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Thomas Hertog worked with cosmologist on a new book after he shared his doubts about A Brief History of Time In 2002 Thomas Hertog received an email summoning him to the office of his mentor Stephen Hawking. The young researcher rushed to Hawking's room at Cambridge. "His eyes were radiant with excitement," Hertog recalls. Typing on the computer-controlled voice system that allowed the cosmologis
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Med hjälp av ett datorprogram som annars används i brottsutredningar har man lyckats göra en rekonstruktion av faraon Ramses II:s ansikte – drygt 3 000 år efter hans död. – Vi är ganska säkra på att han såg ut så här i den åldern. Någon som kände honom när han levde skulle känna igen honom, säger rättsantropologen Caroline Wilkinson i SVT:s Vetenskapens värld – Faraos ansikte.
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Whether Donald Trump is arrested and booked on Tuesday or not for a case involving a payoff to the porn star Stormy Daniels—something only he has predicted—the potential arrest of a former United States president is not only unprecedented but actually quite technically challenging. How does one arrest a former president in a democracy that has never faced this prospect before? The fate Trump may
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I'm a computer science major trying to focus on AI and machine learning. When chat gpt became popular around I'd say January ( I don't know actual date), it was cool and eye opening especially since it could write code. Now about 2 months (March) later and this shit is godly at what it does. Combine this with all the other AI that have been becoming increasingly powerful in their capabilities. I'
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This article was originally published in Knowable Magazine . Several years ago, Christian Rutz started to wonder whether he was giving his crows enough credit. Rutz, a biologist at the University of St. Andrews, in Scotland, and his team were capturing wild New Caledonian crows and challenging them with puzzles made from natural materials before releasing them again. In one test , birds faced a l
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Daylight helps to regulate hormones and the immune system. It's good for sleep and can help with depression. So be glad of the extra daylight when the clocks go forward If we took away the walls, the ceilings, the street lights, the screens and allowed our senses to guide us, we might rise with the sun and sleep when it sets. Artificial lighting and blackout blinds allow us to choose our waking h
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Babesiosis, a severe and sometimes fatal disease carried by ticks, everyone's least-favorite discreet arachnid enemies…. Caused by parasites, babesiosis infects red blood cells and inflicts flu-like symptoms in some patients, including fever, muscle, head, and joint aches, nauseau, and fatigue.
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Control C, Control V An AI startup called Wonder Dynamics just came out with a new AI-powered editing studio called Wonder Studio, which they claim allows users to automatically replace real actors with convincing CG characters — with a simple drag and drop. Gotta say: it looks pretty impressive. "We built something that automates this whole process, animates it live, frame by frame, there's no n
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Caesar comes across some fermented monkey fruit and eats it. Before he knows it, he starts becoming incoherent. #nakedandafraid #discoveryplus Stream Full Episodes of Naked and Afraid: https://www.discoveryplus.com/show/naked-and-afraid About Naked and Afraid: One man and one woman, who meet for the first time in the nude, are paired and tasked with surviving in some of the world's most extreme e
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Am I missing something? There is a lot of handwringing over AI replacing coders. Given the current trajectory and multimodal I/O it will replace the need for discrete software applications entirely [edit: and the need for developers]. Everything can be baked into the AI 's interface: Image editor – AI please remove the peeing dog in the background of this photo of myself and my wife. AI please ch
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Venus is almost the same size, mass and density as Earth. So it should be generating heat in its interior (by the decay of radioactive elements) at much the same rate as the Earth does. On Earth, one of the main ways in which this heat leaks out is via volcanic eruptions. During an average year, at least 50 volcanoes erupt.
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Effective treatment usually requires a holistic approach, yet those suffering often avoid seeking help Many of us are familiar with the uncomfortable feeling of entering a cocktail party at which none of our friends are present. We sidle in awkwardly, imagine others might be wondering what we are doing there and find ourselves not sure where to stand or who to look at. We gaze intently at our pro
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This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. Sign up for it here . Good morning, and welcome back to The Daily's Sunday culture edition, in which one Atlantic writer reveals what's keeping them entertained. Today's special guest is the staff writer Jerusalem Demsas ,
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The U.N.'s premiere global body fighting for gender equality on Saturday called for wide-ranging efforts to close the gap between men and women in today's technology-driven world and urged zero tolerance for gender-based violence and harassment online.
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A new play explores the short life of Jeremiah Horrocks, whose astonishing discoveries 'changed the way we see the universe' On a cloudy afternoon in England in 1639, 20-year-old Jeremiah Horrocks became the first person to accurately predict the transit of Venus and measure the distance from the Earth to the sun. His work proved, for the first time, that Earth is not at the centre of the univers
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Unusual weather has created the ideal conditions for fungus, delighting foragers and researchers On a sun-dappled trail in the woods of Calabasas, Jess Starwood narrows her eyes and gasps with glee. Scrambling up a leafy hillside, she points to a small hump in the ground, covered in leaf litter. "That's a shrump," she says – a mushroom hump, where a mushroom may be pushing up the ground as it eme
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It was a nostalgic journey to rediscover my family roots, but it was also great fun and reminded me how much I missed this beautiful land When I saw the sign saying "Sweden", I cheered. I was alone in the car, but still I cheered. It was my brother's car, a white Nissan Note I had managed to dent at a petrol station within an hour of driving off Le Shuttle. Nine hundred miles on, the Nissan and I
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A chronological listing of news articles posted on the Skeptical Science Facebook Page during the past week: Sun, Mar 12, 2023 thru Sat, Mar 18, 2023. Story of the Week Guest post: What 13,500 citations reveal about the IPCC's climate science report IPCC WG1 AR6 SPM Report Cover – Changing by Alisa Singer. Credit: Alisa Singer / IPCC. In August 2021, the Intergovernmental Panel on Climate Change
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You're correct that an AI can incorporate randomization into its algorithms to generate creative outputs. However, true creativity involves more than just randomization. A genuinely creative AI should be able to understand context, evaluate its own ideas, and come up with novel solutions that are both useful and relevant to a given problem or situation. Here's how an AI model could potentially "s
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So there has been quite a lot of AI generated music lately, but nothing really "surprised" me at this point. However, as a fan of rock / metal music this one got my absolute attention: https://www.youtube.com/watch?v=rYPbdyM_-Dw However, I'm not quite sure where this will lead in the long run in terms of real bands and what it might do to some musicians (mentally). Mixed feelings. It's "scary goo
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Greetings, I am a master's student at the University of Galway conducting my dissertation. I am recruiting participants for an online experiment that aims to examine language and emotion processing when listening to multiple speakers in individuals with and without ASD. This online study would involve completing two questionnaires and two tasks on your own PC or laptop with headphones, and only t
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Elon Musk just offered a take nobody asked for, on the bad-faith "debate" regarding transgender children and access to medical care — though of course, it's not the first time the Twitter owner has waded into trans reactionary rhetoric. Responding, for some reason, to a video of Minnesota's lieutenant governor coming out in favor of trans kids' access to affirmative healthcare, Musk — who, lest w
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Discoveries that could help diabetics titled in honour of activist and journalist murdered in Amazon Scientists in Brazil have found two new species of fermenting yeasts and named them after journalist Dom Phillips and activist Bruno Pereira , the two men murdered last year in the Amazon rainforest. The discovery came from four isolates of the Spathaspora species, according to a paper published i
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A key feature of the severe allergic reaction known as anaphylaxis is an abrupt drop in blood pressure and body temperature, causing people to faint and, if untreated, potentially die. That response has long been attributed to a sudden dilation and leakage of blood vessels. But in a study using mice, researchers have found that this response, especially body temperature drop, requires an additiona
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People are touting AI as a tech that will finally fulfil that long desired dream of freeing people from the drudgery of work. In the past, we were supposedly guaranteed a future where most jobs only required 15 hours a week of work. They wondered what everyone would do with all of their free time. Everything from vacuum cleaners, robotic vacuum cleaners, washing machines, cars, computers, interne
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Breaking: Taylor Swift is not simply a voice in our ears or an abstract concept to argue over at parties, but a flesh-and-blood being with a taste for sparkling pajamas and the stamina of a ram. All concerts are conjurings, turning the audience's idea of a performer into a real thing, but last night's kickoff of Taylor Swift's Eras tour in Glendale, Arizona, heightened the amazement with Houdini-
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Researchers created a system that enables makers to incorporate sensors directly into rotational mechanisms with only one pass in a 3D printer. This gives rotational mechanisms like gearboxes the ability to sense their angular position, rotation speed, and direction of rotation.
