccinia virus that include its accidental implantation in eyes (except in cases of isolated keratitis), mouth, or other areas where vaccinia infection would constitute a special hazard; eczema :: 18-06-2004 :: 18-02-2005 :: DynPort Vaccine Company LLC :: 64 Thomas Johnson Drive :: Frederick MD 21702

benzoate/phenylacetate :: Ammonul :: Treatment of acute hyperammonemia and associated encephalopathy in patients with deficiencies in enzymes of the urea cycle. :: "Adjunctive therapy in the treatment of acute hyperammonemia and associated encephalopathy in patients with deficiencies in enzymes of the urea cycle.

" :: 22-11-1993 :: 17-02-2005 :: Medicis Pharmaceutical Corp. :: 8125 N. Hayden Road :: Scottsdale AZ 85258

Iloprost inhalation solution :: Ventavis :: Treatment of pulmonary arterial hypertension :: Treatment of pulmonary arterial hypertension (WHO Group I) in patients with NYHA Class III or IV symptoms :: 17-08-2004 :: 29-12-2004 :: CoTherix, Inc. :: 5000 Shoreline Court :: South San Francisco CA 94080

clofarabine :: Clolar :: Treatment of acute lymphoblastic leukemia :: Treatment of pediatric patients 1 to 21 years old with relapsed or refractory acute lymphoblastic leukemia after at least two prior regimens :: 07-02-2002 :: 28-12-2004 :: Genzyme Corporation :: 4545 Horizon Hill Blvd. :: San Antonio TX 78229-2263

Recombinant human luteinizing hormone :: Luveris :: For use in association with recombinant human follicle stimulating hormone for the treatment of women with chronic anovulation due to hypogonadotropic hypogonadism. :: Luveris (lutropin alfa for injection), concomitantly administered with Gonal-f (follitropin alfa for injection), is indicated for stimulation of follicular development in infertile hypogonadotropic hypogonadal women with profound LH deficiency (LH (less t :: 07-10-1994 :: 08-10-2004 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370

multi-vitiam infusion without vitamin K :: M.V.I.-12 :: "Prevention of vitamin deficiency and thromboembolic complications

in people receiving home parenteral nutrition and warfarin-type anticoagulant therapy

" :: Prevention of vitamin deficiency and thrombormbolic complications in people receiving home parenteral nutrition who also receive warfarin-type anticoagulant therapy :: 08-03-2004 :: 09-09-2004 :: Mayne Pharma (USA) Inc. :: Mack-Cali Centre II :: Second Floor :: Paramus NJ 07652

Diethylenetriaminepentaacetic acid (DTPA) :: Treatment of patients with known or suspected internal contamination with plutonium, americium, or curium to increase the rates of elimination. :: Treatment of internal contamination with plutonium, americium or curium :: 28-04-2004 :: 11-08-2004 :: Hameln Pharmaceuticals gmbh :: Langes Feld 13 :: Hameln :: GERMANY

Glutamine :: NutreStore :: For use with human growth hormone in the treatment of short bowel syndrome (nutrient malabsorption from the gastrointestinal tract resulting from an inadequate absorptive surface). :: Treatment of short bowel syndrome in patients receiving specialized nutritional support when used in conjunction with a rercombinant human growth hormone that is approved for this indication. :: 06-03-1995 :: 10-06-2004 :: Nutritional Restart Pharmaceutical, L.P. :: 4364 South Alston Avenue :: Durham NC 27713

azacitidine :: Vidaza :: Treatament of myelodysplastic syndromes :: Treatment of patients with the following myelodysplastic syndrome subtypes: refractory anemia or refractory anemia with ringed sideroblasts (if accompanied by neutropenia or thrombocytopenia and requiring transfusions), refractory anemia with excess blas :: 03-12-2001 :: 19-05-2004 :: Celgene Corporation :: 9900 W. 109th Street :: Suite 300 :: Overland Park KS 66210

tinidazole :: Tindamax :: Treatment of giardiasis :: Treatment of giardiasis caused by G. duodenalis (also termed G. lamblia) in both adults and pediatric patients older than three years of age :: 18-04-2002 :: 17-05-2004 :: Presutti Laboratories, Inc. :: 1607 N. Douglas Ave. :: Arlington Heights IL 60004

Tinidazole :: Tindamax :: Treatment of amebiasis :: Treatment of intestinal amebiasis and amebic liver abcess caused by E. histolytica in both adults and pediatric patients older than three years of age. It is not indicated for the treatment of asymptomatic cyst passage. :: 20-08-2003 :: 17-05-2004 :: Presutti Laboratories, Inc. :: 1607 N. Douglas Avenue :: Arlington Heights IL 60004

Apomorphine HCl :: Apokyn :: Treatment of the on-off fluctuations associated with late-stage Parkinson's disease. :: For the acute, intermittent treatment of hypomobility, "off" episodes ("end-of-dose-wearing-off" and unpredictable :on/off" episodes) associated with advanced Parkinson's disease :: 22-04-1993 :: 20-04-2004 :: Ipsen Limited :: 190 Bath Road :: Slough, Berkshire SL1 3XE :: UNITED KINGDOM

cinacalcet :: Sensipar :: Treatment of hypercalcemia in patients with parathyroid carcinoma :: Treatment of hypercalcemia in patients with parathyroid carcinoma :: 12-05-2003 :: 08-03-2004 :: Amgen, Inc. :: One Amgen Center Drive :: Thousand Oaks CA 91320-1799

pemetrexed disodium :: Alimta :: Treatment of malignant pleural mesothelioma :: Treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative surgery :: 28-08-2001 :: 04-02-2004 :: Eli Lilly and Company :: Lilly Corporate Center :: Indianapolis IN 46285

acetylcysteine :: Acetadote :: For the intravenous treatment of moderate to severe acetaminophen overdose :: For the use of Acetadote(registered TM) Injection, administered intravenously within 8 to 10 hours after ingestion of a potentially heptotoxic quantity of acetaminophen, to prevent or lessen hepatic injur :: 19-10-2001 :: 23-01-2004 :: Cumberland Pharmaceuticals, Inc. :: 209 10th Street South :: Suite 332 :: Nashville TN 37203

Somatropin (r-DNA) :: Zorbtive :: For use alone or in combination with glutamine in the treatment of short bowel syndrome. :: Treatment of short bowel syndrome in patients receiving specialized nutritional support :: 06-03-1995 :: 01-12-2003 :: EMD Serono, Inc. :: One Technology Place :: Roackland MA 02370

Botulism immune globulin :: BabyBIG :: Treatment of infant botulism. :: "Indicated for treatment of infant botulism caused by type A or type B Clostridium botulinum.

" :: 31-01-1989 :: 23-10-2003 :: California Department of Health Services :: 2151 Berkeley Way :: Berkeley CA 94704-1011

iron(III)-hexacyanoferrate(II) :: Radiogardase :: Treatment of patients with known or suspected internal contamination with radioactive or non-radioactive cesium or thallium :: Treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination :: 01-05-2003 :: 02-10-2003 :: Heyl Chemisch-Pharmzeutische Fabrik GMBH & Co, KG :: Goerzallee 253 :: D-14167 Berlin, Federal Republic of Germany :: GERMANY

porfimer :: Photofrin :: For the ablation of High-Grade Dysplasia in Barrett's Esophagus in patients who are not considered to be candidates for esophagectomy :: For the ablation of high-grade dysplasia in Barrett's esophagus patients who do not undergo esophagectomy :: 19-10-2001 :: 01-08-2003 :: Axcan Scandipharm Inc. :: 22 Inverness Parkway :: Suite 310 :: Birmingham AL 35242

miglustat :: Zavesca :: Treatment of Gaucher disease. :: Treatment of mild to moderate Type I Gaucher disease in adults for whom enzyme replacement therapy is not a therapeutic option (e.g., due to constraints such as allergy, hypersensitivity, or poor venous access). :: 29-05-1998 :: 31-07-2003 :: Actelion Pharmaceuticals Ltd :: Gewerbestrasse 16 :: CH – 4123 Allschwi :: SWITZERLAND

ribavirin :: REBETOL :: Treatment of chronic hepatitis C in pediatric patients :: Treatment of chronic hepatitis C among previously untreated pediatric patients at least three years of age or older. :: 04-04-2003 :: 29-07-2003 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033

Tositumomab and iodine I 131 tositumomab :: Bexxar :: Treatment of non-Hodgkin's B-cell lymphoma. :: Treatment of patients with CD20 positive, follicular, non-Hodgkin's lymphoma, with and without transformation, whose disease is refractory to Rituximab and has relapsed following chemotherapy :: 16-05-1994 :: 27-06-2003 :: GlaxoSmithKline :: 2301 Renaissance Blv. :: P.O. Box 61540 :: King of Prussia PA 19406-2772

bortezomib :: Velcade :: Treatment of multiple myeloma :: Treatment of multiple myeloma patients who have received at least two prior therapies and have demonstrated disease progression on the last therapy :: 15-01-2003 :: 13-05-2003 :: Millennium Pharmaceuticals, Inc. :: 40 Landsdowne Street :: Cambridge MA 02139

laronidase :: Aldurazyme :: Treatment of patients with mucopolysaccharidosis-I. :: Treatment for patients with Hurler and Hurler-Scheie forms of Mucopolysaccharidosis I (MPS I) and for patients with the Scheie form who have moderate to severe symptoms :: 24-09-1997 :: 30-04-2003 :: BioMarin Pharmaceutical, Inc. :: 371 Bel Marin Keys Boulevard, Suite 210 :: Novato CA 94949-5608

Ceramide trihexosidase/alpha-galactosidase A :: Fabrazyme :: Treatment of Fabry's disease. :: For use in patients with Fabry disease to reduce globotriaosylceramide (GL-3) deposition in capillary endothelium of the kidney and certain other cell types :: 19-01-1988 :: 24-04-2003 :: Genzyme Corporation :: One Kendall Square :: Cambridge MA 02139-1562

Pegvisomant :: Somavert :: Treatment of acromegaly. :: Treatment of acromegaly in patients who have had an inadequate response to surgery and/or radiation therapy and/or other medical therapies, or for whom these therapies are not appropriate :: 24-06-1997 :: 25-03-2003 :: Sensus Corporation :: Suite 430, :: 98 San Jacinto Boulevard :: Austin TX 78701

polifeprosan 20 with carmustine :: Gliadel :: Treatment of malignant glioma :: Expanding the indication to include patients with malignant glioma undergoing primary surgical resection. :: 13-12-1989 :: 25-02-2003 :: Guilford Pharmaceuticals, Inc. :: 6611 Tributary Street :: Baltimore MD 21224

Icodextrin 7.5% with Electrolytes Peritoneal Dialysis Solution :: Extraneal (with 7.5% Icodextrin) Peritoneal Dialysis Solutio :: Treatment of those patients having end stage renal disease and requiring peritoneal dialysis treatment. :: For use as a single daily exchange for the long (8-16 hour) dwell during continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) for the management of chronic renal failure. :: 18-07-1997 :: 20-12-2002 :: Baxter Healthcare Corporation :: Renal Division :: 1620 Waukegan Road :: McGaw Park IL 60085

nitazoxanide :: Alinia :: Treatment of intestinal giardiasis :: Treatment of diarrhea caused by Cryptosporidium parvum and Giardia lamblia :: 14-02-2002 :: 22-11-2002 :: Romark Laboratories, L.C. :: 6200 Courtney Campbell Causeway :: Suite 880 :: Tampa FL 33607

Nitazoxanide :: Alinia :: Treatment of cryptosporidiosis. :: Treatment of diarrhea caused by Cryptosporidium parvum and Giardia lamblia :: 12-12-1996 :: 22-11-2002 :: Romark Laboratories, L.C. :: 6200 Courtney Campbell Causeway :: Suite 880 :: Tampa FL 33607

Synthetic porcine secretin :: For use in the evaluation of exocrine pancreas function. :: For use in secretin stimulation testing for: Stimulation of pancreatic secretions to facilitate the identification of the ampulla of Vater and accessory papilla during endoscopic retrograde cholangio-pancreatography (ERCP) :: 18-06-1999 :: 01-11-2002 :: ChiRhoClin, Inc. :: 15500 Gallaudet Ave. :: Silver Spring MD 20905-4176

Buprenorphine hydrochloride :: Subutex :: Treatment of opiate addiction in opiate users. :: Treatment of opioid dependence in patients 16 years of age or older :: 15-06-1994 :: 08-10-2002 :: Reckitt Benckiser Pharmaceuticals, Inc. :: 1901 Huguenot Road :: Richmond VA 23235 ::

Buprenorphine in combination with naloxone :: Suboxone :: Treatment of opiate addiction in opiate users. :: Treatment of opioid dependence in patients 16 years of age or older :: 27-10-1994 :: 08-10-2002 :: Reckitt Benckiser Pharmaceuticals, Inc. :: 1901 Huguenot Road :: Richmond VA 23235

oxybate :: Xyrem :: Treatment of narcolepsy. :: Treatment of cataplexy associated with narcolepsy. :: 07-11-1994 :: 17-07-2002 :: Jazz Pharmaceuticals :: 3180 Porter Drive :: Palo Alto CA 94304

rasburicase :: Elitek :: Treatment of malignancy-associated or chemotherapy-induced hyperuricemia. :: Initial management of plasma uric acid levels in pediatric patients with leukemia,lymphoma, and solid tumor malignancies who are receiving anti-cancer therapy expected to result in tumor lysis and subsequent elevation of plasma uric acid. :: 11-10-2000 :: 12-07-2002 :: Sanofi-Synthelabo Research :: 9 Great Valley Parkway :: Malvern PA 19355

treprostinil :: Remodulin :: Treatment of pulmonary arterial hypertension. :: Treatment of pulmonary arterial hypertension. :: 04-06-1997 :: 21-05-2002 :: United Therapeutics Corp. :: 68 T.W. Alexander Dr. :: P.O. Box 14186 :: Research Triangle Park NC 27709

Synthetic porcine secretin :: For use in conjunction with diagnostic procedures for pancreatic disorders to increase pancreatic fluid secretion. :: Use in secretin stimulation testing for stimulation of pancreatic secretions, including bicarbonate, to aid in the diagnosis of pancreatic exocrine dysfunction :: 07-03-2000 :: 04-04-2002 :: ChiRhoClin, Inc. :: 15500 Gallaudet Ave. :: Silver Spring MD 20905-4176

Synthetic porcine secretin :: For use in the diagnosis of gastrinoma associated with Zollinger-Ellison syndrome. :: Use in secretin stimulation testing for stimulation of gastrin secretion to aid in the diagnosis of gastrinoma :: 18-06-1999 :: 04-04-2002 :: ChiRhoClin, Inc. :: 15500 Gallaudet Ave. :: Silver Spring MD 20905-4176

ibritumomab tiuxetan :: Zevalin :: Treatment of B-cell non-Hodgkin's lymphoma. :: Treatment of patients with relapsed or refractory low-grade, follicular, or transformed B-cell non-Hodgkin?s lymphoma, including patients with Rituximab (Rituxan?) refractory follicular non-Hodgkin?s lymphoma :: 06-09-1994 :: 19-02-2002 :: Cell Therapeutics, Inc. :: 501 Elliott Ave. W. :: Suite 400 :: Seattle WA 98119

imatinib mesylate :: Gleevec :: Treatment of gastrointestinal stromal tumors :: Treatment of patients with Kit (CD117) positive unresectable and/or metastatic malignant gastrointestinal stromal tumors (GIST) :: 01-11-2001 :: 01-02-2002 :: Novartis Pharmaceuticals Corp. :: One Health Plaza :: East Hanover NJ 07936-1080

Nitisinone :: Orfadin :: Treatment of tyrosinemia type 1. :: Adjunctive therapy to dietary restriction of tyrosine and phenylalanine in the treatment of hereditary tyrosinemia type 1 :: 16-05-1995 :: 18-01-2002 :: Swedish Orphan AB :: Drottninggatan 98 :: SE-111 60 Stockholm :: SWEDEN

Bosentan :: Tracleer :: Treatment of pulmonary arterial hypertension. :: Treatment of pulmonary arterial hypertension. :: 06-10-2000 :: 20-11-2001 :: Actelion Life Sciences Ltd. :: 1840 Gateway Dr. :: 2nd Floor :: San Mateo CA 94404

Topiramate :: Topamax :: Treatment of Lennox-Gastaut syndrome. :: As adjunctive therapy in patients two years and older with siezures associated with Lennox-Gastaut syndrome. :: 25-11-1992 :: 28-08-2001 :: Johnson & Johnson Pharmaceutical R & D, LLC :: Route 202, P.O. Box 300 :: Raritan NJ 08869-0602

Zoledronate :: Zometa, Zabel :: Treatment of tumor induced hypercalcemia. :: Treatment of hypercalcemia of malignancy. :: 18-08-2000 :: 20-08-2001 :: Novartis Pharmaceuticals Corp. :: 59 Route 10 :: East Hanover NJ 07936-1080

somatropin [rDNA] :: Genotropin :: Treatment of growth failure in children who were born small for gestational age. :: For long-term treatment of growth failure in children born small for gestational age who fail to manifest catch-up growth by two years of age. :: 27-12-2000 :: 25-07-2001 :: Pharmacia and Upjohn Company :: 7000 Portage Road :: Kalamazoo MI 49001

Imatinib :: Gleevec :: Treatment of chronic myelogenous leukemia :: "Treatment of patients with chronic myeloid

leukemia (CML) in blast crisis, accelerated phase, or in chronic phase after failure of interferon-alpha therapy" :: 31-01-2001 :: 10-05-2001 :: Novartis Pharmaceuticals Corporation :: 59 Route 10 :: East Hanover NJ 07936-1080

alemtuzumab :: Campath :: Treatment of chronic lymphocytic leukemia. :: The treatment of patients with B-cell chronic lymphocytic leukemia who have been treated with alkylating agents and who have failed fludarabine therapy. :: 20-10-1997 :: 07-05-2001 :: Genzyme Corporation :: 4545 Horizon Hill Blvd. :: San Antonio TX 78229-2263

Botulinum toxin type A :: Botox :: Treatment of cervical dystonia. :: Treatment of cervical dystonia in adults to decrease the severity of abnormal head position and neck pain associated with cervical dystonia. :: 20-08-1986 :: 21-12-2000 :: Allergan, Inc. :: 2525 Dupont Drive :: P.O. Box 19534 :: Irvine CA 92623-9534

Botulinum toxin type B :: Myobloc :: Treatment of cervical dystonia. :: Treatment of patients with cervical dystonia to reduce the severity of abnormal head position and neck pain associated with cervical dystonia. :: 16-01-1992 :: 08-12-2000 :: Solstice Neurosciences, Inc. :: 40 General Warren Blvd :: Suite 160 :: Malvern PA 19355

Fomepizole :: Antizole :: Treatment of methanol or ethylene glycol poisoning. :: Use for suspected or confirmed methanol poisoning, either alone or in combination with hemodialysis :: 22-12-1988 :: 08-12-2000 :: Jazz Pharmaceuticals :: 3180 Porter Drive :: Palo Alto CA 94304

Mitoxantrone :: Novantrone :: Treatment of secondary-progressive multiple sclerosis. :: Reducing neurologic disability and/or the frequency of clinical relapses in patients with secondary (chronic) progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis (i.e., patients whose neurologic status is significantly :: 13-08-1999 :: 13-10-2000 :: Serono, Inc. :: One Technoloogy Place :: Rockland MA 02370

Mitoxantrone :: Novantrone :: Treatment of progressive-relapsing multiple sclerosis. :: Reducing neurologic disability and/or the frequency of clinical relapses in patients with secondary (chronic) progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis (i.e., patients whose neurologic status is significantly :: 13-08-1999 :: 13-10-2000 :: Serono, Inc. :: One Technology Place :: Rockland MA 02370

Antivenin, crotalidae polyvalent immune Fab (ovine) :: CroFab :: Treatment of envenomations inflicted by North American crotalid snakes. :: Carol Clark-Evans direct line (615) 963-4510 :: 12-01-1994 :: 02-10-2000 :: Protherics, Inc. :: 1207 17th Ave. S., Suite 103 :: Nashville TN 37212

Arsenic trioxide :: Trisenox :: Treatment of acute promyelocytic leukemia. :: For induction of remission and consolidation in patients with acute promyelocytic leukemia (APL) who are refractory to, or have relapsed from, retinoid and anthracycline chemotherapy, and whose APL is characterized by the presence of the t(15;17) transloc :: 03-03-1998 :: 25-09-2000 :: Cephalon :: 41 Moores Road :: PO Box 4011 :: Frazer PA 19355

Somatropin [rDNA] :: Genotropin :: Treatment of short stature in patients with Prader-Willi syndrome. :: Long-term treatment of pediatric patients who have growth failure due to Prader-Willi syndrome (PWS). :: 06-07-1999 :: 20-06-2000 :: Pharmacia & Upjohn :: 7000 Portage Rd. :: 0633-298-113 :: Kalamazoo MI 49001-0199

Follitropin alfa, recombinant :: Gonal-F :: For the initiation and re-initiation of spermatogenesis in adult males with reproductive failure due to hypothalamic or pituitary dysfunction, hypogonadotropic hypogonadism. AMENDED indication 6/27/00: For the induction of spermatogenesis in men with pr :: For the induction of spermatogenesis in men with primary and secondary hypogonadotropic hypogonadism in whom the cause of infertility is not due to primary testicular failure. :: 21-12-1998 :: 24-05-2000 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370

Gemtuzumab zogamicin :: Mylotarg :: Treatment of CD33-positive acute myeloid leukemia. :: Treatment of patients with CD33 positive acute myeloid leukemia in first relapse who are 60 years of age or older and who are not considered candidates for cytotoxic chemotherapy :: 24-11-1999 :: 17-05-2000 :: Wyeth-Ayerst Laboratories :: PO Box 8299 :: Philadelphia PA 19101-8299

Epoprostenol :: Flolan :: Treatment of secondary pulmonary hypertension due to intrinsic precapillary pulmonary vascular disease. :: For the long-term intravenous treatment of pulmonary hypertension associated with the scleroderma spectrum of disease in New York Heart Association (NYHA) Class III and Class IV patients who do not respond adequately to conventional therapy. :: 22-03-1999 :: 14-04-2000 :: GlaxoSmithKline :: Five Moore Dr. :: PO Box 13398 :: Research Triangle Park NC 27709-3398

Interferon gamma-1b :: Actimmune :: Delaying time to disease progression in patients with severe, malignant osteopetrosis. :: Delaying time to disease progression in patients with severe, malignant osteopetrosis. :: 30-09-1996 :: 10-02-2000 :: InterMune , Inc. :: 1710 Gilbreth Road, :: Suite 301 :: Burlingame CA 94010-1317

Bexarotene :: Targretin :: Treatment of cutaneous T-cell lymphoma. :: Treatment of cutaneous manifestations of cutaneous T-cell lymphoma in patients who are refractory to at least one prior systemic therapy. :: 18-06-1999 :: 29-12-1999 :: Eisai Medical Research, Inc. :: 55 Challenger Road :: Ridgefield Park NJ 07660

Nitric oxide :: INOmax :: Treatment of persistent pulmonary hypertension in the newborn. :: In conjunction with ventilatory support and other appropriate agents, in the treatment of term and near-term (>34 weeks) neonates with hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension, where it i :: 22-06-1993 :: 23-12-1999 :: INO Therapeutics, Inc. :: 54 Old Highway 22 :: Clinton NJ 08809

Levocarnitine :: Carnitor :: Treatment of manifestations of carnitine deficiency in patients with end stage renal disease who require dialysis. :: Prevention and treatment of carnitine deficiency in patients with end stage renal disease who are undergoing dialysis. :: 06-09-1988 :: 15-12-1999 :: Sigma-Tau Pharmaceuticals, Inc. :: 9841 Washingtonian Blvd :: Suite 500 :: Gaithersburg MD 20878

Exemestane :: Aromasin :: Treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy. :: Treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy. :: 19-09-1991 :: 21-10-1999 :: Pharmacia & Upjohn :: 7000 Portage Road :: Mail Stop: 0636-298-113 :: Kalamazoo MI 49001-0199

Caffeine :: Cafcit :: Treatment of apnea of prematurity. :: Short term treatment of apnea of prematurity in infants between 28 and less than 33 weeks gestational age. :: 20-09-1988 :: 21-09-1999 :: O.P.R. Development, L.P. :: 1501 Wakarusa Drive :: Lawrence KS 66047

Epirubicin :: Ellence :: Treatment of breast cancer. :: Component of adjuvant therapy in patients with evidence of axillary node tumor involvement following resection of primary breast cancer. :: 14-09-1999 :: 15-09-1999 :: Pharmacia & Upjohn Company :: 0634-298-113 :: 7000 Portage Rd. :: Kalamazoo MI 49001-0199

Temozolomide :: Temodar :: Treatment of recurrent malignant glioma. :: Treatment of adult patients with refractory anaplastic astrocytoma, i.e., patients at first relapse who have experienced disease progression on a drug regimen containing a nitrosourea and procarbazine. :: 05-10-1998 :: 11-08-1999 :: Schering-Plough Research Institute :: 2000 Galloping Hill Rd. :: Kenilworth NJ 07033

Doxorubicin liposome :: Doxil :: Treatment of ovarian cancer. :: Treatment of metastatic carcinoma of the ovary in patients with disease that is refractory to both paclitaxel- and platinium-based chemotherapy regimens. Refractory disease is defined as disease that has progressed while on treatment, or within 6 months :: 04-11-1998 :: 28-06-1999 :: Alza Corporation :: 1550 Plymouth St. :: PO Box 7210 :: Mountain View CA 94039-7210

Amifostine :: Ethyol :: Reduction of the incidence of moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer. :: Reduction of the incidence of moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer, where the radiation port includes a substantial portion of the parotid glands. :: 12-05-1998 :: 24-06-1999 :: Medimmune Oncology, Inc. :: One Tower Bridge :: 100 Front Street, Suite 400 :: Conshohocken PA 19428

etanercept :: Enbrel :: "Reduction in signs and symptoms of moderately to severely active polyarticular-course juvenile rheumatoid arthritis in patients who have had an inadequate response to one or more disease-modifying anti-rheumatic drugs.

" :: "Reduction in signs and symptoms of moderately to severely active polyarticular-course juvenile rheumatoid arthritis in patients who have had an inadequate response to one or more disease-modifying anti-rheumatic drugs.

" :: 27-10-1998 :: 27-05-1999 :: Immunex Corporation :: 51 University St. :: Seattle WA 98101-2936

Antihemophilic factor/von Willebrand factor complex (human), dried, pasteurized :: Humate-P :: "Treatment of patients with von Willebrand's disease

" :: (1) In adult patients for treatment and prevention of bleeding in hemophilia A (classic hemophilia) and (2) in adult and pediatric patients for treatment of spontaneous and trauma-induced bleeding episodes in severe von Willebrand disease, and in mild and :: 16-10-1992 :: 01-04-1999 :: Aventis Behring L.L.C. :: 1020 First Avenue :: PO Box 61501 :: King Of Prussia PA 19406-0901

Cytarabine liposomal :: DepoCyt :: Treatment of neoplastic meningitis. :: Intrathecal treatment of lymphomatous meningitis. :: 02-06-1993 :: 01-04-1999 :: Pacira Pharmaceuticals, Inc. :: 10450 Science Center Drive :: San Diego CA 92121

Coagulation factor VIIa (recombinant) :: NovoSeven :: Treatment of bleeding episodes in hemophilia A or B patients with inhibitors to Factor VIII or Factor IX. :: Treatment of bleeding episodes in hemophilia A or B patients with inhibitors to Factor VIII or Factor IX. :: 06-06-1988 :: 25-03-1999 :: Novo Nordisk, Inc. :: 100 Overlook Center :: Suite 200 :: Princeton NJ 08540-7810

Lidocaine patch 5% :: Lidoderm Patch :: For relief of allodynia (painful hypersensitivity), and chronic pain in postherpetic neuralgia. :: 24-10-1995 :: 19-03-1999 :: Teikoku Pharma USA, Inc. :: 745-D Camden Ave. :: Campbell CA 95008-4146

denileukin diftitox :: Ontak :: Treatment of patients with cutaneous T-cell lymphoma :: Treatment of patients with persistent or recurrent cutaneous T-cell lymphoma whose malignant cells express the CD25 component of the IL-2 receptor. :: 21-08-1996 :: 05-02-1999 :: Eisai Medical Research, Inc. :: 55 Challenger Road :: Ridgefield Park NJ 07660

Busulfan :: Busulfex :: As preparative therapy in the treatment of malignancies with bone marrow transplantation. :: For use in combination with cyclophosphamide as a conditioning regimen prior to allogeneic hematopoietic progenitor cell transplantation for chronic myelogenous leukemia. :: 28-07-1994 :: 04-02-1999 :: Otsuka Pharmaceutical Company :: Tokyo :: JAPAN

Alitretinoin :: Panretin :: Treatment of AIDS-related Kaposi's sarcoma. :: Topical treatment of cutaneous lesions in patients with AIDS-related Kaposi's sarcoma. :: 24-03-1998 :: 02-02-1999 :: Eisai Medical Research, Inc :: 55 Challenger Road :: Ridgefield Park NJ 07660

Atovaquone :: Mepron :: Prevention of Pneumocystis carinii pneumonia (PCP) in high-risk, HIV-infected patients defined by a history of one or more episodes of PCP and/or a peripheral CD4+ (T4 helper/inducer) lymphocyte count less than or equal to 200/mm3. :: Prevention of PCP in patients who are intolerant to trimethoprim-sulfamethoxazole. :: 14-08-1991 :: 05-01-1999 :: Glaxo Wellcome Research and Development :: 5 Moore Drive :: PO Box 13398 :: Research Triangle Park NC 27709

Modafinil :: Provigil :: Treatment of excessive daytime sleepiness in narcolepsy. :: Improve wakefulness in patients with excessive daytime sleepiness associated with narcolepsy. :: 15-03-1993 :: 24-12-1998 :: Cephalon, Inc. :: 145 Brandywine Parkway :: West Chester PA 19380

Cytomegalovirus immune globulin (human) :: CytoGam :: Prevention or attenuation of primary cytomegalovirus disease in immunosuppressed recipients of organ transplants. :: #1) Attenuation of primary CMV disease associated with kidney transplant recipients who are seronegative for CMV and who receive a kidney from a CMV seropositve donor; #2) Prophylaxis of CMV disease associated transplantation of kidney (all other), lung, :: 03-08-1987 :: 04-12-1998 :: Massachussetts Public Health Biologic Laboratories :: 305 South Street :: Boston MA 02130-3597

Thyrotropin alpha :: Thyrogen :: As an adjunct in the diagnosis of thyroid cancer. :: As an adjunctive diagnostic tool for serum thyroglobulin (Tg) testing with or without radioiodine imaging in the follow-up of patients with thyroid cancer. :: 24-02-1992 :: 30-11-1998 :: Genzyme Corporation :: One Kendall Square :: Cambridge MA 02139

Octreotide :: Sandostatin LAR :: Treatment of severe diarrhea and flushing associated with malignant carcinoid tumors. :: Supression of severe diarrhea and flushing associated with malignant carcinoid syndrome. :: 24-08-1998 :: 25-11-1998 :: Novartis Pharmaceuticals Corporation :: 59 Route 10 :: East Hanover NJ 07936-1080

Octreotide :: Sandostatin LAR :: Treatment of acromegaly. :: Reduction of growth hormone and IGF-1 (somatomedin C) in acromegaly. :: 24-08-1998 :: 25-11-1998 :: Novartis Pharmaceuticals Corporation :: 59 Route 10 :: East Hanover NJ 07936-1080

Octreotide :: Sandostatin LAR :: Treatment of diarrhea associated with vasoactive intestinal peptide tumors (VIPoma). :: Treatment of profuse watery diarrhea associated with VIPoma. :: 24-08-1998 :: 25-11-1998 :: Novartis Pharmaceuticals Corporation :: 59 Route 10 :: East Hanover NJ 07936-1080

Valrubicin :: Valstar :: Treatment of carcinoma in situ of the urinary bladder. :: For intravesical therapy of BCG-refractory carcinoma in situ of the urinary bladder in patients for whom immediate cystectomy would be associated with unacceptable morbidity or mortality. :: 23-05-1994 :: 25-09-1998 :: Anthra Pharmaceuticals, Inc. :: 103 Carnegie Center, Suite 102 :: Princeton NJ 08540

Infliximab :: Remicade :: Treatment of moderately to severely active Crohn's disease for the reduction of the signs and symptoms, in patients who have an inadequate response to conventional therapy; and treatment of patients with fistulizing Crohn's disease for the reduction in th :: Treatment of moderately to severely active Crohn's disease for the reduction of the signs and symptoms, in patients who have an inadequate response to conventional therapies; and treatment of patients with fistulizing Crohn's disease for the reduction in :: 14-11-1995 :: 24-08-1998 :: Centocor, Inc. :: 200 Great Valley Parkway :: Malvern PA 19355-1307

Lamotrigine :: Lamictal :: Treatment of Lennox-Gastaut syndrome. :: Adjunctive treatment of Lennox-Gastaut syndrome in pediatric and adult patients. :: 23-08-1995 :: 24-08-1998 :: Glaxo Wellcome Research and Development :: 5 Moore Drive :: P.O. Box 13398 :: Research Triangle Park NC 27709

Thalidomide :: Thalomid :: Treatment of erythema nodosum leprosum. :: Acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL) and as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrences. :: 26-07-1995 :: 16-07-1998 :: Celgene Corporation :: 86 Morris Avenue :: Summit NJ 07901

Rifapentine :: Priftin :: Treatment of pulmonary tuberculosis. :: 09-06-1995 :: 22-06-1998 :: Hoechst Marion Roussel :: P.O. Box 9627 :: Mail Station: H3-M2516 :: Kansas City MO 64134-0627

Mafenide acetate solution :: Sulfamylon solution :: For use as an adjunctive topical antimicrobial agent to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. :: 18-07-1990 :: 05-06-1998 :: Mylan Laboratories, Inc. :: 781 Chestnut Ridge Road :: P.O. Box 4310 :: Morgantown WV 26504-4310

Basiliximab :: Simulect :: "Prophylaxis of solid organ rejection.

" :: "Prophylaxis of acute organ rejection in patients receiving renal transplantation when used as part of an immunosuppressive regimen that includes cyclosporine and corticosteroids.

" :: 12-12-1997 :: 12-05-1998 :: Novartis Pharmaceuticals Corporation :: 59 Route 10 :: East Hanover NJ 07936-1080

Sacrosidase :: Sucraid :: Treatment of congenital sucrase-isomaltase deficiency. :: Oral replacement therapy of the genetically determined sucrase deficiency, which is part of congenital sucrease-isomaltase deficiency. :: 10-12-1993 :: 09-04-1998 :: QOL Medical, LLC :: 12419 198th Drive, NE :: Woodinville WA 98072

Filgrastim :: Neupogen :: Reduction in the duration of neutropenia, fever, antibiotic use, and hospitalization, following induction and consolidation treatment for acute myeloid leukemia. :: Reducing the time to neutrophil recovery and the duration of fever, following induction or consolidation chemotherapy treatment of adults with acute myeloid leukemia. :: 07-11-1996 :: 02-04-1998 :: Amgen, Inc. :: One Amgen Center Dr. :: Thousand Oaks CA 91320-1799

Lepirudin :: Refluden :: Treatment of heparin-associated thrombocytopenia type II. :: For anticoagulation in patients with heparin-induced thrombocytopenia and associated thromboembolic disease in order to prevent further thromboembolic complications. :: 13-02-1997 :: 06-03-1998 :: Hoechst Marion Roussel :: Frankfurt am Main :: P.O. Box 1140 :: Marburg :: GERMANY

Hydroxyurea :: Droxia :: Treatment of patients with sickle cell anemia as shown by the presence of hemoglobin S. :: To reduce the frequency of painful crises and to reduce the need for blood transfusions in adult patients with sickle cell anemia with recurrent moderate to severe painful crises (generally at least 3 during the preceding 12 months). :: 01-10-1990 :: 25-02-1998 :: Bristol-Myers Squibb Pharmaceutical Research Institute :: P.O. Box 4000 :: Princeton NJ 08543

Pilocarpine HCl :: Salagen :: Treatment of xerostomia and keratoconjunctivitis sicca in Sjogren's syndrome patients. :: Treatment of dry mouth in patients with Sjogren's syndrome. :: 28-02-1992 :: 11-02-1998 :: MGI Pharma, Inc. :: 5775 West Old Shakopee Rd. :: Suite 100 :: Bloomington MN 55437-3107

Aldesleukin :: Proleukin :: Treatment of metastatic melanoma. :: Treatment of adults with metastatic melanoma. :: 10-09-1996 :: 09-01-1998 :: Chiron Corporation :: 4560 Horton Street :: Emeryville CA 94608-2916

Sterile talc powder :: Sclerosol Intrapleural Aerosol :: Treatment of malignant pleural effusion. :: Prevention of recurrence of malignant pleural effusions in symptomatic patients. :: 18-09-1995 :: 24-12-1997 :: Bryan Corporation :: 4 Plympton Street :: Woburn MA 01801

Tobramycin for inhalation :: TOBI :: Treatment of bronchopulmonary infections of Pseudomonas aeruginosa in cystic fibrosis patients. :: Management of cystic fibrosis patients with P.aeruginosa. :: 13-10-1994 :: 22-12-1997 :: Novartis Pharmaceuticals Corp :: Drug Regulatory Affairs :: One Health Plaza :: East Hanover NJ 07936-1080

Somatropin for injection :: Nutropin :: As replacement therapy for growth hormone deficiency in adults after epiphyseal closure. :: 18-11-1996 :: 15-12-1997 :: Genentech, Inc. :: 460 Point San Bruno Boulevard :: South San Francisco CA 94080

Daclizumab :: Zenapax :: Prevention of acute renal allograft rejection. :: Prophylaxis of acute organ rejection in patients receiving renal transplants, to be used as a part of an immunosuppressive regimen that includes cyclosporine and corticosteroids. :: 05-03-1993 :: 10-12-1997 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110

Ursodiol :: URSO :: Treatment of patients with primary biliary cirrhosis. :: 20-06-1991 :: 10-12-1997 :: Axcan Pharma Inc. :: 597 Laurier Blvd :: Mount St. Hilaire Quebec H7L 4S3 ::

Fomepizole :: Antizole :: Treatment of methanol or ethylene glycol poisoning. :: As an antidote to ethylene glycol (antifreeze) poisoning, or for use in suspected ethylene glycol ingestion. :: 22-12-1988 :: 04-12-1997 :: Jazz Pharmaceuticals :: 3180 Porter Drive :: Palo Alto CA 94304

rituximab :: Rituxan :: Treatment of non-Hodgkin's B-cell lymphoma. :: 13-06-1994 :: 26-11-1997 :: Genentech, Inc. :: 1 DNA Way, MS 242 :: South San Francisco CA 94080-4990

Oprelvekin :: Neumega :: Prevention of severe chemotherapy-induced thrombocytopenia. :: 17-12-1996 :: 25-11-1997 :: Genetics Institute, Inc. :: 87 Cambridge Park Drive :: Cambridge MA 02140

Somatropin :: Genotropin :: Treatment of adults with growth hormone deficiency. :: 06-09-1994 :: 31-10-1997 :: Pharmacia & Upjohn :: 7000 Portage Road :: Kalamazoo MI 49001-0199

Sermorelin acetate :: Geref :: Treatment of idiopathic or organic growth hormone deficiency in children with growth failure. :: 14-09-1988 :: 26-09-1997 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370

Liposomal amphotericin B :: AmBisome :: Treatment of visceral leishmaniasis. :: Treatment of visceral leishmaniasis. :: 06-12-1996 :: 11-08-1997 :: Fujisawa USA, Inc. :: 3 Parkway North Center :: Deerfield IL 60015

Liposomal amphotericin B :: AmBisome :: Treatment of cryptococcal meningitis. :: Treatment of disseminated cryptococcosis including meningitis. :: 10-12-1996 :: 11-08-1997 :: Fujisawa USA, Inc. :: 3 Parkway North Center :: Deerfield IL 60015

Paclitaxel :: Taxol :: Treatment of AIDS-related Kaposi's sarcoma. :: For the second line treatment of AIDS-related Kaposi's sarcoma. :: 25-03-1997 :: 04-08-1997 :: Bristol-Myers Squibb Pharmaceutical Research Institute :: 5 Research Parkway :: P.O. Box 5100 :: Wallingford CT 06492-7660

Diazepam viscous solution for rectal administration :: For the management of selected, refractory, patients with epilepsy, on stable regimens of antiepileptic drugs (AEDs), who require intermittent use of diazepam to control bouts of increased seizure activity. :: 25-02-1992 :: 29-07-1997 :: Valeant Pharmaceuticals :: 3300 Hyland Avenue :: Costa Mesa CA 92626

Toremifene :: Fareston :: Hormonal therapy of metastatic carcinoma of the breast. :: Treatment of metastatic breast cancer in postmenopausal women with estrogen positive or receptor unknown tumors. :: 19-09-1991 :: 29-05-1997 :: Orion Corporation :: P.O. Box 65 :: 02101 ESPOO :: FINLAND

Anagrelide :: Agrylin :: Treatment of essential thrombocythemia. :: Treatment of patients with essential thrombocythemia to reduce the elevated platelet count and the risk of thrombosis and to ameliorate associated symptoms. :: 27-01-1988 :: 14-03-1997 :: Roberts Pharmaceutical Corp. :: Meridian Center III :: 6 Industrial Way West :: Eatontown NJ 07724

Coagulation Factor IX (recombinant) :: BeneFix :: Treatment of hemophilia B. :: For the control and prevention of hemorrhagic episodes in patients with hemophilia B (congenital factor IX deficiency and Christmas disease), including control and prevention of bleeding in surgical settings. :: 03-10-1994 :: 11-02-1997 :: Genetics Institute, Inc. :: 87 Cambridge Park Drive :: Cambridge MA 02140

Zinc acetate :: Galzin :: Treatment of Wilson's disease. :: For maintenance treatment of patients with Wilson's disease who have been initially treated with a chelating agent. :: 06-11-1985 :: 28-01-1997 :: Lemmon Company :: 1510 Delp Drive :: Kulpsville PA 19443

Somatropin :: Humatrope :: Treatment of short stature associated with Turner syndrome. :: Treatment of short stature associated with Turner syndrome in patients whose epiphyses are not closed. :: 08-05-1990 :: 30-12-1996 :: Eli Lilly and Company :: Lilly Corporate Center :: Indianapolis IN 46285

Somatropin for injection :: Nutropin :: Treatment of short stature associated with Turner's syndrome. :: Treatment of growth failure associated with Turner syndrome. :: 23-03-1989 :: 30-12-1996 :: Genentech, Inc. :: 460 Point San Bruno Boulevard :: South San Francisco CA 94080

Glatiramer acetate :: Copaxone :: Treatment of multiple sclerosis. :: For reduction of the frequency of relapses in patients with relapsing-remitting multiple sclerosis. :: 09-11-1987 :: 20-12-1996 :: Teva Pharmaceuticals USA :: 1510 Delp Drive :: Kulpsville PA 19443

Mitoxantrone :: Novantrone :: Treatment of hormone refractory prostate cancer. :: In combination with corticosteroids as initial chemotherapy for the treatment of patients with pain related to advanced hormone-refractory prostate cancer. :: 21-08-1996 :: 13-11-1996 :: Serono :: One Technology Place :: Rockland MA 02370

Betaine :: Cystadane :: Treatment of homocystinuria. :: Treatment of homocystinuria to decrease elevated homocysteine blood levels. :: 16-05-1994 :: 25-10-1996 :: Jazz Pharmaceuticals :: 3180 Porter Drive :: Palo Alto CA 94304

Amphotericin B lipid complex :: Abelcet :: Treatment of invasive fungal infections. :: Treatment of invasive fungal infections in patients who are refractory to or intolerant of conventional amphotericin B therapy. :: 05-12-1991 :: 18-10-1996 :: Liposome Company, Inc. :: One Research Way :: Princeton NJ 08540

Clonidine :: Duraclon :: For continous epidural administration as adjunctive therapy with intraspinal opiates for the treatment of pain in cancer patients tolerant to, or unresponsive to, intraspinal opiates. :: In combination with opiates for the treatment of severe pain in cancer patients that is not adequately relieved by opioid analgesics alone. :: 24-01-1989 :: 02-10-1996 :: Roxane Laboratories, Inc. :: PO Box 16532 :: Columbus OH 43216-6532

Buffered intrathecal electrolyte/dextrose injection :: Elliotts B Solution :: For use as a diluent in the intrathecal administration of methotrexate and cytarabine for the prevention or treatment meningeal leukemia and lymphocytic lymphoma. :: For the intrathecal administration of methotrexate and cytarabine for the prevention or treatment of meningeal leukemia and lymphocytic lymphoma. :: 24-08-1994 :: 27-09-1996 :: QOL Medical, LLC :: 12419 198th Drive, NE :: Woodinville WA 98072

Pentosan polysulfate sodium :: Elmiron :: Treatment of interstitial cystitis. :: Relief of bladder pain or discomfort associated with interstitial cystitis. :: 07-08-1985 :: 26-09-1996 :: Alza Corporation :: 950 Page Mill Rd. :: PO Box 10950 :: Palo Alto CA 94303-0802

polifeprosan 20 with carmustine :: Gliadel :: Treatment of malignant glioma. :: As an adjunct to surgery to prolong survival in patients with recurrent glioblastoma multiforme for whom surgical resection is indicated :: 13-12-1989 :: 23-09-1996 :: Guilford Pharmaceuticals, Inc. :: 6611 Tributary Street :: Baltimore MD 21224

Midodrine HCl :: Amatine :: Treatment of patients with symptomatic orthostatic hypotension. :: Treatment of symptomatic orthostatic hypotension. :: 05-12-1996 :: 06-09-1996 :: Schier Ridgewood F.K.A. (Roberts Pharmaceutical Corp.) :: Meridian Center III :: 6 Industrial Way West :: Eatontown NJ 07724

Somatropin for injection :: Serostim :: Treatment of AIDS-associated catabolism/weight loss. :: Treatment of AIDS wasting or cachexia. :: 15-11-1991 :: 23-08-1996 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370

Fosphenytoin :: Cerebyx :: For the acute treatment of patients with status epilepticus of the grand mal type. :: For the control of generalized convulsive status epilepticus. :: 04-06-1991 :: 05-08-1996 :: Warner-Lambert Company :: 2800 Plymouth Road :: Ann Arbor MI 48106

Albendazole :: Albenza :: Treatment of neurocysticercosis due to Taenia solium as: 1) chemotherapy of parenchymal, subarachnoidal and racemose (cysts in spinal fluid) neurocysticercosis in symptomatic cases and 2) prophylaxis of epilepsy and other sequelae in asymptomatic neurocys :: Treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium. :: 18-01-1996 :: 11-06-1996 :: SmithKline Beecham Pharmaceuticals :: One Franklin Plaza :: P.O. Box 7929 :: Philadelphia PA 19101

Albendazole :: Albenza :: Treatment of hydatid disease (cystic echinococcosis due to E. granulosus larvae or alveolar echinococcosis due to E. multilocularis larvae). :: Treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus. :: 17-01-1996 :: 11-06-1996 :: SmithKline Beecham Pharmaceuticals :: One Franklin Plaza :: P.O. Box 7929 :: Philadelphia PA 19101

Corticorelin ovine triflutate :: Acthrel :: For use in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushings syndrome. :: To differentiate between pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome. :: 24-11-1989 :: 23-05-1996 :: Ferring Laboratories, Inc. :: 400 Rella Boulevard, Suite 201 :: Suffern NY 10901

Ofloxacin :: Ocuflox Ophthalmic Solution :: Treatment of bacterial corneal ulcers. :: Treatment of bacterial corneal ulcers. :: 18-04-1991 :: 22-05-1996 :: Allergan, Inc. :: 2525 Dupont Drive :: P.O. Box 19534 :: Irvine CA 92713

Allopurinol sodium :: Aloprim for Injection :: Management of patients with leukemia, lymphoma, and solid tumor malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels and who cannot tolerate oral therapy. :: Management of patients with leukemia, lymphoma, and solid tumor malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels and who cannot tolerate oral therapy. :: 16-10-1992 :: 17-05-1996 :: Catalytica Pharmaceuticals, Inc :: PO Box 1887 :: Greenville NC 27835-1887

Interferon beta-1a :: Avonex :: Treatment of multiple sclerosis. :: Treatment of relapsing forms of multiple sclerosis to slow the accumulation of physical disability and decrease the frequency of clinical exacerbations. :: 16-12-1991 :: 17-05-1996 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142

sodium phenylbutyrate :: Buphenyl :: Treatment of urea cycle disorders: carbamylphosphate synthetase deficiency, ornithine transcarbamylase deficiency, and arginiosuccinic acid synthetase deficiency. :: Adjunctive therapy in the chronic managment of patients with urea cycle disorders involving deficiencies of carbamylphosphate synthetase, ornithine transcarbamylase, or argininosuccinic acid synthetase. :: 22-11-1993 :: 30-04-1996 :: Medicis Pharmaceutical Corp. :: 8125 N. Hayden Road :: Scottsdale AZ 85258

Daunorubicin citrate liposome injection :: DaunoXome :: Treatment of patients with advanced HIV-associated Kaposi's sarcoma. :: First line cytotoxic therapy for advanced, HIV related Kaposi's sarcoma. :: 14-05-1993 :: 08-04-1996 :: NeXstar Pharmaceuticals, Inc. :: 650 Cliffside Drive :: San Dimas CA 91773

Ganciclovir intravitreal implant :: Vitrasert Implant :: Treatment of cytomegalovirus retinitis. :: Treatment of CMV retinitis in patients with acquired immunodeficiency syndrome. :: 07-06-1995 :: 04-03-1996 :: Bausch & Lomb Surgical, Chiron Vision Products :: 9342 Jeronimo Road :: Irvine CA 92718-1903

Bleomycin sulfate :: Blenoxane :: Treatment of malignant pleural effusion. :: Treatment of malignant pleural effusion. :: 17-09-1993 :: 20-02-1996 :: Bristol-Myers Squibb Pharmaceutical Research Institute :: P.O. Box 4000 :: Princeton NJ 08543

Respiratory syncytial virus immune globulin (Human) :: Respigam :: Prophylaxis of respiratory syncytial virus lower respiratory tract infections in infants and young children at high risk of RSV disease. :: For the prevention of serious lower respiratory tract infections caused by RSV in children less than 24 months of age with bronchopulmonary dysplasia or a history of prematurity (less than or equal to 35 weeks gestation). :: 27-09-1990 :: 18-01-1996 :: MedImmune & Massachussetts Public Health Biologics Labs. :: 35 West Watkins Mill Road :: Gaithersburg MD 20878

Filgrastim :: Neupogen :: For use in the mobilization of peripheral blood progenitor cells for collection in patients who will receive myeloablative or myelosuppressive chemotherapy. :: For use in the mobilization of hematopoietic progenitor cells into the peripheral blood collection by leukapheresis. :: 17-07-1995 :: 28-12-1995 :: Amgen, Inc. :: 1840 Dehavilland Drive :: Thousand Oaks CA 91320

Porfimer sodium :: Photofrin :: For the photodynamic therapy of patients with primary or recurrent obstructing (either partially or completely) esophageal carcinoma. :: Photodynamic therapy with PHOTOFRIN for the palliation of patients with completely obstructing esophageal cancer, or of patients with partially obstructing esophageal cancer who cannot be satisfactorily treated with Nd:YAG laser therapy. :: 06-06-1989 :: 27-12-1995 :: QLT Phototherapeutics, Inc. :: Lederle Laboratories :: 401 North Middletown Road :: Pearl River NY 10965

Riluzole :: Rilutek :: Treatment of amyotrophic lateral sclerosis. :: Treatment of patients with amyotrophic lateral sclerosis. Riluzole extends survival and/or time to tracheostomy. :: 16-03-1993 :: 12-12-1995 :: Rhone-Poulenc Rorer Pharmaceuticals, Inc. :: 500 Arcola Road, P.O. Box 1200 :: Collegeville PA 19426

Amifostine :: Ethyol :: For use as a chemoprotective agent for cisplatin in the treatment of advanced ovarian carcinoma. :: To reduce the cumulative renal toxicity associated with repeated administration of cisplatin in patients with advanced ovarian cancer. :: 30-05-1990 :: 08-12-1995 :: Medimmune Oncology, Inc. :: One Tower Bridge :: 100 Front Street, Suite 400 :: West Conshohocken PA 19428

Tretinoin :: Vesanoid :: Treatment of acute promyelocytic leukemia. :: Induction of remission in patients with acute promyelocytic leukemia who are refractory to or unable to tolerate anthracycline based cytotoxic chemotherapeutic regimens. :: 24-10-1990 :: 22-11-1995 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110

Interferon alfa-2a :: Roferon A :: Treatment of chronic myelogenous leukemia. :: Treatment of chronic myelogenous leukemia. :: 06-06-1989 :: 19-10-1995 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110

Epoprostenol :: Flolan :: Treatment of primary pulmonary hypertension. :: Long-term intravenous treatment of primary pulmonary hypertension in NYHA Class III and Class IV patients. :: 25-09-1985 :: 20-09-1995 :: Glaxo Wellcome Inc. :: 5 Moore Drive :: Research Triangle Park NC 27709

Sargramostim :: Leukine :: To reduce neutropenia and leukopenia and decrease the incidence of death due to infection in patients with acute myelogenous leukemia. :: Following induction chemotherapy in older adult patients with acute myelogenous leukemia to shorten time to neutrophil recovery and to reduce the incidence of severe and life-threatening infections and infections resulting in death. :: 06-03-1995 :: 15-09-1995 :: Immunex Corporation :: 51 University Street :: Seattle WA 98101

Amiodarone HCl :: Cordarone :: For the acute treatment and prophylaxis of life-threatening ventricular tachycardia or ventricular fibrillation. :: For initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients refractory to other therapy. :: 16-03-1994 :: 03-08-1995 :: Wyeth-Ayerst Laboratories :: P.O. Box 8299 :: Philadelphia PA 19101

Dexrazoxane :: Zinecard :: For the prevention of cardiomyopathy associated with doxorubicin administration. :: Cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative dose of 300mg/m2. :: 17-12-1991 :: 26-05-1995 :: Pharmacia & Upjohn :: 7000 Portage Road :: Kalamazoo MI 49001-0199

Rho (D) immune globulin intravenous (human) :: WinRho SD :: Treatment of immune thrombocytopenic purpura. :: Treatment of adults and children with chronic and acute immune thrombocytopenic purpura. :: 09-11-1993 :: 24-03-1995 :: Rh Pharmaceuticals, Inc. :: 104 Chancellor Matheson Road :: Winnipeg, Manitoba :: CANADA

Filgrastim :: Neupogen :: Treatment of patients with severe chronic neutropenia (absolute neutrophil count less than 500/mm3). :: Treatment of patients with severe chronic neutropenia. :: 07-11-1990 :: 19-12-1994 :: Amgen, Inc. :: 1840 Dehavilland Drive :: Thousand Oaks CA 91320

Cysteamine :: Cystagon :: Treatment of nephropathic cystinosis. :: Treatment of nephropathic cystinosis in adults and children. :: 25-01-1991 :: 15-08-1994 :: Mylan Laboratories, Inc. :: 781 Chestnut Ridge Road :: P.O. Box 4310 :: Morgantown WV 26504

Sulfadiazine :: "For use in combination with pyrimethamine for the treatment of Toxoplasma gondii

encephalitis in patients with and without AIDS." :: Toxoplasmosis, as adjunctive with pyrimethamine :: 14-03-1994 :: 29-07-1994 :: Eon Labs Manufacturing, Inc. :: 227-15 North Conduit Avenue :: Laurelton NY 11413

Aminosalicylic acid :: Paser Granules :: Treatment of tuberculosis infections :: Treatment of tuberculosis :: 19-02-1992 :: 30-06-1994 :: Jacobus Pharmaceutical Company :: 37 Cleveland Lane :: P.O. Box 5290 :: Princeton NJ 08540

Filgrastim :: Neupogen :: Treatment of neutropenia associated with bone marrow transplants. :: Reduce the duration of neutropenia and neutropenia sequelae in patients with non-myeloid malignancies undergoing ablative chemotherapy followed by BMT. :: 01-10-1990 :: 15-06-1994 :: Amgen, Inc. :: 1840 Dehavilland Drive :: Thousand Oaks CA 91320

Rifampin, isoniazid, pyrazinamide :: Rifater :: For the short-course treatment of tuberculosis. :: Short-course treatment of tuberculosis. :: 12-09-1985 :: 31-05-1994 :: Hoechst Marion Roussel :: P.O. Box 9627 :: Kansas City MO 64134

Imiglucerase :: Cerezyme :: Replacement therapy in patients with types I, II, and III Gaucher's disease. :: Enzyme replacement therapy in patients with type I Gaucher's disease. :: 05-11-1991 :: 23-05-1994 :: Genzyme Corporation :: One Kendall Square :: Cambridge MA 02139-1562

Pilocarpine :: Salagen :: Treatment of xerostomia induced by radiation therapy for head and neck cancer. :: Treatment of symptoms of xerostomia from salivary gland hypofunction caused by radiotherapy for cancer of the head and neck. :: 24-09-1990 :: 22-03-1994 :: MGI Pharma, Inc. :: 5775 West Old Shakopee Rd. :: Suite 100 :: Bloomington MN 55437-3107

Desmopressin acetate :: Treatment of mild hemophilia A and von Willebrand's disease. :: Treatment of patients with hemophilia A or von Willebrand's disease (type I) whose factor VIII coagulant activity level is greater than 5%. :: 22-01-1991 :: 07-03-1994 :: Aventis Behring L.L.C. :: 1020 First Avenue :: PO Box 61501 :: King of Prussia PA 19406-0901

Pegaspargase :: Oncaspar :: Treatment of acute lymphocytic leukemia. :: Combination chemotherapy for the treatment of patients with acute lymphoblastic leukemia who are hypersensitive to native forms of L-asparaginase. :: 20-10-1989 :: 01-02-1994 :: Enzon, Inc. :: 20 Kingsbridge Road :: Piscataway NJ 08854

Dornase alfa :: Pulmozyme :: To reduce mucous viscosity and enable the clearance of airway secretions in patients with cystic fibrosis. :: In conjunction with standard therapies in the management of cystic fibrosis patients to reduce the frequency of respiratory infections requiring parenteral antibiotics and to improve pulmonary function. :: 16-01-1991 :: 30-12-1993 :: Genentech, Inc. :: 460 Point San Bruno Boulevard :: South San Francisco CA 94080

Aprotinin :: Trasylol :: For prophylactic use to reduce perioperative blood loss and the homologous blood transfusion requirement in patients undergoing cardiopulmonary bypass surgery in the course of repeat coronary artery bypass graft surgery, and in selected cases of primary c :: 17-11-1993 :: 29-12-1993 :: Bayer Corporation :: Pharmaceutical Division :: 400 Morgan Lane :: West Haven CT 06516

Immune globulin intravenous, human :: Gamimune N :: Infection prophylaxis in pediatric patients affected with the human immunodeficiency virus. :: For prophylaxis of children with clinical or immunologic evidence of human immunodeficiency virus to decrease the frequency of serious and minor bacterial infections and the frequency of hospitalization, and to increase the time free of serious bacterial :: 18-02-1993 :: 27-12-1993 :: Bayer Corporation :: Pharmaceutical Division, Biological Products :: 400 Morgan Lane :: New Haven CT 06516

