Pancake/flatbread with a 'nutty' taste is first evidence of complex cooking and food culture If you thought Neanderthals survived on a diet of foraged berries and uncooked animal flesh, think again. Charred remnants of what appear be the world's oldest cooked meal ever found have been unearthed in a cave complex in northern Iraq, prompting speculation that Neanderthals may have been foodies. "Our
If you see a great bustard (Otis tarda) in the wild, you're unlikely to forget it. Massive, colorful, and impossible to mistake, they are the heaviest birds living today capable of flight, with the greatest size difference between the sexes. They are also "lek breeders," where males gather at chosen sites to put on an audiovisual show for the visiting females, who choose a mate based on his appear
My brother arrived in my life like the rain always did: after fervent prayer and petitioning. My father was a crop duster in the Texas Panhandle, a land where memories of the Dust Bowl remained painfully fresh even as the farmers remained stubbornly persistent. And so we were always praying for rain, before Friday-night high-school football games, around the dinner table, at church on Sunday morn
This is today's edition of The Download , our weekday newsletter that provides a daily dose of what's going on in the world of technology. Meta's game-playing AI can make and break alliances like a human Meta has created an AI that can beat humans at an online version of Diplomacy, a popular strategy game in which seven players compete for control of Europe by moving pieces around on a map. Unlik
Supermassive black holes that beam powerful jets of matter towards Earth, known as blazars, accelerate particles to extraordinarily high energies – and astronomers have finally figured out how
Physicists at the University of Basel have experimentally demonstrated for the first time that there is a negative correlation between the two spins of an entangled pair of electrons from a superconductor. For their study, the researchers used spin filters made of nanomagnets and quantum dots, as they report in the scientific journal Nature.
A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.
A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.
Hackathon In the hours after the FTX cryptocurrency exchange filed for bankruptcy, opportunistic hackers — or possibly an insider — took advantage of the chaos and began looting hundreds of millions of dollars worth of crypto. Now, it appears, they're hard at work laundering it. As CNBC reports , the exchange's new CEO, John Ray III, admitted when the company filed for bankruptcy earlier in the m
Nature, Published online: 23 November 2022; doi:10.1038/d41586-022-04122-4 The ExoMars programme was imperilled after the European Space Agency cut ties with its former partner Russia.
Scientists looking to understand the fundamental brain mechanisms of autism spectrum disorder have found that a gene mutation known to be associated with the disorder causes an overstimulation of brain cells far greater than that seen in neuronal cells without the mutation. The study, spanning seven years, employed some of the most advanced approaches available in the scientific toolbox, including
Bringing transparency to how a vaccine becomes a vaccine, Dr. Jen Gunter breaks down research, development and testing that makes these life-saving therapeutics safe — long before they reach your local pharmacy. For more on how your body works, tune in weekly to her podcast Body Stuff with Dr. Jen Gunter, from the TED Audio Collective.
In the Northern Hemisphere, this year's winter hasn't yet begun. But Melissa J. Sacco, a pediatric-intensive-care specialist at UVA Health, is already dreading the arrival of the one that could follow. For months, the ICU where Sacco works has been overflowing with children amid an early-arriving surge of respiratory infections. Across the country, viruses such as RSV and flu, once brought to nea
There was a moment a few years ago when I couldn't help but cringe a little every time I heard the word story , so wantonly was it being bandied about. This was during the Trump administration, when lots of people still sweetly believed that culture could counter raw political power, that protest art could engender a sense of shame among the shameless, even that satire might have the capacity to
With Black Friday and Cyber Monday upon us, Rutgers University experts weigh in on the holiday retail season, including how you can save money while focusing on holiday cheer: The post appeared first on Futurity .
New research charts the radical evolutionary changes to the thigh bones of dinosaurs and birds that allowed them to stand on two feet. The findings resolve a longstanding question about dinosaur evolution and offer a prime example of how new physical features can pop up briefly during embryonic development and then give way to older, known features in adults. The new study shows how changes in th
Mathematicians love a good puzzle. Even something as abstract as multiplying matrices (two-dimensional tables of numbers) can feel like a game when you try to find the most efficient way to do it. It's a little like trying to solve a Rubik's Cube in as few moves as possible — challenging, but alluring. Except that for a Rubik's Cube, the number of possible moves at each step is 18… Source
What could be one of Norway's oldest shipwrecks has been found on the bottom of a lake near Oslo, during an effort to locate the tons of unexploded ammunition dumped there since World War II.
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
A recent study has discovered and characterized secreted proteins from the pathogen Candidatus Liberibacter solanacearum. These proteins, called effectors, offer clues into the manipulation tactics this bacterium uses to subdue its plant host. The study found that these effectors can be present in both the plant and insect host.
An ambitious plan to sequence the genomes of all known species of euglenoids over the next decade has been launched. The network of scientists behind the initiative believe it has the potential to drive breakthroughs ranging from new biofuels and sustainable foods to cancer medicines.
Researchers have found that administering remdesivir with corticosteroids to Asian patients who are critically ill with COVID-19 within 9 days of symptom onset reduces overall mortality. Starting treatment later did not have the same effect, suggesting that higher viral loads and serious lung damage impair the effectiveness of this treatment.
Scientists have produced a proof of concept for a new and better way of caring for women facing the life-threatening situation of ectopic pregnancy, which occurs when a fertilized egg implants somewhere other than the lining of the uterus.
The holiday season is filled with hearty, delicious food, visiting with friends and family, decreased physical activity, busy schedules and weight gain. According to a Kansas State University veterinarian, it is also a time for our family pets to gain weight as well.
I have been writing a lot recently about global warming and energy infrastructure. This is partly because there is a lot of news coming out of COP27, but also because both here and on the SGU there has been some lively and informative discussion on the issue. Also, this is a very complex issue and as people raise new points it sends me down different rabbit holes of information. I am trying to de
The holiday season is filled with hearty, delicious food, visiting with friends and family, decreased physical activity, busy schedules and weight gain. According to a Kansas State University veterinarian, it is also a time for our family pets to gain weight as well.
Thanksgiving may be right around the corner, but Maine's wild turkeys have more to worry about than ending up on the kitchen table. Winter is coming, and with it, extremely cold temperatures and fewer resources for turkeys to thrive. According to a University of Maine study, wild turkeys will adjust their movements in inclement winter weather to increase their odds of survival, but their behaviors
Submerged below the waves of the English Channel lies an important scientific record of undiscovered Neanderthal artifacts dating back to the last ice age. Collecting them from beneath the channel's cold waters is no easy feat, but UCL researchers found a way to get a brief peek at the otherwise hidden landscape.
The early 2020s have been a chaotic time, with seemingly one crisis after another befalling humanity: the Covid-19 pandemic, inflation and supply chain upheaval, political instability and extremism, climate change…the list goes on. But what does it all really mean, or matter, when you zoom out and look at the big picture? An astronomy professor from Johns Hopkins University has given us the chanc
An ambitious plan to sequence the genomes of all known species of euglenoids over the next decade has been launched. The network of scientists behind the initiative believe it has the potential to drive breakthroughs ranging from new biofuels and sustainable foods to cancer medicines.
New research demonstrates that certain chemical coatings, applied to micro/nanoparticles, can alter their swimming propulsion within biological fluids.
Thanksgiving may be right around the corner, but Maine's wild turkeys have more to worry about than ending up on the kitchen table. Winter is coming, and with it, extremely cold temperatures and fewer resources for turkeys to thrive. According to a University of Maine study, wild turkeys will adjust their movements in inclement winter weather to increase their odds of survival, but their behaviors
Nature, Published online: 23 November 2022; doi:10.1038/d41586-022-03767-5 Structural insights into a long-studied folate-transport protein provide evidence that might lead to entirely new targeted anticancer treatments, or boost the success of immunotherapy approaches to tackling tumours.
