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Nyheder2018november20

 

Ecstacy makes people cooperative, but not gullible

New research has found that MDMA, the main ingredient in ecstasy, causes people to cooperate better — but only with trustworthy people. In the first study to look in detail at how MDMA impacts cooperative behavior the researchers also identified changes to activity in brain regions linked to social processing.

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Mite genomes reveal 'mighty surprising' fragrant and colorful secrets

Scientists have uncovered some unexpected 'foreign' genes in the tiny itch-inducing chigger mite and its more benign but enormous cousin, the giant velvet mite. Genome sequencing of these mites, both members of the trombidid mite family, reveals them to have functional genes for producing terpenes — naturally occurring and often fragrant compounds that are commonly found in plants, but extremely

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Making X-ray microscopy 10 times faster

NSLS-II's Full Field X-ray Imaging beamline can image samples in 3D faster than ever before.

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Swarmlike collective behavior in bicycling

Nature is full of examples of large-scale collective behavior; humans also exhibit this behavior, most notably in pelotons, the mass of riders in bicycle races. Using aerial video footage of bicycle races, researchers analyzed peloton motion to determine what causes changes in the group's large-scale collective behavior and found that riders move through the peloton in a manner similar to circulat

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Explaining a fastball's unexpected twist

An unexpected twist from fastball can make the difference in winning or losing the World Series. However, 'some explanations regarding the different pitches are flat-out wrong,' said a researcher who considers himself a big fan of the game.

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Women more resilient to extreme physical activity than previously reported

Women that underwent extreme physical training and completed a transantarctic expedition did not show any more negative health effects than would be expected in men, according to a new study. The study is the first to suggest that women are not more susceptible to the negative effects of physical exertion and, that with appropriate training and preparation, can be as resilient as men in undertakin

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Exoplanet stepping stones

New observations of a young gas giant demonstrate the power of a ground-based method for searching for signatures of life.

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Bots actually target and pursue individual influencers

New research co-authored by assistant research professor and associate director of Informatics at the University of Southern California Department of Computer Science, Emilio Ferrara, looks at 'social hacking' over social networks that can increase violent commentary and can affect voting behavior.

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Novel machine learning technique for simulating the every day task of dressing

Putting on clothes is a daily, mundane task that most of us perform with little or no thought. We may never take into consideration the multiple steps and physical motions involved when we're getting dressed in the mornings. But that is precisely what needs to be explored when attempting to capture the motion of dressing and simulating cloth for computer animation.

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Antimicrobial resistance is a growing threat to good health and well-being

Antimicrobial-resistant pathogens are one of the largest threats to global health today. As we get older, our immune systems age, increasing our risk of life threatening infections. Without reliable antibiotics, life expectancy could decline for the first time in modern history. If antibiotics become ineffective, common infections could result in hospitalization or even death. Life-saving interve

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How video games turn players into storytellers | David Cage

Have you ever watched a film or read a novel, wishing that you could change the narrative to save your favorite character? Game designer David Cage allows you do just that in his video games, where players make decisions that shape an ever-changing plot. In a talk and live demo, Cage presents a scene from his new project, letting the audience control a character's decisions. "Interactive storytell

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Electrical cable triggers lightweight, fire-resistant cladding discovery

New research has led the successful development of an organic, non-combustible and lightweight cladding core — a product that was previously thought to be impossible to create.

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Reducing the impact forces of water entry

As professional divers complete what's known as a rip dive, their hands remove water in front of the body, creating a cavity that reduces the initial impact force. The rest of the body is aligned to shoot through the same cavity created by the hands. Using the hands to create cavities in the water's surface is similar to the concept behind the fluid-structure studies that researchers are conductin

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Eyes of Creutzfeldt-Jakob disease patients show evidence of prions

By the time symptoms of sporadic Creutzfeldt-Jakob disease (sCJD) are typically discovered, death is looming and inevitable. In a new study, researchers report finding tell-tale evidence of the condition's infectious agent in the eyes of deceased sCJD patients, making the eye a potential source for both early CJD detection and prevention of disease transmission.

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Hidden giants in forest soils

Only a fraction of the microbes residing in, on and around soils have been identified through efforts to understand their contributions to global nutrient cycles. Soils are also home to countless viruses that can infect microbes, impacting their ability to regulate these global cycles. Giant virus genomes have been discovered for the first time in a forest soil ecosystem.

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Neuroimaging study reveals 'hot spot' for cue-reactivity in substance-dependent population

Medical University of South Carolina neuroscientists have identified a region of brain that may be a new clinical target to treat addiction. In a Translational Psychiatry article, they report locating a 'hot spot' in brain activity associated with substance use disorder that could potentially be targeted by brain stimulation therapies such as transcranial magnetic stimulation (TMS). These findings

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Why macrophages rest in healthy tissue

ETH scientists have shown that the immune system's macrophages are regulated not only biochemically, but mechanically as well. This could explain why the cells are less active in healthy tissue.

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The final stage before a big bang?

The Phlegraean Fields in the west of Naples have entered the first stage of a new caldera cycle. That is the conclusion vulcanologists have reached on the basis of rock analysis and with the help of a model.

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Half the Time, Psychology Results Not Reproducible: Study

These failures were not due to differences among sample populations.

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How and Why Scientists Redefined the Kilogram

Illustrations from the Scientific American archive break down this “massive” development — Read more on ScientificAmerican.com

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Hungry ticks work harder to find you

Biologists at the University of Cincinnati say the hungrier ticks are, the harder they try to find you or other hosts. The findings could have implications for the spread of tick-borne disease such as Lyme or Rocky Mountain Spotted Fever.

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Where you go tells who you are — and vice versa

Mining data to analyze tracking patterns, scientists can infer the population travel demand level in a region from the trajectories of just a portion of travelers. They found three distinct groups whose demographics they could infer based on their travel patterns: seniors, who travel to a wider variety of places in a day; workers, who stay mostly at work or at home; parents, who visit more individ

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4,000-year-old termite mounds found in Brazil are visible from space

Researchers have found that a vast array of regularly spaced, still-inhabited termite mounds in northeastern Brazil–covering an area the size of Great Britain — are up to about 4,000 years old.

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Scientists discover new 'pinwheel' star system

An international team of scientists has discovered a new, massive star system — one that also challenges existing theories of how large stars eventually die.

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Major natural carbon sink may soon become carbon source

Peatlands in some parts of the world, including Canada, Siberia and Southeast Asia, have already turned into significant carbon sources. The same fate may be coming soon for the Peruvian peatlands.

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Current climate models underestimate warming by black carbon aerosol

Researchers have discovered a new, natural law that sheds light on the fundamental relationship between coated black carbon and light absorption.

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Australian mammals at greatest risk from cats and foxes, new study

New research led by the Threatened Species Recovery Hub has revealed which Australian mammals are most vulnerable to cats and foxes, and many much-loved potoroos, bandicoots and bettongs, as well as native rodents, are at the top of the list.

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Meta-surface corrects for chromatic aberrations across all kinds of lenses

SEAS researchers have developed a so-called metacorrector, a single-layer surface of nanostructures that can correct chromatic aberrations across the visible spectrum and can be incorporated into commercial optical systems, from simple lenses to high-end microscopes.

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How reliable are search terms for SEO and SEM results?

With billions of dollars spent each year on search engine optimization (SEO) and search engine marketing (SEM), the power of search terms holds more value than ever. But more than a few digital marketing professionals have become frustrated over the years over the limits just how much can be assumed and predicted based on the search terms themselves.

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Watch: Intensive teaching ‘rewires’ student brains

New research shows how intensive instruction changes brain circuitry in struggling readers. The early years are when the brain develops the most, forming neural connections that pave the way for how a child—and the eventual adult—will express feelings, embark on a task, and learn new skills and concepts. Scientists have even theorized that the anatomical structure of neural connections forms the

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The Animals of California’s Devastating Camp Fire

The Camp Fire, now California’s deadliest and most destructive wildfire ever recorded, is 70 percent contained, after raging for 12 days. The Sacramento Bee reports that the current number of deaths stands at 79, with 699 people still unaccounted for. Wrapped up in the disaster from the beginning, along with the human residents of Paradise and the neighboring area, have been the animal residents—

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The App at the Heart of the Movement to End Affirmative Action

OiYan Poon stumbled upon WeChat largely by accident. Poon is a professor at Colorado State University who studies the racial politics of higher education. For years she had consistently found that most Asian Americans supported affirmative action, but in 2014, something surprised her: A fledgling network of politically savvy Asian Americans had derailed a Democrat-backed ballot initiative in Cali

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Mars moon got its grooves from rolling stones

Computer models shine a light on the origin of the Mars moon Phobos' distinctive grooves.

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Is Antarctica becoming more like Greenland?

Antarctica is high and dry and mostly bitterly cold, and it's easy to think of its ice and snow as locked away in a freezer, protected from melt except around its low-lying coasts and floating ice shelves. But that view may be wrong.

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The shape of things to come: Flexible, foldable supercapacitors for energy storage

Scientists have discovered a way of making paper supercapacitors for electricity storage.

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How to melt gold at room temperature

When the tension rises, unexpected things can happen — not least when it comes to gold atoms. Researchers have now managed, for the first time, to make the surface of a gold object melt at room temperature.

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Dogs know when they don't know

Researchers have shown that dogs possess some 'metacognitive' abilities — specifically, they are aware of when they do not have enough information to solve a problem and will actively seek more information. The researchers created a test in which dogs had to find a reward behind one of two fences. They found that the dogs looked for additional information significantly more often when they had no

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Explaining the plummeting cost of solar power

The dramatic drop in the cost of solar photovoltaic (PV) modules, which has fallen by 99 percent over the last four decades, is often touted as a major success story for renewable energy technology. But one question has never been fully addressed: What exactly accounts for that stunning drop? A new analysis has pinpointed what caused the savings, including the policies and technology changes that

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How female hyaenas came to dominate males

In most animal societies, members of one sex dominate those of the other. Is this, as widely believed, an inevitable consequence of a disparity in strength and ferocity between males and females? Not necessarily. A new study on wild spotted hyaenas shows that in this social carnivore, females dominate males because they can rely on greater social support than males, not because they are stronger o

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Norgen Biotek Achieves Illumina Propel Certification as a Service Provider for Next Generation Sequencing

Norgen Biotek Corp., an innovative privately held Canadian biotechnology company focusing primarily on nucleic acid and protein stabilization and purification, as well as providing high quality services to the scientific community, today announced that it has become Propel-Certified through Illumina as a Next Generation Sequencing (NGS) service provider.