Trimetrexate glucuronate :: Neutrexin :: Treatment of Pneumocystis carinii pneumonia in AIDS patients. :: Concurrent leucovorin administration as an alternative therapy for the treatment of moderate to severe PCP in immunocompromised patients who are intolerant of, or are refractory to, trimethoprim sulfamethoxazole. :: 15-05-1986 :: 17-12-1993 :: Medimmune Oncology, Inc. :: One Tower Bridge :: 100 Front Street, Suite 400 :: West Conshohocken PA 19428

Somatropin for injection :: Nutropin :: Treatment of growth retardation associated with chronic renal failure. :: Treatment of children with growth failure associated with chronic renal insufficency. :: 04-08-1989 :: 17-11-1993 :: Genentech, Inc. :: 460 Point San Bruno Boulevard :: South San Francisco CA 94080

Lodoxamide tromethamine :: Alomide Ophthalmic Solution :: Treatment of vernal keratoconjunctivitis. :: Treatment of ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, vernal keratitis. :: 16-10-1991 :: 23-09-1993 :: Alcon Laboratories, Inc. :: 6201 South Freeway :: Fort Worth TX 76134

Megestrol acetate :: Megace :: Treatment of patients with anorexia, cachexia, or significant weight loss (=/>10% of baseline body weight) and confirmed diagnosis of AIDS. :: Treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with a diagnosis of acquired immune deficiency syndrome. :: 13-04-1988 :: 10-09-1993 :: Bristol-Myers Squibb Pharmaceutical Research Institute :: 2400 West Lloyd Expressway :: Evansville IN 47721

Felbamate :: Felbatol :: Treatment of Lennox-Gastaut syndrome. :: As adjunctive therapy in the treatment of partial and generalized seizures associated with the Lennox-Gastaut syndrome in children. :: 24-01-1989 :: 29-07-1993 :: Wallace Laboratories :: 301B College Road East :: Princeton NJ 08540

Interferon beta-1b :: Betaseron :: Treatment of multiple sclerosis. :: In ambulatory patients with relapsing-remitting multiple sclerosis to reduce the frequency of clinical exacerbations. :: 17-11-1988 :: 23-07-1993 :: Chiron Corp. & Berlex Laboratories :: 4560 Horton Street :: Emeryville CA 94608

Levomethadyl acetate hydrochloride :: Orlaam :: Treatment of heroin addicts suitable for maintenance on opiate agonists. :: For the management of opiate dependence. :: 24-01-1985 :: 09-07-1993 :: Biodevelopment Corporation :: 8180 Greensboro Drive, Suite 1000 :: McLean VA 22102

Leuprolide acetate :: Lupron Injection :: Treatment of central precocious puberty. :: Treatment of children with central precocious puberty. :: 25-07-1988 :: 16-04-1993 :: Tap Pharmaceuticals, Inc. :: 2355 Waukegan Road :: Deerfield IL 60015

Cladribine :: Leustatin Injection :: Treatment of hairy cell leukemia. :: 15-11-1990 :: 26-02-1993 :: R. W. Johnson Pharmaceutical Research Institute :: Route 202, P.O. Box 300 :: Raritan NJ 08869

Antihemophilic factor (recombinant) :: Kogenate :: Prophylaxis and treatment of bleeding in individuals with hemophilia A or for prophylaxis when surgery is required in individuals with hemophilia A. :: Treatment and prophylaxis of bleeding in patients with hemophilia A (not von Willebrand's disease) :: 25-09-1989 :: 25-02-1993 :: Bayer Corporation :: 1884 Miles Avenue :: Elkhart IN 46515

Satumomab pendetide :: Oncoscint CR/OV :: Detection of ovarian carcinoma. :: For determining the extent and location of extraphepatic malignant disease in patients with known colorectal and ovarian cancer. :: 25-09-1989 :: 29-12-1992 :: Cytogen Corporation :: 600 College Road East :: Princeton NJ 08540

Rifabutin :: Mycobutin :: Prevention of disseminated Mycobacterium avium complex disease in patients with advanced HIV infection. :: Prevention of disseminated Mycobacterium avium complex disease in patients with advanced HIV infections. :: 18-12-1989 :: 23-12-1992 :: Adria Laboratories, Inc. :: P.O. Box 16529 :: Columbus OH 43216

Dronabinol :: Marinol :: For the stimulation of appetite and prevention of weight loss in patients with a confirmed diagnosis of AIDS. :: Treatment of anorexia associated with weight loss in patients with AIDS. :: 15-01-1991 :: 22-12-1992 :: Unimed Pharmaceuticals, Inc. :: 901 Sawyer Rd. :: Marietta GA 30062

Levocarnitine :: Carnitor :: Treatment of primary and secondary carnitine deficiency of genetic origin. :: "Treatment of primary systemic carnitine deficiency. (approved 12/27/85)

Treatment of secondary carnitine deficiency. (approved 12/16/92)" :: 26-07-1984 :: 16-12-1992 :: Sigma-Tau Pharmaceuticals, Inc. :: 9841 Washingtonian Blvd. :: Suite 500 :: Gaithersburg MD 20878

Atovaquone :: Mepron :: Treatment of AIDS associated Pneumocystis Carinii Pneumonia. :: For the acute oral treatment of mild to moderate Pneumocystis carinii pneumonia in patients who are intolerant to trimethoprim-sulfamethoxazole. :: 10-09-1990 :: 25-11-1992 :: Glaxo Wellcome Inc. :: 5 Moore Drive :: Research Triangle Park NC 27709

Melphalan :: Alkeran For Injection :: Treatment of patients with multiple myeloma for whom oral therapy is inappropriate. :: For the palliative treatment of patients with multiple myeloma for whom oral melphalan is not appropriate. :: 24-02-1992 :: 18-11-1992 :: Glaxo Wellcome Inc. :: 5 Moore Drive :: Research Triangle Park NC 27709

Sotalol HCl :: Betapace :: Treatment of life-threatening ventricular tachyarrhythmias. :: 23-09-1988 :: 30-10-1992 :: Berlex Laboratories, Inc. :: 300 Fairfield Road :: Wayne NJ 07470

Coagulation factor IX :: Mononine :: Replacement treatment and prophylaxis of the hemorrhagic complications of hemophilia B. :: Prevention and control of bleeding in factor IX deficiency, also known as hemophilia B or Christmas disease. :: 27-06-1989 :: 20-08-1992 :: Armour Pharmaceutical Company :: 500 Arcola Road, P.O. Box 1200 :: Collegeville PA 19426

Halofantrine :: Halfan :: Treatment of mild to moderate acute malaria caused by susceptible strains of P. falciparum and P. vivax. :: Treatment of adults who can tolerate oral medication and who have mild to moderate malaria caused by Plasmodium falciparum or Plasmodium vivax. :: 04-11-1991 :: 24-07-1992 :: SmithKline Beecham Pharmaceuticals :: One Franklin Plaza :: P.O. Box 7929 :: Philadelphia PA 19101

Teniposide :: Vumon for injection :: Treatment of refractory childhood acute lymphocytic leukemia. :: Induction therapy in patients with refractory childhood acute lymphoblastic leukemia when used in combination with other approved anticancer agents. :: 01-11-1984 :: 14-07-1992 :: Bristol-Myers Squibb Pharmaceutical Research Institute :: 5 Research Parkway :: P.O. Box 5100 :: Wallingford CT 06492

Baclofen :: Lioresal Intrathecal :: Treatment of intractable spasticity caused by spinal cord injury, multiple sclerosis, and other spinal diseases (including spinal ischemia, spinal tumor, transverse myelitis, cervical spondylosis, and degenerative myelopathy). :: Management of severe spasticity of spinal cord origin in patients who are unresponsive to oral baclofen therapy or experience intolerable CNS side effects at effective doses. :: 10-11-1987 :: 25-06-1992 :: Medtronic, Inc. :: 800 53rd Avenue N.E. :: Minneapolis MN 55432

Zalcitabine :: Hivid :: Treatment of AIDS. :: Combination therapy with zidovudine is indicated for the treatment of adult patients with advanced HIV infection (CD4 count < 300) who have demonstrated malignant clinical or immunologic deterioration. :: 28-06-1988 :: 19-06-1992 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110

Aldesleukin :: Proleukin :: Treatment of metastatic renal cell carcinoma. :: Treatment of adults (>18 years old) with metastatic renal cell carcinoma. :: 14-09-1988 :: 05-05-1992 :: Chiron Corporation :: 4560 Horton Street :: Emeryville CA 94608-2916

Nafarelin acetate :: Synarel Nasal Solution :: Treatment of central precocious puberty. :: Treatment of central precocious puberty (gonadotropin-dependent precocious puberty) in children of both sexes. :: 20-07-1988 :: 26-02-1992 :: Syntex (USA), Inc. :: 3401 Hillview Avenue :: Palo Alto CA 94303

Liothyronine sodium injection :: Triostat :: Treatment of myxedema coma/precoma. :: Treatment of myxedema coma/precoma. :: 30-07-1990 :: 31-12-1991 :: SmithKline Beecham Pharmaceuticals :: One Franklin Plaza :: P.O. Box 7929 :: Philadelphia PA 19101

Antithrombin III (human) :: Thrombate III :: For replacement therapy in congenital deficiency of AT-III for prevention and treatment of thrombosis and pulmonary emboli. :: 26-11-1984 :: 30-12-1991 :: Bayer Corporation :: Pharmaceutical Division, Biological Products :: 400 Morgan Lane :: New Haven CT 06516

Histrelin acetate :: Supprelin Injection :: Treatment of central precocious puberty. :: Treatment of central precocious puberty. :: 10-08-1988 :: 24-12-1991 :: Roberts Pharmaceutical Corp. :: Meridian Center III :: 6 Industrial Way West :: Eatontown NJ 07724

Leucovorin :: Leucovorin calcium :: For use in combination with 5-fluorouracil for the treatment of metastatic colorectal cancer. :: For use in combination with 5-fluorouracil to prolong survival in the palliative treatment of patients with advanced colorectal cancer. :: 08-12-1986 :: 12-12-1991 :: Immunex Corporation :: 51 University Street :: Seattle WA 98101

Pentostatin for injection :: Nipent :: Treatment of hairy cell leukemia. :: Single agent treatment for adult patients with alpha-interferon-refractory hairy cell leukemia. :: 10-09-1987 :: 11-10-1991 :: SuperGen, Inc. :: 4140 Dublin Blvd. :: Suite 200 :: Dublin CA 94568

Morphine sulfate concentrate (preservative free) :: Infumorph :: For use in microinfusion devices for intraspinal administration in the treatment of intractable chronic pain. :: For intrathecal or epidural infusion in the treatment of tractable chronic pain. It was developed for use in continuous microinfusion devices and may require dilution before use as directed. :: 12-07-1990 :: 19-07-1991 :: Elkins-Sinn, Inc. :: 2 Esterbrook Lane :: Cherry Hill NJ 08003

Beractant :: Survanta intratracheal suspension :: Prevention of neonatal respiratory distress syndrome. :: Prevention of RDS (hyaline membrane disease) in premature infants less than 1250 grams birthweight or with evidence of surfactant deficiency. :: 05-02-1986 :: 01-07-1991 :: Ross Laboratories :: 625 Cleveland Avenue :: Columbus OH 43215

Beractant :: Survanta intratracheal suspension :: Treatment of neonatal respiratory distress syndrome. :: Treatment of ("rescue") of premature infants with RDS confirmed by x-ray and requiring mechanical ventilation. :: 05-02-1986 :: 01-07-1991 :: Ross Laboratories :: 625 Cleveland Avenue :: Columbus OH 43215

Fludarabine phosphate :: Fludara :: Treatment of chronic lymphocytic leukemia (CLL), including refractory CLL. :: 18-04-1989 :: 18-04-1991 :: Berlex Laboratories, Inc. :: 15049 San Pablo Avenue, P.O. Box 4099 :: Richmond CA 94804

Alglucerase injection :: Ceredase :: For replacement therapy in patients with Gaucher's disease type I. :: "Long-term enzyme replacement therapy for children, adolescents and adult patients with a confirmed diagnosis of Type I Gaucher disease who

exhibit signs and symptoms that are severe enough to result in one or more of the following conditions:

a) moderate-" :: 11-03-1985 :: 05-04-1991 :: Genzyme Corporation :: One Kendall Square :: Cambridge MA 02139-1562

Sargramostim :: Leukine :: Treatment of neutropenia associated with bone marrow transplant, for the treatment of graft failure and delay of engraftment, and for the promotion of early engraftment. :: 03-05-1990 :: 05-03-1991 :: Immunex Corporation :: 51 University Street :: Seattle WA 98101

Gallium nitrate injection :: Ganite :: Treatment of hypercalcemia of malignancy. :: 05-12-1988 :: 17-01-1991 :: Solopak Pharmaceutical Co. :: 1845 Tonne Road :: Elk Grove Village IL 60007

Coagulation Factor IX (human) :: AlphaNine :: For use as replacement therapy in patients with hemophilia B for the prevention and control of bleeding episodes, and during surgery to correct defective hemostasis. :: 05-07-1990 :: 31-12-1990 :: Alpha Therapeutic Corporation :: 5555 Valley Boulevard :: Los Angeles CA 90032

Epoetin alfa :: Epogen :: Treatment of anemia associated with HIV infection or HIV treatment. :: Treatment of AZT-induced anemia in HIV infected patients. :: 01-07-1991 :: 31-12-1990 :: Amgen, Inc. :: 1840 Dehavilland Drive :: Thousand Oaks CA 91320

Altretamine :: Hexalen :: Treatment of advanced adenocarcinoma of the ovary. :: Single agent palliative treatment of patients with persistent or recurrent ovarian cancer following first-line therapy with a cisplatin and/or alkylating agent based combination. :: 09-02-1984 :: 26-12-1990 :: Medimmune Oncology, Inc. :: One Tower Bridge :: 100 Front Street, Suite 400 :: Conshohocken PA 19428

Interferon gamma 1-b :: Actimmune :: Treatment of chronic granulomatous disease. :: 30-09-1988 :: 20-12-1990 :: InterMune, Inc. :: 3280 Bayshore Blvd :: Brisbane CA 94005

Calcium acetate :: Phos-Lo :: Treatment of hyperphosphatemia in end stage renal failure. :: 22-12-1988 :: 10-12-1990 :: Fresenius Medical Care North America :: 920 Winter Street :: Waltham MA 02451

Eflornithine HCl :: Ornidyl :: Treatment of Trypanosoma brucei gambiense infection (sleeping sickness). :: 23-04-1986 :: 28-11-1990 :: Hoechst Marion Roussel :: P.O. Box 9627 :: Kansas City MO 64134

Citric acid, glucono-delta-lactone and magnesium carbonate :: Renacidin Irrigation :: Treatment of renal and bladder calculi of the apatite or struvite variety. :: 28-08-1989 :: 02-10-1990 :: United-Guardian, Inc. :: P.O. Box 2500 :: Smithtown NY 11787

Idarubicin HCl for injection :: Idamycin :: Treatment of acute myelogenous leukemia, also referred to as acute nonlymphocytic leukemia. :: 25-07-1988 :: 27-09-1990 :: Adria Laboratories, Inc. :: P.O. Box 16529 :: Columbus OH 43216

Colfosceril palmitate, cetyl alcohol, tyloxapol :: Exosurf Neonatal for Intratracheal Suspension :: Treatment of established hyaline membrane disease at all gestational ages. :: 20-10-1989 :: 02-08-1990 :: Glaxo Wellcome Inc. :: 5 Moore Drive :: Research Triangle Park NC 27709

Colfosceril palmitate, cetyl alcohol, tyloxapol :: Exosurf Neonatal for Intratracheal Suspension :: Prevention of hyaline membrane disease, also known as respiratory distress syndrome, in infants born at 32 weeks gestation or less. :: 20-10-1989 :: 02-08-1990 :: Glaxo Wellcome Inc. :: 5 Moore Drive :: Research Triangle Park NC 27709

Iobenguane Sulfate I 131 :: For use as a diagnostic adjunct in patients with pheochromocytoma. :: Adjunctive diagnostic agent in the localization of primary or metastatic pheochromocytomas. :: 14-11-1984 :: 21-03-1990 :: University of Michigan :: UH B1 H410/0028 :: 1500 E. Medical Center Drive :: Ann Arbor MI 48109-0028

Pegademase bovine :: Adagen :: For enzyme replacement therapy for ADA deficiency in patients with severe combined immunodeficiency. :: 29-05-1984 :: 21-03-1990 :: Enzon, Inc. :: 20 Kingsbridge Road :: Piscataway NJ 08854

Botulinum toxin type A :: Botox :: Treatment of strabismus associated with dystonia in adults (patients 12 years of age and above). :: 22-03-1984 :: 29-12-1989 :: Allergan, Inc. :: 2525 Dupont Drive :: P.O. Box 19534 :: Irvine CA 92713

Botulinum toxin type A :: Botox :: Treatment of blepharospasm associated with dystonia in adults (patients 12 years of age and above). :: 22-03-1984 :: 29-12-1989 :: Allergan, Inc. :: 2525 Dupont Drive :: P.O. Box 19534 :: Irvine CA 92713

Cromolyn sodium :: Gastrocrom :: Treatment of mastocytosis. :: 08-03-1984 :: 22-12-1989 :: Fisons Corporation :: 755 Jefferson Rd :: P.O. Box 1710 :: Rochester NY 14603

Antithrombin III (human) :: ATnativ :: For the treatment of patients with hereditary antithrombin III deficiency in connection with surgical or obstetrical procedures or when they suffer from thromboembolism. :: 08-02-1985 :: 13-12-1989 :: Pharmacia & Upjohn AB :: Lindhagensgatan 133 :: SE-112 87 :: SWEDEN

Gonadorelin acetate :: Lutrepulse :: For induction of ovulation in women with hypothalamic amenorrhea due to a deficiency or absence in the quantity or pulse pattern of endogenous GnRH secretion. :: 22-04-1987 :: 10-10-1989 :: Ferring Laboratories, Inc. :: 400 Rella Boulevard, Suite 201 :: Suffern NY 10901

Ganciclovir sodium :: Cytovene :: Treatment of cytomegalovirus retinitis in immunocompromised patients with AIDS. :: 31-10-1985 :: 23-06-1989 :: Syntex (USA), Inc. :: 3401 Hillview Avenue :: Palo Alto CA 94304

Pentamidine isethionate :: Nebupent :: Prevention of Pneumocystis carinii pneumonia in patients at high risk of developing this disease. :: 12-01-1988 :: 15-06-1989 :: Fujisawa USA, Inc. :: 3 Parkway North Center :: Deerfield IL 60015

Selegiline HCl :: Eldepryl :: As an adjuvant to levodopa and carbidopa treatment of idiopathic Parkinson's disease (paralysis agitans), postencephalitic Parkinsonism, and symptomatic Parkinsonism. :: 07-11-1984 :: 05-06-1989 :: Somerset Pharmaceuticals, Inc. :: 777 South Harbor Island Boulevard :: Tampa FL 33602

Epoetin alfa :: Epogen :: Treatment of anemia associated with end stage renal disease. :: 10-04-1986 :: 01-06-1989 :: Amgen, Inc. :: 1840 Dehavilland Drive :: Thousand Oaks CA 91320

Rifampin :: Rifadin I.V. :: For antituberculosis treatment where use of the oral form of the drug is not feasible. :: 09-12-1985 :: 25-05-1989 :: Hoechst Marion Roussel :: P.O. Box 9627 :: Kansas City MO 64134

Mefloquine HCl :: Lariam :: Prophylaxis of Plasmodium falciparum malaria which is resistant to other available drugs. :: 13-04-1988 :: 02-05-1989 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110

Mefloquine HCl :: Lariam :: Treatment of acute malaria due to Plasmodium falciparum and Plasmodium vivax. :: 13-04-1988 :: 02-05-1989 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110

Ifosfamide :: Ifex :: Treatment of testicular cancer. :: In combination with certain other approved antineoplastic agents, for third line chemotherapy in the treatment of germ cell testicular cancer. :: 20-01-1987 :: 30-12-1988 :: Bristol-Myers Squibb Pharmaceutical Research Institute :: 5 Research Parkway, P.O. Box 5100 :: Wallingford CT 06492

Mesna :: Mesnex :: For use as a prophylactic agent in reducing the incidence of ifosfamide-induced hemorrhagic cystitis. :: 14-11-1985 :: 30-12-1988 :: Degussa Corporation :: 65 Challenger Road :: Ridgefield Park NJ 07660

Ethanolamine oleate :: Ethamolin :: Treatment of patients with esophageal varices that have recently bled, to prevent rebleeding. :: 22-03-1984 :: 22-12-1988 :: Block Drug Company, Inc. :: 257 Cornelison Avenue :: Jersey City NJ 07302

Succimer :: Chemet capsules :: Treatment of lead poisoning in children. :: 09-05-1984 :: 22-12-1988 :: Bock Pharmacal Company :: P.O. Box 419056 :: Saint Louis MO 63141-9056

Metronidazole (topical) :: Metrogel :: Treatment of acne rosacea. :: 22-10-1987 :: 22-11-1988 :: Galderma Laboratories, Inc. :: P.O. Box 331329 :: Fort Worth TX 76163

Interferon alfa-2a (recombinant) :: Roferon-A :: Treatment of AIDS related Kaposi's sarcoma. :: 14-12-1987 :: 21-11-1988 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110

Interferon alfa-2b (recombinant) :: Intron A :: Treatment of AIDS-related Kaposi's sarcoma. :: Treatment of selected patients with AIDS-related Kaposi's sarcoma. :: 24-06-1987 :: 21-11-1988 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033

Leucovorin :: Leucovorin calcium :: For rescue use after high dose methotrexate therapy in the treatment of osteosarcoma. :: 17-08-1988 :: 31-08-1988 :: Immunex Corporation :: 51 University Street :: Seattle WA 98101

Tiopronin :: Thiola :: Prevention of cystine nephrolithiasis in patients with homozygous cystinuria. :: 17-01-1986 :: 11-08-1988 :: Pak, Charles Y.C. M.D. :: The University of Texas Health Scienc Center at Da :: 5323 Harry Hines Boulevard :: Dallas TX 75235

Methotrexate sodium :: Methotrexate :: Treatment of osteogenic sarcoma. :: For the use of high dose methotrexate with leucovorin rescue in patients with non-metastatic osteosarcoma who have undergone surgical resection or amputation for the primary tumor. :: 21-10-1985 :: 07-04-1988 :: Lederle Laboratories :: Division of American Cyanamid Company :: 401 N. Middletown Road :: Pearl River NY 10965

Benzoate and phenylacetate :: Ucephan :: For adjunctive therapy in the prevention and treatment of hyperammonemia in patients with urea cycle enzymopathy due to carbamylphosphate synthetase, ornithine, transcarbamylase, or argininosuccinate synthetase deficiency. :: 21-01-1986 :: 23-12-1987 :: "Immunex

Immunex" :: 2525 McGaw Avenue :: P.O. Box 19791 :: Irvine CA 92623

Mitoxantrone HCl :: Novantrone :: Treatment of acute myelogenous leukemia, also referred to as acute nonlymphocytic leukemia. :: 13-07-1987 :: 23-12-1987 :: Lederle Laboratories :: Division of American Cyanamid Company :: 401 N. Middletown Road :: Pearl River NY 10965

Teriparatide :: Parathar :: Diagnostic agent to assist in establishing the diagnosis in patients presenting with clinical and laboratory evidence of hypocalcemia due to either hypoparathyroidism or pseudohypoparathyroidism. :: 09-01-1987 :: 23-12-1987 :: Rhone-Poulenc Rorer Pharmaceuticals, Inc. :: 500 Arcola Road :: Collegeville PA 19426

Alpha1-proteinase inhibitor (human) :: Prolastin :: For replacement therapy in the alpha-1-proteinase inhibitor congenital deficiency state. :: For chronic replacement therapy of individuals having congenital deficiency of alpha1- proteinase inhibitor with clinically demonstrable panacinar emphysema. :: 07-12-1984 :: 02-12-1987 :: Bayer Corporation :: Pharmaceutical Division, Biological Products :: 400 Morgan Lane :: New Haven CT 06516

Pentastarch :: Pentaspan :: As an adjunct in leukapheresis to improve the harvesting and increase the yield of leukocytes by centrifugal means. :: 28-08-1985 :: 19-05-1987 :: Du Pont Pharmaceuticals :: E.I. Du Pont De Nemours & Co. :: Wilmington DE 19898

Etidronate disodium :: Didronel :: Treatment of hypercalcemia of malignancy inadequately managed by dietary modification and/or oral hydration. :: 21-03-1986 :: 21-04-1987 :: MGI Pharma, Inc. :: 5775 West Old Shakoppe Rd. :: Suite 100 :: Bloomington MN 55437-3107

Zidovudine :: Retrovir :: Treatment of AIDS. :: 17-07-1985 :: 19-03-1987 :: Glaxo Wellcome Inc. :: 5 Moore Drive :: Research Triangle Park NC 27709

Zidovudine :: Retrovir :: Treatment of AIDS related complex. :: 17-07-1985 :: 19-03-1987 :: Glaxo Wellcome Inc. :: 5 Moore Drive :: Research Triangle Park NC 27709

Somatropin for injection :: Humatrope :: For the long-term treatment of children who have growth failure due to inadequate secretion of normal endogenous growth hormone. :: 12-06-1986 :: 08-03-1987 :: Eli Lilly and Company :: Lilly Corporate Center :: Indianapolis IN 46285

Tranexamic acid :: Cyklokapron :: Treatment of patients with congenital coagulopathies who are undergoing surgical procedures (e.g. dental extractions). :: 29-10-1985 :: 30-12-1986 :: Pharmacia Inc. :: P.O. Box 16529 :: Columbus OH 43216

Clofazimine :: Lamprene :: Treatment of lepromatous leprosy, including dapsone-resistant lepromatous leprosy and lepromatous leprosy complicated by erythema nodosum leprosum. :: 11-06-1984 :: 15-12-1986 :: Novartis Pharmaceutical Corporation :: 59 Route 10 :: East Hanover NJ 07936

Calcitonin-human for injection :: Cibacalcin :: Treatment of symptomatic Paget's disease (osteitis deformans). :: 20-01-1987 :: 31-10-1986 :: Novartis Pharmaceutical Corporation :: 59 Route 10 :: East Hanover NJ 07936

Urofollitropin :: Metrodin :: For induction of ovulation in patients with polycystic ovarian disease who have an elevated LH/FSH ratio and who have failed to respond to adequate clomiphene citrate therapy. :: 25-11-1987 :: 18-09-1986 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370

Digoxin immune FAB (Ovine) :: Digibind :: Treatment of potentially life threatening digitalis intoxication in patients who are refractory to management by conventional therapy. :: 01-11-1984 :: 22-04-1986 :: Glaxo Wellcome Inc. :: 5 Moore Drive :: Research Triangle Park NC 27709

Levocarnitine :: Carnitor :: Treatment of genetic carnitine deficiency. :: 28-02-1984 :: 10-04-1986 :: Sigma-Tau Pharmaceuticals, Inc. :: 9841 Washingtonian Blvd :: Suite 500 :: Gaithersburg MD 20878

Trientine HCl :: Syprine :: Treatment of patients with Wilson's disease who are intolerant, or inadequately responsive to penicillamine. :: 24-12-1984 :: 08-11-1985 :: Merck Sharp & Dohme Research :: Division Of Merck And Company :: West Point PA 19486

Monooctanoin :: Moctanin :: For dissolution of cholesterol gallstones retained in the common bile duct. :: 30-05-1984 :: 31-10-1985 :: Ethitek Pharmaceuticals, Inc. :: 7855 Gross Point Road, Unit L :: Skokie IL 60077

Somatrem for injection :: Protropin :: For long-term treatment of children who have growth failure due to a lack of adequate endogenous growth hormone secretion. :: 09-12-1985 :: 17-10-1985 :: Genentech, Inc. :: 460 Point San Bruno Boulevard :: South San Francisco CA 94080

Somatropin :: Nutropin :: For use in the long-term treatment of children who have growth failure due to a lack of adequate endogenous growth hormone secretion. :: 06-03-1987 :: 17-10-1985 :: Genentech, Inc. :: 460 Point San Bruno Boulevard :: South San Francisco CA 94080

Potassium citrate :: Urocit-K :: For avoidance of the complication of calcium stone formation in patients with uric lithiasis. :: 01-11-1984 :: 30-08-1985 :: University of Texas Health Science Center at Dallas :: 5323 Harry Hines Blvd :: Dallas TX 75235

Potassium citrate :: Urocit-K :: Prevention of calcium renal stones in patients with hypocitraturia. :: 01-11-1984 :: 30-08-1985 :: University of Texas Health Science Center at Dallas :: 5323 Harry Hines Blvd :: Dallas TX 75235

Potassium citrate :: Urocit-K :: Prevention of uric acid nephrolithiasis. :: 01-11-1984 :: 30-08-1985 :: University of Texas Health Science Center at Dallas :: 5323 Harry Hines Boulevard :: Dallas TX 75235

Naltrexone HCl :: Trexan :: For blockade of the pharmacological effects of exogenously administered opioids as an adjunct to the maintenance of the opioid-free state in detoxified formerly opioid-dependent individuals. :: 11-03-1985 :: 30-11-1984 :: DuPont Pharmaceuticals :: E.I. Du Pont De Nemours & Co. :: Wilmington DE 19880

Pentamidine isethionate :: Pentam 300 :: Treatment of Pneumocystis carinii pneumonia. :: 28-02-1984 :: 16-10-1984 :: Fujisawa USA, Inc. :: 3 Parkway North Center :: Deerfield IL 60015

Cromolyn sodium 4% ophthalmic solution :: Opticrom 4% ophthalmic solution :: Treatment of vernal keratoconjunctivitis. :: 24-07-1985 :: 03-10-1984 :: Fisons Corporation :: 755 Jefferson Rd. :: P.O. Box 1710 :: Rochester NY 14603

Chenodiol :: Chenix :: For patients with radiolucent stones in well opacifying gallbladders, in whom elective surgery would be undertaken except for the presence of increased surgical risk due to systemic disease or age. :: 21-09-1984 :: 28-07-1983 :: Solvay :: 901 Sawyer Road :: Marietta GA 30062

Hemin :: Panhematin :: Amelioration of recurrent attacks of acute intermittent porphyria (AIP) temporarily related to the menstrual cycle in susceptible women and similar symptoms which occur in other patients with AIP, porphyria variegata and hereditary coproporphyria. :: 16-03-1984 :: 20-07-1983 :: Abbott Laboratories :: Diagnostics Division :: Abbott Park IL 60064

(+/-)-7-[3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy]-3,4-dihydro-8-propyl-2H-1-benzopyran-2-carboxylic acid :: Prevention of serious adverse events associated with vascular leak syndrome caused by Interleukin-2 therapy :: 31-03-2003 :: Intarcia Therapeutics, Inc. :: 24650 Industrial Blvd :: Hayward CA 94545

(+/-)-cis-3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-3,4-dihydro-2H-cromen-7-ol :: Treatment of Stage IIB through Stage IV malignant melanoma :: 01-02-2008 :: Marshall Edwards, Inc. :: 140 Wicks Road :: AUSTRALIA

(+/-)-cis-3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-3,4-dihydro-2H-cromen-7-ol :: Treatment of pancreatic cancer :: 10-01-2008 :: Marshal Edwards, Inc. :: 140 Wicks Road :: AUSTRALIA

(+/-)-cis-3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-3,4-dihydro-2H-cromen-7-ol :: Treatment of cholangiocarcinoma :: 10-01-2008 :: Marshall Edwards, Inc. :: 140 Wicks Road :: AUSTRALIA

(1R,2R)-Octanoic acid [2-(2',3'-dihydrobenzo[1,4]dioxin-6'-yl)-2-hydroxy-l-pyrrolidin-1-ylmethyl-ethyl]-amide-L-tartaric acid salt :: Treatment of Gaucher disease :: 17-09-2008 :: Genzyme Corporation :: 500 Kendall Street :: Cambridge MA 02142

(1R,2S) 6-bromo-alpha-[2-(dimethylamino)ethyl]-2-methoxy-alpha-(1-naphthyl)-beta-phenyl-3-quinolineethanol :: Treatment of pulmonary tuberculosis (active disease) :: 10-01-2005 :: Tibotec, Inc. :: 1020 Stony Hill Road :: Yardley PA 19067

(1S)-1-(9-deazahypoxanthin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol-hydrochloride :: Treatment of chronic lymphocytic leukemia and related leukemias to include prolymphocytic leukemia, adult T-cell leukemia, and hairy cell leukemia :: 10-08-2004 :: BioCryst Pharmaceuticals, Inc. :: 2190 Parkway Lake Drive :: Birmingham AL 35244

(1S)-1-(9-deazahypoxanthin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol-hydrochloride :: Treatment of acute lymphoblastic leukemia :: 13-08-2004 :: BioCryst Pharmaceuticals, Inc. :: 2190 Parkway Lake Drive :: Birmingham AL 35244

(1S)-1-(9-deazahypoxanthin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol-hydrochloride :: Treatment of T-cell non-Hodgkin's lymphoma :: 29-01-2004 :: BioCryst Pharmaceuticals, Inc. :: 2190 Parkway Lake Drive :: Birmingham AL 35244

(2Z)-2-cyano-3-3hydroxy-N-[4-(trifluoromethly)phenyl]-2-hepten-6-ynamide :: FK778 :: Prevention of acute rejection following kidney, heart, and liver tranplantation :: 10-01-2005 :: Fujisawa Healthcare, Inc. :: Three Parkway North :: Deerfield IL 60015-2548

(3S)-3-(4-trifluoromethoxybenzyloxy)-6-nitro-2H-3,4-dihydroimidazo[2,1-b]oxazine :: Treatment of tuberculosis. :: 05-07-2007 :: Global Alliance for TB Drug Development :: 80 Broad Street :: New York NY 10004

(3S)-3-[(2S)-2-({N-[2-tert-butyl)phenyl]carbamoyl}carbonylamino) propanoylamino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy) pentanoci acid :: Treatment of patients undergoing solid organ transplantation. :: 19-08-2003 :: Pfizer Global Research and Development :: 50 Pequot Avenue :: New London CT 06320

(4S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1-H-pyrano[3?,4?:6,7]-indolizino-[1,2-b]-quinoline-11-carbaldehyde O-(tert-butyl)-(E)-oxime :: Gimatecan :: Treatment malignant glioma :: 29-11-2002 :: Sigma-Tau Research, Inc. :: 9841 Washingtonian Blvd :: Suite 502 :: Gaithersburg MD 20878

(6R,S)5,10-methylene-tetrahydrofolic acid :: CoFactor :: For use in combination with 5-fluorouracil for the treatment of patients with pancreatic cancer :: 13-08-2004 :: Adventrx Pharmaceuticals, Inc. :: 6725 Mesa Ridge Road :: Suite 100 :: San Diego CA 92121

(9-[N-(3-morpholinopropyl)-sulfonyl]-5,6-dihydro-5-oxo-11-H-indeno [1,2-c] isoquinoline methanesulfonic acid :: Prevention of post-operative complications of aortic anuerysm surgical repair :: 08-12-2004 :: Inotek Pharmaceuticals Corporation :: 100 Cummings Center :: Beverly MA 01915

(R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo[2,1-b]oxazole :: Treatment of pulmonary tuberculosis. :: 12-07-2007 :: Otsuka Pharmaceutical Company, Ltd :: 2440 Research Blvd :: Rockville MD 20850

(R)-4-(3-morpholin-4-yl-1-phenylsulfanylmethyl-propylamino)-N-(4-{4-[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-enylmethyl]-piperazin-1-yl}-benzoyl)-3-trifluoromethanesulfonylbenzenesulfonamide bis-hydrochloride :: Treatment of small cell lung cancer :: 19-12-2007 :: Abbott Laboratories :: 200 Abbott Park Road :: AP34/RA72 :: Abbott Park IL 60064-6188

(R)-4-(3-morpholin-4-yl-1-phenylsulfanylmethyl-propylamino)-N-(4-{4-[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-enylmethyl]-piperazin-1-yl}-benzoyl)-3-trifluoromethanesulfonylbenzenesulfonamide bis-hydrochloride :: Treatment of multiple myeloma :: 05-05-2008 :: Abbott Laboratories :: 200 Abbott Park Road :: Abbott Park IL 60064

(R)-4-(3-morpholin-4-yl-l-phenylsulfanylmenthyl-propylamino)-N-(4-{4-[2-(4-chlorophenyl)-5,5-dimethylcyclohex-l-enylmethyl]-piperazin-l-yl}-benzoyl)-3-trifluoromethanesulfonylbenzenesulfonamide bis-hydrochloride :: Treatment of chronic lymphocytic leukemia :: 19-12-2007 :: Abbott Laboratories :: 200 Abbaott Park Road :: AP34/RA72 :: Abbott Park IL 60064-6188

(R)-N-[2-(6-chloro-5-methoxy-1H-indol-3-yl)propyl]acetamide :: Treatment of circadian rhythm sleep disorders in blind people with no light perception :: 03-10-2001 :: Phase 2 Discovery, Inc. :: 3130 Highland Avenue, Third Floor :: Cincinnati OH 45219-2374

(R)-N-[2-(6-Chloro-methoxy-1H-indol-3yl)propyl]acetamide :: Treatment of neuroleptic-induced tardive dyskinesia in schizophrenia patients :: 03-07-2003 :: Phase 2 Discovery, Inc. :: 3130 Highland Ave. :: Third Floor :: Cincinnati OH 45219

(s)-3'-(HO)-DADFT-PE :: Treatment of chronic iron overload in patients with transfusion-dependent anemias :: 04-02-2009 :: Ferrokin BioSciences, Inc. :: 2729 Debbie Court :: San Carlos CA 94070

(UDU-stereoisomer of c-UJUun UNU-terminal UkUnhibitor) :: Treatment of acute sensorineural hearing loss :: 28-03-2006 :: Auris Medical, Inc. :: 211 East Ontario Street :: Chicago IL 60611

(Z-8-methyl-N-vanillyl-6-nonnamide) ; Civamide :: Treatment of postherpetic neuralgia. :: 17-02-2009 :: Winston Laboratories, Inc. :: 100 Fairway Drive :: Vernon Hills IL 60061

[131I]-N-(2-(diethylamino) ethyl-4-(4 flurobenzamido)-5-(iodo)-2-methoxybenzamide :: Treatment of metastatic melanoma, stages IIB, IIC, III and IV :: 17-09-2008 :: Molecular Insight Pharmaceuticals, Inc. :: 160 Second Street :: Cambridge MA 02142

[5,10,15,20-tetrakis(1,3-diethylimidazolium-2-yl)porphyrinato] manganese(III)pentachloride :: Treatment of Amyotrophic Lateral Sclerosis :: 04-11-2003 :: Aeolus Pharmaceuticals, Inc. :: PO Box 14287; 79 T.W. Alexander Dr. :: 4401 Research :: Research Triangle Park NC 27709

[Lu-177]-DOTA-Tyr3-Octreotate :: Treatment of gastro-entero-pancreatic neuroendocrine tumors :: 12-01-2009 :: BioSynthema, Inc. :: 4041 Forest Park Avenue :: St. Louis MO 63108

[Nle4, D-Phe7]-a-melanocyte stimulating hormone :: Treatment of erythropoietic porphyrias :: 17-07-2008 :: Clinuvel Inc. :: 353 Sacramento Street :: San Francisco CA 94111

1,5-(Butylimino)-1,5 dideoxy,D-glucitol :: Treatment of Fabry's disease. :: 12-05-1998 :: Oxford GlycoSciences :: 10, The Quadrant :: Abington Science Park :: United Kingdom :: UNITED KINGDOM

11-(2-Pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.12,6.18,12}heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene :: For treatment of myeloproliferative disorders (MPD) with the JAK2 V617F mutation. :: 13-03-2008 :: S*BIO Pte., Ltd. :: 1 Science Park Road :: Singapore Science Park II :: SINGAPORE

111Indium pentetreotide :: SomatoTher :: Treatment of somatostatin receptor positive neuroendocrine tumors. :: 10-06-1999 :: Louisiana State University Medical Center Foundation :: 1600 Canal St. :: 10th Floor :: New Orleans LA 70112

166Ho-DOTMP :: Treatment of multiple myeloma. :: 10-02-1999 :: NeoRx Corporation :: 410 W. Harrison Street :: Seattle WA 98119-4007

17 a-Hydroxyprogesterone caproate :: Gestiva :: Prevention of preterm birth in singleton pregnancies :: 25-01-2007 :: Hologic, Inc. :: 1240 Elko Drive :: Sunnyvale CA 94089

17-allylamino-17-demethoxygeldanamycin (17-AGG) :: For the treatment of chronic myelogenous leukemia. :: 03-09-2004 :: Bristol-Myers Squibb Company :: Research & Development :: 5 Research Parkway :: Wallingford CT 06492-7660

1-Deoxygalactonojirimycin :: Treatment of Fabry Disease :: 25-02-2004 :: Amicus Therapeutics, Inc. :: 6 Cedar Brook Drive :: Cranbury NJ 08512

1-dexynojirimycin hydrochloride :: Treatment of Pompe disease :: 18-06-2007 :: Amicus Therapeutics, Inc :: 6 Cedar Brook Drive :: Cranbury NJ 08512

2 dimethylbutyrate :: Treatment of beta thalassemia :: 18-06-2008 :: HemaQuest Pharmaceuticals, Inc. :: 101 Federal Street :: Boston MA 02110

2-(2-phenylvinyl)-4-[4-methylpiperazin-l-yl)]-6-(5-methyl-2H-pyrazol-3-yl-amino)-pyrimidine L(+) tartrate salt :: Treatment of multiple myeloma. :: 22-12-2008 :: EntreMed, Inc. :: 9640 Medical Center Drive :: Rockville MD 20850

2-(2-phenylvinyl)-4-[4-methylpiperazin-l-yl)]-6-(5-methyl-2H-pyrazol-3-ylamino)-pyrimidine L(+) tartrate salt :: Treatment of ovarian carcinoma :: 18-03-2009 :: EntreMed, Inc. :: Research Triangle Park Center :: Suite 400 :: Durham NC 27703

2-(3,5-dichloro-phenyl)-benzoxazole-6-carboxylic acid :: Treatment of familial amyloid polyneuropathy :: 23-05-2006 :: FoldRx Pharmaceuticals, Inc. :: 300 Technology Square :: Cambridge MA 02139

2-(3-diethylaminopropyl)-8,8-dipropyl-2-azaspiro [4,5] decan dimaleate :: Atiprimod :: Treatment of mulitple myeloma and associated bone resorption :: 02-12-2003 :: Callisto Pharmaceuticals, Inc. :: 2 Executive Drive :: Suite 450 :: Somerset NJ 08873

2-(3-Diethylaminopropyl)-8,8-dipropyl-2-azaspiro[4,5] decane dimaleate :: Atiprimod :: Treatment of carcinoid tumors :: 18-09-2006 :: Callisto Pharmaceuticals, Inc. :: 420 Lexington Avenue :: New York NY 10170

2',3',5'-tri-o-acetyluridine :: Treatment of mitochondrial disease :: 13-01-2003 :: Repligen Corporation :: 41 Seyon Street :: Building 1, Suite 100 :: Waltham MA 02453

2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, dihydrochloride, monohydrate, (6R)-; (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazolediamine dihydrochloride monohydrate :: Treatment of amyothrophic lateral sclerosis (ALS). :: 11-10-2007 :: Knopp Neurosciences, Inc. :: 2100 Wharton Street :: Pittsburgh PA 15203

2-[(3-methyl-4-(2,2,2-trifluoroethoxy) pyridin-2-yl)methylsulfinyl] -1H-benzoimidazole :: PreVonco ™ :: Treatment of hepatocellular carcinoma. :: 27-08-2008 :: BioQuant, Inc. :: 6330 Nancy Ridge Drive :: San Diego CA 92121

2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimadazole-4-carboxamide :: Treatment of malignant melanoma stages IIb through IV. :: 18-12-2007 :: Abbott Laboratories :: Global Pharmaceutical Research and Development :: 200 Abbott Park Road :: Abbott Park IL 60064-6157

2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimadazole-4-carboxamide :: Treatment glioblastoma multiforme when used in combination with DNA-damaging agents :: 09-05-2008 :: Abbott Laboratories :: Global Pharmaceutical Research and Development :: Abbott Park IL 60064

2-0-Butyryl-1-0-octyl-myo-inositol 3,4,5,6-tetrakisphosphate :: Treatment of cystic fibrosis :: 15-08-2003 :: Inologic, Inc. :: 101 Elliott Ave., West :: Seattle WA 98119

2-0-desulfated heparin :: Aeropin :: Treatment of cystic fibrosis. :: 17-09-1993 :: Kennedy & Hoidal, M.D.'s :: University of Utah Health Sciences Center :: 50 North Medical Drive, Room 4R240 :: Salt Lake City UT 84132

20-mer complementary to Akt mRNA :: Treatment of stomach cancer :: 10-12-2004 :: Rexahn Corporation :: 9620 Medical center Drive :: Rockville MD 20850

20-mer oligonucleotide complementary to Akt mRNA :: Treatment of pancreatic cancer :: 08-12-2004 :: Rexahn Corporation :: 9620 Medical Center Drive :: Rockville MD 20850

20-mer oligonucleotide complementary to Akt mRNA :: Treatment of glioblastoma :: 08-12-2004 :: Rexahn Corporation :: 9620 Medical center Drive :: Rockville MD 20850

20-mer oligonucleotide complementary to Akt mRNA :: Treatment of renal cell carcinoma :: 01-12-2004 :: Rexahn Corporation :: 9620 Medical Center Drive :: Rockville MD 20850

20-mer oligonucleotide complementary to Akt mRNA :: Treatment of ovarian cancer :: 01-12-2004 :: Rexahn Corporation :: 9620 Medical Center Drive :: Rockville MD 20850

2'-3'-dideoxyadenosine :: Treatment of aquired immunodeficiency syndrome. :: 21-07-1987 :: National Cancer Institute, Dct :: NIH, Exec. Plaza N., Room 7-18 :: Bethesda MD 20892

24,25 dihydroxycholecalciferol :: Treatment of uremic osteodystrophy. :: 27-02-1987 :: Lemmon Company :: 1510 Delp Drive :: Kulpsville PA 19443

2-chloroethyl-3-sarcosinamide-1-nitrosourea :: Treatment for malignant gliomas :: 03-08-2001 :: Lawrence Panasci, MD :: Professor of Medicine, McGill University :: 3755 Cote Ste Catherine :: Montreal, Quebec H3T 1E2 :: CANADA

2-chloroethyl-3-sarcosinamide-1-nitrosourea :: Sarmustine :: Treatment for malignant glioma :: 15-11-2001 :: Pangene Corporation :: 5500 Stewart Avenue :: Fremont CA 94538

2'-deoxycytidine :: As a host-protective agent in the treatment of acute myelogenous leukemia. :: 09-09-1996 :: Grant, Steven M.D. :: Massey Cancer Center, VCU :: P.O. Box 980230 :: Richmond VA 23298-0230

2-iminobiotin :: Treatment of perinatal asphyxia. :: 24-02-2009 :: Neurophyxia B.V. :: Onderwijsboulevard 219 :: NETHERLANDS

2-methoxyestradiol :: PulmoLAR :: Treatment of pulmonary arterial hypertension :: 11-04-2005 :: PR Pharmaceuticals, Inc. :: 1716 Heath Parkway :: Fort Collins CO 80524

2-methoxyestradiol :: Panzem NCD :: Treatment of ovarian cancer :: 04-04-2005 :: EntreMed, Inc. :: 9640 Medical Center Drive :: Rockville MD 20850

2-methoxyestradiol :: Panzem :: Treatment of multiforme glioblastoma :: 16-06-2006 :: EntreMed, Inc. :: 9640 Medical Center Drive :: Rockville MD 20850

2-methoxyestradiol :: Panzem :: Treatment of multiple myeloma :: 10-07-2001 :: EntreMed, Inc. :: 9640 Medical Center Drive :: Rockville MD 20850

2'-O-methyl-phosphorothiolate oliogribonucleotide :: Treatment of Duchenne muscular dystrophy :: 18-11-2005 :: Prosena B.V. :: Einsteinweg 55 :: NETHERLANDS

3-(3,5-Dimethyl-1H-2ylmethylene)-1,3-dihydro-indol-2-one :: Treatment of von Hippel-Lindau disease. :: 23-03-2000 :: Sugen, Inc. :: 230 East Grand Ave. :: South San Francisco CA 94080

3-(3,5-dimethyl-1H-2ylmethylene)-1,3-dihydro-indol-2-one :: Treatment of Kaposi's sarcoma. :: 11-09-1998 :: Sugen, Inc. :: 230 East Grand Ave. :: South San Francisco CA 94080-4811

3,4-diaminopyridine :: Treatment of Lambert-Eaton myasthenic syndrome. :: 18-12-1990 :: Jacobus Pharmaceutical Company :: 37 Cleveland Avenue :: P.O. Box 5290 :: Princeton NJ 08540

3,5,3'-triiodothyroacetate :: Treatment of well-differentiated papillary, follicular or combined papillary/follicular carcinomas of the thyroid gland. :: 20-09-2000 :: Elliot Danforth, Jr., M.D. :: University of Vermont :: 84 Beartown Road :: Underhill VT 05489

3-[5-(2-fluoro-plhenyl)-[1,2,4]oxadiazole-3-yl]benzoic acid :: Treatment of Muscular Dystrophy resulting from premature stop mutations in the dystrohin gene :: 10-01-2005 :: PTC Therapeutics, Inc. :: 100 Corporate Court :: South Plainfield NJ 07080

3-[5-(2-fluoro-plhenyl)-[1,2,4]oxadiazole-3-yl]benzoic acid :: For use in the treatment of cystic fibrosis resulting fron a nonsense (premature stopcodon) mutation in the cystic bibrosis transmembrane conductance regulatory gene. :: 01-09-2004 :: PTC Therapeutics :: 100 Corporate Court :: South Plainfield NJ 07080

3-[5-(2-fluoro-plhenyl)-[1,2,4]oxadiazole-3-yl]benzoic acid :: Treatment of spinal muscular atrophy. :: 10-03-2008 :: PTC Therapeutics, Inc. :: 100 Corporate Court :: South Plainfield NJ 07080

3'-azido-2',3'dideoxyuridine :: AZDU :: Treatment of acquired immunodeficiency syndrome. :: 20-11-1989 :: Berlex Laboratories, Inc. :: 1401 Harbor Bay Parkway :: Alameda CA 94501

3-fluoro-5-[5-(2-menthyl-thiazol-4-ylethylnyl)-pyridin-2-yl]-benzonitrile dihydrochloride :: Treatment of behavioral abnormalities associated with fragile X syndrome. :: 28-07-2008 :: Seaside Therapeutics :: 840 Memorial Drive :: Cambridge MA 02139

4-(2-fluorophenyl)-6-methyl-2-(1-piperzinyl) :: Treatment of Chronic Functional Vomiting to include functional vomiting and cyclic vomiting syndrome. :: 11-10-2006 :: Dynogen Pharmaceuticals, Inc. :: 52 Second Avenue :: Waltham MA 02451

4-(3-Methanesulfonyl-phenyl)-1-propylpiperidine HCl :: Treatment of Huntington disease. :: 12-12-2005 :: NeuroSearch Sweden AB :: Scerige :: Pederstrupvej 93 :: SWEDEN

4, 5 dibromorhodamine methyl ester :: Theralux Photodynamic Therapy :: Treatment of follicular lymphoma :: 30-10-2008 :: Kiadis Pharma Canada, Inc. :: 2525 Marie Curie :: Canada H4S 2E1 :: CANADA

4, 5 dibromorhodamine methyl ester :: Theralux Photodynamic Therapy :: Treatment of diffuse large B-cell lymphoma :: 30-10-2008 :: Kiadis Pharma Canada, Inc. :: 2525 Marie Curie :: CANADA

4,5 dibromorhodamine methyl ester :: Theralux Photodynamic Therapy :: For immune reconstitution and prevention of graft versus host disease following allogeneic hematopoietic stem cell transplantation. :: 23-10-2007 :: Kiadis Pharma Canada, Inc. :: 2525 Marie Curie :: Canada H4S 2E1 :: CANADA

4,5-dibromorhodamine 123 :: Theralux Irradiation Device :: Treatment of chronic myelogenous leukemia :: 10-04-2003 :: Kiadis Pharma Canada, Inc. :: 2525 Marie-Curie :: Saint-Laurent (Quebec) H4S 2E1 :: CANADA

4,6,8-trihydroxy-10-(3,7,11-trimethyldodeca-2,6,10-trienyl)-5,10-dihydrodibenzo b,e][1,4]diazepin-11-one :: Treatment of malignanat glioma :: 27-04-2009 :: Thallion Pharmaceuticals, Inc. :: 7150 Alexander-Fleming :: CANADA