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Chatbots and artificial intelligence are increasingly becoming more popular to answer questions about health. Researchers studied one of these resources, ChatGPT, to provide incredibly valuable and well-timed insights into the capabilities and limitations of artificial intelligence in the context of cancer-related information. Are people with cancer and their caregivers getting accurate answers?
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After centuries of distrust and disdain, mushrooms are having their moment. From sci-fi smash hits to drug trials, an emerging league of mycophiles are bringing fungi out of the shadows Get our morning and afternoon news emails , free app or daily news podcast Some people are drawn to beautiful birds. Others are enamoured with orchids. There are those who are mesmerised by the kaleidoscopic swish
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Tyrosine kinase inhibitors (TKI) are employed to attack specific types of cancer cells. The downside to using TKs is that they can cause serious inflammation. A team of researchers has discovered the underlying mechanism that causes this inflammation.
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They are considered the 'Holy Grail' of battery research: so-called 'solid-state batteries'. They no longer have a liquid core, as is the case with today's batteries, but consist of a solid material. This leads to several advantages: Among other things, these batteries are more difficult to ignite and can also be manufactured on a miniature scale. Scientists have now turned their attention to the
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L et us begin with the obvious thing that just happened: This morning, Donald Trump threatened to summon a mob—for the second time in two years—to his defense. The former president of the United States and a leading candidate for the Republican nomination for the White House in 2024, facing a possible indictment in New York, claimed to know the exact day on which he would be arrested and then cal
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It is extremely rare for a new plant species to be discovered in Japan, a nation where flora has been extensively studied and documented. Nevertheless, botanists recently uncovered a stunning new species of orchid whose rosy pink petals bear a striking resemblance to glasswork. Interestingly, it can be found in familiar environments such as lawns and parks, and even in private gardens and on balco
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Tripoli-4® is a tool used by researchers to simulate the behaviors of interacting neutrons in 3D space. Recently, researchers have developed eTLE: a next-event simulator which aims to increase Tripoli-4®'s precision using Monte Carlo simulations. New research implements and validates eTLE's reliability.
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From elephants to tigers, study reveals scale of damage to wildlife caused by transformation of wildernesses and human activity The total weight of Earth's wild land mammals – from elephants to bisons and from deer to tigers – is now less than 10% of the combined tonnage of men, women and children living on the planet. A study by scientists at Israel's Weizmann Institute of Science, published thi
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Most delivery drones look like droids too dumb for Star Wars, or dystopian gnats people want to shoot from the sky — until now. Meet Zipline, the adorable, Jetson-esque delivery drone of your dreams, as debuted today in a series of Tweets on Twitter by its founder. Watch this: 4/ The first innovation is the delivery droid, enabling us to safely deliver into small, protected, (often cluttered!) en
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The best I can come up with the same reason it's hard to proofread your own work. But I'm not convinced this is correct. I asked a similar question on r/MechanicalEngineering – https://www.reddit.com/r/MechanicalEngineering/comments/11rjymu/self_checking_drawing_why_do_we_suck_at_it/?utm_source=share&utm_medium=android_app&utm_name=androidcss&utm_term=1&utm_content=share_button No one had much mo
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Puttin' on the Ritz British luxury carmaker Rolls-Royce just got the go-ahead from the UK government to build a nuclear reactor for a future Moon base. In a press release announcing the decision , the UK Space Agency (UKSA) officially affirmed that Rolls-Royce has been selected as its manufacturer of choice to build a prototypical nuclear reactor for a potential lunar base. Rolls' scientists and
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ARTIFICIAL INTELLIGENCE You Can Now Run a GPT-3-Level AI Model on Your Laptop, Phone, and Raspberry Pi Benj Edwards | Ars Technica "On Friday, a software developer named Georgi Gerganov created a tool called "llama.cpp" that can run Meta's new GPT-3-class AI large language model, LLaMA, locally on a Mac laptop. Soon thereafter, people worked out how to run LLaMA on Windows as well. Then someone s
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Parker helps Tyson weigh out a week's worth of gold in order to predict if he will achieve his goal of 450 pounds. #discoveryplus #goldrush Stream Full Episodes of Gold Rush https://www.discoveryplus.com/show/gold-rush About Gold Rush: Motivated by a depressed economy, hard-working gold miners get to work both in America and across the globe in an attempt to strike it rich. Subscribe to Discovery
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Paradox: Solved Here's a Fermi Paradox solution for you: killer moons are taking out extraterrestrials. We promise it's not as ridiculous as it sounds. According to a new study published in the journal Monthly Notices of the Royal Astronomical Sciences , as spotted by LiveScience , exomoons, or moons that revolve around an exoplanet outside our solar system, could be crashing into their hosts and
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Nature Communications, Published online: 18 March 2023; doi:10.1038/s41467-023-37271-9 The reaction efficiency of reactants near plasmonic nanostructures can be enhanced under illumination. Here, the authors show that the activity of a Co porphyrin molecular catalyst bound to Au nanoparticles is enhanced by plasmonic effects, yielding a high photocatalytic hydrogen generation rate.
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W ould you consider a donation to support Weekend Reads, and our daily work ? The week at Retraction Watch featured: After a sleuth reveals a paper with authorships advertised for sale, it's retracted Here's one article that won't be making any top 50 papers list Gov't committee in Pakistan lets plagiarizing vice-chancellor off the hook When it takes two university-federal agency letters – and fi
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This is an edition of The Wonder Reader, a newsletter in which our editors recommend a set of stories to spark your curiosity and fill you with delight. Sign up here to get it every Saturday morning. In a 1929 Atlantic article titled " Tragedies of Etiquette ," an anonymous writer details the many surprises contained in a book on women's etiquette. One example: "My mother, whom I had always consi
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It doesn't seem fair, does it? Just 15 years after our financial overlords went on a bailout binge, showering bankers with trillions of taxpayer dollars, they're once again riding to the rescue of the rich while the public watches in horror. Did they learn none of the lessons from the 2008 meltdown? Actually, yes, they did. The government's financial-crisis managers clearly studied the lessons of
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The U.S. invasion of Iraq was the most consequential political event of the past two decades. But it doesn't feel that way. It has the faint whiff of youthful indiscretion, an episode that many Americans would rather forget. I was 19. The tenor of that time in American life—after the September 11 attacks—seems ever more foreign to me. Instead of the chaotic information overload of the current mom
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What will be the future of schools with so much technology? Will technology be good or will it get in the way? How is technology in education in your country? submitted by /u/NiS-Kirst [link] [comments]
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How can we prepare ourselves for the ethical, social and economic challenges that the AI/Singularity era might bring? What skills or abilities do you think will be most valuable or essential for humans in the AI/Singularity era? How do you envision the relationship between humans and artificial intelligence in the AI/Singularity era? What are some of the potential benefits or risks of reaching th
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Is it possible with a cognitive science master degree to get a job in the prosthetics field? Especially in the neuroprosthetics field? Is there anyone who works in this field with this degree? I have a special needs education degree in Europe specialised in movement and cognitive therapy, and will start my master in cognitive science. My biggest dream is to work in the prosthetics field and work
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Nature Communications, Published online: 18 March 2023; doi:10.1038/s41467-023-37138-z The authors demonstrate the enhancement of nonlinear optomechanical measurement of mechanical motion by using pairs of coupled optical and mechanical modes in a 1D photonic crystal. The design harnesses the anisotropic mechanical elasticity to create strong coupling between mechanical modes.