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To predict the future, the brain uses two clocks

One type of anticipatory timing relies on memories from past experiences. The other on rhythm. Both are critical to our ability to navigate and enjoy the world, and UC Berkeley scientists have found they are handled in two different parts of the brain.

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Among birds-of-paradise, good looks are not enough to win a mate

Male birds-of-paradise are justly world famous for their wildly extravagant feather ornaments, complex calls, and shape-shifting dance moves — all evolved to attract a mate. New research published in the open-access journal PLOS Biology suggests for the first time that female preferences drive the evolution of physical and behavioral trait combinations that may also be tied to where the male does

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Gene testing doesn't add much information for antidepressant or antipsychotic prescribing

Pharmacogenetic tests are marketed as an aid to psychiatrists in selecting the antidepressant or antipsychotic medication that will work best in individual patients, based on their genetic makeup. But for most patients, these pharmacogenetic tests don't provide much useful information, beyond a basic understanding of how antidepressant and antipsychotic drugs are metabolized, suggests a study in t

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Clemson researchers reveal secrets of parasite that causes African sleeping sickness

A team of Clemson University researchers wants to protect humans and other mammals from the debilitating and even deadly effects of African sleeping sickness. James Morris, a Clemson professor in the College of Science's department of genetics and biochemistry, said that studying the cause of the disease is vital because, although the transmission of African sleeping sickness by tsetse flies has b

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4 Infant Botulism Cases Linked to Honey-Dipped Pacifiers

The FDA warns caregivers not to give honey to infants younger than 12-months

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Inside AlienCon, the Annual Gathering of 'Ancient Aliens' Fans

One of basic cable's longest-running and most popular shows has attracted a loyal following—and spawned a convention.

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The curious case of the electric carving knife

Technology This Thanksgiving, consider plugging in your knife. Electric knives seem cheesy. And to be honest, they basically are. But with the right one, you can cut meat into pretty slices.

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Fish can detox too — but not so well, when it comes to mercury

By examining the tissues at a subcellular level, the researchers discovered yelloweye rockfish were able to immobilize several potentially toxic elements within their liver tissues (cadmium, lead, and arsenic) thus preventing them from interacting with sensitive parts of the cell. But mercury was found in concentrations known to be toxic – and most of it was in sensitive sites, such as mitochondri

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Machine learning can be used to predict which patients require emergency admission

Machine learning can be used to analyse electronic health records and predict the risk of emergency hospital admissions, a new study from The George Institute for Global Health at the University of Oxford has found.

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Parental 'feeding styles' reflect children's genes

New research from King's College London and UCL challenges the idea that a child's weight largely reflects the way their parents feed them. Instead, parents appear to adopt feeding styles in response to their children's natural body weight, which is largely genetically influenced.

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Babies born with broken hearts

Researchers are exploring how irregular filling mechanics may contribute to defects in developing fetal hearts because inefficient filling leads to energy losses that alter the heart's structure and performance, and studying how filling mechanics and flow structure change over the course of gestation. During the APS Division of Fluid Dynamics 71st Annual Meeting, Nov. 18-20, they will discuss the

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Among birds-of-paradise, good looks are not enough to win a mate

Male birds-of-paradise are notorious for their wildly extravagant feather ornaments, complex calls, and shape-shifting dance moves — all evolved to attract a mate. New research published in the open-access journal PLOS Biology on Nov. 20 suggests for the first time that female preferences drive the evolution of combinations of physical and behavioral traits that may also be tied to where the male

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Transparency and reproducibility of biomedical research is improving

New research publishing Nov. 20 in the open-access journal PLOS Biology from Joshua Wallach, Kevin Boyack, and John Ioannidis suggests that progress has been made in key areas of research transparency and reproducibility. The authors randomly sampled biomedical journal articles published between 2015 and 2017 and assessed measures of reproducibility and transparency.

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The Trojan horse of Staphylococcus aureus

A weapons of Staphylococcus aureus is ?-toxin, which destroys host cells by forming pores in their membranes. Researchers at UNIGE have identified the mechanism that allows these pores to be harmful. They uncover how proteins of human cells assemble into a complex to which pores are docked. They also demonstrate that blocking the assembly of the complex by removing one of its elements allows pores

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The taming of the dog, cow, horse, pig and rabbit

Research into one of the 'genetic orchestra conductors', microRNAs, sheds light on our selectively guided evolution of domestic pets and farmyard animals such as dogs and cows.

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Model of quantum artificial life on quantum computer

Researchers have developed a quantum biomimetic protocol that reproduces the characteristic process of Darwinian evolution adapted to the language of quantum algorithms and quantum computing. The researchers anticipate a future in which machine learning, artificial intelligence and artificial life itself will be combined on a quantum scale.

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Smart car technologies save drivers $6.2 billion on fuel costs each year

In the first study to assess the energy impact of smart technology in cars, researchers have put a number on the potential fuel-cost savings alone: $6.2 billion.

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Could yesterday's Earth contain clues for making tomorrow's medicines?

Researchers described initial steps toward achieving chemistries that encode information in a variety of conditions that might mimic the environment of prehistoric Earth.

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Mmore effective hydrogel for healing wounds

Researchers have created an easy-to-make, low-cost injectable hydrogel that could help wounds heal faster, especially for patients with compromised health issues.

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Who Would Spend $17 on Toothpaste?

I wasn’t at an Aesop boutique in Brooklyn to visit the $17 toothpaste—I was there to visit the $39 hand soap. I say “visit,” because the other ways to describe going into a store to look at a product all imply that some sort of purchase might be in my future. I just wanted to stand in a beautiful boutique for a second and see something ridiculous while I waited for a ride home from getting my gla

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For Trump, the Truth About Jamal Khashoggi Is Beside the Point

In the battle between Donald Trump’s gut and contradictory evidence, it’s a safe bet which will win the president’s favor. Days after major newspapers reported on a CIA assessment claiming that Saudi Crown Prince Mohammed bin Salman ordered the killing of the journalist Jamal Khashoggi, the president declared his fulsome support for Saudi Arabia. “Our intelligence agencies continue to assess all

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Among birds-of-paradise, good looks are not enough to win a mate

Male birds-of-paradise are notorious for their wildly extravagant feather ornaments, complex calls, and shape-shifting dance moves—all evolved to attract a mate. New research published in the open-access journal PLOS Biology on November 20 suggests for the first time that female preferences drive the evolution of combinations of physical and behavioral traits that may also be tied to where the mal

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Transparency and reproducibility of biomedical research is improving

Over the past few years, there have been numerous efforts to promote open science practices across the scientific literature. With increased support for sharing of both data and study protocols, an increased appreciation of the importance of reproducing prior research results, and a growing number of journals requiring reporting guidelines and disclosure statements, is there a noticeable impact of

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Don’t spank your kids. Do time-outs and positive talk instead, pediatricians say

A pediatrician group recommends against spanking children — ever — and points instead to positive reinforcement and time-outs to cool off.

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6 Strange Facts about the Interstellar Visitor 'Oumuamua

— Read more on ScientificAmerican.com

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Aquatic animals that jump out of water inspire leaping robots

Ever watch aquatic animals jump out of the water and wonder how they manage to do it in such a streamlined and graceful way? Researchers who specialize in water entry and exit in nature had the same question.

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A Mexican cavefish with a scarred heart

Scientists are studying a guppy-sized, blind, translucent fish that lives in the cave systems of northern Mexico to figure out why some animals can regenerate their hearts, while others just scar.

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Scientists develop 'contact lens' patch to treat eye diseases

Scientists have developed a 'contact lens' patch with microneedles that could be a painless and efficient alternative to current methods of treating eye diseases such as glaucoma. Patients are unable to keep up with the prescribed regime of current localized treatment methods like eye drops, which are hindered by the eye's natural defenses, blinking and tears. Eye injections can be painful and car

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Frogs breed young to beat virus

Frogs from groups exposed to a deadly virus are breeding at younger ages, new research suggests.

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When storing memories, brain prioritizes those experiences that are most rewarding

A new study finds that overnight the brain automatically preserves memories for important events and filters out the rest, revealing new insights into the processes that guide decision making and behavior.

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How your moving brain sees the world

What we see is not only determined by what is really there, but also depends on whether we are paying attention, whether we are moving, excited or interested. In a new study, scientists uncover that the processing of visual information in the brain is indeed modulated by our own behavior.

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Hyena population recovered slowly from a disease epidemic

Infectious diseases can substantially reduce the size of wildlife populations, thereby affecting both the dynamics of ecosystems and biodiversity. Predicting the long-term consequences of epidemics is thus essential for conservation. Researchers have now developed a mathematical model to determine the impact of a major epidemic of canine distemper virus (CDV) on the population of spotted hyenas in

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A Trojan horse delivery method for miRNA-enriched extracellular vesicles

A method for large-scale production of extracellular vesicles enriched with specific microRNAs (miRNAs) has been developed in the Wake Forest Institute for Regenerative Medicine (WFIRM) labs, offering a manufacturing standardization process which may have therapeutic applications and clinical impact.

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Searching for Antarctica’s penguins, lost meteorites, and oldest ice

As winter approaches in the northern hemisphere, hundreds of scientists are heading to Antarctica to study the solar system’s past and predict Earth’s future

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A Foiled Climate Fund Request Would Have Aided Oil Industry

A request from Bahrain to alleviate its water crisis would also have offset cleanup costs for oil companies — Read more on ScientificAmerican.com

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SNL’s New Rap Parodies Tell the Same Old Joke

Ruth Bader Ginsburg has been a fake hip-hop icon since at least 2013, when the nickname Notorious RBG went viral, thereby finally informing the venerated justice of the existence of Biggie Smalls . But she didn’t get her big-budget debut single until this past weekend . “Supreme Court’s a boys’ club, she holds it down, no cares given,” rapped a shirtless, chain-wearing Chris Redd on SNL while Kat

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Ivanka Trump Isn’t Fooling Anyone

The jokes write themselves, though if you search Twitter for “ but her emails ,” it turns out hundreds of people write the jokes as well. As The Washington Post reported Monday evening, Ivanka Trump, the president’s oldest daughter and a senior White House adviser, sent hundreds of emails pertaining to government business using a personal email account in 2017, in violation of federal records law

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Strong but uneven spending in medical and health R&D across sectors over five-year period

Total US investment in medical and health research and development (R&D) in the US grew by 27 percent over the five-year period from 2013 to 2017, led by industry and the federal government, according to US Investments in Medical and Health Research and Development, a new report from Research!America. Industry accounted for 67 percent of total spending in 2017, followed by the federal government a

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Cutting the legs off cancer

Melanoma skin cancer tumors grow larger and are more likely to metastasize due to interactions between a pair of molecules, according to experiments in mice and human cells. The results may restore the potential for a type of cancer therapy previously abandoned in clinical trials. The results also implicate one molecule already connected to obesity and dementia as a potential cause of metastasis,

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Creutzfeldt-Jakob disease spreads prions throughout the eyes, researchers find

Researchers recently studied the eyes of 11 people with sporadic Creutzfeldt-Jakob disease (sCJD), the most common and well-known prion disorder. This week in mBio, they report finding prion seeds — the infectious proteins that cause the disease — spread throughout the eyes of all the patients.