4-[[[4-(4-Chlorophenoxy)phenyl]sulfonyl]-methyl] tetrahydro-N-hydroxy-2H-pyran-4-carboxamide :: Prophylaxis of organ rejection in patients receiving allogeneic liver transplants :: 18-06-2008 :: Conatus Pharmaceuticals, Inc. :: 4365 Executive Drive :: San Diego CA 921214-[1]benzofuro[3,2-d]pyrimidin-4-yl-N-(1,3-benzodioxol-5-ylmethyl)piperazine-1-carbothioamide :: Treatment, in combination with radiotherapy and temozolomide chemotherapy, of patients with glioblastoma multiforme. :: 30-07-2008 :: SuperGen, Inc. :: 4140 Dublin Blvd :: Dublin CA 9456840SD02 :: Treatment of chronic iron overload resulting from conventional transfusional treatment of beta-thalassemia major and sickle cell anemia. :: 21-12-1998 :: Biomedical Frontiers, Inc. :: 1095 10th Ave., S.E. :: Minneapolis MN 554144-Amino-1-[5-O-[(2R, 4S)-2-oxido-4-(4-pyridinyl)-1, 3, 2-dioxaphosphorinan-2-yl]-b-D-arabinofuranosyl]-2(1H)-pyrimidinone :: Treatment of hepatocellular carcinoma. :: 22-08-2007 :: Metabasis Therapeutics, Incorporated :: 11119 North Torrey Pines Road :: LaJolla CA 920374-Aminopyridine :: Treatment chronic functional motor and sensory deficits from Guillain-Barre syndrome :: 14-12-2005 :: Acorda Therapeutics, Inc. :: 15 Skyline Drive :: Hawthorne NY 105324-aminosalicylic acid :: Paser Granules :: Treatment of acute flares in pediatric patients with ileo-cecal Crohn's disease :: 26-04-2006 :: Jacobus Pharmaceutical Co., Inc. :: 37 Cleveland Lane :: Princeton NJ 085404-aminosalicylic acid :: Pamisyl (P-D), Rezipas (Squibb) :: Treatment of mild to moderate ulcerative colitis in patients intolerant to sulfasalazine. :: 13-12-1989 :: Beeken, Warren M.D. :: University Of Vermont :: Given C-317 :: Burlington VT 05405 4-cholest-en-3-one, oxime :: Treatment of amyotrophic lateral sclerosis :: 01-12-2005 :: Trophos SA :: Parc scientifique de Lumigny, Case 931 :: 1322 Marseille cedex :: FRANCE4-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide monohydrochloride :: Treatment of acute myeloid leukemia :: 20-07-2006 :: Johnson & Johnson Pharmaceutical Research & Dev, :: 920 U S Highway 202 :: P.O. Box 300 :: Raritan NJ 08869 4-trifluoromethyl-N-(3.3a.4.4a.5,5a,6,6a-octahydro-1,3-dioxo-4,6ethenocycloprop[f]isoindol-2(1H)-yl)-benzamide :: Treatment of smallpox. :: 27-12-2006 :: SIGA Technologies, Inc. :: 4575 SW Research Way :: Suite 230 :: Corvallis OR 97333 4-trifluoromethyl-N-(3.3a.4.4a.5,5a,6,6a-octahydro-1,3-dioxo-4,6ethenocycloprop[f]isoindol-2(1H)-yl)-benzamide :: post exposure prophylaxis against smallpox :: 18-12-2006 :: SIGA Technologies, Inc. :: 4575 SW Research Way :: Suite 230 :: Corvallis OR 97333 5(S)-(2'-hydroxy ethoxy)-20(S)-Camptothecin :: Treatment of osteosarcoma (bone cancer) :: 15-06-2007 :: ClinTec International Ltd./Caledonia Pharma Ltd. :: Guerickestrasse 25 :: 80805 Munich, :: GERMANY5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-(phenylmethyl)-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S,10S)- (9CI) :: Treatment of malignant gliomas :: 11-10-2006 :: Reata Pharmaceuticals, Inc. :: 1950 N. Stemmons Freeway :: Dallas TX 75207-3199 5,5',5"-[Phosphinothioylidyne-tris(imino-2,1-ethanediyl)]tris[5-methylchelidoninium]trihydroide hexahydrochloride :: Treatment of pancreatic cancer :: 20-08-2003 :: Now Pharm AG :: 241, route d'Arlon :: L-1150 :: LUXEMBOURG5,6-dihydro-5-azacytidine :: Treatment of malignant mesothelioma. :: 11-05-1992 :: ILEX Oncology, Inc. :: 4545 Horizon Hill Blvd. :: San Antonio TX 78229-2263 5,7-dihydroxy-3-(4-hydroxyphenyl)-chromen-4-one :: Prevention of acute radiation syndrome :: 18-06-2007 :: Humanetics, Inc. :: 10400 Viking Drive :: Eden Prairie MN 553445-[(E)-2-(4-hydroxyphenyl)-ethenyl] benzene-1,3 diol :: Resveratrol :: Treatment of MELAS syndrome :: 13-03-2008 :: Sirtris Pharmaceuticals, Inc. :: 200 Technology Square :: Cambridge MA 02139506U78 :: Treatment of chronic lymphocytic leukemia. :: 02-09-1999 :: GlaxoSmithKline :: Five Moore Dr. :: P.O. Box 13398 :: Research Triangle Park NC 27709-33985a8, monoclonal antibody to CD4 :: For use in post-exposure prophylaxis for occupational exposure to human immunodeficiency virus. :: 20-12-1993 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 021425-aza-2'-deoxycytidine :: Treatment of acute leukemia. :: 03-08-1987 :: SuperGen, Inc. :: 4140 Dublin Blvd. :: Suite 200 :: Dublin CA 94568 5-Azacitidine :: Vidaza :: Treatment of acute myeloid leukemia :: 18-06-2008 :: Celgene Corporation :: 9900 W. 109th Street :: Suite 300 :: Overland Park KS 66210 5-hydroxymethyl-2-furfuraldehyde :: Treatment of sickle cell disease :: 26-05-2006 :: Xechem International, Inc. :: New Brunswick Technoloogy Center :: Building 1, Suite 310 :: New Brunswick NJ 08901-32795-iodo-2-pytimidinone-2'-deoxyribose :: Treatment of malginant glioma :: 26-05-2006 :: Hana Biosciences, Inc. :: 7000 Shoreline Court :: Suite 370 :: South San Francisco CA 94080 5-methyl-1-phenyl-2-(1H)-pyridone(CAS 53179-13-8) :: Pirfenidone :: Treatment of idiopathic pulmonary fibrosis :: 05-03-2004 :: InterMune, Inc. :: 3280 Bayshore Blvd :: Brisbane CA 940055'-O-(trans-9"-octadecenoyl)-1-B-D-arabinofuranosyl cytosine :: Treatment of acute myeloid leukemia. :: 18-06-2008 :: Clavis Pharma ASA :: Parkveien 53 B :: NORWAY6 alpha-ethylchenodeoxycholic acid :: Treatment of primary biliary cirrhosis :: 09-04-2008 :: Intercept Pharmaceuticals, Inc. :: 18 Desbrosses Street :: New York NY 100136,8-bis-benzylsulfanyl-octanoic acid :: Treatment of pancreatic cancer :: 06-02-2006 :: Cornerstone Pharmaceuticals, Inc. :: 25 Health Science Drive :: Stony Brook NY 117906-alpha-ethylchenodeoxycholic acid :: Treatment of primary sclerosing cholangitis :: 09-04-2008 :: Intercept Pharmaceuticals, Inc. :: 18 Desbrosses Street :: New York NY 100136-hydroxymethylacylfulvene :: Treatment of histologically confirmed advanced or metastatic pancreatic cancer. :: 06-04-1999 :: Eisai Medical Research, Inc. :: 55 Challenger Road :: Ridgefield Park NJ 076608-methoxsalen :: Uvadex :: For use in conjunction with the UVAR photopheresis to treat diffuse systemic sclerosis. :: 22-06-1993 :: Therakos, Inc. :: Oaklands Corporate Center :: 437 Creamery Way :: Exton PA 19341 8-methoxsalen :: Uvadex :: For the prevention of acute rejection of cardiac allografts. :: 12-05-1994 :: Therakos, Inc. :: Oaklands Corporate Center :: 437 Creamery Way :: Exton PA 19341 90Y-hPAMA4 :: PAN-Cide :: Treatment of pancreatic cancer :: 29-01-2004 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 079509-cis-retinoic acid :: Prevention of retinal detachment due to proliferative vitreoretinopathy. :: 02-01-1997 :: Allergan, Inc. :: 2525 Dupont Drive :: P.O. Box 19534 :: Irvine CA 92623-95349-nitro-20-(S)-camptothecin :: Treatment of pancreatic cancer. :: 16-09-1996 :: SuperGen, Inc. :: 4140 Dublin Blvd. :: Suite 200 :: Dublin CA 94568 9-nitro-20-(S)-camptothecin :: Camvirex :: Treatment of pediatric HIV infection/AIDS :: Treatment of pediatric HIV-infection/AIDS patients :: 15-05-2001 :: NovoMed Pharmaceuticals, Inc. :: P.O. Box 900 :: Germantown MD 20875-0900 a-(3-aminophthalimido) glutaramide :: Actimid :: Treatment of multiple myeloma :: 15-01-2003 :: Celgene Corporation :: 7 Powder Horn Drive :: Warren NJ 07059 A10 & AS2-1 Antineoplaston :: Treatment for patients with brain stem glioma :: 03-09-2004 :: Burzynski Research Institute, Inc. :: 9432 Old Katy Road :: Houston TX 77055AAV2-hRPE65v2 :: Treatment of Leber congenital amaurosis due to RPE65 mutations. :: 24-06-2008 :: Center for Cellular & Molecular Therapeutics :: The Children's Hospital of Philadelphia :: Philadelphia PA 19104Abetimus :: Treatment of lupus nephritis. :: 28-07-2000 :: La Jolla Pharmaceutical Co. :: 6455 Nancy Ridge Dr. :: San Diego CA 92121ACA125 :: Treatment of epithelial ovarian cancer :: 25-11-2003 :: Menarini Ricerche S.p.A. :: Via Tito Speri 10 :: Pomezia Roma :: ITALYAcetylcysteine :: Mucomyst/Mucomyst 10 IV :: Intravenous treatment of patients presenting with moderate to severe acetaminophen overdose. :: 13-08-1987 :: Bristol-Myers Squibb Company :: P.O. Box 4500 :: Princeton NJ 08543-4500 Acid sphingomyelinase :: Treatment of acid sphingomyelinase deficiency (Niemann-Pick disease). :: 03-08-2000 :: Genzyme Corporation :: 500 Kendall Street :: Cambridge MA 02142Adalimumab :: Humira :: Treatment of pediatric Crohn's disease. :: 19-10-2006 :: Abbott Laboratories :: 200 Abbott Park Road :: Abbott Park IL 60064-6188 Adeno-associated vector expressing the human lipoprotein lipase protein :: Treatment of lipoprotein lipase deficiency :: 21-05-2007 :: Amsterdam Molecular Therapeutics BV :: P. O. Box 22506 :: NETHERLANDSAdeno-associated viral vector containing the gene for human coagulation factor IX :: Coagulin-B :: Intramuscular treatment of patients with moderate to severe hemophilia :: 13-06-2001 :: Avigen, Inc. :: 1301 Harbor Bay Parkway :: Alameda CA 94502Adeno-associated viral vector containing the gene for human coagulation factor IX :: Coagulin-B :: Intrahepatic treatment of patients with moderate to severe hemophilia :: 13-06-2001 :: Avigen, Inc. :: 1301 Harbor Bay Parkway :: Alameda CA 94502Adeno-associated viral vector expressing human acid alpha glucosidase gene :: Treatment of Pompe disease :: 20-03-2007 :: Applied Genetic Technologies Corporation :: 11801 Research Drive :: Alachua FL 32615adeno-associated viral vector expressing human retinoschisin-1 gene :: Treatment of X-linked juvenile retinoschisis (XLRS). :: 21-05-2007 :: Applied Genetic Technologies Corporation :: 11801 Research Drive :: Alachua FL 32615Adeno-associated viral vector serotype 5 containing human ABCA4 gene :: Treatment of Stargardt's disease. :: 30-09-2008 :: Fondazione Telethon :: Via Guglielmo Saliceto, 5/a :: ITALYAdeno-associated viral-based vector cystic fibrosis gene therapy :: Treatment of cystic fibrosis. :: 15-02-1995 :: Targeted Genetics Corporation :: 1100 Olive Way, Suite 100 :: Seattle WA 98101Adenosine :: For use in conjunction with BCNU in the treatment of brain tumors. :: 01-08-1989 :: Medco Research, Inc. :: 8455 Beverly Boulevard :: Suite 308 :: Los Angeles CA 90048 Adenoviral vector expressing Herpes simplex virus thymidine kinase gene :: Treatment of malignant brain tumors :: 17-06-2005 :: Advantagene, Inc. :: 160 Paulson Road :: Waban MA 02468Adenovirus-based vector Factor VIII complementary DNA to somatic cells :: MiniAdFVIII :: Treatment of hemophilia A. :: 15-12-1999 :: GenStar Therapeutics Corporation :: 10835 Altman Row :: Suite 150 :: San Diego CA 92121 adenovirus-mediated herpes simplex virus-thymidine kinase gene :: Use with gancyclovir in the treatment of malignant glioma :: 31-07-2001 :: Ark Therapeutics Ltd :: 6 Warren Mews :: London W1T6AR :: London :: UNITED KINGDOMAerosolized pooled immune globulin :: Treatment of respiratory syncytial virus lower respiratory tract disease. :: 03-01-1989 :: Pediatric Pharmaceuticals, Inc. :: 718 Bradford Avenue :: Westfield NJ 07090a-Galactosidase A :: Plant-Produced Human a-Glactosidase A :: Treatment of Fabry's disease :: 21-01-2003 :: Alpha Gal, LLC :: a Kentucky Bioprocessing (KBP) subsidiary :: 3700 Airpark Drive :: Owensboro KY 42301 Aglycosyl anti-CD3 monoclonal antibody :: Treatment of new-onset type I diabetes mellitus :: 06-02-2006 :: TolerRX, Inc. :: 300 Technology Square :: Cambridge MA 02139AI-RSA :: Treatment of autoimmune uveitis. :: 08-10-1992 :: AutoImmune, Inc. :: 128 Spring Street :: Lexington MA 02173Albuterol :: Prevention of paralysis due to spinal cord injury :: 12-03-2002 :: MotoGen, Inc. :: 3 Pine View Road :: Mount Kisco NY 10549ALD-101 :: To improve patient outcomes by decreasing time to platlet and neutrophil engraftment in patients with inherited metabolic diseases (IMD) undergoing umbilical cord blood transplantation. :: 23-10-2008 :: Aldagen, Inc. :: 2810 Meridian Parkway :: Durham NC 27713Aldesleukin :: Proleukin :: Treatment of primary immunodeficiency disease associated with T-cell defects. :: 22-03-1989 :: Chiron Corporation :: 4560 Horton Street :: Emeryville CA 94608-2916 Aldesleukin :: Proleukin :: Treatment of acute myelogenous leukemia. :: 31-07-1998 :: Chiron Corporation :: 4560 Horton St. :: Emeryville CA 94608-2916 Aldesleukin :: Proleukin :: For the treatment non-Hodgkin's lymphoma. :: 24-11-1998 :: Chiron Corporation :: 4560 Horton St. :: Emeryville CA 94608-2916 Alefacept :: Amevive :: For use as prophylaxis of rejection in patients receiving allogenic solid organ transplants. :: 19-12-2007 :: Astellas Pharma US, Inc. :: Three Parkway North :: Deerfield IL 60015-2548 alendronate :: Fosamax :: Treatment of osteogenesis imperfecta in pediatric patients 4 years of age and older :: 31-03-2003 :: Merck & Co., Inc. :: 126 East Lincoln Ave. :: Rahway NJ 07065-0900 Alendronate disodium :: Fosamax :: Treatment of the bone manifestations of Gaucher disease :: 13-02-2001 :: Richard J. Wenstrup, M.D. :: Division of Human Genetics :: Children's Hospital Research Foundation :: Cincinnati OH 45229-3039Alfentanil :: Management of postherpetic neuralgia :: 08-07-2005 :: Cinergen, LLC :: 146 Medinah Drive :: Blue Bell PA 19422-3212 Alfentanil :: Treatment of painful HIV-associated neuropathy :: 09-08-2005 :: Cinergen, LLC :: 146 Medinah Drive :: Blue Bell PA 19422-3212 Alglucerase injection :: Ceredase :: Replacement therapy in patients with Type II and III Gaucher's disease. :: 21-07-1995 :: Genzyme Corporation :: One Kendall Square :: Cambridge MA 02139-1562 alicaforsen :: Treatment of pouchitis. :: 24-06-2008 :: Atlantic Healthcare Limited :: Maple House :: Halsted, Essex CO9 4BB :: UNITED KINGDOMAlitretinoin :: Panretin :: Treatment of acute promyelocytic leukemia :: 10-04-1992 :: Ligand Pharmaceuticals, Inc. :: 10275 Science Center Dr. :: San Diego CA 92121-1117 allantoin :: Alwextin :: Treatment of skin blistering and erosions associated with inherited epidermolysis bullosa :: 21-11-2002 :: Alwyn Company, Inc. :: 2301 Highway 60 East :: Lake Crystal MN 56055Allogeneic human aortic endothelial cells cultured in a porcine gelatin matrix :: Vascugel (r) :: Prevention of arteriovenous fistula or arteriovenous graft failure in patients with end satge renal disease receiving hemodialysis or preparing for hemodialysis :: 03-04-2009 :: Pervasis Therapeutics, Inc. :: One Kendall Square :: First Floor :: Cambridge MA 02139 Allogeneic human retinal pigment epithelial cells on gelatin microcarriers :: Spheramine :: Treatment of Hoehn and Yahr stage 3 and 4 Parkinson's disease. :: 18-07-1997 :: Bayer Healthcare Pharmaceuticals, Inc. :: Post Office Box 1000 :: 50 Division Street, Suite 503 :: Montville NJ 07045-1000allogeneic mesenchymal precursor cells derived from ex vivo healthy donors harvested from iliac crest. :: Treatment of insufficient hematopoietic stem cell production in patients with hematologic malignancies who have failed treatment with conventional chemotherapy. :: 12-09-2008 :: Angioblast Systems, Inc. :: 275 Madison Avenue :: New York NY 10016Allogeneic peripheral blood mononuclear cells sensitized against patient alloantigens by mixed lymphocyte culture :: CYTOIMPLANT :: Treatment of pancreatic cancer :: 13-06-1997 :: Applied Immunotherapeutics, LLC :: 14132 E. Firestone Boulevard :: Santa Fe Springs CA 90670Allogeneic retinal epithelial cells transfected with plasmid vector expressing ciliary neurotrophic growth factor :: Treatment of retinitis pigmentosa :: 01-09-2004 :: Neurotech USA, Inc. :: 6 Blackstone Valley Place :: Lincoln RI 02865Allogeneic T-cells cultured with anti-CD3 and IL-2; transduced with retroviral vector (SFCMM-3), expressing herpes simplex 1 virus-thymidine kinase (HSV-TK) and truncated low affinity nerve growth factor receptor; selected with anti-low affinity nerve gro :: "Immunotherapy for acceleration of T-cell reconstitution in patients undergoing allogeneic hematopoietic stem cell transplantation" :: 28-01-2005 :: MolMed S.p.A. :: Via Olgettina 58 :: Milan 20132 :: ITALYAllopurinol riboside :: Treatment of cutaneous and visceral leishmaniasis. :: 04-12-1985 :: Burroughs Wellcome Company :: 3030 Cornwallis Road :: P.O. Box 12700 :: Research Triangle Park NC 27709 Allopurinol riboside :: Treatment of Chagas' disease. :: 04-12-1985 :: Burroughs Wellcome Company :: 3030 Cornwallis Road :: P.O. Box 12700 :: Research Triangle Park NC 27709 Allopurinol sodium :: Ex-vivo preservation of cadaveric kidneys for transplantation :: 09-11-1987 :: Burroughs Wellcome Company :: 3030 Cornwallis Road :: Research Triangle Pk NC 27709Alpha-1-acid glycoprotein :: Treatment of cocaine overdose :: 05-03-2004 :: Bio Products Laboratory :: Dagger Lane, Elstree, Hertfordshire :: WD6 3BX :: UNITED KINGDOMAlpha-1-acid glycoprotein :: Treatment of tricyclic antidepressant poisoning :: 17-03-2004 :: Bio Products Laboratory :: Dagger Lane :: Elstree, Hertfordshire :: UNITED KINGDOMAlpha-1-antitrypsin (recombinant DNA Origin) :: As supplementation therapy for alpha-1-antitrypsin deficiency in the ZZ phenotype population. :: 01-01-1984 :: Chiron Corporation :: 4560 Horton Street :: Emeryville CA 94608-2916 Alpha1-antitrypsin(human) :: Treatment of bronchiectasis :: 03-04-2008 :: Kamada, Ltd. :: 7 Sapir Street :: Ness Ziona :: ISRAELAlpha1-Proteinase Inhibitor (Human) :: Inhalation therapy for the the treatment of congential deficiency of alpha1-proteinase inhibitor. :: 22-12-2004 :: Kamada Ltd. :: Kiryat Weizmann :: ISRAELAlpha1-Proteinase Inhibitor (Human) :: ARC-API :: Treatment of cystic fibrosis :: 01-09-2004 :: Kamada Ltd. :: Kiryat Weizmann :: ISRAELalpha1-proteinase inhibitor (human) :: Treatment of cystic fibrosis :: 20-02-2009 :: CSL Behring LLC :: 1020 First Avenue :: King of Prussia PA 19406Alpha1-proteinase inhibitor (human) :: For slowing the progression of emphysema in alpha1-antitrypsin deficient patients. :: 24-11-1999 :: CSL Behring L.L.C. :: 1020 First Ave. :: PO Box 61501 :: King of Prussia PA 19406-0901Alpha-galactosidase A :: Fabrase :: Treatment of Fabry's disease. :: 20-07-1990 :: Desnick, Robert J. M.D. :: The Mount Sinai School Of Medicine :: Fifth Avenue at 100th Street, Box 1203 :: New York NY 10029 Alpha-galactosidase A :: CC-galactosidase :: Treatment of alpha-galactosidase A deficiency (Fabry's disease). :: 17-06-1991 :: David Calhoun, Ph.D. :: Department of Chemistry :: Convent Avenue & 138th Street :: New York NY 10031 Alpha-galactosidase A :: Replagal :: Long-term enzyme replacement therapy for the treatment of Fabry disease. :: 22-06-1998 :: Shire Human Genetic Therapies, Inc. :: 700 Main Street :: Cambridge MA 02139Alpha-melanocyte stimulating hormone :: Prevention and treatment of intrinsic acute renal failure due to ischemia. :: 19-08-1997 :: National Institute of Diabetes, and Digestive and Kidney Diseases :: National Institutes of Health, 31 Center Drive MSC :: Building 31, Room 9N-222 :: Bethesda MD 20892-2560Alpha-tocopherol quinone :: Treatment of inherited mitochondrial respiratory chain diseases :: 28-03-2006 :: Penwest Pharmaceuticals Company :: 39 Old Ridgebury Road :: Suite 11 :: Danbury CT 06810 Alprostadil :: Treatment of severe peripheral arterial occlusive disease (critical limb ischemia) in patients where other procedures, grafts or angioplasty, are not indicated. :: 20-10-1993 :: Schwarz Pharma, Inc. :: P.O. Box 2038 :: Milwaukee WI 53201alteplase :: Activase :: Treatment of intraventricular hemmorage associated with intracerebral hemmorrhage :: 27-01-2003 :: Daniel F. Hanley, MD :: Johns Hopkins University :: 600 N. Wolfe St., Jefferson 1-109 :: Baltimore MD 21287 Alvocidib :: Teatment of B-cell chronic lymphocytic leukemia (B-CLL) or prolymphocytic leukemia arising from CLL. :: 13-04-2007 :: Sanofi-Aventis US, Inc. :: 55 Corporate Drive :: Bridgewater NJ 08807ALX-0081 nanobody, directed towards the human A1 domain of von Willebrand factor :: Treatment of thrombotic thrombocytopenic purpura :: 14-04-2009 :: Ablynx NV :: Technologiepark 4 :: B-9052 :: Zwijnaarde :: BELGIUMAMG 531 :: Treatment of thrombocytopenia associated with myelodysplasia syndrome :: 31-10-2007 :: Amgen Inc. :: One Amgen Center Drive :: Thousand Oaks CA 91320-1799 Amifostine :: Ethyol :: Treatment of myelodysplastic syndromes. :: 04-10-1999 :: Medimmune Oncology, Inc. :: One MedImmune Way :: Gaithersburg MD 20878Amifostine :: Ethyol :: For use as a chemoprotective agent for cisplatin in the treatment of metastatic melanoma. :: 30-05-1990 :: Medimmune LLC :: One MedImmune Way :: Gaithersburg MD 20878Amifostine :: Ethyol :: For use as a chemoprotective agent for cyclophosphamide in the treatment of advanced ovarian carcinoma. :: 30-05-1990 :: Medimmune, LLC :: One MedImmune Way :: Gaithersburg MD 20878Amifostine :: Ethyol :: For the reduction of the incidence and severity of toxicities associated with cisplatin administration. :: 24-11-1998 :: Medimmune LLC :: One MedImmune Way :: Gaithersburg MD 20878Amikacin :: SLIT Amikacin :: Treatment of bronchopulmonary Pseudomonas aeruginosa infections in cystic fibrosis patients :: 09-03-2006 :: Transave, Inc. :: 11 Deer Park Drive :: Monmouth Junction NJ 08852-1923 Amiloride HCl solution for inhalation :: Treatment of cystic fibrosis. :: 18-07-1990 :: Glaxo Wellcome Research and Development :: 5 Moore Drive :: PO Box 13398 :: Research Triangle Park NC 27709 Aminocaproic acid :: Caprogel :: For the topical treatment of traumatic hyphema of the eye. :: 06-01-1995 :: Eastern Virginia Medical School :: Department of Ophthalomology :: 880 Kempsville Road, Suite 2500 :: Norfolk VA 23502-3990Aminolevulinic acid hydrochloride :: Levulan :: Treatment of esophageal dysplasia :: 20-03-2007 :: DUSA Pharmaceuticals, Inc. :: 25 Upton Drive :: Wilmington MA 01887Aminosalicylate sodium :: Treatment of Crohn's disease. :: 06-04-1993 :: Syncom Pharmaceuticals, Inc. :: 66 Hanover Road :: Florham Park NJ 07932Aminosidine :: Paromomycin :: Treatment of visceral leishmaniasis :: 29-03-2005 :: The Institute for One World Health :: 580 California Street :: San Francisco CA 94104Aminosidine :: Paromomycin :: Treatment of visceral leishmaniasis (kala-azar). :: 09-09-1994 :: Kanyok, Thomas P. Pharm.D. :: University of Illinois at Chicago College of Pharm :: 833 South Wood Street (m/c886) Rm. 176 :: Chicago IL 60612 Aminosidine :: Gabbromicina :: Treatment of tuberculosis. :: 14-05-1993 :: Kanyok, Thomas P. Pharm.D. :: University Of Illinois At Chicago College of Pharm :: 833 South Wood Street (m/c886) Rm. 176 :: Chicago IL 60612 Aminosidine :: Gabbromicina :: Treatment of Mycobacterium avium complex. :: 15-11-1993 :: Kanyok, Thomas P. Pharm.D. :: University of Illinois at Chicago College of Pharm :: 833 South Wood Street (m/c886) Rm. 176 :: Chicago IL 60612 Amiodarone :: Amio-Aqueous :: Treatment of incessant ventricular tachycardia. :: 17-08-1993 :: Academic Pharmaceuticals, Inc. :: 21 N. Skokie Valley Highway :: Suite G3 :: Lake Bluff IL 60044 ammonium tetrathiomolybdate :: Treatment of idiopathic pulmonary fibrosis :: 05-05-2008 :: Pipex Pharmaceuticals, Inc. :: 3930 Varsity Drive :: Ann Arbor MI 48108Ammonium tetrathiomolybdate :: Coprexa :: Treatment of Wilson's disease. :: 31-01-1994 :: Pipex Pharmaceuticals, Inc. :: 3930 Varsity Drive :: Ann Arbor MI 48108Amonafide L-malate :: Xanafide :: Treatment of acute myeloid leukemia :: 20-12-2006 :: Xanthus Pharmaceuticals, Inc. :: 300 Technology Square :: Cambridge MA 02139Amphotericin B inhalation powder :: Prevention of pulmonary fungal infections in patients at risk for aspergillosis due to immunosuppressive therapy including those receiving organ or stem cell transplants, or teated with chemotherapy or radiation for hematologic malignancies :: 15-12-2005 :: Novartis Pharmaceuticals Corporation :: 150 Industrial Road :: San Carlos CA 94070Amphotericin B lipid complex :: Abelcet :: Treatment of invasive protothecosis. :: 21-08-1996 :: The Liposome Company, Inc. :: One Research Way :: Princeton NJ 08540Amphotericin B lipid complex :: Abelcet :: Treatment of invasive sporotrichosis. :: 23-09-1996 :: The Liposome Company, Inc. :: One Research Way :: Princeton NJ 08540Amphotericin B lipid complex :: Abelcet :: Treatment of invasive coccidioidomycosis. :: 06-05-1996 :: The Liposome Company, Inc. :: One Research Way :: Princeton NJ 08540Amphotericin B lipid complex :: Abelcet :: Treatment of invasive zygomycosis. :: 06-05-1996 :: The Liposome Company, Inc. :: One Research Way :: Princeton NJ 08540Amphotericin B lipid complex :: Abelcet :: Treatment of invasive candidiasis. :: 27-06-1996 :: The Liposome Company, Inc. :: One Research Way :: Princeton NJ 08540amrubicin :: Treatment of small cell lung cancer :: 10-03-2008 :: Celgene Corporation :: 9900 W. 109th Street :: Suite 300 :: Overland Park KS 66210 Amsacrine :: Amsidyl :: Treatment of acute adult leukemia. :: 07-12-1984 :: Warner-Lambert Company :: Parke-Davis Pharmaceutical Research Division :: 2800 Plymouth Road :: Ann Arbor MI 48106 Amyl nitrite, sodium nitrite, sodium thiosulfate :: Cyanide Antidote Kit :: Treatment of cyanide poisoning :: 18-12-2006 :: Akorn, Inc. :: 2500 Millbrook Drive :: Buffalo Grove IL 60089Anagrelide :: Agrylin :: Treatment of thrombocytosis in chronic myelogenous leukemia. :: 14-07-1986 :: Roberts Pharmaceutical Corp. :: Meridian Center II :: 4 Industrial Way West :: Eatontown NJ 07724-2274Anagrelide :: Agrylin :: Treatment of polycythemia vera. :: 11-06-1985 :: Roberts Pharmaceutical Corp. :: Meridian Center II :: 4 Industrial Way West :: Eatontown NJ 07724-2274Ananain, comosain :: Vianain :: For the enzymatic debridement of severe burns. :: 21-01-1992 :: Genzyme Corporation :: One Kendall Square :: Cambridge MA 02139Anaritide acetate :: Auriculin :: Treatment of patients with acute renal failure. :: 27-08-1992 :: Scios, Inc. :: 2450 Bayshore Parkway :: Mountain View CA 94043Anaritide acetate :: Auriculin :: Improvement of early renal allograft function following renal transplantation. :: 10-04-1992 :: Scios, Inc. :: 2450 Bayshore Parkway :: Mountain View CA 94043Anatibant :: Treatment of patients having experienced a severe traumatic brain injury (Glasgow Coma Scale 3 to 8) in order to decrease early mortality and improve long-term functional and neurological outcome :: 15-04-2005 :: Xytis, Inc. :: 400 South El Camino Real :: Suite 1200 :: San Mateo CA 94402-1703Ancrod :: Viprinex :: "To establish and maintain anticoagulation in heparin-intolerant patients undergoing cardiopulmonary bypass." :: 20-10-1989 :: Knoll Pharmaceutical Company :: 3000 Continental Dr., North :: Mt. Olive NJ 07828Angiotensin 1-7 :: MARstem :: Treatment of myelodysplastic syndrome :: 03-08-2001 :: Maret Pharmaceutical Corporation :: 4041 MacArthur Boulevard, Suite 375 :: Newport Beach CA 92660Angiotensin 1-7 :: Treatment of neutropenia associated with autologous bone marrow transplantation. :: 16-02-2000 :: Maret Pharmaceuticals :: 4041 MacArthur Blvd. :: Suite 375 :: Newport Beach CA 92660 anthrax immune globulin (human) :: Treatment of toxemia associated with inhalational anthrax. :: 29-07-2008 :: Cangene Corporation :: 155 Innovation Drive :: R3T 5Y3 :: CANADAanti human Nogo-A human monoclonal antibody :: Treatment of acute spinal cord injury :: 20-10-2008 :: Novartis Pharmaceuticals Corporation :: One Health Plaza :: East Hanover NJ 07936Anti pan T lymphocyte monoclonal antibody :: Anti-t Lymphocyte Immunotoxin Xmmly-h65-rta :: For ex-vivo treatment to eliminate mature T cells from potential bone marrow grafts. :: 29-01-1986 :: Xoma Corporation :: 2910 Seventh Street :: Berkeley CA 94710Anti pan T lymphocyte monoclonal antibody :: Anti-t Lymphocyte Immunotoxin Xmmly-h65-rta :: For in-vivo treatment of bone marrow recipients to prevent graft rejection and graft versus host disease. :: 29-01-1986 :: Xoma Corporation :: 2910 Seventh Street :: Berkeley CA 94710antiangiogenic components extracted from marine cartilage :: Neovastat (AE-941) :: Treatment of renal cell carcinoma :: 16-10-2002 :: AEterna Zentaris, Inc. :: Dr. Claude Hariton :: Chief Medical Officer, VP, Cli :: Quebec G1P 4P5, Canada :: CANADAanti-CD23 IgG1, kappa monoclonal antibody :: Treatment of chronic lymphocytic leukemia :: 12-02-2003 :: Biogen IDEC, Inc. :: 5200 Research Place :: San Diego CA 92122 anti-CD30 Fc engineered humanized monoclonal antibody :: Treatment of Hodgkin lymphoma :: 02-12-2008 :: Xencor, Inc. :: 111 W. Lemon Avenue :: Monrovia CA 91016Anti-CD40 mAb :: Treatment of chronic lymphocytic leukemia :: 06-10-2005 :: Seattle Genetics, Inc. :: 21823 30th Drive Southeast :: Bothell WA 98021Anti-CD45 monoclonal antibodies :: Prevention of acute graft rejection of human organ transplants. :: 10-09-1990 :: Baxter Healthcare Corporation :: 1620 Waukegan Road :: Mcgaw Park IL 60085Anti-CEA Sheep-human chimeric monoclonal antibody labeled w/iodine-131 (KAb201) :: Treatment of pancreatic cancer :: 21-05-2003 :: Xenova Biomedix Limited CELTIC PHARMA :: 957 Buckingham Avenue :: Berkshire SL1 4NL :: UNITED KINGDOMAnti-cytomegalovirus monoclonal antibodies :: Prevention of human cytomegalovirus infection in bone marrow and organ transplant patients. :: 02-05-1990 :: Biomedical Research Institute :: 345 North Smith Avenue :: St. Paul MN 55102Anti-cytomegalovirus monoclonal antibodies :: Treatment of human cytomegalovirus infection in bone marrow and organ transplant patients. :: 02-05-1990 :: Biomedical Research Institute :: 345 North Smith Avenue :: St. Paul MN 55102Anti-cytomegalovirus monoclonal antibodies :: Prevention of human cytomegalovirus infection in patients diagnosed with AIDS. :: 03-05-1990 :: Biomedical Research Institute :: 345 North Smith Avenue :: St. Paul MN 55102Anti-cytomegalovirus monoclonal antibodies :: Treatment of human cytomegalovirus infection in patients diagnosed with AIDS. :: 03-05-1990 :: Biomedical Research Institute :: 345 North Smith Avenue :: St. Paul MN 55102Anti-cytotoxic T lymphocyte antigen 4 monoclonal antibody :: Treatment of stage IIb to stage IV metastatic melanoma :: 18-09-2006 :: Pfizer Global Research & Development :: 50 Pequot Avenue :: New London CT 06320Antiepilepsirine :: Treatment of drug resistant generalized tonic-clonic epilepsy in children and adults. :: 23-03-1989 :: Children's Hospital :: 700 Children's Drive :: Columbus OH 43205Antihemophilic factor (recombinant) formulated with sucrose reconstituted with liposome diluent :: Kogenate(r) FS :: Treatment of hemophilia A :: 29-04-2009 :: Bayer HealthCare LLC :: 555 Whiteplains Road :: Tarrytown NY 10591-5124 anti-interferon-gamma Fab from goats :: For the treatment of immunologic corneal allograft rejection :: 18-11-2003 :: Advanced Biotherapy, Inc. :: 6355 Topanga Canyon Blvd. :: Suite 510 :: Woodland Hills CA 91367 Antimelanoma Antibody XMMME-001-DTPA 111 Indium :: Antimelanoma Antibody XMMME-001-DTPA 111 Indium :: Diagnostic use in imaging systemic and nodal melanoma metastasis. :: 14-11-1984 :: Xoma Corporation :: 2910 Seventh Street :: Berkeley CA 94710Antimelanoma Antibody XMMME-001-RTA :: Antimelanoma Antibody XMMME-001-RTA :: Treatment of stage III melanoma not amenable to surgical resection. :: 14-11-1984 :: Xoma Corporation :: 2910 Seventh Street :: Berkeley CA 94710antineoplaston A10, antineoplaston AS2-1 :: Treatment of gliomas :: 30-10-2008 :: Burzynski Research Institute, Inc. :: 9432 Old Katy Road :: Houston TX 77055Antipyrine Test :: For use as an index of hepatic drug-metabolizing capacity. :: 21-02-1985 :: Upsher-Smith Laboratories, Inc :: 4905 23rd Avenue North :: Minneapolis MN 55447Antisense 20-mer oligonucleotide complementary to R2 component of ribonucleotide reductase mRNA :: Treatment of acute myeloid leukemia :: 15-04-2005 :: Lorus Therapeutics, Inc. :: 2 Meridan Road :: M9W 4Z7 :: CANADAantisense 20-mer phosphorothioate oligonucleotide [complementary to the coding region of R2 component of the human ribonucleotide reductase mRNA] :: GTI-2040 :: Treatment for renal cell carcinoma :: 12-03-2003 :: Lorus Therapeutics, Inc :: 2 Meridan Road :: M9W427 :: CANADAAntisense inhibitor of apoB-100 :: Treatment of homozygous familial hypercholesterolemia :: 23-05-2006 :: Genzyme Corporation :: Drug & Biomaterial R&D :: 153 Second Avenue :: Waltham MA 02451 Antisense oligonucleotide directed against connexin43 :: Nexagon :: Treatment of persistent corneal epithelial defects :: 27-04-2009 :: CoDa Therapeutics, Inc. :: 10505 Sorrento Valley Road :: San Diego CA 92121Anti-T cell receptor murine monoclonal antibody :: Prophylaxis of acute rejection of solid organ transplantation :: 03-04-2009 :: Tolera Therapeutics, Inc. :: 4717 Campus Drive #800 :: Kalamazoo MI 49008Anti-tap-72 immunotoxin :: Xomazyme-791 :: Treatment of metastatic colorectal adenocarcinoma. :: 06-03-1987 :: Xoma Corporation :: 2910 Seventh Street :: Berkeley CA 94710Anti-tenascin 81C6 monoclonal antibody labeled w/ I 131 :: Neuradiab :: Treatment of primary malignant brain tumors :: 04-10-2005 :: Bradmer Pharmaceuticals, Inc. :: 9900 Corporate Campus Drive :: Suite 3000 :: Louisville KY 40223 Antithrombin III (human) concentrate IV :: Kybernin P :: For prophylaxis and treatment of thromboembolic episodes in patients with genetic AT-III deficiency. :: 02-07-1985 :: CSL Behring :: 1020 First Ave. :: PO Box 61501 :: King of Prussia PA 19406-0901Antithrombin III human :: Antithrombin III human :: Preventing or arresting episodes of thrombosis in patients with congenital AT-III deficiency and/or to prevent the occurrence of thrombosis in patients with AT-III deficiency who have undergone trauma or who are about to undergo surgery or parturition. :: 02-01-1986 :: American National Red Cross :: 9312 Old Georgetown Road :: Bethesda MD 20814Anti-thymocyte Globulin (Rabbitt) :: Thymoglobulin :: Treatment of myelodysplastic syndrome (MDS) :: 06-09-2000 :: Genzyme Corporation :: 500 Kendall Street :: Cambridge MA 02142Anti-thymocyte serum :: Nashville Rabbit Anti-thymocyte Serum :: Treatment of allograft rejection, including solid organ (kidney, liver, heart, lung, and pancreas) and bone marrow transplantation. :: 02-06-1993 :: Applied Medical Research :: 1600 Hayes Street :: Nashville TN 37203anti-T-lymphocyte immune globulin, rabbit :: Prophylaxis of acute allograft rejection in adult recipients in solid organ transplantation. :: 12-09-2008 :: Fresenius Biotech North America :: 920 Winter Street :: Waltham MA 02451Antivenin crotaline (pit-viper) equine immune F(ab)2) :: Antivipmyn :: Treatment of envenomation by Crotaline snakes :: 29-01-2004 :: Rare Disease Therapeutics, Inc. :: 2550 Meridian Blvd :: Franklin TN 37067Antivenom (crotalidae) purified (avian) :: Treatment of envenomation by poisonous snakes belonging to the Crotalidae family. :: 12-02-1991 :: Ophidian Pharmaceuticals, Inc. :: 5445 East Cheryl Parkway :: Madison WI 53711Anti-von Willebrand Aptamer :: Treatment of thrombotic thrombocytopenic purpura :: 09-04-2008 :: Archemix Corporation :: 300 Third Street :: Cambridge MA 02142AP1903 :: Treatment of acute graft-versus-host disease in patients undergoing bone marrow transplantation. :: 24-11-1999 :: Ariad Pharmaceuticals, Inc. :: 26 Landsdowne St. :: Cambridge MA 02139-4234 APL 400-020 V-Beta DNA vaccine :: Treatment of cutaneous T cell lymphoma. :: 08-03-1995 :: Wyeth-Lederle Vaccines and Pediatrics :: 211 Bailey Rd. :: West Henrietta NY 14586-9728 Apomorphine :: For use as rescue treatment for early morning motor dysfunction in late-stage Parkinson's disease. :: 20-10-1997 :: Scherer DDS :: Frankland Road :: Swindon SN5 8RU :: Wiltshire :: UNITED KINGDOMApomorphine :: Treatment of the on-off fluctuations associated with late-stage Parkinson's disease. :: 17-07-1995 :: Pentech Pharmaceuticals, Inc. :: 1110 Lake Cook Rd. :: Suite 257 :: Buffalo Grove IL 60089 Apomorphine hydrochloride :: For the treatment of patients in a vegetative state or minimally conscious state for up to 12 months following a severe traumatic brain injury (traumatic or spontaneous) :: 23-05-2006 :: NeuroHealing Pharmaceuticals, Inc. :: 50 Undine Road :: Newton MA 02135AQ-13 (4-aminoquinoline analog) :: Treatment of malaria :: 12-09-2008 :: Immtech Pharmaceuticals, Inc. :: 150 Fairway Drive :: Vernon Hills IL 60061Arcitumomab :: 99m Tc-labeled CEA-Scan :: Diagnosis and localization of primary, residual, recurrent and metastatic medullary thyroid carcinoma. :: 10-05-1996 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Arenegyr :: Treatment of malignant plueral mesothelioma :: 22-08-2008 :: MolMed S.p.A. :: Via Olgettina 58 :: Milan :: ITALYArginine butyrate :: Treatment of sickle cell disease and beta thalassemia. :: 25-05-1994 :: Vertex Pharmaceuticals Inc. :: 130 Waverly Street :: Cambridge MA 02139-4242 Arginine butyrate :: Treatment of beta-hemoglobinopathies and beta-thalassemia. :: 07-04-1992 :: Perrine, Susan P., M.D. :: Boston University :: Cancer Research Center :: Boston MA 02118 arimoclomol :: Treatment of amyotrophic lateral sclerosis :: 29-03-2005 :: CytRx Corporation :: 3030 Bunker Hill Street :: Suite 105 :: San Diego CA 92109 Aripiprazole :: Abilify :: Treatment of Tourette's syndrome :: 25-01-2006 :: Floyd R. Sallee, M.D., Ph.D. :: University of Cincinnati School of Medicine/ :: P. O. Box 670669 231 Albert Sabin Way :: Cincinnati OH 45267-0559arsenic :: Trisenox :: Treatment of acute myelocytic leukemia subtypes M0, M1, M2, M4, M5, M6 and M7 :: 02-11-2001 :: Cephalon, Inc. :: 41 Moores Road :: Frazer PA 19355Arsenic trioxide :: Trisenox :: Treatment of malignant glioma :: 04-03-2005 :: Cephalon Inc :: 41 Moores Road :: P. O. Box 4011 :: Frazer PA 19355 arsenic trioxide :: Trisenox :: Treatment of chronic myeloid leukemia :: 18-10-2001 :: Cephalon, Inc. :: 41 Moores Road :: Frazer PA 19355Arsenic trioxide :: Trisenox :: Treatment of multiple myeloma. :: 28-04-2000 :: Cephalon, Inc. :: 41 Moores Road :: Frazer PA 19355arsenic trioxide :: Trisenox :: Treatment of liver cancer :: 13-06-2003 :: Cephalon, Inc. :: 41 Moores Road :: Frazer PA 19355Arsenic trioxide :: Trisenox :: Treatment of chronic lymphocytic leukemia :: 13-05-2003 :: Cephalon, Inc. :: 41 Moores Road :: Frazer PA 19355arsenic trioxide :: Trisenox :: Treatment of myelodysplastic syndrome. :: 17-07-2000 :: Cephalon, Inc. :: 41 Moores Road :: P.O. Box 4011 :: Frazer PA 19355 artemether/lumefantrine :: Coartem :: For the treatment of infections due to Plasmodium falciparum or mixed infections including P. falciparum. :: 31-08-2007 :: Novartis Pharmaceuticals :: Bldg 405/4051 :: One Health Plaza :: East Hanover NJ 07936-1080Artesunate :: Treatment of malaria. :: 19-07-1999 :: World Health Organization :: Special Programme for Research and Training in Tro :: Via Appia , Geneva 27 :: SWITZERLANDArtesunate :: Immediate treatment of malaria :: 28-03-2006 :: US Army Medical Materiel Development Activity :: Office of the Surgeon General :: 622 Neiman Street :: Ft. Detrick MD 21702-9240arylsulfatase A (rhARSA) :: Treatment of metachromatic leukodystrophy. :: 27-02-2008 :: Shire Human Genetic Therapies, Inc. :: 700 Main Street :: Cambridge MA 02139As-101 :: Treatment of acquired immunodeficiency syndrome. :: 09-11-1987 :: NPDC-AS101, Inc. :: 783 Jersey Avenue :: New Brunswick NJ 08901Ascorbic acid :: Ascor L 500 :: Treatment of scurvy :: 31-08-2007 :: McGuff Pharmaceuticals Inc. :: 2921 W. McArthur Blvd. :: Santa Ana CA 92704-6929 Atomoxetine hydrochloride :: STRATTERA :: Treatment of Tourette's Syndrome :: 26-08-2003 :: Eli Lilly & Company :: Lilly Corporate Center :: Indianapolis IN 46285Atovaquone :: Mepron :: Primary prophylaxis of HIV-infected persons at high risk for developing Toxoplasma gondii encephalitis. :: 16-03-1993 :: GlaxoSmithKline, Inc. :: 5 Moore Drive :: PO Box 13398 :: Research Triangle Park NC 27709 Atovaquone :: Mepron :: Treatment and suppression of Toxoplasma gondii encephalitis. :: 16-03-1993 :: GlaxoSmithKline, Inc. :: 5 Moore Drive :: PO Box 13398 :: Research Triangle Park NC 27709-3398Attenuated autologous cancer cells and granulocyte macrophage colony stimulating factor in combination with activated autologous blood derived T-cells :: Treatment of primary central nervous system malignancies :: 27-04-2007 :: TVAX Biomedical, LLC :: 8060 Reeder Street :: Lenexa KS 66214-1554 autologous antigen presenting cells pulsed with autologous tumor Ig idiotype :: Mylovenge :: Treatment of multiple myeloma :: 18-04-2002 :: Dendreon Corporation :: 3005 First Avenue :: Seattle WA 98121Autologous cultured endothelial cells on a donor human corneal disk :: Treatment of Fuch's dystrophy, pseudophakic bullous keratopathy, and bullous keratopathy :: 01-06-2007 :: Cellular Bioengineering, Inc. :: 1946 Young Street :: Honolulu HI 96826Autologous dendritic cells pulsed with autologous antigens from primay malignant brain tumor cells :: DCVax-Brain :: Treatment of primary brain malignant cancer :: 29-11-2002 :: Northwest Biotherapeutics, Inc. :: 22322 20th Avenue SE :: Suite 150 :: Bothell WA 98021 Autologous DNP-conjugated tumor vaccine :: M-Vax :: For adjuvant therapy in melanoma patients with surgically resectable lymph node metastasis (Stage III and limited Stage IV disease). :: 23-02-1999 :: Avax Technologies, Inc. :: 9200 Indian Creek Parkway :: Building 9, Suite 200 :: Overland Park KS 66210 Autologous incubated macrophage :: Therapy to improve the motor and sensory neurological outcome in acute cases of spinal cord injury :: 03-09-2004 :: Proneuron Biotechnologies, Inc. :: 2029 Century Park East :: Sixth Floor :: Los Angeles CA 90067 autologous lymphocytes depleted ex vivo of immunoreactive T cells using 4,5 :: Theralux photodynamic therapy :: Treatment of chronic graft versus host disease :: 03-04-2008 :: Kiadis Pharma Canada, Inc. :: 2525 Marie Curie :: Montreal (Quebec) H4S 2E1 :: CANADAautologous olfactory neural progenitors :: RhinoCytes :: Treatment of amyotrophic lateral sclerosis :: 31-12-2008 :: RhinoCyte, Inc. :: 201 E. Jefferson Street :: Louisville KY 40202-1246 Autologous olfactory neural progenitors :: RhinoCytes :: Treatment of spinal cord injury patients with ASIA Impairment grades A, B, or C :: 01-02-2008 :: RhinoCyte, Inc. :: 201 E. Jefferson Street :: Louisville KY 40202-1246 Autologous or allogeneic limbal epithelial stem cells expanded ex vivo on human amniotic membrane :: Treatment of ocular surface diseases that are characterized by total limbal stem cell deficiency :: 14-07-2005 :: TissueTech, Inc. :: 7000 SW 97th Avenue :: Miami FL 33173autologous tumor-derived gp96 heat shock protein-peptide complex :: Oncophage :: Treatment of renal cell carcinoma :: 10-05-2002 :: Antigenics, Inc. :: 3 Forbes Rd. :: Lexington MA 02421autologous tumor-derived gp96 heat shock protein-peptide complex :: Oncophage :: Treatment of metastatic melanoma :: 11-07-2002 :: Antigenics, Inc. :: 3 Forbes Rd. :: l MA 02421Autolymphocyte therapy :: Treatment of renal cell carcinoma. :: 12-07-1994 :: Cytogen Corporation :: 600 College Road East :: CN 5308 :: Princeton NJ 08540-5308aviptadil :: Treatment of pulmonary arterial hypertension :: 22-02-2005 :: Biogen Idec MA, Inc. :: 14 Cambridge Center :: Cambridge MA 02142axitinib :: Treatment of pancreatic cancer :: 31-05-2007 :: Pfizer, Inc. :: 10646 Science Center Drive :: San Diego CA 92121Azathioprine :: Imuran :: Treatment of oral manifestations of graft-versus-host disease. :: 14-09-1999 :: Oral Solutions, Inc. :: 787 Seventh Ave., 48th Floor :: New York NY 10019aztreonam :: Inhalation therapy for control of gram-negative bacteria in the respiratory tract of patients with cystic fibrosis :: 12-03-2002 :: Gilead Sciences (formerly Corus Pharma) :: 2025 First Ave. :: Suite 800 :: Seattle WA 98121 Bacillus Calmette-Guerin vaccine :: Treatment of stage IIb through IV metastatic melanoma :: 09-08-2006 :: OncoVac Corporation :: P. O. Box 970 :: Pacific Palisades CA 90272Bacitracin :: Altracin :: Treatment of antibiotic-associated pseudomembranous enterocolitis caused by toxins A and B elaborated by Clostridium difficile. :: 13-03-1984 :: A. L. Laboratories, Inc. :: One Executive Drive :: P.O. Box 1399 :: Fort Lee NJ 07024 Baclofen :: Treatment of intractable spasticity due to multiple sclerosis or spinal cord injury. :: 16-12-1991 :: Infusaid, Inc. :: 1400 Providence Highway :: Norwood MA 02062Baclofen :: Lioresal Intrathecal :: Treatment of spasticity associated with cerebral palsy. :: 26-09-1994 :: Medtronic, Inc. :: 800 53rd Avenue N.E. :: P.O. 1250 :: Minneapolis MN 55440-9087baclofen :: Treatment of dystonia :: 02-12-2003 :: Medtronic Neurological :: 710 Medtronic Parkway NE :: Minneapolis MN 55432-5604 Bardoxolone :: Treatment of pancreatic cancer :: 06-08-2008 :: Reata Pharmaceuticals, Inc. :: 2801 Gateway Drive :: Irving TX 75063beclomethasone :: Treatment of pediatriac patients with ulcerative colitis :: 04-03-2009 :: Eurand Pharmaceuticals, Inc. :: 790 Township Line Road :: Yardley PA 19067beclomethasone 17,21-dipropionate :: Bec :: Prevention of gastrointestinal graft-versus-host disease :: 28-08-2001 :: DOR BioPharma, Inc. :: 29 Emmons Drive :: Suite C-10 :: Princeton NJ 08540 beclomethasone 17,21-diproprionate :: Treatment of pediatric patients with Crohn disease. :: 18-12-2007 :: DOR BioPharma, Inc. :: 29 Emmons Drive :: Suite C-10 :: Princeton NJ 08540 Beclomethasone dipropionate :: For oral administration in the treatment of intestinal graft-versus-host disease. :: 27-03-1998 :: DOR BioPharma, Inc. :: 29 Emmons Drive :: Suite C-10 :: Princeton NJ 08540 belatacept :: Prophylaxis of organ rejection in renal allograft recipients :: 20-02-2008 :: Bristol-Myers Squibb Company :: P. O. Box 4000 :: Princeton NJ 08543-4000 Benzophenone-3, octylmethoxycinnamate, avobenzone, titanium dioxide, zinc oxide :: Total Block VL SPF 75 :: For the prevention of visible light induced skin photosensitivity as a result of porfimer sodium photodynamic therapy :: 13-08-2001 :: Fallien Cosmeceuticals Ltd. :: 677 W. Dekalb Pike :: King of Prussia PA 19406Benzydamine hydrochloride :: Tantum :: Prophylactic treatment of oral mucositis resulting from radiation therapy for head and neck cancer. :: 18-05-1998 :: Angelini Pharmaceuticals, Inc. :: 70 Grand Avenue :: River Edge NJ 07661Benzylpenicillin, benzylpenicilloic, benzylpenilloic acid :: Pre-Pen/MDM :: Assessing the risk of administrating penicillin when it is the preferred drug of choice in adult patients who have previously received penicillin and have a history of clinical sensitivity. :: 29-09-1987 :: AllerQuest LLC :: 836 Farmington Avenue :: Suite 207 :: West Hanford CT 06119-1551Beractant :: Survanta Intratracheal Suspension :: Treatment of full-term newborn infants with respiratory failure caused by meconium aspiration syndrome, persistent pulmonary hypertension of the newborn, or pneumonia and sepsis. :: 20-12-1993 :: Ross Laboratories :: 625 Cleveland Avenue :: Columbus OH 43215Beraprost :: Treatment of pulmonary arterial hypertension associated with any New York Heart Association classification (Class I, II, III, or IV). :: 29-04-1999 :: LungRx, Inc. :: 1104 Spring Street :: Silver Spring MD 20910Beta alethine :: Betathine :: Treatment of metastatic melanoma. :: 24-03-1997 :: Dovetail Technologies, Inc. :: Bldg. 337, Paint Branch Drive :: College Park MD 20742Beta alethine :: Betathine :: Treatment of multiple myeloma. :: 24-03-1997 :: Dovetail Technologies, Inc. :: Bldg. 337, Paint Branch Drive :: College Park MD 20742Betahistine dihydrochloride :: Treatment of obesity associated with Prader Willi syndrome :: 08-11-2007 :: Floyd R. Sallee, M.D., Ph.D. :: University of Cincinnati School of Medicine :: ML 0559 :: Cincinnati OH 45267-0559Bethanidine sulfate :: Prevention of recurrence of primary ventricular fibrillation. :: 24-11-1989 :: Medco Research, Inc. :: 8455 Beverly Blvd. :: Suite 308 :: Los Angeles CA 90048 Bethanidine sulfate :: Treatment of primary ventricular fibrillation. :: 20-09-1988 :: Medco Research, Inc. :: 8455 Beverly Blvd. :: Suite 308 :: Los Angeles CA 90048 Betulinic acid :: Topical treatment of metastatic melanoma :: 09-08-2007 :: Advanced Life Sciences, Inc. (ALS) :: 1440 Davey Road :: Woodridge IL 60517Bevacizamub :: Avastin :: Treatment of malignant glioma :: 26-05-2006 :: Genentech, Inc. :: 1 DNA Way :: South San Francisco CA 94080-4990 Bevacizumab :: Avastin :: Therapeutic treatment of patients with ovarian cancer :: 09-02-2006 :: Genentech, Inc. :: 1 DNA Way :: South San Francisco CA 94080-4990 Bevacizumab :: Avastin :: Treatment of pancreatic cancer :: 20-10-2004 :: Genentech, Inc. :: 1 DNA Way, MS #242 :: South San Francisco CA 94080-4990 Bevacizumab :: Avastin :: Treatment of renal cell carcinoma :: 06-11-2003 :: Genentech, Inc. :: 1 DNA Way :: South San Francisco CA 94080-4990 bifidobacterium infantis 35624 :: Treatment of pediatric ulcerative colitis :: 24-03-2008 :: Alimentary Health Limited :: Cork Airport Business Park, Building 2800 :: Cork :: IRELANDbifidobacterium longum infantis 35624 :: Treatment of pediatric Crohn's disease :: 16-01-2003 :: Alimentary Health Limited :: Guardwell, Kinsale :: County Cork :: IRELANDBindarit :: Treatment of lupus nephritis. :: 03-02-1998 :: Angelini Pharmaceuticals, Inc. :: 70 Grand Avenue :: Suite 109 :: River Edge NJ 07661 Bioartificial liver system utilizing xenogenic hepatocytes in a hollow fiber bioreactor cartridge (BAL) :: Treatment of patients with acute liver failure presenting with encephalopathy deteriorating beyond Parson's grade 2 :: 11-02-2002 :: Excorp Medical, Inc. :: Suite 235 :: 7200 Hudson Blvd. :: Oakdale MN 55128 Bio-engineered oral mucosal tissue :: "For use as a graft for restoring a cornea-like epithelial phenotype to substitute for the normal corneal epithelium that is lost in patients due to total limbal stem cell deficiency" :: 27-04-2006 :: TissueTech, Inc. :: 7000 SW 97th Avenue :: Miami FL 33173Bis(4-fluorophenyl)phenylacetamide :: Treatment of sickle cell disease. :: 02-03-2000 :: ICAgen Inc. :: Ion Channel Advances :: PO Box 14487 :: Durham NC 27709 Bispecific molecule with two linked murine single-chain Fv regions against CD3 & CD19 :: Treatment of prolymphocytic leukemia :: 16-05-2008 :: MedImmune, LLC :: One MedImmune Way :: Gaithersburg MD 20878Bispecific molecule with two linked murine single-chain Fv regions against CD3 & CD19 :: Treatment for hairy cell leukemia. :: 16-05-2008 :: MedImmune, LLC :: One MedImmune Way :: Gaithersburg MD 20878Bispecific molecule with two linked murine single-chain Fv regions against CD3 & CD19 :: Treatment of chronic lymphocytic leukemia :: 16-05-2008 :: MedImmune, LLC :: One MedImmune Way :: Gaithersburg MD 20878Bispecific molecule with two linked murine single-chain Fv regions against CD3 & CD19 :: Treatment of acute lymphocytic leukemia :: 16-05-2008 :: MedImmune, LLC :: One MedImmune Way :: Gaithersburg MD 20878Bispecific molecule with two linked murine single-chain Fv regions directed against CD3 & CD19 :: Treatment of indolent B-cell lymphoma, excluding CLL and