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Ode to Not Watching the World Cup
I don't want to overstate this. I don't want to say that by watching World Cup 2022, held in Qatar, on your personal entertainment device, you're stepping over the bodies of dead migrant workers, standing on the heads of incarcerated queer people, and bankrolling, in a tiny but critical way, the global grift. Because we're all compromised, right? We're all implicated. We all live in webs of capit
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2022 SkS Weekly Climate Change & Global Warming News Roundup #47
A chronological listing of news articles posted on the Skeptical Science Facebook Page during the past week: Sun, Nov 13, 2022 thru Sat, Nov 19, 2022. Story of the Week Is COP27 the End of Hopes for Limiting Global Warming to 1.5 Degrees Celsius? The climate talks are going into overtime with little progress toward the emissions cuts required to meet the goals of the Paris Agreement. The COP27 cl
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Sam Bankman-Fried Is Going Down Posting
After losing more than $1 billion of his customers' money, the disgraced crypto titan Sam Bankman-Fried had just one thing to say. "1) What." That inscrutable message, posted on Twitter last weekend, followed a cataclysmic week for the 30-year-old. FTX, the cryptocurrency-trading site he'd founded and turned into a global behemoth, went insolvent. Bankman-Fried's personal wealth plummeted from $1
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So Many People Are Using a Diabetes Drug for Weight Loss That Actual Diabetics Are Having Trouble Getting It
At this point, it's likely that Ozempic has somehow come into your personal zeitgeist. The expensive, name-brand version of semaglutide — which, importantly, was originally developed to manage type 2 diabetes — has been in high demand after going viral on TikTok, where it's picking up a reputation as an effective weight loss aid. "It's the most common medication that I get asked about," Dr. Sudee
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Antigenic sin of wild-type SARS-CoV-2 vaccine shapes poor cross-neutralization of BA.4/5/2.75 subvariants in BA.2 breakthrough infections
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34400-8 Updated vaccines based on Omicron subvariants have started to being rolled out. Analysis of antibody response in individuals with two or three vaccine doses suggests that BA.2 breakthrough infection barely increases cross-neutralization capacity against BA.4/5 or BA.2.75.
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Amazing Map Lets You Scroll Through the Entire Known Universe
All-Encompassing The universe is so vast and old that we can't possibly fathom it all. But we can make some pretty admirable efforts. Take this stunning new map , put together by astronomers at Johns Hopkins University, that displays the entire known universe in all its glory, showcasing some 200,000 galaxies as tiny dots that span all the way to the cosmos' observable limits. Using data gathered
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How people wake up is associated with previous night's sleep together with physical activity and food intake
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34503-2 In a prospective longitudinal study of 833 adults, we demonstrate that how you wake up and regain alertness in the hours after sleep is weakly associated with your genes. Instead, the modifiable factors of how you are sleeping, eating and exercising influence your return to full alertness, free of sleepiness
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A Scary Future of Reading People's Thoughts using Technology
Will all your Secrets get Exposed with Mind Reading Technology? Humans have been pondering the possibility of reading minds for a long time.But will it actually be possible in the future? Will mind-reading technology bring an end to our privacy once and for all? let's take a look Check out this video to get an overview👇 https://youtu.be/j8RGm7VK_lw Whenever we think something, there is electrica
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Behind the Lawsuit Against Celebs Who Shilled FTX Before Its Spectacular Meltdown
Above all else, FTX advertisements wanted you to know two things: that cryptocurrency is a force for good, and that you don't need to be an expert to buy and trade it. In fact, you don't even have to understand it at all. You just need to get involved, because if you don't, you'll get left behind. If a bit cheesy then, those same promotions — an array of of television commercials, social media po
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Experts Excoriate NASA Report Claiming James Webb Wasn't Homophobic
NASA says it can't find any record that James Webb, the State Department and NASA leader for whom the agency's groundbreaking new space telescope is named, was aware of homophobic government purges — but a bunch of astronomers are clapping back at the agency's claims. "After an exhaustive search of U.S. government and Truman library archives," administrator Bill Nelson was quoted as saying in the
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Photocatalytic direct borylation of carboxylic acids
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34833-1 Boronic acids are useful reagents in organic synthesis and thus methods to prepare these compounds under mild conditions are desirable. Here, the authors synthesize boronic acids via photocatalytic decarboxylation of benzoic acids followed by borylation; guanidine-type additives are used to assist the proces
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PEAR1 regulates expansion of activated fibroblasts and deposition of extracellular matrix in pulmonary fibrosis
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34870-w Currently, there is a lack of effective drugs for the treatment of pulmonary fibrosis. Here, the authors reveal a novel role of PEAR1 in fibroblast activation and demonstrate that activating PEAR1 by monoclonal antibodies might be a promising therapeutic approach for pulmonary fibrosis.
