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nyheder2019februar13

Why too much DNA repair can injure tissue

Researchers have discovered how overactive DNA repair systems can lead to retinal damage and blindness in mice. A DNA repair enzyme called Aag glycosylase becomes hyperactive, provoking an inflammatory response that produces necrosis, leading to severe tissue damage.

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FDA Cracks Down on "Bad Actors" in Dietary Supplement Market

The agency sends warning letters to makers of products that claim to prevent or treat Alzheimer's and other diseases, and announces changes to its enforcement practices.

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It Turns Out You Can Learn Things While You’re Asleep

All-Nighter It turns out all of those people who tried to learn a new language or quit smoking by listening to recordings while they slept may have been on to something. Under the right conditions, it turns out, the sleeping human brain is capable of learning new vocabulary. That’s according to a study by scientists from Switzerland’s University of Bern, published in the journal Current Biology i

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New "swallowable needles" could deliver insulin as a pill

Insulin breaks down in the stomach, so diabetics haven't had the option of taking insulin in a pill. A new device whose design is inspired by tortoises can be swallowed and inject diabetics with insulin from the inside. Though it's still a prototype, the device is an exciting development for delivering insulin and other drugs. None No matter the delivery mechanism, consistently getting a dose of

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California nixes plans for high-speed LA-SF rail line

California Governor Gavin Newsom announced on Tuesday that he was abandoning plans to build a high-speed rail line between Los Angeles and San Francisco, citing the high cost and the time it would take.

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Texas A&M-led study explores the role of estrogen in controlling Type 2 diabetes

The results of a recent Texas A&M University-led study provide insights into the mechanism by which estrogen can decrease insulin resistance and the production of glucose, reducing incidences of Type 2 diabetes mellitus.

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Indonesia's devastating 2018 earthquake was a rare supershear, UCLA study finds

The devastating 7.5 magnitude earthquake that struck the Indonesian island of Sulawesi last September was a rare 'supershear' earthquake, according to a study led by UCLA researchers. Only a dozen supershear quakes have been identified in the past two decades.

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Infosys forms community college partnership in Rhode Island

Technology company Infosys announced a new partnership with a community college in Rhode Island to develop workers for digital jobs on Tuesday, with the goal of forming similar arrangements elsewhere in the country.

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This startup wants its fusion reactor to actually produce power

submitted by /u/tachyonburst [link] [comments]

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Measles cases have tripled in Europe, fueled by Ukrainian outbreak

With more than 54,000 cases in 1 year, Ukraine tries to encourage vaccination

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Polar bears invade Russian town; locals delighted but wary

Russian wildlife specialists are heading for an Arctic archipelago to try to resolve a situation that has both terrified and delighted the locals: the polar bears that moved into a populated area.

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Aqua satellite catches development of Tropical Cyclone Oma

NASA's Aqua satellite passed over the Southern Pacific Ocean and captured a visible image of Tropical Cyclone Oma. Oma formed northwest of Vanuatu.

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Moving artificial leaves out of the lab and into the air

Artificial leaves mimic photosynthesis—the process whereby plants use water and carbon dioxide from the air to produce carbohydrates using energy from the sun. But even state-of-the-art artificial leaves, which hold promise in reducing carbon dioxide from the atmosphere, only work in the laboratory because they use pure, pressurized carbon dioxide from tanks.

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Salt Doesn't Melt Ice—Here's How It Makes Winter Streets Safer

There’s a good reason to salt the roads before snow starts falling — Read more on ScientificAmerican.com

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Polar bears invade Russian town; locals delighted but wary

Russian wildlife specialists are heading for an Arctic archipelago to try to resolve a situation that has both terrified and delighted the locals: the polar bears that moved into a populated area.

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Women scarce in the one percent: Glass ceiling is more extensive than previously thought, study shows

Men hold nearly all primary breadwinning positions in top income households, and the glass ceiling that has hindered women's advancement in the workplace is more extensive than previously thought, a new study by University of North Carolina at Charlotte researcher Jill Yavorsky and colleagues finds.

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Laser-induced graphene gets tough, with help

Laser-induced graphene (LIG), a flaky foam of the atom-thick carbon, has many interesting properties on its own but gains new powers as part of a composite.

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ORNL teams with Los Alamos, EPB to demonstrate next-generation grid security tech

A team of researchers from the Department of Energy's Oak Ridge and Los Alamos National Laboratories has partnered with EPB, a Chattanooga utility and telecommunications company, to demonstrate the effectiveness of metro-scale quantum key distribution (QKD) as a means of secure communication for the nation's electricity suppliers. This initial milestone is part of the team's three-year project foc

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Walter Munk, “Einstein of the Oceans” Dies

The marine scientist was renowned for his passion for exploring waves, marine life, and the way Earth’s largest bodies of water affect the planet’s climate.

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Gorgeous Fractal Patterns, Normally Found Only in Nature, Re-Created Using Laser Light

A human-made thing created a very beautiful, natural pattern.

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NASA-NOAA satellite finds Tropical Cyclone Gelena sheared

Wind shear can push tropical cyclones apart and satellite imagery from NASA-NOAA's Suomi NPP satellite revealed that is what is happening to Tropical Cyclone Gelena in the Southern Indian Ocean.

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Laser-induced graphene gets tough, with help

Laser-induced graphene created at Rice University combines with many materials to make tough, conductive composites for wearable electronics, anti-icing, antimicrobial applications, sensors and water treatment.