NHL with CNS involvement :: 06-02-2006 :: MedImmune, LLC :: One MedImmune Way :: Gaithersburg MD 20878bivalirudin :: Angiomax :: For use as an anticoagulant in patients with or at risk of heparin-induced thrombocytopenia/heparin-induced thrombocytopenia thrombosis syndrome :: 02-11-2005 :: The Medicines Company :: 8 Sylvan Way :: Parsippany NJ 07054Bleomycin :: Blenoxane :: Treatment of pancreatic cancer. :: 09-02-1999 :: Genetronics, Inc. :: 11199 Sorrento Valley Rd. :: San Diego CA 92121-1334 BMY-45622 :: Treatment of ovarian cancer. :: 15-10-1990 :: Bristol-Myers Squibb :: 5 Research Parkway :: Wallingford CT 06492bosentan :: Tracleer :: Treatment of idiopathic pulmonary fibrosis :: 30-09-2008 :: Actelion Pharmaceuticals Ltd :: Gewerbestrasse 16 :: CH-4123 :: SWITZERLANDbosutinib :: Treatment of chronic myelogenous leukemia. :: Wyeth Pharmaceuticals, Inc. :: 87 Cambridge Park Drive :: Cambridge MA 02140Botulinum toxin type A :: Dysport :: Treatment of dynamic muscle contractures in pediatric cerebral palsy patients. :: 20-10-1999 :: Ipsen Limited :: 1 Bath Rd., Maidenhead :: Berkshire SL6 4UH :: UNITED KINGDOMBotulinum toxin type A :: Dysport :: Treatment of spasmodic torticollis (cervical dystonia). :: 12-08-1998 :: Ipsen Biopharm Limited :: 1 Bath Road :: Maidenhead :: Berkshire, SL6 4UH :: UNITED KINGDOMBotulinum toxin type A :: Dysport :: Treatment of essential blepharospasm. :: 23-03-1989 :: Porton International, Inc. :: 1155 15th Street, N.W., #315 :: Washington DC 20005Botulinum toxin type A :: Botox :: Treatment of dynamic muscle contracture in pediatric cerebral palsy patients. :: 06-12-1991 :: Allergan, Inc. :: 2525 Dupont Drive :: P.O. Box 19534 :: Irvine CA 92623-9534Botulinum toxin type A :: Treatment of synkinetic closure of the eyelid associated with VII cranial nerve aberrant regeneration. :: 15-09-1992 :: Botulinum Toxin Research Associates, Inc. :: 1261 Furnace Brook Parkway :: Quincy MA 02169Botulinum toxin type F :: Treatment of spasmodic torticollis (cervical dystonia). :: 24-10-1991 :: Ipsen Limited :: 27 Maple Street :: Milford MA 01757-3650 Botulinum toxin type F :: Treatment of essential blepharospasm. :: 05-12-1991 :: Ipsen Limited (name changed from Porton International Inc) :: 27 Maple Street :: Milford MA 01757-3650 Bovine colostrum :: Treatment of AIDS-related diarrhea. :: 19-11-1990 :: Hastings, Donald DVM :: 1030 North Parkview Drive :: Bismarck ND 58501Bovine immunoglobulin concentrate, Cryptosporidium parvum :: Sporidin-G :: Treatment and symptomatic relief of Cryptosporidium parvum infection of the gastrointestinal tract in immunocompromised patients. :: 01-03-1994 :: GalaGen, Inc. :: 4001 Lexington Avenue North :: Arden Hills MN 55126Bovine whey protein concentrate :: Immuno-C :: Treatment of cryptosporidiosis caused by the presence of Cryptosporidium parvum in the gastrointestinal tract of patients who are immunodeficient/immunocompromised or immunocompetent. :: 30-09-1993 :: Biomune Systems, Inc. :: 540 Arapeen Drive, Suite 202 :: Salt Lake City UT 84108Branched chain amino acids :: Treatment of amyotrophic lateral sclerosis. :: 23-12-1988 :: Mount Sinai Medical Center :: One Gustave L. Levy Place :: New York NY 10029Brimonidine :: Alphagan :: Treatment of anterior ischemic optic neuropathy. :: 07-02-2000 :: Allergan, Inc. :: 2525 Dupont Dr. :: P.O. Box 19534 :: Irvine CA 92623-9534Brivaracetam :: Treatment of symtomatic myoclonus :: 05-10-2005 :: UCB Pharma, Inc. :: 1950 Lake Park Drive :: Smyra GA 30080Brivudin :: Adjunct treatment of pancreatic cancer :: 15-11-2007 :: SciClone Pharmaceuticals, Inc. :: 901 Mariner's Island Blvd. :: San Mateo CA 94404Bromhexine :: Bisolvon :: Treatment of mild to moderate keratoconjunctivitis sicca in patients with Sjogren's syndrome. :: 15-05-1989 :: Boehringer Ingelheim Pharmaceuticals, Inc. :: 900 Ridgebury Road, Box 368 :: Ridgefield CT 06877-0368 Broxuridine :: Broxine/Neomark :: Radiation sensitizer in the treatment of primary brain tumors. :: 18-09-1995 :: NeoPharm, Inc. :: 225 East Deerpath, Suite 250 :: Lake Forest IL 60045bryostatin-1 :: For use in combination with paclitaxel in the treatment of esophageal cancer :: 03-12-2001 :: GPC Biotech, Inc. :: 610 Lincoln Street :: Waltham MA 02451Buffered Ursodeoxycholic Acid :: Ursocarb :: Treatment of pruritus in patients with Alagille Syndrome :: 03-09-2004 :: Digestive Care, Inc. :: 1120 Win Drive :: Bethlehem PA 18017bupivacaine :: Transdur :: Relief of persistent pain asociated with postherpetic neuralgia :: 18-06-2008 :: Alpha Pharmaceuticals, LLC :: One New England Avenue :: Piscataway NJ 08854Busulfan :: Spartaject :: For use as preparative therapy for malignancies treated with bone marrow transplantation. :: 21-04-1994 :: Sparta Pharmaceuticals, Inc. :: 111 Rock Road :: Horsham PA 19044-2310 Busulfan :: Spartajet-Busulfan :: Intrathecal therapy for neoplastic meningitis :: 05-03-2001 :: SuperGen, Inc. :: 4140 Dublin Boulevard :: Dublin CA 94568busulfan :: Partaject :: Preparative therapy for pediatric patients undergoing bone marrow transplantation :: 25-11-2002 :: SuperGen, Inc. :: 4140 Dublin Blvd :: Suite 200 :: Dublin CA 94568 Busulfan :: Spartaject :: Treatment of primary brain malignancies. :: 07-07-1997 :: SuperGen, Inc. :: Two Annabel Lane, Suite 220 :: San Ramon CA 94583Buthionine sulfoxamine :: For use in children as a modulator of chemotherapy for the treatment of pediatric patients with neuroblastoma :: 05-10-2005 :: USC-CHLA Institute for Pediatric Clinical Research :: Childrens Hospital of Los Angeles MS 55 :: Los Angeles CA 90027Buthionine sulfoxamine :: Use as a modulator of chemotherapy for the treatment of pediatric patients with primary malignant brain tumors :: 05-10-2005 :: USC-CHLA Institute for Pediatric Clinical Research :: Childrens Hospital of Los Angeles :: 4650 Sunset Blvd, MS 55 :: Los Angeles CA 90027 Butyrylcholinesterase :: Treatment of post-surgical apnea. :: 30-09-1992 :: Shire Laboratories Inc. :: 1550 East Gude Drive :: Rockville MD 20850Butyrylcholinesterase :: For the reduction and clearance of toxic blood levels of cocaine encountered during a drug overdose. :: 25-03-1992 :: Shire Laboratories Inc. :: 1550 East Gude Drive :: Rockville MD 20850BW 12C :: Treatment of sickle cell disease. :: 23-10-1987 :: Burroughs Wellcome Company :: 3030 Cornwallis Road :: P.O. Box 12700 :: Research Triangle Pk NC 27709 C1 esterase inhibitor (human) :: Treatment and prevention of angioedema caused by C1-esterase inhibitor deficiency. :: 21-08-1996 :: Alpha Therapeutic Corporation :: 5555 Valley Boulevard :: Los Angeles CA 90032C1-esterase-inhibitor, human, pasteurized :: Berinert P :: Prevention and/or treatment of acute attacks of hereditary angioedema. :: 16-10-1992 :: CSL Behring L.L.C. :: 1020 First Ave. :: PO Box 61501 :: King of Prussia PA 19406-0901C1-inhibitor :: C1-inhibitor (human) vapor heated, Immuno :: Prevention of acute attacks of angioedema, including short-term prophylaxis for patients requiring dental or other surgical procedures. :: 30-08-1990 :: Baxter Healthcare Corp. :: One Baxter Way :: Westlake Village CA 91362C1-inhibitor :: C1-inhibitor (human) vapor heated, Immuno :: Treatment of acute attacks of angioedema. :: 30-08-1990 :: Baxter Healthcare Corp. :: Hyland Division (Baxter Hyland) :: 550 North Brand Blvd. :: Glendale CA 91203 cAC10-vcMMAE (4) :: Treatment of Hodgkin's lymphoma. :: 30-01-2007 :: Seattle Genetics, Inc. :: 21823 30th Drive Southeast :: Bothell WA 98021Calcitonin salmon nasal spray :: Miacalcin Nasal Spray :: Treatment of symptomatic Paget's disease (osteitis deformans). :: 29-10-1990 :: Sandoz Pharmaceuticals Corp. :: 59 Route 10 :: East Hanover NJ 07936Calcium acetate :: Treatment of hyperphosphatemia in end stage renal disease. :: 27-06-1989 :: Pharmedic Company :: 28101 Ballard Road, Suite F :: Lake Forest IL 60045Calcium carbonate :: R & D calcium carbonate/600 :: Treatment of hyperphosphatemia in patients with end stage renal disease. :: 06-06-1990 :: R & D Laboratories, Inc. :: 4204 Glencoe Avenue :: Marina Del Rey CA 90292Calcium gluconate :: Calgonate :: For use as a wash for hydrofluoric acid spills on human skin. :: 20-11-1997 :: Calgonate Corp. :: 3310 South Ocean Blvd :: Unit 132 :: Highland Beach FL 33487 Calcium gluconate gel :: H-F Gel :: For use in the emergency topical treatment of hydrogen fluoride (hydrofluoric acid) burns. :: 21-05-1991 :: Calgonate Corporation :: 3310 South Ocean Blvd :: Unit 132 :: Highland Beach FL 33487 Calcium gluconate gel 2.5% :: Emergency topical treatment of hydrogen fluoride (hydrofluoric acid) burns. :: 10-09-1990 :: Paddock Laboratories, Inc. :: 3940 Quebec Avenue North :: Minneapolis MN 55427Calfactant :: Infasurf :: Acute respiratory distress syndrome (ARDS) :: 05-09-2000 :: Pneuma Pharmaceuticals, Inc. :: 1576 Sweet Home Road :: Suite 114 :: Amherst NY 14228 canakinumab :: Treatment of systemic onset juvenile idiopathic arthritis :: 30-09-2008 :: Novartis Pharmaceuticals Corporation :: One Health Plaza :: East Hanover NJ 07936-1080 Capsaicin :: Treatment of postherpetic neuralgia. :: 03-08-2005 :: TheraQuest Biosciences, LLC :: 146 Medinah Drive :: Blue Bell PA 19422-3212 Capsaicin :: Treatment of intermetatarsal neuroma (Morton's Neuroma) that does not respond to conservative treatment and requires either neurectomy or neurolysis :: 29-09-2006 :: Anesiva, Inc. :: 650 Gateway Blvd :: South San Francisco CA 94080capsaicin :: Treatment of erythromelalgia :: 23-10-2002 :: NeurogesX, Inc. :: 981F Industrial Road :: San Carlos CA 94070Capsaicin :: Treatment of painful HIV-associated neuropathy :: 02-05-2003 :: NeurogesX, Inc. :: San Carlos Business Park :: 981F Industrial Road :: San Carols CA 94070-4117Carbamylglutamic acid :: Treatment of N-acetylglutamate synthetase deficiency. :: 20-01-1998 :: Orphan Europe :: Immeuble "Le Guillaumet" :: Cedex 70 :: FRANCEcarbon monoxide :: Covox :: For use in the reduction of the incidence and severity of delayed graft function in patients undergoing solid organ transplanation. :: 24-06-2008 :: INO Therapeutics :: 6 Route 173 :: Clinton NJ 08809Carbovir :: Treatment of persons with AIDS and in patients with symptomatic HIV infection and a CD4 count less than 200/mm3. :: 13-12-1989 :: Glaxo Wellcome Inc. :: 5 Moore Drive :: Research Triangle Park NC 27709cardiotrophin-1 :: To protect the liver from ischemia-reperfusion injury inherent to the procedure of transplantation. :: 24-06-2008 :: Digna Biotech, S.L. :: Avenids Carlos III de Noble :: Pamplona (Navarra) :: SPAINcarfilzomib :: Treatment of multiple myeloma :: 18-01-2008 :: Proteolix, Inc. :: 333 Allerton Avenue :: South San Francisco CA 94080Carmustine :: Treatment of intracranial malignancies. :: 03-07-2000 :: Direct Therapeutics, Inc. :: 460 Seaport Court :: Suite 220 :: Redwood CA 94063 Cascara sagrada fluid extract :: Treatment of oral drug overdosage to speed lower bowel evacuation. :: 21-03-1989 :: Intramed Corporation :: 102 Tremont Way :: Augusta GA 30907Catumaxomab :: Removab :: Treatment of ovarian cancer :: 09-06-2006 :: Fresenius Biotech North America, Inc. :: 99 Hayden Avenue :: Lexington MA 02420-9192 CD4 human truncated 369 AA polypeptide :: Soluble T4 :: Treatment of acquired immunodeficiency syndrome. :: 21-11-1989 :: SmithKline Beecham :: Route 23 & Woodmont Ave., P.O. Box 1510 :: King Of Prussia PA 19406CD5-T lymphocyte immunotoxin :: Xomazyme-H65 :: Treatment of graft versus host disease and/or rejection in patients who have received bone marrow transplants. :: 27-08-1987 :: Xoma Corporation :: 2910 Seventh Street :: Berkeley CA 94710CDP571 :: Treatment of Crohn's disease. :: 11-12-1997 :: Celltech Chiroscience Limited :: 216 Bath Road :: Slough SL1 4EN :: UNITED KINGDOMCDX-110 :: Treatment of EGFRvIII-expressing glioblastoma multiforme :: 19-11-2007 :: Pfizer Global Research & Development :: MS 6025-B4179 :: 50 Pequot Avenue :: New London CT 06320 Ceftriaxone sodium :: Rocephin :: Treatment of amyotrophic lateral sclerosis :: 28-03-2006 :: Mass General Hospital :: Merit E. Cudkowicz, MD, MSc :: Building 149 13th Street, Room 2274 :: Charlestown MA 02129 Cells produced using the AastromReplicelle System and SC-I Therapy Kit :: For use in patients receiving high dose chemotherapy who are unable to generate an acceptable dose of peripheral blood stem cells and who have a sufficient bone marrow aspirate without morphological evidence of tumor :: 10-07-2002 :: Aastrom Biosciences Incorporated :: P.O. Box 376 :: Ann Arbor MI 48106cenersen :: Aezea :: Treatment of stage IIB through IV melanoma :: 18-06-2008 :: Eleos, Inc. :: 3033 Campus Drive :: Plymouth MN 55441cenersen :: Treatment of acute myeloid leukemia :: 08-05-2006 :: Eleos, Inc. :: 7824 Jackson Street :: Omaha NE 68114cenersen :: Aezea :: Treatment of chronic lymphocytic leukemia :: 27-02-2008 :: Eleos, Inc. :: One Valmont Plaza – Corporate Headquarters :: Omaha NE 68154Centruroides immune F(ab)2 :: Alacramyn :: Treatment of scorpion envenomations requiring medical attention. :: 12-06-2000 :: Istituto Bioclon S.A. de C.V. :: Calzada de Tlalpan No. 4687 :: Tlalpan :: MEXICOcethromycin :: Prophylactic treatment of patients exposed to inhalation anthrax. :: 28-02-2007 :: Advanced LIfe Sciences, Inc. :: 1440 Davey Road :: Woodridge IL 60517Cetiedil citrate injection :: Treatment of sickle cell disease crisis. :: 22-12-1988 :: Baker Cummins Pharmaceuticals, Inc. cetuximab :: Erbitux :: Treatment of pancreatic cancer :: 15-06-2007 :: ImClone Systems Incorporated :: 33 ImClone Drive :: Branchburg NJ 08876Chenodeoxycholic acid :: Chenofalk :: Treatment of cerebrotendinous xanthomatosis :: 29-01-2004 :: Dr. Falk Pharma GmbH :: Leinenweberstrasse 5 :: 9041 Freiburg, GERMANY :: GERMANYchenodeoxycholic acid :: Treatment of cerebrotendinous xanthomatosis :: 12-02-2007 :: Sigma-Tau Pharmaceuticals, Inc. :: 9841 Washingtonian Blvd :: Suite 500 :: Gaithersburg MD 20878 Chimeric (human-murine) G250 IgG monoclonal antibody :: Treatment of renal cell carcinoma. :: 24-07-2000 :: Wilex Biotechnology GmbH :: Grillparzerstrasse 10B :: 81675 Munich :: GERMANYchimeric (murine-human) IgG1 mAb against IL-6 :: Treatment of multiple myeloma :: 11-10-2005 :: Centocor, Inc. :: 200 Great Valley Parkway :: Malvern PA 19355-1307 Chimeric (murine-human) IgG1k monoclonal antibody against interleukin-6 :: Treatment of Castleman's disease :: 26-05-2006 :: Centocor, Inc. :: 200 Great Valley Parkway :: Malvern PA 19355-1307 Chimeric monoclonal antibodies :: For treatment of shiga-toxin producing bacterial infection. :: 04-10-2005 :: Thallion Pharmaceuticals, Inc. :: 7150 Alexander-Fleming :: Montreal, Quebec, H4S 2C8 :: CANADAChimeric monoclonal antibody to mesothelin :: Treatment of pancreatic cancer :: 31-10-2006 :: Morphotek, Inc. :: 210 Welsh Pool Road :: Exton PA 19341Chimeric M-T412 (human-murine) IgG monoclonal anti-CD4 :: Treatment of multiple sclerosis. :: 05-06-1991 :: Centocor, Inc. :: 244 Great Valley Parkway :: Malvern PA 19355chimeric murine/human IgG1 monoclonal antibody to human interleukin-3 receptor alpha chain :: Treatment of acute myeloid leukemia :: 03-04-2009 :: CSl Limited :: 45 Poplar Road :: AUSTRALIAChimeric, humanized monoclonal antibody to staphylococcus :: Prophylaxis of Staphylococcus epidermidis sepsis in low birth weight (1500 grams or less) infants. :: 03-08-2000 :: Biosynexus, Inc. :: 9298 Gaither Road :: Rockville MD 20877Chlorhexidine gluconate mouthrinse :: Peridex :: For use in the amelioration of oral mucositis associated with cytoreductive therapy used in conditioning patients for bone marrow transplantation therapy. :: 18-08-1986 :: Procter & Gamble Company :: Sharon Wood Technical Center :: 11370 Reed Hartman Highway :: Cincinnati OH 45241 chlorotoxin :: Treatment of stage IIb, IIc, III & IV melanoma :: 02-12-2008 :: TransMolecular, Inc. :: 840 Memorial Drive :: Cambridge MA 02139Chlorotoxin :: Treatment of malignant glioma :: 18-12-2007 :: TransMolecular, Inc. :: 840 Memorial Drive :: Cambridge MA 02139cholest-4-en-3-one, oxime :: Treatment of spinal muscular atrophy. :: 17-02-2009 :: Trophos SA :: Parc scientifique de Luminy :: 13288 Marseille cedex :: FRANCEcholic acid (3 alpha, 7 alpha, 12 alpha trihydroxy 5-beta cholanolic acid) :: Falkochol :: Treatment of inborn errors of cholesterol and bile acid synthesis and metabolism :: 18-07-2003 :: Cincinnati Children's Hospital Medical Center :: 3333 Burnet Ave. :: MLC 5006 :: Cincinnati OH 45229-3039Choline chloride :: IntraChol :: Prevention and/or treatment of choline deficiency in patients on long-term parenteral nutrition :: 20-07-2006 :: Alan L. Buchman, M.D., M.S.P.H. :: Feinberg School of Medicine, Dept. of Gastroentero :: 676 N. St. Clair St., Suite 1400 :: Chicago IL 60611 Choline chloride :: Intrachol :: Treatment of choline deficiency, specifically the choline deficiency, hepatic steatosis, and cholestasis, associated with long-term parenteral nutrition. :: 10-02-1994 :: Bioniche Pharma USA LLC :: 272 E. Deerpath Road :: Suite 304 :: Lake Forest IL 60045 Chondrocyte-alginate gel suspension :: For use in correcting vesicoureteral reflux in the pediatric population. :: 01-12-1997 :: Curis, Inc. :: 61 Moulton Street :: Cambridge MA 02138Chondroitinase :: Treatment of patients undergoing vitrectomy. :: 09-02-1995 :: Bausch & Lomb Pharmaceuticals, Inc. :: 8500 Hidden River Pkwy. :: Tampa FL 33637cicletanine hydrochloride :: Treatment for pulmonary arterial hypertension. :: 24-06-2008 :: Gilead Sciences, Inc. :: 77575 W. 103rd Avenue :: Suite 102 :: Westminster CO 80021 cilengitide :: Treatment of malignant glioma :: 27-05-2005 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370Ciliary neurotrophic factor :: Treatment of amyotrophic lateral sclerosis. :: 30-01-1992 :: Regeneron Pharmaceuticals Inc :: 777 Old Saw Mill River Road :: Tarrytown NY 10591Ciliary neurotrophic factor, recombinant human :: Treatment of motor neuron disease (including amyotrophic lateral sclerosis, progressive muscular atrophy, progressive bulbar palsy, and primary lateral sclerosis). :: 08-05-1992 :: Syntex-Synergen Neuroscience :: 3200 Walnut Street :: Boulder CO 80301Ciliary neurotrophic factor, recombinant human :: Treatment of spinal muscular atrophies. :: 02-04-1992 :: Syntex-Synergen Neuroscience :: 3200 Walnut Street :: Boulder CO 80301Cisplatin in liposomal formulation :: SLIT Cisplatin for inhalation :: Treatment of osteogenic sarcoma metastatic to the lung :: 20-03-2007 :: Transave, Inc. :: 11 Deer Park Drive :: Monmouth Junction NJ 08852-1923 Cisplatin/epinephrine :: IntraDose :: Treatment of metastatic malignant melanoma. :: 07-09-2000 :: Matrix Pharmaceutical, Inc. :: 34700 Campus Drive :: Fremont CA 94555-3612 Cisplatin/epinephrine :: IntraDose :: Treatment of squamous cell carcinoma of the head and neck. :: 03-04-2000 :: Matrix Pharmaceutical, Inc. :: 34700 Campus Drive :: Fremont CA 94555-3612 Civamide :: Zucapsaicin :: Treatment of postherpetic neuralgia of the trigeminal nerve :: 09-12-2002 :: Winston Laboratories, Inc. :: 100 Fairway Drive, Suite 134 :: Vernon Hills IL 60061Cladribine :: Leustatin :: Treatment of acute myeloid leukemia. :: 20-07-1990 :: Ortho Biotech Oncology Research & Development :: Johnson & Johnson Pharmaceutical Research & Dev., :: 920 US Highway 202 :: Raritan NJ 08869 Cladribine :: Leustatin Injection :: Treatment of chronic lymphocytic leukemia. :: 31-12-1990 :: Ortho Biotech Oncology Research & Development :: Unit of J & J Pharmaceutical Research & Developmen :: P. O. Box 300 :: Raritan NJ 08869 Cladribine :: Mylinax :: Treatment of the chronic progressive form of multiple sclerosis. :: 19-04-1994 :: Johnson & Johnson Pharmaceutical R & D, LLC :: 920 Route 202 :: PO Box 300 :: Raritan NJ 08869-0602Cladribine :: Leustatin Injection :: Treatment of non-Hodgkin's lymphoma. :: 19-04-1993 :: Ortho Biotech Oncology Research & Development :: Unit of J & J Pharmaceutical Research & Dev., LLC :: 920 Route 202 South, P.O. Box 300 :: Raritan NJ 08869-0602Clazosentan :: Erajet :: Treatment of cerebral vasospasm following subarachnoid hemorrhage :: 16-02-2006 :: Actelion Pharmaceuticals Ltd. :: Gewerbestrasse 16 :: SWITZERLANDClindamycin :: Cleocin :: Prevention of Pneumocystis carinii pneumonia in AIDS patients. :: 28-10-1988 :: Pfizer Inc. :: 235 East 42nd Street :: 150-3-46 :: New York NY 10017 Clindamycin :: Cleocin :: Treatment of Pneumocystis carinii pneumonia associated with AIDS patients. :: 28-10-1988 :: Pharmacia & Upjohn :: 7000 Portage Road :: Unit 0633-298-113 :: Kalamazoo MI 49001-0199Clindamycin hydrochloride :: Treatment of sarcoidosis :: 09-08-2006 :: Autoimmunity Research Foundation :: 3423 Hill Canyon Avenue :: Thousand Oaks CA 91360clobazam :: Treatment of Lennox-Gastaut Syndrome. :: 18-12-2007 :: Lundbeck, Inc. :: Four Parkway North :: Deerfield IL 60015clofarabine :: Clofarex :: Treatment of acute myelogenous leukemia :: 14-03-2002 :: Genzyme Corp (Ilex Products, Inc.) :: 4545 Horizon Hill Blvd. :: San Antonio TX 78229-2263 Clonazepam :: Klonopin :: Treatment of hyperekplexia (startle disease). :: 04-08-1994 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110Clonazepam Intranasal Spray :: Treatment of recurrent acute repetitive seizures :: 19-12-2007 :: Jazz Pharmaceuticals, Inc. :: 3180 Porter Drive :: Palo Alto CA 94304Clostridial collagenase :: Treatment of advanced (involutional or residual stage) Dupuytren's disease. :: 23-05-1996 :: Auxilium Pharmaceuticals, Inc. :: 40 Valley Stream Parkway :: Malvern PA 19335Clotrimazole :: Topical treatment of children and adults with pouchitis :: 14-06-2005 :: Effective Pharmaceuticals, Inc. :: 150 Broadway :: Suite 1800 :: New York NY 10038 Clotrimazole :: Treatment of Huntington's disease :: 13-03-2006 :: EnVivo Pharmaceuticals, Inc. :: 480 Arsenal Street :: Watertown MA 02472Clotrimazole :: Treatment of sickle cell disease. :: 24-04-1995 :: Brugnara, Carlo M.D. :: The Children's Hospital :: 300 Longwood Avenue, Bader 760 :: Boston MA 02115 c-myb antisense oligodeoxynucleotide :: Treatment of chronic myelogenous leukemia :: 22-02-2005 :: Genta, Inc. :: Two Connell Drive :: Berkeley Heights NJ 07922Coagulation factor VIIa (recombinant) :: NovoSeven :: Prevention of bleeding episodes in Glanzmann's thrombasthenia :: 18-06-2004 :: Novo Nordisk, Inc. :: 100 College Road West :: Princeton NJ 08540Coagulation factor VIIa (Recombinant) :: NovoSeven :: Treatment of bleeding episodes in Glanzmann's thrombasthenia :: 18-06-2004 :: Novo Nordisk, Inc. :: 100 College Road West :: Princeton NJ 08540Coagulation Factor VIIa (Recombinant) :: NovoSeven :: Treatment of bleeding in patients experiencing intracranial hemorrhage. :: 03-10-2006 :: Novo Nordisk, Inc. :: 100 College Road West :: Princeton NJ 08540cobiprostone :: Treatment of cystic fibrosis :: 14-11-2002 :: Sucampo Pharma Americas, Inc. :: 4520 East-West Highway :: Third Floor :: Bethesda MD 20814 coccidioidin SD Skin Test Antigen :: For the diagnosis of Coccidioidomycosis. :: 19-12-2007 :: Allermed Labortories, Inc. :: 7203 Convoy Court :: San Diego CA 92111Coenzyme Q10 :: Treatment of Huntington's disease :: 05-03-2001 :: Integrative Therapeutics, Inc. :: 825 Challenger Drive :: Green Bay WI 54311Colchicine :: Treatment of familial Mediterranean fever :: 25-09-2007 :: AR Scientific, Inc. :: 1100 Orthodox Street :: Philadelphia PA 19124Colchicine :: Treatment of Behcet's Syndrome :: 25-09-2007 :: AR Scientific, Inc. :: 1100 Orthodox Street :: Philadelphia PA 19124Colchicine :: For arresting the progression of neurologic disability caused by chronic progressive multiple sclerosis. :: 09-12-1985 :: Pharmacontrol Corporation :: 661 Palisade Ave., P.O. Box 931 :: Englewood Cliffs NJ 07632Collagenase (lyophilized) for injection :: Plaquase :: Treatment of Peyronie's disease. :: 12-03-1996 :: Auxilium Pharmaceuticals, Inc. :: 40 Valley Stream Parkway :: Malvern PA 19355Combretastatin A4 phosphate :: Treatment of ovarian cancer :: 08-05-2006 :: OXiGENE, Inc. :: 230 Third Avenue :: Waltham MA 02451Combretastatin A4 Phosphate :: Treatment of anaplastic thyroid cancer, medullary thyroid cancer, and stage IV papillary or follicular thyroid cancer :: 23-07-2003 :: OXiGENE, Inc :: 321 Arsenal Street :: Watertown MA 02472conjugate of human transferrin and a mutant diphtheria toxin (CRM 107) :: TransMID :: Treatment of malignant tumors of the central nervous system :: 03-12-2001 :: Xenova Biomedix Limited :: 957 Budkingham Avenue :: Slough :: UNITED KINGDOMconjugated bile acids :: COBARTin :: Treatment of steatorrhea in patients with short bowel syndrome :: 18-07-2003 :: Jarrow Formulas, Inc. :: 1824 S. Robertson Blvd. :: Los Angeles CA 90035-4317 Contulakin-G :: Intrathecal treatment of neuropathic pain associated with spinal cord injury :: 07-07-2005 :: Cognetix, Inc. :: 421 Wakara Way :: Salt Lake City UT 84108Cordycepin :: Treatment of TdT-positive acute lymphocytic leukemia :: 05-07-2007 :: OncoVista, Inc. :: 14785 Omicron Drive :: San Antonio TX 78245Corticotropin-releasing factor, human :: Xerecept :: Treatment of peritumoral brain edema. :: 06-04-1998 :: Neurobiological Technologies, Inc. :: 1387 Marina Way South :: Richmond CA 94804Coumarin :: Onkolox :: Treatment of renal cell carcinoma. :: 22-12-1994 :: Drossapharm LTD :: 4002 Basel :: SWITZERLANDCoxsackievirus A21 :: Cavatak :: Treatment of stage II (T4), stage III, and stage IV melanoma :: 15-12-2005 :: Viralytics Limited :: P. O. Box 1045 :: Pymble Business Centre :: AUSTRALIACreatine :: Creapure :: Treatment of Huntington's disease :: 11-10-2005 :: Avicena Group, Inc. :: 228 Hamilton Avenue :: Palo Alto CA 94301creatine :: Creapure :: Treatment of amyotrophic lateral sclerosis :: 12-02-2002 :: Avicena Group, Inc. :: 580 California St. :: Suite 1600 :: San Francisco CA 94104 Cry5B :: Treatment of soil transmitted helminth infection strongyloidiasis :: 05-09-2008 :: University of California, San Diego :: Aroian Laboratory, Div. of Biological Sciences :: Department 0322 :: LaJolla CA 92093-0322Cryptosporidium hyperimmune bovine colostrum IgG concentrate :: Treatment of diarrhea in AIDS patients caused by infection with Cryptosporidium parvum. :: 30-12-1991 :: ImmuCell Corporation :: 56 Evergreen Drive :: Portland ME 04103cultured, partially T-Cell depleted, allogenic thymic tissue for transplantation :: As a therapy for primary immune deficiency resulting from athymia associated with complete DiGeorge Syndrome :: 15-08-2003 :: Duke University Medical Center :: Division of Pediatric Allergy & Immunology :: Erwin Road :: Durham NC 27710 CY-1503 :: Cylexin :: Treatment of neonates and infants undergoing cardiopulmonary bypass during surgical repair of congenital heart lesions. :: 18-07-1997 :: Cytel Corporation :: 3525 John Hopkins Court :: San Diego CA 92121CY-1503 :: Cylexin :: Treatment of post-ischemic pulmonary reperfusion edema following surgical treatment for chronic thromboembolic pulmonary hypertension. :: 22-12-1993 :: Cytel Corporation :: 3525 John Hopkins Court :: San Diego CA 92121CY-1899 :: Treatment of chronic active hepatitis B infection in HLA-A2 positive patients. :: 16-03-1994 :: Cytel Corporation :: 3525 John Hopkins Court :: San Diego CA 92121Cyclo {{(E,Z)-(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)nona-6,8-dienoyl}-L-2-aminobytyrl-N-methyl-glycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl} :: Treatment and chronic control of non-infectious posterior, intermediate and pan-uveitis :: 20-12-2006 :: Lux Biosciences, Inc. :: Hoarborside Financial Center :: Plaza 10, 14th Floor :: Jersey City NJ 07302 Cyclosporin A :: Mitogard :: Treatment of amyotrophic lateral sclerosis and its variants :: 29-10-2004 :: Maas Biolab,LLC :: Tecnology Ventures Corporation Technopolis :: 1155 University Blvd., SE :: Albuquerque NM 87106 cyclosporine :: Prophylaxis of graft-versus-host disease :: 17-02-2009 :: Sigmoid Pharma Limited :: Dublin City University :: IRELANDcyclosporine :: Treatment of graft-versus-host disease :: 17-02-2009 :: Sigmoid Pharma Limited :: Dublin City University :: IRELANDCyclosporine :: Prophylaxis of organ rejection in patients receiving allogeneic lung transplant :: Kristin Miller, CSO, HFD-590. :: 25-11-2003 :: APT Pharmaceuticals, Inc. :: 700 Airport Blvd. :: Suite 350 :: Burlingame CA 94010 Cyclosporine :: Pluminiq :: Treatment of acute rejection in patients requiring allogenic lung transplants :: 25-11-2003 :: APT Pharmaceuticals, Inc. :: 700 Airport Blvd. :: Suite 350 :: Burlingame CA 94010 Cyclosporine 2% ophthalmic ointment :: Treatment of patients at high risk of graft rejection following penetrating keratoplasty. :: 01-08-1991 :: Allergan, Inc. :: 2525 Dupont Drive :: P.O. Box 19534 :: Irvine CA 92623-9534Cyclosporine 2% ophthalmic ointment :: For use in corneal melting syndromes of known or presumed immunologic etiopathogenesis, including Mooren's ulcer. :: 01-08-1991 :: Allergan, Inc. :: 2525 Dupont Drive :: P.O. Box 19534 :: Irvine CA 92623-9534Cyclosporine A :: Treatment of vernal keratoconjunctivitis :: 04-05-2007 :: NOVAGALI Pharma SA :: Batiment Genavenir IV :: F-91058-Evry cedex :: FRANCEcyclosporine A :: Prevention of corneal graft rejection :: 30-09-2008 :: Novagali Pharma S.A. :: 1 rue Pierre Fontaine :: 91058 Evry cedex :: FRANCEcyclosporine A :: NOVA22007 :: Treatment of herpes simplex virus stromal keratitis :: 09-04-2008 :: Novagali Pharma S.A. :: 1 rue Pierre Fontaine :: 91058 Evry cedex :: FRANCECyclosporine A implant :: For the prevention of acute rejection in cornea transplant patients :: 08-01-2007 :: Lux Biosciences, Inc. :: Harborside Financial Center :: Plaza 10, 14th Floor :: Jersey City NJ 07302 Cyclosporine in combination with omega-3 polyunsaturated fatty acids :: Prevention of solid organ graft rejection. :: 06-12-2000 :: RTP Pharma Corporation :: 200 Westpark Corporate Center :: 4364 South Alston Avenue :: Durham NC 27713-2280Cyclosporine ophthalmic :: Optimmune :: Treatment of severe keratoconjunctivitis sicca associated with Sjogren's syndrome. :: 09-11-1988 :: University Of Georgia :: College Of Veterinary Medicine :: Department of Small Animal Medicine :: Athens GA 30602 Cyproterone acetate :: Androcur :: Treatment of severe hirsutism. :: 26-10-1984 :: Berlex Laboratories, Inc. :: 300 Fairfield Road :: Wayne NJ 07470Cys-His-Ala-Val-Cys :: For use in conjunction with melphalen for the treatment of malignant melanoma, AJCC stages IIB, IIC, III and IV :: 14-02-2008 :: Adherex Technologies, Inc. :: 4620 Creekstone Drive :: Durham NC 27703cysteamine :: Treatment of neuronal ceroid lipofuscinoses (Batten disease) :: 06-08-2008 :: Bennu Pharmaceuticals, Inc. (dual EMEA) :: 9 Commercial Blvd. :: Novato CA 94949cysteamine :: Treatment of Huntington's disease :: 09-05-2008 :: Bennu Pharmaceuticals :: 9 Commerical Blvd :: Novato CA 94949Cysteamine :: Treatment of nephropathic cystinosis. :: 01-05-1986 :: Thoene, Jess G., M.D. :: University of Michigan Medical School :: 300 NIB, 1192 SE :: Ann Arbor MI 48109-0408Cysteamine hydrochloride :: Treatment of corneal cystine crystal accumulation in cystinosis patients. :: 19-08-1997 :: Sigma-Tau Pharmaceuticals, Inc. :: 9841 Washingtonian Blvd :: Suite 500 :: Gaithersburg MD 20878 Cystic fibrosis gene therapy :: Treatment of cystic fibrosis. :: 30-06-1992 :: Genzyme Corporation :: One Mountain Rd. :: P.O. Box 9322 :: Framingham MA 01701-9322Cystic fibrosis Tr gene therapy (recombinant adenovirus) :: AdGVCFTR.10 :: Treatment of cystic fibrosis. :: 09-03-1995 :: GenVec, Inc. :: 12111 Parklawn Drive :: Rockville MD 20852Cystic fibrosis transmembrane conductance regulator :: For cystic fibrosis transmembrane conductance regulator protein replacement therapy in cystic fibrosis patients. :: 14-01-1992 :: Genzyme Corporation :: One Mountain Road :: P.O. Box 9322 :: Framingham MA 01701-9322Cystic fibrosis transmembrane conductance regulator gene :: Treatment of cystic fibrosis. :: 08-01-1993 :: Genetic Therapy, Inc. :: 938 Clopper Road :: Gaithersburg MD 20878cytarabine liposome :: DepoCyt :: Treatment of gliomas :: 30-01-2007 :: Bruce Frankel, MD :: Medical University of South Carolina :: 96 Jonathan Lucas Street, Suite 428 CSB :: Charleston SC 29425 Cytarabine:daunorubicin liposome injection :: Treatment of acute myeloid leukemia :: 22-08-2008 :: Celator Pharmaceuticals, Inc. :: 303 B College Road East :: Princeton NJ 08540Cytomegalovirus DNA Vaccine w/Copolymer/Benzalkonium Chloride :: For use in prevention of clinically significant CMV viremia, CMV disease and associated complications in at-risk hematopoietic cell transplant and solid organ transplant populations :: 23-09-2006 :: Vical Inc. :: 10390 Pacific Center Court :: San Diego CA 92121Cytomegalovirus DNA vaccine with plasmids expressing pp65 and gB genes :: Prevention of clinically significant cytomegalovirus (CMV) viremia, CMV disease and asociated complications in at-risk hematopoietic cell transplant and solid transplant populations :: 03-06-2005 :: Vical Incorporated :: 10390 Pacific Center Court :: San Diego CA 92121Cytomegalovirus immune globulin intravenous (human) :: For use in conjunction with ganciclovir sodium for the treatment of cytomegalovirus pneumonia in bone marrow transplant patients. :: 28-01-1991 :: Bayer Corporation :: Pharmaceutical Division, Biological Products :: 400 Morgan Lane :: New Haven CT 06516 Dantrolene sodium :: Dantrium :: Treatment of the neuroleptic malignant syndrome. :: 14-12-1987 :: Norwich Eaton Pharmaceuticals :: P.O. Box 191 :: Norwich NY 13815Dapsone :: Prophylaxis of toxoplasmosis in severely immunocompromised patients with CD4 counts below 100. :: 07-11-1994 :: Jacobus Pharmaceutical Company, Inc. :: 37 Cleveland Lane :: P.O. Box 5290 :: Princeton NJ 08540 Dapsone USP :: Dapsone :: For the combination treatment of Pneumocystis carinii pneumonia in conjunction with trimethoprim. :: 08-01-1992 :: Jacobus Pharmaceutical Company :: 37 Cleveland Lane :: P.O. Box 5290 :: Princeton NJ 08540 Dapsone USP :: Dapsone :: Prophylaxis for Pneumocystis carinii pneumonia. :: 24-12-1991 :: Jacobus Pharmaceutical Company :: 37 Cleveland Lane :: P.O. Box 5290 :: Princeton NJ 08540 Daunorubicin liposomal :: Treatment of acute myeloid leukemia :: 05-09-2008 :: Diatos USA, LLC :: 15310 Amberly Drive :: Tampa FL 33647DEAE-rebeccamycin :: Treatment of bile duct tumors :: 01-03-2004 :: Helsinn Healthcare SA :: Via Pian Scairolo, 6912 Pazzallo :: Lugano :: SWITZERLANDdebrase :: Debridase :: Debridement of acute, deep dermal burns in hospitalized patients :: 20-08-2003 :: MediWound, Ltd. :: 3, Azrieli Center :: Tel-Aviv 67023 :: ISRAELDecitabine :: Dacogen :: Treatment of acute myeloid leukemia :: 04-08-2006 :: Eisai Medical Research, Inc. :: 6611 Tributary Street :: Baltimore MD 21224-6515 decitabine :: Treatment of sickle cell anemia :: 09-09-2002 :: Eisai Medical Research, Inc. :: 6611 Tributary Street :: Baltimore MD 21224-6515 Decitabine :: Treatment of chronic myelogenous leukemia. :: 08-03-1999 :: Eisai Medical Research, Inc. :: 6611 Tributary Street :: Suite 200 :: Baltimore MD 21224-6515deferiprone :: Treatment of Friedreich's ataxia. :: 31-07-2008 :: ApoPharma, Inc. :: 200 Barmac Drive :: CANADAdeferiprone :: Ferriprox :: Treatment of iron overload in patients with hematologic disorders requiring chronic transfusion therapy :: 12-12-2001 :: ApoPharma, Inc. A Division of :: Apotex Research Inc. :: Toronto, Canada M9L 1T9 :: CANADAdeferoxamine-starch conjugate :: Treatment of acute iron poisoning. :: 28-01-2005 :: Biomedical Frontiers, Inc. :: 1095 10th Avenue, SE :: Minneapolis MN 55414defibrotide :: For the prevention of hepatic veno-occlusive disease. :: 08-01-2007 :: Gentium SpA :: Piazza XX Settembre, 2 :: ITALYDefibrotide :: For the treatment of hepatic veno-occlusive disease :: 21-05-2003 :: Gentium SpA :: Piazza XX Settembre, 2 :: 22079 Villa Guardia (CO) :: ITALYDefibrotide :: Treatment of thrombotic thrombocytopenic purpura. :: 05-07-1985 :: Crinos International :: Via Belvedere 1 :: Villa Guardia, Italy 22079Dehydroepiandrosterone :: Treatment of systemic lupus erythematosus (SLE) and the reduction in the use of steroids in steroid-dependent SLE patients. :: 13-07-1994 :: Genelabs Technologies, Inc. :: 505 Penobscot Drive :: Redwood City CA 94063Dehydroepiandrosterone (DHEA) :: Fidelin :: Replacement therapy in individuals with adrenal insufficiency :: 19-08-2003 :: Paladin Labs, Inc. :: 6111 Royalmount Avenue, Suite 102 :: Montreal :: Quebec H4P 2T4 :: CANADADehydroepiandrosterone sulfate sodium :: Treatment of serious burns requiring hospitalization. :: 29-01-1997 :: Pharmadigm, Inc. :: 2401 Foothill Drive :: Salt Lake City UT 84109-1405 Dehydroepiandrosterone sulfate sodium :: To accelerate the re-epithelialization of donor sites in those hospitalized burn patients who must undergo autologous skin grafting. :: 28-01-1997 :: Pharmadigm, Inc. :: 2401 Foothill Drive :: Salt Lake City UT 84109-1405 Deslorelin :: Somagard :: 05-11-1987 :: Roberts Pharmaceutical Corp. :: Meridian Center II :: Four Industrial Way West :: Eatontown NJ 07724-2274Desmoglein 3 synthetic peptide (PI-0824) :: Treatment of pemphigus vulgaris :: 26-10-2004 :: Peptimmune, Inc. :: 64 Sidney Street :: Cambridge MA 02139-4170 Dexamethasone :: Posurdex :: For use in posterior segment drug delivery system in the treatment of idiopathic intermediate uveitis. :: 11-09-1998 :: Allergan :: 2525 Dupont Drive :: P. O. Box 19534 :: Irvine CA 92623-9534dexamethasone phosphate :: Treatment of corneal graft rejection. :: 02-12-2008 :: EyeGate Phardmaceuticals, Inc. :: 100 Beaver Street :: Waltham MA 02453dexanabinol :: For the attenuation or amelioration of the long-term neurological sequelae associated with moderate and severe traumatic brain injury :: 11-08-2004 :: Pharmos Corporation :: 99 Wood Avenue :: Suite 311 :: Iselin NJ 08830 dextran 1 :: Treatment of cystic fibrosis :: 21-03-2003 :: BCY LifeSciences Inc. :: 160 Eglinton Ave. East :: Suite 600 :: Toronto, Ontario M4P 3B :: CANADADextran 70 :: Dehydrex :: Treatment of recurrent corneal erosion unresponsive to conventional therapy. :: 05-03-1990 :: Holles Laboratories, Inc. :: 30 Forest Notch :: Cohasset MA 02025Dextran and deferoxamine :: Bio-Rescue :: Treatment of acute iron poisoning. :: 08-03-1991 :: Biomedical Frontiers, Inc. :: 1095 10th Avenue S.E. :: Minneapolis MN 55414Dextran sulfate (inhaled, aerosolized) :: Uendex :: For use as an adjunct to the treatment of cystic fibrosis. :: 05-10-1990 :: Kennedy & Hoidal, M.D.'s :: University Of Utah Medical Center :: 50 North Medical Drive, Room 4R240 :: Salt Lake City UT 84132 Dextran sulfate sodium :: Treatment of aquired immunodeficiency syndrome. :: 19-11-1987 :: Ueno Fine Chemicals Industry, Ltd. :: 2-31 Koraibashi, Higashi-ku :: Osaka 541 :: JAPANDHA-paclitaxel :: Taxoprexin :: Treatment of pancreatic cancer :: 25-09-2001 :: Luitpold Pharmaceuticals, Inc.. :: Clinical Research & Development :: 800 Adams Avenue :: Valley Forge PA 19403 DHA-paclitaxel :: Taxoprexin :: Treatment of adenocarcinoma of the stomach or lower esophagus :: 01-05-2003 :: Luitpold Pharmaceuticals, Inc. :: 800 Adams Avenue :: 1st Floor :: Valley Forge PA 19403 DHA-paclitaxel :: Taxoprexin :: Treatment of metastatic malignant melanoma :: 10-10-2002 :: Luitpold Pharmaceuticals, Inc.. :: Clinical Research and Development :: 800 Adams Avenue :: Valley Forge PA 19403 Dianeal peritoneal dialysis solution with 1.1% amino acids :: Nutrineal (Peritoneal Dialysis Solution with 1.1% Amino Acid :: For use as a nutritional supplement for the treatment of malnourishment in patients undergoing continuous ambulatory peritoneal dialysis. :: 11-06-1992 :: Baxter Healthcare Corporation :: 1620 Waukegan Road :: McGaw Park IL 60085Diaziquone :: Treatment of primary brain malignancies (grade III and IV astrocytomas). :: 10-11-1983 :: Warner-Lambert Company :: 2800 Plymouth Rd., P.O. Box 1047 :: Ann Arbor MI 48106Dideoxyinosine :: Treatment of acquired immunodeficiency syndrome. :: 22-06-1988 :: Bristol-Myers Squibb :: 2400 West Lloyd Expressway :: Evansville IN 47721Diethyldithiocarbamate :: Imuthiol :: Treatment of AIDS. :: 03-04-1986 :: Connaught Laboratories :: Route 611, P.O. Box 187 :: Swiftwater PA 18370diethylenetriaminepentaacetate (DPTA) :: For treatment of patients with known or suspected internal contamination with plutonium, americium or curium to increase the rates of elimination. :: 14-04-2004 :: CIS-US :: 10 DeAngelo Drive :: Bedford MA 01730Diethylnorspermine (DENSPM) :: Treatment for hepatocellular carcinoma :: 25-05-2004 :: Genzyme Corporation :: 153 Second Avenue :: Waltham MA 02451diferuloylmethane :: Treatment of cystic fibrosis :: 13-06-2003 :: Allertein Therapeutics, LLC :: 640 Sasco Hill Road :: Fairfield CT 06824difluprednate :: Durezol :: Treatment of endogenous and traumatic anterior uveitis and panuveitis. :: 30-09-2008 :: Sirion Therapeutics, Inc. :: 9314 E. Broadway Avenue :: Tampa FL 33619Digitoxin :: Treatment of cystic fibrosis :: 27-05-2005 :: Bette S. Pollard, LLC :: 11008 Lamplighter Lane :: Potomac MD 20854digitoxin :: Treatment of soft tissue sarcomas :: 18-10-2001 :: PrimeCyte, Inc. :: 130 Fifth Ave., N. :: Seattle WA 98109-4933 digitoxin :: Treatment of ovarian cancer :: 02-11-2001 :: PrimeCyte, Inc. :: 130 Fifth Ave., N. :: Seattle WA 98109-4933 Digoxin immune fab(ovine) :: Digidote :: Treatment of life-threatening acute cardiac glycoside intoxication manifested by conduction disorders, ectopic ventricular activity and (in some cases) hyperkalemia. :: 11-03-1985 :: Boehringer Mannheim Corp. :: 1301 Piccard Drive :: Rockville MD 20850dihydroartemisinin and piperaquine :: Eurartesim :: Treatment of uncomplicated malaria caused by "Plasmodium falciparum," Plasmodium vivax," Plasmodium malariae," or "Plasmodium ovale." :: 08-01-2007 :: Sigma-Tau Research, Inc. :: 9841 Washingtonian Blvd :: Suite 502 :: Gaithersburg MD 20878 Dihydrotestosterone :: Androgel -DHT :: Treatment of weight loss in AIDS patients with HIV-associated wasting. :: 05-02-1996 :: Besins Internaitonal, US Inc. :: 610 Herndon Parkway :: Suite 750 :: Herndon VA 20170 dimethyl sulfoxide :: For use in combination with antimicrobial drugs for the treatment of drug resistant tuberculosis :: 09-05-2008 :: Abela Pharmaceuticals, Inc. :: 21581 Midcrest Drive :: Lake Forest CA 92630Dimethyl sulfoxide :: Treatment of increased intracranial pressure in patients with severe, closed-head injury, also known as traumatic brain coma, for whom no other effective treatment is available. :: 22-11-1994 :: Abela Pharmaceuticals, Inc. :: 21581 Midcrest Drive :: Lake Forest CA 92630Dimethyl sulfoxide :: Treatment of cutaneous manifestations of scleroderma. :: 06-06-1986 :: Research Industries Corp. Dimethylsulfoxide :: Treatment of palmar-plantar erythrodysethesia syndrome. :: 06-04-1998 :: Cancer Technologies, Inc. :: 7301 East 22nd Street :: Suite 10E :: Tucson AZ 85710 Dimethylsulfoxide :: Topical treatment for the prevention of soft tissue injury following extravastion of cytotoxic drugs. :: 15-04-1997 :: Cancer Technologies, Inc. :: 7301 East 22nd Street :: Suite 10E :: Tucson AZ 85710 Dipalmitoylphosphatidylcholine /phosphatidylglycerol :: ALEC :: Prevention and treatment of neonatal respiratory distress syndrome. :: 28-07-1988 :: Forum Products, Inc. :: 33 Flying Point Road :: Southampton NY 11968diphenylcyclopenone :: Treatment of chronic severe forms of alopecia areata (Alopecia Totalis [AT]/Alopecia Universalis [AU]) :: 13-06-2003 :: Lloyd E. King, Jr. :: 1900 Patterson Street :: Suite 104 :: Nashville TN 37203 Disaccharide tripeptide glycerol dipalmitoyl :: Immther :: Treatment of pulmonary and hepatic metastases in patients with colorectal adenocarcinoma. :: 01-03-1990 :: ImmunoTherapeutics, Inc. :: 3505 Riverview Circle :: Moorhead MN 56560Disodium clodronate :: Treatment of hypercalcemia of malignancy. :: 16-06-1993 :: Discovery Experimental & Development, Inc. :: 29949 S.R. 54 West :: Wesley Chapel FL 33543Disodium clodronate tetrahydrate :: Bonefos :: Treatment of increased bone resorption due to malignancy. :: 05-03-1990 :: Anthra Pharmaceuticals, Inc. :: 103 Carnegie Center, Suite 102 :: Princeton NJ 08540Disodium silibinin dihemisuccinate :: Legalon :: Treatment of hepatic intoxication by Amanita phalloides (mushroom poisoning). :: 10-07-1986 :: Pharmaquest Corporation :: 4470 Redwood Highway :: San Rafael CA 94903D-mannitol and L-proline :: Prodarsan(r) :: Treatment of Cockayne syndrome :: 20-04-2009 :: DNage B.V. :: Darwinweg 24 :: NETHERLANDSDMP 777 :: Therapeutic management of patients with lung disease attributable to cystic fibrosis. :: 04-06-1996 :: DuPont Pharmaceuticals Company :: Chestnut Run, Maple Run :: Centre Rd. :: Wilmington DE 19805 DNA plasmid vector expressing human IL-12 gene :: Treatment of ovarian cancer. :: 04-04-2005 :: Expression Genetics, Inc. :: 2215 Mock Road :: Huntsville AL 35801DNA-lipid complex (DMRIE/DOPE)/plasmid vector (VCL-1102, Vical) expressing human interleukin-2 :: Leuvectin :: Treatment of renal cell carcinoma. :: 28-04-2000 :: Vical Incorporated :: 9373 Towne Center Dr. :: Suite 100 :: San Diego CA 92121-3088DNP-Modified autologous tumor vaccine :: O-Vax :: Adjuvant therapy for the treatment of ovarian cancer :: 21-09-2000 :: AVAX Technologies, Inc. :: 9200 Indian Creek Parkway :: Building 9, Suite 200 :: Overland Park KS 66210 docosahexanoic acid-paclitaxel :: Taxoprexin :: Treatment of hormone-refractory prostate cancer. :: 05-03-2001 :: Luitpold Pharmaceuticals, Inc. :: 800 Adams Avenue :: 1st Floor :: Valley Forge PA 19403 Doripenem :: Treatment of bronchopulmonary infection in patients with cystic fibrosis who are colonized with Pseudomonas aeruginosa or Burkholderia cepacia. :: 16-07-2004 :: Johnson & Johnson Pharmaceutical Research & Dev. :: 920 US Highway 202 :: P. O. Box 300 :: Raritan NJ 08869 Dovitinib :: Treatment of multiple myeloma :: 03-10-2006 :: Novartis Pharmaceuticals Corporation :: One Health Plaza :: East Hanover NJ 07936-1080 Doxorubicin HCl with pluronic L-61 and pluronic F-127 :: Treatment of esophageal carcinoma :: 07-10-2005 :: Supratek Pharma Inc. :: 215Bouchard Blvd :: Dorval :: Quebec H9S 1A9 :: CANADAdoxorubicin PIHCA nanoparticles :: Doxorubicin Transdrug :: Treatment of hepatocellular carcinoma :: 14-03-2005 :: BioAlliance Pharma :: 59, Bd Gal Martial Valin – 75015 :: Paris :: FRANCEdoxorubicin with pluronics F-127 and L-61 :: Treatment of gastric cancer :: 20-02-2008 :: Supratek Pharma, Inc. :: 215 Bouchard Blvd :: Dorval, Quebec H9S 1A9 :: CANADAD-peptide of the sequence AKRHHGYKRKFH – NH2 :: PulmaDex :: Treatment of cystic fibrosis :: 23-10-2002 :: Demegen, Inc. :: 100 Technology Drive :: Suite 440 B :: Pittsburgh PA 15219 D-Phe-Cys-Tyr-D-Trp-Lys-Cys-Thr-Nh2 (disulfide bridge: 2-6) acetate :: Treatment of melanoma, stages IIb through IV :: 19-03-2009 :: Thallion Pharmaceuticals, Inc. :: 7150 Alexander-Fleming :: H4S 2C8 :: Montreal :: CANADAdroxidopa :: Treatment of neurogenic symptomatic orthostatic hypotension in patients with primary autonomic failure, dopamine-beta-hydroxylase deficiency, and nondiabetic autonomic neuropathy. :: 17-01-2007 :: Chelsea Therapeutics, Inc. :: 13950 Ballantyne Corporate Place :: Charlotte NC 28277Duramycin :: Treatment of cystic fibrosis. :: 11-12-1997 :: Lantibio, Inc. :: 100 Europa Drive :: Suite 421 :: Chapel Hill NC 27517 Dynamine :: Treatment of hereditary motor and sensory neuropathy type I (Charcot-Marie-Tooth disease). :: 16-10-1991 :: Mayo Foundation :: 200 First Street Southwest :: Rochester MN 55905Dynamine :: Treatment of Lambert Eaton myasthenic syndrome. :: 05-02-1990 :: Mayo Foundation :: 200 First Street Southwest :: Rochester MN 55905ecallantide :: Kalbitor :: Treatment of angioedema :: 04-02-2003 :: Dyax Corp :: 300 Technology Square :: Cambridge MA 02139eculizumab :: Soliris(r) :: Treatment of atypical hemolytic uremic syndrome :: 29-04-2009 :: Alexion Pharmaceuticals, Inc. :: 352 Knotter Drive :: Cheshire CT 06410eculizumab :: Treatment of idiopathic membranous glomerular nephropathy :: 05-03-2001 :: Alexion Pharmaceuticals, Inc. :: 352 Knotter Drive :: Cheshire CT 06410Eculizumab :: Treatment of dermatomyositis :: 21-09-2000 :: Alexion Pharmaceuticals, Inc. :: 352 Knotter Drive :: Cheshire CT 06410Edotreotide :: OctreoTher :: Treatment of somatostatin receptor-positive neuroendocrine gastroenteropancreatic tumors :: 28-07-2005 :: Novartis Pharmaceuticals Corp. :: 59 Route 10/Bldg 122/N142 :: One Health Plaza :: East Hanover NJ 07936-1080efaproxiral :: Adjunct to whole brain radiation therapy for the treatment of brain metastases in patients with breast cancer :: 28-07-2004 :: Allos Therapeutics, Inc. :: 11080 CirclePoint Road :: Suite 200 :: Westminster CO 80020 Eflornithine :: Treatment of anaplastic glioma :: 29-09-2006 :: VBL Pharmaceuticals, Inc. :: 216 Robin Way :: Menlo Park CA 94025Eflornithine HCl :: Ornidyl :: Treatment of Pneumocystis carinii pneumonia in AIDS patients. :: 18-04-1986 :: Marion Merrell Dow, Inc. :: P.O. Box 9627 :: Kansas City MO 64134Elcatonin :: Intrathecal treatment of intractable pain. :: 25-09-1995 :: Innapharma, Inc. :: 10 Mountainview Road :: Upper Saddle River NJ 07458Enadoline hydrochloride :: Treatment of severe head injury. :: 28-01-1997 :: Warner-Lambert Company :: Parke-Davis Pharmaceutical Research Division :: 2800 Plymouth Road :: Ann Arbor MI 48105 Encapsulated porcine islet preparation :: BetaRx :: Treatment of type I diabetic patients who are already on immunosuppression. :: 05-07-1995 :: VivoRx :: 2825 Santa Monica Blvd. :: 2nd Floor :: Santa Monica CA 90404-2429eniluracil :: Treatment of hepatocellular carcinoma :: 15-12-2005 :: Adherex Technologies, Inc. :: 4620 Creekstone Drive :: Research Triangle Park :: Durham NC 27703 Enisoprost :: For use in organ transplant patients to diminish the nephrotoxicity induced by cyclosporine. :: 20-10-1989 :: G.D. Searle & Company :: 4901 Searle Parkway :: Skokie IL 60077Enisoprost :: For use with cyclosporine in organ transplant recipients to reduce acute transplant rejection. :: 20-10-1989 :: G.D. Searle & Company :: 4901 Searle Parkway :: Skokie IL 60077Enteric-coated cysteamine :: Treatment of cystinosis :: 24-10-2006 :: Raptor Therapeutics, Inc. :: 9 Commercial Boulevard :: Suite 200 :: Novato CA 94949-6118enzastaurin :: Treatment of diffuse large B-cell lymphoma :: 04-03-2009 :: Eli Lilly and Company :: Lilly Corporate Center :: Indianapolis IN 46285Enzastaurin :: Treatment of glioblastoma multiforme :: 19-09-2005 :: Eli Lilly and Company :: Lilly Corporate Center :: Indianapolis IN 46285Epidermal growth factor (human) :: For acceleration of corneal epithelial regeneration and the healing of stromal tissue in the condition of non-healing corneal defects. :: 05-10-1987 :: Chiron Vision :: 500 