For the first time plants have been recorded making sounds when stressed. The sounds differed when they were injured or thirsty, a finding that could help farmers
Once, single-cell life claimed sole dominion over the earth. For some three billion years, unfathomable generations of unicellular organisms ate, grew and reproduced among only each other. They evolved into predators and prey, thrived and spread across the primordial waters and land, and formed complex and dynamic ecosystems in every ecological niche on the planet. Around 600 million years ago, so
Nature Communications, Published online: 05 December 2019; doi:10.1038/s41467-019-13405-w The cerebellum is critical in sensory-motor control and is structurally diverse across vertebrates. Here, the authors investigate the evolutionary relationship between locomotory mode and cerebellum architecture across squamates by integrating study of gene expression, cell distribution, and 3D morphology.
Shortly after NASA's OSIRIS-REx spacecraft arrived at asteroid Bennu, an unexpected discovery by the mission's science team revealed that the asteroid could be active, or consistently discharging particles into space.
Old habits are hard to break. A McGill-led study of replacement of traditional wood and coal burning stoves with clean energy in China suggests that, without a better understanding of the reasons behind people's reluctance to give up traditional stoves, it will be difficult for policies in China and elsewhere in the world to succeed in encouraging this shift towards clean energy. The study was pub
Simulations predict that behavioral interventions such as imposing strict no-food restrictions after meals can be as effective as strong anorectic drugs in reducing food intake in rodents, according to a study published Dec. 5 in the open-access journal PLOS Biology by Tom McGrath, Kevin Murphy and Nick Jones of Imperial College London, and colleagues.
, and this information transfer is at least partially mediated by a brain region called the anterior cingulate cortex, according to a study published Dec. 5 in the open-access journal PLOS Biology by Christian Keysers of the Netherlands Institute for Neuroscience and the University of Amsterdam, and colleagues.
A joint research team led by MAO Fangyuan from the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences and MENG Jin from the American Museum of Natural History reported a new symmetrodont, Origolestes lii, a stem therian mammal from the Early Cretaceous Jehol Biota, in China's Liaoning Province.
sci-Plex, a new cell-response screening method, pools genetically different cells and shows what happens to individual cells when the sample is treated, such as with cancer drugs. The technology collects information on changes in genetic expression in each labeled cell, providing data useful in exploring mechanisms triggered by drugs or other agents.
Researchers at the Salk Institute report the discovery of three cell types in the eye that detect light and align the brain's circadian rhythm to our ambient light. The study marks the first direct assessment in humans of light responses from these cells, called intrinsically photosensitive retinal ganglion cells (ipRGCs) — and the implications for health are substantial.
A fundamental change in our understanding of the childhood kidney cancer Wilms' tumor is on the horizon, after the discovery of its earliest genetic root by scientists at the Wellcome Sanger Institute and their collaborators. By comparing genome sequences from normal kidney tissue and tumors, the team identified patches of normal-looking kidney tissue that in fact carried DNA changes that cause Wi
Animals that evolved in environments subject to large-scale habitat-altering events like fires and storms are better equipped to handle forest fragmentation caused by human development than species in low-disturbance environments.
Animal species that have evolved, and survived, in low-disturbance environments — with little interruption from glaciation, fires, hurricanes, or anthropogenic clearing — are more sensitive to modern forest fragmentation, report Matthew Betts and colleagues.
Fossils of a previously unknown species of Early Cretaceous mammal have caught in the act the final steps by which mammals' multi-boned middle ears evolved, according to a new study.
Cameras aboard NASA's OSIRIS-REx spacecraft captured close-up shots of material being ejected from the surface of the near-Earth asteroid Bennu. The images offer a detailed look at small-scale mass loss events on an active asteroid, whereas before, observations have been limited to only the largest phenomena.
Through millions of affinity measurements, researchers have developed a biochemical model that reveals novel insights into microRNAs, which function in part to silence gene expression, but other biological functions of which are unknown.
Researchers have cleared a major obstacle in the development of an HIV vaccine, proving in animal models that effective, yet short-lasting antibodies can be coaxed into multiplying as a fighting force against the virus
Changes in magma chemistry that affect eruptive behavior occur during many volcanic eruptions, but typical analytical techniques are too slow to contribute to hazard monitoring. We used rapid energy-dispersive x-ray fluorescence analysis to measure diagnostic elements in lava samples within a few hours of collection during the 2018 Kīlauea eruption. The geochemical data provided important informa
Caldera-forming eruptions are among Earth's most hazardous natural phenomena, yet the architecture of subcaldera magma reservoirs and the conditions that trigger collapse are poorly understood. Observations from the formation of a 0.8–cubic kilometer basaltic caldera at Kīlauea Volcano in 2018 included the draining of an active lava lake, which provided a window into pressure decrease in the rese
Tissues rely on stem cells (SCs) for homeostasis and wound repair. SCs reside in specialized microenvironments (niches) whose complexities and roles in orchestrating tissue growth are still unfolding. Here, we identify lymphatic capillaries as critical SC-niche components. In skin, lymphatics form intimate networks around hair follicle (HF) SCs. When HFs regenerate, lymphatic–SC connections becom
Spin defects in silicon carbide have the advantage of exceptional electron spin coherence combined with a near-infrared spin-photon interface, all in a material amenable to modern semiconductor fabrication. Leveraging these advantages, we integrated highly coherent single neutral divacancy spins in commercially available p-i-n structures and fabricated diodes to modulate the local electrical envi
Ultrafast spectroscopies have become an important tool for elucidating the microscopic description and dynamical properties of quantum materials. In particular, by tracking the dynamics of nonthermal electrons, a material's dominant scattering processes can be revealed. Here, we present a method for extracting the electron-phonon coupling strength in the time domain, using time- and angle-resolve
Habitat loss is the primary driver of biodiversity decline worldwide, but the effects of fragmentation (the spatial arrangement of remaining habitat) are debated. We tested the hypothesis that forest fragmentation sensitivity—affected by avoidance of habitat edges—should be driven by historical exposure to, and therefore species' evolutionary responses to disturbance. Using a database containing
Single-molecule detection is a powerful method used to distinguish different species and follow time trajectories within the ensemble average. However, such detection capability requires efficient emitters and is prone to photobleaching, and the slow, nanosecond spontaneous emission process only reports on the lowest excited state. We demonstrate direct detection of stimulated emission from indiv
The Coulomb interaction generally limits the quantum propagation of electrons. However, it can also provide a mechanism to transfer their quantum state over larger distances. Here, we demonstrate such a form of electron teleportation across a metallic island. This effect originates from the low-temperature freezing of the island's charge which, in the presence of a single connected electronic cha
Adult cancers often arise from premalignant clonal expansions. Whether the same is true of childhood tumors has been unclear. To investigate whether Wilms tumor (nephroblastoma; a childhood kidney cancer) develops from a premalignant background, we examined the phylogenetic relationship between tumors and corresponding normal tissues. In 14 of 23 cases studied (61%), we found premalignant clonal
Intrinsically photosensitive retinal ganglion cells (ipRGCs) are a subset of cells that participate in image-forming and non–image-forming visual responses. Although both functional and morphological subtypes of ipRGCs have been described in rodents, parallel functional subtypes have not been identified in primate or human retinas. In this study, we used a human organ donor preparation method to
Enzyme-catalyzed reactions have begun to transform pharmaceutical manufacturing, offering levels of selectivity and tunability that can dramatically improve chemical synthesis. Combining enzymatic reactions into multistep biocatalytic cascades brings additional benefits. Cascades avoid the waste generated by purification of intermediates. They also allow reactions to be linked together to overcom
In the brain, AMPA-type glutamate receptors (AMPARs) form complexes with their auxiliary subunits and mediate the majority of fast excitatory neurotransmission. Signals transduced by these complexes are critical for synaptic plasticity, learning, and memory. The two major categories of AMPAR auxiliary subunits are transmembrane AMPAR regulatory proteins (TARPs) and cornichon homologs (CNIHs); the
Active asteroids are those that show evidence of ongoing mass loss. We report repeated instances of particle ejection from the surface of (101955) Bennu, demonstrating that it is an active asteroid. The ejection events were imaged by the OSIRIS-REx (Origins, Spectral Interpretation, Resource Identification, and Security–Regolith Explorer) spacecraft. For the three largest observed events, we esti
Vaccine induction of broadly neutralizing antibodies (bnAbs) to HIV remains a major challenge. Germline-targeting immunogens hold promise for initiating the induction of certain bnAb classes; yet for most bnAbs, a strong dependence on antibody heavy chain complementarity-determining region 3 (HCDR3) is a major barrier. Exploiting ultradeep human antibody sequencing data, we identified a diverse s
Tang et al . (Research Articles, 10 August 2018, p. 570) report on the properties of Dirac fermions with both on-site and Coulomb interactions. The substantial decrease, up to ~40%, of the Fermi velocity of Dirac fermions with on-site interaction is inconsistent with the numerical data near the Gross-Neveu quantum critical point. This results from an inappropriate finite-size extrapolation.
Hesselmann et al . question one of our conclusions: the suppression of Fermi velocity at the Gross-Neveu critical point for the specific case of vanishing long-range interactions and at zero energy. The possibility they raise could occur in any finite-size extrapolation of numerical data. Although we cannot definitively rule out this possibility, we provide mathematical bounds on its likelihood.
Lava flows present a recurring threat to communities on active volcanoes, and volumetric eruption rate is one of the primary factors controlling flow behavior and hazard. The time scales and driving forces of eruption rate variability, however, remain poorly understood. In 2018, a highly destructive eruption occurred on the lower flank of Kīlauea Volcano, Hawai'i, where the primary vent exhibited
A device that releases synthetic hormones slowly over time could one day provide a more practical alternative to daily birth control pills, say scientists.
A joint research team led by Mao Fangyuan from the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences and Meng Jin from the American Museum of Natural History reported a new symmetrodont, Origolestes lii, a stem therian mammal from the Early Cretaceous Jehol Biota, in China's Liaoning Province.
Nedskæringer i de tværfaglige teams på hospitalerne har gjort, at skolelærernes bidrag i udredningen af børn med socialpædiatriske problemstillinger er endnu vigtigere, mener formand for Dansk Pædiatrisk Selskab.
A hundred and twenty million years ago, when northeastern China was a series of lakes and erupting volcanoes, there lived a tiny mammal just a few inches long. When it died, it was fossilized down to its most miniscule ear bones . And it is these ear bones that have so intrigued scientists: They are evidence of how evolution created the unique ear of mammals, giving modern mammals—including us—a
23Mofang, a Chinese DNA testing startup that's highly similar to 23andMe — down to its name — is giving customers some interesting results. Notably, it totally missed Bloomberg reporter K. Oanh Ha's predominately Vietnamese heritage. That's because the company relies entirely on a pool of genetic data from Chinese participants, according to Bloomberg , so ancestry reports only trace people's DNA
Nature, Published online: 05 December 2019; doi:10.1038/d41586-019-03725-8 Gut neurons that trigger unpleasant symptoms also rally the body's defenses against Salmonella.