Nature, Published online: 21 November 2022; doi:10.1038/d41586-022-03774-6 People in the United States tend to associate with others who hold views that are similar to their own — but more radical.
Virtual 3D tours on real estate websites, such as Zillow and Redfin, could pose privacy risks to the current residents. Sometimes the homes in these tours are staged, but other times they contain evidence of current residents' lives. University of Washington researchers were curious about whether personal belongings visible in 3D tours could introduce privacy risks. The team examined 44 3D tours
There is a less obvious source of carbon emissions than cars and factories: rivers and streams. Inland waters release carbon in the atmosphere, but their contributions depend on their concentration of dissolved inorganic carbon (DIC) from minerals and other sources. But what factors impact DIC concentrations? A team of Penn State engineers has now determined that both water discharge—or the volume
Three currently circulating omicron subvariants of SARS-CoV-2 are better at evading vaccine- and infection-generated neutralizing antibodies than earlier versions of omicron, new research suggests.
New research demonstrates that certain chemical coatings, applied to micro/nanoparticles, can alter their swimming propulsion within biological fluids.
På bagkant af amputationssagen bør vi diskutere variation i sundhedsvæsenet. For er variation i sundhedsvæsenets behandling og resultater altid et problem, eller er variation faktisk grundlaget for læring og udvikling? Efter amputationssagen er der behov for at få en nuanceret debat om variation i sundhedsvæsenet og at variation også er en mulighed for læring og udvikling.
Professor på Center for Almen Medicin på Københavns Universitet, Lars Bjerrum, står i spidsen for et europæisk forskningsprojekt, der bl.a. med seks værktøjer skal reducere unødvendigt forbrug af antibiotika med 40 pct. i 4 udvalgte lande
Researchers at The University of Queensland have used satellites with radar imaging sensors to see through clouds and map flooding and say the technique could provide faster, more detailed information to keep communities safe.
Using radial velocity measurements, astronomers from Japan and China have detected a new exoplanet orbiting a G-type giant star. The newfound alien world is similar in mass to Jupiter but much hotter than the solar system's biggest planet. The discovery is reported in a paper published November 12 on the arXiv pre-print server.
The Perseverance rover has experienced more than 600 Martian days since its landing in February 2021. During its 8-mile (13-kilometer) drive, the robot has collected more than a dozen samples that are destined for Earth in the next few years. NASA now reports that Perseverance has spotted an alluring bit of bedrock to add to its collection. The rock outcrop, in an era called Yori Pass, could cont
A team of synthetic biologists has recently discovered a way that could increase synthetic mRNA's protein production efficiency by up to 10 times, which means the effectiveness of mRNA vaccines and drugs — such as those used against cancer, COVID-19 or other genetic diseases, will be greatly boosted with even less dosage of the mRNAs.
A team of synthetic biologists has recently discovered a way that could increase synthetic mRNA's protein production efficiency by up to 10 times, which means the effectiveness of mRNA vaccines and drugs — such as those used against cancer, COVID-19 or other genetic diseases, will be greatly boosted with even less dosage of the mRNAs.
Researchers have demonstrated a new technique for directly printing electronic circuits onto curved and corrugated surfaces. The work paves the way for a variety of new soft electronic technologies, and researchers have used the technique to create prototype "smart" contact lenses, pressure-sensitive latex gloves, and transparent electrodes. (Credit: Yuxuan Liu) "There are many existing technique
Women living in high-cost rental areas are more likely to suffer hemorrhage, heart failure, and other life-threatening outcomes during labor and delivery, new research in New Jersey shows. Researchers found an even greater discrepancy for those women without a high school education with 260 life-threatening maternal health outcomes for every 10,000 deliveries in New Jersey, including heart failur
Nature Communications, Published online: 23 November 2022; doi:10.1038/s41467-022-34668-w Population-based studies can provide information on the safety of COVID-19 vaccines. Here the authors report the rates thrombosis and thrombocytopenia after vaccination against and infection with SARS-CoV-2 in the United Kingdom and compare them with the background (expected) rates in the general population.
Nature Communications, Published online: 23 November 2022; doi:10.1038/s41467-022-35009-7 Magnetite is rarely present on the Moon. Here the authors report the magnetite formed by eutectic reaction during the impact process in Chang'E-5 lunar soil, and the potential contribution of this magnetite formation to magnetic anomalies on the Moon.
Nature Communications, Published online: 23 November 2022; doi:10.1038/s41467-022-34950-x A California stalagmite records vegetation shifts and increased fire activity during the 8.2 kyr event. These changes occur alongside oscillations between wet and dry extremes suggesting tight coupling between climate whiplash and fire activity.
Since the start of 2022, I've consumed more than my body weight in sweet potatoes. The average American eats closer to the equivalent of one (1) fry a day, but for the past decade, I've had at least half a pound of the roots at almost every dinner. I travel with sweet potatoes more reliably than I travel with my spouse. All I need in order to chow down is a microwave and something to cushion my h
"No food is sadder than personal pizza" is something I once read and promptly disagreed with. There are hundreds of objectively sadder foods. An unsold pie in a deli case, for example, is a celebratory food that should be shared at a bustling table but is now wasting away in isolation. There is the sadness of an unattended lemonade stand or of free samples when no one takes any. An untouched tray
In the more than two years since gun violence suddenly began to rise in cities all across the country, researchers have been asked repeatedly to explain what caused the rapid increase and what can be done to reverse it. The urgency behind the question is warranted: Gun homicides rose by 34 percent from 2019 to 2020, and then rose again in 2021. In Chicago alone, over 250 more people were murdered
Individuals previously infected with SARS-CoV-2, the virus that causes COVID-19, still benefit from vaccination, gaining 60% to 94% protection against reinfection, depending on the variant, according to a new study.
Vaginal birth after a previous cesarean section is associated with an increased risk of pelvic floor surgery compared with planning another cesarean, according to a new study. The findings provide useful information to help women who have had a previous cesarean section when planning how to give birth in their next pregnancy.
Conception within three months of a miscarriage or an abortion is not associated with increased risks of adverse pregnancy outcomes, according to new research. The study suggests that, contrary to current advice, women could attempt pregnancy after a previous miscarriage or induced abortion without elevated perinatal risks and reassures those who want to try again sooner than guidelines recommend.
The living worm Caenorhabditis elegans (C. elegans) has ~60% gene similarity to humans. This similarity has been studied to develop therapies for age-induced diseases, such as Alzheimer's disease and amyotrophic lateral sclerosis. However, the research investigating these worms needs advancement to reveal relationships between locomotion abilities and sensory neurons.
The living worm Caenorhabditis elegans (C. elegans) has ~60% gene similarity to humans. This similarity has been studied to develop therapies for age-induced diseases, such as Alzheimer's disease and amyotrophic lateral sclerosis. However, the research investigating these worms needs advancement to reveal relationships between locomotion abilities and sensory neurons.
Researchers have discovered that it is not just molecular density, but also pattern and structural rigidity, that control super-selective binding interactions between nanomaterials and protein surfaces. The breakthrough could help optimize existing approaches to virus prevention and cancer detection.
Scientists have successfully enhanced cultivation of a microorganism that can fix nitrogen (N2) while producing methane (CH4) and ammonia (NH3) and investigated exciting details of its metabolism.
From human intestines to the bottom of the sea: Microorganisms populate nearly any habitat, no matter how hostile it is. Their great variety of survival strategies is of huge potential in biotechnology. Most of these organisms, however, are unknown, because they cannot be cultivated. To make better use of this 'microbial dark matter', a team of researchers has now developed a 'sponge' made of poro
People who eat or drink more foods with antioxidant flavonols, which are found in several fruits and vegetables as well as tea and wine, may have a slower rate of memory decline, according to a new study.