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Nature Communications, Published online: 18 March 2023; doi:10.1038/s41467-023-37018-6 Lateral flow assays are valuable rapid diagnostic tests, but low sensitivity can hinder their precision. Here, the authors report an enrichment method using nanoporous AAO and red blood cell membranes, which when applied to patient samples prior to analysis can improve sensitivity up to 20-fold.
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Nature Communications, Published online: 18 March 2023; doi:10.1038/s41467-023-37268-4 Controlling the morphology of Pt-based nanostructures can provide a great opportunity to boost their catalytic activity and durability. Here the authors report anisotropic mesoporous Pt@Pt-skin Pt3Ni core-shell framework nanowires for oxygen reduction reaction with enhanced mass activity and stability.
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Nature Communications, Published online: 18 March 2023; doi:10.1038/s41467-023-37227-z The secretome of hepatocytes and hepatocellular carcinoma (HCC) cells can contribute to cancer progression. Here the authors show that PRSS35 inhibits HCC progression through proteolytic depletion of CXCL2 and subsequently decreased neutrophil recruitment to tumours.
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Nature Communications, Published online: 18 March 2023; doi:10.1038/s41467-023-37157-w Despite increasing interest in organic room temperature phosphorescence, it can still be challenging to determine mechanism and develop practical applications. Here, the authors report room temperature phosphorescent systems from chiral components, with strong phosphorescence observed only when both host and gu
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I'm having trouble deciding between the following schools: Queen's University, Carleton University, and University of British Columbia. Is anyone able to give me some insight into the best uni for cognitive science? UBC doesn't outright offer a degree in cognitive science but they have the "cognitive systems" program which is close enough. Carleton has a Bachelor of Cognitive Science and I believ
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There is a very good short video from VOX talking about the water crisis in America . 6% of our Western US water usage is residential, 8% is commercial, while 86% is from agricultural. There is actually a lot that could be done to reduce agriculture watering waste while actually improving yields. Here's one of my ideas: Remote 3D Printed drip irrigation systems. Drip irrigation can save up to 25-
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More than 85% of the world's bird, mammal, and amphibian species live in mountains, particularly in forest habitats, but researchers report that these forests are disappearing at an accelerating rate. Globally, we have lost 78.1 million hectares (7.1%) of mountain forest since 2000 — an area larger than the size of Texas. Much of the loss occurred in tropical biodiversity hotspots, putting increa
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New research has looked at the long-term environmental impact of different methods to control Japanese knotweed. Different ways of trying to control the invasive species have developed over the years but now, as sustainability becomes increasingly important, understanding the effect of these management methods is vital.This new study examines at the entire life cycle and long-term impacts of diffe
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The ability of a cell to divide, to proliferate, is essential for life and gives rise to the formation of complex organisms from a single cell. It also allows the replacement of used cells from a limited number of 'stem' cells, which then proliferate and specialize. In cancer, however, cell proliferation is no longer controlled and becomes chaotic. Researchers have discovered that, in a healthy in
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This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. Sign up for it here. The critics and the gamers have written much about The Last of Us , the video game that became a majestic HBO series. The main story is about love and family, but there's a dark and nagging question in
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Robo Life Coach How could your employer make your workday less miserable? More breaks, a more reasonable workload, or just a bump in salary? Well, screw all that noise: have some "robot wellbeing coaches" instead. Yes, really: In a series of experiments that involved having wellbeing robots interact with employees in mandatory sessions researchers found that how well a robot boosts employee moral
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Do The Worm America's top minds are apparently putting their all into developing space technology — but we've gotta admit, we wouldn't really have had this in mind. As the Massachusetts Institute of Technology revealed in a blog post , the Walking Oligomeric Robotic Mobility System (WORMS) modular lunar robot is intended to help NASA and other space agencies build and establish permanent Moon col
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A bit of a ridiculous assumption, but something I've thought of for a while now.. Digital Algorithms can successfully predict your purchases on any platform. Before you download anything, it asks if it can access your microphone, camera and internal settings to gain info about yourself. When you talk about food, movies, relationships, plans whether from your voice or what you send in a message, y
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What's that? Sorry, couldn't hear you: I was accessing my home star cluster's dimensional frequency. Oh, it's real: A group of people who — according to TikTok, Instagram, and countless New Age blogs — refer to themselves as " Starseeds ," and believe that they are aliens from different stars and planets, reincarnated inside human bodies. Their valiant task is to help usher in a bountiful golden
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A new NASA mission to Saturn's giant moon, Titan, is due to launch in 2027. When it arrives in the mid-2030s, it will begin a journey of discovery that could bring about a new understanding of the development of life in the universe. This mission, called Dragonfly, will carry an instrument called the Dragonfly Mass Spectrometer (DraMS), designed to help scientists hone in on the chemistry at work
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Without plants, we'd have no air to breathe or food to eat, yet plant science lingers in the shadowy wings while other fields take center stage. With the goal of shining the spotlight on plants, a new study presents the field's top 100 most pressing questions for research to address the greatest challenges facing humanity.
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Leading edge technology has uncovered secrets about a world-renowned fossil hoard that could offer vital clues about early life on earth. Researchers who analysed the 400 million-year-old-cache, found in rural north-east Scotland, say their findings reveal better preservation of the fossils at a molecular level than was previously anticipated.