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Studying water flow for more efficient aquaponic systems

In aquaponics, the hydroponic crops use the nutrients from fish waste as fertilizer while the fish benefit from the plants' nutrient uptake capability to improve water quality. The treated water is then recirculated to the plant grow beds and fish culture tanks via a pipe system. Researchers who are studying ways to improve water flow for more efficient aquaponic systems will present their work at

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Why Henry David Thoreau was drawn to yoga

The famed author was heavily influenced by Indian literature, informing his decision to self-exile on Walden Pond. He was introduced to these texts by his good friend's father, William Emerson. Yoga philosophy was in America a century before any physical practices were introduced. None Though yoga today is associated with expensive leggings and an infestation of Instagram selfies, the philosophic

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10 exercises under 10 minutes that make a health difference

A recent study from the Department of Health and Human Services found that 80 percent of Americans don't exercise enough. Small breaks from work add up, causing experts to recommend short doses of movement rather than waiting to do longer workouts. Rethinking what exercise is can help you frame how you move throughout your day. None Yesterday I published this article detailing the fact that 80 pe

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Studying water flow for more efficient aquaponic systems

An aquaponic system is an example of an integrated farming method in which the waste byproduct from one production process, like raising fish and other seafood, serves as a nutrient for another part of the system—like growing plants, for instance.

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Healthcare providers — not hackers — leak more of your data

New research found that more than half of the recent personal health information, or PHI, data breaches were because of internal issues with medical providers — not because of hackers or external parties.

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Get dressed!

Computer scientists from the Georgia Institute of Technology and Google Brain, Google's artificial intelligence research arm, have devised a novel computational method, driven by machine learning techniques, to successfully and realistically simulate the multi-step process of putting on clothes. The new method will be presented at SIGGRAPH Asia 2018

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A toxic bullet involved in bacterial competition found by researchers

A bacterial toxin that allows an infectious strain of bacteria to defeat its competitors has been discovered by Imperial College London scientists.

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Is “choline and geranate” an ionic liquid or deep eutectic solvent system? [Biological Sciences]

The definition of CAGE (choline and geranate) presented by Banerjee et al. (1) in PNAS as both an ionic liquid (IL) and deep eutectic solvent (DES) is contradictory, goes against their previous classification of CAGE, and prevents the work from being discussed or understood in context with the appropriate literature….

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Reply to Rogers and Gurau: Definitions of ionic liquids and deep eutectic solvents [Biological Sciences]

Regarding classification of materials as ionic liquids (ILs) and deep eutectic solvents (DESs), Rogers and coworkers elegantly stated in their previous article (1) that the current definitions are based on extreme behaviors and the reality is somewhere in the middle. By definition, the behavior of ILs is dominated by ionic…

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Tagging the musical beat: Neural entrainment or event-related potentials? [Biological Sciences]

In a recent issue of PNAS, Lenc et al. (1) report that steady-state responses (SSRs) induced by rhythmic auditory stimuli are enhanced when listeners attend to low-frequency sounds, particularly when these sounds reflect salient periodicities like the beat or the meter. Lenc et al. (1) interpret this finding as an…

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Reply to Novembre and Iannetti: Conceptual and methodological issues [Biological Sciences]

In a recent study in PNAS on musical rhythm (1), we show that EEG responses at beat- and meter-related frequencies are selectively enhanced when conveyed by low-frequency sounds, especially in complex syncopated rhythms with no prominent acoustic energy at beat- and meter-related frequencies in the stimulus. In their letter, Novembre…

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Ocean circulation, ice shelf, and sea ice interactions explain Dansgaard-Oeschger cycles [Earth, Atmospheric, and Planetary Sciences]

The last glacial interval experienced abrupt climatic changes called Dansgaard–Oeschger (DO) events. These events manifest themselves as rapid increases followed by slow decreases of oxygen isotope ratios in Greenland ice core records. Despite promising advances, a comprehensive theory of the DO cycles, with their repeated ups and downs of isotope…

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A flexible organic reflectance oximeter array [Engineering]

Transmission-mode pulse oximetry, the optical method for determining oxygen saturation in blood, is limited to only tissues that can be transilluminated, such as the earlobes and the fingers. The existing sensor configuration provides only single-point measurements, lacking 2D oxygenation mapping capability. Here, we demonstrate a flexible and printed sensor array…

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Engineering the protein secretory pathway of Saccharomyces cerevisiae enables improved protein production [Applied Biological Sciences]

Baker’s yeast Saccharomyces cerevisiae is one of the most important and widely used cell factories for recombinant protein production. Many strategies have been applied to engineer this yeast for improving its protein production capacity, but productivity is still relatively low, and with increasing market demand, it is important to identify…

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Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERB{alpha} complex [Biochemistry]

The nuclear receptor REV-ERBα integrates the circadian clock with hepatic glucose and lipid metabolism by nucleating transcriptional comodulators at genomic regulatory regions. An interactomic approach identified O-GlcNAc transferase (OGT) as a REV-ERBα−interacting protein. By shielding cytoplasmic OGT from proteasomal degradation and favoring OGT activity in the nucleus, REV-ERBα cyclically incre

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Coupled molecular dynamics mediate long- and short-range epistasis between mutations that affect stability and aggregation kinetics [Biophysics and Computational Biology]

Multiple mutations are typically required to significantly improve protein stability or aggregation kinetics. However, when several substitutions are made in a single protein, the mutations can potentially interact in a nonadditive manner, resulting in epistatic effects, which can hamper protein-engineering strategies to improve thermostability or aggregation kinetics. Here, we have…

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Evolution of weak cooperative interactions for biological specificity [Cell Biology]

A hallmark of biological systems is that particular functions and outcomes are realized in specific contexts, such as when particular signals are received. One mechanism for mediating specificity is described by Fisher’s “lock and key” metaphor, exemplified by enzymes that bind selectively to a particular substrate via specific finely tuned…

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Polypyrimidine tract-binding protein blocks miRNA-124 biogenesis to enforce its neuronal-specific expression in the mouse [Developmental Biology]

MicroRNA (miRNA)-124 is expressed in neurons, where it represses genes inhibitory for neuronal differentiation, including the RNA binding protein PTBP1. PTBP1 maintains nonneuronal splicing patterns of mRNAs that switch to neuronal isoforms upon neuronal differentiation. We find that primary (pri)-miR-124-1 is expressed in mouse embryonic stem cells where mature miR-124…

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Silencing of retrotransposon-derived imprinted gene RTL1 is the main cause for postimplantational failures in mammalian cloning [Developmental Biology]

Substantial rates of fetal loss plague all in vitro procedures involving embryo manipulations, including human-assisted reproduction, and are especially problematic for mammalian cloning where over 90% of reconstructed nuclear transfer embryos are typically lost during pregnancy. However, the epigenetic mechanism of these pregnancy failures has not been well described. Here…

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Behavior-dependent cis regulation reveals genes and pathways associated with bower building in cichlid fishes [Evolution]

Many behaviors are associated with heritable genetic variation [Kendler and Greenspan (2006) Am J Psychiatry 163:1683–1694]. Genetic mapping has revealed genomic regions or, in a few cases, specific genes explaining part of this variation [Bendesky and Bargmann (2011) Nat Rev Gen 12:809–820]. However, the genetic basis of behavioral evolution remains…

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Human-like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats [Genetics]

Prostate cancer is a leading cause of cancer death in men over 50 years of age, and there is a characteristic marked decrease in Zn content in the malignant prostate cells. The cause and consequences of this loss have thus far been unknown. We found that in middle-aged rats a…

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Criticality in tumor evolution and clinical outcome [Genetics]

How mutation and selection determine the fitness landscape of tumors and hence clinical outcome is an open fundamental question in cancer biology, crucial for the assessment of therapeutic strategies and resistance to treatment. Here we explore the mutation-selection phase diagram of 6,721 tumors representing 23 cancer types by quantifying the…

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Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory [Immunology and Inflammation]

Staphylococcus aureus is the leading cause of skin and skin structure infection (SSSI), a primary portal of entry for invasive infection. Our prior studies discovered a role for protective innate memory against recurrent methicillin-resistant S. aureus (MRSA) SSSI. In the present study, the dynamics and mechanisms of this response were…

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Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration [Medical Sciences]

Recessive Stargardt disease (STGD1) is an inherited blinding disorder caused by mutations in the Abca4 gene. ABCA4 is a flippase in photoreceptor outer segments (OS) that translocates retinaldehyde conjugated to phosphatidylethanolamine across OS disc membranes. Loss of ABCA4 in Abca4−/− mice and STGD1 patients causes buildup of lipofuscin in the…

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Oncogenic role of SFRP2 in p53-mutant osteosarcoma development via autocrine and paracrine mechanism [Medical Sciences]

Osteosarcoma (OS), the most common primary bone tumor, is highly metastatic with high chemotherapeutic resistance and poor survival rates. Using induced pluripotent stem cells (iPSCs) generated from Li–Fraumeni syndrome (LFS) patients, we investigate an oncogenic role of secreted frizzled-related protein 2 (SFRP2) in p53 mutation-associated OS development. Interestingly, we find…

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Vorinostat, a pan-HDAC inhibitor, abrogates productive HPV-18 DNA amplification [Medical Sciences]

Human papillomaviruses (HPVs) cause epithelial proliferative diseases. Persistent infection of the mucosal epithelia by the high-risk genotypes can progress to high-grade dysplasia and cancers. Viral transcription and protein activities are intimately linked to regulation by histone acetyltransferases and histone deacetylases (HDACs) that remodel chromatin and regulate gene expression. HDACs are..