A decline in the element molybdenum across the planet's oceans preceded a significant extinction event approximately 183 million years ago, new research shows.
In the past, PCBs were utilized in a vast range of industrial and commercial products. These highly carcinogenic chemical compounds remain in our environment and accumulate inside organisms. Chiral PCBs are particularly dangerous because they have more chlorine atoms, which are hard for the body to break down, so they can accumulate in the body easily. Also, their isomers are metabolized different
Aquifer thermal energy storage systems can largely contribute to climate-friendly heating and cooling of buildings: Heated water is stored in the underground and pumped up, if needed. Researchers have now found that low-temperature aquifer thermal energy storage is of great potential in Germany. This potential is expected to grow in future due to climate change.
Researchers have discovered that it is not just molecular density, but also pattern and structural rigidity, that control super-selective binding interactions between nanomaterials and protein surfaces. The breakthrough could help optimize existing approaches to virus prevention and cancer detection.
Scientists have successfully enhanced cultivation of a microorganism that can fix nitrogen (N2) while producing methane (CH4) and ammonia (NH3) and investigated exciting details of its metabolism.
A completely new type of microscope can take 3D images of cells — while working in a natural environment. The new technology is significantly faster and better than before and will give researchers new opportunities.
A new study shows that eye movements during the processing of tasks provide information about what the respective person is currently occupied with and what goals are being pursued within the task. These findings could play a role in the organization of screen work in the future.
Even people who tend to think conventionally, such as accountants or insurance adjusters, can be creative, a recent study suggests, if they can look at emotional situations in a different light. In a set of experiments, researchers found that conventional thinkers, those who rank low on openness to new ideas and experiences, came up with more creative ideas than peers after they practiced 'emotion
In severe epilepsies, surgical intervention is often the only remedy — usually with great success. While neuropsychological performance can recover in the long term after successful surgery, on rare occasions, unexpected declines in cognitive performance occur. Researchers have now been able to show which patients are at particularly high risk for this.
From human intestines to the bottom of the sea: Microorganisms populate nearly any habitat, no matter how hostile it is. Their great variety of survival strategies is of huge potential in biotechnology. Most of these organisms, however, are unknown, because they cannot be cultivated. To make better use of this 'microbial dark matter', a team of researchers has now developed a 'sponge' made of poro
New research has identified a new hallmark of the neurodegenerative disorder, amyotrophic lateral sclerosis (ALS), revealing a likely molecular trigger of the disease.
Another meta-analysis shows that acupuncture is nothing but an elaborate placebo, and again is misrepresented in the press. The post first appeared on Science-Based Medicine .
Nature Communications, Published online: 23 November 2022; doi:10.1038/s41467-022-34800-w The human genome harbors more than 4.5 million transposable element (TE)-derived insertions, the result of recurrent waves of invasion and internal propagation. Here they show that TEs belonging to evolutionarily recent subfamilies go on to regulate later stages of human embryonic development, notably condit
Nature Communications, Published online: 23 November 2022; doi:10.1038/s41467-022-34598-7 Chemical libraries with skeleton diversity are important for drug discovery. Here, the authors establish a synthetic methodology-based compound library (SMBL), and apply it to identify a small-molecule inhibitor to interrupt a challenging target: the protein–protein interaction (PPI) of GIT1/β-Pix.
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34670-2 X-ray photoelectron spectroscopy probes the chemical environment in a molecule at a specific atomic site. Here the authors extend this concept with a site selective trigger to follow chemical bond changes as they occur on the femtosecond time scale.
Meta has created an AI that can beat humans at an online version of Diplomacy, a popular strategy game in which seven players compete for control of Europe by moving pieces around on a map. Unlike other board games that AI has mastered, such as chess and Go , Diplomacy requires players to talk to each other—forming alliances, negotiating tactics—and spot when others are bluffing. The AI, called C
The company's past failings place its security under scrutiny by the Federal Trade Commission until 2042. Any new mishaps could lead to heavy penalties.
The World Health Organization has changed its stance on "kangaroo care" for premature or small newborns who are clinically unstable, now recommending they have this skin-to-skin contact before incubation
Nature, Published online: 23 November 2022; doi:10.1038/d41586-022-03773-7 The film's flexibilty, rare in 'thermoelectric' materials, could make it useful for powering wearable devices.
For the first time in human history, we have rudimentary planetary defense technology that could someday prevent a major asteroid impact. However, a new study from NASA's Goddard Institute for Space Studies calls attention to a more likely and harder-to-solve apocalypse: volcanoes. The study points to Venus as an example, suggesting that a period of volcanic activity lasting millions of years may
Large sporting events often claim to be carbon neutral. But often this assertion is greenwashing, and it hides the incredible amount of pollution they actually create
12-timers arbejdsdage og stressende vagtskemaer. Det er den typiske hverdag for kommunelægerne – de praktiserende læger på Færøerne. Øg normeringerne, og uddan flere unge læger i almen medicin, foreslår Marjus Dam, formand for PLO på Færøerne.
Kort transporttid, afslappet kultur og en fantastisk hjælpsomhed var, hvad familien Berthou mødte, da de flyttede til Klaksvik på Færøerne. »Vi flytter ikke tilbage til Danmark,« siger Thomas Berthou, speciallæge i almen medicin.
The chromosome may contain regions that promote their DNA's spread by killing sperm that carry Y chromosomes. However, Y chromosomes may have evolved counter mechanisms over time
This is Work in Progress, a newsletter by Derek Thompson about work, technology, and how to solve some of America's biggest problems. Sign up here to get it every week . Sam Bankman-Fried, the disgraced founder of the trading platform FTX, was a member of two cults. Or, more precisely, he was a figurehead of two movements that outsiders considered cultish. One of these movements I have criticized
A nyone who's been in a dumb recurring fight knows that the entire problem could be cleared up if everyone could just agree on exactly what was said or done . But you can't, so you end up stuck in a cycle of relitigation. Housing-policy discussions are like that. They descend into crushing bickering because even the basic facts are up for debate. The most basic fact about the housing crisis is th
Från och med i höst ska skolans sexualundervisning vara mer anpassad till den verklighet som eleverna faktiskt möter. Samtidigt har frågorna egentligen inte förändrats så mycket sedan femtiotalet visar en studie från Stockholms universitet. Inlägget dök först upp på forskning.se .
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34878-2 There is still an unmet need for effective and safe drugs to treat deep vein thrombosis during pregnancy, a life-threatening condition for the mother and fetus. Here, the authors show that engineered multifunctional nanoparticles can site-specifically dissolve thrombi and reverse deep vein thrombosis-mediate
The chromosome may contain regions that promote their DNA's spread by killing sperm that carry Y chromosomes. However, Y chromosomes may have evolved counter mechanisms over time
Images and footage of the black-naped pheasant-pigeon were recently captured by scientists. This is the first documented sighting of the elusive bird since 1882.
Male great bustards seek out two toxic plants during the birds' breeding season, and extracts from these plants have been found to kill common pathogens in the lab
Der har været stor usikkerhed blandt patienter og læger om, hvad der sker med JAK-hæmmeren Oluminant, som trods forsommerens godkendelse mod pletskaldethed ikke havde udsigt til at nå danske patienter. Efter stort pres har firmaet bag lægemidlet og de danske myndigheder taget sagen op. Om behandlingen ender på sygehus eller i primærsektor, er dog endnu uklart.