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Space Goth Grand Slam In an effort to understand the origin of our galaxies, astronomers have spotted an insane, galactic showdown for the ages: four giant black holes in dwarf galaxies destined to collide, though not all in the same place . But boy, did they score a grand slam of astronomy firsts. Using NASA's Chandra X-ray Observatory, the astronomers kept a close eye on two separate pairs of m
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Have you heard? According to some very smart people who did a study (of other studies), the COVID-19 pandemic didn't actually warp everyone's mental health as much as we thought it did! If you're rolling your eyes, you're not alone. Published earlier this month in the British Medical Journal , the meta-analysis looked at 137 studies from (and this is important) mostly-wealthy European and Asian c
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Abstract The histopathologic heterogeneity of intraductal papillary mucinous neoplasms (IPMN) complicates the prediction of pancreatic ductal adenocarcinoma (PDAC) risk. Intratumoral regions of pancreaticobiliary (PB), intestinal (INT), and gastric foveolar (GF) epithelium may occur with either low-grade dysplasia (LGD) or high-grade dysplasia (HGD). We used digital spatial RNA profiling of dyspl
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Abstract HDAC3 is one of the main targets of histone deacetylase (HDAC) inhibitors in clinical development as cancer therapies, yet the in vivo role of HDAC3 in solid tumors is unknown. We identified a critical role for HDAC3 in Kras -mutant lung cancer. Using genetically engineered mouse models (GEMMs), we found that HDAC3 is required for lung tumor growth in vivo. HDAC3 was found to direct and
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Abstract Ventilation in the deep Gulf of Mexico (GoM), its connection to the North Atlantic, and its susceptibility to changes of the Atlantic Meridional Overturning Circulation are investigated by combining observations of radiocarbon and volume transport with a Coupled Model Intercomparison Project phase 6 (CMIP6) General Circulation Model (GCM) ensemble output. Radiocarbon data and multiannual
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Abstract Model-based data analysis of whole-brain dynamics links the observed data to model parameters in a network of neural masses. Recently, studies focused on the role of regional variance of model parameters. Such analyses however necessarily depend on the properties of preselected neural mass model. We introduce a method to infer from the functional data both the neural mass model represent
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Abstract Glass is ubiquitous in life and widely used in various fields. However, there is an urgent need to develop biodegradable and biorecyclable glasses that have a minimal environmental footprint toward a sustainable society and a circular materials economy. Here, we report a family of eco-friendly glasses of biological origin fabricated using biologically derived amino acids or peptides thro
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Abstract The cohesive force of asteroid particles is a crucial parameter in microgravity. The cohesive force was evaluated under the assumptions of lunar regolith and proportionality to particle size; however, it is sensitive to particle shape. In this study, cohesive-force measurements of meteorite fragments and aggregates consisting of silica microspheres revealed that the cohesive force is ind
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Abstract The cointegration of artificial neuronal and synaptic devices with homotypic materials and structures can greatly simplify the fabrication of neuromorphic hardware. We demonstrate experimental realization of vanadium dioxide (VO 2 ) artificial neurons and synapses on the same substrate through selective area carrier doping. By locally configuring pairs of catalytic and inert electrodes t
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Abstract The interleukin-6 (IL-6) family cytokines signal through gp130 receptor homodimerization or heterodimerization with a second signaling receptor and play crucial roles in various cellular processes. We determined cryo–electron microscopy structures of five signaling complexes of this family, containing full receptor ectodomains bound to their respective ligands ciliary neurotrophic factor
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Abstract Future space travel needs ultra-lightweight and robust structural materials that can withstand extreme conditions with multiple entry points to orbit to ensure mission reliability. This is unattainable with current inorganic materials. Ultra-highly stable carbon fiber reinforced polymers (CFRPs) have shown susceptibility to environmental instabilities and electrostatic discharge, thereby
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Abstract Toll/interleukin-1 receptor (TIR) domain proteins function in cell death and immunity. In plants and bacteria, TIR domains are often enzymes that produce isomers of cyclic adenosine 5′-diphosphate–ribose (cADPR) as putative immune signaling molecules. The identity and functional conservation of cADPR isomer signals is unclear. A previous report found that a plant TIR could cross-activate
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Abstract Using genome-wide data of 89 ancient individuals dated to 5100 to 100 years before the present (B.P.) from 29 sites across the Tibetan Plateau, we found plateau-specific ancestry across plateau populations, with substantial genetic structure indicating high differentiation before 2500 B.P. Northeastern plateau populations rapidly showed admixture associated with millet farmers by 4700 B.
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Abstract Proteins can specifically bind to curved membranes through curvature-induced hydrophobic lipid packing defects. The chemical diversity among such curvature "sensors" challenges our understanding of how they differ from general membrane "binders" that bind without curvature selectivity. Here, we combine an evolutionary algorithm with coarse-grained molecular dynamics simulations (Evo-MD)
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Abstract Despite the fact that oral microecologics are effective in modulating the gut microbiome, they always suffer from multiple insults during the journey from manufacture to arrival at the intestine. Inspired by the protective mechanism of mineralization, we describe a cytocompatible approach of biointerface mineralization that can generate an ultraresistant and self-removable coating on bac
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The microbes that inhabit the gut are critical for human health, and understanding the factors that encourage the growth of beneficial bacterial species—known as "good" bacteria—in the gut may enable medical interventions that promote gut and overall human health. In a new study, Yale researchers have uncovered a novel mechanism by which these bacteria colonize the gut.
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Scientists from Uppsala University have used cryo-electron microscopy to reveal details of the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrheic disease. The new insights could be valuable for screening specific drugs against Giardia and other protozoan parasites.
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Singular Concern In an editorial that operates more as a stark warning than an explainer, a pair of philosophers sounded the alarm on the dystopian future they see being ushered in by brain-computer interface (BCI) technology. Writing for The Conversation , University of New England philosophers Sandy Boucher and John Kendall Hawkins said that we're rapidly approaching what's known as "the singul
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Logo-rithmic The Canadian Space Agency issued a press release about their newly-updated logo. That said, it's pretty clear to even the most casual viewer that it's aboot as Canadian as Drake riding a moose wearing a Raptors jersey. Which is to say: Very. "The maple leaf generates pride and a sense of belonging, and is also recognized all over the world," the statement reads, bringing to mind the
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The microbes that inhabit the gut are critical for human health, and understanding the factors that encourage the growth of beneficial bacterial species—known as "good" bacteria—in the gut may enable medical interventions that promote gut and overall human health. In a new study, Yale researchers have uncovered a novel mechanism by which these bacteria colonize the gut.
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Interest in the exploration of Venus has kicked up a notch lately, especially after a contested recent discovery of phosphine, a potential biosignature, in the planet's atmosphere. Plenty of missions to Venus have been proposed, and NASA and ESA have recently funded several. However, they are mainly orbiters, trying to peer into the planet's interior from above. But they are challenged by having t
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Accurately reconstructing how the parts of a complex molecular are held together knowing only how the molecule distorts and breaks up—this was the challenge taken on by a research team led by SISSA's Cristian Micheletti and recently published on Physical Review Letters. In particular, the scientists studied how a DNA double helix unzips when translocated at high velocity through a nanopore, recons
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The body pigmentation of an organism is caused by coloring substances and structures that are found in the cells of skin, hair, feathers, or scales, for example. This pigmentation considerably limits investigations of important processes within a living organism (in vivo). To provide a detailed view into the living body, scientists have used transparent model organisms.
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Publishing in the International Journal of Extreme Manufacturing , researchers from Harbin Institute of Technology, Huazhong University of Science and Technology, Guizhou University and Ruhr-University Bochum present a brief review on the application of numerical simulations in addressing the impact of properties and microstructures of workpiece materials on the diamond cutting mechanisms of diffe
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The Tibetan Plateau, the highest and largest plateau above sea level, is one of the harshest environments settled by humans. It has a cold and arid environment and its elevation often surpasses 4000 meters above sea level (masl). The plateau covers a wide expanse of Asia—approximately 2.5 million square kilometers—and is home to over 7 million people, primarily belonging to the Tibetan and Sherpa
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When do we define a piece of nature in the city as a park? And when is something a tree or shrub? It may seem obvious, but in scientific literature the definitions vary quite a bit. That makes comparisons difficult. Environmental scientist Joeri Morpurgo looked at the differences and designed a general classification system for urban green space.
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This is an edition of Up for Debate, a newsletter by Conor Friedersdorf. On Wednesdays, he rounds up timely conversations and solicits reader responses to one thought-provoking question. Later, he publishes some thoughtful replies. Sign up for the newsletter here. Last week I asked for readers' reflections on the automobile. I wanted to know: How have cars shaped your life? What do you think abou
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By this point, the many defects of AI-based language models have been analyzed to death—their incorrigible dishonesty, their capacity for bias and bigotry, their lack of common sense. GPT-4, the newest and most advanced such model yet, is already being subjected to the same scrutiny, and it still seems to misfire in pretty much all the ways earlier models did. But large language models have anoth
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The body pigmentation of an organism is caused by coloring substances and structures that are found in the cells of skin, hair, feathers, or scales, for example. This pigmentation considerably limits investigations of important processes within a living organism (in vivo). To provide a detailed view into the living body, scientists have used transparent model organisms.