Researchers have found that some corals are more likely to eat microplastics when they consume other food, but they don't have a taste microplastics alone. Two coral species tested responded differently to the synthetic material, suggesting variations in how corals adapt to life with microplastics, according to a new study published in Scientific Reports . Tiny microplastic particles are about as
While e-cigarettes are still the most popular, teens are also using other items like little flavored cigars — a worrisome sign for nicotine addiction, the C.D.C. says.
As the year comes to a close, it's time to take a look at some of the most memorable events and images of 2019. Events covered in this essay (the last of a three-part photo summary of the year) include pro-democracy demonstrations in Hong Kong, anti-government protests in Chile and Iraq, a toxic sky over New Delhi, an all-female team of spacewalkers, a planned "storming" of Area 51, the aftermath
SpaceX launched a 3-ton shipment to the International Space Station on Thursday, including "mighty mice" for a muscle study, a robot sensitive to astronauts' emotions and a miniature version of a brewery's malt house.
A random conversation between two Cornell researchers at a child's birthday party led to a collaboration and new understanding of how bacteria resist toxins, which may lead to new tools in the fight against harmful infections.
A random conversation between two Cornell researchers at a child's birthday party led to a collaboration and new understanding of how bacteria resist toxins, which may lead to new tools in the fight against harmful infections.
The first flowering plants originated more than 140 million years ago in the early Cretaceous. They are the most diverse plant group on Earth with more than 300,000 species. Evolutionary biologists have now analyzed 3-dimensional models of flowers and found that flower shapes can evolve in a modular manner in adaptation to distinct pollinators.
Howling wind drives torrential rain sideways as tall, slender palms bow and tree limbs snap. A hurricane approaches, its gale-force winds wreaking havoc as it nears the coast. Storm surges combine with the downpour, inundating the area with water.
Move over Godzilla vs. King Kong—this is the crossover event you've been waiting for. Well, at least if you're a condensed matter physicist. Harvard University researchers have demonstrated the first material that can have both strongly correlated electron interactions and topological properties. Not entirely sure what that means? Don't worry, we'll walk you through it. All you need to know right
Two Classes Uber has repeatedly argued that its drivers are independent contractors rather than employees — a distinction that lets the company get away with not paying them an hourly wage or providing them with benefits. And it now seems Uber's efforts to make sure drivers know they're not employees even extends — bizarrely — to where they're allowed to use the bathroom. Very Strange Uber operat
The comet, 2I/Borisov, looks surprisingly like comets closer to home. It's a sign that the processes that formed the sun and planets are at work elsewhere in the universe. (Image credit: NASA, ESA and D. Jewitt (UCLA))
The creation of photoelectrons through ionisation is one of the most fundamental processes in the interaction between light and matter. Yet, deep questions remain about just how photons transfer their linear momentum to electrons. With the first sub-femtosecond study of the linear photon momentum transfer during an ionisation process, ETH physicists provide now unprecedented insight into the birth
A team of Florida State University researchers studying new methods to remove toxic heavy metals from biosolids—the solid waste left over after sewage treatment—found the key is a brief spin through a microwave.
Our french fry stores are resilient. (DepositPhoto/) Potatoes: boil 'em, mash 'em, stick 'em in a stew . Or don't, because they're in dangerously short supply. A late start to the growing season combined with an unusually cold, wet autumn damaged potato crops in the US and Canada, leaving french fry makers hunting around for spuds with which to make their wares. But don't get too worried. Experts
Nature, Published online: 05 December 2019; doi:10.1038/d41586-019-03769-w Provocative analysis of sea-floor cores suggests that quakes on the Cascadia fault off California can trigger tremors on the San Andreas.
We've seen artist-in-residence programs in a number of the towns we've visited. The first was in Eastport, Maine, where we ran into Richelle Gribble , a young artist based in Los Angeles, whom I consider an resident-artist extraordinaire. Over the past three and a half years, Richelle (as I'll refer to her) has been an artist-in-residence in 15 different programs around the world, from a biospher
A cluster of industrial chemicals known by the shorthand term "PFAS" has infiltrated the far reaches of our planet with significance that scientists are only beginning to understand.
According to a much-debated geo-engineering approach, both sea-ice retreat and global warming could be slowed by using millions of wind-powered pumps, drifting in the sea ice, to promote ice formation during the Arctic winter. AWI researchers have now, for the first time, tested the concept using a complex climate model and published their findings in the journal Earth's Future. Their verdict is s
NASA provided analyses of Typhoon Kammuri's heavy rainfall on its track through the Northwestern Pacific Ocean using the Global Precipitation Measurement mission or GPM core satellite.
Flowering plants are characterized by an astonishing diversity of flowers of different shapes and sizes. This diversity has arisen in adaptation to selection imposed by different pollinators including, among others, bees, flies, butterflies, hummingbirds, bats or rodents. Although several studies have documented that pollinators can impose strong selection pressures on flowers, our understanding o
Canadians spend a lot of money around this time of year, on gifts, food, entertainment and travel. In its annual study of holiday season spending habits, the accounting firm PwC estimates that the average Canadian consumer will drop close to $1,600 in 2019.
Researchers have identified how damaged DNA molecules get repaired inside the human genome. The discovery offers new insights into how the body works to ensure its health and how it responds to diseases that stem from impaired DNA. "Our findings show that a DNA repair process is very robust, engineered through intricate structural and dynamical signatures where breaks occur," explains senior auth
Flowering plants are characterized by an astonishing diversity of flowers of different shapes and sizes. This diversity has arisen in adaptation to selection imposed by different pollinators including, among others, bees, flies, butterflies, hummingbirds, bats or rodents. Although several studies have documented that pollinators can impose strong selection pressures on flowers, our understanding o
According to a much-debated geo-engineering approach, both sea-ice retreat and global warming could be slowed by using millions of wind-powered pumps, drifting in the sea ice, to promote ice formation during the Arctic winter.
Greenhouse gas emissions released directly from the movement of volcanic rocks are capable of creating massive global warming effects — a discovery which could transform the way scientists predict climate change, a new study reveals.
A biotech firm called Libella Gene Therapeutics claims that the genetic treatment it's currently developing can reverse aging by as many as 20 years. For an eye-popping price of $1 million, the company will offer an experimental treatment to elderly customers that the company says will extend their telomeres — structures that sit at the end of our chromosomes like protective caps, but gradually s
PLUS. En af den matematiske fysiks fremmeste har gennem mange år fremført sin halvfærdige teori om et cyklisk univers. I sidste uge var Roger Penrose i København.
A random conversation between two Cornell researchers at a child's birthday party led to a collaboration and new understanding of how bacteria resist toxins, which may lead to new tools in the fight against harmful infections.
A study by researchers at The Ohio State University Wexner Medical Center finds a new diagnostic method that provides doctors with a 'virtual biopsy' that allows them to definitively diagnose cysts in the pancreas and eliminate those that pose a risk of cancer.
A new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against human cancer cells grown in the laboratory and in mice, according to a study by researchers at the Stanford University School of Medicine.
Protein levels in people's blood can predict their age, a Stanford study has found. The study also found that aging isn't a smoothly continuous process.
Even models in the 1970s accurately predicted the relationship between greenhouse gas emissions and temperature rise — Read more on ScientificAmerican.com
Umeåfysiker Alexandr Talyzin i samarbete med Technical University of Dresden och Chalmers University är först med att visa på hög stabilitet hos det porösa nanomaterialet COFs. Studien är publicerad i Angewandte Chemie. Det porösa nanomaterial som kallas COFs (Covalent Organic Frameworks) är en bred familj av polymerer bestående av endast lätta grundämnen. Frånvaron av metallatomer i sin struktur
Potatoes are important. They rank fourth among the world's staple crops. In the United States, they are grown commercially in 30 states and valued at $4 billion annually. Potatoes are also susceptible to 160 different fungal, bacterial, and viral diseases, such as blackleg and soft rot diseases, which are caused by the bacterium Dickeya dianthicola.
Potatoes are important. They rank fourth among the world's staple crops. In the United States, they are grown commercially in 30 states and valued at $4 billion annually. Potatoes are also susceptible to 160 different fungal, bacterial, and viral diseases, such as blackleg and soft rot diseases, which are caused by the bacterium Dickeya dianthicola.
Scientists found that women who use permanent hair dye and chemical hair straighteners have a higher risk of developing breast cancer than women who don't use these products. The study suggests that breast cancer risk increased with more frequent use of these chemical hair products.
Researchers studying the brain found that women taking oral contraceptives, commonly known as birth control pills, had significantly smaller hypothalamus volume, compared to women not taking the pill, according to a new study.
Contrary to accepted knowledge, blood can bring more oxygen to mice brains when they exercise because the increased respiration packs more oxygen into the hemoglobin, according to an international team of researchers who believe that this holds true for all mammals.
As a content moderator for Facebook, it was literally Dublin resident Chris Gray's job to watch child abuse, animal torture, and executions — disturbing imagery that left his mental health in shambles. "You would wake up and you're remembering the video of someone machine-gunning people in the Middle East somewhere," he told The Guardian , "trying to think whether there was an ISIS flag, and so w
Nature, Published online: 05 December 2019; doi:10.1038/d41586-019-03777-w Most forecasts published between 1970 and 2007 did a good job of predicting global warming. Plus: NASA's daring solar probe discovers the secrets of the solar wind and cell biologists visualize a world of a thousand dimensions.
'We hope Uniqprimer and the tests it designed will aid in the accurate detection of D. dianthicola and many other pathogens,' said lead author Shaista Karim. 'Accurate pathogen detection is the first step for management of a disease, which helps in reducing the losses in the potato industry and informing the farmers in a timely manner to better aid on-farm decision making.'
Extensive evidence from HIV prevention research studies has firmly established that 'Undetectable Equals Untransmittable,' or U=U. This means that people living with HIV who achieve and maintain an undetectable viral load–the amount of virus in their blood–by taking antiretroviral therapy (ART) as prescribed do not sexually transmit HIV to others. The CDC estimates this strategy is 100% effectiv
A team of scientists has identified how damaged DNA molecules are repaired inside the human genome, a discovery that offers new insights into how the body works to ensure its health and how it responds to diseases that stem from impaired DNA.
Study finds coronary heart disease (CHD) patients who include Transcendental Meditation (TM) with cardiac rehabilitation (CR) increased blood flow to the heart by 20.7%. This was the first study to show TM significantly enhanced lifestyle modification in patients, and the first to use positron emission tomography (PET) to measure their effect on cardiac function and rehabilitation. The NIH-funded
Preventing chronic disease could help curb the opioid epidemic, according to research from the University of Georgia. The study is the first to examine the relationship between hospitalizations due to opioid misuse and chronic disease.
Harvard University researchers have demonstrated the first material that can have both strongly correlated electron interactions and topological properties, which not only paves the way for more stable quantum computing but also an entirely new platform to explore the wild world of exotic physics.