Iolab Drive :: Claremont CA 91711Epidermal growth factor (human) :: For promotion of cutaneous wound healing in extreme burn treatment protocols. :: 06-03-1985 :: Ethicon, Inc. :: P.O. Box 151 :: Somerville NJ 08876Epoetin alfa :: Treatment of myelodysplastic syndrome. :: 20-12-1993 :: Johnson & Johnson Pharmaceutical Research & Dev., :: 920 U.S. Highway :: Route 202, P.O. Box 300 :: Raritan NJ 08869-0602Epoetin alpha :: Procrit :: Treatment of anemia associated with end stage renal disease. :: 27-08-1987 :: R. W. Johnson Pharmaceutical Research Institute :: Route 202 South :: P.O. Box 300 :: Raritan NJ 08869 Epoetin alpha :: Procrit :: Treatment of anemia of prematurity in preterm infants. :: 21-07-1988 :: Ortho Biotech Oncology Research & Development :: Johnson & Johnson Pharmaceutical R & D, LLC :: 920 US Highway 202 :: Raritan NJ 08869-0602Epoetin alpha :: Procrit :: Treatment of HIV associated anemia related to HIV infection or HIV treatment. :: 07-03-1989 :: R. W. Johnson Pharmaceutical Research Institute :: Route 202, P.O. Box 300 :: Raritan NJ 08869Epoetin beta :: Marogen :: Treatment of anemia associated with end stage renal disease. :: 22-10-1987 :: Chugai-USA, Inc. :: 3780 Hawthorn Court :: Waukegan IL 60087Epoprostenol :: Flolan :: Replacement of heparin in patients requiring hemodialysis and who are at increased risk of hemorrhage. :: 29-03-1984 :: Glaxo Wellcome Inc. :: 5 Moore Drive :: Research Triangle Park NC 27709Epoprostenol :: Cycloprostin :: Replacement of heparin in patients requiring hemodialysis and who are at increased risk of hemorrhage. :: 29-10-1984 :: Upjohn Company :: 301 Henrietta Street :: Kalamazoo MI 49001epratuzumab :: Treatment of acute lymphoblastic leukemia :: 30-09-2008 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950epratuzumab :: LymphoCIDE :: Treatment of non-Hodgkin's lymphoma. :: 13-07-1998 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Eprodisate :: Fibrillex :: Treatment of secondary amyloidosis :: 06-04-1999 :: Neurochem, Inc. :: 7220 Frederick Banting, Suite 100 :: Saint-Laurent :: Quebec H4S 2A1 :: CANADAEpstein Barr Virus specific cytotoxic T lymphocytes :: Prevention and treatment of EBV-post transplant lymphoproliferative disease after hematopoietic stem cell transplant or solid organ transplant. :: 27-12-2006 :: Center for Cell and Gene Therapy :: Feigin Center :: Suite 1120 :: Houston TX 77030-2399Erlotinib Hydrochloride :: Tarceva :: Treatment of malignant gliomas :: 18-07-2003 :: Genentech, Inc :: 1 DNA Way :: South San Francisco CA 94080-4990 Erwinia L-asparaginase :: Erwinase :: Treatment of acute lymphocytic leukemia. :: 30-07-1986 :: EUSA Pharma (US), Inc. :: 1980 South Easton Road :: Suite 250 :: Doylestown PA 18901 Erwinia L-asparaginase :: For use as an alternative to E. coli asparaginase in those situations where repeat courses of asparaginase therapy for acute lymphoblastic leukemia are required or where allergic reactions force the discontinuance of the E. coli preparation. :: 25-01-1985 :: Lyphomed, Inc. Erythropoietin (human, recombinant) :: Treatment of anemia associated with end stage renal disease. :: 19-11-1987 :: Organon Teknika Corporation Erythropoietin (recombinant human) :: Treatment of anemia associated with end stage renal disease. :: 19-08-1987 :: McDonnell Douglas Corp :: P.O. Box 516, 107/2 MS10 :: St. Louis MO 63166Estradiol Gel :: EstroGel (r) :: Estrogen replacement therapy in females with Turner syndrome :: 31-10-2006 :: Ascend Therapeutics, Inc. :: 607 Herndon Parkway :: Suite 110 :: Herndon VA 21070 Etanercept :: Enbrel :: Treatment of Wegener's granulomatosis. :: 06-04-1999 :: Immunex Corporation :: 51 University Street :: Seattle WA 98101-2936 Ethanol gel :: Treatment of congenital lymphatic malformations :: 13-03-2006 :: Orfagen :: Parc Technologique du Canal :: 31521 Ramonville Saint Agne Cedex :: FRANCEEthanol gel :: Treatment of congenital venous malformations :: 29-03-2006 :: Orfagen :: Parc Technologique du Canal :: 31521 Ramonville Saint Agne Cedex :: FRANCEEthinyl Estradiol, USP :: Treatment of Turner's syndrome. :: 22-06-1988 :: Bio-Technology General Corp. :: 70 Wood Avenue, South :: Iselin NJ 08830Ethiofos :: Use as a chemoprotective agent for cisplatin and cyclophosphamide in the treatment of ovarian cancer. :: 01-08-1989 :: U.S. Bioscience :: 100 Front Street :: West Conshohocken PA 19428Ethyl eicosapentaenoate :: Treatment of Huntington's disease. :: 06-04-2000 :: Laxdale Ltd. :: Kings Park House, Laurelhill Business Park :: Polmaise Road, Stirling FK7 9JQ :: UNITED KINGDOMEtidronate disodium :: Didronel IV infusion :: Prevention of degenerative metabolic bone disease occurring in patients who require long term (6 months or greater) total parenteral nutrition. :: 02-05-1991 :: MGI Pharma, Inc. :: 6300 West Old Shakoppe Rd. :: Suite 110 :: Bloomington MN 55438-2318Etidronate disodium :: Didronel IV Infusion :: Treatment of degenerative metabolic bone disease occurring in patients who require long term (6 months or greater) total parenteral nutrition. :: 02-05-1991 :: MGI Pharma, Inc. :: 6300 West Old Shakoppe Rd. :: Suite 110 :: Bloomington MN 55438-2318Etiocholanedione :: Treatment of Prader-Willi syndrome. :: 07-05-1996 :: SuperGen, Inc. :: Two Annabel Lane, Suite 220 :: San Ramon CA 94583Etiocholanedione :: Treatment of aplastic anemia. :: 03-11-1995 :: SuperGen, Inc. :: Two Annabel Lane, Suite 220 :: Suite 10 :: San Ramon CA 94583 everolimus :: Treatment of gastroenteropancreatic neuroendocrine tumors :: 14-02-2008 :: Novartis Pharmaceuticals Corporation :: One Health Plaza :: East Hanover NJ 07936-1080 Ex vivo cultured adult human mesenchymal stem cells :: Prochymal :: Treatment of acute graft versus host disease :: 14-12-2005 :: Osiris Therpeutics, Inc. :: 2001 Aliceanna Street :: Baltimore MD 21231-3043 Exisulind :: For the suppression and control of colonic adenomatous polyps in the inherited disease adenomatous polyposis coli. :: 14-02-1994 :: OSI Pharmaceuticals, Inc. :: 58 South Service Road :: Suite 110 :: Melville NY 11747 Factor XIII [A2] homodimer, recombinant DNA origin :: Treatment of congenital FXIII deficiency :: 21-05-2003 :: Novo Nordisk Pharmaceuticals, INc. :: 100 College Road West :: Princeton NJ 08540Factor XIII [A2} homodimer, recombinant DNA origin :: For the prophylaxis of bleeding associated with congential FXIII deficiency :: 06-11-2003 :: Novo Nordisk, Inc. :: 100 College Road West :: Princeton NJ 08540factor XIII concentrate (human), pasteurized :: Fibrogammin P :: Treatment of congenital factor XIII deficiency. :: 16-01-1985 :: CSL Behring L.L.C. :: 1020 First Ave. :: PO Box 61501 :: King of Prussia PA 19406-0901Factor XIII, recombinant :: Treatment of congenital factor XIII deficiency. :: 22-04-1993 :: Zymogenetics, Inc. :: 4225 Roosevelt Way :: Seattle WA 98105Fampridine :: Neurelan :: Relief of symptoms of multiple sclerosis. :: 02-06-1987 :: Acorda Therapeutics :: 15 Skyline Dr. :: Hawthorne NY 10532Fampridine :: Neurelan :: Treatment of chronic, incomplete spinal cord injury. :: 02-06-1997 :: Acorda Therapeutics, Inc. :: 15 Skyline Dr. :: Hawthorne NY 10532Fenobam hydrochloride :: Treatment of fragile X syndrome :: 20-11-2006 :: Neuropharm, Ltd. :: Fetcham Park House :: Leatherhead, Surrey KT22 9HD :: UNITED KINGDOMfenretinide :: Treatment of Ewing's sarcoma family of tumors. :: 01-02-2007 :: Cancer Research UK :: 61 Lincoln's Inn Fields :: London WC2A 3PX :: UNITED KINGDOMFenretinide :: Treatment of neuroblastoma :: 05-10-2005 :: USC-CHLA Institute for Pediatric Clinical Research :: Childrens Hospital Los Angeles :: 4650 Sunset Blve, MS 55 :: Los Angeles CA 90027 ferric hexacyanoferrate (II) "Prussian Blue" :: Treatment of patients with known or suspected internal contamination with radioactive or non-radioactive cesium or thallium :: 26-06-2003 :: Degussa AG :: Weissfrauenstr.9 :: D-60287 :: Frankfurt :: GERMANYFIAU :: Adjunctive treatment of chronic active hepatitis B. :: 24-07-1992 :: Oclassen Pharmaceuticals, Inc. :: 100 Pelican Way :: San Rafael CA 94901Fibrinogen (human) :: For the control of bleeding and prophylactic treatment of patients deficient in fibrinogen. :: 23-08-1995 :: Alpha Therapeutic Corporation :: 5555 Valley Boulevard :: Los Angeles CA 90032Fibronectin (human plasma derived) :: Treatment of non-healing corneal ulcers or epithelial defects which have been unresponsive to conventional therapy and the underlying cause has been eliminated. :: 05-09-1988 :: Melville Biologics, Inc. :: 310 East 67th Street :: New York NY 10021Fibronectin (plasma derived) :: Treatment of non-healing corneal ulcers or epithelial defects which are unresponsive to conventional therapy and for which any infectious cause of the defect has been eliminated. :: 05-12-1988 :: Chiron Vision :: 9342 Jeronimo Road :: Irvine CA 92718Filgrastim :: Neupogen :: Treatment of myelodysplastic syndrome. :: 30-08-1990 :: Amgen, Inc. :: 1840 Dehavilland Drive :: Thousand Oaks CA 91320Filgrastim :: Neupogen :: Treatment of patients with AIDS who, in addition, are afflicted with cytomegalovirus retinitis and are being treated with ganciclovir. :: 03-09-1991 :: Amgen, Inc. :: One Amgen Center Dr. :: Thousand Oaks CA 91320-1799 Floxuridine, FUDR :: Intraperitoneal treatment of gastric cancer. :: 22-12-2004 :: Franco Muggia, M.D. :: 160 East 34th Street :: New York NY 10016Fludarabine phosphate :: Fludara :: Treatment and management of patients with non-Hodgkins lymphoma. :: 18-04-1989 :: Berlex Laboratories, Inc. :: 15049 San Pablo Avenue :: P.O. Box 4099 :: Richmond CA 94804-0099Flumecinol :: Zixoryn :: Treatment of hyperbilirubinemia in newborn infants unresponsive to phototherapy. :: 15-01-1985 :: Farmacon, Inc. :: Post House, Suite 213 :: 1720 Post Road East :: Westport CT 06880-5643Flunarizine :: Sibelium :: Treatment of alternating hemiplegia. :: 06-01-1986 :: Janssen Research Foundation :: P.O. Box 200 :: Titusville NJ 08560 Fluorouracil :: Adrucil :: For use in combination with leucovorin for therapy of metastatic adenocarcinoma of the colon and rectum. :: 06-02-1989 :: Lederle Laboratories :: Division of American Cyanamid Company :: 401 N. Middletown Road :: Pearl River NY 10965 Fluorouracil :: For use in combination with interferon alpha-2a, recombinant, for the treatment of esophageal carcinoma. :: 27-10-1989 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110-1199 Fluorouracil :: For use in combination with interferon alpha-2a, recombinant, for the treatment of advanced colorectal carcinoma. :: 18-04-1990 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110-1199 Fluorouracil :: Treatment of glioblastoma multiforme. :: 29-06-2000 :: Ethypharm SA :: 194 Bureaux de la Colline – Batiment D :: 92213 Saint-Cloud Cedex :: Fluoxetine :: Prozac :: Treatment of autism. :: 30-04-1999 :: Neuropharm, Ltd. :: Felcham Park House :: Lower Road, Leatherhead :: UNITED KINGDOMFluoxetine :: Prozac :: Treatment of body dysmorphic disorder in children and adolescents :: 14-04-2004 :: Hollander, Eric MD :: The Mount Sinai School of Medicine :: One Gustave L. Levy Place :: New York NY 10029-6574fosfomycin/tobramycin :: Treatment of pulmonary infections associated with cystic fibrosis. :: 28-11-2008 :: Gilead Sciences, Ince. :: 2025 First Avenue :: Seattle WA 98121Fructose-1,6-diphosphate :: Cordox :: Treatment of painful vaso-occlusive episodes associated with sickle cell disease. :: 29-05-1998 :: Questcor Pharmaceuticals, Inc. :: 3260 Whipple Road :: Union City CA 94587-1217 Full Phosphorothioate Antisense Oligonucleotide against EWS-Fli-1 nanoparticles :: Treatment of Ewing's sarcoma :: 22-09-2008 :: The Cure Our Children Foundation :: 1730 Michael Lane :: Pacific Palisades CA 90272-2037 Fully Human Anti-MCP-1/CCL2 Monoclonal Antibody :: Treatment of idiopathic pulmonary fibrosis. :: 08-11-2007 :: Centocor, Inc. :: 200 Great Vallley Parkway :: Malvern PA 19355-1307 Fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1 :: Treatment of X-linked hypohidrotic ectodermal dysplasia :: 11-01-2006 :: Topo Target A/S :: Symbion Science Park :: Fruebjergvej 3 :: DENMARKG17DT Immunogen :: Treatment of gastric cancer :: 18-07-2002 :: Receptor BioLogix, Inc. :: 1140 Veterans Blvd. :: Suite A :: South San Francisco CA 94080 G17DT Immunogen :: Treatment of adenocarcinoma of the pancreas :: 10-07-2002 :: Receptor BioLogix, Inc. :: 1140 Veterans Blvd. :: Suite A :: South San Francisco CA 94080 Gabapentin :: Neurontin :: Treatment of amyotrophic lateral sclerosis. :: 05-07-1995 :: Warner-Lambert Company :: Parke-Davis Pharmaceutical Research Division :: 2800 Plymouth Road :: Ann Arbor MI 48105 Gamma hydroxybutyrate :: Treatment of narcolepsy and the auxiliary symptoms of cataplexy, sleep paralysis, hypnagogic hallucinations and automatic behavior. :: 03-12-1987 :: Biocraft Laboratories, Inc. :: 18-01 River Road :: Fair Lawn NJ 07410Gamma-hydroxybutyric acid :: Treatment of narcolepsy and the auxiliary symptoms of cataplexy, sleep paralysis, hypnagogic hallucinations, and automatic behavior. :: 22-01-1985 :: Sigma Chemical Company Gammalinolenic acid :: Treatment of juvenile rheumatoid arthritis. :: 27-07-1994 :: Zurier, Robert B. M.D. :: University of Massachusetts Medical Center :: 55 Lake Avenue :: Worcester MA 01655 Ganaxolone :: Treatment of infantile spasms. :: 25-05-1994 :: Marinus Pharmaceuticals, Inc. :: 21 Business Park Drive :: Branford CT 06405Ganciclovir :: Virgan :: Treatment of acute herpetic keratitis (dendritic and geographic ulcers) :: 22-03-2007 :: Sirion Therapeutics, Inc. :: 9314 East Broadway Avenue :: Tampa FL 33619Gancyclovir :: Treatment of severe human cytomegalovirus infections in specific immunosuppressed patient populations. :: 07-06-1985 :: Burroughs Wellcome Company :: 3030 Cornwallis Road :: P.O. Box 12700 :: Research Triangle Park NC 27709 Gangliosides as sodium salts :: Cronassial :: Treatment of retinitis pigmentosa. :: 17-11-1988 :: Fidia Pharmaceutical Corp. :: 1401 Eye Street, N.W. Suite 900 :: Washington DC 20005Gavilimomab :: Acute graft-versus-host disease (aGVHD) :: 20-11-2000 :: Amgen :: One Amgen Center Drive :: Mail Stop 17-2-A :: Thousand Oaks CA 91320-1799gene encoding chimeric CD40 ligand :: Treatment of chronic lymphocytic leukemia :: 04-02-2009 :: Memgen, LLC :: 7557 Rambler Road :: Dallas TX 75231Gene plasmid hVEGF165 driven by human cytomegalovirus, and [2,3-bis(oleoyl)propyl]trimethyl ammonium and dioleoyl phosphatidyl ethanolamine :: Trinam :: Prevention of complications due to neointimal hyperplasia disease in certain vascular anastomoses. :: 24-10-2000 :: Ark Therapeutics Ltd. :: 1 Fitzroy Mews :: London :: UNITED KINGDOMgenetically engineered herpes simplex virus (G207) :: Tretament of malignant glioma :: 29-04-2002 :: MediGene, Inc. :: 10650 Scripps Ranch Blvd. :: Suite 230 :: San Diego CA 92131 Geneticin :: Treatment of amoebiasis. :: 06-06-2005 :: ProcesScience, Inc (PSI) :: 117 Woodberry Lane :: Fayetteville NY 13066Gentamicin impregnated PMMA beads on surgical wire :: Septopal :: Treatment of chronic osteomyelitis of post-traumatic, postoperative, or hematogenous origin. :: 31-01-1991 :: Lipha Pharmaceuticals, Inc. :: 9 West 57th Street :: Suite 3825 :: New York NY 10019-2701Gentamicin liposome injection :: Maitec :: Treatment of disseminated Mycobacterium avium-intracellulare infection. :: 10-07-1990 :: Liposome Company, Inc. :: One Research Way :: Princeton NJ 08540glatiramer acetate :: Copaxone :: Treatment of amyothrophic lateral sclerosis (ALS). :: 14-11-2007 :: Teva Neurosciences, Inc. :: P. O. Box 1005 :: Horsham PA 19044-8005 Glatiramer acetate for injection :: Copaxone :: Treatment of primary-progressive multiple sclerosis :: 05-06-2001 :: TEVA Pharmaceuticals, USA :: 1090 Horsham Road :: North Wales PA 19454glucarpidase :: Voraxaze :: Treatment of patients at risk of methotrexate toxicity :: 19-08-2003 :: Protherics, Inc. :: 5214 Maryland Way, Suite 405 :: Brentwood TN 37027glufosfamide :: For treatment of pancreatic cancer. :: 18-09-2006 :: Threshold Pharmaceuticals, Inc. :: 1300 Seaport Blvd. :: Redwood City CA 94063Glycafilin :: "Prevention of delayed graft function after solid organ transplantation" :: 22-08-2008 :: ProtAffin Biotechnologie AG :: Impulszentrum Graz – West :: A-8020 Graz :: AUSTRIAGlyceol :: To decrease intracranial hypertension and/or alleviate cerebral edema in patients who may benefit from osmotherapy. :: 22-02-1990 :: Chugai Pharmaceutical Co., Ltd. Glyceryl tri (4-phenylbutyrate) :: Treatment of spinal muscular atrophy :: 24-05-2005 :: Ucyclyd Pharma, Inc :: Subsidiary of Medicis Pharmaceutical Corporation :: 8125 N. Hayden Rd. :: Scottsdale AZ 85258 glyceryl tri (4-phenylbutyrate) :: Maintenance treatment of patients with deficiencies in enzymes of the urea cycle :: 27-04-2009 :: Hyperion Therapeutics, Inc. :: 601 Gateway Blvd. :: Suite 200 :: South San Francisco CA 94080 Glyceryl trioleate and glyceryl trierucate :: Treatment of adrenoleukodystrophy. :: 14-02-1995 :: Moser, Hugo W. M.D. :: Johns Hopkins University :: Kennedy Krieger Institute, 707 North Broadway :: Baltimore MD 21205 Glycopyrrolate :: Treatment of pathologic (chronic moderate to severe) drooling in pediatric patients :: 09-06-2006 :: Sciele Pharma, Inc. :: Five Concourse Parkway :: Suite 1800 :: Atlanta GA 30328 GMI-1070 :: Treatment of vaso-occlusive crisis in patients with sickle cell disease. :: 17-02-2009 :: GlycoMimetics, Inc. :: 101 Orchard Ridge Drive :: Gaithersburg MD 20878GNE Lipoplex :: Treatment of hereditary inclusion body myopathy-2 :: 13-11-2008 :: Gradalis, Inc. :: 2545 Golden Bear Drive :: Carrollton TX 75006Golimumab :: Treatment of chronic sarcoidosis :: 02-11-2004 :: Centocor, Inc. :: 200 Great Valley Parkway :: Malvern PA 19355-1307 Gossypol :: Treatment of cancer of the adrenal cortex. :: 22-10-1990 :: Reidenberg, Marcus M. M.D. :: The New York Hospital – Cornell Medical Center :: 525 East 68th Street, Box 70 :: New York NY 10021 Gp100 adenoviral gene therapy :: Treatment of metastatic melanoma. :: 25-03-1997 :: Genzyme Corporation :: 500 Kendall Street :: Cambridge MA 02142granulocyte macrophage colony stimuling factor :: Treatment of cystic fibrosis :: 27-08-2008 :: DrugRecure Aps :: Scion DTU :: Boge alle 5, 1,tv :: DENMARKGranulocyte macrophage-colony stimulating factor :: Leucomax :: Treatment of severe thermal injuries in patients with greater than 40% full or partial thickness burns. :: 06-06-1989 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Granulocyte macrophage-colony stimulating factor :: Leucomax :: Treatment of chronic lymphocytic leukemia to increase granulocyte count. :: 04-05-1990 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Granulocyte macrophage-colony stimulating factor :: Leucomax :: Treatment of myelodysplastic syndrome. :: 07-08-1989 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Granulocyte macrophage-colony stimulating factor :: Leucomax :: Treatment of neutropenia associated with bone marrow transplants. :: 12-12-1989 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Granulocyte macrophage-colony stimulating factor :: Leucomax :: Treatment of neutropenia due to hairy cell leukemia. :: 03-05-1990 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Group B streptococcus immune globulin :: Treatment of neonates for disseminated group B streptococcal infection. :: 08-05-1990 :: North American Biologicals, Inc. :: 12280 Wilkins Avenue :: Rockville MD 20852Growth hormone releasing factor :: For the long-term treatment of children who have growth failure due to a lack of adequate endogenous growth hormone secretion. :: 07-08-1989 :: Valeant Pharmaceuticals International :: One Enterprise Way :: Aliso Viejo CA 92656 :: Guanethidine monosulfate :: Ismelin :: Treatment of moderate to severe reflex sympathetic dystrophy and causalgia. :: 06-01-1986 :: Novartis Pharmaceuticals Corporation :: 59 Route 10 :: East Hanover NJ 07936-1080 Guanfacine :: Tenex :: Treatment of fragile X syndrome. :: 05-08-1999 :: Watson Laboratories, Inc. :: 311 Bonnie Circle :: PO Box 1900 :: Corona CA 91718-1900Gusperimus :: Spanidin :: Treatment of acute renal graft rejection episodes. :: 27-06-1996 :: Bristol-Myers Squibb Pharmaceutical Research Institute :: 5 Research Parkway :: P.O. Box 5100 :: Wallingford CT 06492-7660Halofuginone :: Stenorol :: Treatment of systemic sclerosis. :: 07-02-2000 :: Collgard Biopharmaceuticals Ltd. :: Textile House, 2 Koifman St. :: Tel-Aviv 68012 :: ISRAELheat killed Mycobacterium w immunomodulator :: CADI Mw :: Active tuberculosis :: 03-09-2004 :: Cadila Pharmaceuticals Limited, Inc. :: 9801 Washingtonian Blvd :: Suite 220 :: Gaithersburg MD 20878 heat killed mycobacterium w immunomodulator :: CADI Mw :: Adjuvant to multi-drug therapy in the management of multibacillary leprosy :: 21-11-2002 :: CPL, Inc. :: 16020 Swingley Ridge Road :: Suite 145 :: Chesterfield MO 63017 Heme arginate :: Normosang :: Treatment of symptomatic stage of acute porphyria. :: 10-03-1988 :: Orphan Europe :: Immeuble Le Guillaumet :: 92046 Paris La Defense :: FRANCEHeme arginate :: Normosang :: Treatment of myelodysplastic syndromes. :: 01-03-1994 :: Orphan Europe :: Immeuble Le Guillaumet :: 70 avenue du General de Gaulle, :: 92056 Paris La Defense :: FRANCEHemin and zinc mesoporphyrin :: Hemex :: Treatment of acute porphyric syndromes. :: 20-12-1993 :: Bonkovsky, Herbert L. M.D. :: University Of Massachusetts Medical Center :: 55 Lake Avenue North :: Worcester MA 01655 Hemoximer (pyridoxalated hemoglobin polyoxyethylene) :: Treatment of cardiogenic shock :: 18-12-2007 :: Apex Bioscience, Inc. :: 109 Conner Drive :: ` :: Chapel Hill NC 27514 Heparin :: Treatment of cystic fibrosis :: 03-11-2005 :: Vectura Group, Inc. :: 1 Prospect West :: Wiltshire SN14 6FH :: UNITED KINGDOMHeparin sodium :: Treatment of cystic fibrosis :: 29-06-2006 :: Ockham Biotech Limited :: Manor Farm :: 98 Swanwick Lane :: UNITED KINGDOMHeparin-binding epidermal growth factor-like growth factor :: Prevention and treatment of necrotizing enterocolitis (NEC) in preterm infants with birth weight less than 1,500 grams :: 18-09-2006 :: Trillium Therapeutics, Inc. :: 96 Skyway Avenue :: M9W 4Y4 :: CANADAHepatitis B immune globulin intravenous (human) :: Nabi-HB :: Prophylaxis against hepatitis B virus reinfection in liver transplant patients. :: 08-03-1995 :: Biotest Pharmaceuticals Corporation :: 5800 Park of Commerce Blvd., NW :: Boca Raton FL 33487Hepatitis C virus immune globulin (human) :: Civacir(tm) :: Prophylaxis of hepatitis C infection in liver transplant recipients. :: 14-11-2002 :: Biotest Pharmaceuticals Corporation :: 5800 Park of Commerce Blvd, NW :: Boca Raton FL 33487HepeX-B :: For the prevention of hepatitis B virus (HBV) reinfection in patients who have received a liver transplantation :: 15-07-2003 :: Cubist Pharmaceuticals :: 65 Hayden Avnue :: Lexington MA 02421Herpes simplex virus gene :: Treatment of primary and metastatic brain tumors. :: 16-10-1992 :: Genetic Therapy, Inc. :: 938 Clopper Road :: Gaithersburg MD 20878Histamine :: Maxamine :: For use as an adjunct to cytokine therapy in the treatment of malignant melanoma. :: 01-02-2000 :: EpiCept Corporation :: 777 Old Saw Mill River Road :: Tarrytown NY 10591Histamine :: Ceplene :: Adjunct to cytokine therapy in the treatment of acute myeloid leukemia. :: 15-12-1999 :: EpiCept Corporation :: 777 Old Saw Mill River Road :: Tarrytown NY 10591Histrelin :: Treatment of acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria. :: 03-05-1991 :: Anderson, Karl E., M.D. :: University of Texas Medical Branch at Galveston :: Route J-09, 700 The Strand :: Galveston TX 77550 HIV neutralizing antibodies :: Immupath :: Treatment of acquired immunodeficiency syndrome. :: 24-03-1992 :: Hemacare Corporation :: 4954 Van Nuys Boulevard :: Sherman Oaks CA 91403HLA-B7/Beta2M DNA Lipid (DMRIE/DOPE) Complex :: Allovectin-7 :: Treatment of invasive and metastatic melanoma (Stages II, III, and IV). :: 30-09-1999 :: Vical Incorporated :: 9373 Towne Centre Dr., Suite 100 :: San Diego CA 92121homoharringtonine :: Treatment for chronic myelogenous leukemia :: 08-02-2002 :: American BioScience, Inc. :: 2730 Wilshire Blvd. #110 :: Santa Monica CA 90403HPA-23 :: Treatment of acquired immunodeficiency syndrome. :: 17-07-1985 :: Rhone-Poulenc Rorer Pharm. :: 500 Arcola Road :: Collegeville PA 19426HPV-16 cancer therapeutic trojan peptide vaccine :: Treatment of HPV-16 expressing head and neck squamous cell carcinoma. :: 12-01-2009 :: Gliknik, Inc. :: 801 W. Baltimore Street :: Baltimore MD 21201Hsp E7 :: Treatment of recurrent respiratory papillomatosis (RRP) :: 19-03-2001 :: StressGen Biotechnologies, Inc. is now Nventa :: Nventa Biopharmaceuticals Corporation :: 6055 Lusk Boulevard :: San Diego CA 19426-2655Hu1D10, humanized monoclonal antibody :: Remitogen :: For use in the treatment of 1D10+ B cell non-Hodgkin's lymphoma :: 28-11-2001 :: PDL BioPharma, Inc. :: 34801 Campus Drive :: Fremont CA 94555Human acid precursor alpha-glucosidase, recombinant :: Treatment of glycogen storage disease type II. :: 10-09-1996 :: Pharming/Genzyme LLC :: c/o Genzyme Corporation :: 1 Mountain Rd. :: Framingham MA 01701-9322Human alpha 2,6 sialyltransferase adenoviral gene therapy :: Treatment of patients with invasive (malignant) brain and central nervous system tumors lacking alpha 2,6 sialyltransferase. :: 04-04-2005 :: Falk Center for Molecular Therapeutics :: 1801 Maple Avenue :: Suite 4300 :: Evanston IL 60201 Human anti-CD30 monoclonal antibody :: Treatment of Hodgkin's disease :: 27-09-2004 :: Medarex, Inc. :: 519 Route 173 West :: Bloomsbury NJ 08804human anti-CD4 monoclonal antibody :: HuMax-CD4 :: Treatment of mycosis fungoides :: 13-08-2004 :: Genmab A/S :: Tolbodgade 33 :: DK-1253 Copenhagen K :: DENMARKhuman anti-cellular adhesion molecule-1 monoclonal antibody :: Treatment of multiple myeloma :: 29-07-2008 :: BioInvent International AB :: Solvegatan 41 :: SWEDENHuman anti-integrin receptor av monoclonal antibody :: Treatment of patients with angiosarcoma :: 05-05-2005 :: Centocor, Inc. :: 200 Great Valley Parkway :: Malvern PA 19355-1307 human anti-integrin receptor avb3/avb5 monoclonal antibody :: Treatment of patients with high-risk stage II, stage III, and stage IV malignant melanoma :: 01-12-2004 :: Centocor, Inc. :: 200 Great Valley Parkway :: Malvern PA 19355-1307 human anti-transforming growth factor beta 1 monoclonal antibody :: Treatment of systemic sclerosis :: 11-01-2002 :: Genzyme Corporation :: One Kendall Square :: Cambridge MA 02139human anti-transforming growth factor-B1,2,3 :: Treatment of idiopathic pulmonary fibrosis :: 09-07-2004 :: Genzyme Corporation :: 500 Kendall Street :: Cambridge MA 02142Human autologous bone-forming cell derived from bone marrow stem cells :: Treatment of osteonecrosis :: 24-03-2008 :: Bone Therapeutics S.A. :: 8, rue Adrienne Bolland :: BELGIUMhuman coagulation factor XI :: Hemoleven :: Treatment of severe congential Factor XI deficiency. :: 08-11-2007 :: Laboratoire francais du Fractionnement et des Biot :: 3 Avenue des Tropiques :: 91985 Courtaboeuf Cedex :: FRANCEHuman cytomegalovirus immunoglobulin :: Prevention of congenital cytomegalovirus (CMV) infection following primary CMV infection in pregnant women :: 20-12-2006 :: Biotest Diagnostics Corporation :: 66 Ford Road :: Denville NJ 07834Human factor X :: Treatment of hereditary factor X deficiency :: 08-11-2007 :: Bio Products Laboratory :: Dagger Lane :: Hertfordshire, WD6 3BX :: UNITED KINGDOMhuman gammaglobulin :: Treatment of gastrointestinal disturbances (to include constipation, diarrhea, and abdominal pain) associated with regression-onset autism in pediatric patients. :: 16-09-2002 :: Protein Therapeutics, Inc. :: 70 Calle Encanto :: Tucson AZ 85716human gammaglobulin :: Treatment of idiopathic inflammatory myopathies :: 14-11-2003 :: Protein Therapeutics, Inc. :: 70 Calle Encanto :: Tucson AZ 85716human gammaglobulin :: Treatment for juvenile rheumatoid arthritis :: 25-05-2001 :: Protein Therapeutics, Inc. :: 70 Calle Encanto :: Tuscon AZ 85716Human IgM monoclonal antibody (C-58) To CMV :: Centovir :: Prophylaxis of cytomegalovirus infections in bone marrow transplant patients. :: 07-08-1989 :: Centocor, Inc. :: 244 Great Valley Parkway :: Malvern PA 19355Human IgM monoclonal antibody (C-58) To CMV :: Centovir :: Treatment of cytomegalovirus infections in allogenic bone marrow transplant patients. :: 07-08-1989 :: Centocor, Inc. :: 244 Great Valley Parkway :: Malvern PA 19355Human immune globulin :: Xepol :: Treatment of post-polio syndrome :: 29-03-2006 :: Pharmalink AB :: P. O. Box 625 :: SWEDENHuman immunodeficiency virus immune globulin :: Treatment of AIDS. :: 21-11-1989 :: NABI :: 5800 Park of Commerce Blvd., NW :: Boca Raton FL 33487Human immunodeficiency virus immune globulin :: Treatment of HIV-infected pregnant women and infants of HIV-infected mothers. :: 25-03-1992 :: NABI :: 5800 Park of Commerce Blvd., N.W. :: Boca Raton FL 33487Human immunodeficiency virus immune globulin :: Hivig :: Treatment of HIV-infected pediatric patients. :: 04-01-1995 :: NABI :: 5800 Park of Commerce Blvd., NW :: Boca Raton FL 33487Human immunoglobin anti-CD30 monoclonal antibody :: Treatment of CD30+ T-cell lymphoma :: 10-01-2006 :: Medarex, Inc. :: 519 Route 173 West :: Bloomsbury NJ 08804Human immunoglobulin (IgG1k)antiCTLA-4 monoclonal antibody :: Treatment of high risk Stage II, Stage III, and Stage IV melanoma :: 03-06-2004 :: Bristol-Myers Squibb Pharmaceutical Research Insti :: 5 Research Parkway :: Signature 91 Bldg/3SIG-3012 :: Wallingford CT 06492 human leukocyte-derived cytokine mixture :: Neoadjuvant therapy in patients with squamous cell carcinoma of the head and neck :: 07-07-2005 :: IRX Therapeutics, Inc. :: 140 West 57th Street :: New York City NY 10019Human monoclonal antibody against platelet-derived growth factor D :: To slow the progression of IgA nephropathy and delay kidney failure in patients affected by the disease. :: 02-11-2004 :: CuraGen Corporation :: 322 East Main Street :: Branford CT 06405Human monoclonal antibody directed against serotype 011 Pseudomonas aeruginosa :: Aerumab 11 :: Treatment of hospital acquired pneumonia caused by serotype 011 positive Pseudomonas aeruginosa :: 18-09-2006 :: Kenta Biotech Limited :: Rehhagstrsase :: SWITZERLANDHuman monoclonal antibody of the Ig1/k-isotype against human interleukin-1 beta :: Treatment of cryopyrin-associated periodic syndromes :: 18-12-2007 :: Novartis Pharmaceuticals Corporation :: One Health Plaza :: East Hanover NJ 07936-1080 Human monoclonal antibody targeting CC-chemokine ligand 2 :: Treatment of pancreatic cancer :: 24-10-2006 :: Centocor, Inc. :: 200 Great Valley PArkway :: Malvern PA 19355-1307 Human plasma coagulation Factor VIII and human plasma von Willebrand Factor :: Wilate :: Treatment of von Willebrand disease except for surgical and/or invasive procedures in patients with von Willebrand disease in whom desmopressin is either ineffective or contraindicated :: 18-04-2007 :: Octapharma USA, Inc. :: 121 River Street :: 12th Floor :: Hoboken NJ 07030 Human prothrombin complex concentrate :: Octaplex :: Reversal of anticoagulation therapy in patients needing treatment of serious or life threatening bleeding and/or needing urgent surgery or invasive procedures :: 01-02-2008 :: Octapharma USA, Inc. :: 121 River Street :: 12th Floor :: Hoboken NJ 07030 human recombinant fusion protein :: Treatment of hypophosphatasia :: 12-09-2008 :: Enobia Pharma, Inc. :: 2901 Rachel Street East :: Montreal, QC H1W 4A4 :: CANADAHuman telomerase reverse transcriptase peptide vaccine :: Treatment of pancreatic cancer :: 20-07-2006 :: GemVax A/S :: Drammensveien 100 :: 0273 Oslo :: NORWAYHuman T-lymphotropic virus type III Gp160 antigens :: Vaxsyn HIV-1 :: Treatment of AIDS. :: 20-11-1989 :: MicroGeneSys, Inc. :: 1000 Research Parkway :: Meriden CT 06450Human umbilical tissue-derived cells :: Treatment of retinitis pigmentosa :: 13-03-2006 :: Centocor, Inc :: 200 Great Valley Parkway :: Malvern PA 19355-1307 Humanized anti-CD2 monoclonal antibody :: Treatment of graft-versus-host disease. :: 13-11-1998 :: MedImmune, Inc. :: 35 West Watkins Mill Rd. :: Gaithersburg MD 20878Humanized anti-CD3 monoclonal antibody :: Treatment of recent-onset Type I diabetes :: 29-09-2006 :: MacroGenics, Inc. :: 1500 East Gude Drive :: Rockville MD 20850humanized anti-human CD16 monoclonal antibody :: Treatment of adult idiopathic thrombocytopenic purpura :: 21-03-2005 :: Genzyme Corporation :: 500 Kendall Street :: Cambridge MA 02142Humanized anti-human CD2 MAb :: MEDI-507 :: For the induction of donor-specific immunologic unresponsiveness resulting in prophylaxis of organ rejection without the need for chronic immunosuppressive therapy, in patients receiving allogeneic renal transplants. :: 17-09-1998 :: Biotransplant, Inc. :: Building 75, 3rd. Ave. :: Charlestown Navy Yard :: Charlestown MA 02129 Humanized anti-tac :: Zenapax :: Prevention of acute graft-vs-host disease following bone marrow transplantation. :: 05-03-1993 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110-1199 humanized IgG2 antibody :: Treatment of vaso-occlusive crisis in patients with sickle cell disease. :: 22-07-2008 :: Selexys Pharmaceuticals Corp. :: 800 Research Parkway :: Suite 338 :: Oklahoma OK 73104 Humanized MAb (IDEC-131) to CD40L :: Treatment of systemic lupus erythematosus. :: 09-02-1999 :: Biogen IdecInc. :: 3030 Callan Rd. :: San Diego CA 92121humanized monoclonal antibody against Shiga-like toxin II :: To prevent the development of or to decrease the incidence and severity of hemolytic uremic syndrome and associated sequelae of Shiga-like toxin-producing E. coli. :: 12-09-2001 :: Teijin America, Inc. :: 600 Alexander Park :: Suite 304 :: Princeton NJ 08540 Humanized monoclonal antibody to the high affinity folate alpha receptor :: Treatment of ovarian cancer :: 16-06-2006 :: Morphotek, Inc. :: 210 Welsh Pool Road :: Exton PA 19341humanized monocloncal antibody against human integrin alphaVbeta6 :: Treatment of fibrosis-associated chronic allograft nephropathy in kidney transplant patients. :: 18-06-2008 :: Stromedix, Inc. :: One Canal Park :: Cambridge MA 02141hyaluronic acid :: Treatment of emphysema in patients due to alpha-1 antitrypsin deficiency :: 19-03-2002 :: CoTherix :: 5000 Shoreline Court :: Suite 101 :: South San Francisco CA 94080 Hydralazine :: Treatment of severe intrapartum hypertension (diastolic blood pressure greater than or equal to 110 or systolic blood pressure greater than or equal to 160) associated with severe preeclampsia/eclampsia of pregnancy :: 09-04-2004 :: Barbeau Pharma, Inc. :: 790 W. Frontage Road :: Suite 125 :: Northfield IL 60093 hydrocortisone modified release tabs :: DuoCort :: Treatment of adrenal insufficiency :: 18-06-2008 :: DuoCort AB :: Kullagatan 8-10, S-252 20 Helsingborg :: SWEDENHydroxocobalamin :: Treatment of acute cyanide poisoning :: 22-09-2000 :: Jazz Pharmaceuticals :: 3180 Porter Drive :: Palo Alto CA 94304Hydroxycobalamin/sodium thiosulfate :: Treatment of severe acute cyanide poisoning. :: 04-10-1985 :: Hall, Alan H., M.D. :: Mile 5.0 Pass Creek Road :: PO Box 24 :: Elk Mountain WY 82324 hydroxyurea :: Treatment of pediatric patients with sickle cell anemia. :: 15-04-2005 :: UPM Pharmaceuticals, Inc. :: 6200 Seaforth Street :: Baltimore MD 21224Hypericin :: Treatment of glioblastoma multiforme. :: 03-08-2000 :: Nexell Therapeutics :: 2751 Centerville Rd., Suite 210 :: Wilmington DE 19808Hypericin :: Treatment of cutaneous T-cell lymphoma. :: 07-02-2000 :: Nexell Therapeutics, Inc. :: 2751 Centerville Rd., Suite 210 :: Wilmington DE 19808I(131)-TM-601 (chlorotoxin) :: Treatment of malignant glioma :: 14-02-2002 :: TransMolecular, Inc. :: 840 Memorial Drive :: Second Floor :: Cambridge MA 02139 Iboctadekin :: Treatment of renal cell carcinoma :: 03-06-2005 :: GlaxoSmithKline :: PO Box 13398 :: Five Moore Drive :: Research Triangle Park NC 27709-3398Ibuprofen i.v. solution :: Salprofen :: Prevention of patent ductus arteriosus. :: 29-10-1996 :: Farmacon-IL, LLC :: 1720 Post Road East :: Suite 213 :: Westport CT 06880-5643icatibant :: Treatment of burn patients hospitalized with burn-induced edema :: 05-05-2004 :: Jerini AG :: Invalidenstr, 130 :: 10115 Berlin :: GERMANYicatibant :: Treatment of angioedema :: 25-11-2003 :: Jerini AG :: A subsidiary of Shire PLC :: Invalidenstr. 130 :: GERMANYIdarubicin :: Idamycin :: Treatment of chronic myelogenous leukemia. :: 02-12-1992 :: Pharmacia & Upjohn :: 7000 Portage Road :: Unit 0633-298-113 :: Kalamazoo MI 49001-0199Idarubicin :: Idamycin :: Treatment of myelodysplastic syndromes. :: 01-12-1992 :: Pharmacia & Upjohn :: 7000 Portage Road :: Unit 0633-298-113 :: Kalamazoo MI 49001-0199Idarubicin HCl for injection :: Idamycin :: Treatment of acute lymphoblastic leukemia in pediatric patients. :: 12-02-1991 :: Pharmacia & Upjohn :: 7000 Portage Road :: Unit 0633-298-113 :: Kalamazoo MI 49001-0199idebenone :: Treatment of Leber's hereditary optic neuropathy. :: 31-10-2006 :: Santhera Pharmaceuticals Limited :: Hammerstrasse 47 :: SWITZERLANDidebenone :: Treatment of Duchenne muscular dystrophy :: 16-02-2007 :: Santhera Pharaceuticals Limited :: Hammerstrasse 47 :: SWITZERLANDIdebenone :: Treatment of Friedreich's ataxia :: 25-03-2004 :: Santhera Pharmaceuticals LLC :: Hammerstrasse 25 :: CH-4410 Liestal :: SWITZERLANDIdoxuridine :: Treatment of nonparenchymatous sarcomas. :: 08-04-1996 :: NeoPharm, Inc. :: 225 East Deerpath, Suite 250 :: Lake Forest IL 60045IDUA-HIRMAb fusion protein :: AGT-181 :: Treatment of mucopolysaccharidosis Type 1 (MPS) :: 10-01-2008 :: ArmaGen Technologies, Inc. :: 914 Colorado Ave. :: Santa Monica CA 90401Ifosfamide :: Ifex :: Treatment of bone sarcomas :: 07-08-1985 :: Bristol-Myers Squibb Company :: P.O. Box 4000 :: Mail Stop D12-02 :: Princeton NJ 08543-4000Ifosfamide :: Ifex :: Treatment of soft tissue sarcomas. :: 07-08-1985 :: Bristol-Myers Squibb Pharmaceutical Research Institute :: P.O. Box 4000 :: Princeton NJ 08543IL13-PE38QQR :: Treatment of malignant glioma :: 02-11-2001 :: NeoPharm, Inc. :: 150 Field Drive :: Suite 195 :: Lake Forest IL 60045 IL-4 Pseudomonas Toxin Fusion Protein (IL-4(38-37)-PE38KDEL) :: Treatment of astrocytic glioma. :: 06-04-2000 :: Protox Therapeutics, Inc. :: 1210-885 West Georgia :: Vancouver, British Columbia :: San Diego :: CANADAIloprost solution for infusion :: Treatment of Raynaud's phenomenon secondary to systemic sclerosis. :: 21-09-1989 :: Berlex Laboratories, Inc. :: 300 Fairfield Road :: Wayne NJ 07470Iloprost solution for infusion :: Treatment of heparin-associated thrombocytopenia. :: 14-05-1990 :: Berlex Laboratories, Inc. :: 300 Fairfield Road :: Wayne NJ 07470Imciromab pentetate :: Myoscint :: Detecting early necrosis as an indication of rejection of orthotopic cardiac transplants. :: 25-01-1989 :: Centocor, Inc. :: 244 Great Valley Parkway :: Malvern PA 19355imexon :: Amplimexon :: Treatment of ovarian cancer. :: 12-08-2005 :: AmpliMed Corporation :: 4380 N. Campbell Ave. :: Tucson AZ 85718Imexon :: Treatment of multiple myeloma. :: 08-11-1996 :: AmpliMed Corporation :: 2321 Camino La Zorrela :: Tucson AZ 85718Imexon :: Treatment of pancreatic adenocarcinoma :: 01-11-2003 :: AmpliMed Corporation :: 2321 Camino La Zorrela :: Tucson AZ 85718Imexon :: Treatment of metastatic malignant melanoma :: 03-08-2001 :: AmpliMed Corporation :: 2321 Camino La Zorrela :: Tucson AZ 85718Immortalized human liver cells found in the extracorporeal liver assist device :: ELAD :: Treatment of fulminant hepatic failure (acute liver failure) :: 16-07-2004 :: Vital Therapies, Inc. :: 15222 Avenue of Science :: Suite C :: San Diego CA 92128 Immune Globulin (Human) containing high titers of West Nile virus antibodies :: Omr-IgG-am ™ 5% (WNV) :: Treatment of the West Nile virus infection :: 17-03-2004 :: OMRIX Biopharmaceuticals, Ltd. :: Plasma Fractionation Institute :: Ramat Gan 52621 :: ISRAELImmune Globulin Intravenous (human) :: Carimune NF :: Treatment for Guillain Barre Syndrome :: 04-05-2004 :: ZLB Bioplasma AG :: Wankdorfstrasse 10 :: CH-3000 Bern 22 :: SWITZERLANDImmune globulin intravenous (human) :: Gammagard Liquid :: Treatment of multifocal motor neuropathy :: 20-07-2006 :: Baxter Healthcare Corporation, :: Baxter Bioscience :: Westlake Village CA 91362Immune globulin intravenous (human) :: Immune Globulin Intravenous (human) Immuno, Iveegam :: Treatment of patients with acute myocarditis. :: 22-11-1993 :: Immuno Clinical Research Corp. :: 750 Lexington Avenue :: New York NY 10022Immune globulin intravenous (human) :: Iveegam, Immuno :: Treatment of polymyositis/dermatomyositis. :: 13-10-1992 :: Immuno Clinical Research Corp. :: 155 East 56th Street :: New York NY 10022Immune globulin intravenous (human) :: Iveegam, Immuno :: Treatment of juvenile rheumatoid arthritis. :: 16-12-1992 :: Immuno Clinical Research Corp. :: 750 Lexington Avenue, 19th Floor :: New York NY 10022Immune Globulin Subcutaneous (Human) :: Vivaglobin P (proposed) :: Treatment of patients with primary immune deficiency (PID) that are intolerant to immune globulin intravenous (IGIV) due to severe adverse events or poor venous access :: 22-09-2004 :: CSL Behring :: 1020 First Avenue :: P.O. Box 61501 :: King of Prussia PA 19406-0901Implitapide :: Treatment of homozygous familial hypercholesterolemia :: 13-08-2004 :: Medical Research Laboratories International :: 2 Tesseneer Drive :: Highland Heights KY 41076Implitapide :: Treatment of patients with Fredrickson type I or V hyperlipoproteinemia :: 19-08-2004 :: Medical Research Laboratories International :: 2 Tesseneer Drive :: Highland Heights KY 41076Imported fire ant venom, allergenic extract :: For skin testing of victims of fire ant stings to confirm fire ant sensitivity and if positive, for use as immunotherapy for the prevention of IgE-mediated anaphylactic reactions. :: 12-05-1992 :: ALK Laboratories, Inc. :: Research Center :: 27 Village Lane :: Wallingford CT 06492 Inalimarev and falimarev :: Treatment of adenocarcinoma of the pancreas :: 10-01-2006 :: Therion Biologics Corporation :: 76 Rogers Street :: Cambridge MA 02142Indium In 111 murine monoclonal antibody FAB to myosin :: Myoscint :: To aid in the diagnosis of myocarditis. :: 07-08-1989 :: Centocor, Inc. :: 244 Great Valley Parkway :: Malvern PA 19355Indium In-111 altumomab pentetate :: Hybri-ceaker :: Detection of suspected and previously unidentified tumor foci of recurrent colorectal carcinoma. :: 06-02-1990 :: Hybritech, Inc. :: 11095 Torreyanna Road :: San Diego CA 92196Indium-111 pentetreotide :: NeuroendoMedix :: Treatment of neuroendocrine tumors :: 16-06-2006 :: RadioIsotope Therapy of America (RITA) Foundation :: 9701 Richmond Avenue :: Houston TX 77042infliximab :: Remicade :: Treatment of juvenile rheumatoid arthritis :: 23-10-2002 :: Centocor, Inc. :: 200 Great Valley Parkway :: Malvern PA 19355-1307infliximab :: Remicade :: Treatment of giant cell arteritis :: 06-05-2003 :: Centocor, Inc. :: 200 Great Valley Parkway :: Malvern PA 19355-1307 Infliximab :: REMICADE :: Treatment of pediatric (0 to 16 years of age) ulcerative colitis :: 12-11-2003 :: Centocor, Inc. :: 200 Great Valley Parkway :: Malvern PA 19355-1307 Infliximab :: Remicade :: Treatment of chronic sarcoidosis :: 21-05-2003 :: Centocor, Inc. :: 200 Great Valley Parkway :: Malvern PA 19355-1307 INGN 201 :: ADVEXIN :: Treatment of head and neck cancer :: 27-01-2003 :: Introgen Therapeutics, Inc. :: 2250 Holcombe Blvd :: Houston TX 77030 INH-A00021 :: Veronate :: Reduction (prevention) of nosocomial bacteremia caused by staphylococci in very low birth weight infants. :: 13-06-2001 :: Inhibitex, Inc. :: 8995 Westside Parkway :: Suite 150 :: Alpharetta GA 30004 inolimomab :: Leukotac :: Treatment of graft versus host disease :: 23-10-2002 :: EUSA Pharma :: 650 College Road East :: Suite 3100 :: Princeton NJ 08540 Inosine pranobex :: Isoprinosine :: Treatment of subacute sclerosing panencephalitis. :: 20-09-1988 :: Newport Pharmaceuticals :: 897 West Sixteenth Street :: Newport Beach CA 92663Interferon alfa-2a (recombinant) :: Roferon-A :: Treatment of renal cell carcinoma. :: 18-04-1988 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110-1199 Interferon alfa-2a (recombinant) :: Roferon-A :: For the treatment of metastatic malignant melanoma in combination with Teceleukin. :: 11-05-1990 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110Interferon alfa-2a (recombinant) :: Roferon-A :: For the concomitant administration with Teceleukin for the treatment of metastatic renal cell carcinoma. :: 02-05-1990 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07119Interferon alfa-2a (recombinant) :: Roferon-A :: For the concomitant administration with fluorouracil for the treatment of advanced colorectal cancer. :: 14-05-1990 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110-1199 Interferon alfa-2a (recombinant) :: Roferon-A :: For use in combination with fluorouracil for the treatment of esophageal carcinoma. :: 27-10-1989 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110-1199 Interferon alfa-2b (recombinant) :: Intron A :: Treatment of acute hepatitis B. :: 17-11-1988 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Interferon alfa-2b (recombinant) :: Intron A :: Treatment of primary malignant brain tumors. :: 13-05-1988 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Interferon alfa-2b (recombinant) :: Intron A :: Treatment of carcinoma in situ of the urinary bladder. :: 10-08-1988 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Interferon alfa-2b (recombinant) :: Intron A :: Treatment of invasive carcinoma of the cervix. :: 18-04-1988 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Interferon alfa-2b (recombinant) :: Intron A :: Treatment of ovarian carcinoma. :: 03-08-1987 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Interferon alfa-2b (recombinant) :: Intron A :: Treatment of chronic myelogenous leukemia. :: 22-06-1987 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Interferon alfa-2b (recombinant) :: Intron A :: Treatment of metastatic renal cell carcinoma. :: 22-06-1987 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Interferon alfa-2b (recombinant) :: Intron A :: Treatment of laryngeal (respiratory) papillomatosis. :: 17-08-1988 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Interferon alfa-2b (recombinant) :: Intron A :: Treatment of chronic delta hepatitis. :: 04-05-1990 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Interferon alfa-nl :: Wellferon :: Treatment of human papillomavirus in patients with severe resistant/recurrent respiratory (laryngeal) papillomatosis. :: 16-10-1987 :: Glaxo Wellcome Inc. :: 5 Moore Drive :: Research Triangle Park NC 27709Interferon alfa-nl :: Wellferon :: Treatment of AIDS related Kaposi's sarcoma. :: 25-08-1986 :: Burroughs Wellcome Company :: 3030 Cornwallis Road :: Research Triangle Pk NC 27709Interferon beta (recombinant) :: R-IFN-beta :: For the systemic treatment of metastatic renal cell carcinoma. :: 12-02-1991 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Interferon beta (recombinant) :: r-HuIFN-beta :: For the intralesional and/or systemic treatment of AIDS-related Kaposi's sarcoma. :: 09-05-1991 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Interferon beta (recombinant) :: r-HuIFN-beta :: For the systemic treatment of cutaneous T-cell lymphoma. :: 18-04-1991 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Interferon beta, recombinant human :: Betaseron :: Treatment of acquired immunodeficiency syndrome. :: 15-11-1988 :: Berlex Laboratories, Inc. :: 15049 San Pablo Avenue, P.O. Box 4099 :: Richmond CA 94804Interferon beta-1a :: Rebif :: Treatment of patients with secondary progressive multiple sclerosis. :: 11-03-1996 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370interferon Beta-1a :: Avonex :: Treatment of juvenile rheumatoid arthritis. :: 14-10-1998 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Interferon beta-1a (recombinant human) :: Treatment of acute non-A, non-B hepatitis. :: 24-07-1992 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Interferon beta-1a (recombinant) :: r-HuIFN-beta :: For the systemic treatment of cutaneous malignant melanoma. :: 03-04-1991 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Interferon beta-1a (recombinant) :: Rebif :: Treatment of symptomatic patients with AIDS including all patients with CD4 T-cell counts less than 200 cells per mm3. :: 02-12-1992 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370Interferon gamma :: Treatment of idiopathic pulmonary fibrosis :: 11-10-2007 :: Foundation for Fatal Rare Diseases :: Herrengasse 21 :: Furstentum Liechtenstein :: GERMANYinterferon gamma-1b :: Actimmune :: Treatment of idiopathic pulmonary fibrosis :: 12-09-2002 :: InterMune, Inc. :: 3280 Bayshore Boulevard :: Brisbane CA 94005Interferon gamma-1b :: Actimmune :: Treatment of renal cell carcinoma. :: 04-12-1995 :: Genentech, Inc. :: 1 DNA Way :: South San Francisco CA 94080-4990 Interferon-alfa-1b :: Treatment of multiple myeloma :: 17-04-2001 :: Ernest C.Borden :: Center for Cancer Drud Discovery and Development :: 9500 Euclid Avenue :: Clevland OH 44195 Interleukin-1 alpha, human recombinant :: For hematopoietic potentiation in aplastic anemia. :: 17-06-1991 :: Immunex Corporation :: 51 University Street :: Seattle WA 98101Interleukin-1 alpha, human recombinant :: For the promotion of early engraftment in bone marrow transplantation. :: 17-06-1991 :: Immunex Corporation :: 51 University Street :: Seattle WA 98101Interleukin-1 receptor antagonist, human recombinant :: Antril :: Treatment of juvenile rheumatoid arthritis. :: 23-09-1991 :: Amgen, Inc. :: One Amgen Center Drive :: Thousand Oaks CA 91320-1799 Interleukin-1 receptor antagonist, human recombinant :: Antril :: Prevention and treatment of graft versus host disease in transplant recipients. :: 16-10-1992 :: Amgen, Inc. :: One Amgen Center Drive :: Thousand Oaks CA 91320-1799 Interleukin-1 Trap :: Treatment of Still's disease including juvenile rheumatoid arthritis and adult-onset Still's disease :: 04-04-2005 :: Regeneron Pharmaceuticals, Inc. :: 777 Old Saw Mill River Road :: Tarrytown NY 10591Interleukin-2 :: Teceleukin :: In combination with interferon alfa-2a for the treatment of metastatic malignant melanoma. :: 11-05-1990 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110Interleukin-2 :: Teleleukin :: Treatment of metastatic malignant melanoma. :: 06-02-1990 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110Interleukin-2 :: Teceleukin :: Treatment of metastatic renal cell carcinoma. :: 05-02-1990 