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Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model [Neuroscience]

Alzheimer’s disease (AD) is the leading cause of age-related dementia. Neuropathological hallmarks of AD include brain deposition of β-amyloid (Aβ) plaques and accumulation of both hyperphosphorylated and acetylated tau. RGFP-966, a brain-penetrant and selective HDAC3 inhibitor, or HDAC3 silencing, increases BDNF expression, increases histone H3 and H4 acetylation, decreases tau…

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Face cells in orbitofrontal cortex represent social categories [Neuroscience]

Perceiving social and emotional information from faces is a critical primate skill. For this purpose, primates evolved dedicated cortical architecture, especially in occipitotemporal areas, utilizing face-selective cells. Less understood face-selective neurons are present in the orbitofrontal cortex (OFC) and are our object of study. We examined 179 face-selective cells in…

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Autocrine signaling by an Aplysia neurotrophin forms a presynaptic positive feedback loop [Neuroscience]

Whereas short-term plasticity is often initiated on one side of the synapse, long-term plasticity involves coordinated changes on both sides, implying extracellular signaling. We have investigated the possible signaling role of an Aplysia neurotrophin (ApNT) in facilitation induced by serotonin (5HT) at sensory-to-motor neuron synapses in culture. ApNT is an…

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Arabidopsis thaliana NGATHA1 transcription factor induces ABA biosynthesis by activating NCED3 gene during dehydration stress [Plant Biology]

The plant hormone abscisic acid (ABA) is accumulated after drought stress and plays critical roles in the responses to drought stress in plants, such as gene regulation, stomatal closure, seed maturation, and dormancy. Although previous reports revealed detailed molecular roles of ABA in stress responses, the factors that contribute to…

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Flavonols control pollen tube growth and integrity by regulating ROS homeostasis during high-temperature stress [Plant Biology]

Plant reproduction requires long-distance growth of a pollen tube to fertilize the female gametophyte. Prior reports suggested that mutations altering synthesis of flavonoids, plant specialized metabolites that include flavonols and anthocyanins, impair pollen development in several species, but the mechanism by which flavonols enhanced fertility was not defined. Here, we…

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Quantifying resilience of humans and other animals [Medical Sciences]

All life requires the capacity to recover from challenges that are as inevitable as they are unpredictable. Understanding this resilience is essential for managing the health of humans and their livestock. It has long been difficult to quantify resilience directly, forcing practitioners to rely on indirect static indicators of health….

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An abundance of developmental anomalies and abnormalities in Pleistocene people [Anthropology]

Diverse developmental abnormalities and anomalous features are evident in the Pleistocene Homo fossil record, varying from minor but rare dental, vertebral, and carpal variants to exceptional systemic disorders. There are currently 75 documented anomalies or abnormalities from 66 individuals, spanning the Pleistocene but primarily from the Late Pleistocene Middle and…

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Bulk electronic transport impacts on electron transfer at conducting polymer electrode-electrolyte interfaces [Applied Physical Sciences]

Electrochemistry is an old but still flourishing field of research due to the importance of the efficiency and kinetics of electrochemical reactions in industrial processes and (bio-)electrochemical devices. The heterogeneous electron transfer from an electrode to a reactant in the solution has been well studied for metal, semiconductor, metal oxide,…

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Acoustic phonon lifetimes limit thermal transport in methylammonium lead iodide [Applied Physical Sciences]

Hybrid organic–inorganic perovskites (HOIPs) have become an important class of semiconductors for solar cells and other optoelectronic applications. Electron–phonon coupling plays a critical role in all optoelectronic devices, and although the lattice dynamics and phonon frequencies of HOIPs have been well studied, little attention has been given to phonon lifetimes….

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Deciphering the structure of the condensin protein complex [Biochemistry]

Protein assemblies consisting of structural maintenance of chromosomes (SMC) and kleisin subunits are essential for the process of chromosome segregation across all domains of life. Prokaryotic condensin belonging to this class of protein complexes is composed of a homodimer of SMC that associates with a kleisin protein subunit called ScpA….

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Optimal molecular crowding accelerates group II intron folding and maximizes catalysis [Biochemistry]

Unlike in vivo conditions, group II intron ribozymes are known to require high magnesium(II) concentrations ([Mg2+]) and high temperatures (42 °C) for folding and catalysis in vitro. A possible explanation for this difference is the highly crowded cellular environment, which can be mimicked in vitro by macromolecular crowding agents. Here,…

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Crystal structure of heme A synthase from Bacillus subtilis [Biochemistry]

Heme A is an essential cofactor for respiratory terminal oxidases and vital for respiration in aerobic organisms. The final step of heme A biosynthesis is formylation of the C-8 methyl group of heme molecule by heme A synthase (HAS). HAS is a heme-containing integral membrane protein, and its structure and…

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Crystal structure of human mARC1 reveals its exceptional position among eukaryotic molybdenum enzymes [Biochemistry]

Biotransformation enzymes ensure a viable homeostasis by regulating reversible cycles of oxidative and reductive reactions. The metabolism of nitrogen-containing compounds is of high pharmaceutical and toxicological relevance because N-oxygenated metabolites derived from reactions mediated by cytochrome P450 enzymes or flavin-dependent monooxygenases are in some cases highly toxic or mutagenic. Th

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Arginine-rich cell-penetrating peptides induce membrane multilamellarity and subsequently enter via formation of a fusion pore [Biophysics and Computational Biology]

Arginine-rich cell-penetrating peptides do not enter cells by directly passing through a lipid membrane; they instead passively enter vesicles and live cells by inducing membrane multilamellarity and fusion. The molecular picture of this penetration mode, which differs qualitatively from the previously proposed direct mechanism, is provided by molecular dynamics simulations….

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Highly disordered histone H1-DNA model complexes and their condensates [Biophysics and Computational Biology]

Disordered proteins play an essential role in a wide variety of biological processes, and are often posttranslationally modified. One such protein is histone H1; its highly disordered C-terminal tail (CH1) condenses internucleosomal linker DNA in chromatin in a way that is still poorly understood. Moreover, CH1 is phosphorylated in a…

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Allosteric landscapes of eukaryotic cytoplasmic Hsp70s are shaped by evolutionary tuning of key interfaces [Biophysics and Computational Biology]

The 70-kDa heat shock proteins (Hsp70s) are molecular chaperones that perform a wide range of critical cellular functions. They assist in the folding of newly synthesized proteins, facilitate assembly of specific protein complexes, shepherd proteins across membranes, and prevent protein misfolding and aggregation. Hsp70s perform these functions by a conserved…

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Self-cleavage of the glmS ribozyme core is controlled by a fragile folding element [Biophysics and Computational Biology]

Riboswitches modulate gene expression in response to small-molecule ligands. Switching is generally thought to occur via the stabilization of a specific RNA structure conferred by binding the cognate ligand. However, it is unclear whether any such stabilization occurs for riboswitches whose ligands also play functional roles, such as the glmS…

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Intrinsic anion diffusivity in lead halide perovskites is facilitated by a soft lattice [Chemistry]

Facile ionic transport in lead halide perovskites plays a critical role in device performance. Understanding the microscopic origins of high ionic conductivities has been complicated by indirect measurements and sample microstructural heterogeneities. Here, we report the direct visualization of halide anion interdiffusion in CsPbCl3–CsPbBr3 single crystalline perovskite nanowire heterojunctions us

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Climate change causes upslope shifts and mountaintop extirpations in a tropical bird community [Ecology]

Montane species worldwide are shifting upslope in response to recent temperature increases. These upslope shifts are predicted to lead to mountaintop extinctions of species that live only near mountain summits, but empirical examples of populations that have disappeared are sparse. We show that recent warming constitutes an “escalator to extinction”…

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Habitat choice meets thermal specialization: Competition with specialists may drive suboptimal habitat preferences in generalists [Ecology]

Limited dispersal is classically considered as a prerequisite for ecological specialization to evolve, such that generalists are expected to show greater dispersal propensity compared with specialists. However, when individuals choose habitats that maximize their performance instead of dispersing randomly, theory predicts dispersal with habitat choice to evolve in specialists, while…

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Decomposition responses to climate depend on microbial community composition [Ecology]

Bacteria and fungi drive decomposition, a fundamental process in the carbon cycle, yet the importance of microbial community composition for decomposition remains elusive. Here, we used an 18-month reciprocal transplant experiment along a climate gradient in Southern California to disentangle the effects of the microbial community versus the environment on…

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Evolution of bidirectional costly mutualism from byproduct consumption [Evolution]

Mutualisms are essential for life, yet it is unclear how they arise. A two-stage process has been proposed for the evolution of mutualisms that involve exchanges of two costly resources. First, costly provisioning by one species may be selected for if that species gains a benefit from costless byproducts generated…

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Unique pelvic fin in a tetrapod-like fossil fish, and the evolution of limb patterning [Evolution]

All living tetrapods have a one-to-two branching pattern in the embryonic proximal limb skeleton, with a single element at the base of the limb (the humerus or femur) that articulates distally with two parallel radials (the ulna and radius or the tibia and fibula). This pattern is also seen in…

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Inclusive fitness consequences of dispersal decisions in a cooperatively breeding bird, the long-tailed tit (Aegithalos caudatus) [Evolution]

Natal dispersal is a demographic trait with profound evolutionary, ecological, and behavioral consequences. However, our understanding of the adaptive value of dispersal patterns is severely hampered by the difficulty of measuring the relative fitness consequences of alternative dispersal strategies in natural populations. This is especially true in social species, in…

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The geographic mosaic of coevolution in mutualistic networks [Evolution]

Ecological interactions shape adaptations through coevolution not only between pairs of species but also through entire multispecies assemblages. Local coevolution can then be further altered through spatial processes that have been formally partitioned in the geographic mosaic theory of coevolution. A major current challenge is to understand the spatial patterns…

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Site-selective chemoenzymatic glycoengineering of Fab and Fc glycans of a therapeutic antibody [Immunology and Inflammation]

The N-glycans attached to the Fab and Fc domains play distinct roles in modulating the functions of antibodies. However, posttranslational site-selective modifications of glycans in antibodies and other multiply glycosylated proteins remain a challenging task. Here, we report a chemoenzymatic method that permits independent manipulation of the Fab and Fc…

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Agonists of growth hormone-releasing hormone (GHRH) inhibit human experimental cancers in vivo by down-regulating receptors for GHRH [Medical Sciences]

The effects of the growth hormone-releasing hormone (GHRH) agonist MR409 on various human cancer cells were investigated. In H446 small cell lung cancer (SCLC) and HCC827 and H460 (non-SCLC) cells, MR409 promoted cell viability, reduced cell apoptosis, and induced the production of cellular cAMP in vitro. Western blot analyses showed…

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NOXA genetic amplification or pharmacologic induction primes lymphoma cells to BCL2 inhibitor-induced cell death [Medical Sciences]

Although diffuse large B cell lymphoma (DLBCL) cells widely express the BCL2 protein, they rarely respond to treatment with BCL2-selective inhibitors. Here we show that DLBCL cells harboring PMAIP1/NOXA gene amplification were highly sensitive to BCL2 small-molecule inhibitors. In these cells, BCL2 inhibition induced cell death by activating caspase 9,…

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Evolution of drug resistance in an antifungal-naive chronic Candida lusitaniae infection [Microbiology]

Management of the limited number of antimicrobials currently available requires the identification of infections that contain drug-resistant isolates and the discovery of factors that promote the evolution of drug resistance. Here, we report a single fungal infection in which we have identified numerous subpopulations that differ in their alleles of…

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Awareness of what is learned as a characteristic of hippocampus-dependent memory [Neuroscience]

We explored the relationship between memory performance and conscious knowledge (or awareness) of what has been learned in memory-impaired patients with hippocampal lesions or larger medial temporal lesions. Participants viewed familiar scenes or familiar scenes where a change had been introduced. Patients identified many fewer of the changes than controls….