Say hello to macOS Catalina, which manages your content in a more specialized and efficient way. (David Nield/) With the arrival of macOS Catalina , iTunes is no more—on the Mac, at least. The long-running app that once housed all content for Apple devices has now been replaced by three separate and specialized apps: Music, TV, and Podcasts. These apps aren't hugely different from what iTunes use
Signs of cardiac stress that appear in the blood after exercise can indicate which patients with coronary artery disease are most at risk of heart attack or other issues, researchers report. Identifying patients with otherwise stable coronary artery disease (CAD) who are high-risk and would benefit from more intense or invasive interventions is currently a major theme in cardiology research. Ofte
När proteiner i hjärnan bildar fällningar till olösliga aggregat kan sjukdomar som till exempel Alzheimers eller Parkinsons uppstå. En forskargrupp i Göteborg har kommit ett steg närmare till att förstå denna process. Parkinsons sjukdom är en progressiv neurologisk sjukdom som kännetecknas av rörelseproblem, stelhet och skakningar. När proteinet alfa-synuklein klumpar ihop sig till aggregat i hjä
With Kamala Harris's unexpected departure from the presidential race Tuesday, the lineup of the next primary debate has become something the Democratic Party as a whole decidedly is not: all white. With Tulsi Gabbard and Andrew Yang yet to qualify, and Cory Booker and Julían Castro unlikely to, the debate stage will be notably lacking in ethnic diversity. For a political party—and a country—whose
A team of computer science professors at BYU created a method to quickly resize animations of fluids without having to completely re-simulate the entire sequence.
Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.
There's an assumption that sugars are all bad, but a study led by researchers at St. Michael's Hospital suggests that the impact of sugars on heart health depends on the dose and type of sugar consumed. Led by Dr. John Sievenpiper, the team conducted a review of previous studies investigating the association between reported intakes of sugars and heart disease. The team found that that sugars beha
The creation of photoelectrons through ionisation is one of the most fundamental processes in the interaction between light and matter. Yet, deep questions remain about just how photons transfer their linear momentum to electrons. With the first sub-femtosecond study of the linear photon momentum transfer during an ionisation process, physicists at ETH Zurich provide now unprecedented insight into
A team of Florida State University researchers studying new methods to remove toxic heavy metals from biosolids — the solid waste left over after sewage treatment — found the key is a brief spin through a microwave.
The largest brain imaging study of children ever conducted in the United States has revealed structural differences in the brains of those whose parents have depression.
A new article in Annals of Allergy, Asthma and Immunology shows a significant association between multiple prenatal and early life exposures to indoor pollutants and the degree of allergic sensitivity in 2-year-olds.
A study by researchers at Woods Hole Oceanographic Institution (WHOI) shows that the microbial communities inside whales may play an important role in the digestion of one of the ocean's most abundant carbon-rich lipids, known as a wax ester.
Patients with castration-resistant prostate cancer (CRPC) have a poor clinical response to drugs for CRPC, including enzalutamide. Recently, an mRNA splice variant of the androgen receptor (AR), called AR-V7, that lacks a functional ligand-binding domain has been highlighted as a major resistance mechanism in CRPC. This important study describes a novel mechanism for down-regulation of AR-V7 by mi
Music is an art, but it is also a science involving vibrating reeds and strings, sound waves and resonances. The study of acoustics can help scientists produce beautiful music even with musical instruments fashioned with high-tech methods, such as 3D printing. Researchers studied the sound quality of a 3D-printed ukulele and compared it to a standard wooden instrument, and will present the group's
Refined instruments reduce noise at the quantum level, allowing for discoveries of more distant gravitational waves. grav_wave_4.jpg This is a view of the LIGO detector in Hanford, Washington. Image credits: LIGO Laboratory Physics Thursday, December 5, 2019 – 12:00 Ramin Skibba, Contributor (Inside Science) — Physicists have successfully developed a new instrument that significantly reduces qu
A team of engineers has developed an automated way to produce polymers, making it much easier to create advanced materials aimed at improving human health. The innovation is a critical step in pushing the limits for researchers who want to explore large libraries of polymers, including plastics and fibers, for chemical and biological applications such as drugs and regenerative medicine through tis
A team of engineers has developed an automated way to produce polymers, making it much easier to create advanced materials aimed at improving human health. The innovation is a critical step in pushing the limits for researchers who want to explore large libraries of polymers, including plastics and fibers, for chemical and biological applications such as drugs and regenerative medicine through tis
As the EPA gets closer to finalizing changes to an Obama-era air pollution rule, a group of former agency advisers says the Trump administration's attempt to weaken the mercury emissions regulations is based on faulty and outdated data.
Two months of relentless rains have submergedvillages and farms and sent rivers of mud crashing into houses across East Africa, with at least 265 killed, according to an AFP tally, as meteorologists warn of more to come.
Nuclear physics usually involves high energies, as illustrated by experiments to master controlled nuclear fusion. One of the problems is how to overcome the strong electrical repulsion between atomic nuclei which requires high energies to make them fuse. But fusion could be initiated at lower energies with electromagnetic fields that are generated, for example, by state-of-the-art free electron l
The Graphene Flagship brought together top European researchers and companies to discuss the most disruptive ways graphene could enhance composites used in the aerospace, automotive and energy industries. The multidisciplinary team involved researchers from academic institutions, business enterprises such as Graphene Flagship Partners Nanesa and Avanzare, and large transportation end-user industri
According to a much-debated geo-engineering approach, both sea-ice retreat and global warming could be slowed by using millions of wind-powered pumps, drifting in the sea ice, to promote ice formation during the Arctic winter.
NASA provided analyses of Typhoon Kammuri's heavy rainfall on its track through the Northwestern Pacific Ocean using the Global Precipitation Measurement mission or GPM core satellite.
The first flowering plants originated more than 140 million years ago in the early Cretaceous. They are the most diverse plant group on Earth with more than 300,000 species. In a new study in Communications Biology, evolutionary biologists around Agnes Dellinger and Jürg Schönenberger from the University of Vienna have analysed 3-dimensional models of flowers and found that flower shapes can evolv
A new paper out of Concordia's John Molson School of Business suggests that spending some of that money on green products might make consumers feel quite a bit better about their purchases.The study looks at the so-called "greenconsumption effect" — how using a green product creates a "warm glow" feeling in users — and what it means for retailers in an increasingly eco-conscious marketplace.
Researchers at the McKelvey School of Engineering have devised a new imaging technique based on a technology that has been used for two decades in ophthalmology that can provide accurate, real-time, computer-aided diagnosis of colorectal cancer.
Insilico Medicine announced the publication of a comprehensive review of the deep biomarkers of aging and the publication of a granted patent titled 'Deep transcriptomic markers of human biological aging and methods of determining a biological aging clock.'
This systematic review and first meta-analysis on the prevalence of traumatic brain injury (TBI) in people who are homeless or in unstable housing situations — including 38 studies published between 1995 and 2018, and published in The Lancet Public Health journal — suggests that homeless people experience a disproportionately high lifetime prevalence of TBI.
The observational and modelling study which used individual-level data from almost 400,000 people, published in The Lancet, extends existing research because it suggests that increasing levels of non-HDL cholesterol may predict long-term cardiovascular risk by the age of 75 years. Past risk estimates of this kind are based on 10-year follow-up data.
What on Earth was the point of the first day of the House Judiciary Committee hearings on impeachment? The House Intelligence Committee hearings in November told a coherent story. Public-spirited career personnel and a Purple Heart Army officer were aligned on one side; venal and untruthful political operatives aligned on the other. Each witness was called for a reason. A televised hearing in a h
A special committee of California lawmakers gathered Tuesday, for the first time in five years, to discuss sea level rise and what the state needs to do to better prepare coastal communities from devastating loss.
Ommochromes, the pigments that colour the skin of squids and other invertebrates, could be used in the food and health sectors for their antioxidant and antimicrobial properties. This is confirmed by analyses carried out by researchers from the University of Sonora in Mexico and the Miguel Hernández University in Spain.
Researchers at the Institute of Biotechnology, University of Helsinki, have uncovered multi-level relationships between locomotion—the ways animals move—and brain architecture, using high-definition 3-D models of lizard and snake brains.
Scientists are sending mighty mice to space, but rather than being gym rats, their strength was enhanced through genetic experimentation in the hopes of preventing human astronauts from experiencing muscle loss in microgravity.
Every chemical, from the simplest to the most complex, have a structural skeleton of atoms. The atoms can be added or removed to transform the chemical into different types, for use in different applications. For many pharmaceutical and agricultural chemicals, the skeleton consists of a multi-membered carbon ring called a carbocycle.
Ommochromes, the pigments that colour the skin of squids and other invertebrates, could be used in the food and health sectors for their antioxidant and antimicrobial properties. This is confirmed by analyses carried out by researchers from the University of Sonora in Mexico and the Miguel Hernández University in Spain.
Researchers at the Institute of Biotechnology, University of Helsinki, have uncovered multi-level relationships between locomotion—the ways animals move—and brain architecture, using high-definition 3-D models of lizard and snake brains.
Ever since I was very young, I have been enamored of elegant mathematics. Like many people of a similar bent, I agreed completely with Eugene Wigner's famous article "The Unreasonable Effectiveness of Mathematics in the Natural Sciences," in which the Nobel Prize-winning physicist discusses how elegant mathematics has been "unreasonably" successful in explaining physical law. Wigner further state
Virtual Eden When a Roman Catholic priest made a Vatican-themed Minecraft server, he meant for it to be an online haven where people could hang out free from internet toxicity. Instead, trolls descended, immediately overwhelming the server with a DDOS attack, Business Insider reports . And while internet trolls, especially on Minecraft , are far from new, it's bizarre to see the Vatican get wrapp
Older adults who 'train' for a major operation by exercising, eating a healthy diet, and practicing stress reduction techniques preoperatively have shorter hospital stays and are more likely to return to their own homes afterward rather than another facility, compared with similar patients who do not participate in preoperative rehabilitation, according to research findings.
The introduction of a performance-related financial incentive scheme for GPs led to a dramatic almost 5-fold rise in the number of patients whose heart rhythm condition was said to have been 'cured'.
Researchers hope put to rest a century-old scientific debate by demonstrating that the low-level organism S. roeseli is capable of decision making. They also offer the video evidence to prove it.
Ommochromes, the pigments that color the skin of squids and other invertebrates, could be used in the food and health sectors for their antioxidant and antimicrobial properties. This is confirmed by the analyses carried out by researchers from the University of Sonora in Mexico and the Miguel Hernández University in Spain.
Nuclear physics usually involves high energies, as illustrated by experiments to master controlled nuclear fusion. One problem is how to overcome the strong electrical repulsion between atomic nuclei which requires high energies to make them fuse. But fusion could be initiated at lower energies with electromagnetic fields that are generated by state-of-the-art free electron lasers emitting X-ray l
Young patients with inflammatory bowel disease (IBD) are five times more likely than the general population to develop viral infections that can lead to hospitalisation or permanent organ damage, a new study published in the UEG Journal has found.
Taking Credit Back in September, the Indian Space Research Organization announced that it had found its Vikram lander, which it had lost contact with days earlier as it prepared to land on the Moon — and said it was trying to reestablish contact with the lost lander. Months later, NASA made a similar announcement : that it had spotted the wreckage of the lander, with the help of amateur space ent
The slaughter of half of China's pigs due to the African swine fever virus raging across Asia and Europe has helped drive world food prices to a two-year high
A research team has reported seeing, for the first time, atomic scale defects that dictate the properties of a new and powerful semiconductor. The study, published earlier this month in the journal Physical Review X, shows a fundamental aspect of how the semiconductor, beta gallium oxide, controls electricity.