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The Tibetan Plateau, the highest and largest plateau above sea level, is one of the harshest environments settled by humans. It has a cold and arid environment and its elevation often surpasses 4000 meters above sea level (masl). The plateau covers a wide expanse of Asia—approximately 2.5 million square kilometers—and is home to over 7 million people, primarily belonging to the Tibetan and Sherpa
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https://medium.com/@SPX701/march-2023-tech-roundup-the-latest-news-and-innovations-b611f3ca7663 The beginning of March 2023 has witnessed a flurry of exciting news in the field of science and technology. Researchers and scientists from around the world have been hard at work, making discoveries and advancements that promise to reshape the world we live in submitted by /u/BalanceElectronic176 [lin
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Im currently in 11th grade, and Ive been wanting to get a job in the coding field since 2020. But gpt4 https://www.youtube.com/watch?v=OisS1dKd7LU can basically code an entire website in 1 minute just by 1 picture. If this is only gpt4, what if gpt7 comes out in 5-6 years? If ai progressed this much from 2022 to 2023, imagine how advanced it could be in years in the future? If this ai can already
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Old Data, New Find Venus is back, baby — and very much alive. Scientists taking a look at old data from NASA's long retired Magellan spacecraft have spotted the best evidence yet that the planet still stirs with volcanic activity, according to a new study published in the journal Science . Two separate photos, taken eight months apart by Magellan in the 1990s, reveal the way a circular volcanic v
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Cast your mind back to the spring of 2020, when grocery store shelves sat bare of essential items and ingredients. For birds who live in the forests of Central America, replacement of forest land with coffee plantations essentially "clears out the shelves" of their preferred foods, causing them to shift their diets and habitats to survive.
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For more than six decades, Alaska's North Slope has been a focus of intense controversy over oil development and wilderness protection, with no end in sight. Willow field, a 600-million-barrel, US$8 billion oil project recently approved by the Biden administration—to the outrage of environmental and climate activists—is the latest chapter in that long saga.
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Abruptly melting ice sheets, the collapse of coral reefs and rainforests: nature is complex—and climate policy must consider physical "tipping points" as well as uncertainties and measurement problems. How can the fight against the greenhouse effect be shaped, given that the world is not as simple as a greenhouse?
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Have you ever wondered if social factors like pandemics can affect UFO reporting? In a recent article published in the Journal of Scientific Exploration, authors Chase Cockrell from the University of Vermont, and Mark Rodeghier and Linda Murphy from the Center for UFO Studies, investigated whether the COVID-19 pandemic was associated with an increase in UFO sightings.
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The 2013-2016 marine heat wave known as "The Blob" warmed a vast expanse of surface waters across the northeastern Pacific, disrupting West Coast marine ecosystems, depressing salmon returns, and damaging commercial fisheries. It also prompted a wave of research on extreme warming of ocean surface waters.
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A startup co-founded by a SpaceX alum, plans to jumpstart the future of space manufacturing with its orbital pharmaceutical lab — which will be run by robots. As Bloomberg notes in a profile on the Los Angeles-based Varda Space Industries, the biggest thing going for Varda's gambit is the fact that in microgravity, atoms, and molecules behave differently. That's why space-bound manufacturing pres
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Fistful of Samurai Swords Thanks to a recent study , scientists can confirm that the Therizinosaurus, a therapod that according to Live Science lived during the Late Triassic and Cretaceous periods roughly 220 to 66 million years ago, was a much gentler giant than previously thought — despite the fact that it could grow up to 40 feet in length and had, well, terrifying three-foot-long claws on ea
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Dark Web Is having internet access everywhere in the world always a good thing? On one hand, sure, there's a humanitarian case for it. On the other? Look no further than Elon Musk's satellite-powered internet Starlink becoming the preferred internet provider of * checks notes * illegal Brazilian mining operations in the Amazon, according to a new, slightly surreal Associated Press report . In a T
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Middle school is a time like no other, as significant biological and emotional changes coincide with profound personal growth, says educator Jerome Hunter. The middle school for boys that he founded centers on a program that helps redefine masculinity through what he calls the three "Cs" — confidence, communication and community. He shares the growth he's seen when boys are encouraged to explore
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Spring brings warmer weather, blooming flowers and the unfortunate re-emergence of the spotted lanternfly, a prolific invasive insect reviled for the havoc it wreaks on forests and cropland. Today, you may see egg masses—be sure to remove them if you do—and soon the nymphs will hatch across the mid-Atlantic. Arriving from Asia, spotted lanternflies were first detected in Pennsylvania in 2014 and s
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Without water, life on Earth could not exist as it does today. Understanding the history of water in the universe is critical to understanding how planets like Earth come to be. Astronomers typically refer to the journey water takes from its formation as individual molecules in space to its resting place on the surfaces of planets as "the water trail." The trail starts in the interstellar medium
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Spring brings warmer weather, blooming flowers and the unfortunate re-emergence of the spotted lanternfly, a prolific invasive insect reviled for the havoc it wreaks on forests and cropland. Today, you may see egg masses—be sure to remove them if you do—and soon the nymphs will hatch across the mid-Atlantic. Arriving from Asia, spotted lanternflies were first detected in Pennsylvania in 2014 and s
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More than 85% of the world's bird, mammal, and amphibian species live in mountains, particularly in forest habitats, but researchers report in the journal One Earth on March 17 that these forests are disappearing at an accelerating rate. Globally, we have lost 78.1 million hectares (7.1%) of mountain forest since 2000—an area larger than the size of Texas. Much of the loss occurred in tropical bio
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The livelihoods of millions of people who live in river deltas, among the world's most productive lands, are at risk. Created where large rivers meet the ocean and deposit their natural sediment load, river deltas are often just a few meters above sea level. And while they make up less than 0.5% of the world's land area, river deltas contribute more than 4% of the global GDP, 3% of global crop pro
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A report released today by the UC Berkeley Labor Center finds that many workers essential to keeping the state running and providing crucial services are struggling to make ends meet. Ensuring a living wage to government workers is critical to helping the state recover from the economic and social impacts of the COVID-19 pandemic.
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Our audience research team would like to hear from our newsletter readers. To share feedback on The Books Briefing, please fill out this survey . There are a few good books I'd happily reread until the spine splits. Autobiography of Red , by Anne Carson, is one: I can flip to any page and immediately sink back into the odd, lush world of her red-faced monster, Geryon. The first time I read it, I
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I have seen enough to know that it's going to alter our lives. Just think what AI tools could do when used by creative people in fashion or architecture The recent flurry, or rather blizzard, of announcements of new variants of generative AI have brought a storm of hype and fright. OpenAI's ChatGPT already appeared to be a gamechanger , but now this week's new version, GPT-4 , is another leap ahe
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Analysis of gene sequences by international team finds Covid-positive samples rich in raccoon dog DNA Newly released genetic data gathered from a live food market in Wuhan has linked Covid-19 with raccoon dogs, adding weight to the theory that infected animals sold at the site started the coronavirus pandemic, researchers involved in the work say. Swabs collected from stalls at the Huanan seafood
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Researchers believe UK prevalence of peanut allergies could fall by 77% if eaten from four to six months of age Peanut products such as puffed snacks and peanut butter should be given to children from four to six months of age to reduce the risk of them developing a peanut allergy, experts have said. Studies suggest the prevalence of peanut allergy among children in western countries has doubled
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A majority of people radicalized to hold extremist views needed mental health services that they hadn't previously received, research in Canada finds. Ottawa brings home and reintegrates women detained in Syria after travelling to join the Islamic State. At the same time, a surge in far-right movements has become a top concern for Canadian national security. The new study in the International Jou
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The James Webb Space Telescope (JWST) is set to transform astronomers' understanding of the chemistry of newly formed stars, with an analysis by RIKEN researchers of early results showing that it can detect complex organic molecules in the clouds of gas and ice surrounding a newborn star.