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Structure of the human heparan sulfate polymerase complex EXT1-EXT2
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34882-6 Heparan sulfates are long and complex polysaccharides that mediate a large number of biological processes at the cell surface. Here, the authors provide structural and functional insights into the human EXT1-EXT2 complex that carries out the polymerization of heparan sulfate chains.
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This Week's Awesome Tech Stories From Around the Web (Through November 19)
FUTURE Picture Limitless Creativity at Your Fingertips Kevin Kelly | Wired "For the first time in history, humans can conjure up everyday acts of creativity on demand, in real time, at scale, for cheap. Synthetic creativity is a commodity now. Ancient philosophers will turn in their graves, but it turns out that to make creativity—to generate something new—all you need is the right code. We can i
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$500K Haul for Parker! A Season's Worth of Gold in a Week! | Gold Rush
Stream Gold Rush on discovery+: https://www.discoveryplus.com/show/gold-rush #GoldRush #Discovery #discoveryplus Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Follow Us on TikTok: https://www.tiktok.com/@Discovery We're on Instagram! https://instagram.com/Discovery Join Us on Facebook: https://www.facebook.com/Discovery Follow Us on Twitter: https://twitter.com/Discovery From: Discover
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Whose Midlife Crisis Is It, Anyway?
The television series Fleishman Is in Trouble begins upside down, with the camera soaring over an inverted Manhattan skyline—squat brick buildings in the top half of the frame, hazy blue sky below. It's an appropriately destabilizing introduction for a show that's constantly pulling the rug out from underneath us. The series is untrustworthy, in the best kind of way: It withholds and obscures and
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Why We Eat Together
This is an edition of The Wonder Reader, a newsletter in which our editors recommend a set of stories to spark your curiosity and fill you with delight. Sign up here to get it every Saturday morning. For human beings, a meal is never just a meal, and a snack is never just a snack. As the writer and scientist Louise O. Fresco noted in The Atlantic in 2015, "Even where a lonely diner picks sweets o
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Tár Has an Answer to Art's Toughest Question
This story contains major spoilers for Tár . As someone who writes about art and artists for a living, I confess that I find no question more exhausting than "Can we separate the art from the artist?" The only good answer is a frustrating one: "It depends." So I went into Tár , Todd Field's acclaimed movie starring Cate Blanchett, with some dread. The film, which follows a fictional famed classic
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The Qatar World Cup Exposes Soccer's Shame
Qatar hosting the soccer World Cup is like Donald Trump becoming president of the United States. It should not have happened, but the very fact that it has only exposes how bad things have become. Once this famous old tournament kicks off in Doha tomorrow, the fact that it did can never be unwound: Qatar will forever have been the host of the 22nd FIFA World Cup, the greatest absurdity in the his
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How Carvedilol activates β2-adrenoceptors
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34765-w How carvedilol, a β1-blocker, activates β2-adrenoceptors, is unclear. Here, the authors resolve this enigma and show that carvedilol drives all of its detectable cellular β2-adrenoceptor signals by slow and low efficacy G protein activation.