Cleveland Clinic researchers have found that using lungs from donors who are considered high risk for certain infectious diseases compared to standard risk donors results in similar one-year survival for recipients. In addition, researchers saw no difference in rejection or graft (donor lung) survival after one year in patients receiving lungs from increased-risk donors.
The tropical disease Leishmaniasis is being tackled by catching female sand flies who carry the parasite that causes the disease in both dogs and humans.Insecticide-impregnated dog collars and dog culling are used in Brazil but instead, researchers used a 'lure to kill' method by attracting female flies towards insecticide using the male pheromome.This reduced female sandflies by 49% compared with
When cells are stressed, they initiate a complex and precisely regulated response to prevent permanent damage. One of the immediate reactions to stress signals is a reduction of protein synthesis (translation). Until now, it was difficult to measure such acute cellular changes. As reported in the latest online issue of the renowned journal Molecular Cell, researchers at Goethe University have now
Sticks and stones may break one's bones, but healing them requires the production of a protein signal that stimulates the generation, growth and spread of vital nerve cells, or neurons, throughout the injured area. That's the finding of a recent Johns Hopkins Medicine study that used mice to demonstrate what likely takes place during human fracture repair as well.
A mutated gene found in people with intellectual disabilities that could be targeted for treatment has been identified by an international team including University of Queensland researchers.
Scientists have discovered why a specific genetic mutation causes intellectual disability and autism spectrum disorder in children. The mutation results in fewer brain synapses, making it harder for the brain to learn. The discovery offers a new target for treatment.
Pioneering experiments using heated field plots to test the responses of crops to temperature have revealed an unexpected plus side of climate change for farmers.
Researchers from the Salk Institute and the UC San Diego School of Medicine found that a 10-hour time-restricted eating intervention, when combined with traditional medications, resulted in weight loss, reduced abdominal fat, lower blood pressure and cholesterol for participants. The pilot study, published in Cell Metabolism on Dec. 5, 2019, could lead to a new treatment option for metabolic syndr
For patients with HIV, CD4 counts reflect the health of their immune system and HIV RNA levels indicate their viral load. This observational study focused on how cancer treatments were associated with those two important clinical measures and risk of death in nearly 200 patients with HIV and cancer.
Cell phones are mainstays of daily life. This observational study analyzed 20 years of data on people who went to emergency departments with head and neck injuries from cell phone use to estimate the number of injuries, learn what types of injuries there were, and understand how the injuries occurred, such as from distracted driving or walking.
High-intensity group workout classes are increasingly popular at fitness centers. While research has shown that these workouts can have cardiovascular and other benefits, few studies have been conducted on whether they lead to more injuries.
Bats face many threats — from habitat loss and climate change to emerging diseases, such as white-nose syndrome. But it appears that wildfire is not among those threats, suggests a study from the University of California, Davis.
One of the first things viewers of 'Rick and Morty' might notice about Rick is his penchant for punctuating his speech with burps. Brooke Kidner has analyzed the frequency and acoustics of belching while speaking, and by zeroing in on the specific pitches and sound qualities of a midspeech burp, aims to find what latent linguistic meaning might be found in the little-studied gastrointestinal grumb
Bats respond to wildfires in the Sierra Nevada Mountains in varied but often positive ways, a study in Scientific Reports suggests. The findings could help to improve bat conservation and management strategies in fire-prone forest regions.
In an effort to replicate an experiment conducted over a century ago, researchers at Harvard Medical School present evidence confirming at least one single-cell organism — the trumpet-shaped Stentor roeselii — exhibits a hierarchy of avoidance behaviors. Exposed repeatedly to the same stimulation, the organism can in effect 'change its mind' about how to respond, indicating a capacity for relati
Herbivorous dinosaurs evolved many times during the 180 million-year Mesozoic era, and while they didn't all evolve to chew, swallow, and digest their food in the same way, a few specific strategies appeared time and time again. An investigation of the skulls of 160 non-avian dinosaurs revealed the evolution of common traits in the skulls and teeth of plant-eating members of otherwise very differe
In a study publishing Dec. 5 in the journal Cell Metabolism, researchers for the first time looked at the effects of TRE in people who had been diagnosed with metabolic syndrome and therefore were at a higher risk of diabetes, heart disease, and stroke. The investigators found that when participants restricted their eating to 10 hours or less over a period of 12 weeks, they lost weight and some sy
More than 100 years ago, zoologist Herbert Spencer Jennings described surprisingly varied avoidance behaviors in the single-celled freshwater protist Stentor roeseli. When later experiments in a related organism failed to reproduce what he'd seen, his claims were discredited. Now, a report publishing in the journal Current Biology on Dec. 5 confirms what Jennings witnessed all those years ago: obs
En læser husker de dejligt barndomsbesøg hos mormor i Sverige, hvor morgenmaden bestod af syrnet Långfil. Kan man selv lave det? Chefkonsulent i Mejeriforeningen giver opskriften.
Bats face many threats—from habitat loss and climate change to emerging diseases, such as white-nose syndrome. But it appears that wildfire is not among those threats, suggests a study from the University of California, Davis, published today in the journal Scientific Reports. It found that bats in the Sierra Nevada appear to be well-adapted to wildfire.
Pioneering experiments using heated field plots to test the responses of crops to temperature have revealed an unexpected plus side of climate change for farmers.
Just how far will Republicans go in following President Donald Trump's embrace of Russia? An answer may be crystallizing as the GOP mobilizes its defense of the president against impeachment. Both congressional Republicans and conservative commentators are defending Trump from impeachment partly by accusing Ukraine of intervening against him in the 2016 presidential election—despite repeated warn
Defunct satellite capture options include net, harpoon or embrace with mechanical arms The European Space Agency is working to tackle the issue of space debris with the technological version of a big hug. It hopes to be able to use tentacle-like mechanical arms to embrace a dead satellite and remove it from orbit. Continue reading…
Step into artist Cornelia Geppert's visually stunning video game "Sea of Solitude," which explores how battling the "monsters" of loneliness and self-doubt can help us better grapple with the complexity and struggles of mental health.
Once, single-cell life claimed sole dominion over the earth. For some three billion years, unfathomable generations of unicellular organisms ate, grew and reproduced among only each other. They evolved into predators and prey, thrived and spread across the primordial waters and land, and formed complex and dynamic ecosystems in every ecological niche on the planet. Around 600 million years ago, so
Bats face many threats—from habitat loss and climate change to emerging diseases, such as white-nose syndrome. But it appears that wildfire is not among those threats, suggests a study from the University of California, Davis, published today in the journal Scientific Reports. It found that bats in the Sierra Nevada appear to be well-adapted to wildfire.
Just a year ago, the National Science Foundation-funded Laser Interferometer Gravitational-wave Observatory, or LIGO, was picking up whispers of gravitational waves every month or so. Now, a new addition to the system is enabling the instruments to detect these ripples in space-time nearly every week.
Pioneering experiments using heated field plots to test the responses of crops to temperature have revealed an unexpected plus side of climate change for farmers.
Herbivorous dinosaurs evolved many times during the 180 million-year Mesozoic era, and while they didn't all evolve to chew, swallow, and digest their food in the same way, a few specific strategies appeared time and time again. An investigation of the skulls of 160 non-avian dinosaurs revealed the evolution of common traits in the skulls and teeth of plant-eating members of otherwise very differe
One of the first things new viewers of the cartoon "Rick and Morty" might notice about Rick Sanchez is his penchant for punctuating his speech with burps. Linguistics can provide a new way to read into the dimension-hopping grandfather's midsentence belching.
The Graphene Flagship brought together top European researchers and companies to discuss the most disruptive ways graphene could enhance composites used in the aerospace, automotive and energy industries.
Members of a polar research expedition have provided researchers from Charité – Universitätsmedizin Berlin and the Max Planck Institute for Human Development with an opportunity to study the effects of social isolation and extreme environmental conditions on the human brain. The researchers found changes to the dentate gyrus, an area of the hippocampus responsible for spatial thinking and memory.
VM i Åre respektive Östersund 2019 gav stora ekonomiska och sociala effekter. Turister som besökte VM-evenemangen spenderade drygt 1 500 kr per dag. Samtidigt var andelen stolta länsbor större ju längre avståndet var till evenemangen. Det visar studie från turismforskningscentret ETOUR. I en stor VM-studie konstaterar forskarna att den totala ekonomiska effekten av världsmästerskapen i alpint och
För män med prostataproblem var kastrering länge en behandlingsmetod. Men besluten om kastrering i början av 1900 grundade sig i att man trodde att mannens prostata motsvarade kvinnans livmoder. En ny avhandling från Linköpings universitet vänder på föreställningen om mannen som norm i medicinhistorien. Många män vet att godartad prostataförstoring kan påverka livskvaliteten. Prostatan, som norma
Genes have been identified that confer resistance to multiple leaf rust species in barley. The findings by an international team, led by KAUST researchers, could transform the breeding of durable disease-resistant cereal crops and help support efforts to improve global food security.
Genes have been identified that confer resistance to multiple leaf rust species in barley. The findings by an international team, led by KAUST researchers, could transform the breeding of durable disease-resistant cereal crops and help support efforts to improve global food security.
Nature, Published online: 05 December 2019; doi:10.1038/d41586-019-03773-0 The thesis a central element of how graduate students are assessed. But is it time for an overhaul? Julie Gould finds out.
Researchers at LSTM have genetically modified malaria carrying mosquitoes in order to demonstrate the role of particular genes in conferring insecticide resistance.
A new effective treatment of hepatitis C not only combats the virus, but is also effective against potentially fatal complications such as reduced liver functioning and cirrhosis. This is the result of a new study from Aarhus University.
Researchers at the Institute of Biotechnology, University of Helsinki, have uncovered multi-level relationships between locomotion – the ways animals move – and brain architecture, using high-definition 3D models of lizard and snake brains.
The amount of food needed to feed the world's population in the future is of vital importance. Researchers at the University of Göttingen have now analysed how much extra food people are likely to eat taking into account bigger bodies as well as a rising population. They modelled increases in body size by looking at data on increasing BMI in Mexico and height in the Netherlands. The results were p
Warm-sector heavy rainfall (WSHR) events often cause severe flooding, huge economic losses, and many casualties, but the operational prediction of these events is difficult and often inaccurate. A study summarizes existing researches and propose challenges presented by WSHR.
Thanks to a newly developed laser spectrometer, Empa researchers can for the first time show which processes in grassland lead to nitrous oxide emissions. The aim is to reduce emissions of this potent greenhouse gas by gaining a better understanding of the processes taking place in the soil.
Warm-sector heavy rainfall (WSHR) is a type of rainstorm proposed by Chinese meteorologists that had been found to only occur in South China. However, WSHR has also been found in other regions of China, according to Prof. Jianhua Sun from the Institute of Atmospheric Physics (IAP) of the Chinese Academy of Sciences.