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-37156-x Engineering excitation wavelength of photosensitizers allows to enhanced reactive oxygen species but controlling the wavelength corresponding to operating conditions remains challenging. Here, the authors implement a wavelength-engineerable imidazolium-based porous organic polymer and demonstrate tuning of the
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-37175-8 Hypomethylating agents, such as 5-Azacytidine (5-AZA), are standard of care for patients with myelodysplastic and myeloid malignancies, however response rates are limited and risk of relapses high. Here the authors show that inhibition of lysyl oxidases synergizes with 5-AZA to improve erythropoiesis and reduce
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-36941-y Neutrophilic inflammation is a hallmark of many monogenic autoinflammatory diseases. Here the authors report a case series of three unrelated boys with perinatal-onset of neutrophilic cutaneous small vessel vasculitis and systemic inflammation, and identify de novo truncating and missense variants in the Src-fa
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Regeneron Pharmaceuticals, a biotechnology company that develops life-transforming medicines, found itself inundated with vast volumes of data during the peak of the covid-19 pandemic. In order to derive actionable information from these disparate data sets, which ranged from clinical trial data to real-time supply chain information, the company needed new ways to join and relate them, regardless
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Wild populations of the common morning glory in the southeastern United States increased the size of their flowers between 2003 and 2012, according to a new study. There's been a well-documented shift toward earlier springtime flowering in many plants as the world warms. The trend alarms biologists because it has the potential to disrupt carefully choreographed interactions between plants and the
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A NASA rocket team is on the hunt for giant hurricane-like swirls in our upper atmosphere. These swirls, or vortices, may be key to upper atmospheric weather patterns that affect the entire globe. The Vorticity Experiment, or VortEx mission, is readying for a launch on March 17, 2023, from the Andøya Space Center in Andenes, Norway.
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The "Flash Joule" technique could be a profitable way to turn plastic waste into nanomaterials, report researchers. The amount of plastic waste produced globally has doubled over the past two decades—and plastic production is expected to triple by 2050—with most of it ending up in landfills, incinerated, or otherwise mismanaged, according to the Organization for Economic Cooperation and Developme
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Rho GTPases have a crucial role in the orchestration of cell movements. Cells use Rho GTPases to coordinate cytoskeletal reorganization in dynamically changing environments. Among these RhoGTPases, Cdc42 and Rac1 promote cytoskeletal formation, whereas RhoA is involved in myosin II-mediated cytoskeletal retraction and formation.
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Evolutionary biologists aim to form fundamental connections between microevolutionary processes and macroevolutionary patterns based on comparative datasets of population-level variation. In a new report on Science Advances, Daniel R. Rhoda and a team of scientists in evolutionary biology at the University of Chicago and the Jackson Laboratory in the U.S., analyzed a previously published dataset o
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A trio of evolutionary biologists, two with Carleton University, the other with Seoul National University, has apparently solved the paradox of aposematism—how animals managed to evolve with bright colors to warn predators of their toxic nature. In their paper study, published in the journal Science, Karl Loeffler-Henry, Changku Kang and Thomas Sherratt, conducted an analysis of the family tree of
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Evolutionary biologists aim to form fundamental connections between microevolutionary processes and macroevolutionary patterns based on comparative datasets of population-level variation. In a new report on Science Advances, Daniel R. Rhoda and a team of scientists in evolutionary biology at the University of Chicago and the Jackson Laboratory in the U.S., analyzed a previously published dataset o
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A trio of evolutionary biologists, two with Carleton University, the other with Seoul National University, has apparently solved the paradox of aposematism—how animals managed to evolve with bright colors to warn predators of their toxic nature. In their paper study, published in the journal Science, Karl Loeffler-Henry, Changku Kang and Thomas Sherratt, conducted an analysis of the family tree of
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To me, progress in medicine is agonizingly slow. The main issue seems to be that any clinical trial has to involve human testing at some point, which introduces both ethical constraints and incompressible time constraints (when studying the effect of a drug on a population over 5 years for instance).The human body is extremely complex, presently we can't even measure everything that needs to be m
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People living in the United States must travel significantly farther to access methadone treatment for opioid addiction than Canadians do, research indicates. As reported in the journal Drug and Alcohol Dependence , the analysis shows that the average driving distance to the closest methadone clinic accepting new patients was more than three times greater in the US than in Canada. When limiting t
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Non-native animals can't replace the originals on the island of Mauritius, research finds. If the extinction of the many plants and animals on Mauritius continues, the flourishing nature and diverse animals may dwindle to very few. They are part of a particularly sensitive ecosystem where animals help plants spread their seeds . If the animals disappear or are replaced by other species, the seeds
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When shopping online, most consumers are drawn to products with a high star rating. Not only are star ratings an easy way for past buyers to assess purchases, they also provide a visual marker that helps potential buyers quickly sort through various options. Quantitative star ratings have long been known to positively affect consumer demand for a product, but less is known about qualitative text (
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Researchers from the Universidad de Santiago de Chile and the University of Notre Dame, working with machine learning, have devised a method to identify organic compounds based on the refractive index at a single optical wavelength. The technique could have research and industrial applications for automated chemical analysis that is cheaper, safer and requires less expertise to operate.
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Raised in Hertfordshire and encouraged to think big from an early age, Fox is only second woman to hold the post Women should never be afraid to ask questions, says Nicola Fox, Nasa's new science chief and only the second woman to hold this position in the agency's history. In her view, being curious and having a ton of questions are the hallmarks of a successful scientist – even if asking them c
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This is today's edition of The Download , our weekday newsletter that provides a daily dose of what's going on in the world of technology. Chinese tech giant Baidu just released its answer to ChatGPT Yesterday, Robin Li, Baidu's cofounder and CEO, took the stage in Beijing to showcase the company's new large language model, Ernie Bot. He showed off pre-recorded examples of what the chatbot can do
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-37187-4 Skin-nerve crosstalk is a major element of skin physiological pathology. Here the authors report a 3D innervated epidermal keratinocyte layer as a sensory neuron-epidermal keratinocyte coculture model on a microfluidic chip using the slope-based air-liquid interfacing culture and spatial compartmentalization.
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Ny version af Open AI's sprogmodel skuffer. Til gengæld er dokumentationen en black box, som du kan høre i denne uges udgave af Transformator, hvor du også kan høre, hvordan antibiotika blev forurenet med resistente bakterier, og hvor meget TikTok ved om sine brugere.
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The nuclear debate seems never-ending, which I guess is to be expected. Every large technology has tradeoffs. But the need to transition our energy infrastructure to carbon neutral has shifted the equation, and it is now arguable that we cannot afford to ignore the option of nuclear energy. The UK seems to agree with this take – they currently generate about 15.5% of their energy through nuclear
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The collapses of Silicon Valley Bank and Signature Bank this past weekend were the end point in an all-too-familiar cycle: first the boom, then the breathtakingly speedy bust, and then the bailout. We are now at the postmortem moment—when everyone wonders where the regulators were. Silicon Valley Bank has already become notorious for how obvious its red flags were. Perhaps the most telling was th
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Updated at 11:58 a.m. ET on March 17, 2023 As I was preparing to go onstage for an event recently, the moderator warned my co-panelist and me that the very first prompt would be "Please define the word woke for the audience." We all sighed and laughed. It's a fraught task, requiring qualification and nuance, because woke has acquired what the French philosopher Raymond Aron termed "subtle," or "e
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De snabbt ökande matpriserna gräver hål i konsumenternas plånböcker och eldar på inflationen. Men är situationen värre i Sverige än i andra europeiska länder? Svaret är att variationer finns över tid, men i stort sett följer de svenska priserna EU-snittet. Inlägget dök först upp på forskning.se .
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All the Spiranthes on the Japanese mainland were thought to be a single species, but in fact there are two In Japan, a country with a rich and ancient history of horticulture, it is nowadays extremely rare for a new plant species to be identified. But the latest one has been growing under their noses, and it is exceptionally beautiful. Spiranthes hachijoensis , whose rosy pink petals bear a strik
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It is extremely rare for a new plant species to be discovered in Japan, a nation where flora has been extensively studied and documented. Nevertheless, Professor Suetsugu Kenji and his associates have recently uncovered a stunning new species of orchid whose rosy pink petals bear a striking resemblance to glasswork.