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Bruce Springsteen's Misguided Homage
What is it about reaching their 70s that makes great songwriters want to sing old songs they didn't write? Paul McCartney reached backwards to pre-Beatles music and released an album of mostly Tin Pan Alley ditties, slipping in a couple of originals in the same style, in 2012, the year he turned 70. Bob Dylan took up crooning vintage standards associated with Frank Sinatra for the first of severa
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Radio Atlantic: For Love of the Game
Part of the appeal of the World Cup is watching countries' finest soccer players represent their nations. For many fans, though, it doesn't have to just be root-root-root for the home team. The Atlantic staff writer Clint Smith will be cheering for the U.S., but he will also have his eye on Senegal. Smith's attachment to the game is personal, stretching back to when he first started soccer playin
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Charge-separation driven mechanism via acylium ion intermediate migration during catalytic carbonylation in mordenite zeolite
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34708-5 The tremendous application of carbonylation reaction requires the elaborate explanation to reaction mechanism. Here the authors propose a charge-separation driven mechanism of methyl acetate formation via acylium ion intermediate in mordenite zeolite by an integrated reaction/diffusion kinetics model during
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Weekend reads: 'Illegal practices in palaeontology'; 'a fake badge of integrity'; researcher jailed
Would you consider a donation to support Weekend Reads, and our daily work? Thanks in advance. The week at Retraction Watch featured: Our list of retracted or withdrawn COVID-19 papers is up to 270. There are more than 36,000 retractions in our database — which powers retraction alerts in EndNote, LibKey, Papers, and Zotero. And have you seen our leaderboard of authors with the most … Continue rea
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Structural and functional asymmetry of RING trimerization controls priming and extension events in TRIM5α autoubiquitylation
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34920-3 TRIM5α is an E3 ligase that inhibits retroviral replication. Here, the authors delineate the biochemical mechanism that accelerates N terminal autoubiquitylation of TRIM5α upon its association with the retroviral capsid and, thus, enables recognition of an infection-associated molecular pattern.
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Does exposure to cold and flu viruses weaken or strengthen the immune system?
And is that answer different now in our Covid world? Linda Geddes looks at the evidence and talks to the experts As temperatures drop and November rain falls, the seasonal onslaught of coughs, sore throats and sniffles may feel inevitable, but does constant exposure to everyday infections such as colds or influenza drain us or make us stronger? Our immune systems are often said to have memory, me
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Melting of generalized Wigner crystals in transition metal dichalcogenide heterobilayer Moiré systems
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34683-x Recent experiments on a WSe2/WS2 hetero-bilayer detected incompressible charge ordered states considered to be generalized Wigner crystals. Here, by performing Monte Carlo simulations of a triangular moiré lattice, the authors study the phases which emerge on melting such charge-ordered states in partially f
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Disparate impacts on online information access during the Covid-19 pandemic
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34592-z The COVID-19 pandemic has stimulated an important changes in online information access. Here, the authors analyse everyday web search interactions across 25,150 US ZIP codes revealing significant differences in how digital informational resources are mobilized by different communities.
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Continuous resin refilling and hydrogen bond synergistically assisted 3D structural color printing
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34866-6 3D photonic crystals (PCs) attract attention due to their unique optical properties but printing of colloidal particles is limited by lack of control over the assembly. Here, the authors demonstrate a continuous digital light processing 3D printing strategy using hydrogen bond assisted colloidal inks for fab
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Imperceptible, designable, and scalable braided electronic cord
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34918-x Inspired by the characteristics of textile-based flexible electronic sensors, the authors report a braided electronic cord with a low-cost, and automated fabrication to realize imperceptible, designable, and scalable user interfaces with the features of user-friendliness, excellent durability and rich intera
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Mutant RIG-I enhances cancer-related inflammation through activation of circRIG-I signaling
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34885-3 By recognizing double-stranded RNA, RIG-I is implicated in anti-viral immune responses, but also in cancer development and intestinal inflammation. Here the authors identify frameshift germline mutations of RIG-I, resulting in the generation of a circular RNA associated with increased susceptibility to colit
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Onboard early detection and mitigation of lithium plating in fast-charging batteries
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-33486-4 Fast-charging is highly desired for lithium-ion batteries but is hindered by potential hazardous lithium plating and the associated parasitic reactions. Here, the authors report a nondestructive differential pressure sensing method for early detection and mitigation of lithium plating in fast-charging batter
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Feedback between mechanosensitive signaling and active forces governs endothelial junction integrity
Nature Communications, Published online: 19 November 2022; doi:10.1038/s41467-022-34701-y Gap formation in the vasculature underpins immune and tumour cell infiltration. Here the authors propose a chemo-mechanical model to analyse how feedback between mechanosensitive signalling, active cellular forces and adhesion governs the breakdown, recovery, and integrity of endothelial junctions.