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110Interleukin-2 :: Teceleukin :: In combination with interferon alfa-2a for the treatment of metastatic renal cell carcinoma. :: 03-05-1990 :: Hoffmann-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110Interleukin-3 human (recombinant) :: Promotion of erythropoiesis in Diamond-Blackfan anemia (congenital pure red cell aplasia). :: 20-05-1991 :: Immunex Corporation :: 51 University Street :: Seattle WA 98101Interleukin-3, human, recombinant :: For sequential administration with sargramostim to accelerate neutrophil and platelet recovery in patients undergoing autologous bone marrow transplantation for the treatment of Hodgkin's disease or non-Hodgkin's lymphoma. :: 30-09-1993 :: Sandoz Pharmaceuticals Corp. :: 59 Route 10 :: East Hanover NJ 07936Intraoral fluoride releasing system :: IFRS :: Prevention of dental caries due to radiation-induced xerostomia in patients with head and neck cancer :: 31-07-2001 :: Digestive Care, Inc. :: 1120 Win Drive :: Bethlehem PA 18017Intravenous immune globulin :: VitiGam :: Treatment of Stage IIB to IV malignant melanoma :: 26-07-2007 :: GammaCan Ltd. :: 39 Jerusalem Street :: ISRAELIntravenous immune globulin (human) 10% :: Octagam :: Treatment of stiff-person syndrome :: 31-07-2008 :: Octapharma USA, Inc. :: 121 River Street :: Hoboken NJ 07030iobenguane I 131 :: Treatment of neuroendocrine tumors :: 05-07-2007 :: DraxImage :: Div. of Draxis Specialty Pharmaceuticals, Inc. :: Kirkland, Quebec H9H 4J4 :: CANADAIobenguane I 131 :: Azedra Ultratrace :: Treatment of neuroendocrine tumors :: 18-01-2006 :: Molecular Insight Pharmaceuticals :: 160 Second street :: Cambridge MA 02142Iobenguane Sulfate I-123 :: OmaClear :: For scintigraphic detection, localization and staging of neuroblastoma. :: 17-10-2005 :: Brogan Pharmaceuticals, LLC :: 312 Lacebark Street :: Schererville IN 46375iobenguane sulfate I-123 :: OmaClear :: For the detection, localization, and staging of pheochromocytomas. :: 21-10-2005 :: Brogan Pharmaceuticals, Inc. :: 9800 Connecticut Drive :: c/o Purdue Technology Center :: Crown Point IN 46307 Iodine 131 6B-iodomethyl-19-norcholesterol :: For use in adrenal cortical imaging. :: 01-08-1984 :: David E. Kuhl, M.D. :: University of Michigan Medical Center/1500 E. Med. :: B1G412 /0028 University Hospital :: Ann Arbor MI 48109-0028Iodine I 123 murine monoclonal antibody to alpha-fetoprotein :: Detection of alpha-fetoprotein producing germ cell tumors. :: 30-09-1988 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Iodine I 123 murine monoclonal antibody to alpha-fetoprotein :: Detection of hepatocellular carcinoma and hepatoblastoma. :: 30-09-1988 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Iodine I 123 murine monoclonal antibody to hCG :: Detection of hCG producing tumors such as germ cell and trophoblastic cell tumors. :: 07-11-1988 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Iodine I 131 bis(indium-diethylenetriaminepentaacetic acid)tyrosyllysine/hMN-14 x m734 F(ab')2 bispecific monoclonal antibody :: Pentacea :: Treatment of small-cell lung cancer. :: 22-02-2000 :: IBC Pharmaceuticals, L.L.C. :: 300 American Rd. :: Morris Plains NJ 07950Iodine I 131 Lym-1 Monoclonal Antibody :: Treatment of B-cell lymphoma. :: 02-11-1987 :: Lederle Laboratories Division :: American Cyanamide Company :: 401 N. Middletown Road :: Pearl River NY 10965 Iodine I 131 murine monoclonal antibody IgG2a to B cell :: Immurait, Ll-2-I-131 :: Treatment of B-cell leukemia and B-cell lymphoma. :: 18-09-1989 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Iodine I 131 murine monoclonal antibody to alpha-fetoprotein :: Treatment of alpha-fetoprotein producing germ cell tumors. :: 30-09-1988 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Iodine I 131 murine monoclonal antibody to alpha-fetoprotein :: Treatment of hepatocellular carcinoma and hepatoblastoma. :: 30-09-1988 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Iodine I 131 murine monoclonal antibody to hCG :: Treatment of hCG producing tumors such as germ cell and trophoblastic cell tumors. :: 07-11-1988 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Iodine I-131 radiolabeled chimeric MAb tumor necrosis treatment (TNT-1B) :: 131IchTNT-1 :: Treatment of glioblastoma multiforme and anaplastic astrocytoma. :: 12-02-1999 :: Peregrine Pharmaceuticals, Inc. :: 14282 Franklin Ave. :: Tustin CA 92780-7017 irofulven :: Treatment of renal cell carcinoma. :: 27-07-1999 :: Eisai Medical Research, Inc. :: 55 Challengaer Road :: Ridgefield Park NJ 07660irofulven :: Treatment of ovarian cancer. :: 06-07-1999 :: Eisai Medical Research, Inc. :: 55 Challenger Road :: Rodgefield Park NJ 07660Isobutyramide :: Treatment of sickle cell disease and beta thalassemia. :: 25-05-1994 :: Alpha Therapeutic Corporation :: 5555 Valley Boulevard :: Los Angeles CA 90032Isobutyramide :: Isobutyramide oral solution :: Treatment of beta-hemoglobinopathies and beta-thalassemia syndromes. :: 18-12-1992 :: Perrine, Susan P., M.D. :: Boston University :: Cancer Research Center :: Boston MA 02118 isofagomine tartrate :: Treatment of Gaucher disease :: 10-01-2006 :: Amicus Therapeutics, Inc. :: 6 Cedar Brook Drive :: Cranbury NJ 08512Itraconazole suspension :: Topical treatment of fungal otitis externa (otomycosis) :: 30-10-2008 :: Fairfield Clinical Trials, LLC :: 200 Steep Hill Road :: Weston CT 06883IV Sotalol :: So-Aqueous :: For ventricular tachycardia, ventricular fibrillation, or the maintenance of sinus rhythm in patients converted from atrial fibrillation or atrial flutter when oral administration is not possible. :: 25-07-2008 :: Academic Pharmaceuticals :: 21 N. Skokie Hwy :: Lake Bluff IL 60044JAK tyrosine kinase inhibitor :: Treatment of myelofibrosis :: 05-09-2008 :: Incyte Corporation :: Experimental Station :: Bldg E400/6430 :: Wilmington DE 19880 Japanese encephalitis vaccine (live, attenuated) :: Prevention of Japanese encephalitis. :: 19-05-1999 :: Glovax Co., Ltd. :: Room 307, Koryo Academytel, 437-3 :: Ahyun-Dong, Mapo-Gu, Seoul 121-010 :: Ketoconazole :: Nizoral :: For use with cyclosporine A to diminish the nephrotoxicity induced by cyclosporine in organ transplantation. :: 27-03-1991 :: Pharmedic Company :: 28101 Ballard Road :: Lake Forest IL 60045kit for the preparation of technetium Tc99m sulfur colloid :: For localization of sentinel lymph nodes in patients with melanoma. :: 17-03-2009 :: Pharmalucence, Inc. :: 10 DeAngelo Drive :: Bedford MA 01730L-2-oxothiazolidine-4-carboxylic acid :: Procysteine :: Treatment of adult respiratory distress syndrome. :: 14-06-1994 :: Transcend Therapeutics, Inc. :: 640 Memorial Drive, 3rd Floor West :: Cambridge MA 02139L-2-oxothiazolidine-4-carboxylic acid :: Procysteine :: Treatment of amyotrophic lateral sclerosis. :: 30-07-1996 :: Transcend Therapeutics, Inc. :: 640 Memorial Drive, 3rd Floor West :: Cambridge MA 02139L-5-hydroxytryptophan :: Treatment of tetrahydrobiopterin deficiency. :: 20-01-1999 :: Watson Laboratories, Inc. :: 311 Bonnie Circle :: P.O. Box 1900 :: Corona CA 91718-1900Lactic acid :: Aphthaid :: Treatment of severe aphthous stomatitis in severely, terminally immunocompromised patients. :: 29-06-1999 :: Frontier Pharmaceutical, Inc. :: SUNY Farmingdale :: Conklin Hall :: Farmingdale NY 11735 lactic acid bacteria (Lactobacilli, Bifidobacteria, and Steptococci) :: Treatment of active chronic pouchitis :: 15-01-2002 :: VSL Pharmaceuticals, Inc. :: 800 S. Frederick Avenue :: Gaithersburg MD 20877lactic acid bacteria (Lactobacilli, Bifidobacteria, and Streptococcus species) :: Prevention of disease relapse in patients with chronic pouchitis :: 15-01-2002 :: VSL Pharmaceuticals, Inc. :: 800 S. Frederick Ave. :: Gaithersburg MD 20877Lactobin :: Lactobin :: Treatment of AIDS-associated diarrhea unresponsive to initial antidiarrheal therapy. :: 12-09-1990 :: Roxane Laboratories, Inc. :: P.O. Box 16532 :: Columbus OH 43216-6532 L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal :: Treatment of Duchenne and Becker muscular dystrophy :: 18-01-2006 :: CepTor Corporation :: 200 International Circle :: Hunt Valley MD 21030laromustine :: Onrigin :: Treatment of acute myelogenous leukemia :: 21-10-2004 :: Vion Pharmaceuticals, Inc. :: Four Science Park :: New Haven CT 06511Latrodectus immune F(ab)2 :: Aracmyn :: Treatment of black widow spider envenomations :: 18-06-2001 :: Rare Disease Therapeutics, Inc. :: 2550 Meridian Blvd. :: Franklin TN 37067L-baclofen :: Treatment of trigeminal neuralgia. :: 13-07-1990 :: Fromm, Gerhard M.D. :: University Of Pittsburgh School of Medicine :: Pittsburgh PA 15261L-Baclofen :: Neuralgon :: Treatment of intractable spasticity in children with cerebral palsy. :: 30-01-1992 :: Osmotica Kft. L-baclofen :: Neuralgon :: Treatment of intractable spasticity associated with spinal cord injury or multiple sclerosis. :: 17-12-1991 :: Osmotica Kft. L-Baclofen :: Treatment of trigeminal neuralgia. :: 06-01-1998 :: Osmotica Kft. L-cycloserine :: Treatment of Gaucher's disease. :: 01-08-1989 :: Lev, Meir M.D. :: The City College, City University Of NY Medical Sc :: Convent Avenue at 138 Street :: New York NY 10031 L-cysteine :: For the prevention and lessening of photosensitivity in erythropoietic protoporphyria. :: 16-05-1994 :: Brigham and Women's Hospital :: Channing Laboratory :: Dept. of Medicine :: Boston MA 02115 Leflunomide :: Prevention of acute and chronic rejection in patients who have received solid organ transplants. :: 18-10-1996 :: Williams, MD, James W. :: Rush-Presbyterian-St. Luke's Medical Ctr., Dept. o :: 1653 West Congress Parkway :: Chicago IL 60612-3833lenalidomide :: Revlimid(r) :: Treatment of mantle cell lymphoma :: 27-04-2009 :: Celgene Corporation :: 86 Morris Avenue :: Summit NJ 07901lenalidomide :: Revlimid :: Treatment of chronic lymphocytic leukemia. :: 17-01-2007 :: Celgene Corporation :: 86 Morris Avenue :: Summit NJ 07901Lentiviral vector encoded with a human beta-globin gene plasmid :: Thalagen :: Treatment of beta-thalassemia major and beta-thalassemia intermedia :: 11-01-2006 :: Errant Gene Therapeutics, LLC :: 218 North Jefferson Street :: Suite 300 :: Chicago IL 60661 Lestaurtinib :: Treatment of acute myeloid leukemia :: 24-03-2006 :: Cephalon, Inc. :: 41 Moores Road :: Frazer PA 19355Leucovorin calcium :: Wellcovorin :: For use in combination with 5-fluorouracil for the treatment of metastatic colorectal cancer. :: 23-06-1988 :: Glaxo Wellcome Research and Development :: 5 Moore Drive :: PO Box 13398 :: Research Triangle Park NC 27709 leukocyte interlukin :: Multikine :: Neoadjuvant therapy in patients with squamous cell carcinoma of the head and neck :: 04-05-2007 :: CEL-SCI Corporation :: 8229 Boone Blvd. :: Suite 802 :: Vienna VA 22182 Leupeptin :: For use as an adjunct to microsurgical peripheral nerve repair. :: 18-09-1990 :: Neuromuscular Adjuncts, Inc. :: S.U.N.Y. at Stony Brook :: H.S.C. T18-020 :: Stony Brook NY 11794-8181Levocabastine HCl ophthalmic suspension 0.05% :: Treatment of vernal keratoconjunctivitis. :: 29-02-1988 :: Iolab Pharmaceuticals :: 500 Iolab Drive :: Claremont CA 94608Levocarnitine :: Carnitor :: Treatment of manifestations of carnitine deficiency in patients with end stage renal disease who require dialysis. :: 24-11-1986 :: Sigma-Tau Pharmaceuticals, Inc. :: 9841 Washingtonian Blvd. :: Suite 500 :: Gaithersburg MD 20878 Levocarnitine :: Carnitor :: For the treatment of secondary carnitine deficiency in valproic acid toxicity. :: 15-11-1989 :: Sigma-Tau Pharmaceuticals, Inc. :: 9841 Washingtonian Blvd :: Suite500 :: Gaithersburg MD 20878 Levocarnitine :: Carnitor :: For the prevention of secondary carnitine deficiency in valproic acid toxicity. :: 15-11-1989 :: Sigma-Tau Pharmaceuticals, Inc. :: 9841 Washingtonian Blvd. :: Suite 500 :: Gaithersburg MD 20878 Levocarnitine :: Carnitor :: Treatment of zidovudine-induced mitochondrial myopathy. :: 07-04-1997 :: Sigma-Tau Pharmaceuticals, Inc. :: 9841 Washingtonian Blvd :: Suite 500 :: Gaithersburg MD 20878 Levocarnitine :: Carnitor :: Treatment of pediatric cardiomyopathy. :: 22-11-1993 :: Sigma-Tau Pharmaceuticals, Inc. :: 9841 Washingtonian Blvd :: Suite 500 :: Gaithersburg MD 20878 Levodopa and carbidopa :: Duodopa :: Treatment of late stage Parkinson's disease. :: 18-01-2000 :: Solvay Pharmaceuticals, Inc. :: 901 Sawyer Road :: Marietta GA 30062Levofloxacin :: Treatment of pulmonary infections due to Pseudomonas aeruginosa and other bacteria in patients with cystic fibrosis patients :: 27-02-2008 :: Mpex Pharmaceuticals, Inc. :: 11535 Sorrento Valley Road :: San Diego CA 92121L-glutamine :: Treatment of sickle cell disease :: 01-08-2001 :: Emmaus Medical, Inc. :: 3870 Del Amo Blvd :: Unit 507 :: Torrance CA 90503-7701L-glutamyl-L-tryptophan :: Treatment of AIDS-related Kaposi's sarcoma. :: 20-10-1999 :: Implicit Bioscience Pty Ltd :: P. O. Box 2072. :: Toowong Business Center :: AUSTRALIAliarozole :: The treatment of congenital ichthyosis :: 18-06-2004 :: Barrier Therapeutics, Inc :: 600 College Road East :: Princeton NJ 08540Lintuzumab :: Treatment of myelodysplastic syndrome :: 20-03-2007 :: Seattle Genetics, Inc. :: 21823 30th Drive Southeast :: Bothell WA 98021lintuzumab :: Treatment of acute myeloid leukemia. :: 30-01-2007 :: Seattle Genetics, Inc. :: 21823 30th Drive Southeast :: Bothell WA 98021lintuzumab :: Zamyl :: Treatment of acute myelogenous leukemia :: 09-09-2002 :: Protein Design Labs, Inc. :: 34801 Campus Drive :: Fremont CA 94555Lipid/DNA human cystic fibrosis gene :: Treatment of cystic fibrosis. :: 08-04-1996 :: Genzyme Corporation :: Metrowest Place :: P.O. Box 9322 :: Framingham MA 01701-9322Liposomal amphotericin B :: AmBisome :: Treatment of histoplasmosis. :: 10-12-1996 :: Fujisawa USA, Inc. :: 3 Parkway North Center :: Deerfield IL 60015Liposomal annamycin :: Treatment of acute myeloid leukemia :: 17-06-2005 :: Callisto Pharmaceuticals, Inc. :: 420 Lexington Avenue :: New York NY 10170Liposomal annamycin :: Treatment of acute lymphoblastic leukemia :: 17-06-2005 :: Callisto Pharmaceuticals, Inc. :: 420 Lexington Avenue :: New York NY 10170Liposomal ciprofloxacin :: Management of bronchiectasis :: 27-12-2006 :: Aradigm Corporation :: 3929 Point Eden Way :: Hayward CA 94545Liposomal ciprofloxacin for inhalation :: Management of cystic fibrosis :: 19-04-2006 :: Aradigm Corporation :: 3929 Point Eden Way :: Hayward CA 94545Liposomal cisplatin :: LipOva-Pt :: Treatment of ovarian cancer :: 23-05-2006 :: Transave, Inc. :: 11 Deer Park Drive :: Monmouth Junction NJ 08852-1923 Liposomal cyclosporin A :: Cyclospire :: "For aerosolized administration in the prevention and treatment of lung allograft rejection and pulmonary rejection events associated with bone marrow transplantation." :: 30-04-1998 :: Vernon Knight, M.D. :: Baylor College of Medicine, Dept. of Molecular Phy :: One Baylor Plaza :: Houston TX 77030 liposomal cyclosporine for inhalation :: Prevention of bronchiolitis obliterans. :: 24-06-2008 :: PARI Pharma GmbH :: Moosstrasse 3 :: GERMANYLiposomal doxorubicin hydrochloride :: Sarcodoxome :: Treatment of soft tissue sarcomas :: 27-12-2006 :: GP-Pharm SA :: Pol. Ind. Els Vinyets els Fogars n 2, :: Quinti de Mediona :: Barcelona :: SPAINliposomal gadodiamide :: Treatment of glioma. :: 12-11-2008 :: MedGenesis Therapeutix, Inc. :: 730-730 View Street :: Victoria, BC V8W 3Y7 :: CANADALiposomal N-Acetylglucosminyl-N-Acetylmuramly-L-Ala-D-isoGln-L-Ala -gylcerolidpalmitoyl :: ImmTher :: Treatment of osteosarcoma. :: 10-06-1998 :: Endorex Corp. :: 900 North Shore Drive :: Lake Bluff IL 60044Liposomal N-Acetylglucosminyl-N-Acetylmuramly-L-Ala-D-isoGln-L-Ala -gylcerolidpalmitoyl :: ImmTher :: Treatment of Ewing's sarcoma. :: 10-06-1998 :: Endorex Corp. :: 900 North Shore Drive :: Lake Bluff IL 60044Liposomal nystatin :: Nyotran :: Treatment of invasive fungal infections. :: 13-06-2000 :: The University of Texas :: M.D. Anderson Cancer Center :: Unit 038 :: Houston TX 77030 liposomal p-ethoxy growth receptor bound protein-2 antisense product :: Treatment of chronic myelogenous leukemia :: 05-12-2003 :: Bio-Path, Inc. :: 3293 Harrison Blvd., Suite 230 :: Ogden UT 84403Liposomal prostaglandin E1 injection :: Treatment of acute respiratory distress syndrome. :: 25-04-1996 :: Liposome Company, Inc. :: One Research Way :: Princeton NJ 08540liposomal topotecan hydrochloride :: Treatment of gliomas :: 30-10-2008 :: MedGenesis Therapeutix, Inc. :: 730-730-View Street :: Victoria, BC, V8W 3Y7 :: CANADALiposomal-cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane-Pt (II) :: Aroplatin :: Treatment of malignant mesothelioma. :: 01-09-1999 :: Antigenics Incorporated :: 3 Forbes Road :: Lexington MA 02421Liposome encapsulated recombinant interleukin-2 :: Treatment of brain and CNS tumors. :: 25-11-1991 :: Oncothyreon Canada, Inc. :: 2011-94 St., NW :: Suite 200 :: CANADALiposome encapsulated recombinant interleukin-2 :: Treatment of cancers of the kidney and renal pelvis :: 20-06-1994 :: Oncothyreon Canada, Inc. :: 2011 – 94th Street NW :: 200 Edmonston, AB :: CANADALisofylline :: Treatment of patients undergoing induction therapy for acute myeloid leukemia. :: 10-06-1999 :: Cell Therapeutics, Inc. :: 201 Elliot Avenue West201 :: Suite 400 :: Seattle WA 98119 L-leucovorin :: Isovorin :: For use in combination chemotherapy with the approved agent 5-fluorouracil in the palliative treatment of metastatic adenocarcinoma of the colon and rectum. :: 18-12-1990 :: Spectrum Pharmaceuticals, Inc. :: 157 Technology Drive :: Irvine CA 92618Loxoribine :: Treatment of common variable immunodeficiency. :: 24-02-1992 :: R. W. Johnson Pharmaceutical Research Institute :: Route 202, P.O. Box 300 :: Raritan NJ 08869L-threonine :: Treatment of spasticity associated with familial spastic paraparesis. :: 24-07-1992 :: Interneuron Pharmaceuticals, Inc. :: 99 Hayden Ave., Suite 200 :: Lexington MA 02421-7966 L-threonine :: Threostat :: Treatment of amyotrophic lateral sclerosis. :: 06-02-1989 :: Tyson And Associates :: 12832 Chadron Avenue :: Hawthorne CA 90250L-threonyl-L-prolyl-L-prolyl-L-threonine :: Treatment of neuropathic pain associated with spinal cord injury :: 26-04-2005 :: Nyxis Neurotherapies, Inc. :: 1801 Maple Avenue :: Suite 4300 :: Evanston IL 60201 L-tyrosine-L-serine-L-leucine :: CMS-024 :: Treatment of hepatocellular carcinoma. :: 10-09-2004 :: CMS Peptides Patent Holding Company Limited :: Unit 2106, 21st Floor, Island Place Tower :: 510 King's Rd :: North Point :: HONG KONGLucinactant :: Surfaxin :: Prevention of bronchopulmonary dysplasia in premature infants :: 23-05-2006 :: Discovery Laboratories, Inc :: 2600 Kelly Road :: Warrington PA 18976Lucinactant :: Surfaxin :: Treatment of bronchopulmonary dysplasia in premature infants. :: 21-10-2005 :: Discovery Laboratories, Inc. :: 2600 Kelly Road :: Warrington PA 18976Lucinactant :: Surfaxin :: Treatment of meconium aspiration syndrome in newborn infants :: 30-07-1996 :: Discovery Laboratories, Inc. :: 2600 Kelly Road :: Warrington PA 18976Lucinactant :: Surfaxin :: Treatment of acute respiratory distress syndrome in adults. :: 17-07-1995 :: Discovery Laboratories, Inc. :: 2600 Kelly Road :: Warrington PA 18976Lucinactant :: Surfaxin :: Treatment of respiratory distress syndrome in premature infants. :: 18-10-1995 :: Discovery Laboratories, Inc. :: 2600 Kelly Road :: Warrington PA 18976Lysine acetylsalicylate injectable :: Treatment of pain and fever secondary to sickle cell disease crisis. :: 01-08-1989 :: G.D. Searle & Company :: 4901 Searle Parkway :: Skokie IL 60077lysosomal enzyme N-acetylgalactosamine-6-sulfate sulfatase :: Treatment of mucopolysaccharidosis Type IVA (Morquio Syndrome) :: 10-09-2008 :: Vivendy Therapeutics LTD :: Peter Merian -Strasse 45 :: SWITZERLANDlyso-thermosensitive lipsomal doxorubicin :: ThermoDox (r) :: For treatment of hepatocellular carcinoma. :: 17-03-2009 :: Celsion Corpora tion :: 10220-L Old Columbia Road :: Columbia MD 21046macitentan :: Treatment of idiopathic pulmonary fibrosis. :: 14-04-2009 :: Actelion Pharmaceuticals Ltd. :: Gewerbestrasse 16 :: SWITZERLANDMafosfamide :: Treatment of neoplastic meningitis :: 21-01-2003 :: Baxter Healthcare Corporation :: Route 120 & Wilson Road :: Round Lake IL 60073-0490 MAGE-A3 cancer therapeutic Trojan peptide vaccine :: Treatment of MAGE-A3 expressing head and neck squamous cell carcinoma :: 24-11-2008 :: Gliknik, Inc. :: 801 W. Baltimore Street :: Baltimore MD 21201Mammalian target of rapamcyin (mTOR) inhibitor :: Treatment of soft tissue sarcoma :: 12-08-2005 :: ARIAD Pharmaceuticals, Inc :: 26 Landsdowne Street :: Cambridge MA 02139-4234 Manganese superoxide dismutase mimetic :: Prevention of radiation- or chemotherapy-induced oral mucositis in cancer patients :: 27-02-2008 :: ActivBiotics, Inc. :: 110 Hartwell Avenue :: Lexington MA 02421Mannitol :: Bronchitol :: For use to facilitate clearance of mucus in patients with bronchiectasis and in patients with cystic fibrosis at risk for bronchiectasis :: 11-02-2005 :: Pharmaxis Ltd. :: 10 Rodborough Rd. :: NSW 2086 :: AUSTRALIAmannopentaose phosphate sulfate :: Treatment of high-risk Stage II, Stage III, and Stage IV melanoma :: 27-04-2004 :: Progen Industries Limited :: P. O. Box 28 :: Richlands 4077 :: AUSTRALIAmaribavir :: Prevention of cytomegalovirus viremia and disease in the populations at risk. :: 01-02-2007 :: ViroPharma Inc. :: 730 Stockton Drive :: Exton PA 19341Marijuana :: Treatment of HIV-associated wasting syndrome. :: 25-05-1999 :: Multidisciplinary Association for Psychedelic Studies, Inc. :: 3 Francis St. :: Belmont MA 02478Matrix metalloproteinase inhibitor :: Galardin :: Treatment of corneal ulcers. :: 05-12-1991 :: Glycomed, Inc :: 860 Atlantic Avenue :: Alameda CA 94501MaxAdFVIII :: Treatment of Hemophilia A :: 03-03-2003 :: GenStar Therapeutics Corporation :: 10865 Altman Row :: Suite 200 :: San Diego CA 92121-1113Mazindol :: Sanorex :: Treatment of Duchenne muscular dystrophy. :: 08-12-1986 :: Collipp, Platon J. M.D. :: 176 Memorial Drive :: Jesup GA 31545Mecamylamine :: Inversine :: Treatment of Tourette's syndrome. :: 14-10-1998 :: Targacept, Inc. :: 200 East First St. :: Suite 300 :: Winston-Salem NC 27101-4165mecasermin :: Iplex :: Treatment of myotonic dystrophy :: 03-12-2007 :: Insmed, Inc. :: 8720 Stony Point Parkway :: Richmond VA 23235Mecasermin :: Myotrophin :: Treatment of amyotrophic lateral sclerosis. :: 05-08-1991 :: Cephalon, Inc. :: 41 Moores Road :: P. O. Box 4011 :: Frazer PA 19355 meclorethamine or nitrogen mustard :: Treatment of mycosis fungoides. :: 12-08-2004 :: Yaupon Therapeutics, Inc. :: 259 Radnor Chester Road :: Radnor PA 19087MEDI-522 :: Vitaxin :: For the treatment of of stage IIb, stage IIc, stage III and stage IV melanoma :: 14-04-2004 :: MedImmune, LLC :: One MedImmune Way :: Gaithersburg MD 20878Medroxyprogesterone acetate :: Hematrol :: Treatment of immune thrombocytopenic purpura. :: 22-02-2001 :: ZaBeCor Pharmaceutical Company, LLC :: 821 Westview Street :: Philadelphia PA 19119Mefloquine HCl :: Mephaquin :: Prevention of chloroquine-resistant Falciparum malaria. :: 22-07-1987 :: Mepha AG :: 4143 Dornach :: POSTFASH 137 :: SWITZERLANDMefloquine HCl :: Mephaquin :: Treatment of chloroquine-resistant Falciparummalaria. :: 22-07-1987 :: Mepha AG :: 4143 Dornach :: POSTFASH 137 :: SWITZERLANDMelanoma autologous dendritic cell vaccine :: Treatment of stage IIIb through IV metastatic melanoma :: 06-09-2006 :: Hoag Memorial Hospital Presbyterian :: Hoag Cancer Center Cell Biology Laboratory :: Building 41 :: Newport Beach CA 92658 Melanoma cell vaccine :: Canvaxin :: Treatment of invasive melanoma. :: 13-10-1994 :: CancerVax Corporation :: 2110 Rutherford Road :: Carlsbad CA 92008Melanoma peptide vaccine :: Treatment of HLA-A2+ patients with stage IIB, IIC, III, and IV malignant melanoma :: 29-03-2005 :: Bristol-Myers Squibb Research Inst :: 5 Research Parkway :: P. O. Box 5100 :: Wallingford CT 06492 Melanoma vaccine :: Melacine :: Treatment of stage III – IV melanoma. :: 20-12-1989 :: Ribi ImmunoChem Research, Inc. :: 533 Old Corvallis Road :: Hamilton MT 59840Melatonin :: Circadin :: Treatment of non-24-hour sleep-wake disorder in blind individuals without light perception :: 09-07-2004 :: Neurim Pharmaceuticals, Ltd. :: 8 Hanechoshet St. :: Tel-Aviv :: ISRAELMelatonin :: Treatment of circadian rhythm sleep disorders in blind people with no light perception. :: 15-11-1993 :: Sack, Robert, M.D. :: Oregon Health Sciences University :: 3181 S.W. Sam Jackson Park Road :: Portland OR 97201 melphalan :: High dose conditioning treatment prior to hematopoietic progenitor (stem) cell transplantation :: 24-11-2008 :: CyDex Pharmaceuticals, Inc. :: 10513 W. 84th Terrace :: Lenexa KS 66214Melphalan :: Alkeran for Injection :: For use in hyperthermic regional limb perfusion to treat metastatic melanoma of the extremity. :: 03-03-1992 :: Glaxo Wellcome Research and Development :: 5 Moore Drive :: PO Box 13398 :: Research Triangle Park NC 27709 melphalan hydrochloride :: Treatment of patients with ocular (uveal) melanoma. :: 12-11-2008 :: Delcath Systems, Inc. :: Rockefeller Center :: New York NY 10020melphalan hydrochloride :: Treatment of patients with cutaneous melanoma. :: 12-11-2008 :: Delcath Systems, Inc. :: Rockefeller Center :: 23rd Floor :: New York NY 10020 mepivacaine :: Treatment of postherpetic neuralgia :: 08-01-2007 :: Cinergen, LLC :: 146 Medinah Drive :: Blue Bell PA 19422-3212 Mepivacaine :: Treatment of painful HIV-associated neuropathy :: 18-10-2006 :: Cinergen :: 146 Medinah Drive :: Blue Bell PA 19422-3212 mepolizumab :: For first-line treatment in patients with hypereosinophilic syndrome :: 28-05-2004 :: GlaxoSmithKline Pharmaceuticals :: P.O. Box 7929 :: Philadelphia PA 19101Meropenem :: Merrem IV :: Management of acute pulmonary exacerbations, in cystic fibrosis patients, due to respiratory tract infection with susceptible organisms. :: 27-04-2000 :: AstraZeneca Pharmaceuticals :: 1800 Concord Pike :: PO Box 15437 :: Wilmington DE 19850-5437 :: mesalamine; 5-aminosalicylic acid :: Lialda :: Treatment of active, mild to moderate ulcerative colitis in children 5 to 17 years :: 27-02-2008 :: Shire :: 725 Chesterbrook Blvd. :: Wayne PA 19087-5637 Mesna :: Inhibition of the urotoxic effects induced by oxazaphosphorine compounds such as cyclophosphamide. :: 16-12-1987 :: Asta Medica , Inc. :: 890 East St. :: Tewksbury MA 01876-1496 Methionine/L-methionine :: Treatment of AIDS myelopathy. :: 21-08-1996 :: Genopia USA, Inc. :: 90 Gold Street, 6N :: New York NY 10038methotrexate :: Rheumatrex :: Treatment of juvenile rheumatoid arthritis. :: 23-08-1993 :: Wyeth-Ayerst Laboratories :: P.O. Box 8299 :: Philadelphia PA 19101-8299 Methotrexate with laurocapram :: Methotrexate/azone :: Topical treatment of mycosis fungoides. :: 15-10-1990 :: Echo Therapeutics, Ltd. :: 10 Forge Parkway :: Franklin MA 02038Methoxsalen :: Uvadex :: For use in conjunction with the UVAR photopheresis system to treat graft versus host disease. :: 14-10-1998 :: Therakos, Inc. :: 437 Creamery Way :: Exton PA 19431metreleptin :: Treatment of metabolic disorders secondary to lipodystrophy :: 22-08-2001 :: Amylin Pharmaceuticals, Inc. :: 9360 Towne Centre Drive :: San Diego CA 92121metreleptin :: "Treatment of leptin deficiency secondary to generalizedlipodystrophy and partial familial lipodystrophy" :: 22-08-2001 :: Amylin Pharmaceuticals, Inc. :: 9360 Towne Center Drive :: San Diego CA 92121metronidazole :: Treatment of pouchitis :: 17-09-2008 :: Formac Pharmaceuticals, NV :: Gaston Geenslaan 1 :: BELGIUMMetronidazole :: Metrogel :: Treatment of perioral dermatitis. :: 24-10-1991 :: Galderma Laboratories, Inc. :: P.O. Box 331329 :: Fort Worth TX 76163Metronidazole (topical) :: Flagyl :: Treatment of grade III and IV, anaerobically infected, decubitus ulcers. :: 24-11-1987 :: Searle :: 4901 Searle Parkway :: Skokie IL 60077Metronidazole 10% ointment :: Topical treatment of active perianal Crohn's disease :: 08-11-2007 :: S.L.A. Pharma (UK) Ltd :: Elite House :: Leavesden :: Watford WD25 7SA :: UNITED KINGDOMmetyrosine :: Demser :: Treatment of velocardiofacial syndrome associated psychosis. :: 25-07-2008 :: Aton Pharma, Inc. :: 3150 Brunswick Place :: Lawrenceville NJ 08648mibefradil :: Treatment of pancreatic cancer. :: 16-10-2008 :: Tau Therapeutics, LLC :: 2988 Cove Trace :: Charlottesville VA 22911Mibefradil :: Treatment of ovarian cancer :: 15-06-2007 :: Tau Therapeutics, LLC :: 2988 Cove Trace :: Charlottesville VA 22911Microbubble contrast agent :: Filmix Neurosonographic Contrast Agent :: Intraoperative aid in the identification and localization of intracranial tumors. :: 16-11-1990 :: Cav-Con, Inc. :: 55 Knollwood Road :: Farmington CT 06032Microvesiculated modified glycosylated tissue factor :: Treatment of cutaneous bleeding episodes in patients with von Willebrand disease. :: 11-10-2007 :: Thrombotargets Corp. :: 2530 Meridian Parkway :: Durham NC 27713Microvesiculated modified glycosylated tissue factor :: Treatment of non-life threatening, mild to severe bleeding episodes due to cutaneous injuries or dental procedures in hemophiliac patients :: 25-01-2007 :: Thrombotargets Corp. :: 2530 Meridian Parkway :: Suite 3023 :: Durham NC 27713 Midazolam HCl :: Treatment of bouts of increased seizure activity in selected refractory patients with epilepsy who are on stable regimens of anti-epileptic drugs and who require intermittent use of midazolam :: 08-05-2006 :: Schwarz Biosciences, Inc. :: 8010 Arco Corporate Drive :: Raleigh NC 27617mifamuritide :: Junovan :: Treatment of osteosarcoma :: 05-06-2001 :: Immuno-Designed Molecules :: 9 Parker :: Irvine CA 92618-1605 Mifepristone :: Treatment of Cushing's syndrome secondary to ectopic ACTH secretion :: 07-02-2005 :: HRA Pharma :: 15 , rue Beranger :: 75003 Paris :: FRANCEmifepristone :: Corlux :: Treatment of the clinical manifestations of endogenous Cushing's symdrome. :: 05-07-2007 :: Corcept Therapeutics, Inc. :: 149 Commonwealth Drive :: Menlo Park CA 94025miglustat :: Zavesca (r) :: Treatment of the neurological manifestations of Niemann-Pick disease,type C. :: 12-11-2008 :: Actelion Pharmaceuticals Ltd :: Innovation Centre :: CH-4123, Allschwil :: SWITZERLANDmilatuzumab :: Treatment of chronic lymphocytic leukemia. :: 24-06-2008 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950milatuzumab :: Treatment of multiple myeloma :: 10-03-2008 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950miltefosine :: Miltex(r) / Impavido(r) :: Topical treatment of cutaneous lymphoma encompassing cutaneous manifestations of T-cell lymphoma and B-cell lymphoma :: 18-03-2009 :: ExperGen Drug Development GmbH :: Hernalser Haupstrasse 24/16 :: AUSTRIAmiltefosine :: Impavido :: Treatment of leishmaniasis. :: 10-10-2006 :: Paladin Labs (USA), Inc. :: 160 Greentree Drive :: Suite 101 :: Dover DE 19904 Minocycline HCl :: Minocin Intravenous :: Treatment of chronic malignant pleural effusion. :: 19-06-1992 :: Lederle Laboratories Division :: Division of American Cyanamid Company :: 401 N. Middletown Road :: Pearl River NY 10965 Minocycline hydrochloride :: Treatment of sarcoidosis :: 28-03-2006 :: Autoimmunity Research Foundation :: Autoimmunity Research, Inc. :: Thousand Oaks CA 91360misoprostol :: GyMiso :: Treatment of intrauterine fetal death not accompanied by complete expulsion of the products of conception in the second and third trimesters of pregnancy. :: 10-01-2005 :: Gynuity Health Projects, LLC :: 15 East 26th Street :: New York NY 10010Mitoguazone :: apep :: Treatment of diffuse non-Hodgkin's lymphoma, including AIDS-related diffuse non-Hodgkin's lymphoma. :: 18-03-1994 :: ILEX Oncology, Inc. :: 4545 Horizon Hill Blvd. :: San Antonio TX 78229-2263 Mitolactol :: "Treatment of invasive carcinoma of the uterine cervix" :: 23-01-1989 :: Biopharmaceutics, Inc. :: 990 Station Road :: Bellport NY 11713Mitolactol :: As adjuvant therapy in the treatment of primary brain tumors. :: 12-07-1995 :: Biopharmaceutics, Inc. :: 990 Station Road :: Bellport NY 11713mitomycin-C :: Trabomycin :: Treatment of refractory glaucoma as an adjunct to ab externo glaucoma surgery. :: 08-01-2008 :: Mobius Therapeutics, Inc. :: 743 Spirit 40 Park Drive :: Chesterfield MO 63005Mitomycin-C :: Treatment of refractory glaucoma as an adjunct to ab externo glaucoma surgery. :: 20-08-1993 :: IOP Inc. :: 3100 Airway Avenue, Suite 106 :: Costa Mesa CA 92626MN14 monoclonal antibody to carcinoembryonic antigen :: Cea-Cide :: Treatment of small cell lung cancer :: 18-09-1998 :: Immunomedics, Inc. :: 300 American Rd. :: Morris Plains NJ 07950MN14 monoclonal antibody to carcinoembryonic antigen :: Cea-Cide :: Treatment of pancreatic cancer. :: 24-11-1998 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Molgramostim :: Leucomax :: Treatment of AIDS patients with neutropenia due to the disease, AZTor ganciclovir. :: 24-01-1989 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Molgramostim :: Leucomax :: Treatment of aplastic anemia. :: 25-09-1989 :: Schering Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07033monarsen :: Treatment of Myasthenia Gravis :: 14-11-2003 :: Ester Neurosciences Ltd. :: Ackerstein Towers, Bldg B, 10th Floor :: 11 HaManoflm St. :: ISRAELMonoclonal Ab(murine) anti-idiotype melanoma-associated antigen :: Melimmune :: Treatment of invasive cutaneous melanoma. :: 19-09-1994 :: IDEC Pharmaceuticals Corporation :: 3030 Callan Road :: San Diego CA 92121Monoclonal antibodies (murine or human) to B-cell lymphoma :: Treatment of B-cell lymphoma. :: 06-05-1986 :: IDEC Pharmaceuticals Corporation :: 11011 Torreyana Road :: San Diego CA 92121Monoclonal antibody 17-1a :: Panorex :: Treatment of pancreatic cancer. :: 04-04-1988 :: Centocor, Inc. :: 244 Great Valley Parkway :: Malvern PA 19355monoclonal antibody 3F8 :: Treatment of neuroblastoma :: 16-09-2008 :: United Therapeutics Corporation :: PO Box 14186 :: One Park Drive :: Research Triangle Park NC 27709 Monoclonal antibody for immunization against lupus nephritis :: Treatment of lupus nephritis. :: 07-01-1993 :: VivoRx Autoimmune, Inc. :: 2825 Santa Monica Blvd., Suite 200 :: Santa Monica CA 90404Monoclonal antibody to cytomegalovirus (human) :: Treatment of cytomegalovirus retinitis in patients with AIDS. :: 15-11-1991 :: Protein Design Labs, Inc. :: 2375 Garcia Avenue :: Mountain View CA 94043Monoclonal antibody to cytomegalovirus (human) :: Prophylaxis of cytomegalovirus disease in patients undergoing solid organ transplantation. :: 13-09-1991 :: Protein Design Labs, Inc. :: 2375 Garcia Avenue :: Mountain View CA 94043Monoclonal antibody to hepatitis B virus (human) :: Prophylaxis of hepatitis B reinfection in patients undergoing liver transplantation secondary to end-stage chronic hepatitis B infection. :: 17-06-1991 :: Protein Design Labs, Inc. :: 34801 Campus Dr. :: Fremont CA 94555Monoclonal antibody-B43.13 :: Ovarex MAb-B43.13 :: Treatment of epithelial ovarian cancer. :: 25-11-1996 :: ViRexx Medical Corporation :: 8223 Roper Road :: Edmonton :: CANADAMonoclonal antiendotoxin antibody XMMEn-0e5 :: Treatment of patients with gram-negative sepsis which has progressed to shock. :: 04-11-1985 :: Pfizer, Inc. :: 235 East 42nd Street :: New York NY 10017Monolaurin :: Glylorin :: Treatment of congenital primary ichthyosis. :: 29-04-1993 :: Glaxo Wellcome Inc. :: 5 Moore Drive :: PO Box 13398 :: Research Triangle Park NC 27709 motexafin gadolinium :: Xcytrin :: For use in conjunction with whole brain radiation for the treatment of brain metastases arising from solid tumors :: 27-01-2003 :: Pharmacyclics, Inc. :: 999 East Arques Avenue :: Sunnyvale CA 94085-4521 MTC-DOX for Injection :: Treatment of hepatocellular carcinoma :: 03-01-2001 :: FeRx Incorporated :: 4330 La Jolla Village Drive :: Suite #250 :: San Diego CA 92122 Mucoid exopolysaccharide Pseudomonas hyperimmune globulin :: MEP IGIV :: Treatment of pulmonary infections due to Pseudomonas aeruginosa in patients with cystic fibrosis. :: 09-01-1991 :: North American Biologicals, Inc. :: 12280 Wilkins Avenue :: Rockville MD 20852 :: Mucoid exopolysaccharide Pseudomonas hyperimmune globulin :: MEP IGIV :: Prevention of pulmonary infections due to Pseudomonas aeruginosa in patients with cystic fibrosis. :: 07-11-1990 :: North American Biologicals, Inc. :: 12280 Wilkins Avenue :: Rockville MD 20852Multi-ligand somatostatin analogue :: Treatment of patients with functional gastroenteropancreatic (GEP) neuroendocrine tumors (specifically, carcinoid, insulinoma, gastrinoma, somastatinoma, GRFoma, VIPoma and glucagonoma. :: 27-07-2004 :: Novartis Pharmaceuticals Corporation :: One Health Plaza :: East Hanover NJ 07936-1080 Multi-vitamin infusion (neonatal formula) :: For establishment and maintenance of total parenteral nutrition in very low birth weight infants. :: 12-12-1989 :: Astra Pharmaceuticals, L.P. :: 725 Chesterbrook Blvd. :: Wayne PA 19087-5677 Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma :: Oncolym :: Treatment of B-cell non-Hodgkin's lymphoma. :: 27-11-1998 :: Peregrine Pharmaceuticals, Inc. :: 14272 Franklin Ave. :: Suite 100 :: Tustin CA 92780 Murine MAb to polymorphic epithelial mucin, human milk fat globule 1 :: Theragyn :: Adjuvant treatment of ovarian cancer. :: 22-03-1999 :: Antisoma plc :: West Africa House :: Hanger Lane Ealing :: London W5 3QR :: UNITED KINGDOMMx-dnG1 :: Rexin-G(R) :: Treatment for soft tissue sarcoma. :: 24-06-2008 :: Epeius Biotechnologies Corporation :: 475 Huntington Drive :: San Marino CA 91108Mx-dnG1 :: Rexin-G :: Treatment of osteosarcoma. :: 24-06-2008 :: Epeius Biotechnologies Corporation :: 475 Huntington Drive :: San Marino CA 91108Mx-dnG1 or Rexin-G retroviral vector :: REXIN-G :: Treatment of pancreatic cancer :: 15-08-2003 :: Epeius Biotechnologies Corporation :: 345 Pioneer Drive, 1803W :: Glendale CA 91203Mycobacterium avium sensitin RS-10 :: For use in the diagnosis of invasive Mycobacterium avium disease in immunocompetent individuals. :: 11-10-1995 :: Statens Seruminstitut :: 5 Artillerivej :: DK-2300 Copenhagen S :: SWEDENMycophenolate mofetil :: CellCept :: Treatment of pemphigus vulgaris :: 26-05-2006 :: Hoffman-La Roche, Inc. :: 340 Kingsland Street :: Nutley NJ 07110Myelin :: Treatment of multiple sclerosis. :: 27-06-1991 :: AutoImmune, Inc. :: 128 Spring Street :: Lexington MA 02173myo-inositol :: Prevention of retinopathy of prematurity in preterm infants at risk for developing retinopathy of prematurity :: 07-04-2005 :: Abbott Nutrition :: Abbott Laboratories :: 625 Cleveland Ave. :: Columbus OH 43215-1724myristoylated recombinant SCR1-3 of human complement reseptor type I :: APT070 :: Prevention of delayed graft function in solid organ transplant :: 21-05-2003 :: Orexo AB :: Box 303 :: Virdings alle 32 A :: SWEDENN-((methyl-diazacyclohexyl-methylbenzamide)-asaphenyl-aminothiopyrrole) mesylate :: Treatment of malignant gastrointestinal stromal tumors. :: 20-04-2005 :: AB Science :: 3, avenue George V :: FRANCEN-(2,2,2-trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide, methane-sulfonate salt :: Treatment of homozygous familial hypercholesterolemia :: 23-10-2007 :: Aegerion Pharmaceuticals, Inc. :: Center Pointe IV :: Suite 304 :: Bridgewater NJ 08807 N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide, phosphate (1:2) :: Treatment of gastrointestinal stromal tumors :: 13-01-2005 :: Amgen, Inc. :: One Amgen Center Drive :: Thousand Oaks CA 91320-1799 N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-1,4-dihydro-4-oxoquinoline-3-carboxamide :: Treatment of patients with cystic fibrosis. :: 20-12-2006 :: Vertex Pharmaceuticals, Inc. :: 130 Waverly St. :: Cambridge MA 02139-4242 N-(2-amino-phenyl)-4-[(4-pyridin-3-yl-pyrimidin-2-ylamino)-methyl] benzamide dihydrobromide :: Treatment of Hodgkin's lymphoma :: 08-08-2007 :: MethylGene :: 7220 Frederick Banting :: St. Laurant :: CANADAN-(2-amino-phenyl)-4-[(4-pyridin-3-yl-pyrimidin-2-ylamino)-methyl] benzamide dihydrobromide :: Treatment of acute myeloid leukemia :: 01-02-2008 :: MethylGene :: 7220 Frederick Banting :: Quebec H4S 2A1 :: CANADAN-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-(morpholin-4-yl)ethoxy) imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea di-hydrochloride salt :: Treatment of acute myeloid leukemia :: 18-03-2009 :: Ambit Biosciences Corporation :: 4215 Sorrento Valley Boulevard :: San Diego CA 92121N-(methyl-diazacyclohexyl-methylbenzamide)-azaphenyl-aminothiopyrrole) mesylate :: Treatment of multiple myeloma. :: 17-10-2005 :: AB Science :: 3, avenue George V :: FRANCEN-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide :: Treatment of neuroblastoma :: 30-09-2004 :: Abbott Laboratories :: Pharmaceuticals Products Division :: D-491, AP30-1E :: Abbott Park IL 60064-6157N-[3-(4',5'-bipyrimidin-2-ylamino)-4-methylphenyl]-4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]methyl}-3-(trifluoromethyl)benzamide :: Treatment of Philadelphia chromosome-positive chronic myelogenous leukemia. :: 27-12-2006 :: CytRx Corporation :: 3030 Bunker Hill Street :: Suite 101 :: San Diego CA 92109 N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N1-(2-fluoro-5-methylphenyl) urea :: Treatment of acute myelogenous leukemia :: 23-10-2007 :: Abbott Laboratories :: Global Pharmaceuticals Research & Development :: 200 Abbott Park Road :: Abbott Park IL 60064-6157N-[4-(3-amino1H-indazol-4-yl)phenyl]-N1-(2-fluoro-5-methylphenyl)urea :: Treatment of hepatocellular carcinoma :: 23-05-2007 :: Abbott Laboratories :: Global Pharmaceuticals Research & Development :: 200 Abbott Park Road :: Abbott Park IL 60064-6157N-[4-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide :: Treatment of stages IIB-IV melanoma :: 13-08-2004 :: Coley Pharmaceuticals Group, Inc. :: 93 Worcester Street :: Suite 101 :: Wellesley MA 02481 N-[4-(4-amino-2-ethyl-lH-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide :: Treatment of cutaneous T-cell lymphoma :: 24-03-2006 :: Pfizer, Inc. :: 50 Pequot Avenue :: 6025-A3106 :: New London CT 06320 N-[4-bromo-2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-N'-[3,5-bis(trifluoromethyl)phenyl]urea :: Treatment of sickle cell disease :: 13-05-2002 :: NeuroSearch A/S :: 93 Pederstrupvej :: DK-2750 Ballerup :: DENMARKN2'-Deacetyl-N2'-[4-methyl-4-(oxobuthyldithio)-1-oxopentyl]-maytansine-chimerized anti-CD138 IgG4 Monoclonal Antibody :: Treatment of multiple myeloma :: 27-02-2008 :: Biotest Pharmaceuticals Corporation :: 5800 Park of Commerce Blvd., NW :: Boca Raton FL 33487nabumetone :: For treatment of pediatric juvenile rheumatoid arthritis. :: 05-05-2008 :: Cook Pharma :: 109 Graylyn Drive :: Chapel Hill NC 27516N-acetylcysteinate Lysine :: Nacystelyn Dry Powder Inhaler :: For the management of cystic fibrosis :: 27-12-2000 :: Galephar 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Lee, MD, FACP :: University of Texas Southwestern Medical Center at :: 5323 Harry Hines Blvd :: Dallas TX 75390-9151N-acetyl-glucosamine thiazoline :: Treatment of adult Tay-Sachs disease :: 06-02-2006 :: ExSAR Corporation :: 11 Deer Park Drive :: Monmouth Junction NJ 08852N-acetylprocainamide :: Napa :: To lower the defibrillation energy requirement sufficiently to allow automatic implantable cardioverter defibrillator therapy in those patients who could otherwise not use the device. :: 23-03-1990 :: Medco Research, Inc. :: 8455 Beverly Blvd. :: Suite 308 :: Los Angeles CA 90048 N-acetyl-procainamide :: Prevention of life-threatening ventricular arrhythmias in patients with documented procainamide-induced lupus. :: 10-12-1996 :: NAPA of the Bahamas :: 3560 Pennsylvania Avenue, Suite 7 :: Dubuque IA 52002N-acetyl-sarcosyl-glycyl-L-valyl-D-alloisoleucyl-L-threonyl-L-norvalyl-L-isoleucyl-L-arginyl_L-prolylethylaminde acetate :: Treatment of soft tissue sarcoma :: 09-12-2003 :: Abbott Laboratories :: Pharmaceutical Products Division :: 200 Abbott Park Road :: Abbott Park IL 60064 N-adamantanyl-N'-Geranyl-ethylenediamine :: Treatment of tuberculosis. :: 16-10-2007 :: Sequella, Inc. :: 9610 Medical Center Drive :: Rockville MD 20850natural human lymphoblastoid interferon-alpha :: Treatment of polycythemia vera :: 18-11-2002 :: Amarillo Biosciences, Inc. :: 4134 Business Park Drive :: Amarillo TX 79110Natural human lymphoblastoid interferon-alpha :: Treatment of Behcet's disease. :: 18-01-2000 :: Amarillo Biosciences, Inc. :: 4134 Business Park Drive :: Amarillo TX 79110Natural human lymphoblastoid interferon-alpha :: Treatment of papillomavirus warts in the oral cavity of HIV positive patients. :: 10-08-2000 :: Amarillo Biosciences, Inc. :: 4134 Business Park Drive :: Amarillo TX 79110NDROGE :: Treatment of postanoxic intention myoclonus. :: 01-11-1984 :: WATSON Laboratories, Inc. :: 33 Ralph Avenue :: P.O. Box 30 :: Copiaque NY 11726-0030Nebacumab :: Centoxin :: Treatment of patients with gram-negative bacteremia which has progressed to endotoxin shock. :: 01-10-1986 :: Centocor, Inc. :: 200 Great Valley Parkway :: Malvern PA 19355Neurotrophin-1 :: Treatment of motor neuron disease/amyotrophic lateral sclerosis. :: 13-09-1994 :: Ericsson, Arthur Dale, M.D. :: 6560 Fannin, Scurlock Tower, Suite 720 :: Houston TX 77303NG-29 :: Somatrel :: Diagnostic measure of the capacity of the pituitary gland to release growth hormone. :: 08-08-1989 :: Ferring Laboratories, Inc. :: 400 Rella Boulevard, Suite 201 :: Suffern NY 10901Nifedipine :: Treatment of interstitial cystitis. :: 13-06-1991 :: Fleischmann, Jonathan M.D. :: MetroHealth Medical Center :: 3395 Scranton Road :: Cleveland OH 44109 Nikkomycin Z :: Treatment of coccidioidomycosis :: 14-02-2006 :: Valley Fever Center for Excellence (1-111 INF) :: University of Arizona :: Tucson AZ 85723nilotinib :: Tasigna :: Treatment of gastrointestinal stromal tumors. :: 20-03-2007 :: Novartis Pharmaeuticals Corporation :: One Health Plaza :: East Hanover NJ 07936-1080 Nimotuzumab :: Treatment of glioma :: 17-11-2004 :: YM Biosciences Inc. :: 5045 Orbitor Drive :: Mississauga, Ontario L4W 4Y4 :: CANADAniprisan :: Hemoxin :: Treatment of sickle cell disease :: 15-08-2003 :: Xechem International, Inc. :: 379 Thornall Street :: Edison NJ 08837nitazoxanide :: Cryptaz :: Treatment for intestinal amebiasis :: 23-10-2001 :: Romark Laboratories, L.C. :: 6200 Courtney Campbell Causeway :: Suite 880 :: Tampa FL 33607 Nitisinone :: Orfadin :: Treatment of alkaptonuria :: 19-10-2001 :: Swedish Orphan AB :: Kungsgatan 37, 7th Floor :: SE-111 56 :: SWEDENnitric oxide :: INOmax (r) :: Use in combination with a drug delivery device for acute treatment of sickle cell vaso-occlusive crisis (pain crises) :: 05-09-2008 :: INO Therapeutics :: 6 Route 173 :: Clinton NJ 08809Nitric oxide :: Diagnosis of sarcoidosis :: 16-02-2005 :: SensorMedics Corporation :: 22705 Savi Ranch Parkway :: Yorba Linda CA 92887-4645 Nitric oxide :: INOmax :: To reduce the risk of chronic lung disease in premature neonates :: 27-09-2004 :: INO Therapeutics :: 6 Route 173 :: Clinton NJ 08809Nitric oxide :: Treatment of acute respiratory distress syndrome in adults. :: 10-07-1995 :: INO Therapeutics, Inc. :: 54 Old Highway 22 :: Clinton NJ 08809Nitroprusside :: Treatment and prevention of cerebral vasospasm following subarachnoid hemorrhage. :: 21-02-2001 :: Thomas, MD, Jeffrey Evan :: Thomas Jefferson University and Wills Neurosensory :: 834 Walnut Street, Suite 650 :: Philadelphia PA 19107-5102N-malonyl-bis(N'-methyl-N'-thiobenzoylhydrazide) :: Treatment of metastatic melanoma in combination with paclitaxel :: 18-12-2007 :: Synta Pharmaceuticals Corporation :: 45 Hartwell Ave. :: Lexington MA 02421N-Methyl-2-[3-[((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]benzamide :: Axitinib :: Treatment of follicular, medullary and anaplastic thyroid carcinoma and metastatic or locally advanced papillary thyroid cancer. :: 04-05-2007 :: Pfizer, Inc. :: La Jolla Laboratories :: 10646 Science Center Drive :: San Diego CA 92121 Novel Acting Thrombolytic (NAT) :: Treatment of peripheral arterial occlusion (PAO) :: 26-01-2001 :: Nuvelo, Inc. Inc. :: 201 Industrial Road :: Suite 310 :: San Carlos CA 94070- Nucleic acid aptamer binding to tumor cell nucleolin :: Treatment of pancreatic cancer :: 17-08-2004 :: Antisoma Research Ltd. :: Hanger Lane :: Ealing :: UNITED KINGDOMNucleic acid aptamer binding to tumor cell nucleon :: Treatment of renal cell carcinoma :: 28-07-2005 :: Antisoma Research Ltd. :: Hanger Lane :: Ealing, London :: UNITED KINGDOMNZ-1002 :: Enzyme replacement therapy in patients with all subtypes of Mucopolysaccharidosis I. :: Enzyme replacement therapy in patients with all subtypes of Mucopolysaccharidosis I. :: 11-04-2001 :: Novazyme Pharmaceuticals, Inc. :: 800 Research Parkway :: Suite 200 :: Oklahoma City OK 73104 Obatoclax mesylate :: Treatment of chronic lymphocytic leukemia :: 08-10-2004 :: Gemin X, Inc. :: 5 Great Valley Parkway :: Malvern PA 19355Obatoclax mesylate :: Treatment of myelodysplastic syndrome :: 06-11-2006 :: Gemin X, Inc. :: 5 Great Valley Parkway :: Malvern PA 19355Obatoclax mesylate :: Treatment of myelofibrosis :: 01-12-2006 :: Gemin X Pharmaceuticals US, Inc. :: 400 Chesterfield Pkwy. :: Suite 100 :: Malvern PA 19355 oblimersen :: Genasense :: Treatment of acute myelocytic leukemia :: 28-08-2001 :: Genta Inc. :: Two Connell Drive :: Berkeley Heights NJ 07922oblimersen :: Genasense :: Treatment of multiple myeloma :: 28-08-2001 :: Genta, Inc. :: Two Connell Drive :: Berkeley Heights NJ 07922oblimersen :: Genasense :: Treatment of chronic lymphocytic leukemia :: 28-08-2001 :: Genta, Inc, :: Two Connell Drive :: Berkeley Heights NJ 07922oblimersen :: Genasense :: Treatment of advanced malignant melanoma (Stages II,III, IV). :: 31-07-2000 :: Genta, Inc. :: Two Connell Drive :: Berkeley Heights NJ 07922ofatumumab :: Treatment of chronic lymphocytic leukemia :: 10-03-2009 :: GlaxoSmithKline :: One Franklin Plaza :: Phildelphia PA 19101oglufanide disodium :: Treatment of ovarian cancer :: 24-09-2001 :: Implicit Bioscience Pty Ltd :: P. 