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Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists [Pharmacology]

Drugs that treat chronic obstructive pulmonary disease by antagonizing the M3 muscarinic acetylcholine receptor (M3R) have had a significant effect on health, but can suffer from their lack of selectivity against the M2R subtype, which modulates heart rate. Beginning with the crystal structures of M2R and M3R, we exploited a…

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Engineering selectivity into RGK GTPase inhibition of voltage-dependent calcium channels [Physiology]

Genetically encoded inhibitors for voltage-dependent Ca2+ (CaV) channels (GECCIs) are useful research tools and potential therapeutics. Rad/Rem/Rem2/Gem (RGK) proteins are Ras-like G proteins that potently inhibit high voltage-activated (HVA) Ca2+ (CaV1/CaV2 family) channels, but their nonselectivity limits their potential applications. We hypothesized that nonselectivity of RGK inhibition derives

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C4 photosynthesis and climate through the lens of optimality [Plant Biology]

CO2, temperature, water availability, and light intensity were all potential selective pressures that determined the competitive advantage and expansion of the C4 photosynthetic carbon-concentrating mechanism over the last ∼30 My. To tease apart how selective pressures varied along the ecological trajectory of C4 expansion and dominance, we coupled hydraulics to…

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Functional connectivity in central executive network protects youth against cardiometabolic risks linked with neighborhood violence [Psychological and Cognitive Sciences]

Although violent crime has declined in recent decades, it remains a recurring feature of daily life in some neighborhoods. Mounting evidence indicates that such violence has a long reach, which goes beyond family and friends of the victim and undermines the health of people in the surrounding community. However, like…

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Peculiarly pleasant weather for US maize [Sustainability Science]

Continuation of historical trends in crop yield are critical to meeting the demands of a growing and more affluent world population. Climate change may compromise our ability to meet these demands, but estimates vary widely, highlighting the importance of understanding historical interactions between yield and climate trends. The relationship between…

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A multiscale approach to balance trade-offs among dam infrastructure, river restoration, and cost [Sustainability Science]

Aging infrastructure and growing interests in river restoration have led to a substantial rise in dam removals in the United States. However, the decision to remove a dam involves many complex trade-offs. The benefits of dam removal for hazard reduction and ecological restoration are potentially offset by the loss of…

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Sustainable hydropower in the 21st century [Sustainability Science]

Hydropower has been the leading source of renewable energy across the world, accounting for up to 71% of this supply as of 2016. This capacity was built up in North America and Europe between 1920 and 1970 when thousands of dams were built. Big dams stopped being built in developed…

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Correction for Sormaz et al., Default mode network can support the level of detail in experience during active task states [Corrections]

PSYCHOLOGICAL AND COGNITIVE SCIENCES Correction for “Default mode network can support the level of detail in experience during active task states,” by Mladen Sormaz, Charlotte Murphy, Hao-ting Wang, Mark Hymers, Theodoros Karapanagiotidis, Giulia Poerio, Daniel S. Margulies, Elizabeth Jefferies, and Jonathan Smallwood, which was first published August 27, 2018; 10.1073/pnas.1721259115…

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Correction to Supporting Information for Kim et al., Yin-and-yang bifurcation of opioidergic circuits for descending analgesia at the midbrain of the mouse [SI Correction]

NEUROSCIENCE Correction to Supporting Information for “Yin-and-yang bifurcation of opioidergic circuits for descending analgesia at the midbrain of the mouse,” by Jong-Hyun Kim, Gireesh Gangadharan, Junweon Byun, Eui-Ju Choi, C. Justin Lee, and Hee-Sup Shin, which was first published October 8, 2018; 10.1073/pnas.1806082115 (Proc Natl Acad Sci USA 115:11078–11083). The…

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In This Issue [This Week in PNAS]

Role of retinal pigment epithelium in Stargardt macular degeneration Abca4 (red staining indicated by black arrows) in human RPE cells. Recessive Stargardt disease (STGD1) is an inherited blinding disease with no effective treatment. The disease is caused by mutations in the Abca4 gene, which encodes a transporter protein in photoreceptor…

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QnAs with Emilio F. Moran [QnAs]

Globally, hydropower provided 71% of renewable energy in 2016 (1). In the United States, however, large hydropower dams fell out of favor in the 1970s (2). Emilio F. Moran, an environmental social scientist at Michigan State University, has explored the reasons for this shift and future outlook for hydropower. Elected…

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Macrophages and innate immune memory against Staphylococcus skin infections [Immunology and Inflammation]

There is a growing appreciation that macrophages contribute to innate immune memory against microbial pathogens in ways that are distinct from and complementary to adaptive immune memory. In PNAS, Chan et al. (1) report that macrophages develop memory against Staphylococcus aureus skin and skin structure infections (SSSIs) and that this…

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Linker histones as liquid-like glue for chromatin [Biophysics and Computational Biology]

Linker histones play essential roles in chromatin structure and function by binding to nucleosomes and modulating the accessibility of DNA for biological processes such as gene transcription and DNA replication (reviewed in ref. 1). For example, DNA promoters of actively transcribed genes and DNA undergoing replication both exhibit reduced linker…

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Escalator to extinction [Ecology]

Thirty years ago, biologists began to predict how climate change would alter species’ ranges, extinctions, and their roles in ecosystems (1). Since then, evidence has begun to confirm these nascent predictions. The current global temperature rise of ∼1 °C has shifted species up mountains and latitudes (2), altered the timing…

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Evolution of bacterial trade in a two-species community [Evolution]

Our natural world is enriched by mutualisms, where organisms engage in a complex and often colorful trade of goods and services for their mutual benefit (Fig. 1D). An enduring question in evolutionary biology is how does this multispecies complexity emerge from simpler interactions? One-way beneficial relationships, such as those between…

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Inhibition of tumor growth by agonists of growth hormone-releasing hormone [Medical Sciences]

In PNAS, Schally et al. (1) demonstrate the in vivo antitumor activity of the recently developed growth hormone-releasing hormone (GHRH) agonist MR409. Lung cancers were used as the primary tumor model, and the results were extended to colorectal, prostatic, stomach, bladder, breast, and pancreatic cancers (1). GHRH was originally discovered…

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News Feature: Exposing the exposome to elucidate disease [Chemistry]

Environmental factors, not genes constitute most disease risk. Myriad approaches are attempting to use the latest science and technology to more clearly reveal the complex mix of pollutants that contribute. Google Street View cars traversing the roads of Oakland, CA, once captured a picture that goes beyond the usual map….

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Google flytter ind: Ny teknologi skal overvåge både din tøjstil og dine børn

To patentansøgninger fra tech-giganten giver et indblik i Googles visioner for fremtidens smarte hjem.

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Researchers create a more effective hydrogel for healing wounds

Researchers at the University of New Hampshire have created an easy-to-make, low-cost injectable hydrogel that could help wounds heal faster, especially for patients with compromised health issues.

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Graphene foam makes epoxy compound lighter and tougher

Scientists have combined epoxy with a tough graphene foam and carbon nanotube scaffold to build a resilient epoxy composite that’s tougher and as conductive as other compounds but a lot lighter. Epoxy combined with “ultrastiff” graphene foam is substantially tougher than pure epoxy and far more conductive than other epoxy composites while retaining the material’s low density. Researchers say it c

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Can gravitational waves go through extra dimensions? Einstein says no

General relativity has survived its latest test after observations of a violent collision between neutron stars tallied perfectly with Einstein’s theory

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Glamour embraces digital, drops regular print edition

Glamour, the fashion and beauty magazine popular with young women, is ditching its monthly print editions and embracing the online revolution, its chief editor and publishers Conde Nast announced Tuesday.

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$3M reward offered in case where US device was used in IEDs

Federal authorities are offering a $3 million reward for information leading to the arrest and conviction of a man wanted for illegally obtaining U.S. technology that was later used in improvised explosive devices in Iraq.

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EU turns eye to 'fake' Google shopping rivals

The EU's top competition enforcer said Brussels was taking a closer look at allegations that Google had helped introduce false price comparison sites to answer a historic ruling against the search engine giant.

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A Disaster of Our Own Making

There was no horizon in Oakland on Saturday, and the air smells dirty. It’s not like fresh smoke. It’s a staleness. If you stay outside too long you get a little headache. The newest numbers say 71 people have died, more than a thousand missing, and 12,000 buildings burned in the Camp Fire. You’d have to drive well over three hours from here, if the roads were open, to get to anything that’s stil

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UNH researchers create a more effective hydrogel for healing wounds

Researchers at the University of New Hampshire have created an easy-to-make, low-cost injectable hydrogel that could help wounds heal faster, especially for patients with compromised health issues.

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New model predicts which animal viruses may spread among humans

Researchers have developed a model that predicts which of the viruses that can jump from animals to people can also be transmitted from person to person–and are therefore possible sources of human diseases.

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Eyes of CJD patients show evidence of prions

NIH scientists and colleagues have found evidence of the infectious agent of sporadic Creutzfeldt-Jakob disease (CJD) in the eyes of deceased CJD patients. The finding suggests that the eye may be a source for early CJD diagnosis and raises questions about the safety of routine eye exams and corneal transplants. Sporadic CJD, a fatal neurodegenerative prion disease of humans, is untreatable and di

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The shape of things to come: Flexible, foldable supercapacitors for energy storage

A team of researchers from the Plasma Physics Research Centre, Science and Research Branch of Islamic Azad University in Tehran, Iran, have discovered a way of making paper supercapacitors for electricity storage.

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A Metropolis of 200 Million Termite Mounds Was Hidden in Plain Sight

What amount to garbage piles — some are 4,000 years old — are spread over an area the size of Britain in a remote Brazilian forest.

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New model predicts which animal viruses may spread among humans

Researchers have developed a model that predicts which of the viruses that can jump from animals to people can also be transmitted from person to person—and are therefore possible sources of human diseases.