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Toxins force construction of 'roads to nowhere'
Toxins released by a type of bacteria that cause diarrheal disease hijack cell processes and force important proteins to assemble into 'roads to nowhere,' redirecting the proteins away from other jobs that are key to proper cell function, a new study has found.
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The Harvard Business School Professor Who Isn't Counting Elon Musk Out
In the weeks since Elon Musk took over as CEO of Twitter, the company has laid off nearly half of its workers and offered the remaining employees an ultimatum: Commit to being "extremely hardcore" going forward or leave the company . According to The New York Times , hundreds of employees have opted for the latter. On Wednesday night—as the deadline loomed—Andy Wu, an assistant professor of busin
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Democracy's Dunkirk
This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. Sign up for it here . The authoritarians at home and abroad have faced some reversals, but Americans should consider the midterm elections as only a respite. Liberal democracy remains in danger in the United States and aro
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Toxins force construction of 'roads to nowhere'
Toxins released by a type of bacteria that cause diarrheal disease hijack cell processes and force important proteins to assemble into "roads to nowhere," redirecting the proteins away from other jobs that are key to proper cell function, a new study has found.
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The tilt in our stars: The shape of the Milky Way's halo of stars is realized
A new study has revealed the true shape of the diffuse cloud of stars surrounding the disk of our galaxy. For decades, astronomers have thought that this cloud of stars—called the stellar halo—was largely spherical, like a beach ball. Now a new model based on modern observations shows the stellar halo is oblong and tilted, much like a football that has just been kicked.
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Elizabeth Holmes Sentenced to More Than 11 Years in Prison for Theranos Fraud
A few short years ago, media reports were holding up Theranos founder and CEO Elizabeth Holmes as the next Steve Jobs, a comparison she clearly invited with her trademark black turtleneck and deep speaking voice. However, the company's supposedly revolutionary blood testing technology didn't work, and Holmes now stands convicted of multiple counts of wire fraud. After numerous delays due to the C
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An enantioselective four-component reaction via assembling two reaction intermediates
Nature Communications, Published online: 18 November 2022; doi:10.1038/s41467-022-34913-2 The interception of one chemical intermediate with another intermediate is very challenging, as intermediates may be incompatible or too reactive, but could result in a streamlined method of organic synthesis. Here, the authors demonstrate enantioselective four-component reactions via the coupling of two int
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Twitter Claims Video of Moon Rocket Launch Is Revenge Porn
Nice Rocket Revenge porn is a horrible thing , and Twitter should definitely continue to ban anyone who attempts to post it on the app. That being said, a video of a rocket taking off — an actual rocket, you pervs — does not revenge porn make, and shouldn't be flagged as such. It seems like a silly thing to have to say, but such is the exact situation that spaceflight photographer John Kraus foun
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A Tale of Terroir: Porcini mushrooms have evolved with a preference to local adaptation
A genetic survey of porcini mushrooms across the Northern Hemisphere found that these delicious fungi evolved in surprising ways — contrary to the expectations of many who think that geographic isolation would be the primary driver for species diversity. In fact, there are regions in the world where porcini maintain their genetic distinctiveness in local ecological niches, even if they are not is
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How Taylor Swift Broke Ticketmaster
Make no mistake: Ticketmaster deserves the scorn that it is currently receiving from Taylor Swift's listenership, a population of such size and power that it probably merits a spot in the United Nations. Earlier this week, the company's just-for-fans presale of tickets to Swift's 2023 concert tour was riddled with bugs and delays. More shocking, Ticketmaster then canceled the general-public sale
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Inducing hibernation-like state in mice can protect organs during heart surgery
Researchers have developed a new method of protecting organs during heart and aortic surgery when blood circulation has to be blocked. Rather than relying on cold temperatures to induce hypometabolism and reduce the need for oxygen, the technique works by stimulating Q neurons in the brain, which slows metabolism down to a hibernation-like state. The findings could lead to new ways of performing s
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NASA Tells Astronauts That Tweeting Isn't As Important as Staying Alive