China Report is MIT Technology Review's newsletter about technology developments in China. Sign up to receive it in your inbox every Tuesday. This morning, I published an explainer on China's social credit system. The government released a draft law on November 14 that will eventually serve as the top-level guidance on how the country builds the system. That's right, the national Chinese social c
Nature Communications, Published online: 23 November 2022; doi:10.1038/s41467-022-34669-9 Population-based studies can provide information on the safety of COVID-19 vaccines. Here the authors report the rates of thrombosis and thrombocytopenia after vaccination against and infection with SARS-CoV-2 in Catalonia, Spain and compare them with the background (expected) rates in the general population
From the ashes of the giants of Big Basin Redwoods State Park arise a history of fire suppression and real questions about what happens to the forests in a drought-stricken West Coast going forward.
Nature, Published online: 23 November 2022; doi:10.1038/d41586-022-03794-2 This year, surgeons transplanted the first pig organs into human recipients. Researchers are keen to launch more human trials.
From the ashes of the giants of Big Basin Redwoods State Park arise a history of fire suppression and real questions about what happens to the forests in a drought-stricken West Coast going forward.
In a new study published in the journal Plants, People, Planet, scientists from the Royal Botanic Gardens, Kew, the Natural Resources Institute (NRI) of the University of Greenwich, UK, the Alliance of Bioversity International & CIAT (the International Center for Tropical Agriculture), and Hawassa University, Ethiopia, have found that smallholder farmers in Ethiopia grow more of the indigenous cro
In a new study published in the journal Plants, People, Planet, scientists from the Royal Botanic Gardens, Kew, the Natural Resources Institute (NRI) of the University of Greenwich, UK, the Alliance of Bioversity International & CIAT (the International Center for Tropical Agriculture), and Hawassa University, Ethiopia, have found that smallholder farmers in Ethiopia grow more of the indigenous cro
For the sake of the planet, Les Knight, the founder of the Voluntary Human Extinction movement, has spent decades pushing one message: "May we live long and die out."
Nature, Published online: 21 November 2022; doi:10.1038/d41586-022-03812-3 The final text from the global climate conference fell flat on fossil fuels but delivered a long-sought agreement on 'loss and damage'. Plus, say goodbye to the 'leap second' and learn how to protect your ideas from getting scooped.
Rising temperatures are fuelling widespread environmental degradation across Australia and supercharging natural disasters, according to a government report released Wednesday in the wake of flash floods on the country's east coast.
Det finns alternativ till kalhyggen när man avverkar skog, men många vågar sig inte på dem. Här är skälen till att skogsaktörer tvekar, enligt forskning från Lunds universitet. Inlägget dök först upp på forskning.se .
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34725-4 Shrinking of the Laurentide Ice Sheet mobilized the underlying rock organic carbon. Together with permafrost carbon release, this may contribute 12 ppm to deglacial CO2 rise, underscoring the impact of cryospheric change on the carbon cycle.
The European Space Agency will vote on Wednesday on whether to spend billions more euros to keep up with rising competition in space, as well as unveiling its much-anticipated new crop of astronauts.
A magnitude-5.9 earthquake hit a town in northwestern Turkey early Wednesday, causing damage to some buildings and widespread panic. Around 50 people were injured, mostly while trying to flee homes.
Nucleic acid therapies involving DNA or RNA have significant potential to treat genetic disorders, infectious diseases, and cancer; however, research suggests that less than 1% of injected nucleic acid doses reach target cells in an active form. An article in WIREs Nanomedicine and Nanobiotechnology highlights two of the major barriers to this therapeutic strategy, and how they might be overcome.
Koldioxidinfångning förväntas spela en viktig roll framöver, men det är en ofta dyr och krävande process. Forskare vid Luleå tekniska universitet testar nu en ny teknik, från ett fabrikstak i Piteå. Inlägget dök först upp på forskning.se .
Uppvärmningen i Europa under sommarhalvåret går betydligt snabbare än temperaturökningen för jorden som helhet. Utsläpp av växthusgaser innebär att klimatet också blivit torrare, framför allt i södra Europa. Utvecklingen innebär en ökad risk för fler värmeböljor och bränder. Inlägget dök först upp på forskning.se .
Experts from the University of Manchester have claimed that the government is misleading the public by claiming that modern slavery can be eradicated by toughening up border controls and extending sentence lengths for offenders.
Researchers have investigated the capability of known quantum computing algorithms for fault-tolerant quantum computing to simulate the laser-driven electron dynamics of excitation and ionization processes in small molecules. Their research is published in the Journal of Chemical Theory and Computation.
The world's major writing systems have tended to simplify over time, with a notable exception: New research shows that the Chinese writing system has become increasingly complex over the course of its 3000-year history.
Many of the world's most inspiring solutions have been created by scientists who stole their ideas from the natural world Read more: What happens when humans meddle with nature? Over millions of years of evolution, nature has worked out solutions to many problems. Humans have arrived late in the day and pinched them. For example, Velcro was invented after a Swiss engineer marvelled at the burdock
Changes in atmospheric pressure can set soils in motion hours or even days after heavy rain Can a change in the weather trigger a landslide? Sometimes, yes, according to research. Most landslides are set in motion by an earthquake or torrential rain, but some have no obvious trigger. In 2009, scientists were stunned to discover that the stop-start Slumgullion landslide in the Rocky Mountains – wh
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34541-w Storage of information, in any form, relies on patterns standing out from thermal fluctuations. In this work, the authors highlight a fundamental tradeoff quantifying the minimum amount of nonequilibrium resources needed to achieve a target level of accuracy in the processing of information.
Deep in South Africa's gold and platinum mines, sudden rockfalls are the leading cause of fatal accidents. But new tools using radar technology can monitor tiny shifts in the rock surrounding an underground mine, possibly forecasting incidents before then happen. Will the new tech eliminate deaths?
Bakteriofager är virus som angriper bakterier. Bakterierna har dock utvecklat försvarsstrategier för att skydda sig mot virusangreppen. För att kunna använda bakteriofager i terapier mot antibiotikaresistenta bakteriella infektioner, är det centralt att förstå hur bakteriens försvar mot bakteriofager fungerar. Nu har ett internationellt forskarteam upptäckt en tidigare okänd försvarsmekanism och k
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34974-3 Dust storms on Mars drive water escape to space. Here, the authors show the impact Martian dust storms have on the abundance of atmospheric hydrogen and oxygen, and how this helps to overall oxidize the Martian atmosphere.
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34993-0 The receptor-interacting protein (RIPK1) promotes cell death and contributes to nonalcoholic steatohepatitis pathogenesis. Here the authors report that a SUMO-specific protease, SENP1, deSUMOylates RIPK1 and inhibits cell death in a mouse model of non-alcoholic fatty liver disease.
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34949-4 The authors report photolytic H atom transfer reactions of HOSO• in astronomical CO & CO2 ices, forming reactive acyl radicals & molecular complexes with SO & SO2. Connecting the photochemistry of S oxides & C oxides in cold molecular clouds in the interstellar medium.
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34937-8 In this work the authors provide a computational workflow for the parallel, from scratch, design of proteins to rapidly explore the shape diversity of protein folds.
Self-camouflage is just one of the tricks of Brenner's bobtail squid, a newly found species that is also helping research into microbes in the human gut Bobtail squid are the second smallest group of squid in the world, at between 1cm and 5cm from neck to rounded, stumpy butt, and they only come out at night. In 2019 , scientists named a new species, Brenner's bobtail squid ( Euprymna brenneri ),
PLUS. En gruppe af industrifolk, investorer og politikere har investeret næsten 60 milliarder kroner i at gøre Nordsverige til et kraftcenter for udvikling og produktion af batterier.