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The shape of things to come: Flexible, foldable supercapacitors for energy storage

A team of researchers from the Plasma Physics Research Centre, Science and Research Branch of Islamic Azad University in Tehran, Iran, have discovered a way of making paper supercapacitors for electricity storage, according to a new study published in the journal Heliyon. At one sheet thick, these new supercapacitors can bend, fold, flex, and still hold electricity.

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Is it possible to ‘replay the tape’ of evolution?

A new review examines how predictable and repeatable evolution is. For the review, researchers examined evidence from a number of empirical studies of evolutionary repeatability and contingency in an effort to fully interrogate ideas about contingency’s role in evolution. The question of evolution’s predictability was notably raised by the late paleontologist Stephen Jay Gould, who advocated the

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NASA's new Mars lander is in for 'seven minutes of terror' on Monday

Space InSight will tell us about the planet's interior, but it's got to stick the landing first. On November 26 a new mission called InSight will attempt to enter the thin Martian atmosphere and land in a region called Elysium Planitia.

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The eyes have it

By the time symptoms of sporadic Creutzfeldt-Jakob disease (sCJD) are typically discovered, death is looming and inevitable. In a new study, researchers at University of California San Diego School of Medicine with colleagues at the National Institutes of Health and UC San Francisco, report finding tell-tale evidence of the condition's infectious agent in the eyes of deceased sCJD patients, making

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Facebook access hit by unspecified problems

Facebook said Tuesday users were having trouble accessing the social network and its other applications such as Instagram, but did not explain the cause of the outages.

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As Facebook faces fire, heat turns up on No. 2 SandbergMark Zuckerberg Facebook

For the past decade, Sheryl Sandberg has been the poised, reliable second-in-command to Facebook CEO Mark Zuckerberg, helping steer Facebook's rapid growth around the world, while also cultivating her brand in ways that hint at aspirations well beyond the social network.

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Mars getting first US visitor in years, a 3-legged geologist

Mars is about to get its first U.S. visitor in years: a three-legged, one-armed geologist to dig deep and listen for quakes.

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Smart car technologies save drivers $6.2 billion on fuel costs each year

On one of the busiest traveling holidays of the year, drivers may be focusing on getting to grandma's house for Thanksgiving dinner, not on what smart car technologies are saving them in fuel costs. But in the first study to assess the energy impact of smart technology in cars, researchers at Stevens Institute of Technology have put a number on the potential fuel-cost savings alone: $6.2 billion.

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Mars moon got its grooves from rolling stones, study suggests

A new study bolsters the idea that strange grooves crisscrossing the surface of the Martian moon Phobos were made by rolling boulders blasted free from an ancient asteroid impact.

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First-of-its-kind study finds loss of local media worsens political polarization

It's no secret that political polarization is creating an ever-widening and divisive gap in American politics. Partisan cable news outlets get the majority of the blame for increasingly isolating people into echo chambers that confirm their own political and ideological ideas, but as these outlets grow in popularity, some local newspapers have begun to silently vanish from the media landscape. Acc

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What Do Shrink-Wrapped Thanksgiving Turkeys and the Higgs Boson Have in Common?

What Do Shrink-Wrapped Thanksgiving Turkeys and the Higgs Boson Have in Common? Both can be made using the power of particle accelerators. ButterballTurkeys_topNteaser.jpg Frozen turkeys and thermal grocery bags filled with food items sit ready for distribution at the Dover Air Force Base, Del. Image credits: U.S. Air Force photo by Roland Balik Culture Tuesday, November 20, 2018 – 11:30 Catherin

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Should Evolution Treat Our Microbes as Part of Us?

Twilight falls on the Tanzanian plain. As the sky turns a deeper purple, a solitary spotted hyena awakens. She trots along the border of her clan’s territory, marking the boundary with a sour paste from under her tail. She sniffs a passing breeze for hints of itinerant males interested in mating, giving little attention to her stomach’s rumbling over the remnants of the previous night’s hunt or t

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What Is Brain Freeze?

What is happening when something as lovely as ice cream causes such awful pain?

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Could yesterday's Earth contain clues for making tomorrow's medicines?

In a paper published recently in the journal Origins of Life and Evolution of Biospheres, UW-Madison researchers described initial steps toward achieving chemistries that encode information in a variety of conditions that might mimic the environment of prehistoric Earth.

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Smart car technologies save drivers $6.2 billion on fuel costs each year

In the first study to assess the energy impact of smart technology in cars, researchers at Stevens Institute of Technology have put a number on the potential fuel-cost savings alone: $6.2 billion.

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Researchers stop 'sneaky' cancer cells in their tracks

A new study by University of Minnesota biomedical engineers shows how they stopped cancer cells from moving and spreading, even when the cells changed their movements.

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Tattoos are popular — half of all Germans regard tattoo inks as safe

Tattoos are popular. Roughly one in eight Germans already has one. A recent representative survey conducted by the German Federal Institute for Risk Assessment (BfR) shows that many people consider tattoos to be safe to health, with almost 90 percent of people who already have a tattoo believing this to be the case. Few of them know that many tattoo inks have not yet been examined.

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Mars moon got its grooves from rolling stones, study suggests

Computer models developed by Brown University researchers shine a light on the origin of the Mars moon Phobos' distinctive grooves.

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A growing list of factors that impact CKD severity for kids

Myriad biological and societal factors can impact the occurrence and accelerate progression of chronic kidney disease for children of African descent – including preterm birth, exposure to toxins during gestation and lower socioeconomic status — and can complicate these children's access to effective treatments.

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First-of-its-kind study finds loss of local media worsens political polarization

Changes to the media environment have increased polarized voting in America through both addition and subtraction. We argue that the decline of local newspapers has contributed to the nationalization of American politics: as local newspapers close, Americans rely more heavily on available national news or partisan heuristics to make political decisions.

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Sugar-sweetened beverages are harmful to health and may be addictive, researchers suggest

Research subjects reported increased headaches, decreased motivation to do work, lack of contentment and ability to concentrate, cravings for sugary drinks, and lower ratings of overall wellbeing.

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A smartphone and new software could help save infants born preterm

Worldwide, preterm birth is a leading cause of death for children under five-years-old. A new algorithm combined with a handheld, smartphone-based device could aid health care workers in remote locations to estimate degrees of prematurity for affected infants. Such information can be critical for administering life-saving treatments.

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Discovery could neutralize West Nile virus

Researchers at Vanderbilt University Medical Center and colleagues have isolated a human monoclonal antibody that can "neutralize" the West Nile virus and potentially prevent a leading cause of viral encephalitis (brain inflammation) in the United States.

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Can genetic therapy help kids with Angelman syndrome overcome seizures?

Angelman syndrome is a genetic disease with no cure. Children grow up with severe intellectual disabilities and a range of other problems, arguably the worst of which are epileptic seizures. Now scientists at the UNC School of Medicine have found evidence that genetic therapy may prevent the enhanced seizure susceptibility.

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Gut protein mutations shield against spikes in glucose

Why is it that, despite consuming the same number of calories, sodium and sugar, some people face little risk of diabetes or obesity while others are at higher risk? A new study by investigators at Brigham and Women's Hospital has uncovered mutations in a gene that appear to help drive this difference.

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Machine learning masters the fingerprint to fool biometric systems

Fingerprint authentication systems are a widely trusted, ubiquitous form of biometric authentication, deployed on billions of smartphones and other devices worldwide. Yet a new study reveals a surprising level of vulnerability in these systems. Using a neural network trained to synthesize human fingerprints, the research team evolved a fake fingerprint that could potentially fool a touch-based aut

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How a crystal is solvated in water

How a molecule from a solid crystal structure is solvated in a liquid solvent has been observed at a molecular level for the first time by chemists at Ruhr-Universität Bochum. The process is too fast to decipher at room temperature. The team from the Ruhr Explores Solvation (Resolv) Cluster of Excellence thus used microscopic methods that work at particularly low temperatures. The team describes t

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Inkjet printers can produce cheap micro-waveguides for optical computers

Scientists from ITMO University have proposed a new technology for creating optical micro-waveguides using inkjet printing. Using this method it is possible to quickly create waveguides with the necessary parameters without expensive equipment and complex procedures. The new technology is optimized for the production of optical elements on an industrial scale. The results are published in Advanced

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Vanderbilt discovery could neutralize West Nile virus

Researchers at Vanderbilt University Medical Center and colleagues have isolated a human monoclonal antibody that can 'neutralize' the West Nile virus and potentially prevent a leading cause of viral encephalitis (brain inflammation) in the United States.

8d

Vaping no boost to quit rates in smokers, study suggests

People who vape and smoke cigarettes are no more likely to drop the nicotine habit than those who just smoke, a new study suggests.

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A smartphone and new software could help save infants born preterm

A new algorithm combined with a handheld, smartphone-based device could aid health care workers in remote locations to estimate degrees of prematurity for affected infants. Such information can be critical for administering life-saving treatments.

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New information on the pathological mechanisms of Alzheimer's disease

Researchers at the University of Helsinki have discovered a mechanism by which harmful tau protein aggregates are transmitted between neurons. Alongside amyloid plaques, tau aggregates in the brain are a significant factor in the progression of Alzheimer's disease.

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Economist calls for creation of global tax authority to tackle inequality

An economist has called for the creation of a global tax authority as a way of tackling worldwide wealth inequality.

8d

The taming of the dog, cow, horse, pig and rabbit

Research at the Earlham Institute into one of the 'genetic orchestra conductors', microRNAs, sheds light on our selectively guided evolution of domestic pets and farmyard animals such as dogs and cows.

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Tropical fish adapt to cold temperatures in coordination with their microbiome

Scientists have discovered that tropical fish can control their gut microbes to better survive extremes of temperature, a study in eLife reveals.

8d

Addams Family Values Is a Darkly Funny Thanksgiving Satire

The ideal Thanksgiving movie has at least two ingredients. The first is a celebration of family, whether actual kin or a makeshift community. The second component is a firm refutation of the holiday’s core mythos. The Thanksgiving story is, after all, quite a bit more complicated than its surface message of harmony between Pilgrims and Native Americans might suggest. That’s why Addams Family Valu

8d

In heart failure, a stronger heart could spell worse symptoms

Patients with stronger-pumping hearts have as many physical and cognitive impairments as those with weaker hearts, suggesting the need for better treatment.

8d

The taming of the dog, cow, horse, pig and rabbit

Research at the Earlham Institute into one of the 'genetic orchestra conductors', microRNAs, sheds light on our selectively guided evolution of domestic pets and farmyard animals such as dogs and cows.