Stayin' Alive NASA's astronaut social media handbook just dropped — and they've got some staunch guidelines for space tweeting. As part of a public records request, NASA released to Vox an almost entirely unredacted copy of its current social media handbook for astronauts , and it offers a fascinating look into the agency's policies for the online astronauts it sends to space. Overall, it's a rea
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Elon Musk Locks Twitter Employees Out Office, Then Asks Them to Meet Him on the 10th Floor
Worst Case Scenario Elon Musk's Twitter-buying experiment is somehow going even worse than expected, amid reports that he's locked employees out of the company's office buildings. As reported by Platformer 's Zoë Schiffer , an email sent to Twitter staff yesterday evening informed them out of the blue that they wouldn't be able to get into their offices for the rest of the week. "We're hearing th
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Accessing chiral sulfones bearing quaternary carbon stereocenters via photoinduced radical sulfur dioxide insertion and Truce–Smiles rearrangement
Nature Communications, Published online: 18 November 2022; doi:10.1038/s41467-022-34836-y The preparation of chiral sulfones featuring quaternary carbon stereocenters remains challenging. Here the authors report the synthesis of such compounds via a multicomponent reaction involving a photoinduced radical sulfur dioxide insertion followed by an asymmetric Truce–Smiles rearrangement.
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CLEC-1 is a death sensor that limits antigen cross-presentation by dendritic cells and represents a target for cancer immunotherapy | Science Advances
Abstract Tumors exploit numerous immune checkpoints, including those deployed by myeloid cells to curtail antitumor immunity. Here, we show that the C-type lectin receptor CLEC-1 expressed by myeloid cells senses dead cells killed by programmed necrosis. Moreover, we identified Tripartite Motif Containing 21 (TRIM21) as an endogenous ligand overexpressed in various cancers. We observed that the c
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First field evidence of the electrical multipolar nature of volcanic aggregates | Science Advances
Abstract The description of the formation of ash aggregates is crucial to our understanding of tephra dispersal and, therefore, to the forecasting of volcanic ash concentration in the atmosphere. Regardless of the importance of electrostatic processes, particle and aggregate charge is of complex determination both in the field and in the laboratory. We have measured the bulk charge carried by sin
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Unified epigenomic, transcriptomic, proteomic, and metabolomic taxonomy of Alzheimer's disease progression and heterogeneity | Science Advances
Abstract Alzheimer's disease (AD) is a heterogeneous disorder with abnormalities in multiple biological domains. In an advanced machine learning analysis of postmortem brain and in vivo blood multi-omics molecular data ( N = 1863), we integrated epigenomic, transcriptomic, proteomic, and metabolomic profiles into a multilevel biological AD taxonomy. We obtained a personalized multilevel molecular
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A balance of noncanonical Semaphorin signaling from the cerebrospinal fluid regulates apical cell dynamics during corticogenesis | Science Advances
Abstract During corticogenesis, dynamic regulation of apical adhesion is fundamental to generate correct numbers and cell identities. While radial glial cells (RGCs) maintain basal and apical anchors, basal progenitors and neurons detach and settle at distal positions from the apical border. Whether diffusible signals delivered from the cerebrospinal fluid (CSF) contribute to the regulation of ap
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A unified approach and descriptor for the thermal expansion of two-dimensional transition metal dichalcogenide monolayers | Science Advances
Abstract Two-dimensional (2D) materials have enabled promising applications in modern miniaturized devices. However, device operation may lead to substantial temperature rise and thermal stress, resulting in device failure. To address such thermal challenges, the thermal expansion coefficient (TEC) needs to be well understood. Here, we characterize the in-plane TECs of transition metal dichalcoge
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Diabetic hyperglycemia promotes primary tumor progression through glycation-induced tumor extracellular matrix stiffening | Science Advances
Abstract Diabetes mellitus is a complex metabolic disorder that is associated with an increased risk of breast cancer. Despite this correlation, the interplay between tumor progression and diabetes, particularly with regard to stiffening of the extracellular matrix, is still mechanistically unclear. Here, we established a murine model where hyperglycemia was induced before breast tumor developmen
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Flies trade off stability and performance via adaptive compensation to wing damage | Science Advances