Wildfire is a natural process in the forests of the western US, and many species have evolved to tolerate, if not benefit from it. But wildfire is changing. Research in the journal Biological Conservation, published by Elsevier, suggests fire, as it becomes more frequent and severe, poses a substantial risk to goshawks in the Sierra Nevada region.
Wildfire is a natural process in the forests of the western US, and many species have evolved to tolerate, if not benefit from it. But wildfire is changing. Research in the journal Biological Conservation, published by Elsevier, suggests fire, as it becomes more frequent and severe, poses a substantial risk to goshawks in the Sierra Nevada region.
It will be one of the most daunting, complicated and, potentially, scientifically rewarding missions ever undertaken to the red planet. Ministers at a recent meeting of the European Space Agency (ESA) have fully committed to plans to collect samples from the surface of Mars and return them to Earth, in a joint effort with NASA. Official approval for the NASA budget to cover this mission is anticip
rr Score a small victory for common sense. BMW is dropping the $80 annual fee it charges owners to plug in and use their Apple iPhones via Apple CarPlay, a charge BMW extorts – sorry, extracts – even though Apple charges BMW no ongoing licensing fee BMW has to recoup. (In case there isn't enough margin in cars costing $35,000 to $150,000.) BMW said this week the fee will no longer be charged. BMW
The reward pathway of the brain causes feelings of happiness but is also involved in behavioral disorders like schizophrenia and addiction. A breakthrough study by scientists in Japan has now identified the role of a protein called Npas4 in the reward pathway, mediated by the well-known proteins MAPK and CBP, opening doors to potential therapies for associated disorders. Cocaine-treated mice with
Only 8% of Americans survive cardiac arrest outside a hospital, but that percentage could increase significantly if bystanders recognize cardiac arrest and perform simple lifesaving tasks, a UVA Health physician says in a New England Journal of Medicine article.
Medical practitioners routinely outfit patients with devices ranging from cardiovascular stents, pacemakers, catheters, and therapeutic lenses to orthopedic, breast, dental, and cochlear implants and prostheses. In an article publishing in the SIAM Journal on Applied Mathematics, Raquel Bernardes, José Ferreira, Paula de Oliveira, Mario Grassi, and Manuel Nhangumbe present a mathematical model tha
New research from the University of Adelaide has shown that climate and economic factors are the main drivers of farmers leaving their properties in the Murray-Darling Basin, not reduced water for irrigation as commonly claimed.
Scientists have tested a new way to protect crops from a widespread and devastating bacterial disease, without using environmentally damaging chemical sprays.
A study by researchers at Woods Hole Oceanographic Institution (WHOI) shows that the microbial communities inside whales may play an important role in the digestion of one of the ocean's most abundant carbon-rich lipids, known as a wax ester. Their findings were published Dec. 2 in the Journal of the International Society for Microbial Ecology.
Scientists have tested a new way to protect crops from a widespread and devastating bacterial disease, without using environmentally damaging chemical sprays.
The Orion spacecraft with European Service Module at NASA's Plum Brook Station. The first Orion will fly farther from Earth on the Artemis I mission than any human-rated vehicle has ever flown before—but first it will undergo testing to ensure the spacecraft withstands the extremes of spaceflight.
A scientist at the Center for Astrophysics | Harvard & Smithsonian has announced the discovery that mass in triple star systems takes on the characteristics of recipient stars before mass is actually transferred, which may allow scientists to re-examine previously labeled binary star systems for evidence of a third companion.
A study by researchers at Woods Hole Oceanographic Institution (WHOI) shows that the microbial communities inside whales may play an important role in the digestion of one of the ocean's most abundant carbon-rich lipids, known as a wax ester. Their findings were published Dec. 2 in the Journal of the International Society for Microbial Ecology.
There's nothing certain in life except death and taxes. But taxpayers' support for the latter could potentially be improved, according to a new study led by SFU psychology researchers Emily Thornton and Lara Aknin.
Scientists from The Australian National University (ANU) have invented a new jelly material that mimics biological matter such as skin, ligaments and bone, and which is very strong, self-healing and able to change shape.
A new study co-authored by researchers at Queen Mary University of London has found that extreme movements in option prices are not associated with the content of news announcements per se.
Using a mathematical framework with roots in artificial intelligence and robotics, researchers have uncovered the process for how people make decisions in groups. The researchers also found they could predict a person's choice more often than more traditional descriptive methods. In large groups of essentially anonymous members, people make choices based on a model of the "mind of the group" and
If you work in medicine, does it matter if you are called by your title? Is it all right if patients, colleagues, and others call you by your first name?
A team of scientists has identified how damaged DNA molecules are repaired inside the human genome, a discovery that offers new insights into how the body works to ensure its health and how it responds to diseases that stem from impaired DNA.
A team of scientists has identified how damaged DNA molecules are repaired inside the human genome, a discovery that offers new insights into how the body works to ensure its health and how it responds to diseases that stem from impaired DNA.
PLUS. I Finansloven for 2020 er der afsat 20 mio. kr. årligt til at konvertere statens skove fra kommercielt drevet til urørt. Det er professor Carsten Rahbek glad for, men han advarer mod at klatte pengene væk på unødig administration og de forkerte skove. Minister lover 8.000 hektar urørt skov.
In her 2007 book, The Shock Doctrine , Naomi Klein coined the term disaster capitalism , which refers to the tendency of free markets and governments to respond opportunistically to catastrophic events. This phenomenon of extreme capitalism has troubling implications when it comes to climate change. As the staff writer Alexis C. Madrigal suggests, you can't buy your way out of a warming planet. I
A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman discovered. Ph.D. defence on 5 December.
How do you buy your stuff? Do you get in your car, or type with your fingers? E-commerce is surging while brick-and-mortar sales fall. What could possibly save malls and shopping centers? Enter the experience economy. In the next decade, AI-driven personalization, AR/VR interfaces, and sensor-geared smart environments could turn today's "shopping center" into a booming, invisible platform for edu
A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman discovered. Ph.D. defence on 5 December.
Brud, læsioner og kræft er de tilstande, hvor diagnosen oftest overses eller forsinkes, viser ny rapport fra Patienterstatningen og Dansk Selskab for Patientsikkerhed.
In a cleanroom in Ottobrunn, Germany, the latest Copernicus Sentinel satellite is ready for final testing before it is packed up and shipped to the US for liftoff next year. Designed and built to chart changing sea level, it is the first of two identical Sentinel-6 satellites that will be launched consecutively to continue the time series of sea-level measurements.
A new study has shown the extent to which countries drive biodiversity loss overseas through their demand for electric power. For some countries more than half of the impact on species is overseas. While the study found that the shift towards renewable electric needed to combat climate change would likely reduce the impacts on biodiversity, the overseas impact makes it difficult to understand how
Are you planning a big garden clean-up this summer, or stocking up on fly spray to keep bugs at bay? Before you do, it's worth considering the damage you might cause to the insects we share the planet with.
When cells are stressed, they initiate a complex and precisely regulated response to prevent permanent damage. One of the immediate reactions to stress signals is a reduction of protein synthesis (translation). Until now, it was difficult to measure such acute cellular changes. As reported in the latest online issue of the renowned journal Molecular Cell, researchers at Goethe University have now
Natural gas and crude oil locked away inside layers of shale, a type of sedimentary rock, is one of the nation's largest and fastest growing energy sources. According to Drew Pomerantz, a scientist at Schlumberger, an oilfield services company, two of the most fascinating scientific questions related to shales are what they are composed of and how oil and gas are stored and transported in the rock
Researchers have the first validation of a new program to assess the risk of seizures in patients with epilepsy. In a preliminary study, the Epilepsy Seizure Assessment Tool (EpiSAT) proved equally able or better than 24 specialized epilepsy clinicians at using patients' histories to identify periods of heightened propensity for seizures. " Epilepsy affects more than 3.4 million people nationwide
Registered Dietitian Melissa Mitri discusses the importance of good nutrition after giving birth and the five most important nutrients for a new mom and her baby — Read more on ScientificAmerican.com
Organisations aren't moving quickly enough on cyber security threats linked to the drive toward using personal mobile devices in the workplace, warns a QUT privacy researcher.
Pharmacists caught up in the Australian bushfire crisis are being hampered from providing timely and effective treatment to displaced people due to outdated laws, according to QUT researchers.The legal barriers pharmacists face across Australian jurisdictions include restrictive emergency medication that only covers three days as well as vaccination and relocation limitations.
It's incredibly difficult to make a carbocycle with more than five or six members. However, a research team at Tokyo University of Agriculture and Technology (TUAT) in Japan has developed a new method that can easily produce seven- and eight-membered carbocycles, which are often found in many pharmaceutical and agricultural chemicals.
Are you planning a big garden clean-up this summer, or stocking up on fly spray to keep bugs at bay? Before you do, it's worth considering the damage you might cause to the insects we share the planet with.
When cells are stressed, they initiate a complex and precisely regulated response to prevent permanent damage. One of the immediate reactions to stress signals is a reduction of protein synthesis (translation). Until now, it was difficult to measure such acute cellular changes. As reported in the latest online issue of the renowned journal Molecular Cell, researchers at Goethe University have now
Curtin University researchers have developed a promising new toolkit for monitoring threatened coral ecosystems by analyzing environmental DNA (eDNA) extracted from waters off the coast of the Cocos (Keeling) Islands.
A new study from Queen Mary University of London has found that scientists from racial and ethnic minority populations, already underrepresented in the field of science, technology, engineering and mathematics (STEM), are likely to have relatively fewer speaking opportunities at scientific conferences.
Rechargeable lithium-ion (Li-ion) batteries are a revolutionary technology, found in everything from cellphones to cars. Their ubiquity and role in breaking dependence on fossil fuels earned a trio of researchers this year's Nobel Prize in Chemistry.
New research from the University of Adelaide has shown that climate and economic factors are the main drivers of farmers leaving their properties in the Murray-Darling Basin, not reduced water for irrigation as commonly claimed.
In the first study of its kind, an IMAS-led research team estimates that around 570 000 hermit crabs have been killed on the Cocos (Keeling) Islands in the Indian Ocean and Henderson Island in the Pacific after being trapped in plastic debris.
Social capital, financial status and personal circumstances can impact engineering work placement experiences, leaving some students at a disadvantage, according to new research led by the University of Technology Sydney (UTS) with The University of Western Australia, Murdoch University and Curtin University.
Curtin University researchers have developed a promising new toolkit for monitoring threatened coral ecosystems by analyzing environmental DNA (eDNA) extracted from waters off the coast of the Cocos (Keeling) Islands.