8d

Researchers reveal how a deadly fungal infection shape-shifts into an invasive monster

Monash researchers have shed new light on just how the fungal infection Candida albicans shape-shifts into a deadly version with hyphae or filaments that help it break through human tissues and into the bloodstream. Understanding this process is key to the development of drugs against this fatal infection.

8d

Fish genes hold key to repairing damaged hearts

The Mexican tetra fish can repair its heart after damage — something researchers have been striving to achieve in humans for years. Now, new research funded by the British Heart Foundation (BHF) published in Cell Reports suggests that a gene called lrrc10 may hold the key to this fish's remarkable ability.

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Effects of early education intervention on behavior persist for 4 decades

Adults who had received early life, intensive childhood educational intervention display high levels of fairness in social interactions more than 40 years later, even when being fair comes at a high personal cost, according to a new study by Virginia Tech Carilion Research Institute scientists.

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Being fair: The benefits of early child education

Getting a jump on a low-income child's education can have a positive effect on social behavior even 40 years later, researchers find.

8d

Study: Twitter bots had 'disproportionate' role spreading misinformation in 2016 election

Indiana University computer scientists conducted an analysis of information shared on Twitter during the 2016 U.S. presidential election and found that automated accounts play a disproportionate role in spreading misinformation online.

8d

Study estimates how much time adults sit, how many are physically inactive

Sitting too long and being physically inactive can be bad for your health, and it's important to understand how common these behaviors are among US adults. This study used data from a nationally representative survey of about 5,900 adults to examine sitting time and leisure-time physical activity.

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DNA vaccine reduces both toxic proteins linked to Alzheimer's

A DNA vaccine tested in mice reduces accumulation of both types of toxic proteins associated with Alzheimer's disease, according to research that scientists say may pave the way to a clinical trial.

8d

A Mexican cavefish with a scarred heart

Scientists are studying a guppy-sized, blind, translucent fish that lives in the cave systems of northern Mexico to figure out why some animals can regenerate their hearts, while others just scar. Their research appears Nov. 20 in the journal Cell Reports.

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Low-protein high-carb diet shows promise for healthy brain aging

Low-protein high-carbohydrate diets may be the key to longevity, and healthy brain ageing in particular, according to a new mice study from the University of Sydney.

8d

The Trojan horse of Staphylococcus aureus

A weapons of Staphylococcus aureus is α-toxin, which destroys host cells by forming pores in their membranes. Researchers at UNIGE have identified the mechanism that allows these pores to be harmful. They uncover how proteins of human cells assemble into a complex to which pores are docked. They also demonstrate that blocking the assembly of the complex by removing one of its elements allows pores

8d

SpaceX's Elon Musk renames his big rocket 'Starship'

SpaceX chief executive Elon Musk has announced he is changing the name of his monster rocket BFR, aimed at carrying people to the Moon and possibly one day to Mars, to "Starship."

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Lys og boblebad skal gøre bakterier og enzymer til højtydende kemikaliefabrikker

Konsortium med dansk deltagelse fra Aarhus Universitet og DTU vil øge produktionen af kemikalier med blågrønalger og enzymer, så de kan indgå direkte i industrien.

8d

How Twitter bots get people to spread fake news

Automated bot accounts on Twitter help spread misinformation by strategically encouraging people to make it go viral.

8d

Researchers reveal how a deadly fungal infection shape-shifts into an invasive monster

Monash researchers have shed new light on just how the fungal infection, Candida albicans, shape-shifts into a deadly version with hyphae or filaments that help it break through human tissues and into the bloodstream. Understanding this process is key to the development of drugs against this fatal infection.

8d

A Mexican cavefish with a scarred heart

Scientists are studying a guppy-sized, blind, translucent fish that lives in the cave systems of northern Mexico to figure out why some animals can regenerate their hearts, while others just scar. Their research appears November 20 in the journal Cell Reports.

8d

Twitter bots had 'disproportionate' role spreading misinformation in 2016 election: study

An analysis of information shared on Twitter during the 2016 U.S. presidential election has found that automated accounts—or "bots"—played a disproportionate role in spreading misinformation online.

8d

Hawaii’s Mars Simulations Are Canceled

For the last five years, a small Mars colony thrived in Hawaii, many miles away from civilization. The Hawaii Space Exploration Analog and Simulation, or HI-SEAS , was carried out in a small white dome nestled along the slope of a massive volcano called Mauna Loa. The habitat usually housed six people at a time, for as long as eight months. They prepared freeze-dried meals, took 30-second showers

8d

Letters: Should Fire Protection Be a Privilege?

Kim Kardashian’s Private Firefighters Expose America’s Fault Lines Earlier this month, according to TMZ, a private firefighting crew reportedly helped save Kanye West and Kim Kardashian’s home in Calabasas. The story, Alexis C. Madrigal wrote, “feels uniquely 2018—financial capitalism, inequality, KimYe, the fires of Armageddon.” Reading the recent article on private firefighting certainly made m

8d

Cosmology Is in Crisis Over How to Measure the Universe

A raging debate over the Hubble constant suggests that our standard model of cosmology might be wrong.

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Tropical fish adapt to cold temperatures in coordination with their microbiome

Scientists have discovered that tropical fish can control their gut microbes to better survive extremes of temperature, a study in eLife reveals.

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Impaired cellular force transmission a cause for valvular heart disease

About three per cent of the world's population is affected by valvular heart diseases. It is also the most common cause of heart surgery, as no drug-based treatment is available. Recent research has shed light on the molecular mechanism on valvular disease that is caused by a genetic mutation in Filamin gene. The result of the research will help to further investigate the mechanism by which the me

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Quantum artificial life created on the cloud

The Quantum Technologies for Information Science (QUTIS) research group, led by the Ikerbasque Professor Enrique Solano of the UPV/EHU's Department of Physical Chemistry, has developed a quantum biomimetic protocol that reproduces the characteristic process of Darwinian evolution adapted to the language of quantum algorithms and quantum computing. The researchers anticipate a future in which machi

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Study: Self-management program for patients with COPD boosts quality of life, cuts rehospitalization

Johns Hopkins Medicine researchers report that a program designed to enhance self-care and lead to more seamless management of chronic obstructive pulmonary disease (COPD) in adults successfully reduced rates of emergency room visits and hospitalization, and the burdensome symptoms and limitations caused by the condition.

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New mechanism controlling the master cancer regulator uncovered

Who regulates the key regulator? The Research Center for Molecular Medicine of the Austrian Academy of Sciences reports online in the journal Science about a newly discovered mechanism by which RAS proteins, central to cancer signaling, are regulated in their activity and localization.

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Aspirin Can Help Your Heart. Omega-3s Might. But Together? Maybe Not.

Aspirin and Omega-3 both help the heart — but maybe not together

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Air pollution cuts two years off global average lifespan, says study

Analysis finds toxic air trims lifespans by 1.8 years, making it main threat to human health Air pollution cuts the average lifespan of people around the globe by almost two years, analysis shows , making it the single greatest threat to human health. The research looked at the particulate pollution produced by the burning of fossil fuels by vehicles and industry. It found that in many parts of t

8d

Chemists develop new method for selective binding of proteins

A new method of selectively binding proteins to nanoparticles has been described by a team of German and Chinese researchers headed by Prof. Bart Jan Ravoo, a chemist at the "Center for Soft Nanoscience" at the University of Münster, Germany. The nanoparticles automatically recognize small proteins and enter into highly selective binding with them.

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Revisiting the hub of protein synthesis

A study led by Dr. Ravi Muddashetty at InStem, Bangalore identified distinct markers to distinguish ribosomes that are specialized for producing specific sets of proteins and hinted that this specialization could be important for the development of the nervous system.

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Moms matter, dads don't… when it comes to children's weight

When mothers lose weight, their children slim down too. When mothers are less active, children get fatter. Dad's choices appear to play less of a role.

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Scientists develop potential new treatment for common soft-tissue childhood cancer

CRISPR 'genetic screens' and new approaches to drug design have provided a potential new therapy, which blocks the progression of synovial sarcoma tumors in pre-clinical trials.

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Regulating the immune system's 'regulator'

A research team at the Academy of Immunology and Microbiology, within the Institute for Basic Science (IBS) has discovered a possible therapeutic target that pulls the reins of immunity. On Nature Communications, the scientists reported that mice lacking Foxp1 protein in some specific immune cells are more susceptible to immune-induced inflammation.

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HSPC 'Seeds' reveal VCAM-1+ macrophage role in homing process

To study the detailed architecture of the microenvironment and the regulation mechanism of homing, researchers at the Shanghai Institute of Nutrition and Health of Chinese Academy of Sciences used a zebrafish model to analyze the entire dynamic process of Hematopoietic Stem and Progenitor Cells homing in vivo.

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How your moving brain sees the world

What we see is not only determined by what is really there, but also depends on whether we are paying attention, whether we are moving, excited or interested. In a new study published in Nature Communications, scientists from NERF (Neuro-Electronics Research Flanders) uncover that the processing of visual information in the brain is indeed modulated by our own behavior.

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Personality and mood affect brain response to personal choice

Personality traits and mental health affect how people value personal control in decision making, according to a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

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How a fleet of wind-powered drones is changing our understanding of the ocean | Sebastien de Halleux

Our oceans are unexplored and undersampled — today, we still know more about other planets than our own. How can we get to a better understanding of this vast, important ecosystem? Explorer Sebastien de Halleux shares how a new fleet of wind- and solar-powered drones is collecting data at sea in unprecedented detail, revealing insights into things like global weather and the health of fish stocks

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Focus on ‘ecoregions’ could boost conservation efforts

A new study supports an approach to conservation that focuses on ecoregions—geographically unique regions, such as deserts and rainforests, that contain distinct communities of plants and animals. Scientists have long debated how well ecoregion borders separate species communities. If the borders are strong, protecting an ecoregion, like a rainforest, would effectively protect all of the species

8d

Eel trafficking in the EU, the world's 'biggest wildlife crime'

Billions of euros worth of critically endangered eels are being trafficked each year from Europe, ending up on tables in China and Japan in what campaigners say is "the largest wildlife crime on Earth."

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Danske forskere øger specialdesignede dræbercellers præcision

Forskere ved DTU Nanotech har udviklet screeningsværktøj, der kan skåne raske celler i forbindelse med eksperimentel immunterapi mod kræft.

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Forslag sænker markant grænsen for dioxiner i mad

EU’s fødevareautoritet ønsker en grænseværdi syv gange lavere end i dag. Mange danskere overskrider dermed indtaget i dag, skriver DTU. Men der er en ubekendt spiller på banen.