Abstract Physical injury often impairs mobility, which can have dire consequences for survival in animals. Revealing mechanisms of robust biological intelligence to prevent system failure can provide critical insights into how complex brains generate adaptive movement and inspiration to design fault-tolerant robots. For flying animals, physical injury to a wing can have severe consequences, as fl
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Rapid marine oxygen variability: Driver of the Late Ordovician mass extinction | Science Advances
Abstract The timing and connections between global cooling, marine redox conditions, and biotic turnover are underconstrained for the Late Ordovician. The second most severe mass extinction occurred at the end of the Ordovician period, resulting in ~85% loss of marine species between two extinction pulses. As the only "Big 5" extinction that occurred during icehouse conditions, this interval is a
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Genetic slippage after sex maintains diversity for parasite resistance in a natural host population | Science Advances
Abstract Although parasite-mediated selection is a major driver of host evolution, its influence on genetic variation for parasite resistance is not yet well understood. We monitored resistance in a large population of the planktonic crustacean Daphnia magna over 8 years, as it underwent yearly epidemics of the bacterial pathogen Pasteuria ramosa . We observed cyclic dynamics of resistance: Resis
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Spatially targeted brain cancer immunotherapy with closed-loop controlled focused ultrasound and immune checkpoint blockade | Science Advances
Abstract Despite the challenges in treating glioblastomas (GBMs) with immune adjuvants, increasing evidence suggests that targeting the immune cells within the tumor microenvironment (TME) can lead to improved responses. Here, we present a closed-loop controlled, microbubble-enhanced focused ultrasound (MB-FUS) system and test its abilities to safely and effectively treat GBMs using immune checkp
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Chiroptical activity of gas-phase propylene oxide predicting the handedness of interstellar circular polarization in the presolar nebula | Science Advances
Abstract Propylene oxide, the first chiral molecule recently detected in the interstellar medium, has once again raised the question whether biomolecular chirality might have cosmic origins. However, accurate chiroptical properties of propylene oxide in the ultraviolet spectral range necessary to suggest possible asymmetric synthetic routes in the gas phase are scarce. Here, we report on the firs
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Nonstop mRNAs generate a ground state of mitochondrial gene expression noise | Science Advances
Abstract A stop codon within the mRNA facilitates coordinated termination of protein synthesis, releasing the nascent polypeptide from the ribosome. This essential step in gene expression is impeded with transcripts lacking a stop codon, generating nonstop ribosome complexes. Here, we use deep sequencing to investigate sources of nonstop mRNAs generated from the human mitochondrial genome. We ide
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Articular fibrocartilage-targeted therapy by microtubule stabilization | Science Advances
Abstract The fibrocartilage presented on the joint surface was caused by cartilage injury or degeneration. There is still a lack of effective strategies for fibrocartilage. Here, we hypothesized that the fibrocartilage could be viewed as a raw material for the renewal of hyaline cartilage and proposed a previously unidentified strategy of cartilage regeneration, namely, "fibrocartilage hyalinizat
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SARS-CoV-2 Omicron BA.1 and BA.2 are attenuated in rhesus macaques as compared to Delta | Science Advances
Abstract Since the emergence of SARS-CoV-2, five different variants of concern (VOCs) have been identified: Alpha, Beta, Gamma, Delta, and Omicron. Because of confounding factors in the human population, such as preexisting immunity, comparing severity of disease caused by different VOCs is challenging. Here, we investigate disease progression in the rhesus macaque model upon inoculation with the
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A bistable and reconfigurable molecular system with encodable bonds | Science Advances
Abstract Molecular systems with ability to controllably transform between different conformations play pivotal roles in regulating biochemical functions. Here, we report the design of a bistable DNA origami four-way junction (DOJ) molecular system that adopts two distinct stable conformations with controllable reconfigurability by using conformation-controlled base stacking. Exquisite control ove
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How '2D' materials expand
Researchers developed a technique to effectively measure the thermal expansion coefficient of two-dimensional materials. With this information, engineers could more effectively and efficiently use these atomically-thin materials to develop next-generation electronic devices that can perform better and run faster than those built with conventional materials.