Döttrar till kvinnor med polycystiskt ovariesyndrom (PCOS) har kraftigt ökad risk att diagnostiseras med PCOS i vuxen ålder, visar forskning från karolinska institutet. Syndromet är förknippat med en rad problem, till exempel infertilitet, psykisk ohälsa och tendens att utveckla typ 2-diabetes. Höga nivåer av manligt könshormon under graviditeten bidrar till att PCOS förs vidare till nästkommande
När backtravsplantor, som växt i mörker, får ljus börjar de bilda så kallade adventivrötter från stammen. Hur detta går till på molekylnivå, har Abdellah Lakehal studerat vid Umeå universitet. Adventivrot är en rot som utgår från en annan del av växten än själva roten. Den kan utgå från till exempel stamdelar eller bladdelar. Adventivrötter är viktiga för så kallad vegetativ (könlös) förökning ho
There is growing recognition that bringing more natural features and processes to cities could help tackle climate change, support economic growth and enhance human well-being. Nature-based solutions like green roofs and walls, sustainable urban drainage systems, natural water retention measures and urban green spaces are crucial for effectively addressing societal challenges.
Targeting a cell surface receptor essential for the function and survival of resistant prostate cancer cells can halt tumor growth, researchers report. A clinical trial is underway using a drug originally intended for lung diseases. Hormone therapies for prostate cancer have greatly prolonged the lives of patients, but the drugs eventually become ineffective and the disease grows lethal. Resistan
The important role played by the histone modification H3K27me3 in regulating gene expression in Chinese cabbage has been revealed. In addition, the collaborative research team consisting of members from Kobe University, RIKEN and CSIRO Australia, illuminated the role of H3K27me3 in vernalization.
A new study reports the first guidelines for treating sebaceous carcinoma, a cancer of the oil glands. If not removed and treated promptly, it can spread to other organs and cause grave harm to patients, including death. But up until now there was no commonly agreed method to treat it.
A Rice alumna and her statistician mentor receive the first validation of their tool to assess patients' histories to identify periods of heightened propensity for epileptic seizures.
There's nothing certain in life except death and taxes. But taxpayers' support for the latter could potentially be improved, according to a new study led by SFU psychology researchers Emily Thornton and Lara Aknin.Their work, conducted alongside University of Kansas psychologist Nyla Branscombe and University of British Columbia economist John Helliwell, reveals that when taxpayers recognize their
Doctoral student Ayasha Akter (Kobe University's Graduate School of Agricultural Science) and technical staff member Satoshi Takahashi (from the RIKEN Center for Sustainable Resource Science) have revealed the important role played by the histone modification H3K27me3 in regulating gene expression in Chinese cabbage. In addition, they illuminated the role of H3K27me3 in vernalization—a vital proce
A pair of researchers from the Observatories of the Carnegie Institution for Science and the California Institute of Technology have reported evidence that some super-puff exoplanets might be ringed exoplanets. Anthony Piro and Shreyas Vissapragada have written a paper describing their theory and the evidence supporting it and have posted it on the arXiv preprint server.
Doctoral student Ayasha Akter (Kobe University's Graduate School of Agricultural Science) and technical staff member Satoshi Takahashi (from the RIKEN Center for Sustainable Resource Science) have revealed the important role played by the histone modification H3K27me3 in regulating gene expression in Chinese cabbage. In addition, they illuminated the role of H3K27me3 in vernalization—a vital proce
Joscha Legewie, a sociologist at Harvard University has found a link between the killing of unarmed black people and an increase in local black babies being born prematurely. In his paper published in the journal Science Advances, he describes his study of birth records for black Americans living in the vicinity of killings by the police and what he found.
From domestic cats' ecocide of small animals to the greenhouse gases they emit, owning a pet is an environmental vice we must confront, writes Graham Lawton
The Mekong River has recently acquired an aquamarine color that may beguile tourists but also indicates a problem caused by upstream dams, experts in Thailand say.
Known as the Wellington Translanguaging Project, the program involves researchers from the University's School of Linguistics and Applied Language Studies—as well as Te Kawa a Māui—working with communities to collect and analyze observational data from multilingual preschools that is turned into resources to help support the successful use of translanguaging at school and at home.
Researchers at LSTM have genetically modified malaria carrying mosquitoes in order to demonstrate the role of particular genes in conferring insecticide resistance.
Perhaps fittingly for the end of the decade, 2019 was filled with thoughtful, retrospective works from master filmmakers who cast an eye on the past amid the rapid changes of the present. While veterans like Martin Scorsese and Quentin Tarantino wrestled with their moviemaking legacies, some of the other best works of the year were about the wrenching and rewarding labor that goes into a work of
Researchers at LSTM have genetically modified malaria carrying mosquitoes in order to demonstrate the role of particular genes in conferring insecticide resistance.
If you ask a child to paint a picture of the sun, you will most likely get a bright yellow circle on a piece of paper. This is actually quite accurate, given that the sun is a ball of hot gas and that its surface (called the photosphere) mostly shines in bright yellow light. The yellow color is determined by the temperature of the photosphere, which is about 5,500°C.
Research in the journal Biological Conservation, published by Elsevier, suggests fire, as it becomes more frequent and severe, poses a substantial risk to goshawks in the Sierra Nevada region.
The UPV methodology helps medical doctors know the patients' situation with greater precision; it allows them to obtain several vascular biomarkers directly linked to their survival.
When young, dark-grown seedlings of thale cress are given light, they start to form roots from the stem-like part of the plant called the hypocotyl. Abdellah Lakehal used this system to study how the initiation of these adventitious roots is regulated at the molecular level. Abdellah Lakehal successfully defended his Ph.D. thesis on Thursday, 28th of November 2019 at Umeå University.
E. coli are hardy bacteria, able to live in diverse conditions from the surface of a lettuce leaf to an acidic stomach. To survive and thrive in so many environments, the bacteria must use a network of transcriptional regulators to change their gene expression levels in response to their surroundings. Even in E. coli, one of the best characterized bacteria, it is still a significant challenge for
An international team led by the Astrophysics Department-AIM Laboratory of CEA-Irfu has just obtained new clues about the origin of star mass distribution, combining observational data from the large interferometer ALMA and the APEX radio telescope operated by the European Austral Observatory (ESO) and the Herschel Space Observatory.
The thicker the wallet, the more cooperative you are? An economist from the Max-Planck-Institute for Tax Law and Public Finance proves via laboratory experiments that rich people are believed to be more cooperative than poor people—by both the "rich" and the "poor." This aspect of conditional cooperation, which is, so far, only poorly understood, can help explain cooperation failures in socially d
When young, dark-grown seedlings of thale cress are given light, they start to form roots from the stem-like part of the plant called the hypocotyl. Abdellah Lakehal used this system to study how the initiation of these adventitious roots is regulated at the molecular level. Abdellah Lakehal successfully defended his Ph.D. thesis on Thursday, 28th of November 2019 at Umeå University.
E. coli are hardy bacteria, able to live in diverse conditions from the surface of a lettuce leaf to an acidic stomach. To survive and thrive in so many environments, the bacteria must use a network of transcriptional regulators to change their gene expression levels in response to their surroundings. Even in E. coli, one of the best characterized bacteria, it is still a significant challenge for
The Antarctic Circumpolar Current flows in a loop around Antarctica, connecting the Atlantic, Pacific and Indian oceans. It is one of the most significant ocean currents in our climate system because it facilitates the exchange of heat and other properties among the oceans it links.
David vs. Goliath Lyrics and annotation website Genius is taking Google to court. In June, Genius told The Wall Street Journal that Google had been copying music lyrics directly from its site since at least 2016, causing the site's web traffic to take a major hit. That revelation apparently wasn't enough to stop the practice, because Genius is now suing Google and its lyrics partner, LyricFind, f
It turns out we understand our planet pretty well (David Menidrey//) Climate models have come a long way. The earliest attempt to estimate what an increase in carbon dioxide could do to surface temperatures on Earth was published in 1896 . More projections began to crop up in the '60s and '70s, at a time when many scientists believed the Earth was actually cooling. But when atmospheric scientists
It has long been suggested that a cell protease could take part in enterovirus infection. However, the identities of such proteases have remained unknown. The work performed in the University of Jyväskylä shows, for the first time, that host cell calpain proteases can process enterovirus polyprotein in vitro. The research was published in Viruses in November 2019.
A study of six beaches in the coastal city of Guarujá in São Paulo state (Southeast Brazil) suggests that urbanization may be a source of stress not only for humans but also for mussels. Researchers affiliated with the Federal University of São Paulo (UNIFESP) in Santos, Brazil, and the University of New South Wales (UNSW) in Sydney, Australia, found a direct correlation among the degree of urbani
Using sophisticated screening across animal species, researchers at Yale have created a cellular blueprint of the human lung that will make it easier to understand the design principles behind lung function and disease—and to bioengineer new lungs.
It has long been suggested that a cell protease could take part in enterovirus infection. However, the identities of such proteases have remained unknown. The work performed in the University of Jyväskylä shows, for the first time, that host cell calpain proteases can process enterovirus polyprotein in vitro. The research was published in Viruses in November 2019.
Understanding how microwave absorption changes the transport properties of diffusive Josephson junctions is at the forefront of interest in the quantum transport community. It is especially relevant for current efforts to address the current-phase relation in topological Josephson junctions, and more generally, the microwave transport in quantum devices.
A study of six beaches in the coastal city of Guarujá in São Paulo state (Southeast Brazil) suggests that urbanization may be a source of stress not only for humans but also for mussels. Researchers affiliated with the Federal University of São Paulo (UNIFESP) in Santos, Brazil, and the University of New South Wales (UNSW) in Sydney, Australia, found a direct correlation among the degree of urbani
Using ESA's XMM-Newton spacecraft, astronomers have investigated the nature of a peculiar pulsar wind nebula (PWN) in the supernova remnant (SNR) CTB 87. Results of the study, presented in a paper published November 26, shed more light on the morphology and spectral properties of this object.
Using sophisticated screening across animal species, researchers at Yale have created a cellular blueprint of the human lung that will make it easier to understand the design principles behind lung function and disease—and to bioengineer new lungs.
About 2.4 billion years ago, at the end of the Archean Eon, a planet-wide increase in oxygen levels called the Great Oxidation Event (GOE) created the familiar atmosphere we all breathe today. Researchers focused on life's origins widely agree that this transition event was caused by the global proliferation of photosynthetic microbes capable of splitting water to make molecular oxygen (O2). Howev
Director Martin Scorsese was not about to ask the likes of Robert De Niro and Al Pacino to walk around his set with motion-tracking markers all over their faces.
Missing Stuff Scientists recently discovered 19 small galaxies, all of which share a puzzling quirk: they appear to be totally devoid of dark matter. Dark matter — the invisible stuff thought to hold together galaxies — is crucial to one of the leading explanations of galactic formation. But now, Live Science reports , astronomers are faced with a difficult choice: prove this new discovery wrong,
Almost 40% of global land plant species are very rare, and these species are most at risk for extinction as the climate continues to change, according to new research. "When talking about global biodiversity, we had a good approximation of the total number of land plant species, but we didn't have a real handle on how many there really are," says lead author Brian Enquist, University of Arizona p
There are picturesque but poorly studied blue lakes situated in Western Siberia. They are named so because of their color. To understand how such ecosystems function, scientists from Tyumen analyzed the chemical composition of water and studied the invertebrates' species living in them. These lakes are good model objects for studying the laws of geological history and the formation of the earth's
An under-threat flagship science project that monitors an ocean current crucial to weather on both sides of the Atlantic has been given a reprieve after funding was secured for its short-term future
NASA's Parker Solar Probe started making history the very minute it launched, taking the crown as the fastest moving launch in history. It went on to pass closer to the sun than any previous spacecraft, and now NASA has released the results of scans made during the probe's first two solar flybys. The research, published in several groundbreaking studies, offers tantalizing details on the origin o
This is a big day for clinical trial data, and unfortunately it didn't get off to a very good start. Everyone is waiting for more data on Biogen's Alzheimers program later today, but another anticipated trial has already read out. Sage Therapeutics made quite a few headlines in 2017 and 2018 when their trials of brexanalone ( allopregnanolone ) showed efficacy against post-partum depression (PPD)
Efter en blodpropp går det efter några månader att se att syrebristen i det drabbade området gett upphov till nya blodkärl. Att nybilda kärl är ett långsamt sätt för kroppen att hantera syrebrist, eller hypoxi som det heter på läkarspråk. Betydligt snabbare är att slå på en gen som bildar ett hormon kallat erytropoetin, EPO, som signalerar till benmärgen att kroppen behöver fler röda blodkroppar.