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This article is from The Checkup, MIT Technology Review's weekly biotech newsletter. To receive it in your inbox every Thursday, sign up here . Earlier this week, I had a fascinating call with Nita Farahany, a futurist and legal ethicist at Duke University in Durham, North Carolina. Farahany has spent much of her career exploring the impacts of new technologies—in particular, those that attempt t
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Control of the House of Representatives could teeter precariously for years as each party consolidates its dominance over mirror-image demographic strongholds. That's the clearest conclusion of a new analysis of the demographic and economic characteristics of all 435 congressional districts, conducted by the Equity Research Institute at the University of Southern California in conjunction with Th
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Män som spelade fotboll i allsvenskan fram till mitten av 1900-talet drabbades oftare av demens, jämfört med övriga befolkningen. Nickar och huvudkollisioner kan vara förklaringen, menar forskarna bakom en ny studie. Inlägget dök först upp på forskning.se .
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Janine McCarthy Public attention to the use of animals in research is on the rise, and with good reason. As scientists, we have a responsibility to avoid using animals in our work whenever possible. Not only does this prevent needless suffering and waste of resources, it also leads to better science, because findings from animal experiments often fail to hold up in humans. If studies can be condu
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-37149-w A recent study from Nature Communications reveals that Mycobacterium tuberculosis can hijack epigenetic machinery in host cells and induce host cell ferroptosis, which promotes pathogen pathogenicity and spread. These findings also suggest new therapeutic strategies to treat tuberculosis.
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-36925-y Multicellular fungi have septal pores that allow cytoplasmic exchange between adjacent cells; cell wounding and other stress conditions induce septal pore closure. Here, Mamun et al. determine the subcellular localization of hundreds of uncharacterized proteins in a multicellular fungus, identifying 62 proteins
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Cyclic peptides often exhibit low membrane permeability that can be significantly improved via amide-to-ester substitutions, as demonstrated by researchers from Tokyo Institute of Technology (Tokyo Tech). The utilization of substitutions shown in a new study can be used to develop cyclic peptides with high membrane permeability and oral bioavailability for clinical and therapeutic applications.
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Cyclic peptides often exhibit low membrane permeability that can be significantly improved via amide-to-ester substitutions, as demonstrated by researchers from Tokyo Institute of Technology (Tokyo Tech). The utilization of substitutions shown in a new study can be used to develop cyclic peptides with high membrane permeability and oral bioavailability for clinical and therapeutic applications.
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In a few years from now we may be at the point where with some combination of ChatGPT and Midjourney content creators of all types will be able to produce audio and video content that appears so real but never actually happened. What happens in aftermath of such a possibility? Do all content creators just essentially quit and use AI to produce new content? For content creators who would still pro
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I believe mundane and repetitive jobs like dock workers, burger flippers, garbage man, etc are the only future proof job. All these take place in the real physical world, and the real world is a chaotic mess. The cost of building an robot is insanely prohibitive and they are still limited to specific tasks, while humans on the other hand are versatile. Humans can juggle different tasks and adapt
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-37178-5 Dielectric elastomers (DEs) are widely used in soft actuators but existing DE actuators often require high driving electrical fields. Here the authors demonstrate that introducing cyanoethyl cellulose into plasticized PVC gel confers high dielectric permittivity and allows the fabrication of elastomer actuators
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One mudslide after another finally destroyed the house of Elvis Palomino in Chaclacayo, east of Peru's capital Lima, where others are stacking sandbags they hope will save them from a similar fate.
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Bacteria are literally everywhere—in oceans, in soils, in extreme environments like hot springs, and even alongside and inside other organisms including humans. They're nearly invisible, yet they play a big role in almost every facet of life on Earth.
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Exclusive: rare purple organism preys on trapdoor spider in behaviour reminiscent of its 'zombie' relatives that feature in apocalyptic TV show The Last of Us Scientists believe they have discovered a new parasitic fungus which preys on trapdoor spiders in Brazil's Atlantic rainforest. The rare organism, which is purple, belongs to a group of fungi that infect invertebrates and take over the host
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-37228-y Usually, observation of quantum interference in a non-local scenario (that is, when Alice's measurement settings and Bob's outcomes are space-like separated) relies on entanglement. Here, the authors experimentally show four-photon frustrated interference originating from the sources' indistinguishability, with
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In "The Devil's Element," a cautionary study of phosphorus, journalist Dan Egan shows how an element that is essential to maintaining life has become a global menace through it use — and overuse — as a key component of agricultural fertilizers. Recently, the toxic consequences have re-emerged: algae blooms.
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-37261-x The working temperature of boron-based catalysts reduces their thermodynamic advantages in the oxidative dehydrogenation of propane (ODHP). Here the authors demonstrate encapsulated Ni nanoparticles as effective subsurface promoters to enhance the low temperature activity and selectivity of the boron oxide over
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No matter how bad I feel, I have to remind myself that the treatment is working to reduce my tumour Nausea, diarrhoea, joint pain, fatigue, hair loss – the list of side-effects for most cancer drugs reads like symptoms of many illnesses in their own right. Before I had this disease, I would have considered making a GP appointment if I'd been suffering just some of the problems that I later came t
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My brain is melting recently with all these chat gpt, image generator and ml/ai stuffs , and there is one huge problem that is bugging me and I dont think people are disccusing it enough. Is there any rule around people claiming that a pure ai generated work is human generated. Lets say, I voice clone someone else and claim it as my real voice, I generated a whole book and say that I wrote it in
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-37188-3 Spatial analysis of microbiomes at single cell resolution is challenging. Here the authors report a highly multiplexed method for spatial profiling, sequential error-robust fluorescence in situ hybridisation (SEER-FISH), and show that this allows mapping of microbial communities at micron-scale.
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-37057-z Congenital limb defects are often associated with genomic rearrangements. Here they provide insights into the molecular mechanism underlying SHFM3-associated structural variations, offering a conceptual framework for how genomic rearrangements can alter gene expression and cause disease.
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-37119-2 Inspired by semi-aquatic animals, such as water striders and fisher spiders, that can exhibit a unique locomotion mechanism involving jumping on water, the authors find the scale dependency of water jumping performance and verify it with a theoretical model and robots with improved jumping performance.
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Nature Communications, Published online: 17 March 2023; doi:10.1038/s41467-023-37209-1 This study characterizes expression of pharmacogenes across the histological NAFLD severity spectrum. Here, the authors show the downregulation of CYP2C19 in NAFLD which supports developing personalized medicine approaches for drugs sensitive to metabolism by the CYP2C19 enzyme.
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In light of recent environmental catastrophes, it is apparent now more than ever before that we all must begin collaborating to find solutions to the pollution that disrupts every single ecosystem on Earth. If we don't drastically reduce & reverse pollution, we could start to witness the collapse of crucial ecosystems that allow for us to exist. Can somebody smarter than me tell us how to begin t
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Mutation likely to have come from a founder individual from the island who lived at least 250 years ago One in a hundred people with Orkney heritage have a gene mutation that increases the risk of breast and ovarian cancer, according to a study. Researchers spotted the gene variant repeatedly in women from the archipelago off the north-eastern coast of Scotland who had the cancers, and clinical g
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A new process that lets scientists chemically cut apart and stitch together nanoscopic layers of two-dimensional materials — like a tailor altering a suit — could be just the tool for designing the technology of a sustainable energy future. Researchers have developed a method for structurally splitting, editing and reconstituting layered materials, called MAX phases and MXenes, with the potentia
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This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. Sign up for it here. Both Donald Trump and Ron DeSantis have signaled their willingness to sell out Ukraine to the Kremlin, and the Russians have gleefully taken notice. How could this be happening in the party of Ronald R
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A new approach that delivers a 'one-two punch' to help T cells attack solid tumors is the focus of a preclinical study. The findings showed that targeting two regulators that control gene functions related to inflammation led to at least 10 times greater T cell expansion in models, resulting in increased anti-tumor immune activity and durability.