If you see a great bustard (Otis tarda) in the wild, you're unlikely to forget it. Massive, colorful, and impossible to mistake, they are the heaviest birds living today capable of flight, with the greatest size difference between the sexes. They are also "lek breeders," where males gather at chosen sites to put on an audiovisual show for the visiting females, who choose a mate based on his appear
Pancake/flatbread with a 'nutty' taste is first evidence of complex cooking and food culture If you thought Neanderthals survived on a diet of foraged berries and uncooked animal flesh, think again. Charred remnants of what appear be the world's oldest cooked meal ever found have been unearthed in a cave complex in northern Iraq, prompting speculation that Neanderthals may have been foodies. "Our
If you see a great bustard (Otis tarda) in the wild, you're unlikely to forget it. Massive, colorful, and impossible to mistake, they are the heaviest birds living today capable of flight, with the greatest size difference between the sexes. They are also "lek breeders," where males gather at chosen sites to put on an audiovisual show for the visiting females, who choose a mate based on his appear
Using radial velocity measurements, astronomers from Japan and China have detected a new exoplanet orbiting a G-type giant star. The newfound alien world is similar in mass to Jupiter but much hotter than the solar system's biggest planet. The discovery is reported in a paper published November 12 on the arXiv pre-print server.
My brother arrived in my life like the rain always did: after fervent prayer and petitioning. My father was a crop duster in the Texas Panhandle, a land where memories of the Dust Bowl remained painfully fresh even as the farmers remained stubbornly persistent. And so we were always praying for rain, before Friday-night high-school football games, around the dinner table, at church on Sunday morn
This is today's edition of The Download , our weekday newsletter that provides a daily dose of what's going on in the world of technology. Meta's game-playing AI can make and break alliances like a human Meta has created an AI that can beat humans at an online version of Diplomacy, a popular strategy game in which seven players compete for control of Europe by moving pieces around on a map. Unlik
Supermassive black holes that beam powerful jets of matter towards Earth, known as blazars, accelerate particles to extraordinarily high energies – and astronomers have finally figured out how
Physicists at the University of Basel have experimentally demonstrated for the first time that there is a negative correlation between the two spins of an entangled pair of electrons from a superconductor. For their study, the researchers used spin filters made of nanomagnets and quantum dots, as they report in the scientific journal Nature.
A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.
A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.
Hackathon In the hours after the FTX cryptocurrency exchange filed for bankruptcy, opportunistic hackers — or possibly an insider — took advantage of the chaos and began looting hundreds of millions of dollars worth of crypto. Now, it appears, they're hard at work laundering it. As CNBC reports , the exchange's new CEO, John Ray III, admitted when the company filed for bankruptcy earlier in the m
Nature, Published online: 23 November 2022; doi:10.1038/d41586-022-04122-4 The ExoMars programme was imperilled after the European Space Agency cut ties with its former partner Russia.
Scientists looking to understand the fundamental brain mechanisms of autism spectrum disorder have found that a gene mutation known to be associated with the disorder causes an overstimulation of brain cells far greater than that seen in neuronal cells without the mutation. The study, spanning seven years, employed some of the most advanced approaches available in the scientific toolbox, including
Bringing transparency to how a vaccine becomes a vaccine, Dr. Jen Gunter breaks down research, development and testing that makes these life-saving therapeutics safe — long before they reach your local pharmacy. For more on how your body works, tune in weekly to her podcast Body Stuff with Dr. Jen Gunter, from the TED Audio Collective.
In the Northern Hemisphere, this year's winter hasn't yet begun. But Melissa J. Sacco, a pediatric-intensive-care specialist at UVA Health, is already dreading the arrival of the one that could follow. For months, the ICU where Sacco works has been overflowing with children amid an early-arriving surge of respiratory infections. Across the country, viruses such as RSV and flu, once brought to nea
There was a moment a few years ago when I couldn't help but cringe a little every time I heard the word story , so wantonly was it being bandied about. This was during the Trump administration, when lots of people still sweetly believed that culture could counter raw political power, that protest art could engender a sense of shame among the shameless, even that satire might have the capacity to
With Black Friday and Cyber Monday upon us, Rutgers University experts weigh in on the holiday retail season, including how you can save money while focusing on holiday cheer: The post appeared first on Futurity .
New research charts the radical evolutionary changes to the thigh bones of dinosaurs and birds that allowed them to stand on two feet. The findings resolve a longstanding question about dinosaur evolution and offer a prime example of how new physical features can pop up briefly during embryonic development and then give way to older, known features in adults. The new study shows how changes in th
Mathematicians love a good puzzle. Even something as abstract as multiplying matrices (two-dimensional tables of numbers) can feel like a game when you try to find the most efficient way to do it. It's a little like trying to solve a Rubik's Cube in as few moves as possible — challenging, but alluring. Except that for a Rubik's Cube, the number of possible moves at each step is 18… Source
What could be one of Norway's oldest shipwrecks has been found on the bottom of a lake near Oslo, during an effort to locate the tons of unexploded ammunition dumped there since World War II.
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
A recent study has discovered and characterized secreted proteins from the pathogen Candidatus Liberibacter solanacearum. These proteins, called effectors, offer clues into the manipulation tactics this bacterium uses to subdue its plant host. The study found that these effectors can be present in both the plant and insect host.
An ambitious plan to sequence the genomes of all known species of euglenoids over the next decade has been launched. The network of scientists behind the initiative believe it has the potential to drive breakthroughs ranging from new biofuels and sustainable foods to cancer medicines.
Researchers have found that administering remdesivir with corticosteroids to Asian patients who are critically ill with COVID-19 within 9 days of symptom onset reduces overall mortality. Starting treatment later did not have the same effect, suggesting that higher viral loads and serious lung damage impair the effectiveness of this treatment.
Scientists have produced a proof of concept for a new and better way of caring for women facing the life-threatening situation of ectopic pregnancy, which occurs when a fertilized egg implants somewhere other than the lining of the uterus.
The holiday season is filled with hearty, delicious food, visiting with friends and family, decreased physical activity, busy schedules and weight gain. According to a Kansas State University veterinarian, it is also a time for our family pets to gain weight as well.
I have been writing a lot recently about global warming and energy infrastructure. This is partly because there is a lot of news coming out of COP27, but also because both here and on the SGU there has been some lively and informative discussion on the issue. Also, this is a very complex issue and as people raise new points it sends me down different rabbit holes of information. I am trying to de
The holiday season is filled with hearty, delicious food, visiting with friends and family, decreased physical activity, busy schedules and weight gain. According to a Kansas State University veterinarian, it is also a time for our family pets to gain weight as well.
Thanksgiving may be right around the corner, but Maine's wild turkeys have more to worry about than ending up on the kitchen table. Winter is coming, and with it, extremely cold temperatures and fewer resources for turkeys to thrive. According to a University of Maine study, wild turkeys will adjust their movements in inclement winter weather to increase their odds of survival, but their behaviors
Submerged below the waves of the English Channel lies an important scientific record of undiscovered Neanderthal artifacts dating back to the last ice age. Collecting them from beneath the channel's cold waters is no easy feat, but UCL researchers found a way to get a brief peek at the otherwise hidden landscape.
The early 2020s have been a chaotic time, with seemingly one crisis after another befalling humanity: the Covid-19 pandemic, inflation and supply chain upheaval, political instability and extremism, climate change…the list goes on. But what does it all really mean, or matter, when you zoom out and look at the big picture? An astronomy professor from Johns Hopkins University has given us the chanc
An ambitious plan to sequence the genomes of all known species of euglenoids over the next decade has been launched. The network of scientists behind the initiative believe it has the potential to drive breakthroughs ranging from new biofuels and sustainable foods to cancer medicines.
New research demonstrates that certain chemical coatings, applied to micro/nanoparticles, can alter their swimming propulsion within biological fluids.