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Box 2072 :: Toowong Business Center :: AUSTRALIAOM 401 :: Drepanol :: Prophylactic treatment of sickle cell disease. :: 24-10-1991 :: Omex International, Inc. :: 6001 Savoy, Suite 110 :: Houston TX 77036omacetaine mepesuccinate :: Treatment of myelodysplastic syndromes :: 12-01-2009 :: ChemGenex Pharmaceuticals, Inc. :: 3715 Haven Avenue :: Menlo Park CA 94025Omacetaxine mepesuccinate :: Treatment of chronic myelogenous leukemia :: 10-03-2006 :: ChemGenex Pharmaceuticals, Inc. :: 3715 Haven Avenue :: Menlo Park CA 94025Omega-3 (n-3) polyunsaturated fatty acid with all double bonds in the cis configuration :: Prevention of organ graft rejection. :: 22-11-1995 :: Research Triangle Pharmaceuticals :: 4364 South Alston Avenue :: Durham NC 27713Omega-3 (n-3) polyunsaturated fatty acids :: Omacor :: Treatment of IgA nephropathy. :: 04-05-2000 :: Pronova Biocare, AS :: PO Box 420 :: 1327 Lysaker :: NORWAYOmegaven emulsion :: Omegaven :: Treatment of parenteral nutrition-associated liver disease :: 27-02-2008 :: Fresenius Kabi Deutschland GmbH :: Daimlerstrasse 16 :: GERMANYomigapil :: Treatment of congenital muscular dystrophy. :: 24-06-2008 :: Santhera Pharmaceuticals Limited :: Hammerstrasse 47 :: SWITZERLANDoncophage :: Treatment of glioma :: 14-04-2009 :: Antigenics, Inc. :: 3 Forbes Road :: Lexington MA 02421Oncorad Ov103 :: Treatment of ovarian cancer. :: 24-04-1990 :: Cytogen Corporation :: 600 College Road East :: Princeton NJ 08540oral unfractionated heparin :: Treatment of sickle cell disease :: 29-01-2004 :: TRF Technologies, Inc. :: 863 Mitten Road, Suite 101 :: Burlingame CA 94010Orgotein for injection :: Treatment of familial amyotrophic lateral sclerosis associated with a mutation of the gene (on chromosome 21q) for copper, zinc superoxide dismutase. :: 22-12-1994 :: Oxis International, Inc. :: 6040 N. Cutter Circle, Suite 317 :: Portland OR 97217-3935 Oxaliplatin :: Treatment of ovarian cancer. :: 06-10-1992 :: Debio Pharm S.A. :: Rue des Terreaux 17 :: CH-1000 :: SWITZERLANDOxalobacter formigenes :: Treatment of primary hyperoxaluria :: 29-03-2006 :: OxThera, Inc. :: 13709 Progress Blvd. #17 :: Alachua FL 32615Oxandrolone :: Oxandrin :: Treatment of short stature associated with Turner's syndrome. :: 05-07-1990 :: Bio-Technology General Corp. :: 70 Wood Avenue, South :: Iselin NJ 08830Oxandrolone :: Treatment of constitutional delay of growth and puberty. :: 05-10-1990 :: Bio-Technology General Corp. :: 70 Wood Avenue, South :: Iselin NJ 08830Oxandrolone :: Oxandrin :: Treatment of patients with Duchenne's muscular dystrophy and Becker's muscular dystrophy. :: 22-04-1997 :: Savient Pharmaceuticals, Inc. :: One Tower Center Boulevard, 12th floor :: East Brunswick NJ 08816Oxandrolone :: Oxandrin :: Adjunctive therapy for AIDS patients suffering from HIV-wasting syndrome. :: 06-09-1991 :: Bio-Technology General Corp. :: One Tower Center Boulevard, 12 th floor :: East Brunswick NJ 08816Oxandrolone :: Hepandrin :: Treatment of moderate/severe acute alcoholic hepatitis in the presence of moderate protein calorie malnutrition. :: 18-03-1994 :: Bio-Technology General Corp. :: 70 Wood Avenue South :: Iselin NJ 08830Oxymorphone :: Numorphan H.P. :: For relief of severe intractable pain in narcotic-tolerant patients. :: 19-03-1985 :: DuPont Merck Pharmaceutical Company :: P.O. Box 80027 :: Wilmington DE 19880Oxypurinol :: Treatment of hyperuricemia in patients intolerant to allopurinol. :: 09-11-1998 :: Cardiome Pharma Corp. :: 3650 Westbrook Mall :: Vancouver, B.C. :: CANADAp1-(uridine 5'-)-p4-(2'-deoxycytidine 5'-) tetraphosphate, tetrasodium salt :: For the treatment of cystic fibrosis :: 07-03-2001 :: Inspire Pharmaceuticals, Inc. :: 4222 Emperor Blvd. :: Suite 470 :: Durham NC 27703 P1, P4-Di(uridine 5'-tetraphosphate), tetrasodium salt :: Treatment of cystic fibrosis. :: 27-10-1998 :: Inspire Pharmaceuticals, Inc. :: 4222 Emperor Blvd., Suite 470 :: Durham NC 27703paclitaxel :: Treatment of pancreatic cancer :: 01-05-2009 :: MediGene AG :: Lochhamer Str. 11 :: GERMANYPaclitaxel :: Paxene :: Treatment of AIDS-related Kaposi's sarcoma. :: 15-04-1997 :: Baker Norton Pharmaceuticals, Inc. :: 4400 Biscayne Boulevard :: Miami FL 33137paclitaxel aqueous gel :: OncoGel ™ :: Treatment of brain cancer. :: 23-12-2008 :: Protherics, Inc. :: 5214 Maryland Way :: Suite 405 :: Brentwood TN 37027 paclitaxel aqueous gel :: OncoGel(tm) :: Treatment of esophageal cancer :: 01-02-2008 :: Protherics, Inc. :: 5214 Maryland Way :: Brentwood TN 37027paclitaxel, micellar :: Paclical :: Treatment of ovarian cancer :: Oasmia Pharmaceutical AB :: Vallongatan :: Uppsala :: SWEDENPafuramidine maleate :: Treatment of human African trypanosomiasis (sleeping sickness) :: 31-08-2007 :: Immtech Pharmaceuticals, Inc. :: 150 Fairway Drive :: Vernon Hills IL 60061Pafuramidine maleate :: Treatment of malaria :: 14-05-2007 :: Immtech Pharmaceuticsl, Inc. :: 150 Fairway Drive :: Vernon Hills IL 60061pafuramidine maleate :: Treatment of pneumocystis jiroveci pneumonia :: 17-11-2006 :: Immtech Pharmaceuticals, Inc. :: 150 Fairway Drive :: Suite 150 :: Vernon Hills IL 60061 Palifosfamide :: Treatment of soft tissue sarcomas :: 05-05-2008 :: Ziopharm Oncology, Inc. :: One First Avenue, Parris Building 34 :: Boston MA 02129Panobinostat :: Faridak :: Treatment of cutaneous T-cell lymphoma :: 26-09-2007 :: Novartis Pharmaceuticals Corporation :: One Health Plaza :: East Hanover NJ 07936-1080 Papain, trypsin, and chymotrypsin :: Wobe-Mugos :: Treatment of multiple myeloma. :: 21-12-1998 :: Marlyn Nutraceuticals, Inc. :: 14851 N. Scottsdale Rd. :: Scottsdale AZ 85254parathyroid hormone :: Treatment of hypoparathyroidism. :: 31-08-2007 :: NPS Pharmaceuticals, Inc. :: 300 Interpace Parkway :: Parsippany NJ 07054paromomycin sulfate/gentamicin sulfate :: Treatment of non-complicated Old World cutaneous leishmaniasis :: 18-01-2008 :: Office of the Surgeon General :: Department of the Army :: 1430 Veteran's Drive :: Ft. Detrick MD 21702 Parvovirus B19 (recombinant VP1 and VP2; S.frugiperda cells) vaccine :: MEDI-491 :: Prevention of transient aplastic crisis in patients with sickle cell anemia. :: 07-05-1999 :: MedImmune, Inc. :: 35 West Watkins Mill Rd. :: Gaithersburg MD 20878Patul-end :: "Treatment of patulous eustachian tube. " :: 18-02-1997 :: Ear Foundation :: 2420 Castillo Street, Suite 100 :: Santa Barbara CA 93105Patupilone :: Treatment of ovarian cancer. :: 04-10-2005 :: Novartis Pharmaceutical Corporation :: One Health Plaza :: East Hanover NJ 07936-1080 PEG-glucocerebrosidase :: Lysodase :: For use as chronic enzyme replacement therapy in patients with Gaucher's disease who are deficient in glucocerebrosidase. :: 09-12-1992 :: National Institute of Mental Health, NIH :: 49 Convent Dr. MSC4405 :: Bldg. 49, Room B1EE16 :: Bethesda MD 20892-4405Peginterferon alfa-2a :: PEGASYS :: Treatment of chronic myelogenous leukemia. :: 30-09-1999 :: Hoffman-La Roche Inc. :: 340 Kingsland St. :: Nutley NJ 07110-1199 Peginterferon alfa-2a :: PEGASYS :: Treatment of renal cell carcinoma. :: 13-07-1998 :: Hoffman-La Roche Inc. :: 340 Kingsland St. :: Nutley NJ 07110-1199 peginterferon alfa-2b :: PegIntron :: Treatment of malignant melanoma stages IIb through IV. :: 09-04-2008 :: Schering-Plough Corporation :: 2000 Galloping Hill Road :: Kenilworth NJ 07933-0530 PEG-interleukin-2 :: Treatment of primary immunodeficiencies associated with T-cell defects. :: 01-02-1990 :: Chiron Corporation :: 4560 Horton Street :: Emeryville CA 94608Pegylated arginine deiminase :: Melanocid :: Treatment of invasive malignant melanoma. :: 12-04-1999 :: Polaris Pharmaceuticals, Inc. :: A Polaris Group Company :: Suite 106 :: San Diego CA 92121 Pegylated arginine deiminase :: Hepacid :: Treatment of hepatocellular carcinoma. :: 26-03-1999 :: Polaris Pharmaceuticals, Inc. :: A Polaris Group Company :: 6370 Nancy Ridge Drive :: San Diego CA 92121 Pegylated recombinant human megakaryocyte growth and development factor :: MEGAGEN :: For reducing the period of thrombocytopenia in patients undergoing hematopoietic stem cell transplantation. :: 20-10-1997 :: Amgen, Inc. :: One Amgen Center Dr. :: Thousand Oaks CA 91320-1789 Peldesine :: Treatment of cutaneous T-cell lymphoma. :: 05-10-1993 :: BioCryst Pharmaceuticals, Inc. :: 2190 Parkway Lake Drive :: Birmingham AL 35244Pentamidine isethionate :: Treatment of Pneumocystis carinii pneumonia. :: 29-10-1984 :: Aventis Behring L.L.C. :: 1020 First Avenue :: PO Box 61501 :: King of Prussia PA 19406-0901Pentamidine isethionate (inhalation) :: Pneumopent :: Prevention of Pneumocystis carinii pneumonia in patients at high risk of developing this disease. :: 05-10-1987 :: Fisons Corporation :: 755 Jefferson Rd., P.O. Box 1710 :: Rochester NY 14603pentetate trisodium :: diethylenetriaminepentaacetate :: Treatment of patients with known or suspected internal contamination with plutonium, americium, or curium. :: 12-04-2004 :: Heyl Chemisch-Pharmazeutische Fabrik GMBH & Co. KG :: Goerzallee 253 :: Fedderal of Republic of Germany :: GERMANYpentosan polysulfate sodium :: Treatment of sickle cell disease. :: 21-11-2008 :: TRF Pharma, Inc. :: 863 Mitten Road :: Burlingame CA 94010Pentostatin :: Nipent :: Treatment of patients with chronic lymphocytic leukemia. :: 29-01-1991 :: SuperGen, Inc. :: 4140 Dublin Blvd. :: Suite 200 :: Dublin CA 94568 Pentostatin :: Nipent :: Treatment of peripheral T-cell lymphomas. :: 24-11-1999 :: SuperGen, Inc. :: 4140 Dublin Blvd. :: Suite 200 :: Dublin CA 94568 Pentostatin :: Nipent :: Treatment of cutaneous T-cell lymphoma. :: 27-03-1998 :: SuperGen, Inc. :: 4140 Dublin Blvd. :: Suite 200 :: Dublin CA 94568 Peptide 144 TGF beta-1 inhibitor :: Treatment of systemic sclerosis :: 27-04-2006 :: Digna Biotech, S.L. :: Avenida Carlos III el Noble :: Pamplona (Navarra) :: SPAINPeptide 144 TGF beta-1-inhibitor :: Treatment of localized scleroderma :: 26-04-2006 :: Digna Biotech, S.L. :: Avenida Carlos III el Noble, 36, 1 Dcha. 31003 :: SPAINPeptidomimetic analog of hexarelin :: Diagnosis of growth hormone deficiency :: 14-05-2007 :: Ardana Bioscience Ltd. :: 38 Melville Street :: Scotland :: UNITED KINGDOMPerflubron :: LiquiVent :: Treatment of acute respiratory distress disease (ARDS) in adults :: 26-04-2001 :: Alliance Pharmaceutical Corp. :: 3040 Science Park Road :: San Diego CA 92191Perfosfamide :: Pergamid :: For use in the ex-vivo treatment of autologous bone marrow and subsequent reinfusion in patients with acute myelogenous leukemia, also referred to as acute nonlymphocytic leukemia. :: 04-12-1989 :: Scios Nova, Inc. :: 2450 Bayshore Parkway :: Mountain View CA 94043Pergolide :: Permax :: Treatment of Tourette's syndrome. :: 20-11-1997 :: Sallee, Floyd R. M.D., Ph.D. :: Cincinnati Children's Hospital Medical Center :: 3333 Burnet Ave. :: Cincinnati OH 45229-3039Phenylacetate :: For use as an adjunct to surgery, radiation therapy and chemotherapy for the treatment of patients with primary or recurrent malignant glioma. :: 06-03-1998 :: Elan Drug Delivery, Inc. :: 1300 Gould Dr. :: Gainesville GA 30504Phenylalanine ammonia-lyase :: Phenylase :: Treatment of hyperphenylalaninemia. :: 08-03-1995 :: Biomarin Pharmaceutical :: 105 Digital Drive :: Novato CA 94949Phenylbutyrate :: Treatment of acute promyelocytic leukemia. :: 19-01-2000 :: Elan Drug Delivery, Inc. :: 1300 Gould Dr. :: Gainesville GA 30504phenylephrine :: Treatment of ileal pouch anal anastomosis related fecal incontinence :: 14-02-2002 :: S.L.A. Pharma :: Unit 3, Hill Farm Industrial Estate :: Leavesden, Watford :: UNITED KINGDOMPhosphocysteamine :: Treatment of cystinosis. :: 12-09-1988 :: Medea Research Laboratories :: Port Jefferson Business Center :: 200 Wilson Street, Building D-6 :: Port Jefferson NY 11776 phosphorothioate antisense olignucleotide against EWS-Fli-1 :: Treatment of Ewing's sarcoma :: 22-09-2008 :: The Cure Our Children Foundation :: 1730 Michael Lane :: Pacific Palisades CA 90272-2037 phosphorothioate oligonucleotide :: Treatment of amyotrophic lateral sclerosis :: 09-11-2007 :: Isis Pharmaceuticals, Inc. :: 1896 Rutherford Road :: Carlsbad CA 92008Picoplatin :: Treatment of small cell lung cancer :: 02-11-2005 :: Poniard Pharmaceuticals :: 300 Elliott Avenue West :: Seattle WA 98119Piracetam :: Nootropil :: Treatment of myoclonus. :: 02-10-1987 :: UCB Pharma, Inc. :: 1950 Lake Park Drive :: Smyrna GA 30080Piritrexim isethionate :: Treatment of infections caused by Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium-intracellulare. :: 13-06-1988 :: Burroughs Wellcome Company :: 3030 Cornwallis Road :: P.O. Box 12700 :: Research Triangle Park NC 27709 Plasmid DNA vector expressing cystic fibrosis transmembrane gene :: Treatment of cystic fibrosis :: 29-03-2005 :: Copernicus Therapeutics, Inc. :: 11000 Cedar Avenue :: Cleveland OH 44106plasmin (human) :: Treatment of acute peripheral arterial occlusion (aPAO) :: 30-03-2009 :: Talecris Biotherapeutics, Inc. :: 8368 US 70 West :: Clayton NC 27520Plevitrexed :: Plevitrexed :: Treatment of ovarian cancer :: 14-05-2007 :: BTG International, Ltd :: 10 Fleet Place :: London EC4M 7SB :: UNITED KINGDOMPlevitrexed :: Plevitrexed :: Treatment of gastric (stomach) cancer :: 29-05-2007 :: BTG International Ltd :: 10 Fleet Place :: London EC4M 7SB :: UNITED KINGDOMPlitidepsin :: Aplidin :: Treatment of acute lymphoblastic leukemia :: 18-06-2004 :: PharmaMar USA, Inc :: University Park at M.I.T. :: The Richards Building 64 :: Cambridge MA 02139-4170Plitidepsin :: Aplidin :: Treatment of multiple myeloma :: 30-09-2004 :: PharmaMar USA, Inc. :: University Park at M.I.T. :: The Rishards Building :: Cambridge MA 02139-4170Poloxamer 188 :: Treatment of vasospasm in subarachnoid hemorrhage patients following surgical repair of a ruptured cerebral aneurysm. :: 05-08-1997 :: CytRx Corporation :: 154 Technology Parkway :: Norcross GA 30092Poloxamer 188 :: Flocor :: Treatment of sickle cell crisis. :: 27-06-1989 :: SynthRx Corporation :: 4606 Willow :: Bellaire TX 77401Poloxamer 188 :: Florcor :: Treatment of severe burns requiring hospitalization. :: 22-02-1990 :: CytRx Corporation :: 154 Technology Parkway :: Norcross GA 30092Poloxamer 331 :: Protox :: Initial therapy of toxoplasmosis in patients with AIDS. :: 21-03-1991 :: CytRx Corporation :: 154 Technology Parkway :: Norcross GA 30092Poly I: poly C12U :: Ampligen :: Treatment of renal cell carcinoma. :: 20-05-1991 :: Hemispherx Biopharma, Inc. :: One Penn Center :: 1617 JFK Boulevard :: Philadelphia PA 19103 Poly I: poly C12U :: Ampligen :: Treatment of invasive metastatic melanoma (stage IIb, III, IV). :: 09-12-1993 :: Hemispherx Biopharma, Inc. :: One Penn Center :: 1617 JFK Boulevard :: Philadelphia PA 19103 Poly I: poly C12U :: Ampligen :: Treatment of chronic fatigue syndrome. :: 09-12-1993 :: Hemispherx Biopharma, Inc. :: One Penn Center :: 1617 JFK Boulevard :: Philadelphia PA 19103 Poly I: poly C12U :: Ampligen :: Treatment of AIDS. :: 19-07-1988 :: Hemispherx Biopharma, Inc. :: One Penn Center :: 1617 JFK Boulevard :: Philadelphia PA 19103 Polyethylene glycol (PEG)-uricase :: To control the clinical consequences of hyperuricemia in patients with severe gout in whom conventional therapy is contraindicated or has been ineffective. :: 21-02-2001 :: Savient Pharmaceuticals, Inc. :: One Tower Center Boulevard, 14th floor :: East Brunswick NJ 08816Polyethylene glycol-modified uricase :: Treatment of hyperuricemia in patients with gout refractory to conventional therapy or in whom conventional therapy is contraindicated :: 06-06-2005 :: EnzymeRx, LLC :: 17 Arcadian Avenue :: Suite 104 :: Paramus NJ 07652 Polyethylene glycol-modified uricase :: Zurase :: Prophylaxis of hyperuricemia in cancer patients prone to develop tumor lysis syndrome during chemotherapy. :: 14-09-1999 :: EnzymeRx, LLC :: 17 Arcadian Avenue :: Suite 104 :: Paramus NJ 07652 Polyethylene glycol-modified uricase :: Zurase :: Treatment of tumor lysis syndrome in cancer patients undergoing chemotherapy. :: 21-12-1998 :: EnzymeRx, LLC :: 17 Arcadian Avenue :: Suite 104 :: Paramus NJ 07652 Poly-ICLC :: Hiltonol :: Treatment of primary brain tumors. :: 17-03-1997 :: Oncovir :: 3202 Cleveland Avenue N.W. :: Washington DC 20008polyinosinic-polycytidilic acid :: Poly-ICLC :: Treatment of flavivirus infections including those due to West Nile, Japanese encephalitis, dengue, St. Louis encephalitis, yellow fever, Murray valley, and Banzai viruses :: 03-03-2003 :: Oncovir :: 3203 Cleveland Ave., NW :: Washington DC 20008-3450 polyinosinic-polycytidilic acid :: Poly-ICLC :: As an adjuvant to smallpox vaccination :: 02-08-2002 :: Oncovir :: 3203 Cleveland Ave., NW :: Washington DC 20008-3450 polyinosinic-polycytidilic acid (Poly-ICLC) :: Hiltonol :: Treatment for orthopox virus infections :: 19-11-2002 :: Oncovir :: 3203 Cleveland Ave., NW :: Washington DC 20008-3450 Polymeric oxygen :: Treatment of sickle cell anemia. :: 25-03-1992 :: Capmed USA :: P.O. Box 14 :: Bryn Mawr PA 19010polyphenon E :: Treatment of chronic lymphocytic leukemia :: 17-07-2008 :: Polyphenon E International, Inc. :: 655 Third Avenue :: New York NY 10017Polyvalent, shed-antigen melanoma vaccine :: Treatment of stage IIb to stage IV melanoma :: 09-06-2006 :: Polynoma LLC :: 11622 El Camino Real #100 :: San Diego CA 92130Porcine fetal neural dopaminergic cells and/or precursors aseptically prepared and coated with anti-MHC-1 Ab for intracerebral implantation :: NeuroCell-PD :: Treatment of Hoehn and Yahr stage 4 and 5 Parkinson's disease. :: 17-12-1996 :: Diacrin/Genzyme LLC :: One Kendall Square :: Cambridge MA 02139-1562 Porcine fetal neural dopaminergic cells and/or precursors aseptically prepared for intracerebral implantation. :: NeuroCell-PD :: Treatment of Hoehn and Yahr stage 4 and 5 Parkinson's disease. :: 17-12-1996 :: Diacrin/Genzyme LLC :: One Kendall Square :: Cambridge MA 02139-1562 Porcine fetal neural gabaergic cells and/or precursors aseptically prepared and coated with anti-MHC-1 Ab for intracerebral implantation :: NeuroCell-HD :: Treatment of Huntington's disease. :: 10-12-1996 :: Diacrin/Genzyme LLC :: One Kendall Square :: Cambridge MA 02129-1562 Porcine fetal neural gabaergic cells and/or precursors aseptically prepared for intracerebral implantation for Huntington's disease. :: NeuroCell-HD :: Treatment of Huntington's disease. :: 10-12-1996 :: Diacrin/Genzyme LLC :: One Kendall Square :: Cambridge MA 02139-1562 Porcine Sertoli cells aseptically prepared for intracerebral co-implantation with fetal neural tissue :: N-Graft :: Treatment of Hoehn and Yahr stage four and five Parkinson's disease. :: 24-06-1997 :: Titan Pharmaceuticals, Inc. :: Post Office Plaza :: 50 Division Street, Suite 503 :: Somerville NJ 08876 Porfimer sodium :: Photofrin :: Treatment of cholangiocarcinoma :: 18-11-2004 :: Axcan Scandipharm Inc. :: 22 Inverness Parkway :: Birmingham AL 35242Porfimer sodium :: Photofrin :: For the photodynamic therapy of patients with transitional cell carcinoma in situ of the urinary bladder. :: 15-11-1989 :: QLT Phototherapeutics, Inc. :: Lederle Laboratories :: 401 North Middletown Road :: Pearl River NY 10965 Porfiromycin :: Promycin :: Treatment of cervical cancer. :: 13-03-1997 :: Boehringer Ingelheim Pharmaceuticals, Inc. :: 900 Ridgebury Road :: PO Box 368 :: Ridgefield CT 06877 Porfiromycin :: Promycin :: Treatment of head and neck cancer. :: 19-09-1995 :: Boehringer Ingelheim Pharmaceuticals, Inc. :: 900 Ridgebury Road :: PO Box 368 :: Ridgefield CT 06877 Posaconazole :: Posoril :: Treatment of zygomycosis :: 16-07-2004 :: Schering-Plough Corporation :: 2000 Galloping Hill Road :: Kenilwortoh NJ 07033Potassium citrate and citric acid :: For the dissolution and control of uric acid and cysteine calculi in the urinary tract. :: 14-02-1986 :: Willen Drug Company potassium sodium aluminosilicate :: For treatment of poisoning by or exposure to cesium. :: 08-01-2007 :: Framework Therapeutics, LLC :: 1564 33rd Street, NW :: Washington DC 20007PR1 Vaccine :: Treatment of myelodysplastic syndromes requiring therapy :: 03-09-2004 :: The Vaccine Company :: P. O. Box 93921 :: Carmel CA 93921PR1 Vaccine :: Treatment of acute myelogenous leukemia :: 03-09-2004 :: The Vaccine Company :: P. O. Box 93921 :: Carmel CA 93921PR1 Vaccine :: Treatment of chronic myelogenous leukemia. :: 03-09-2004 :: The Vaccine Company :: P. O. Box 93921 :: Carmel CA 93921Pr-122 (redox-phenytoin) :: For the emergency rescue treatment of status epilepticus, grand mal type. :: 05-07-1990 :: Pharmos :: 2 Innovation Drive :: Alachua FL 32615PR-225 (redox-acyclovir) :: Treatment of herpes simplex encephalitis in individuals afflicted with AIDS. :: 29-05-1990 :: Pharmos :: 2 Innovation Drive :: Alachua FL 32615PR-239 (redox penicillin G) :: Treatment of AIDS associated neurosyphilis. :: 23-05-1990 :: Pharmos :: 2 Innovation Drive :: Alachua FL 32615Pr-320 (molecusol-carbamazepine) :: For the emergency rescue treatment of status epilepticus, grand mal type. :: 20-07-1990 :: Pharmos :: 2 Innovation Drive :: Alachua FL 32615pralatrexate :: Treatment of diffuse large B-cell lymphoma :: 20-10-2008 :: Allos Therapeutics, Inc. :: 11080 CirclePoint Road :: Westminster CO 80020pralatrexate :: Treatment of follicular lymphoma :: 20-10-2008 :: Allos Therapeutics, Inc. :: 11080 Circle Point Road, Suite 200 :: Westminister CO 80020pralatrexate :: Treatment of T-cell lymphoma :: 20-07-2006 :: Allos Therapeutics, Inc. :: 11080 CirclePoint Road :: Suite 200 :: Westminster CO 80020 pramipexole :: Mirapex :: Treatment of Tourette's syndrome in pediatric patients :: 31-01-2008 :: Boehringer-Ingelheim Pharmaceuticals, Inc. :: 900 Ridgebury Road :: Ridgefield CT 06877Pramiracetam Sulfate :: For the management of cognitive dysfunction and enhancement of antidepressant activity associated with electroconvulsive therapy. :: 04-11-1991 :: Cambridge Neuroscience, Inc. :: 1 Kendall Square, Bldg. 700 :: Cambridge MA 02139Praziquantel :: Treatment of neurocysticercosis. :: 18-04-1988 :: EM Pharmaceuticals, Inc. Prednimustine :: Sterecyt :: Treatment of malignant non-Hodgkin's lymphomas. :: 17-06-1985 :: Pharmacia Inc. :: P.O. Box 16529 :: Columbus OH 43216-6529 Primaquine phosphate :: For use in combination with clindamycin hydrochloride in the treatment of Pneumocystis carinii pneumonia associated with AIDS. :: 23-07-1993 :: Sanofi Winthrop, Inc. :: 90 Park Avenue :: New York NY 10016Procarbazine HCl :: Matulane :: Treatment of malignant glioma :: 08-08-2006 :: Sigma-Tau Pharmaceuticals, Inc. :: 9841 Washingtonian Blvd :: Suite 500 :: Gaithersburg MD 20878 Progesterone :: Establishment and maintenance of pregnancy in women undergoing in vitro fertilization or embryo transfer procedures. :: 22-12-1994 :: Watson Laboratories, Inc. :: 311 Bonnie Circle :: Corona CA 91720Propamidine isethionate 0.1% ophthalmic solution :: Brolene :: Treatment of acanthamoeba keratitis. :: 10-03-1988 :: Bausch & Lomb :: Pharmaceuticals Division :: 8500 Hidden River Parkway :: Tampa FL 33637 propanolol :: Treatment of proliferating infantile hemangiomas requiring systemic therapy :: 05-09-2008 :: Pierre Fabre Dermatologie :: Les-Cauquillous :: FRANCEProstaglandin E1 enol ester (AS-013) :: Circulase :: Treatment of Fontaine Stage IV chronic critical limb ischemia. :: 12-06-1998 :: LTT Baio-Pharma Co., Ltd :: Research & Development Division :: 2-5-1 Atago, Minato-ku, Tokyo :: JAPANProstaglandin E1 in lipid emulsion :: Lipo-PGE1 :: Treatment of ischemic ulceration of the lower limbs due to peripheral arterial disease. :: 10-09-1996 :: Alpha Therapeutic Corporation :: 5555 Valley Boulevard :: Los Angeles CA 90032Protaxel :: Treatment of ovarian cancer :: 21-05-2003 :: Biophysica, Inc. :: 2159 Avenida de la Playa :: Suite B :: La Jolla CA 92037 Protein C concentrate :: Protein C Concentrate (human) Vapor Heated, Immuno :: For use in the prevention and treatment of purpura fulminans in meningococcemia. :: 22-04-1993 :: Immuno Clinical Research Corp. :: 750 Lexington Avenue, 19th Floor :: New York NY 10022Protein C concentrate :: Protein C Concentrate (human) Vapor Heated, Immuno :: For replacement therapy in patients with congenital or acquired protein C deficiency for the prevention and treatment of warfarin-induced skin necrosis during oral anticoagulation. :: 19-06-1992 :: Immuno Clinical Research Corp. :: 750 Lexington Avenue, 19th Floor :: New York NY 10022Protirelin :: Prevention of infant respiratory distress syndrome associated with prematurity. :: 24-08-1993 :: UCB Pharma, Inc. :: 1950 Lake Park Drive :: Smyrna GA 30080Protirelin injection :: Treatment of amyothrophic lateral sclerosis. :: 10-01-1985 :: Abbott Laboratories :: 200 Abbott Park Road :: Abbott Park IL Pulmonary surfactant replacement :: Prevention and treatment of infant respiratory distress syndrome. :: 05-12-1988 :: Scios Nova, Inc. :: 2450 Bayshore Parkway :: Mountain View CA 94043purified bovine type collagen :: Treatment of idiopathic pulmonary fibrosis :: 27-04-2009 :: ImmuneWorks, Inc. :: 351 West 10th Street :: Indianapolis IN 46202Purified extract of Pseudomonas aeruginosa :: ImmuDyn :: Treatment of immune thrombocytopenia purpura where it is required to increase platelet counts. :: 22-09-1997 :: Able Laboratories, Inc. :: 200 Highland Avenue :: Suite 30 :: Needham MA 02494 Purified type II collagen :: Colloral :: Treatment of juvenile rheumatoid arthritis. :: 09-02-1995 :: AutoImmune, Inc. :: 128 Spring Street :: Lexington MA 02421Pyruvate :: Treatment of interstitial lung disease. :: 21-02-2001 :: Cellular Sciences, Inc :: 84 park Avenue :: P.O. Box 968 :: Flemington NJ 08822 Quinacrine hydrochloride :: For prevention of recurrence of pneumothorax in patients at high risk of recurrence. :: 17-10-1984 :: Lyphomed, Inc. quinine sulfate :: Treatment of malaria excluding Plasmodium faliparum :: 02-12-2008 :: Zydus Pharmaceuticals, Inc. :: 210 Carnegie Center :: Princeton NJ 08540R-(-)-gossypol :: Treatment of chronic lymphocytic leukemia. :: 24-10-2006 :: Ascenta Therapeutics, Inc. :: 101 Lindenwood Drive :: Suite 405 :: Malvern PA 19355 R-4-amino-3-(4-chlorophenyl)butanoic acid :: Treatment of the behavorial abnormalities associated with fragile X syndrome. :: 28-11-2008 :: Seaside Therapeutics, Inc. :: 840 Memorial Drive :: Cambridge MA 02139rAAV2-CB-hRPE65 :: Treatment of type II Leber's Congential Amaurosis :: 11-02-2005 :: Applied Genetic Technologies Corp. :: 11801 Research Drive :: Suite D :: Alachua FL 32615 Rabbit anti-human thymocyte globulin (rATG) :: Thymoglobulin :: Induction treatment to prevent rejection and to minimize maintenance immunosupression in pediatric liver transplant recipients :: 26-09-2006 :: Children's Hospital of Pittsburgh :: University of Pittsburgh :: Pittsburgh PA 15213ranprinase :: Onconase :: Treatment of malignant mesothelioma :: 25-01-2007 :: Alfacell Corporation :: 225 Belleville Ave. :: Bloomfield NJ 07003Rapamycin :: Treatment of tuberous sclerosis complex :: 20-03-2007 :: OncoImmune, Inc. :: 4532 Benderton Court :: Columbus OH 43220Rapamycin (mTOR) inhibitor :: Treatment of bone sarcoma :: 09-08-2005 :: ARIAD Pharmaceuticals, Incx. :: 26 Landsdowne Street :: Cambridge MA 02139-4234 raxibacumab :: Abthrax :: Treatment of anthrax :: 12-11-2003 :: Human Genome Sciences, Inc. :: 14200 Shady Grove Road :: Rockville MD 20850recombinant adeno-associated virus alpha 1-antitrypsin vector :: rAAV-AAT :: Treatment of alpha1-antitrypsin deficiency :: 27-01-2003 :: Applied Genetic Technologies Corp. :: 12085 Research Drive :: Suite 110 :: Alachua FL 32615 Recombinant anti-CD22 immunotoxin :: Treatment of CD22-positive chronic lymphocytic leukemia :: 15-11-2007 :: MedImmune, LLC :: One MedImmune Way :: Gaithersburg MD 20878Recombinant anti-CD22 immunotoxin :: Treatment of hairy cell leukemia :: 15-11-2007 :: MedImmune, LLC :: One MedImmune Way :: Gaithersburg MD 20878Recombinant anti-CD40 monoclonal antibody :: Treatment of chronic lymphocytic leukemia :: 12-08-2005 :: Novartis Pharmaceutical Corporation :: Oncology Business Unit :: One Health Plaza :: East Hanover NJ 07986 Recombinant anti-CD-40 monoclonal antibody :: Treatment of multiple myeloma :: 25-01-2006 :: Novartis Pharmaceutical Corporation :: Oncology Business Unit :: One Health Plaza :: East Hanover NJ 07936 Recombinant bactericidal/permeability-increasing protein :: Neuprex :: Treatment of severe meningococcal disease. :: 22-06-1998 :: Xoma (US) LLC :: 2910 Seventh Street :: Berkeley CA 94710recombinant chimeric monoclonal antibody to anthrax :: Anthim :: Treatment of exposure to B. anthracis spores :: 09-06-2006 :: Elusys Therapeutics, Inc. :: 25 Riverside Drive :: P.O. Box 102 :: Pine Brook NJ 07058 Recombinant coagulation factor VIIa :: Novoseven :: Treatment of diffuse alveolar hemorrhage :: 26-04-2006 :: PharmaOrigin ApS :: Scion DTU :: Boge alle 5, 1.tv :: DENMARKRecombinant deriative of C3 transferase :: Cethrin :: Treatment of acute spinal cord injury :: 18-11-2005 :: Alseres Pharmaceuticals, Inc. :: 85 Main Street :: Hopkinton MA 01748Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs :: Treatment of thrombotic thrombocytopenic purpura including its congential, acquired idiopathic, and secondary forms. :: 29-07-2008 :: Baxter Healthcare Corporation :: Baxter Bioscience :: Westlake Village CA 91362Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs :: Prevention of thrombotic thrombocytopenic purpura including its congential, acquired idiopathic and secondary forms. :: 29-07-2008 :: Baxter Healthcare Corporation :: Baxter Bioscience :: Westlake Village CA 91362Recombinant Epstein-Barr virus gp350 glycoprotein vaccine :: Prevention of post-transplantation lymphoproliferative disorders in pediatric recipients of solid-organ transplantation :: 18-08-2005 :: Henogen S.A. :: Rue des Professeurs Jenner et Brachet, 12 :: B-6041-Gosselies :: BELGIUMRecombinant fully human monoclonal antibody to anthrax protective antigen :: Valortim :: Treatment of anthrax infection :: 16-02-2006 :: PharmAthene, Inc. :: One Park Place :: Suite 450 :: Annapolis MD 21401 recombinant fusion protein with a truncated form of the cytotoxic protein Pseudomonas exotoxin :: Proxinium :: "Treatment of Ep-CAM-positive squamous cell carcinoma of the head and neck" :: 28-01-2005 :: Viventia Biotech, Inc. :: 10 Four Seasons Place :: Toronto ON M9B 6H7 :: CANADARecombinant glycine2-human glucagon-like peptide-2 :: Treatment of short bowel syndrome. :: 29-06-2000 :: NPS Allelix Corp. :: 6850 Goreway Dr. :: Ontario L4V 1V7 :: CANADARecombinant human alpha 1-antitrypsin :: Prevention of bronchopulmonary dysplasia :: 28-04-2005 :: Arriva Pharmaceuticals, Inc. :: 1010 Atlantic Avenue :: Alameda CA 94501recombinant human alpha 1-antitrypsin (rAAT) :: Treatment of cystic fibrosis :: 20-11-2001 :: Arriva Pharmaceuticals, Inc. :: 2020 Challenger Drive :: Alameda CA 94501recombinant human alpha-1 antitrypsin :: Treatment of cystic fibrosis. :: 06-03-1998 :: PPL Therapeutics (Scotland) Limited :: Roslin, Edinburgh :: EH259PP Scotland :: UNITED KINGDOMrecombinant human alpha-1 antitrypsin (rAAT) :: To delay progression of chronic obstructive pulmonary disease resulting from AAT deficiency-mediated emphysema and bronchiectasis :: 28-08-2001 :: Arriva Pharmaceuticals, Inc. :: 1010 Atlantic Avenue :: Alameda CA 94501Recombinant Human Alpha-Fetoprotein (rhAFP) :: Treatment of myasthenia gravis :: 22-02-2001 :: Merrimack Pharmaceuticals, Inc. :: 101 Binney Street :: Cambridge MA 02142Recombinant human alpha-mannosidase :: Treatment of alpha-mannosidosis :: 02-02-2006 :: Zymenex A/S :: Roskildevej 12 C :: DENMARKRecombinant human anti-GDF-8 (growth and differentiation factor-8) antibody :: Treatment of Duchenne and Becker muscular dystrophies :: 16-02-2005 :: Wyeth Pharmaceuticals, Inc. :: P. O. Box 8299 :: Philadelphia PA 19101-8299 Recombinant human antithrombin III :: Treatment of antithrombin III dependent heparin resistance requiring anticoagulation. :: 06-04-2000 :: AT III LLC :: c/o Genzyme Corporation :: 15 Pleasant St. Connector, P.O. Box 9322 :: Framingham MA 01701 recombinant human arylsulphatase A :: Treatment of metachromatic leukodystrophy (MLD). :: 11-04-2008 :: Shire Human Genetic Therapies :: 700 Main Street :: Cambridge MA 02139Recombinant human C1 inhibitor :: Treatment of capillary leakage syndrome :: 09-06-2006 :: Pharming Technologies B.V. :: Archimedesweg 4 :: NETHERLANDSRecombinant human C1 inhibitor :: Prevention and/or treatment of delayed graft function after solid organ transplantation :: 09-06-2006 :: Pharming Technologies B.V. :: Archimedesweg 4 :: NETHERLANDSRecombinant human C1-esterase inhibitor :: Treatment of (acute attacks of) angioedema caused by hereditary or acquired C1-esterase inhibitor deficiency. :: 23-02-1999 :: Pharming N.V. :: Cipalstreet 3 :: B-2440 Geel :: BELGIUMRecombinant human C1-esterase inhibitor :: Prophylactic treatment of angioedema caused by hereditary or acquired C1-esterase inhibitor deficiency. :: 23-02-1999 :: Pharming N.V. :: Cipalstreet 3 :: B-2440 Geel :: BELGIUMRecombinant human CD4 immunoglobulin G :: Treatment of AIDS resulting from infection with HIV-1. :: 30-08-1990 :: Genentech, Inc. :: 460 Point San Bruno Boulevard :: South San Francisco CA 94080Recombinant human Clara Cell 10kDa protein :: Prevention of neonatal bronchopulmonary dysplasia in premature neonates with respiratory distress syndrome. :: 13-07-1998 :: CC10 Sweden AB :: Kornhamnstorg 53 :: Box 2077 :: SWEDENrecombinant human coagulation factor IX fusion protein :: For the control and prevention of hemorrhagic episodes in patients with hemophilia B (congential factor IX deficiency or Christmas disease). :: 30-10-2008 :: Syntonix Pharmaceuticals :: A Subsidiary of Biogen Idec :: Waltham MA 02451Recombinant human endostatin protein :: Treatment of neuroendocrine tumors :: 13-08-2001 :: EntreMed, Inc. :: 9640 Medical Center Drive :: Rockville MD 20850recombinant human endostatin protein :: Treatment of metastatic melanoma :: 21-02-2002 :: EntreMed, Inc. :: 9640 Medical Center Drive :: Rockville MD 20850Recombinant human fibrinogen :: Treatment of bleeding in patients deficient in fibrinogen :: 04-10-2007 :: Pharming Technologies B.V. :: Archimedesweg 4 :: NETHERLANDSrecombinant human fibroblast growth factor-20 :: Treatment of radiation induced oral mucositis :: 29-01-2004 :: CuraGen Corporation :: 322 East Main Street :: Branford CT 06405Recombinant human gelsolin :: Treatment of acute and chronic respiratory symptoms of bronchiectasis. :: 06-03-1995 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Recombinant human gelsolin :: Treatment of the respiratory symptoms of cystic fibrosis. :: 12-01-1994 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02124Recombinant human granulocyte colony stimulating factor :: Prevention of implantation failure :: 24-07-2006 :: Nora Therapeutics, Inc. :: 2400 Boston Street :: Baltimore MD 21224Recombinant human highly phosphorylated acid alpha-glucosidase :: TBD :: For enzyme replacement therapy in patients with all subtypes of glycogen storage disease type II (GSDII, Pompe Disease) :: 20-09-2000 :: Novazyme Pharmaceuticals, Inc. :: 800 Research Parkway :: Suite 200 :: Oklahoma City OK 73104 recombinant human histone H1.3; recombinant human N-bis-met-histone H1.3 :: Oncohist (r) :: Treatment of acute myeloid leukemia :: 20-10-2008 :: SymbioTec GmbH :: Sciene Park Saar 1 :: Saarbruecken :: GERMANYRecombinant human insulin-like growth factor 1 :: IGF-1 :: Treatment of growth hormone receptor deficiency. :: 07-06-1995 :: Pharmacia & Upjohn :: 7000 Portage Road :: Kalamazoo MI 49001-0199 Recombinant human insulin-like growth factor 1 :: IGF-1 :: Treatment of antibody-mediated growth hormone resistance in patients with isolated growth hormone deficiency Ia. :: 07-06-1995 :: Pharmacia & Upjohn :: 7000 Portage Road :: Kalamazoo MI 49001-0199 Recombinant human insulin-like growth factor-I :: PV802 :: Treatment of short-bowel syndrome as a result of resection of the small bowel or as a result of congenital dysfunction of the intestines. :: 16-02-2000 :: GroPep Pty Ltd. :: Gate 11, Victoria Dr. :: Adelaide SA 5000 :: AUSTRALIARecombinant human insulin-like growth factor-I :: Treatment of post-poliomyelitis syndrome. :: 13-10-1995 :: Cephalon, Inc. :: 41 Moores Road :: P. O. Box 4011 :: Frazer PA 19355 Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3 :: Treatment of major burns that require hospitalization. :: 15-06-1999 :: Insmed, Inc. :: 8720 Stony Point Parkway :: Suite 200 :: Glen Allen VA 23235-Recombinant human interleukin-12 :: Treatment of renal cell carcinoma. :: 20-10-1997 :: Genetics Institute, Inc. :: 87 CambridgePark Drive :: Cambridge MA 02140Recombinant Human Interleukin-21 (rIL-21) :: Treatment of stage II (T4), III or IV malignant melanoma. :: 04-10-2005 :: Zymo Genetics, Inc :: 1201 Eastlake Avenue East :: Seattle WA 98102Recombinant human keratinocyte growth factor :: Reducing the incidence and severity of radiation-induced xerostomia. :: 20-12-1999 :: Amgen Inc. :: One Amgen Center Dr. :: Thousand Oaks CA 91320-1799 Recombinant human lysosomal acid lipase or cholesteryl ester hydrolase :: Cholestrase :: Treatment of lipase deficiencies, including Wolman Disease and cholesteryl ester storage disease :: 14-07-2005 :: Lysosomal Acid Lipase, LLC :: Subsidiary of Kentucky BioProcessing, LLC :: 3700 Airpark Drive :: Owensboro KY 42301 Recombinant human microplasmin :: Treatment of peripheral arterial occlusion :: 23-01-2006 :: ThromboGenics Ltd :: Unit 14, Bridgecourt Office Park :: Dublin :: IRELANDrecombinant human minibody against complement component C5 :: MUBODINA :: Treatment of primary membranoproliferative glomerulonephritis :: 04-02-2009 :: Adienne S.r.1. :: 24128 Bergamo :: 64/B Boseta Street :: ITALYrecombinant human minibody against complement component C5 fused with RGD-motif :: Prevention of ischemmia/reperfusion injury associated with solid organ transplantation. :: 04-02-2009 :: Adienne S.r.1. :: 24128 Bergamo, 64/B Broseta Street :: ITALYrecombinant human monoclonal antibody to hsp90 :: Mycograb :: Treatment of invasive candidiasis :: 16-09-2002 :: Novartis Pharmaceuticals Corp. :: One Health Plaza :: East Hanover NJ 07936-1080 :: UNITED KINGDOMRecombinant human nerve growth factor :: Treatment of HIV-associated sensory neuropathy. :: 16-04-1999 :: Genentech, Inc. :: 1 DNA Way :: South San Francisco CA 94080recombinant human neutrophil inhibitor (hNE) :: Treatment of cystic fibrosis :: 09-12-2003 :: Dyax Corporation :: 300 Technology Square :: Cambridge MA 02139Recombinant human platelet derived growth factor BB :: Treatment of osteonecrosis of the jaws :: 01-02-2007 :: Luitpold Pharmaceuticals, Inc. :: P. O. Box 9001 :: One Luitpold Drive :: Shirley NY 11967 recombinant human porphobilinogen deaminase :: Porphozyme :: Treatment of acute intermittent porphyria attacks :: 09-09-2002 :: Zymenex A/S :: Roskildevej 12C :: 3400 Hillerod :: DENMARKrecombinant human porphobilinogen deaminase, erythropoetic form :: Treatment of acute intermittent porphyria preventing attacks :: 11-07-2002 :: ZymenexA/S :: Roskildevej 12C :: 3400 Hillerod :: DENMARKrecombinant human proinsulin :: Treatment of retinitis pigmentosa :: 10-12-2008 :: ProRetina Therapeutics, S.L. :: Centro de Empresas de Pozuelo :: 28224 Pozuelo de Alarcon :: SPAINRecombinant human relaxin :: Treatment of progressive systemic sclerosis. :: 03-11-1995 :: Connetics Corporation :: 3400 West Bayshore Road :: Palo Alto CA 94303recombinant human rod-derived cone viability factor :: Treatment of retinitis pigmentosa :: 07-01-2008 :: Fovea Pharmaceuticals :: 12 Rue Jean Antoine de Baif :: Paris :: FRANCERecombinant human thrombopoietin :: For use in accelerating platelet recovery in patients undergoing hematopoietic stem cell transplantation. :: 29-09-1997 :: Genentech, Inc. :: 1 DNA Way :: South San Francisco CA 94080-4990 recombinant human type I pancreatic elastase :: Prevention of arteriovenous fistula maturation and arteriovenous graft failure in patients with end stage renal disease who are receiving hemodialysis or preparing for hemodialysis :: 03-04-2009 :: Proteon Therapeutics, Inc. :: 200 West Street :: Waltham MA 02451recombinant human type VII collagen :: Treatment of hereditary dystrophic epidermolysis bullosa (DEB) :: 18-06-2008 :: David T. Woodley, MD and Mei Chen, MD :: USC Department of Dermatology, Cancer Research Lab :: 1303 North Mission Road :: Los Angeles CA 90033 Recombinant humanized MAb 5c8 :: Prevention of rejection of solid organ transplants. :: 22-03-1999 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Recombinant humanized MAb 5c8 :: Prevention of rejection of pancreatic islet cell transplants. :: 22-03-1999 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Recombinant humanized MAb 5c8 :: Prevention and treatment of Factor VIII/Factor IX inhibitors in patients with hemophilia A or B. :: 14-10-1998 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Recombinant humanized monclonal antibody 5c8 :: Treatment of immune thrombocytopenic purpura. :: 03-02-1998 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Recombinant humanized monoclonal antibody 5c8 :: Treatment of systemic lupus erythematosus. :: 18-02-1998 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Recombinant methionyl brain-derived neurotrophic factor :: Treatment of amyotrophic lateral sclerosis. :: 28-11-1994 :: Amgen, Inc. :: One Amgen Center Dr. :: Thousand Oaks CA 91320-1799 recombinant ovine interferon tau :: Tauferon :: Treatment of pediatric multiple sclerosis :: 25-01-2005 :: PEPGEN Corporation :: 1301 Harbor Bay Parkway :: Alameda CA 94502Recombinant Porcine Factor VIII, B-domain Deleted :: Treatment and prevention of episodic bleeding in patients with inhibitor antibodies to human coagulation factor VIII :: 16-03-2004 :: Ipsen Limited :: 190 Bath Road :: Berkshire S11 3XE :: UNITED KINGDOMRecombinant P-Selectin glycoprotein ligand :: Prevention of delayed graft function in renal transplant patients :: 29-03-2006 :: Y's Therapeutics, Inc. :: 1111 Bayhill Drive :: Suite 405 :: San Bruno CA 94066-3002Recombinant P-selectin glycoprotein ligand-immunoglobulin Ig :: Prevention of ischemia reperfusion injury in all solid organ transplants :: 26-07-2007 :: Y's Therapeutics, Inc. :: 866 Malcolm Road :: Burlingame CA 94010Recombinant retroviral vector – glucocerebrosidase :: For use as enzyme replacement therapy for patients with types I, II, or III Gaucher disease. :: 15-11-1993 :: Genetic Therapy, Inc. :: 938 Clopper Road :: Gaithersburg MD 20878Recombinant secretory leucocyte protease inhibitor :: Treatment of cystic fibrosis. :: 29-03-1991 :: Amgen, Inc. :: 3200 Walnut Street :: Boulder CO 80301Recombinant secretory leucocyte protease inhibitor :: Treatment of congenital alpha-1 antitrypsin deficiency. :: 29-03-1991 :: Amgen Inc. :: 3200 Walnut Street :: Boulder CO 80301Recombinant soluble human CD4 :: Receptin :: Treatment of acquired immunodeficiency syndrome. :: 20-11-1989 :: Biogen, Inc. :: 14 Cambridge Center :: Cambridge MA 02142Recombinant soluble human CD4 (rCD4) :: Treatment of AIDS in patients infected with HIV virus. :: 23-03-1989 :: Genentech, Inc. :: 460 Point San Bruno Boulevard :: South San Francisco CA 94080Recombinant T-cell receptor ligand :: Treatment of multiple sclerosis patients who are both HLA-DR2 positive and autoreactive to myelin oligodendrocyte glycoprotein residues 35-55 :: 02-05-2003 :: Artielle ImmunoTherapeutics, Inc. :: 9020 SW Washington Square Road :: Suite 450 :: Tigard, OR 97223-4332Recombinant truncated SPINT2 protease inhibitor :: Treatment of cystic fibrosis :: 24-06-2005 :: Aerovance, Inc. :: 2929 Seventh Street :: Berkeley CA 94710Recombinant urate oxidase :: Prophylaxis of chemotherapy-induced hyperuricemia. :: 11-10-2000 :: Sanofi-Synthelabo Research :: 9 Great Valley Parkway :: Malvern PA 19355Reduced L-glutathione :: Cachexon :: Treatment of AIDS-associated cachexia. :: 14-02-1994 :: Telluride Pharmaceutical Corporation :: 146 Flanders Drive :: Hillsborough NJ 08876Remacemide :: Ecovia :: Treatment of Huntington's disease. :: 06-03-2000 :: AstraZeneca LP :: 725 Chesterbrook Blvd. :: Wayne PA 19087-5677 Reparixin :: Prevention of delayed graft function in solid organ transplant :: 27-01-2003 :: Dompe s.p.a. :: Via Campo di Pile :: 67100 – L'Aquila :: ITALYrepository corticotropin or adrenocorticotropic hormone :: H.P. Acthar Gel :: Treatment of infantile spasms :: 21-05-2003 :: Questcor Pharmaceuticals, Inc. :: 3260 Whipple Road :: Union City CA 94587-1217 resiniferatoxin :: Treatment of intractable pain at end-stage disease :: 13-05-2003 :: NIH/NIDCR :: Bldg 10/Rm 2N236 – DASS/CC :: 10 Convent Drive :: Bethesda MD 20892 reslizumab :: Treatment of children with eosinophilic esophagitis :: 19-12-2007 :: Ception Therapeutics, Inc. :: 101 Lindenwood Drive :: Suite 400, Valleybrook III :: Malvern PA 19335 Respiratory Syncytial Virus Immune Globulin (human) :: Hypermune RSV :: Treatment of respiratory syncytial virus lower respiratory tract infections in hospitalized infants and young children. :: 27-09-1990 :: MedImmune, Inc. :: 35 West Watkins Mill Road :: Gaithersburg MD 20878retaspimycin :: Treatment for gastrointestinal stromal tumor :: 31-08-2007 :: Infinity Pharmaceuticals, Inc. :: 780 Memorial Drive :: Cambridge MA 02139retaspimycin hydrochloride :: Treatment of melanoma stages IIb through IV. :: 24-06-2008 :: AstraZeneca Pharmaceuticals LP :: P. O. Box 8355 :: 1800 Concord Pike :: Wilmington DE 19803-8355R-etodolac :: Treatment of chronic lymphocytic leukemia :: 09-12-2002 :: Cephalon, Inc. :: 41 Moores Road :: Frazer PA 19355retroviral gamma-c cDNA containing vector :: Treatment of X linked severe combined immune deficiency disease :: 29-04-2002 :: AVAX technologies, Inc. :: 9200 Indian Creek Parkway :: Building 9, Suite 200 :: Overland Park KS 66210 Retroviral vector, R-GC and GC gene 1750 :: Treatment of Gaucher disease. :: 06-05-1997 :: Genzyme Corporation :: One Mountain Road :: P.O. Box 9322 :: Framingham MA 01701-9322Reviparin sodium :: Clivarine :: Treatment of deep vein thrombosis which may lead to pulmonary embolism in pediatric patients :: 18-06-2001 :: Abbott :: Abbott Laboratories, Dept. 389, Bldg. J-45 :: 200 Abbott Park Rd. :: Abbott Park IL 60064-6135Reviparin sodium :: Clivarine :: Long-term treatment of acute deep vein trombosis with or without pulmonary embolism in pregnant patients :: 18-06-2001 :: Abbott :: Abbott Laboratories, Dept. 389, Bldg. J-45 :: 200 Abbott Park Rd. :: Abbott Park IL 60064-6133RGG0853, E1A lipid complex :: Treatment of ovarian cancer. :: 15-09-1995 :: Targeted Genetics Corporation :: 1100 Olive Way, Suite 100 :: Seattle WA 98101rhIGF-I/rhIGFBP-3 :: SomatoKine :: Treatment of extreme insulin resistance syndromes (type A, Rabson-Mendenhall syndrome, Leprechaunism, Type B syndrome) :: 09-12-2003 :: Insmed Inc. :: 4851 Lake Brooke Drive :: Glen Allen VA 23060rh-microplasmin :: Adjunct to surgery in cases of pediatric vitrectomy :: 16-03-2004 :: ThromboGenics Inc. :: Unit 14 :: Walkinstown Avenue :: Dublin 12 :: IRELANDRibavirin :: Virazole :: Treatment of hemorrhagic fever with renal syndrome. :: 12-04-1991 :: Valeant Pharmaceuticals International :: 3300 Hyland Avenue :: Costa Mesa CA 92626Ricin (blocked) conjugated murine mca (anti-b4) :: For the ex-vivo purging of leukemic cells from the bone marrow of non-T cell acute lymphocytic leukemia patients who are in complete remission. :: 24-01-1991 :: ImmunoGen, Inc. :: 148 Sidney Street :: Cambridge MA 02139Ricin (blocked) conjugated murine MCA (anti-B4) :: Treatment of B-cell leukemia and B-cell lymphoma. :: 17-11-1988 :: ImmunoGen, Inc. :: 148 Sidney Street :: Cambridge MA 02139Ricin (blocked) conjugated murine MCA (anti-my9) :: Treatment of myeloid leukemia, including AML, and blast crisis of CML. :: 03-08-1989 :: ImmunoGen, Inc. :: 148 Sidney Street :: Cambridge MA 02139Ricin (blocked) conjugated murine MCA (anti-my9) :: For use in the ex-vivo treatment of autologous bone marrow and subsequent reinfusion in patients with acute myelogenous leukemia. :: 01-02-1990 :: ImmunoGen, Inc. :: 148 Sidney Street :: Cambridge MA 02139Ricin (blocked) conjugated murine MCA (n901) :: Treatment of small cell lung cancer :: 25-01-1991 :: ImmunoGen, Inc. :: 148 Sidney Street :: Cambridge MA 02139Ricin (blocked) conjugated murine monoclonal antibody (CD6) :: Treatment of cutaneous T-cell lymphomas, acute T-cell leukemia-lymphoma, and related mature T-cell malignancies. :: 06-09-1994 :: ImmunoGen, Inc. :: 148 Sidney Street :: Cambridge MA 02139Rifabutin :: Treatment of disseminated Mycobacterium avium complex disease. :: 18-12-1989 :: Pfizer, Inc. :: 235 East 42nd Street :: New York NY 10017Rifalazil :: Treatment of pulmonary tuberculosis. :: 13-04-1999 :: PathoGenesis Corporation :: 201 Elliott Avenue West :: Suite 150 :: Seattle WA 98119 Rifapentine :: Priftin :: Prophylactic treatment of Mycobacterium avium complex in patients with AIDS and a CD4+ count less than or equal to 75/mm3. :: 12-03-1996 :: Hoechst Marion Roussel, Inc. :: P.O. Box 9627 :: Mail Station: H3-M2516 :: Kansas City MO 64134-0627Rifapentine :: Priftin :: Treatment of Mycobacterium avium complex in patients with AIDS. :: 09-06-1995 :: Hoechst Marion Roussel , Inc. :: P.O. Box 9627 :: Mail Station: H3-M2516 :: Kansas City MO 64134-0627Rifaximin :: Normix :: Treatment of hepatic encephalopathy :: 10-02-1998 :: Salix Pharmaceuticals, Inc. :: 1700 Perimeter Park Drive :: Morrisville NC 27560RII retinamide :: Treatment of myelodysplastic syndromes. :: 06-05-1993 :: Sparta Pharmaceuticals, Inc. :: 111 Rock Road :: Horsham PA 19044-2310 Riluzole :: Rilutek :: Treatment of Huntington's disease. :: 15-10-1996 :: Rhone-Poulenc Rorer Pharmaceuticals, Inc. :: 500 Arcola Road :: PO Box 5096 :: Collegeville PA 19426-0800risedronate sodium :: Actonel :: Treatment of patients with osteogenesis imperfecta. :: 18-12-2006 :: Proctor and Gamble Pharmaceuticals :: 8700 Mason-Montgomery Road :: Mason OH 08807rituximab :: Rituxan :: Treatment of patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (Wegener's Granulomatosis, Microscopic Polyangiitis, and Churg-Strauss Syndrome) :: 14-02-2006 :: Genentech, Inc. :: 1 DNA Way :: South San Francisco CA 94080-4990 rituximab :: Rituxan :: Treatment of immune thrombocytopenic purpura :: 12-03-2002 :: Genentech, Inc. :: 1 DNA Way :: South San Francisco CA 94080-4990 rituximab :: Rituxan :: Treatment of chronic lymphocytic leukemia :: 29-01-2004 :: Genentech, Inc. :: 1DNA Way :: MS 241A :: South San Francisco CA 94080 RNA, ((2',3'-dideoxy-2',3'-imino-2',3'-seco)[dimethylamino)phosphinylideneoxy](2'a-5') (CTC CAA CAT CAA GGA AGATGG CAT TTC TAG)), P-[4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]carbonyl]-1-piperazinyl]-N,N-dimethylaminophosphonamidate :: Treatment of Duchenne Muscular Dystrophy. :: 23-10-2007 :: AVI BioPharma, Inc. :: One SW Columbia Street :: Portland OR 97258rofecoxib :: Vioxx :: Treatment of juvenile rheumatoid arthritis :: 16-03-2004 :: MERCK & Co., Inc. :: 126 East Lincoln Ave. :: Rahway NJ 07065romidepsin :: Treatment of non-Hodgkin T-cell lymphomas :: 30-09-2004 :: Gloucester Pharmaceuticals, Inc. :: One Broadway :: Cambridge MA 02142Roquinimex :: Linomide :: To prolong time to relapse in leukemia patients who have undergone autologous bone marrow transplantation. :: 01-07-1993 :: Pharmacia & Upjohn :: 7000 Portage Road :: Kalamazoo MI 49001-0199 Rose Bengal Disodium :: Treatment of metastatic melanoma :: 20-12-2006 :: Provectus Pharmaceuticals, Inc. :: 7327 Oak Ridge Highway :: Knoxville TN 37931rSP-C lung surfactant :: Venticute :: Treatment of adult respiratory distress syndrome. :: 03-04-2000 :: Byk Gulden Pharmaceuticals :: Byk-Gulden StraBe 2 :: 78467 Konstanz :: GERMANYrSP-C surfactant :: Venticute :: For use in patients with pneumonia or aspiration of gastric contents leading to intubation, mechanical ventilation, and severe oxygen impairment :: 18-09-2006 :: Altana Pharma :: 220 Park avenue :: Florham Park NJ 07932rubitecan :: Treatment of pediatric patients infected with human immunodeficiency virus and acquired immunodeficiency syndrome :: 17-07-2002 :: SuperGen, Inc. :: 4140 Dublin Blvd. :: Suite 200 :: Dublin CA 94568 S(-)-3-[3-amino-phthalimido]-glutaramide :: Treatment of multiple myeloma :: 14-03-2002 :: EntreMed Incorporated :: 9640 Medical Center Dr. :: Rockville MD 20850S-adenosylmethionine :: Treatment of AIDS-myelopathy. :: 30-04-1998 :: Genopia USA, Inc. :: 90 Gold Street, 6N :: New York NY 10038salirasib :: Treatment of panreatic cancer. :: 18-12-2006 :: Concordia Pharmaceuticals, Inc. :: 1550 Sawgrass Corporate Parkway :: Sunrise FL 33323sarsasapogenin :: Treatment of amyotrophic lateral sclerosis (ALS) :: 18-06-2004 :: Phytopharm plc :: Corpus Christi House :: Godmanchester, Cambridgeshire PE29 2HY :: UNITED KINGDOMSB-408075 :: For pancreatic cancer :: 07-12-2000 :: SmithKline Beecham Pharmaceuticals :: 1250 S. Collegeville Road :: Collegeville PA 19426-0989 SC-1 monoclonal antibody :: Treatment of patients with CD55 (sc-1) positive gastric tumors :: 12-11-2003 :: Debiovision Inc. :: 666 Sherbrooke Street West, Suite 1400 :: Montreal, Quebec :: SCH 58500 :: Treatment of primary ovarian cancer. :: 12-04-1999 :: Schering Corporation :: 2000 Galloping Hill Rd. :: Kenilworth NJ 07033SDF-1 (108) Lysine Dlmer :: Treatment of osteogenic sarcoma :: 07-07-2005 :: Chemokine Therapeutics Corporation :: 190 Agronomy Road (UBC) :: Suite 405 :: Vancouver, BC V6T 1Z3 :: CANADASecalciferol :: Osteo-D :: Treatment of familial hypophosphatemic rickets. :: 26-07-1993 :: Teva Pharmaceuticals USA :: 650 Cathill Rd. :: Sellersville PA 18960Secretory leukocyte protease inhibitor :: Treatment of bronchopulmonary dysplasia. :: 30-06-1992 :: Synergen, Inc. :: 1885 33rd Street :: Boulder CO 80301Seneca Valley virus :: Treatment of neuroendocrine tumors :: Treatment of neuroendocrine tumors :: 22-08-2008 :: Neotropix, Inc. :: 351 Phoenixville Pike :: Malvern PA 19355Sermorelin acetate :: Geref :: Adjunct to gonadotropin therapy in the induction of ovulation in women with anovulatory or oligo-ovulatory infertility who fail to ovulate in response to adequate treatment with clomiphene citrate alone and gonadotropin therapy alone. :: 13-02-1990 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370Sermorelin acetate :: Geref :: Treatment of AIDS-associated catabolism/weight loss. :: 05-12-1991 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370Serratia marcescens extract (polyribosomes) :: Imuvert :: Treatment of primary brain malignancies. :: 07-09-1988 :: Cell Technology, Inc. :: 1668 Valtec Lane :: Boulder CO 80306SGN-30 (anti-CD30 antibody) :: Treatment of CD30 positive T-cell lymphomas :: 18-02-2004 :: Seattle Genetics, Inc. :: 21823 30th Drive Southeast :: Bothell WA 98021SGN-30 (anti-CD30 mAb) :: Treatment of Hodgkin's disease :: 18-07-2003 :: Seattle Genetics, Inc :: 21823 30th Drive, Southeast :: Bothell WA 98021SGN-35 (cAC10-vcMMAE(4)) :: Treatment of anaplastic large cell lymphoma :: 23-10-2008 :: Seattle Genetics, Inc. :: 21823 30th Drive Southeast :: Bothell WA 98021SGN-40 (anti-CD40 antibody) :: Treatment of multiple myeloma. :: 13-08-2004 :: Seattle Genetics, Inc. :: 21823 30th Drive Southeast :: Bothell WA 98021Short chain fatty acid enema :: Colomed :: Treatment of chronic radiation proctitis. :: 19-08-1997 :: Richard I. Breuer, M.D. :: 1000 Central Street, Suite 615 :: Evanston IL 60201Short chain fatty acid solution :: Colomed :: Treatment of the active phase of ulcerative colitis with involvement restricted to the left side of the colon. :: 29-05-1990 :: Richard I. Breuer :: 1000 Central Street, Suite 615 :: Evanston IL 60201Silver sulfadiazine and cerium nitrate :: Flammacerium :: Prevention of mortality in severely burned patients. :: 17-11-1999 :: Synthes (USA) :: 1690 Russell Road :: PO Box 1766 :: Paoli PA 19301 siplizumab :: Treatment of T-cell lymphomas :: 15-07-2003 :: MedImmune, LLC :: One MedImmune Way :: Gaithersburg 20878Sitaxsentan Sodium :: For the treatment of pulmonary arterial hypertension in the absence of chronic obstructive pulmonary disease or congestive heart failure. :: 02-11-2004 :: Pfizer Global Research and Development :: 50 Pequot Avenue 6025-B4137 :: New London CT 06320SK&F 110679 :: For the long term treatment of children who have growth failure due to a lack of adequate endogenous growth hormone secretion. :: 23-05-1990 :: SmithKline Beecham Pharmaceuticals :: One Franklin Plaza :: Philadelphia PA 19101sodium 2, 2 dimethylbutyrate :: Treatment of sickle cell disease. :: 25-07-2008 :: HemaQuest Pharmaceuticals, Inc. :: 101 Federal Street :: Boston MA 02110sodium 4-{ [9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido [5,4-d] [2] benzazepin-2-yl]-2-methoxybenzoate :: Treatment of ovarian cancer :: 03-04-2009 :: Millennium Pharmaceuticals, Inc. :: 40 Landsdowne Street :: Cambridge MA 02139Sodium aluminosilicate :: Treatment of chronic hepatic encephalopathy :: 04-03-2005 :: Framework Therapeutics, LLc :: 1564 33rd Street, NW :: Washington DC 20007Sodium ascorbate and menadione sodium bisulfite :: Apatone :: Treatment of metastatic or locally advanced inoperable transitional cell carcinoma of the urothelium (stage III and IV bladder cancer) :: 31-07-2007 :: IC-MedTech Corporation :: 9902 Indian Creek Lane :: El Cajon CA 92021Sodium dichloroacetate :: Treatment of homozygous familial hypercholesterolemia. :: 11-06-1990 :: Stacpoole, Peter W. M.D., Ph.D. :: University of Florida :: P.O. Box 100277 :: Gainesville FL 32610 Sodium dichloroacetate :: Treatment of congenital lactic acidosis. :: 11-06-1990 :: Stacpoole, Peter W. M.D., Ph.D. :: University of Florida :: P.O. Box 100277 :: Gainesville FL 32610 Sodium dichloroacetate :: Treatment of congenital lactic acidosis. :: 31-12-1997 :: Questcor Pharmaceuticals, Inc. :: 3260 Whipple Rd. :: Union City CA 94587-1217 Sodium dichloroacetate :: Treatment of lactic acidosis in patients with severe malaria. :: 10-11-1994 :: Stacpoole, Peter W. M.D., Ph.D. :: University Of Florida :: P.O. Box 100277 :: Gainesville FL 32610 sodium dichloroacetate :: Use as an antidote in the management of systemic monochloroacetic acid poisoning :: 03-07-2003 :: EBD Group :: 2032 Corte del Nogal :: Suite 120 :: Carlsbad CA 92011 Sodium dichloroacetate :: Ceresine :: Treatment of severe head injury. :: 14-06-1999 :: Questcor Pharmaceuticals, Inc. :: 3260 Whipple Rd. :: Union City CA 94587-0700 Sodium Monomercaptoundecahydro-closo-dodecaborate :: Borocell :: For use in boron neutron capture therapy (BNCT) in the treatment of glioblastoma multiforme. :: 15-04-1992 :: Neutron Technology Corp.