8d

How too much confidence can benefit entrepreneurs

Researchers have created a computational model to interpret decision-making, learning, and experiences that result in entrepreneurs’ success and failure in market entry and exit. In short, they distilled the traits that lead an entrepreneur to get into, or out of, the startup business. Innovations come and go. Entrepreneurs fail and move on. Researchers have spent decades empirically analyzing th

8d

Mapping dietary data to better understand the relationship between diet and disease

Researchers at Trinity College Dublin have developed a new data mapping method which improves the quality of dietary data collected by short frequency questionnaires (SFQs), thereby improving the capacity to identify diet-disease relationships.

8d

A study suggests that epigenetic treatments could trigger the development of aggressive tumours

A team headed by ICREA researchers Salvador Aznar Benitah and Fran Supek concludes that care should be taken with drugs that inhibit epigenetic factors.Published in Nature Cell Biology, the study is a collaboration between a biomedical lab and a computational lab at IRB Barcelona.

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FEFU physicists have developed concept of new fast non-volatile memory

Using the method of micromagnetic simulation, scientists have found the magnetic parameters and operating modes for the experimental implementation of the fast racetrack memory module running on the spin current. The information carrier in the new type of memory will be the skyrmionium that allows storing more data and read them faster. An article about that is published in "Scientific Reports" jo

8d

Study analyzes the impact of targeted Facebook advertising on U.S. elections

Republican Donald Trump's team spent $44 million on Facebook, running 175,000 different adverts during the 2016 election campaign, compared to a spend of $28 million by Democrat Hillary Clinton.

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Rick's First Gold of the Season | Gold Rush

Still not yet paid, Rick's crew has been waiting seven weeks to see some gold. Stream Full Episodes of Gold Rush: https://www.discovery.com/tv-shows/gold-rush/ Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Join us on Facebook: https://www.facebook.com/GoldRush/ https://www.facebook.com/Discovery Follow us on Twitter: https://twitter.com/Gold_Rush https://twitter.com/Discovery We're on

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New technology paves the way for fewer orange barrels and safer, quicker road repairs

Imagine a drive to grandma's house or to work with fewer "left lane closed ahead" signs, fewer detour signs, fewer orange barrels and also safer travel near road crews. That may soon be possible with new technology from Purdue University researchers.

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Computational chemistry supports research on new semiconductor technologies

As new methods have become available for understanding and manipulating matter at its most fundamental levels, researchers working in the interdisciplinary field of materials science have been increasingly successful in synthesizing new kinds of materials. Often the goal of researchers in the field is to design materials that incorporate properties that can be useful for performing specific functi

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Car assembly is heavy work – this exoskeleton can boost your strength

Factory workers at Ford’s car assembly plants are using exoskeletons to help with their gruelling work. Leah Crane visited the factory to try one out

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Sticky and heavily armed, a tomato-relative is the new 'star' of the Brazilian inselbergs

Armed with long thorns and sticky stems, newly described plant Solanum kollastrum might look like a villain by plant standards, but a closer look on this curious new species will reveal its star-like nature in the context of its ecosystem.

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How Much Screen Time Should My Kids Get?

Our in-house Know-It-Alls answer questions about your interactions with technology.

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The Miami Rap Duo Celebrating Female Pleasure Without Apology

In the most iconic scene of the 1992 thriller Basic Instinct , the murderous novelist Catherine Tramell faces a host of detectives attempting to interrogate her. Sharon Stone, as Tramell, disarms the men—with her sexuality, most infamously, but also with the intelligence required to deploy it against them so nakedly. “I’m not stupid,” she intones, her eyes trained on the camera. Even without the

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Retailers can manipulate consumer regret to beat competitors

Markdown retailers can survive the entry of an everyday low price retailer into a highly competitive market by manipulating price, product availability, and the regret consumers feel when they pay too much or wait till a product is unavailable to buy it, according to a new study. The results explain why markdown pricing remains ubiquitous in spite of the simplicity and marketing and operational ad

8d

Toward net energy wastewater treatment using current technology

Municipal wastewater treatment in Europe consumes the energy equivalent of around two power stations per year – but could actually be generating the energy of 12. The EU-funded POWERSTEP project demonstrates how to make this more than a pipe dream.

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Image: Updated NASA damage map of Camp Fire from space

As firefighters continue to battle the destructive Camp Fire in Northern California, the Advanced Rapid Imaging and Analysis (ARIA) team at NASA's Jet Propulsion Laboratory in Pasadena, California, has produced a new map showing damage as of Nov. 16.

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When storing memories, brain prioritizes those experiences that are most rewarding

A Columbia University study finds that overnight the brain automatically preserves memories for important events and filters out the rest, revealing new insights into the processes that guide decision making and behavior.

8d

Sticky and heavily armed, a tomato-relative is the new 'star' of the Brazilian inselbergs

Heavily armed, new species of tomato genus Solanum is not the villain but the 'star' in its ecosystem in Brazil. Despite its large thorn formations and sticky stems, it turns out that newly discovered Solanum kollastrum plays important role in the life of local pollinators and is a possible food source to bat species in the region. The study was published in the open access journal PhytoKeys.

8d

Researchers developed sustainable 'nano-raspberry' to neutralize poisonous carbon monoxide

Sustainable method to neutralize poisonous carbon monoxide named 'nano-raspberry' was developed by the NITech scientists, which is a raspberry-shaped nanoparticle capable of losing the most potent toxicity of carbon monoxide.

8d

Fading stripes in Southeast Asia: First insight into the ecology of a threatened rabbit

The Annamite mountains of Vietnam and Lao PDR (Laos) harbour exceptional species richness and endemism, but its wildlife is under threat from widespread and intensive poaching. The region is home to the Annamite striped rabbit (Nesolagus timminsi), a little-known lagomorph only discovered by science in 1995. A new study carried provides the first detailed information about the species ecology. The

8d

Hyena population recovered slowly from a disease epidemic

Infectious diseases can substantially reduce the size of wildlife populations, thereby affecting both the dynamics of ecosystems and biodiversity. Predicting the long-term consequences of epidemics is thus essential for conservation. Researchers from Leibniz-IZW and CEFE have now developed a mathematical model to determine the impact of a major epidemic of canine distemper virus (CDV) on the popul

8d

An exploding meteor may have wiped out ancient Dead Sea communities

An archaeological site not far from the Dead Sea shows signs of sudden, superheated collapse 3,700 years ago.

8d

Electrical cable triggers lightweight, fire-resistant cladding discovery

A University of Melbourne researcher has led the successful development of an organic, non-combustible and lightweight cladding core—a product that was previously thought to be impossible to create.

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First insight into the ecology of an elusive and threatened rabbit

The Annamite mountains of Vietnam and Lao PDR (Laos) harbour exceptional species richness and endemism, but its wildlife is under threat from widespread and intensive poaching. The region is home to the Annamite striped rabbit (Nesolagus timminsi), a little-known lagomorph only discovered by science in 1995. A new study carried out by the Leibniz Institute for Zoo- and Wildlife Research (Leibniz-I

8d

Hyena population recovers slowly from a disease epidemic

Infectious diseases can substantially reduce the size of wildlife populations, thereby affecting both the dynamics of ecosystems and biodiversity. Predicting the long-term consequences of epidemics is thus essential for conservation. Researchers from the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) in Berlin and from the Center for Functional Ecology and Evolution (CEFE) in Montpe

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Et minuts stilhed for Kristian Rørbæk Madsen

Onsdag kl. 13 markeres Kristian Rørbæk Madsen overalt i sundhedsvæsenet med et minuts stilhed.

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Medicinrådet får nye kategorier for lægemidlers effekt

Det skal være slut med at tale om »vigtig merværdi«, mener Medicinrådet, der har lagt sig fast på syv nye kategorier for klinisk merværdi til erstatning for de seks gamle.

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Sundhedsøkonom bliver nyt medlem af Medicinrådet

Sundhedsøkonom og professor Dorte Gyrd-Hansen fra Syddansk Universitet er nyt medlem af Medicinrådet.

8d

Volcanoes and glaciers combine as powerful methane producers

Large amounts of the potent greenhouse gas methane are being released from an Icelandic glacier, scientists have discovered.

8d

The fastest way to thaw a frozen turkey—or any other food

DIY Hunks of meat, baked goods, and veggies all require different defrosting methods. If that turkey (or whatever else you’re cooking) is frozen solid, you want to get the ice out as quickly as possible. Here’s how.

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RUDN medics suggested modifications to coronary artery stenting

When coronary arteries are damaged, atherosclerotic plaques can reduce the blood supply of the heard. RUDN cardiac surgeons have developed and tested an alternative surgical technique — stenting modification — that combines the advantages of currently existing methods and has less disadvantages. Read more about the controlled clinical trial of this technique in this article in the Journal of the

8d

Is Antarctica becoming more like Greenland?

Antarctica is high and dry and mostly bitterly cold, and it's easy to think of its ice and snow as locked away in a freezer, protected from melt except around its low-lying coasts and floating ice shelves. But that view may be wrong.

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Responses of waterbirds to climate change is linked to their preferred wintering habitats

A new scientific article shows that 25 European waterbird species can change their wintering areas depending on winter weather. Warm winters allow them to shift their wintering areas northeastwards, whereas cold spells push birds southwestwards.

8d

Retailers can manipulate consumer regret to beat competitors

Markdown retailers can survive the entry of an everyday low price retailer into a highly competitive market by manipulating price, product availability, and the regret consumers feel when they pay too much or wait till a product is unavailable to buy it, according to a new study. The results explain why markdown pricing remains ubiquitous in spite of the simplicity and marketing and operational ad

8d

Electrical cable triggers lightweight, fire-resistant cladding discovery

A University of Melbourne researcher has led the successful development of an organic, non-combustible and lightweight cladding core — a product that was previously thought to be impossible to create.

8d

When it comes to love: Personality matters: QUT research

Throughout history, competitive advantages have helped men and women achieve increased success in their occupation, sport, artistic endeavors, their ability to acquire and secure resources, and ultimately, their survival. Now a study from Australia's QUT shows the same can be said for sex and procreation.

8d

Stopping cancer with a smartphone

Using an affordable, portable device that attaches to a smartphone, a University of Arizona researcher and his collaborators hope to save lives in rural Africa.

8d

When AI and optoelectronics meet: Researchers take control of light properties

Using machine-learning and an integrated photonic chip, researchers from INRS (Canada) and the University of Sussex (UK) can now customize the properties of broadband light sources. Also called "supercontinuum", these sources are at the core of new imaging technologies and the approach proposed by the researchers will bring further insight into fundamental aspects of light-matter interactions and

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