Thanksgiving may be right around the corner, but Maine's wild turkeys have more to worry about than ending up on the kitchen table. Winter is coming, and with it, extremely cold temperatures and fewer resources for turkeys to thrive. According to a University of Maine study, wild turkeys will adjust their movements in inclement winter weather to increase their odds of survival, but their behaviors
Nature, Published online: 23 November 2022; doi:10.1038/d41586-022-03767-5 Structural insights into a long-studied folate-transport protein provide evidence that might lead to entirely new targeted anticancer treatments, or boost the success of immunotherapy approaches to tackling tumours.
Nature, Published online: 21 November 2022; doi:10.1038/d41586-022-03774-6 People in the United States tend to associate with others who hold views that are similar to their own — but more radical.
Virtual 3D tours on real estate websites, such as Zillow and Redfin, could pose privacy risks to the current residents. Sometimes the homes in these tours are staged, but other times they contain evidence of current residents' lives. University of Washington researchers were curious about whether personal belongings visible in 3D tours could introduce privacy risks. The team examined 44 3D tours
There is a less obvious source of carbon emissions than cars and factories: rivers and streams. Inland waters release carbon in the atmosphere, but their contributions depend on their concentration of dissolved inorganic carbon (DIC) from minerals and other sources. But what factors impact DIC concentrations? A team of Penn State engineers has now determined that both water discharge—or the volume
Three currently circulating omicron subvariants of SARS-CoV-2 are better at evading vaccine- and infection-generated neutralizing antibodies than earlier versions of omicron, new research suggests.
New research demonstrates that certain chemical coatings, applied to micro/nanoparticles, can alter their swimming propulsion within biological fluids.
På bagkant af amputationssagen bør vi diskutere variation i sundhedsvæsenet. For er variation i sundhedsvæsenets behandling og resultater altid et problem, eller er variation faktisk grundlaget for læring og udvikling? Efter amputationssagen er der behov for at få en nuanceret debat om variation i sundhedsvæsenet og at variation også er en mulighed for læring og udvikling.
Professor på Center for Almen Medicin på Københavns Universitet, Lars Bjerrum, står i spidsen for et europæisk forskningsprojekt, der bl.a. med seks værktøjer skal reducere unødvendigt forbrug af antibiotika med 40 pct. i 4 udvalgte lande
Researchers at The University of Queensland have used satellites with radar imaging sensors to see through clouds and map flooding and say the technique could provide faster, more detailed information to keep communities safe.
The Perseverance rover has experienced more than 600 Martian days since its landing in February 2021. During its 8-mile (13-kilometer) drive, the robot has collected more than a dozen samples that are destined for Earth in the next few years. NASA now reports that Perseverance has spotted an alluring bit of bedrock to add to its collection. The rock outcrop, in an era called Yori Pass, could cont
A team of synthetic biologists has recently discovered a way that could increase synthetic mRNA's protein production efficiency by up to 10 times, which means the effectiveness of mRNA vaccines and drugs — such as those used against cancer, COVID-19 or other genetic diseases, will be greatly boosted with even less dosage of the mRNAs.
A team of synthetic biologists has recently discovered a way that could increase synthetic mRNA's protein production efficiency by up to 10 times, which means the effectiveness of mRNA vaccines and drugs — such as those used against cancer, COVID-19 or other genetic diseases, will be greatly boosted with even less dosage of the mRNAs.
Researchers have demonstrated a new technique for directly printing electronic circuits onto curved and corrugated surfaces. The work paves the way for a variety of new soft electronic technologies, and researchers have used the technique to create prototype "smart" contact lenses, pressure-sensitive latex gloves, and transparent electrodes. (Credit: Yuxuan Liu) "There are many existing technique
Women living in high-cost rental areas are more likely to suffer hemorrhage, heart failure, and other life-threatening outcomes during labor and delivery, new research in New Jersey shows. Researchers found an even greater discrepancy for those women without a high school education with 260 life-threatening maternal health outcomes for every 10,000 deliveries in New Jersey, including heart failur
Nature Communications, Published online: 23 November 2022; doi:10.1038/s41467-022-34668-w Population-based studies can provide information on the safety of COVID-19 vaccines. Here the authors report the rates thrombosis and thrombocytopenia after vaccination against and infection with SARS-CoV-2 in the United Kingdom and compare them with the background (expected) rates in the general population.
Nature Communications, Published online: 23 November 2022; doi:10.1038/s41467-022-35009-7 Magnetite is rarely present on the Moon. Here the authors report the magnetite formed by eutectic reaction during the impact process in Chang'E-5 lunar soil, and the potential contribution of this magnetite formation to magnetic anomalies on the Moon.
Nature Communications, Published online: 23 November 2022; doi:10.1038/s41467-022-34950-x A California stalagmite records vegetation shifts and increased fire activity during the 8.2 kyr event. These changes occur alongside oscillations between wet and dry extremes suggesting tight coupling between climate whiplash and fire activity.
Since the start of 2022, I've consumed more than my body weight in sweet potatoes. The average American eats closer to the equivalent of one (1) fry a day, but for the past decade, I've had at least half a pound of the roots at almost every dinner. I travel with sweet potatoes more reliably than I travel with my spouse. All I need in order to chow down is a microwave and something to cushion my h
"No food is sadder than personal pizza" is something I once read and promptly disagreed with. There are hundreds of objectively sadder foods. An unsold pie in a deli case, for example, is a celebratory food that should be shared at a bustling table but is now wasting away in isolation. There is the sadness of an unattended lemonade stand or of free samples when no one takes any. An untouched tray
In the more than two years since gun violence suddenly began to rise in cities all across the country, researchers have been asked repeatedly to explain what caused the rapid increase and what can be done to reverse it. The urgency behind the question is warranted: Gun homicides rose by 34 percent from 2019 to 2020, and then rose again in 2021. In Chicago alone, over 250 more people were murdered
Individuals previously infected with SARS-CoV-2, the virus that causes COVID-19, still benefit from vaccination, gaining 60% to 94% protection against reinfection, depending on the variant, according to a new study.
Vaginal birth after a previous cesarean section is associated with an increased risk of pelvic floor surgery compared with planning another cesarean, according to a new study. The findings provide useful information to help women who have had a previous cesarean section when planning how to give birth in their next pregnancy.
Conception within three months of a miscarriage or an abortion is not associated with increased risks of adverse pregnancy outcomes, according to new research. The study suggests that, contrary to current advice, women could attempt pregnancy after a previous miscarriage or induced abortion without elevated perinatal risks and reassures those who want to try again sooner than guidelines recommend.
The living worm Caenorhabditis elegans (C. elegans) has ~60% gene similarity to humans. This similarity has been studied to develop therapies for age-induced diseases, such as Alzheimer's disease and amyotrophic lateral sclerosis. However, the research investigating these worms needs advancement to reveal relationships between locomotion abilities and sensory neurons.
The living worm Caenorhabditis elegans (C. elegans) has ~60% gene similarity to humans. This similarity has been studied to develop therapies for age-induced diseases, such as Alzheimer's disease and amyotrophic lateral sclerosis. However, the research investigating these worms needs advancement to reveal relationships between locomotion abilities and sensory neurons.
Researchers have discovered that it is not just molecular density, but also pattern and structural rigidity, that control super-selective binding interactions between nanomaterials and protein surfaces. The breakthrough could help optimize existing approaches to virus prevention and cancer detection.
Scientists have successfully enhanced cultivation of a microorganism that can fix nitrogen (N2) while producing methane (CH4) and ammonia (NH3) and investigated exciting details of its metabolism.