& Neutron R&D Partner :: 877 Main Street, Suite 402 :: Boise ID 83702Sodium monomercaptoundecahydro-closo-dodecaborate :: For use in conjunction with a thermal or epithermal neutron beam in boron nuclear capture therapy of glioblastoma multiforme. :: 18-12-1984 :: Theragenics Corporation Sodium nitrite :: Treatment of vaso-occlusive crisis associated with sickle cell disease :: 02-04-2007 :: Hope Pharmaceuticals, Inc :: 8260 E. Gelding Drive #104 :: Scottsdale AZ 85260Sodium nitrite :: Treatment of cyanide poisoning :: 18-04-2007 :: Hope Pharmaceuticals :: 8260 East Gelding Drive :: Scottsdale AZ 85260Sodium nitrite :: Prevention of vasospasm associated with subarachnoid hemorrhage :: 17-01-2007 :: Hope Pharmaceuticals :: 8260 E. Gelding Drive :: Scottsdale AZ 85260sodium nitrite :: Treatment of pulmonary arterial hypertension :: 08-07-2008 :: Aires Pharmaceuticals, Inc. :: 4690 Executive Drive :: Suite 150 :: San Diego CA 92121 Sodium nitrite and sodium thiosulfate :: Cyanide Antidote Kit :: Treatment of known or suspected cyanide poisoning :: 09-04-2008 :: Hope Pharmaceuticals :: 8260 E. Gelding Drive :: Scottsdale AZ 85260Sodium nitrite/sodium thiosulfate :: Cyanide Antidote Package :: Treatment of cyanide poisoning :: 23-03-2007 :: Keystone Pharmaceuticals, Inc. :: 26072 Merit Circle :: Laguna Hills CA 92653Sodium phenylacetate/sodium benzoate 10%/10% Injection :: Ammonul :: Treatment of grade III and IV hepatic encephalopathy :: 03-06-2005 :: Ucyclyd Pharma, Inc. :: 8125 North Hayden Road :: Scottsdaale AZ 85258Sodium phenylbutyrate :: Treatment of spinal muscular atrophy :: 20-03-2007 :: Tikvah Therapeutics, Inc. :: 75 5th Street, NW. :: Atlanta GA 30308Sodium phenylbutyrate :: Buphenyl :: Treatment of spinal muscular atrophy :: 25-01-2007 :: Ucyclyd Pharma, Inc. :: 8125 N. Hayden Road :: Scottsdale AZ 85258Sodium phenylbutyrate :: For use as an adjuct to surgery, radiation therapy and chemotherapy for the treatment of patients with primary or recurrent malignant glioma. :: 24-04-1998 :: Elan Drug Delivery, Inc. :: 1300 Gould Dr. :: Gainesville GA 30504sodium phenylbutyrate :: Treatment for sickling disorders, which include S-S hemoglobinopathy, S-C hemoglobinopathy, and S-thalassemia hemoglobinopathy. :: 02-07-1992 :: Medicis Pharmaceutical Corp. :: 8125 N. Hayden Road :: Scottsdale AZ 85258Sodium pyruvate :: Treatment of cystic fibrosis :: 31-03-2003 :: Cellular Sciences, Inc. :: 84 Park Avenue :: P. O. Box 968 :: Flemington NJ 08822 Sodium stibogluconate :: Treatment of cutaneous leishmaniasis :: 16-06-2006 :: VioQuest Pharmaceuticals, Inc. :: 180 Mt. Airy Road :: Suite 102 :: Basking Ridge NJ 07920 Sodium thiosulfate :: Prevention of platinum-induced ototoxicity in pediatric patients :: 17-03-2004 :: Adherex Technologies, Inc. :: 4620 Creekstone Drive :: Suite 200 :: Durham NC 27703 Sodium thiosulfate and sodium nitrite :: Treatment of cyanide poisoning :: 18-12-2006 :: Akorn, Inc. :: 2500 Millbrook Drive :: Buffalo Grove IL 60089Sodium thiosulfate, sodium nitrite, amyl nitrite :: Cyanide Antidote Package :: Treatment of cyanide poisoning :: 16-06-2006 :: Keystone Pharmaceuticals, Inc. :: 26072 Merit Circle :: Laguna Hills CA 92653Solasonine and solamargine :: Coramsine :: Treatment of renal cell carcinoma :: 02-11-2005 :: Solbec Pharmaceuticals Limited :: P. O. Box 2142 :: WA 6018 :: AUSTRALIASolasonine and solamargine :: Coramsine :: Treaatment of high risk stage II, stage III and stage IV melanoma :: 06-02-2006 :: Solbec Pharmaceuticals Limited :: P. O. Box 2142 :: Osbourne Park, Western Australia 6017 :: AUSTRALIASoluble complement receptor type 1 :: Prevention of post-cardiopulmonary bypass syndrome in children undergoing cardiopulmonary bypass. :: 06-03-2000 :: Avant Immunotherapeutics, Inc. :: 119 Fourth Ave. :: Needham MA 02494-2725 Soluble recombinant human complement receptor type 1 :: Prevention or reduction of adult respiratory distress syndrome. :: 21-11-1994 :: T Cell Sciences, Inc. :: 119 Fourth Avenue :: Needham Heights MA 02194Solvent/detergent treated non-blood group specific human coagulation active plasma :: UNIPLAS :: Treatment of thrombotic thrombocytopenic purpura :: 12-12-2005 :: Octapharma USA, Inc. :: 121 River Street :: 12th Floor :: Hoboken NJ 07030 Somatostatin :: Zecnil :: Adjunct to the non-operative management of secreting cutaneous fistulas of the stomach, duodenum, small intestine (jejunum and ileum), or pancreas. :: 20-06-1988 :: Ferring Laboratories, Inc. :: 400 Rella Boulevard, Suite 201 :: Suffern NY 10901Somatostatin :: Treatment of bleeding esophageal varices. :: 22-12-1994 :: UCB, Inc. :: 1950 Lake Park Drive :: Smyrna GA 30080Somatrem for injection :: Protropin :: Treatment of short stature associated with Turner's syndrome. :: 09-12-1985 :: Genentech, Inc. :: 460 Point San Bruno Boulevard :: South San Francisco CA 94080Somatropin :: Humatrope :: Treatment of short stature in pediatric patients with short stature homeobox-containing gene (SHOX) deficiency :: 15-12-2005 :: Eli Lilly and Company :: Lilly Corporate Center :: Indianapolis IN 46285Somatropin :: Norditropin :: Treatment of short stature associated with Turner's syndrome. :: 05-11-1987 :: Novo Nordisk Pharmaceuticals :: 100 Overlook Center :: Suite 200 :: Princeton NJ 08540 Somatropin :: Norditropin :: Adjunct for the induction of ovulation in women with infertility due to hypogonadotropic hypogonadism or bilateral tubal occlusion or unexplained infertility, who are undergoing in vivo or in vitro fertilization procedures. :: 01-09-1987 :: Novo Nordisk Pharmaceuticals :: 100 Overlook Center :: Suite 200 :: Princeton NJ 08540 Somatropin :: Biotropin :: Treatment of cachexia associated with AIDS. :: 12-02-1993 :: Bio-Technology General Corp. :: 70 Wood Avenue, South :: Iselin NJ 08830Somatropin :: Serostim :: Treatment of patients with HIV-associated adipose redistribution syndrome :: 16-03-2004 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370Somatropin (rDNA) :: Saizen :: For the enhancement of nitrogen retention in hospitalized patients suffering from severe burns. :: 03-05-1989 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370Somatropin (r-DNA) for injection :: Serostim :: Treatment of children with AIDS-associated failure-to-thrive including AIDS-associated wasting. :: 26-03-1996 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370Sorafenib :: Nexavar :: Treatment of stage IIB through stage IV melanoma :: 29-09-2006 :: Bayer Pharmaceuticals Corp. :: 400 Morgan Lane :: New Haven CT 06516Sorivudine :: BRAVAVIR :: Treatment of herpes zoster (shingles) in immunocompromised patients. :: 09-11-1995 :: Bristol-Myers Squibb :: 5 Research Parkway :: P.O. Box 5100 :: Wallingford CT 06492 Sotalol HCl :: Betapace :: Prevention of life threatening ventricular tachyarrhythmias. :: 23-09-1988 :: Berlex Laboratories, Inc. :: 300 Fairfield Road :: Wayne NJ 07470spherical carbon adsorbent :: Treatment of chronic pouchitis :: 19-12-2007 :: Ocera Therapeutics, Inc. :: 12651 High Bluff Drive :: San Diego CA 92130Spiramycin :: Rovamycine :: For symptomatic relief and parasitic cure of chronic cryptosporidiosis in patients with immunodeficiency. :: 17-10-1984 :: Rhone-Poulenc Rorer Pharmaceuticals :: 500 Arcola Road :: Collegeville PA 19426squalamine lactate :: Treatment of ovarian cancer refractory or resistant to standard chemotherapy :: Treatment of ovarian cancer :: 11-05-2001 :: Genaera Corporation :: 5110 Campus Drive :: Plymouth Meeting PA 19462SS1(dsFv)-PE38 :: Treatment of epithelial ovarian cancer :: 11-02-2002 :: National Institutes of Health :: Cancer Therapy Evaluation Program/DCTD/NCI :: Suite 7111 :: Rockville MD 20852 SS1(dsFv)-PE38 :: Treatment of malignant mesothelioma :: 11-02-2002 :: National Institutes of Health :: Cancer Therapy Evaluation Program :: NCI/DCTD :: Rockville MD 20852 ST1-RTA immunotoxin (SR 44163) :: Treatment of patients with B-chronic lymphocytic leukemia. :: 12-08-1987 :: Sanofi Winthrop, Inc. :: 9 Great Valley Parkway :: Malvern PA 19355ST1-RTA immunotoxin (SR 44163) :: Prevention of acute graft versus host disease in allogenic bone marrow transplantation. :: 12-08-1987 :: Sanofi Winthrop, Inc. :: 9 Great Valley Parkway :: Malvern PA 19355Staphylococcus aureus Immune Globulin (Human) :: Altastaph :: Prophylaxis against Staphylococcus aureus infections in low birth weight neonates :: 29-01-2004 :: Biotest Pharmaceuticals Corporation :: 5800 Park of Commerce Blvd, NW :: Boca Raton FL 33487Stem and progenitor cells derived from ex vivo expanded allogeneic umbilical cord blood :: StemEx :: For use as hematopoietic support in patients with relasped or refractory hematologic malignancies who are receiving high-dose therapy :: 04-03-2005 :: Gamida Cell Ltd :: 5, Nahum Hafzadi St. :: Jerusalem 95484 :: ISRAELSterile talc :: Steritalc :: Treatment of malignant pleural effusion. :: 08-12-1997 :: Novatech SA :: Avenue du Vent des Dames – Z.l. les Paluds :: 13685 Aubagne :: FRANCESterile talc :: Steritalc :: Treatment of pneumothorax. :: 08-12-1997 :: Novatech SA :: Avenue du Vent des Dames – Z.l. les Paluds :: 13685 Aubagne :: FRANCEstiripentol :: diacomit(r) :: Treatment of Dravet syndrome :: 30-10-2008 :: Biocodex :: 7, avenue Gallieni :: 94250 Gentilly :: FRANCESU101 :: Treatment of ovarian cancer. :: 12-03-1996 :: Sugen, Inc. :: 230 East Grand Ave. :: South San Francisco CA 94080-4811 SU101 :: Treatment of malignant glioma. :: 25-05-1995 :: Sugen, Inc. :: 230 East Grand Ave. :: South San Francisco CA 94080-4811 Succimer :: Chemet :: Treatment of mercury intoxication. :: 22-03-1991 :: Sanofi Winthrop, Inc. :: 90 Park Avenue :: New York NY 10016-1389 Succimer :: Chemet :: Prevention of cystine kidney stone formation in patients with homozygous cystinuria who are prone to stone development. :: 05-11-1990 :: Sanofi Winthrop, Inc. :: 90 Park Avenue :: New York NY 10016-1389 Sucralfate :: Treatment of oral mucositis and stomatitis following radiation therapy for head and neck cancer. :: 15-07-1993 :: Fuisz Technologies, Ltd. :: 14555 Avion at Lakeside :: Chantilly VA 20151Sucralfate suspension :: Treatment of oral complications of chemotherapy in bone marrow transplant patients. :: 12-03-1990 :: Darby Pharmaceuticals, Inc. :: 100 Banks Avenue :: Rockville Centre NY 11570Sucralfate suspension :: Treatment of oral ulcerations and dysphagia in patients with epidermolysis bullosa. :: 04-03-1991 :: Darby Pharmaceuticals, Inc. :: 100 Banks Avenue :: Rockville Centre NY 11570sulfamidase :: For treatment of Sanfilippo Syndrome. :: 22-05-2008 :: Shire Human Genetic Therapies, Inc. :: 700 Main Street :: Cambridge MA 02139Sulfapyridine :: Treatment of dermatitis herpetiformis. :: 10-09-1990 :: Jacobus Pharmaceutical Company :: 37 Cleveland Lane :: P.O. Box 5290 :: Princeton NJ 08540 Superoxide dismutase (human) :: For protection of donor organ tissue from damage or injury mediated by oxygen-derived free radicals that are generated during the necessary periods of ischemia (hypoxia, anoxia), and especially reperfusion, associated with the operative procedure. :: 06-03-1985 :: Pharmacia-Chiron Partnership :: 4560 Horton Street :: Emeryville CA 94608Superoxide dismutase (recombinant human) :: Oxsodrol :: Prevention of reperfusion injury to donor organ tissue. :: 17-05-1988 :: Bio-Technology General Corp. :: 70 Wood Avenue, South :: Iselin NJ 08830Suramin :: Metaret :: Treatment of hormone-refractory prostate cancer. :: 06-05-1997 :: Warner-Lambert Company :: Parke-Davis Pharmaceutical Research Division :: 2800 Plymouth Road :: Ann Arbor MI 48105-2430Surfactant (human) (amniotic fluid derived) :: Human Surf :: Prevention and treatment of neonatal respiratory distress syndrome. :: 25-03-1987 :: Merritt, T. Allen M.D. :: 2516 Stockton Boulevard :: Sacramento CA 95817Synsorb Pk :: Treatment of verocytotoxogenic E. coli infections. :: 17-07-1995 :: Synsorb Biotech Inc. :: 201, 1204 Kensington Road, N.W. :: Calgary, Alberta :: CANADASynthetic Human Parathyroid Hormone 1-34 :: Treatment of hypoparathyroidism :: 26-01-2001 :: Rare Disease Therapeutics, Inc. :: 2550 Meridian Blvd :: Nashville TN 37217Synthetic human secretin :: For use in conjunction with diagnostic procedures (excluding ERCP) for pancreatic disorders to increase pancreatic fluid secretion :: 18-09-2006 :: Repligen Corporation :: 41 Seyon Street :: Waltham MA 02453Synthetic human secretin :: For use in the diagnosis of gastrinoma associated with Zollinger-Ellison syndrome. :: 16-06-1999 :: ChiRhoClin, Inc. :: 15500 Gallaudet Ave. :: Silver Spring MD 20905-4176 Synthetic human secretin :: For use in conjunction with diagnostic procedures for pancreatic disorders to increase pancreatic fluid secretion. :: 07-03-2000 :: ChiRhoClin, Inc. :: 15500 Gallaudet Ave. :: Silver Spring MD 20905-4176 Synthetic human secretin :: For use in obtaining desquamated pancreatic cells for cytopathologic examination in pancreatic carcinoma. :: 16-06-1999 :: ChiRhoClin, Inc. :: 15500 Gallaudet Ave. :: Silver Spring MD 20905-4176 Synthetic human secretin :: "For use in the evaluation of exocrine pancreas function." :: 16-06-1999 :: ChiRhoClin, Inc. :: 1550 Gallaudet Ave. :: Silver Spring MD 20905-4176 Synthetic porcine secretin :: For use in obtaining desquamated pancreatic cells for cytopathologic examination in pancreatic carcinoma. :: 18-06-1999 :: ChiRhoClin, Inc. :: 15500 Gallaudet Ave. :: Silver Spring MD 20905-4176 T4 endonuclease V, liposome encapsulated :: To prevent cutaneous neoplasms and other skin abnormalities in xeroderma pigmentosum. :: 27-06-1989 :: AGI Dermatics :: 205 Buffalo Avenue :: Freeport NY 11520Tacrolimus :: Prograf :: Prophylaxis of graft-versus-host-disease. :: 06-04-1998 :: Fujisawa USA, Inc. :: 3 Parkway North Center :: Deerfield IL 60015Tadalafil :: Cialis :: Treatment of pulmonary arterial hypertension :: 18-12-2006 :: Eli Lilly and Company :: Lilly Corporate Center :: Indianapolis IN 46285TAK-603 :: Treatment of Crohn's disease. :: 13-05-1998 :: Tap Holdings Inc. :: 2355 Waukegan Road :: Deerfield IL 60015Talactoferrin alfa :: Treatment of non-small cell lung cancer :: 08-08-2007 :: Agennix, Inc. :: 8 Greenway Plaza :: Houston TX 77046talactoferrin alfa :: Treatment of renal cell carcinoma :: 29-09-2006 :: Agennix, Inc. :: 8 Greenway Plaza :: Suite 910 :: Houston TX 77046 talactoferrin alfa :: For the treatment of graft versus host disease :: 20-08-2003 :: Agennix, Inc. :: Greenway Plaza :: Suite 910 :: Houston TX 77046 talactoferrin alfa :: For the prevention of graft-versus-host disease :: 20-08-2003 :: Agennix, Inc. :: 8 Greenway Plaza :: Suite 910 :: Houston TX 77046 talampanel :: Treatment of glioma :: 17-02-2009 :: TEVA Neuroscience, Inc. :: 425 Privet Road :: Horsham PA 19044-8005 talampanel :: Treatment of amyotrophic lateral sclerosis :: 24-03-2008 :: TEVA Neuroscience :: P. O. Box 1005 :: Horsham PA 19044-8005 Tamibarotene :: Treatment of acute promyelocytic leukemia (APL). :: 11-10-2007 :: CytRx Corporation :: 3030 Bunker Hill Road :: Suite 101 :: San Diego CA 92109 Tanespimycin :: Treatment of multiple myeloma :: 09-09-2004 :: Bristol-Myers Squibb :: research and Development :: 5 Research Parkway :: Wallingford CT 06492-7660"T-cell depleted stem cell enriched cellular product from peripheal blood stem cells" :: Treatment of chronic granulomatous disease :: 01-11-2001 :: Nexell Therapeutics Inc. :: 9 Parker :: Irvine CA 92618-1605 TD-K6a.513a.12 :: ReveKer :: Treatment of pachyonychia congenita :: 15-06-2006 :: TransDerm, Inc. :: 2161 Delaware Aenue :: Santa Cruz CA 95060Technetium Tc 99m pterotetramide :: For the identification of ovarian carcinomas. :: 16-02-2000 :: Endocyte, Inc. :: 1205 Kent Ave. :: West Lafayette IN 47906Technetium Tc99m anti-melanoma murine monoclonal antibody :: Oncotrac Melanoma Imaging Kit :: For use in detecting, by imaging, metastases of malignant melanoma. :: 02-06-1987 :: NeoRx Corporation :: 410 West Harrison :: Seattle WA 98119-4007 Technetium Tc99m murine monoclonal antibody (IgG2a) to B cell :: LymphoScan :: Diagnostic imaging in the evaluation of the extent of disease in patients with histologically confirmed diagnosis of non-Hodgkin's B-cell lymphoma, acute B-cell lymphoblastic leukemia (in children and adults), and chronic B-cell lymphocytic leukemia. :: 07-04-1992 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Technetium Tc99m murine monoclonal antibody to hCG :: Immuraid, hCG-Tc-99m :: Detection of hCG producing tumors such as germ cell and trophoblastic cell tumors. :: 07-08-1989 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Technetium Tc99m murine monoclonal antibody to human AFP :: AFP-Scan :: Detection of alpha-fetoprotein producing germ cell tumors. :: 01-08-1989 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Technetium Tc99m murine monoclonal antibody to human alpha-fetoprotein :: Immuraid, AFP-Scan :: Detection of hepatocellular carcinoma and hepatoblastoma. :: 01-08-1989 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Technetium Tc99m rh-Annexin V :: Apomate :: Diagnosis or assessment of rejection status in heart, heart-lung, single lung, or bilateral lung transplants. :: 03-11-2000 :: Theseus Imaging Corporation :: 124 Mount Auburn Street :: Suite 200 North :: Cambridge MA 02138 Tegafur/gimeracil/oteracil :: Treatment of gastric cancer :: 20-07-2006 :: Taiho Pharma USA, Inc. :: 210 Carnegie Center :: Princeton NJ 08540temocillin sodium :: Negaban :: Treatment of pulmonary infections caused by Burkholderia cepacia :: 21-04-2004 :: Belpharma N.V. :: 67 Winston Churchill Avenue :: Brussels :: BELGIUMTemoporfin :: Foscan :: Palliative treatment of recurrent, refractory or second primary squamous cell carcinomas of the head and neck in patients considered to be incurable with surgery or radiotherapy. :: 28-10-1999 :: Biolitec Pharma Ireland Ltd. :: United Drug House :: Dublin :: IRELANDTemozolomide :: Temodal :: Treatment of newly diagnosed high grade glioma :: 18-10-2004 :: Schering-Plough Research Institute :: 2000 Galloping Hill Road :: Kenilworth NJ 07033Temozolomide :: Temodal :: Treatment of advanced metastatic melanoma. :: 14-10-1998 :: Schering-Plough Research Institute :: 2000 Galloping Hill Rd. :: Kenilworth NJ 07033tenofovir disoproxil fumarate :: Viread(r) :: Treatment of pediatric HIV infection. :: 17-03-2009 :: Gilead Sciences, Inc. :: 333 Lakeside Drive :: Foster city CA 94404terguride :: Treatment of pulmonary arterial hypertension :: 01-05-2008 :: ErgoNex Pharma GmbH :: Ruetistr. 20 :: CH-9050 Appenzell :: SWITZERLANDTeriparatide :: Parathar :: Treatment of idiopathic osteoporosis. :: 28-10-1999 :: Biomeasure, Inc. :: 27 Maple St. :: Milford MA 01757-3650 Terlipressin :: Glypressin :: Treatment of bleeding esophageal varices. :: 06-03-1986 :: Ferring Laboratories, Inc. :: 400 Rella Boulevard, Suite 201 :: Suffern NY 10901Terlipressin (INN) :: Treatment of Hepatorenal Syndrome :: Fast Track granted by CDER. A rolling NDA submission is planned by the sponsor. :: 29-10-2004 :: Orphan Therapeutics, LLC :: 3 Werner Way :: Round Valley Executive Center :: Lebanon NJ 08833 tesetaxel :: Treatment of stages IIB, IIC, III, and stage IV melanoma :: 21-11-2008 :: Genta, Inc. :: 200 Connell Drive :: Berkley Heights NJ 07922tesetaxel :: Treatment of gastric cancer :: 22-12-2008 :: Genta Inc. :: 200 Connell Drive :: Berkeley Heights NJ 07922Testosterone :: TheraDerm Testosterone Transdermal System :: For use as physiologic testosterone replacement in androgen deficient HIV+ patients with an associated weight loss. :: 22-09-1997 :: Watson Laboratories :: Research Park :: 417 Wakara Way :: Salt Lake City UT 84108 Testosterone propionate ointment 2% :: Treatment of vulvar dystrophies. :: 31-07-1991 :: Star Pharmaceuticals, Inc. :: 1990 N.W. 44th Street :: Pompano Beach FL 33064Testosterone sublingual :: Treatment of constitutional delay of growth and puberty in boys. :: 16-01-1991 :: Bio-Technology General Corp. :: 70 Wood Avenue South :: Iselin NJ 08830Tetrabenazine :: Treatment of moderate/severe tardive dyskinesia. :: 12-05-1998 :: Prestwick Pharmaceuticals, Inc. :: 1825 K Street, NW :: Suite 1475 :: Washington DC 20006 Tetraiodothyroacetic acid :: Suppression of thyroid stimulating hormone in patients with well-differentiated cancer of the thyroid gland. :: 01-05-2000 :: Danforth, Jr., MD, Elliot :: University of Vermont :: 84 Beartown Rd. :: Underhill VT 05489 Tezacitabine :: Treatment of adenocarcinoma of the esophagus and stomach :: 27-01-2003 :: Sanofi-Aventis Pharma :: 9 Great valley Parkway :: Malvern PA 19355-1304 TGF(beta)2-specific phosphorothioate antisense oligodeoxynucleotide :: Oncomun :: Treatment of malignant glioma :: 05-06-2002 :: Antisense Pharma GmbH :: Josef-Engert-Str. 9 :: 93053 Regensberg :: GERMANYTGp1PTH1-34 :: Treatment of solitary (unicameral) bone cysts. :: 01-02-2007 :: Kuros Biosurgery AG :: Technoiparkstrasse 1 :: Zurich :: SWITZERLANDThalidomide :: Thalomid :: Treatment of myelodysplastic syndrome :: 27-09-2004 :: Celgene Corporation :: 86 Morris Avenue :: Summit NJ 07901Thalidomide :: Treatment and prevention of recurrent aphthous ulcers in severely, terminally immunocompromised patients. :: 15-05-1995 :: Andrulis Research Corporation :: 11800 Baltimore Avenue, Suite 113 :: Beltsville MD 20705Thalidomide :: Synovir :: Treatment of HIV-associated wasting syndrome. :: 11-03-1996 :: Celgene Corporation :: P.O. Box 4914 :: 7 Powder Horn Drive :: Warren NJ 07059 Thalidomide :: Thalomid :: Treatment of Crohn's disease. :: 06-04-1999 :: Celgene Corporation :: 7 Powder Horn Dr. :: Warren NJ 07059Thalidomide :: Prevention of graft versus host disease in patients receiving bone marrow transplantation. :: 19-09-1988 :: Pediatric Pharmaceuticals, Inc. :: 718 Bradford Avenue :: Westfield NJ 07090Thalidomide :: Treatment of graft versus host disease in patients receiving bone marrow transplantation. :: 19-09-1988 :: Pediatric Pharmaceuticals, Inc. :: 718 Bradford Avenue :: Westfield NJ 07090Thalidomide :: Treatment and maintenance of reactional lepromatous leprosy. :: 15-11-1988 :: Pediatric Pharmaceuticals, Inc. :: 718 Bradford Avenue :: Westfield NJ 07090Thalidomide :: Treatment of the clinical manifestations of mycobacterial infection caused by Mycobacterium tuberculosis and non-tuberculous mycobacteria. :: 12-01-1993 :: Celgene Corporation :: P.O. Box 4914 :: 7 Powder Horn Drive :: Warren NJ 07059 Thalidomide :: Prevention of graft versus host disease. :: 05-03-1990 :: Andrulis Research Corporation :: 11800 Baltimore Avenue, Suite 113 :: Beltsville MD 20705Thalidomide :: Treatment of graft versus host disease. :: 05-03-1990 :: Andrulis Research Corporation :: 11800 Baltimore Avenue, Suite 113 :: Beltsville MD 20705Thalidomide :: Treatment of primary brain malignancies. :: 27-02-1998 :: Celgene Corporation :: 7 Powder Horn Dr. :: Warren NJ 07059Thalidomide :: Treatment of severe recurrent aphthous stomatitis in severely, terminally immunocompromised patients. :: 01-05-1995 :: Celgene Corporation :: P.O. Box 4914 :: 7 Powder Horn Srive :: Warren NJ 07059 Thalidomide :: Treatment of Kaposi's sarcoma. :: 29-07-1998 :: Celgene Corporation :: 7 Powder Horn Dr. :: Warren NJ 07059Thiotepa :: Tepadina :: Conditioning treatment prior to hematopoietic stem cell transplantation :: 02-04-2007 :: Adienne S.r.l. :: 24128 Bergamo, 64/B Broseta Street :: Bergamo :: ITALYThymalfasin :: Zadaxin :: Treatment of stage IIb through Stage IV malignant melanoma :: 13-03-2006 :: SciClone Pharmaceuticals, Inc. :: 901 Mariner's Island Blvd :: San Mateo CA 94404Thymalfasin :: Zadaxin :: Treatment of chronic active hepatitis B. :: 03-05-1991 :: SciClone Pharmaceuticals, Inc. :: 950 Tower Lane :: Suite 900 :: Foster City CA 94404-2125Thymalfasin :: Zadaxin :: Treatment of DiGeorge anomaly with immune defects. :: 08-01-1998 :: SciClone Pharmaceuticals, Inc. :: 901 Mariner's Island Blvd. :: San Mateo CA 94404-1593 Thymalfasin :: Zadaxin :: Treatment of hepatocellular carcinoma. :: 06-03-2000 :: SciClone Pharmaceuticals, Inc. :: 901 Mariner's Blvd., Suite 205 :: San Mateo CA 94404-1593 Thymosin beta 4 :: Treatment of epidermolysis bullosa :: 28-05-2004 :: RegeneRx Biopharmaceuticals, Inc. :: 3 Bethesda Metro Center :: Suite 700 :: Bethesda MD 20814 Thymoxamine HCl :: Reversal of phenylephrine-induced mydriasis in patients who have narrow anterior angles and are at risk of developing an acute attack of angle-closure glaucoma following mydriasis. :: 16-11-1987 :: Iolab Pharmaceuticals :: 500 Iolab Drive :: Claremont CA 91711Tiapride :: Treatment of Tourette's syndrome. :: 21-04-1998 :: Sanofi-Synthelabo, Inc. :: 9 Great Valley Parkway :: PO Box 3026 :: Malvern PA 19355 Tiazofurin (2-Beta-D-ribofuranosyl-4-thiazolecarboxamide) :: Chronic myelogenous leukemia (CML) :: 27-12-2000 :: Valeant Research & Development :: 3300 Hyland Avenue :: Costa Mesa CA 92626Tilarginine acetate :: Treatment of cardiogenic shock :: 11-04-2005 :: Arginox Pharmceuticals, Inc. :: 120 Constitution Drive :: Menlo Park CA 94025tin ethyl etiopurpurin :: Prevention of access graft disease in hemodialysis patients :: 04-11-2003 :: Miravant Medical Technologies :: 336 Bollay Drive :: Goleta CA 93117Tiotropium bromide :: Spiriva :: To improve pulmonary function in conjunction with standard therapy in the management of patients with cystic fibrosis :: 08-01-2008 :: Boehringer Ingelheim Pharmaceuticals, Inc. :: P. O. Box 368 :: 900 Ridgebury Road :: Ridgefield CT 06877 Tipifarnib :: Zarnestra :: Treatment of acute myeloid leukemia :: 06-07-2004 :: Johnson & Johnson Pharmaceutical Research & Dev. :: 920 U.S. Highway 202 :: Raritan NJ 08869tirapazamine :: Treatment of head and neck cancer :: 23-10-2002 :: Sanofi-Aventis US, Inc. :: 11 Great Valley Parkway :: P. O. Box 3026 :: Malvern PA 19355 Tiratricol :: Triacana :: For use in combination with levo-thyroxine to suppress thyroid stimulating hormone in patients with well-differentiated thyroid cancer who are intolerant to adequate doses of levo-thyroxine alone. :: 13-08-1991 :: Laphal Laboratoires :: 48 Bis, Rue des Belles-Feuilles :: 75116 Paris :: FRANCETissue repair cells obtained from autologous bone marrow expanded ex vivo with a cell production system :: Treatment of osteonecrosis :: 13-03-2006 :: Aastrom Biosciences, Inc. :: Domino's Farms :: 24 Frank Lloyd Wright Drive :: Ann Arbor MI 48105 Tissue repair cells obtained from autologous bone marrow expanded ex vivo with a cell production system :: Treatment of dilated cardiomyopathy :: 25-01-2007 :: Aastrom Biosciences, Inc. :: Domino's Farms, Lobby L :: Ann Arbor MI 48105Titanium dioxide and bisoctrizole :: For the secondary prevention (prevention of lesional induction) of disorders with UV-A and visible light-induced photosensitivity, specifically Actinic prurigo, Hydroa vacciniforme, Solar urticara (SU), Chronic Actinic Dermatitis (CAD), the cutaneous prop :: 25-05-2005 :: Orfagen :: Parc Technologique Du Canal-4 :: 31521 Ramonville Saint Agne :: FRANCETizanidine HCl :: Zanaflex :: Treatment of spasticity associated with multiple sclerosis and spinal cord injury. :: For the acute and intermittent management of increased muscle tone associated with spasticity. :: 31-01-1994 :: Athena Neurosciences, Inc. :: 800 Gateway Boulevard :: South San Francisco CA 94080Tobramycin :: Tobi :: Treatment of bronchiectasis patients infected with Pseudomonas aeruginosa. :: 18-06-1999 :: Novartis Pharmaceuticals Corp. :: Drug Regulatory Affairs :: One Health Plaza :: East Hanover NJ 07936-1080tobramycin liposomal for inhalation :: Fluidosomes :: Treatment of chronic pulmonary infection due to P. aeruginosa in cystic fibrosis patients :: 14-04-2009 :: Axentis Pharma AG :: 138 Limmatquai :: CH-8001 :: Zurich :: SWITZERLANDTocophersolan oral solution (vitamin E-tpgs) :: Treatment of vitamin E deficiency resulting from malabsorption due to prolonged cholestatic hepatobiliary disease. :: 15-04-1988 :: Sterling Winthrop :: 9 Great Valley Parkway :: Malvern PA 19355toralizumab :: Treatment of immune thrombocytopenic purpura :: 14-03-2002 :: Biogen IDEC Inc. :: 3030 Callan Road :: San Diego CA 92121Toremifene :: Treatment of desmoid tumors. :: 17-08-1993 :: Orion Corporation :: P.O. Box 65 :: 02101 Espoo :: FINLANDTosedostat :: Treatment of acute myeloid leukemia :: 10-12-2008 :: Chroma Therapeutics Ltd. :: 93 Milton Park :: Oxfordshire OX14 4RY :: UNITED KINGDOMtrabectedin :: Yondelis :: Treatment of soft tissue sarcoma. :: 30-09-2004 :: Johnson & Johnson Pharmaceutical Research & Dev. :: 920 US Highway 202 :: P. O. Box 300 :: Raritan NJ 08869 trabectedin :: Yondelis :: Treatment of patients with ovarian cancer :: 29-03-2005 :: Ortho Biotech Oncology Research & Development :: 920 U S Highway 202 :: Raritan NJ 08869Tramadol hydrochloride :: Management of postherpetic neuralgia :: 26-04-2005 :: TheraQuest Biosciences, LLC :: 146 Medinah Drive :: Blue Bell PA 19422-3212 Tramadol hydrochloride :: Treatment of painful HIV-associated neuropathy :: 28-01-2005 :: TheraQuest Biosciences, LLC :: 146 Medinah Drive :: Blue Bell PA 19422-3212 Tranexamic acid :: Cyklokapron :: Treatment of patients undergoing prostatectomy where there is hemorrhage or risk of hemorrhage as a result of increased fibrinolysis or fibrinogenolysis. :: 23-07-1987 :: Pharmacia Inc. :: P.O. Box 16529 :: Columbus OH 43216Tranexamic acid :: Cyklokapron :: Treatment of hereditary angioneurotic edema. :: 09-09-1985 :: Pharmacia Inc. :: P.O. Box 16529 :: Columbus OH 43216Tranilast :: Rizaben :: For the treatment of maligant glioma :: 02-12-2003 :: Angiogen Pharmaceuticals, Pty. Ltd. :: Level 31, ABN AMRO Tower :: 88 Phillip Street Sydney, N.S.W. 2000 :: AUSTRALIATransforming growth factor-beta 2 :: Treatment of full thickness macular holes. :: 18-12-1992 :: Celtrix Pharmaceuticals, Inc. :: 3055 Patrick Henry Drive :: Santa Clara CA 95054Transgenic human alpha 1 antitrypsin :: Treatment of emphysema secondary to alpha 1 antitrypsin deficiency. :: 19-05-1999 :: PPL Therapeutics (Scotland) Limited :: Roslin, Edinburgh :: EH259PP Scotland :: UNITED KINGDOMTrastuzumab :: Herceptin :: Treatment of patients with pancreatic cancer that overexpress p185HER2. :: 14-12-1999 :: Genentech, Inc. :: 1 DNA Way :: South San Francisco CA 94080-4990 Treosulfan :: Ovastat :: Treatment of ovarian cancer. :: 16-05-1994 :: Medac GmbH :: Fehlandtstrasse 3 :: D-20354 Hamburg :: GERMANYTretinoin :: ATRA-IV :: Treatment of acute and chronic leukemia. :: 14-01-1993 :: Antigenics, Inc. :: 3 Forbes Road :: Lexington MA 02421Tretinoin :: ATRA-IV :: Treatment of T-cell non-Hodgkin's lymphoma :: 11-04-2003 :: Antigenics, Inc. :: 3 Forbes Road :: Lexington MA 02421Tretinoin :: Treatment of squamous metaplasia of the ocular surface epithelia (conjunctiva and/or cornea) with mucous deficiency and keratinization. :: 15-04-1985 :: Hannan Ophthalmic Marketing Services, Inc :: 34 Sherrill Rd. :: Marshfield MA 02050tri-antennary glycotripeptide derivative of 5-fluorodeoxyuridine monophosphate :: Treatment for hepatocellular carcinoma :: 23-11-2001 :: Cell Works Inc. :: 6200 Seaforth Street :: Baltimore MD 21224-6506 triciribine :: Treatment of multiple myeloma :: 01-02-2008 :: VioQuest Pharmaceuticals, Inc. :: 180 Mt. Airy Road :: Basking Ridge NJ 07920Triheptanoin :: Triheptanoin-SASOL Special Oil :: Treatment of glycogen storage disorder II (Pompe disease) :: 01-02-2008 :: Baylor Research Institute :: 3330 Live Oak Blvd :: Dallas TX 75204Triheptanoin :: Triheptanoim-SASOl Special Oil :: Treatment of fatty acid disorders :: 26-05-2006 :: Baylor Research Institute :: Institute of Metabolic Disease :: 3812 Elm Street :: Dallas TX 75226 Trimetrexate :: Neutrexin :: Treatment of metastatic osteogenic sarcoma. :: 10-08-2000 :: Medimmune Oncology, Inc. :: One MedImmune Way :: Gaithersburg MD 20878Trimetrexate glucuronate :: Treatment of patients with advanced non-small cell carcinoma of the lung. :: 13-01-1988 :: Medimmune Oncology, Inc. :: One MedImmune Way :: Gaithersburg MD 20878Trimetrexate glucuronate :: Treatment of pancreatic adenocarcinoma. :: 25-07-1985 :: Medimmune Oncology, Inc. :: One MedImmune Way :: Gaithersburg MD 20878Trimetrexate glucuronate :: Treatment of metastatic colorectal adenocarcinoma. :: 25-07-1985 :: Medimmune Oncology, Inc. :: One MedImmune Way :: Gaithersburg MD 20878Trimetrexate glucuronate :: Treatment of metastatic carcinoma of the head and neck (i.e. buccal cavity, pharynx, and larynx). :: 25-07-1985 :: Medimmune Oncology, Inc. :: One MedImmune Way :: Gaithersburg MD 20878Triptorelin pamoate :: Decapeptyl Injection :: For use in the palliative treatment of advanced ovarian carcinoma of epithelial origin. :: 10-08-1990 :: Debio R.A. Inc. :: 7929 Westpark Drive, Suite 400 :: Mclean VA 22102Trisaccharides A and B :: Biosynject :: Treatment of moderate to severe clinical forms of hemolytic disease of the newborn arising from placental transfer of antibodies against blood group substances A and B. :: 12-04-1987 :: Chembiomed, Ltd. :: P.O. Box 8050, Station F :: Edmonton, Alberta :: CANADATrisaccharides A and B :: Biosynject :: Prevention of ABO medical hemolytic reactions arising from ABO-incompatible bone marrow transplantation. :: 15-04-1988 :: Chembiomed, Ltd. :: P.O. Box 8050 :: Edmonton, Alberta :: CANADATrisaccharides A and B :: Treatment of moderate to very severe clinical forms of transfusion reactions arising from ABO incompatible transfusions of blood, blood products, and blood derivatives. :: 03-08-1987 :: Chembiomed, Ltd. :: P.O. Box 8050 :: Edmonton, Alberta :: CANADATrisaccharides A and B :: Biosynject :: For use in ABO-incompatible solid organ transplantation, including kidney, heart, liver and pancreas. :: 20-04-1987 :: Chembiomed, Ltd. :: P.O. Box 8050 :: Edmonton, Alberta :: CANADATrisodium citrate concentration :: Hemocitrate :: For use in leukapheresis procedures. :: 15-06-1995 :: Hemotec Medical Products, Inc. :: Box 19255 :: Johnston RI 02919Trisodium zinc Diethylenetriaminepentaacetate :: Treatment of patients with known or suspected internal contamination with plutonium, americium, or curium to increase the rate of elimination. :: 27-02-2004 :: CustomCare Pharmacy :: 5710 Hoover Blvd :: Tampa FL 33634Troxacitabine :: Troxatyl :: Treatment of acute myeloid leukemia :: 04-04-2005 :: Structural GenomiX, Inc. (SGX) :: 10505 Roselle Street :: San Diego CA 92121Tumor necrosis factor-binding protein 1 :: Treatment of symptomatic patients with AIDS including all patients with CD4 counts less than 200 cells per mm3. :: 06-01-1993 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370Tumor necrosis factor-binding protein II :: Treatment of symptomatic patients with the AIDS including all patients with CD4 T-cell counts less than 200 cells per mm3. :: 06-01-1993 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370Tyloxapol :: Supervent :: Treatment of cystic fibrosis. :: 08-03-1995 :: Kennedy & Hoidal, M.D.'s :: University of Utah Health Sciences Center :: 50 North Medical Drive, Room 4R240 :: Salt Lake City UT 84132-0001Type 1 native bovine skin collagen :: Treatment of diffuse systemic sclerosis :: 01-02-2008 :: arGentis Pharmaceuticals, LLC :: 20 South Dudley Street :: Memphis TN 38139tyrosine kinase inhibitor :: Treatment of mastocytosis :: 14-09-2005 :: AB Science :: 3, avenue GeorgeV :: 75008 Paris :: FRANCEUbiquinol :: Ubi-Q-Nol, Li-Q-Nol :: Treatment of Huntington's Disease :: 12-04-2004 :: Gel-Tec, Division of Tishcon Corp :: 30 New York Avenue :: P. O. Box 331 :: Westbury NY 11590 Ubiquinol, coenzyme Q10, ubiquinone :: UBI-Q-NOL :: Treatment of pediatric congestive heart failure :: 12-04-2004 :: Gel-Tec, Division of TISHCON Corporation :: 30 New York Avenue :: P.O. Box 331 :: Westbury NY 11590 Ubiquinone :: Ubi-Q-Gel :: Treatment of mitochondrial cytopathies. :: 14-12-1999 :: Gel-Tec, Division of Tishcon Corp. :: 30 New York Ave. :: PO Box 331 :: Westbury NY 11590 Unconjugated Chimeric (human-murine) G250 IgG monoclonal antibody :: Treatment of renal cell carcinoma. :: 22-03-2001 :: Wilex Biotechnology GmbH :: Grillparzerstrasse 10B :: 81675 Munich :: GERMANYUrea for intravitreal injection :: Neurosolve :: Treatment of retinitis pigmentosa :: 14-12-2005 :: Vitreo Retinal Techologies, Inc :: 2 Venture Plaza :: Irvine CA 92618Uridine 5'-triphosphate :: To facilitate the removal of lung secretions in the treatment of patients with primary ciliary dyskinesia. :: 26-06-1996 :: Inspire Pharmaceuticals, Inc. :: 4222 Emperor Boulevard, Suite 470 :: Durham NC 27703Uridine 5'-triphosphate :: Treatment of cystic fibrosis. :: 04-12-1995 :: Inspire Pharmaceuticals, Inc. :: 4222 Emperor Boulevard, Suite 470 :: Durham NC 27703Urofollitropin :: Fertinex :: For the initiation and re-initiation of spermatogenesis in adult males with reproductive failure due to hypothalamic or pituitary dysfunction, hypogonadotropic hypogonadism. :: 05-12-1997 :: EMD Serono, Inc. :: One Technology Place :: Rockland MA 02370Urogastrone :: For acceleration of corneal epithelial regeneration and healing of stromal incisions from corneal transplant surgery. :: 01-11-1984 :: Chiron Vision :: 500 Iolab Drive :: Claremont CA 91711ursodiol :: Ursofalk Suspension :: Treatment of cystic fibrosis liver disease :: 23-10-2007 :: Asklepion Pharmaceuticals, LLC :: 5200 Maryland Way :: Brentwood TN 37027Ursodiol :: Actigall :: Management of the clinical signs and symptoms associated with primary biliary cirrhosis. :: 19-02-1991 :: Novartis Pharmaceuticals Corporation :: 59 Route 10 :: East Hanover NJ 07936-1080 Valine, isoleucine and leucine :: VIL :: Treatment of hyperphenylalaninemia :: 05-01-1996 :: Leas Research Products :: 78 Fallon Drive :: North Haven CT 06473valine-valine-ganciclovir :: Treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HSV1 and HSV2. :: 21-05-2007 :: Verenta Pharmaceuticals, Inc. :: 10901 Granada Lane :: Suite 101 :: Leawood KS 66211 Valproate :: Treatment of fragile X syndrome :: 05-05-2008 :: Neuropharm Ltd, :: Fetcham Park House :: Surrey KT22 9HD :: UNITED KINGDOMValproic acid, sodium :: PEAC :: Treatment of familial adenomatous polyposis :: 24-06-2005 :: Topo Target Germany AG :: Paul-Ehrlich Str. 42-44 :: D-60596 Frankfurt am Main :: GERMANYVandetanib :: Zactima :: Treatment of patients with follicular thyroid carcinoma, medullary thyroid carcinoma, anaplastic thyroid carcinoma, and locally advanced and metastatic papillary thyroid carcinoma :: 21-10-2005 :: AstraZeneca Pharmaceutical LP :: 1800 Concord Pike :: Wilmington DE 19830-8355 Vapreotide :: Sanvar :: Treatment of symptomatic carcinoid tumors :: 06-04-2004 :: H3 Pharma, Inc. :: 666 Sherbrooke Street West Suite 1400 :: Montreal, Quebec, :: CANADAvapreotide :: Sanvar :: Treatment of esophageal variceal hemorrhage patients with portal hypertension. :: 10-01-2000 :: Debiovision, Inc. :: 666 Sherbrooke Street West :: Suite 1400 :: Montreal, Quebec H3A 1E7 :: CANADAvapreotide :: Octastatin :: Treatment of gastrointestinal and pancreatic fistulas. :: 10-01-2000 :: Debiopharm S.A. :: 17 rue des Terreaux :: CH-1000 Lausanne 9 :: SWITZERLANDvapreotide :: Octastatin :: Prevention of early postoperative complications following pancreatic resection. :: 06-03-2000 :: Debiopharm S.A. :: 17 rue des Terreaux :: CH-1000 Lausanne 9 :: SWITZERLANDvapreotide :: Sanvar :: Treatment of acromegaly :: 04-11-2003 :: H3 Pharma, Inc. :: 666 Sherbrooke Street West, Suite 1400 :: Montreal, Quebec :: varespladib sodium :: Prevention of acute chest syndrome in at-risk patients with sickle cell disease :: 19-11-2007 :: Anthera Pharmaceuticals, Inc. :: 25801 Industrial Blvd. :: Suite B :: Hayward CA 94545 Varicella Zoster Immune Globulin (Human) :: VariZIG :: Passive immunization for the treatment of exposed, susceptible individuals who are at risk of complications from varicella :: 07-11-2006 :: Cangene Corporation :: 155 Innovation Drive :: R3T 5Y3 :: CANADAvascular endothelial growth factor 165b :: Treatment of advanced melanoma stages IIb through IV. :: 24-06-2008 :: PhiloGene, Inc. :: 174 Summit Avenue :: Summit NJ 07901Vasoactive intestinal peptide :: Treatment of Acute Respiratory Distress Syndrome. :: 09-03-2001 :: mondoBIOTECH :: Europark :: Austrasse 79 :: Vasoactive intestinal polypeptide :: Treatment of acute esophageal food impaction. :: 23-06-1993 :: Research Triangle Pharmaceuticals :: 200 Westpark Corporate Center :: 4364 South Alston Avenue :: Durham NC 27713-2280veltuzumab :: Treatment of chronic lymphocytic leukemia :: 28-08-2008 :: Immunomedics, Inc. :: 300 American Road :: Morris Plains NJ 07950Vibriolysin :: Vibrilase :: Debridement of severe, deep dermal burns in hospitalized patients :: 16-06-2006 :: BioMarin Pharmaceutical Inc. :: 105 Digital Drive :: Novato CA 94949vigabatrin :: Sabril :: Treatment of infantile spasms. :: 12-06-2000 :: Ovation Pharmaceuticals, Inc. :: Four Parkway North :: Deerfield IL 60015Viloxazine HCl :: Catatrol :: Treatment of narcolepsy. :: 11-06-1984 :: Stuart Pharmaceuticals :: Division of ICI Americas :: Wilmington DE 19897Viloxazine HCl :: Catatrol :: Treatment of cataplexy. :: 11-06-1984 :: Stuart Pharmaceuticals :: Division of ICI Americas :: Wilmington DE 19897vincristine sulfate liposome injection :: Marqibo :: Treatment of acute lymphoblastic leukemia. :: 08-01-2007 :: Hana Biosciences, Inc. :: 7000 Shoreline Court :: South San Francisco CA 94080vincristine sulfate liposomes :: Marqibo (r) :: Treatment of metastatic uveal melanoma. :: 24-06-2008 :: Hana Biosciences, Inc :: 7000 Shoreline Court :: Suite 370 :: South San Francisco CA 94080 Virulizin :: Virulizin :: Treatment of pancreatic cancer. :: 01-02-2001 :: ZOR Pharmaceuticals, LLC :: 100-A Eastwood Center Drive :: Suite 118 :: Wilmington NC 28403 viscous budesonide :: Treatment for pediatric eosinophilic esophagitis. :: 20-12-2006 :: Meritage Pharma, Inc. :: 12481 High Bluff Drive :: Suite 160 :: San Diego CA 92130 vistonuridine :: An antidote in the treatment of 5-fluorouracil poisoning. :: 01-05-2009 :: Wellstat Therapeutics Corp. :: 930 Clopper Road :: Gaithersburg MD 20878vorinostat :: Treatment of multiple myeloma :: 12-06-2003 :: Merck Research Laboratories :: Merck & Co., Inc. :: P. O. Box 2000, RY 32-605 :: Rahway NJ 07065-0900vorinostat :: Treatment of mesothelioma :: 17-03-2004 :: Merck & Co., Inc. :: P. O. Box 2000, RY 32-605 :: Rahway NJ 07065-0900 Vx-001 :: Treatment of telomerase reverse transcriptase (TERT) positive non-small cell lung cancer in HLA-A*0201 positive patients :: 20-02-2009 :: VAXON-Biotech :: 3-5 impasse Reille :: FRANCEXenogeneic hepatocytes :: HepatAssist Liver Assist System :: Treatment of severe liver failure. :: 27-11-1998 :: Circe Biomedical, Inc. :: 99 Hayden Ave. :: Lexington MA 02421-7995 Yttrium (90Y) antiferritin polyclonal antibodies :: Ferritarg P :: Treatment of Hodgkin's disease. :: 18-09-2006 :: MAT Biopharma :: 4 rue Pierre Fontaine :: FRANCEYttrium-90 radiolabeled humanized monoclonal anti-carcinoembroyonic antigen IgG antibody :: Cea-Cide :: Treatment of ovarian carcinoma. :: 03-08-1999 :: Immunomedics, Inc. :: 300 American Rd. :: Morris Plains NJ 07950Zalcitabine :: Treatment of AIDS. :: 09-12-1986 :: National Cancer Institute, DCT :: NIH, Executive Plaza North, Room 7-18 :: Bethesda MD 20892Zosuquidar trihydrochloride :: Treatment of acute myeloid leukemia :: 15-12-2005 :: Kanisa Pharmaceuticals, Inc. :: 12264 El Camino Real :: San Diego CA 02130

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