Polen på gränsen till magin Olga Tokarczuk tilldelas 2018 års Nobelpris i litteratur. Hon är en av de yngsta mottagarna under prisets historia. En "gränsöverskridande" författare står det i motiveringen, och historiska landsgränser är en av bottnarna i hennes författarskap.
– Det är ett superbra val av pristagare! Det säger Tessa Bold, forskare i nationalekonomi vid Stockholms universitet, som forskar i utvecklingsekonomi efter samma principer som pristagarna – genom så kallade fältexperiment. – Visst är det ett rätt förvånande pris, fortsätter hon. De tre forskarna är relativt unga. Men detta med utvecklingsekonomi har ju lite varit på gång, säger hon.
Upphovsmännen till litiumjonbatteriet har länge varit favorittippade till kemipriset. Få uppfinningar har fått så stort genomslag som det lätta och uppladdningsbara batteri som de utvecklade under 1970- och 1980-talen.
Abiy Ahmed blev premiärminister i Etiopien i april 2018. Han återupptog då fredssamtalen med grannlandet Eritrea. De har länge haft en relation av varken krig eller fred. Abiy Ahmed har lett normaliseringen av relationerna till Eritrea och de båda länderna undertecknade nyligen ett avtal som avslutade den 20 år långa gränskonflikten.
I sitt testamente uttryckte Alfred Nobel sin önskan att merparten av hans förmögenhet ska användas till att belöna dem som "hafva gjort menskligheten den största nytta". 1901 delades de första prisen ut. Så här lyder motiveringarna till årets pristagare
PLUS. Der er millioner at spare på at forudsige reparationer af vindmøllevinger ved hjælp af en såkaldt digital tvilling. Et fireårigt forskningsprojekt vil nu forsøge at udvikle en skabelon for alle vindmøllevinger i verden.
A new study reports high levels of patient satisfaction with a minimally invasive approach to creating vascular access for kidney patients who require hemodialysis.
The benefits of bariatric surgery for obese individuals go beyond weight loss, according to a study presented today at EuroEcho 2019, a scientific congress of the European Society of Cardiology (ESC).
A Rutgers-led team of engineers has developed an automated way to produce polymers, making it much easier to create advanced materials aimed at improving human health.
NASA's Parker Solar Probe directly samples the solar environment. (NASA/Johns Hopkins APL/Steve Gribben /) The sky is full of stars, but only one sits within our reach. Even as close as it is, the sun poses plenty of mysteries that can't be solved from Earth. Odd patterns in sunlight during solar eclipses suggest that the corona, the sun's outermost bit of atmosphere, inexplicably burns hundreds
Forestil dig en intelligent computer, der ud fra en gigantisk pulje af patientdata fra landets hospitaler kan afsløre hidtil ukendte sammenhænge om bl.a. kræft. Sådan et værktøj har professor Jens Lundgren og kolleger fra skabt med et internationalt team af IT-specialister.
Forskere ved Aarhus Universitetshospital har kastet sig ud i at undersøge, om orme i tarmen udskiller sekreter, der slår bakterier ihjel. Viser det sig at holde stik, kan ormene blive kilde til ny antibiotika, der kan redde millioner af menneskeliv.
Det er så vigtigt at vise anerkendelse for et hårdt stykke arbejde, siger hospitalsdirektør, der bruger 1,5 mio. kr. på julegaver. Et parti gummistøvler betød til gengæld forbud mod julegaver i en hel region.
Med effektiv medicinering og opsøgende indsats er det lykkedes et hold forskere ved Odense Universitetshospital at udrydde hepatitis C i Svendborg. Forskernes håb er, at strategien kan bredes ud til resten af landet.
For a little NASA spacecraft, the weather outside is frightful. The Parker Solar Probe is on a mission toward the sun. The spacecraft has been exposed to scorching temperatures and intense sunlight as it draws closer with every loop around. Eventually, Parker will glide through the star's outer atmosphere and feel the toastiness of nearly 2 million degrees Fahrenheit (more than 1 million degrees
The Christmas tree at the Tennessee aquarium is being powered by an unusual renewable energy source – an electric eel. Miguel Wattson is the resident eel and through a special system that connects his tank to a nearby tree, the natural shocks he produces when he is looking for food or when he is excited, is being channelled to power fairy lights Flashy fish: electric eel powers Tennessee aquarium
PLUS. En aktindsigt viser, at Aarhus Universitet aldrig anbefalede at sige ja til dispensere fra EU-forbuddet mod insektgiftene neonikotinoider. »Meget utilfredsstillende,« siger naturfredningsforeningen op til længe ventet rapport fra Rigsrevisionen.
Tempot i Madrid är lite högre, ibland springer deltagare verkligen mellan de fem förhandlingar som pågår parallellt, berättar klimatforskaren Mathias Fridahl vid Linköpings universitet som jämför med över 20 klimatmöten som han varit med på tidigare, sedan 2006. − Mötena ligger lite tätare och många frågor är väldigt tekniska, med en hög detaljnivå, förklarar han.
Ross Goodwin has had an extraordinary career. After playing about with computers as a child, he studied economics, then became a speech writer for President Obama, writing presidential proclamations, then took a variety of freelance writing jobs. One of these involved churning out business letters—he calls it freelance ghostwriting. The letters were all pretty much the same, so he figured out an
On a warm day in April 2013, I was sitting in a friend's kitchen in Paris, trying to engineer serendipity. I was trying to get my computer to write music on its own. I wanted to be able to turn it on and have it spit out not just any goofy little algorithmic tune but beautiful, compelling, mysterious music; something I'd be proud to have written myself. The kitchen window was open, and as I liste
I'm trying to explain to Arthur I. Miller why artworks generated by computers don't quite do it for me. There's no human being behind them. The works aren't a portal into another person's mind, where you can wander in a warren of intention, emotion, and perception, feeling life being shaped into form. What's more, it often seems, people just ain't no good, so it's transcendent to be reminded they
Hybridization, it turns out, plays a pivotal role in how life forms evolve. The tree of life may never look the same. Photograph by sezer66 / Shutterstock What is a species? It's a question that has agonized scientists since well before Darwin. With some exceptions, the thinking has landed on an evidently firm reproductive barrier: Members of different species don't mate. If they do, their offspr
A Rutgers-led team of engineers has developed an automated way to produce polymers, making it much easier to create advanced materials aimed at improving human health. The innovation is a critical step in pushing the limits for researchers who want to explore large libraries of polymers, including plastics and fibers, for chemical and biological applications such as drugs and regenerative medicine
En fast tandställning är bästa och billigaste alternativet. Mest pengar finns att spara om behandlingen görs av specialisttandläkare, enligt ny forskning. I en ny avhandling vid Malmö universitet har Ola Sollenius, övertandläkare och doktorand, undersökt kostnadseffektiviteten av behandlingar på barn med enkelsidigt korsbett. 110 barn i åldern 8-9 år lottades till fyra olika grupper där de fick b
Over de næste år kan 50.000 skoleelever lære at arbejde som en ingeniør med afsæt i virkelighedsnære, naturvidenskabelige problemer – takket være en donation på 18,7 millioner kroner fra Villum Fonden til projektet Engineering i skolen.
This animal liberation group actually wants to be put on trial. Their goal: force jurors to wear VR headsets and immerse them in the suffering of animals bound for slaughter.
When we're convinced in the truth of our ideas, we often believe if we just explain it to others that others will immediately come onboard with them. However, what we see in practice is that we need some resistance from others to help refine those ideas. In doing so, we make them more marketable in the marketplace of ideas. When we have debates, we have to not censor our opponents. We have to be
During yesterday's House Judiciary Committee hearing, the three law professors called by the Democrats and the one law professor called by the Republicans disagreed on a lot. They disagreed on what George Washington thought of executive privilege. They disagreed on what Alexander Hamilton intended by insisting that impeachment be included in the Constitution. Perhaps more to the point, they disag
Shortly after I met my wife, Cindy, in 1989—she was living in New York City at the time, while I was living in Northern Virginia—she told me about a new church she was attending in Manhattan: Redeemer Presbyterian . The young minister, she told me, was "the best pastor in America." His name was Timothy J. Keller. Since that time Keller, 69, has become one of the most consequential figures in Amer
In her eloquent impeachment testimony last month, Fiona Hill, a recently departed official at the National Security Council, criticized President Donald Trump and his supporters for parroting that Ukraine, not Russia, interfered in the 2016 elections. "This is a fictional narrative that has been perpetrated and propagated by the Russian security services themselves," Hill said on November 21. The
A Dutch university has found a former psychology researcher at the institution guilty of misconduct for several offenses, including lack of ethics approval for some of her studies and fabricating results in grant applications. In a Nov. 11, 2019, report, officials at the University of Leiden stated that the researcher, whom it does not identify, … Continue reading
We thought NASA was just monitoring space junk for the US government, but it turns out it has been selling an orbital warning service to select customers
Smart-tv'er kan blive en indgang for hackere, advarer den amerikanske sikkerhedstjeneste FBI, ligesom tv-producenter muligvis overvåger alt, hvad du ser på dit fjernsyn.
Nature Communications, Published online: 05 December 2019; doi:10.1038/s41467-019-13487-6 Chloroplasts are important for plant immunity against microbial pathogens. Here Xu et al. identify, in the wheat stripe rust fungus, a haustorium-specific protein that is translocated into chloroplasts and affects chloroplast function by interacting with a putative component of the plant cytochrome b6-f comp
Nature Communications, Published online: 05 December 2019; doi:10.1038/s41467-019-13522-6 Trypanosoma brucei relies on uptake and conversion of purines from the host, which constitutes a potential drug target. Here, Hulpia et al. combine structural elements from known trypanocidal nucleoside analogues and develop a potent trypanocide with curative activity in animal models of acute and late stage
Nature Communications, Published online: 05 December 2019; doi:10.1038/s41467-019-13501-x Many-body interactions have important consequences for the optoelectronic properties of 2D materials. Here, the authors report on how many-body interactions affect the behavior of the valley-selective optical Stark effect for excitation near the A-exciton resonance in monolayer WS2.