From human intestines to the bottom of the sea: Microorganisms populate nearly any habitat, no matter how hostile it is. Their great variety of survival strategies is of huge potential in biotechnology. Most of these organisms, however, are unknown, because they cannot be cultivated. To make better use of this 'microbial dark matter', a team of researchers has now developed a 'sponge' made of poro
People who eat or drink more foods with antioxidant flavonols, which are found in several fruits and vegetables as well as tea and wine, may have a slower rate of memory decline, according to a new study.
A decline in the element molybdenum across the planet's oceans preceded a significant extinction event approximately 183 million years ago, new research shows.
In the past, PCBs were utilized in a vast range of industrial and commercial products. These highly carcinogenic chemical compounds remain in our environment and accumulate inside organisms. Chiral PCBs are particularly dangerous because they have more chlorine atoms, which are hard for the body to break down, so they can accumulate in the body easily. Also, their isomers are metabolized different
Aquifer thermal energy storage systems can largely contribute to climate-friendly heating and cooling of buildings: Heated water is stored in the underground and pumped up, if needed. Researchers have now found that low-temperature aquifer thermal energy storage is of great potential in Germany. This potential is expected to grow in future due to climate change.
Researchers have discovered that it is not just molecular density, but also pattern and structural rigidity, that control super-selective binding interactions between nanomaterials and protein surfaces. The breakthrough could help optimize existing approaches to virus prevention and cancer detection.
Scientists have successfully enhanced cultivation of a microorganism that can fix nitrogen (N2) while producing methane (CH4) and ammonia (NH3) and investigated exciting details of its metabolism.
A completely new type of microscope can take 3D images of cells — while working in a natural environment. The new technology is significantly faster and better than before and will give researchers new opportunities.
A new study shows that eye movements during the processing of tasks provide information about what the respective person is currently occupied with and what goals are being pursued within the task. These findings could play a role in the organization of screen work in the future.
Even people who tend to think conventionally, such as accountants or insurance adjusters, can be creative, a recent study suggests, if they can look at emotional situations in a different light. In a set of experiments, researchers found that conventional thinkers, those who rank low on openness to new ideas and experiences, came up with more creative ideas than peers after they practiced 'emotion
In severe epilepsies, surgical intervention is often the only remedy — usually with great success. While neuropsychological performance can recover in the long term after successful surgery, on rare occasions, unexpected declines in cognitive performance occur. Researchers have now been able to show which patients are at particularly high risk for this.
From human intestines to the bottom of the sea: Microorganisms populate nearly any habitat, no matter how hostile it is. Their great variety of survival strategies is of huge potential in biotechnology. Most of these organisms, however, are unknown, because they cannot be cultivated. To make better use of this 'microbial dark matter', a team of researchers has now developed a 'sponge' made of poro
New research has identified a new hallmark of the neurodegenerative disorder, amyotrophic lateral sclerosis (ALS), revealing a likely molecular trigger of the disease.
Another meta-analysis shows that acupuncture is nothing but an elaborate placebo, and again is misrepresented in the press. The post first appeared on Science-Based Medicine .
Nature Communications, Published online: 23 November 2022; doi:10.1038/s41467-022-34800-w The human genome harbors more than 4.5 million transposable element (TE)-derived insertions, the result of recurrent waves of invasion and internal propagation. Here they show that TEs belonging to evolutionarily recent subfamilies go on to regulate later stages of human embryonic development, notably condit
Nature Communications, Published online: 23 November 2022; doi:10.1038/s41467-022-34598-7 Chemical libraries with skeleton diversity are important for drug discovery. Here, the authors establish a synthetic methodology-based compound library (SMBL), and apply it to identify a small-molecule inhibitor to interrupt a challenging target: the protein–protein interaction (PPI) of GIT1/β-Pix.
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34670-2 X-ray photoelectron spectroscopy probes the chemical environment in a molecule at a specific atomic site. Here the authors extend this concept with a site selective trigger to follow chemical bond changes as they occur on the femtosecond time scale.
Meta has created an AI that can beat humans at an online version of Diplomacy, a popular strategy game in which seven players compete for control of Europe by moving pieces around on a map. Unlike other board games that AI has mastered, such as chess and Go , Diplomacy requires players to talk to each other—forming alliances, negotiating tactics—and spot when others are bluffing. The AI, called C
The company's past failings place its security under scrutiny by the Federal Trade Commission until 2042. Any new mishaps could lead to heavy penalties.
The World Health Organization has changed its stance on "kangaroo care" for premature or small newborns who are clinically unstable, now recommending they have this skin-to-skin contact before incubation
Nature, Published online: 23 November 2022; doi:10.1038/d41586-022-03773-7 The film's flexibilty, rare in 'thermoelectric' materials, could make it useful for powering wearable devices.
For the first time in human history, we have rudimentary planetary defense technology that could someday prevent a major asteroid impact. However, a new study from NASA's Goddard Institute for Space Studies calls attention to a more likely and harder-to-solve apocalypse: volcanoes. The study points to Venus as an example, suggesting that a period of volcanic activity lasting millions of years may
Large sporting events often claim to be carbon neutral. But often this assertion is greenwashing, and it hides the incredible amount of pollution they actually create
12-timers arbejdsdage og stressende vagtskemaer. Det er den typiske hverdag for kommunelægerne – de praktiserende læger på Færøerne. Øg normeringerne, og uddan flere unge læger i almen medicin, foreslår Marjus Dam, formand for PLO på Færøerne.
Kort transporttid, afslappet kultur og en fantastisk hjælpsomhed var, hvad familien Berthou mødte, da de flyttede til Klaksvik på Færøerne. »Vi flytter ikke tilbage til Danmark,« siger Thomas Berthou, speciallæge i almen medicin.
The chromosome may contain regions that promote their DNA's spread by killing sperm that carry Y chromosomes. However, Y chromosomes may have evolved counter mechanisms over time
This is Work in Progress, a newsletter by Derek Thompson about work, technology, and how to solve some of America's biggest problems. Sign up here to get it every week . Sam Bankman-Fried, the disgraced founder of the trading platform FTX, was a member of two cults. Or, more precisely, he was a figurehead of two movements that outsiders considered cultish. One of these movements I have criticized
A nyone who's been in a dumb recurring fight knows that the entire problem could be cleared up if everyone could just agree on exactly what was said or done . But you can't, so you end up stuck in a cycle of relitigation. Housing-policy discussions are like that. They descend into crushing bickering because even the basic facts are up for debate. The most basic fact about the housing crisis is th
Från och med i höst ska skolans sexualundervisning vara mer anpassad till den verklighet som eleverna faktiskt möter. Samtidigt har frågorna egentligen inte förändrats så mycket sedan femtiotalet visar en studie från Stockholms universitet. Inlägget dök först upp på forskning.se .
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34878-2 There is still an unmet need for effective and safe drugs to treat deep vein thrombosis during pregnancy, a life-threatening condition for the mother and fetus. Here, the authors show that engineered multifunctional nanoparticles can site-specifically dissolve thrombi and reverse deep vein thrombosis-mediate
The chromosome may contain regions that promote their DNA's spread by killing sperm that carry Y chromosomes. However, Y chromosomes may have evolved counter mechanisms over time
Images and footage of the black-naped pheasant-pigeon were recently captured by scientists. This is the first documented sighting of the elusive bird since 1882.
Male great bustards seek out two toxic plants during the birds' breeding season, and extracts from these plants have been found to kill common pathogens in the lab
Der har været stor usikkerhed blandt patienter og læger om, hvad der sker med JAK-hæmmeren Oluminant, som trods forsommerens godkendelse mod pletskaldethed ikke havde udsigt til at nå danske patienter. Efter stort pres har firmaet bag lægemidlet og de danske myndigheder taget sagen op. Om behandlingen ender på sygehus eller i primærsektor, er dog endnu uklart.