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'Butterfly bot' is fastest swimming soft robot yet
Inspired by the biomechanics of the manta ray, researchers have developed an energy-efficient soft robot that can swim more than four times faster than previous swimming soft robots. The robots are called 'butterfly bots,' because their swimming motion resembles the way a person's arms move when they are swimming the butterfly stroke.
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Ticketmaster May Have Finally Met Its Match: Furious Swifties
The notorious ticket peddling service Ticketmaster has never been a fan favorite, and anyone who's ever bought a concert ticket there can attest to why. Preposterous prices, slimy junk fees, and terrible customer service are just a few of its mundane evils. In spite of how universally reviled it is, Ticketmaster has persisted as the king of the box office. But now, it's facing its worst PR nightm
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Clinical trials often exclude people with intellectual disabilities
, a new study shows. Scientific breakthroughs aren't possible without the painstaking process of clinical trials. So what happens when many of those trials leave out large portions of the population? Katherine McDonald, a professor of public health at Syracuse University, and associate dean of research in the Falk College of Sport and Human Dynamics, focuses her research around the theme of creat
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Rare liver cancer is 'addicted' to 1 specific gene mutation
A new study shows that a rare kind of liver tumor needs one specific mutation in order to thrive, and that impeding the mutated oncogene reduces tumor growth in mice. Fibrolamellar carcinoma is a rare and lethal liver cancer that disproportionately harms young adults. It is nearly incurable. Surgery can remove the tumor, but no existing therapies are capable of reining in the cancer once it start
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Do not adjust your clock: scientists call time on the leap second
Second added periodically to synchronise atomic time and Earth time can cause problems for GPS systems, software and telecoms Scientists and government representatives meeting at a conference in France have voted to scrap leap seconds by 2035, the organisation responsible for global timekeeping has said. Similar to leap years, leap seconds have been periodically added to clocks over the last half
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How Close Are We to Nuclear War?
On Tuesday, a missile landed in Przewodów, a Polish village near the border with Ukraine. Two people were killed in the blast. Their deaths were a direct consequence of Russia's ongoing invasion of Ukraine, though in the fog of war it was not immediately clear which side was to blame. Initial theories held that the missile had been fired by Russia at Ukraine and gone astray, though later U.S. int
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Bacteria sensors report when they find chemical invaders
Researchers have engineered bacteria to quickly sense and report on the presence of a variety of contaminants in the environment. Their study in Nature shows the cells can be programmed to identify chemical invaders and report within minutes by releasing a detectable electrical current. Such "smart" devices could power themselves by scavenging energy in the environment as they monitor conditions
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NASA Orders Press Not to Photograph Launch Site After Moon Mission Takes Off
No Photos, Please NASA barred the press from photographing the launch site of its Space Launch System after it boosted the agency's Artemis I Moon mission into space earlier this week. Multiple space reporters said on Twitter that the agency had sent them a message telling them they were prohibited from photographing the Artemis 1 launch tower after the liftoff. "NASA did not provide a reason," E
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Earth weighs in at six ronnagrams as new prefixes picked for big and small
Ronna, quetta, ronto and quecto added to International System of Units in first such change for more than 30 years Experts have voted for an expansion of the universe – or at least the official terminology that can be drawn upon to describe the vanishingly small and the preposterously large. In a vote at the General Conference on Weights and Measures in Versailles on Friday, the International Sys
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Researchers discover Egypt's oldest tomb oriented to winter solstice
Researchers of the University of Malaga (UMA) and the University of Jaen (UJA) have discovered Egypt's oldest tomb oriented to the winter solstice. Located in the necropolis of Qubbet el-Hawa (Aswan), it is precisely oriented to the sunrise of the winter solstice, in such a way that the sun's rays bathed with its light the place that was intended to house the statue of a governor of the city of El
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Looking at oxygen storage dynamics in three-way catalysts
In light of vehicular pollutants contributing to decreasing air quality, governments across the globe are posing stricter emission regulations for automobiles. This calls for the development of more efficient exhaust gas after-treatment systems, which are systems to "clean" exhaust gas before it is released into the atmosphere).