Nature Communications, Published online: 05 December 2019; doi:10.1038/s41467-019-13407-8 Metabotropic glutamate receptors (mGluRs) are dimeric G-protein–coupled receptors that operate at neural synapses. Here authors use FRET assays in live cells to monitor mGluR2/7's activation and reveal how heterodimerization can alter the glutamate response of an mGluR.
Nature Communications, Published online: 05 December 2019; doi:10.1038/s41467-019-13525-3 E. coli and human tRNAs contain 3-(3-amino-3-carboxypropyl)uridine (acp3U) modification. Here the authors identify E. coli TapT and human DTWD1/2 as tRNA aminocarboxypropyltransferases responsible for acp3U formation. Inhibition of acp3U modification results in genome instability in heat-stressed E. coli and
Nature Communications, Published online: 05 December 2019; doi:10.1038/s41467-019-13513-7 The authors here perform experiments to investigate the dihedral angle of olivine-H2O and olivine-H2O-NaCl systems. The observed effect of NaCl to decrease dihedral angles allows fluids to percolate through forearc mantle wedge and to accumulate in the overlying crust, accounting for the high electrical cond
Nature Communications, Published online: 05 December 2019; doi:10.1038/s41467-019-12957-1 The Paleocene-Eocene Thermal Maximum constitutes one of the largest climate perturbations in Earth's history, but its exact causes are not well known. New estimates of greenhouse gas fluxes from the North Atlantic Igneous Province at high temporal resolution show that they could have initiated this event.
Greenhouse gas emissions released directly from the movement of volcanic rocks are capable of creating massive global warming effects — a discovery which could transform the way scientists predict climate change, a new study reveals.
One of the key priorities of interventions for autism spectrum disorder (ASD) is starting early, with some evidence showing infants as young as seven months old could benefit. Yet, most children in North America aren't diagnosed with ASD until they're over four years of age. New research published in Nature Communications has found testing the DNA of siblings of individuals with ASD may be predict
A mysterious die-off of freshwater mussels has biologists scrambling to figure out a cause. Freshwater mussels are critical to river ecosystems and to U.S. water supplies.
Weary of losing neighbors and patients to gunfire, St. Louis trauma surgeon Laurie Punch has a message: Gun violence is contagious, but so is healing. Doctors who teach can be part of the solution. (Image credit: Whitney Curtis for KHN)
Greenhouse gas emissions released directly from the movement of volcanic rocks are capable of creating massive global warming effects—a discovery which could transform the way scientists predict climate change, a new study reveals.
The National Labor Relations Board claims that graduate student workers at private universities should not be considered employees. But the ruling's logic — that graduate assistants' work is primarily educational — demonstrates a fundamental misunderstanding of the duties that graduate students perform.
The burgeoning bioenergy sector must peak and decline in the next 30 years to alleviate extreme pressure on land, warns researchers in a new analysis published today in Global Change Biology. They assert that projections envisioning the use of biomass from crops, trees or grasses for fuel through 2100 overlook the technology's high carbon footprint and excessive land use.
On a cold afternoon in late November, Jan Gerrit Otterpohl eyes the chimneys of Berlin's Heizkraftwerk Mitte, a state-of-the-art power plant that supplies the city with heat and electricity. It's not the billowing steam he's interested in, but the largely invisible carbon dioxide that the power station exhales as it burns natural gas.
The computer models used to simulate what heat-trapping gases will do to global temperatures have been pretty spot-on in their predictions, a new study found.
A peer-reviewed assessment cautions that ramping up bioenergy projects requiring large stretches of land could send renewable energy sector down an unsustainable path.
New scientific projections released Wednesday predict that ocean levels will rise even faster than previously forecast over the next four decades in low-lying southeastern Florida, which is already prone to frequent flooding even on sunny days.
Historic cities and towns along the Southeastern U.S. coast have survived wars, hurricanes, disease outbreaks and other calamities, but now that sea levels are creeping up with no sign of stopping, they face a more existential crisis.
Australian bushfires have caused unprecedented pollution in Sydney and along the country's east coast, officials said Thursday, with smoke and dust burning residents' eyes and prompting a spike in respiratory complaints.
Coral reefs support 25 percent of all marine life around the globe. Those in the Gulf of Mexico, along the coasts of Louisiana, Florida, Texas and Mexico, might be less known and less popular among tourists than other reefs; nevertheless, they also serve as important barriers to storm surge, lessening the impact of dangerous hurricanes. In a new paper published in the journal Frontiers in Marine S
PLUS. Den grønne tænketank Concitos internationale chef mener, at fondens størrelse på 25 mia. kroner er markant – også set i international sammenhæng.
Det er ikke kun sine forskningsresultater som læge Cecilie Rank glæder sig til at fremvise på ASH. Hun ser også frem til networking med nationale og internationale kollegaer.
Voters have woken up to the climate emergency. Equally urgent is the threat to nature and wildlife – and the issues are linked It has been heartening to see how the climate emergency has finally risen up the political agenda in recent months. What has had much less attention, but is equally urgent, is the catastrophic decline in our nature and wildlife. The UK is one of the most nature-depleted c
On a tiny island in the Mediterranean Sea, on the fringes of the European Union, something incredible is unfolding. A political crisis and a social uprising, spurred by investigative journalism, are revealing the failures of Europe. The case is complex: Malta's best-known journalist, Daphne Caruana Galizia, was assassinated by a car bomb in October 2017. The murder has not yet been solved. A busi
Anti-vaxxers and their misinformation campaign may have killed Senate Bill 64, repealing Florida's religious exemption to childhood immunizations, which is being abused by parents. Sen. Laura Book, the bill's sponsor, remains undeterred, citing the high risk of disease outbreaks in Florida.
Att inte längre vara någon att räkna med, att vara begränsad och hamna i beroende på grund av kroppens skröplighet eller att behöva ta hand om svåra situationer själv utan att kunna dela upplevelsen med någon annan. Så beskriver några sköra äldre personer vad existentiell ensamhet kan betyda för dem.
University of Missouri School of Medicine researchers have found a potential cause for elevated nighttime blood pressure that may help patients with OSA get the help they need before cardiovascular disease develops.
A new IZA World of Labor report publishing tomorrow, Dec. 5, 2019, finds teacher effectiveness to have a strong effect on pupils attainment. It goes on to look at ways to increase it including reforming hiring practices, and reforming teacher training and development.
A new study finds more than two-fold differences between counties with the lowest and highest rates of surgery for patients with early stage lung cancer, with socioeconomic and healthcare delivery factors contributing to the gap.
PLUS. I 2010 blev det lov, at der ikke må være mere end 100 Bq/m3 radon i indeluften i nye huse. Men 11 procent af husene i en ny undersøgelse ligger over det niveau.
We show that rotating particles at the liquid–gas interface can be efficiently manipulated using the surface-wave analogue of optical lattices. Two orthogonal standing waves generate surface flows of counter-rotating half-wavelength unit cells, the liquid interface metamaterial, whose geometry is controlled by the wave phase shift. Here we demonstrate that by…
Nonribosomal peptide synthetases (NRPSs) generate the core peptide scaffolds of many natural products. These include small cyclic dipeptides such as the insect feeding deterrent peramine, which is a pyrrolopyrazine (PPZ) produced by grass-endophytic Epichloë fungi. Biosynthesis of peramine is catalyzed by the 2-module NRPS, PpzA-1, which has a C-terminal reductase…
Resistance in Anopheles gambiae to members of all 4 major classes (pyrethroids, carbamates, organochlorines, and organophosphates) of public health insecticides limits effective control of malaria transmission in Africa. Increase in expression of detoxifying enzymes has been associated with insecticide resistance, but their direct functional validation in An. gambiae is still…
Recent progress in understanding the electronic band topology and emergent topological properties encourage us to reconsider the band structure of well-known materials including elemental substances. Controlling such a band topology by external field is of particular interest from both fundamental and technological viewpoints. Here we report possible signatures of the…
Hydrocarbon films confined between smooth mica surfaces have long provided an experimental playground for model studies of structure and dynamics of confined liquids. However, fundamental questions regarding the phase behavior and shear properties in this simple system remain unsolved. With ultrasensitive resolution in film thickness and shear stress, and control…
Understanding the stability of ecological communities is a matter of increasing importance in the context of global environmental change. Yet it has proved to be a challenging task. Different metrics are used to assess the stability of ecological systems, and the choice of one metric over another may result in…
How changes in enzyme structure and dynamics facilitate passage along the reaction coordinate is a fundamental unanswered question. Here, we use time-resolved mix-and-inject serial crystallography (MISC) at an X-ray free electron laser (XFEL), ambient-temperature X-ray crystallography, computer simulations, and enzyme kinetics to characterize how covalent catalysis modulates isocyanide hydratase (
Flavodoxins, electron transfer proteins essential for diverse metabolisms in microbes from the domain Bacteria, are extensively characterized. Remarkably, although genomic annotations of flavodoxins are widespread in microbes from the domain Archaea, none have been isolated and characterized. Herein is described the structural, biochemical, and physiological characterization of an unusual flavodox
Fungi are ubiquitous and often abundant components of virtually all ecosystems on Earth, serving a diversity of functions. While there is clear evidence that fungal-mediated processes can influence environmental conditions, and in turn select for specific fungi, it is less clear how fungi respond to environmental fluxes over relatively long…
Changes in heart rate, due to low oxygen conditions, experienced by the fetus during pregnancy, could be used to predict the future heart health of babies, shows research published in The Journal of Physiology today.
A study done in South America found that with increasing population density humans had more diversity of fungi on the skin but less microbial diversity in the gut.
Tegn abonnement på
BioNyt Videnskabens Verden (www.bionyt.dk) er Danmarks ældste populærvidenskabelige tidsskrift for naturvidenskab. Det er det eneste blad af sin art i Danmark, som er helliget international forskning inden for livsvidenskaberne.
Bladet bringer aktuelle, spændende forskningsnyheder inden for biologi, medicin og andre naturvidenskabelige områder som f.eks. klimaændringer, nanoteknologi, partikelfysik, astronomi, seksualitet, biologiske våben, ecstasy, evolutionsbiologi, kloning, fedme, søvnforskning, muligheden for liv på mars, influenzaepidemier, livets opståen osv.
Artiklerne roses for at gøre vanskeligt stof forståeligt, uden at den videnskabelige holdbarhed tabes.
Tegn abonnement på
BioNyt Videnskabens Verden (www.bionyt.dk) er Danmarks ældste populærvidenskabelige tidsskrift for naturvidenskab. Det er det eneste blad af sin art i Danmark, som er helliget international forskning inden for livsvidenskaberne.
Bladet bringer aktuelle, spændende forskningsnyheder inden for biologi, medicin og andre naturvidenskabelige områder som f.eks. klimaændringer, nanoteknologi, partikelfysik, astronomi, seksualitet, biologiske våben, ecstasy, evolutionsbiologi, kloning, fedme, søvnforskning, muligheden for liv på mars, influenzaepidemier, livets opståen osv.
Artiklerne roses for at gøre vanskeligt stof forståeligt, uden at den videnskabelige holdbarhed tabes.
Share this ArticleLike this article? Email it to a friend!
Recent Comments