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Editor's note: This is a translation of a story about how the crime-tracking app Citizen has been giving away free subscriptions to elderly Asians in the Bay Area. Find the English language version here . 本文是与普利策中心的人工智能问责网络合作撰写的。 当外面天黑的时候,约瑟芬·赵(Josephine Zhao)哪怕只是走几个街区就能回到旧金山的家,有时也会多叫一双"眼睛"——字面意义的眼睛。 赵打开手机上的Citizen App,通过一个名为"实时监控"的功能,与该平台的一个客服人员建立联系。而该平台也可以通过网络追踪到赵的GPS位置,客服只要点击另一个按钮,就可以得到打开她手机摄像
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Updated at 9:51 a.m. ET on March 17, 2023 For three years now, the debate over the origins of the coronavirus pandemic has ping-ponged between two big ideas: that SARS-CoV-2 spilled into human populations directly from a wild-animal source, and that the pathogen leaked from a lab. Through a swirl of data obfuscation by Chinese authorities and politicalization within the United States, and rampant
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GPT-4 is here , and you've probably heard a good bit about it already. It's a smarter, faster, more powerful engine for AI programs such as ChatGPT. It can turn a hand-sketched design into a functional website and help with your taxes. It got a 5 on the AP Art History test. There were already fears about AI coming for white-collar work , disrupting education , and so much else , and there was som
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On Thursday, Robin Li, Baidu's cofounder and CEO, took the stage in Beijing to showcase the company's new large language model, Ernie Bot. Accompanied by art created by Baidu's image-making AI, he showed examples of what the chatbot can do, including solve math questions, write marketing copy, answer questions about Chinese literature, and generate multimedia responses. Baidu had planned for this
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Do certain sounds really bother you? Do you experience ASMR? Do you experience musical chills? If so, we want to study you! The UNLV Music Lab (Principal Investigator: Erin Hannon) is conducting a new study about misophonia, ASMR, musicality and emotional responses to meaningful sounds. We are currently recruiting for a research study in which we will ask you questions about which sounds you like
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Most cities don't map their own pedestrian networks. Now, researchers have built the first open-source tool to let planners do just that. Researchers have built TILE2NET, an open-source tool that uses aerial imagery and image-recognition to create complete maps of sidewalks and crosswalks. The tool can help planners, policymakers, and urbanists who want to expand pedestrian infrastructure.
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An increasing number of U.S. interstates are set to try out an invention that could save millions of taxpayer dollars and significantly reduce traffic delays. The invention, a sensor that allows concrete to 'talk,' decreases construction time and how often concrete pavement needs repairs while also improving the road's sustainability and cutting its carbon footprint. Embedded directly into a concr
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In a Phase II trial, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC). New findings from the NEOSTAR trial, published today in Nature Medicine, provide further support for neoadjuvant immunothera
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Intense fishing and over-exploitation have led to evolutionary changes in fish stocks like cod, reducing both their productivity and value on the market. These changes can be reversed by more sustainable and far-sighted fisheries management. A new study shows that reversal of evolutionary change would only slightly reduce the profit of fishing, but would help regain and conserve natural genetic di
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Fuel For Thought The US military has released a dramatic video of a mid-air exchange between an American drone and a Russian fighter jet that first doused the drone in jet fuel before colliding with it. As CNN and other outlets report, the aircraft altercation occurred earlier this week above the Black Sea in Eastern Europe. According to officials, the entire encounter — which is the first time U
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More than a third of FDA-approved drugs work by targeting a G protein-coupled receptor, or GPCR. The human body has more than 800 types of GPCRs that provide cells with information about the external environment to calibrate responses. Drugs that either block or activate GPCRs are used to treat a wide range of diseases including hypertension, pain and inflammation. Most drugs bind to the outside o
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As part of a new NASA Quantum Pathways Institute consisting of a multi-university research team, UC Santa Barbara professor of electrical and computer engineering Daniel Blumenthal will help to build technology and tools to improve measurement of important climate factors by observing atoms in outer space.
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More than a third of FDA-approved drugs work by targeting a G protein-coupled receptor, or GPCR. The human body has more than 800 types of GPCRs that provide cells with information about the external environment to calibrate responses. Drugs that either block or activate GPCRs are used to treat a wide range of diseases including hypertension, pain and inflammation. Most drugs bind to the outside o
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Compass readings that do not show the direction of true north and interference with the operations of satellites are a few of the problems caused by peculiarities of the Earth's magnetic field. The magnetic field radiates around the world and far into space, but it is set by processes that happen deep within the Earth's core, where temperatures exceed 5,000-degrees C. New research from geophysicis
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Researchers have shown how energy disappears in quantum turbulence, paving the way for a better understanding of turbulence in scales ranging from the microscopic to the planetary. The team's findings demonstrate a new understanding of how wave-like motion transfers energy from macroscopic to microscopic length scales, and their results confirm a theoretical prediction about how the energy is diss
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Solar cells made from metal halide perovskites achieve high efficiencies and their production from liquid inks requires only a small amount of energy. Scientists are investigating the production process. At the X-ray source BESSY II, the group has analyzed the optimal composition of precursor inks for the production of high-quality FAPbI3 perovskite thin films by slot-die coating. The solar cells
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O n a warm , windy fall night in Los Angeles, I stood in a conference room at the Warner Bros. Discovery television-production offices, straightened my spine, and stared down my showrunner, preparing to defend my idea for a minor character in our near-future science-fiction series. "This character needs a backstory, and switching jobs because she wants to work in renewable energy and not for an o
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Using a new computational approach they developed to analyze large genetic datasets from rare disease cohorts, researchers at the Icahn School of Medicine at Mount Sinai and colleagues have discovered previously unknown genetic causes of three rare conditions: primary lymphedema (characterized by tissue swelling), thoracic aortic aneurysm disease, and congenital deafness.
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Passion fruit has become an important fruit crop in Taiwan and Southeast Asia due to its special taste and nutrient-rich flesh. However, it is seriously harmed by viruses, blight, and brown spot diseases. As a result of virus disease, producers have to renew passion fruit plantlets every year to ensure yield and fruit quality.
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Clippy on Steroids You can run, but you can't hide — AI is coming for your office work. All of it. Still riding high on the success of integrating ChatGPT in Bing, Microsoft just announced that its GPT-4-powered Copilot is coming to Office 365 apps. With it, users will be able to generate entire Word documents, Excel spreadsheets, Outlook emails, and PowerPoint presentations with a click of a but
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Auto-Dating As if dating apps aren't horrific enough , supposed ex-Tinder employees have created an especially ghoulish app called CupidBots, Vice reports , and it wants to completely automate the dating process. Even worse, their ideal users are — and this is real — men either too pathetic or too lazy to ask a woman out. Now, guys with zero game can try their luck with CupidBots. For $15 a month
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In organic solar cells, carbon-based polymers convert light into charges that are passed to an acceptor. This type of material has great potential, but to unlock this, a better understanding is needed of the way in which charges are produced and transported along the polymers.
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A small nucleus in the brainstem called locus coeruleus (literally the 'blue spot,') is the primary source of a major neuromodulator, norepinephrine (NE), an important mediator of the 'fight or flight' response in animals. However, very little is known about the local connections of this small albeit critically important group of neurons. A recent pioneering study now reveals the cellular composit
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John Wick has never really been a chatty fella. The character's one big monologue in the first Wick film comes as even more of a shock than his ability to mow down dozens of gangsters while armed with just a pistol and his wits. With the upcoming release of John Wick: Chapter 4 , Keanu Reeves has now spent nine years playing the quasi-mute bogeyman di tutti bogeymen, the scariest assassin in a wo
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Last Thursday night, the sirens started wailing in Tel Aviv, the telltale sign of an attack. My first thought was Please, God, let it be a terrorist. Better the familiar trauma of Palestinian terror than the novel horror of Jews shooting at Jews, igniting civil war. Because such a nightmare these days indeed seems conceivable. Hundreds of thousands of Israelis take to the streets on a nightly bas
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