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Scientists develop new fertilizer from food chain waste
Researchers from the Università Cattolica at Piacenza, have developed a new fertilizer from food chain waste, specifically from the waste of the productions of lactic acid bacteria that currently have to be eliminated through purification processes.
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Novel AI blood test detects liver cancer
A novel artificial intelligence blood testing technology has been used to successfully detect lung cancer in a 2021 study has now detected more than 80% of liver cancers in a new study of 724 people.
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Scientists build nanoscale parapets, aqueducts, and other shapes
Scientists have developed a new way to guide the self-assembly of a wide range of novel nanoscale structures using simple layered block copolymers as starting materials. The work could help guide the design of custom surface coatings with tailored optical, electronic, and mechanical properties for use in sensors, batteries, filters, and more.
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Legacy of a molecular dynamics trailblazer
Physicists explains how the theoretical chemist Martin Karplus and his team applied the approach of molecular dynamics simulation to a large biological molecule, a protein, deeply impacting biology and the physical sciences in the 20th and 21st centuries.
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Engineers solve a mystery on the path to smaller, lighter batteries
A new discovery could finally usher the development of solid-state lithium batteries, which would be more lightweight, compact, and safe than current lithium batteries. The growth of metallic filaments called dendrites within the solid electrolyte has been a longstanding obstacle, but the new study explains how dendrites form and how to divert them.
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How well do state-of-the-art climate models simulate sea level?
According to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change, the global mean sea level has risen faster since 1900 than over any preceding century in the last 3000 years. This makes hundreds of coastal cities and millions of people vulnerable to a threat of higher water levels.
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Researchers develop a novel integration scheme for efficient coupling between III-V and silicon
Researchers at the Hong Kong University of Science and Technology (HKUST) has recently developed a novel integration scheme for efficient coupling between III-V compound semiconductor devices and silicon components on silicon photonics (Si-photonics) platform by selective direct epitaxy, unlocking the potential of integrating energy-efficient photonics with cost-effective electronics, as well as e
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Honey bees prosper with quality, not quantity, of food in novel laboratory setup
Honey bee workers collect pollen and nectar from a variety of flowering plants to use as a food source. Honey bees typically forage from up to 1-2 miles away from the hive, though sometimes they travel even further, including up to 10 miles away. However, much of the modern landscape consists of agricultural fields, which limits the foraging options for honey bees in these areas.
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Save the economy, save the planet, says sustainability expert
A new book by UVM economist Jon Erickson, "The Progress Illusion: Reclaiming Our Future from the Fairytale of Economics" (Island Press, Dec. 1) explores the harsh economic realities that have led to sky-high inflation, growing inequality, polarized politics, and climate crisis.
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Food marketing and research on kids lacks government oversight
Federal regulations ban tobacco companies from advertising to kids and prohibit profanity on television before 10 p.m. But what is protecting children from predatory advertising of junk food, especially with sneaky online marketing tactics like the use of influencers?
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Opinion: Tackling the climate crisis beyond COP
The clock is ticking. The 27th United Nations Framework Convention on Climate Change (UNFCCC) Conference of the Parties (COP27) is nearly halfway through. Beyond the nice words, some announcements designed to make headlines and more explanations about how bad the climate crisis is, COP27's outputs and results are far from what the world expects and what the planet needs.
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Honey bees prosper with quality, not quantity, of food in novel laboratory setup
Honey bee workers collect pollen and nectar from a variety of flowering plants to use as a food source. Honey bees typically forage from up to 1-2 miles away from the hive, though sometimes they travel even further, including up to 10 miles away. However, much of the modern landscape consists of agricultural fields, which limits the foraging options for honey bees in these areas.
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Wyze Scale X review
The Wyze Scale X is an affordable and well-designed smart scale that can easily track your health and fitness.
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NASA Drops Stunning New James Webb Image of a Star Being Born
Birth Canal The James Webb Space Telescope's latest mind-bending image just dropped — and this one is, in a word, splendid. As NASA notes in a blog post about the finding, the telescope's Near-Infrared Camera (NIRCam) was put to incredible use when capturing the "once-hidden features" of the beginnings of a star. Known as "protostars," celestial objects like this one — found inside an uber-absorb
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