China Report is MIT Technology Review's newsletter about technology developments in China. Sign up to receive it in your inbox every Tuesday. This morning, I published an explainer on China's social credit system. The government released a draft law on November 14 that will eventually serve as the top-level guidance on how the country builds the system. That's right, the national Chinese social c
Nature Communications, Published online: 23 November 2022; doi:10.1038/s41467-022-34669-9 Population-based studies can provide information on the safety of COVID-19 vaccines. Here the authors report the rates of thrombosis and thrombocytopenia after vaccination against and infection with SARS-CoV-2 in Catalonia, Spain and compare them with the background (expected) rates in the general population
From the ashes of the giants of Big Basin Redwoods State Park arise a history of fire suppression and real questions about what happens to the forests in a drought-stricken West Coast going forward.
Nature, Published online: 23 November 2022; doi:10.1038/d41586-022-03794-2 This year, surgeons transplanted the first pig organs into human recipients. Researchers are keen to launch more human trials.
From the ashes of the giants of Big Basin Redwoods State Park arise a history of fire suppression and real questions about what happens to the forests in a drought-stricken West Coast going forward.
In a new study published in the journal Plants, People, Planet, scientists from the Royal Botanic Gardens, Kew, the Natural Resources Institute (NRI) of the University of Greenwich, UK, the Alliance of Bioversity International & CIAT (the International Center for Tropical Agriculture), and Hawassa University, Ethiopia, have found that smallholder farmers in Ethiopia grow more of the indigenous cro
In a new study published in the journal Plants, People, Planet, scientists from the Royal Botanic Gardens, Kew, the Natural Resources Institute (NRI) of the University of Greenwich, UK, the Alliance of Bioversity International & CIAT (the International Center for Tropical Agriculture), and Hawassa University, Ethiopia, have found that smallholder farmers in Ethiopia grow more of the indigenous cro
For the sake of the planet, Les Knight, the founder of the Voluntary Human Extinction movement, has spent decades pushing one message: "May we live long and die out."
Nature, Published online: 21 November 2022; doi:10.1038/d41586-022-03812-3 The final text from the global climate conference fell flat on fossil fuels but delivered a long-sought agreement on 'loss and damage'. Plus, say goodbye to the 'leap second' and learn how to protect your ideas from getting scooped.
Rising temperatures are fuelling widespread environmental degradation across Australia and supercharging natural disasters, according to a government report released Wednesday in the wake of flash floods on the country's east coast.
Det finns alternativ till kalhyggen när man avverkar skog, men många vågar sig inte på dem. Här är skälen till att skogsaktörer tvekar, enligt forskning från Lunds universitet. Inlägget dök först upp på forskning.se .
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34725-4 Shrinking of the Laurentide Ice Sheet mobilized the underlying rock organic carbon. Together with permafrost carbon release, this may contribute 12 ppm to deglacial CO2 rise, underscoring the impact of cryospheric change on the carbon cycle.
The European Space Agency will vote on Wednesday on whether to spend billions more euros to keep up with rising competition in space, as well as unveiling its much-anticipated new crop of astronauts.
A magnitude-5.9 earthquake hit a town in northwestern Turkey early Wednesday, causing damage to some buildings and widespread panic. Around 50 people were injured, mostly while trying to flee homes.
Nucleic acid therapies involving DNA or RNA have significant potential to treat genetic disorders, infectious diseases, and cancer; however, research suggests that less than 1% of injected nucleic acid doses reach target cells in an active form. An article in WIREs Nanomedicine and Nanobiotechnology highlights two of the major barriers to this therapeutic strategy, and how they might be overcome.
Koldioxidinfångning förväntas spela en viktig roll framöver, men det är en ofta dyr och krävande process. Forskare vid Luleå tekniska universitet testar nu en ny teknik, från ett fabrikstak i Piteå. Inlägget dök först upp på forskning.se .
Uppvärmningen i Europa under sommarhalvåret går betydligt snabbare än temperaturökningen för jorden som helhet. Utsläpp av växthusgaser innebär att klimatet också blivit torrare, framför allt i södra Europa. Utvecklingen innebär en ökad risk för fler värmeböljor och bränder. Inlägget dök först upp på forskning.se .
Experts from the University of Manchester have claimed that the government is misleading the public by claiming that modern slavery can be eradicated by toughening up border controls and extending sentence lengths for offenders.
Researchers have investigated the capability of known quantum computing algorithms for fault-tolerant quantum computing to simulate the laser-driven electron dynamics of excitation and ionization processes in small molecules. Their research is published in the Journal of Chemical Theory and Computation.
The world's major writing systems have tended to simplify over time, with a notable exception: New research shows that the Chinese writing system has become increasingly complex over the course of its 3000-year history.
Many of the world's most inspiring solutions have been created by scientists who stole their ideas from the natural world Read more: What happens when humans meddle with nature? Over millions of years of evolution, nature has worked out solutions to many problems. Humans have arrived late in the day and pinched them. For example, Velcro was invented after a Swiss engineer marvelled at the burdock
Changes in atmospheric pressure can set soils in motion hours or even days after heavy rain Can a change in the weather trigger a landslide? Sometimes, yes, according to research. Most landslides are set in motion by an earthquake or torrential rain, but some have no obvious trigger. In 2009, scientists were stunned to discover that the stop-start Slumgullion landslide in the Rocky Mountains – wh
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34541-w Storage of information, in any form, relies on patterns standing out from thermal fluctuations. In this work, the authors highlight a fundamental tradeoff quantifying the minimum amount of nonequilibrium resources needed to achieve a target level of accuracy in the processing of information.
Deep in South Africa's gold and platinum mines, sudden rockfalls are the leading cause of fatal accidents. But new tools using radar technology can monitor tiny shifts in the rock surrounding an underground mine, possibly forecasting incidents before then happen. Will the new tech eliminate deaths?
Bakteriofager är virus som angriper bakterier. Bakterierna har dock utvecklat försvarsstrategier för att skydda sig mot virusangreppen. För att kunna använda bakteriofager i terapier mot antibiotikaresistenta bakteriella infektioner, är det centralt att förstå hur bakteriens försvar mot bakteriofager fungerar. Nu har ett internationellt forskarteam upptäckt en tidigare okänd försvarsmekanism och k
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34974-3 Dust storms on Mars drive water escape to space. Here, the authors show the impact Martian dust storms have on the abundance of atmospheric hydrogen and oxygen, and how this helps to overall oxidize the Martian atmosphere.
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34993-0 The receptor-interacting protein (RIPK1) promotes cell death and contributes to nonalcoholic steatohepatitis pathogenesis. Here the authors report that a SUMO-specific protease, SENP1, deSUMOylates RIPK1 and inhibits cell death in a mouse model of non-alcoholic fatty liver disease.
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34949-4 The authors report photolytic H atom transfer reactions of HOSO• in astronomical CO & CO2 ices, forming reactive acyl radicals & molecular complexes with SO & SO2. Connecting the photochemistry of S oxides & C oxides in cold molecular clouds in the interstellar medium.
Nature Communications, Published online: 22 November 2022; doi:10.1038/s41467-022-34937-8 In this work the authors provide a computational workflow for the parallel, from scratch, design of proteins to rapidly explore the shape diversity of protein folds.
Self-camouflage is just one of the tricks of Brenner's bobtail squid, a newly found species that is also helping research into microbes in the human gut Bobtail squid are the second smallest group of squid in the world, at between 1cm and 5cm from neck to rounded, stumpy butt, and they only come out at night. In 2019 , scientists named a new species, Brenner's bobtail squid ( Euprymna brenneri ),
PLUS. En gruppe af industrifolk, investorer og politikere har investeret næsten 60 milliarder kroner i at gøre Nordsverige til et kraftcenter for udvikling og produktion af batterier.
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