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Moving artificial leaves out of the lab and into the air

Researchers from the University of Illinois at Chicago have proposed a design solution that could bring artificial leaves out of the lab and into the environment. Their improved leaf, which would use carbon dioxide — a potent greenhouse gas — from the air, would be at least 10 times more efficient than natural leaves at converting carbon dioxide to fuel.

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Slower runners benefit most from elite methods

How much do high-tech shoes, special diets and exercises, drafting behind other runners and other strategies to improve your 'running economy' actually improve your finish time? A new study spells it out. The takeaway: The faster you are, the harder it is to get faster.

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NASA's Aqua Satellite catches development of Tropical Cyclone Oma

NASA's Aqua satellite passed over the Southern Pacific Ocean and captured a visible image of Tropical Cyclone Oma. Oma formed northwest of Vanuatu.

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How doctors can help low-income patients (and still make a profit) | P.J. Parmar

Modern American health care is defined by its high costs, high overhead and inaccessibility — especially for low-income patients. What if we could redesign the system to serve the poor and still have doctors make money? In an eye-opening (and surprisingly funny) talk, physician P.J. Parmar shares the story of the clinic he founded in Colorado, where he serves only resettled refugees who mostly us

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Europe's Next Big-Budget Science Projects: 6 Teams Proceed to Final Round

AI enhancement and a virtual time machine are included in the short list of pitches — Read more on ScientificAmerican.com

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Norgen Biotek's Cell-free DNA / Cell-free RNA (cf-DNA/cf-RNA) BCT Tube is Best-In-Class

Norgen Biotek Corp., an innovative privately held Canadian biotechnology company focusing primarily on advancing powerful tools for nucleic acid and protein stabilization and purification, today announced their unique cf-DNA/cf-RNA Preservative Tubes were found to be the most suitable for liquid biopsy when compared to other leading competitor's blood collection tubes (BCTs)

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Here's how global warming will change your town's weather by 2080

Environment A clever study finds modern analogs for what our cities will feel like in 2080. You may have morbidly joked that you’ll have to move north to escape the impending wave of climate change, but you'll have to go further than you think.

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What’s the Buzz? Mosquitoes Can Hear You From 30 Feet Away

If a tree drops in the forest and no one is around to hear it, does it make a sound? Humans may never know, but mosquitoes might. Until now, it was thought that mosquitoes could only hear a few inches away, but new research shows that they can detect sound from up to 32 feet away. This surprising ability allows Aedes aegypti mosquitos to track down distant mates and even tune in to human speech. T

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The Green New Deal Is Just the Vague, Audacious Goal We Need

The Green New Deal unveiled by congressional Democrats last week is fairly criticized for being vague and unrealistic. But the US needs ambitious societal goals.

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Alan Watts was overzealous in his basic income prediction – but he wasn't wrong

Economist Robert Theobald coined the team 'basic living guarantee' in the 1960s. He believed that we were going to suffer problems because of an overabundance of resources. Philosopher Alan Watts spoke about the possibility of an economic utopia through a universal basic income. The perceived threat of labor-ending automation, a stratified elite class, and increasingly complex occupations have le

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Testosterone limits for female athletes based on 'flawed' research

New rules governing international track and field competitions would require some women to medically reduce their testosterone levels to compete. A new study suggests the regulations are rooted in flawed science.

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Large study fails to link phthalates and increased breast cancer risk

In the largest study to date on phthalates and postmenopausal breast cancer, a University of Massachusetts Amherst cancer epidemiology researcher found no association between breast cancer risk and exposure to the plasticizing and solvent chemicals used in such common products as shampoo, makeup, vinyl flooring, toys, medical devices and car interiors.

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NASA Astronaut Runs for Senate, Warns Of “Retreat From Science”

Space Candidate Former NASA astronaut Mark Kelly announced Tuesday that he’s running for Senate in Arizona — and he’s positioning himself as a defender of science during an era when it’s under threat. “We’ve seen this retreat from science and data and facts, and if we don’t take these issues seriously, we can’t solve these problems,” Kelly said in an announcement video . “We’re going to need to b

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Watch an Ice Skating Robot Play Hockey

He Was a Skaterbot It’s a skill not even every human possesses: skating on ice. But a Swiss robot dubbed “Skaterbot” managed to learn . The maverick quadruped belongs to Stelian Coros, a professor at ETH Zurich’s Computational Robotics Lab. Skaterbot was shown off at a local ice skating rink during last month’s World Ecosnomic Forum in Davos, Switzerland. An official video shows Skaterbot competi

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A new 2-D material uses light to quickly and safely purify water

A newly designed material uses only light to speedily remove 99.9999 percent of microbes from water.

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NASA-NOAA satellite finds Tropical Cyclone Gelena sheared

Wind shear can push tropical cyclones apart and satellite imagery from NASA-NOAA's Suomi NPP satellite revealed that is what is happening to Tropical Cyclone Gelena in the Southern Indian Ocean.

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Women scarce in the one percent

Looking at income inequality reveals vast gender inequality as well, according to a new study. While the families earning in the top one percent of American household incomes receive nearly one-fourth of all U.S. income, the bulk of earning is done by men. Women's income alone is sufficient for one percent status in only five percent of elite households. Moreover, women's income contributes to ach

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New machine learning method could spare some women from unnecessary breast surgery

Dartmouth researchers have developed and evaluated a machine learning approach of using patient core needle biopsy data to identify the risk that atypical ductal hyperplasia (ADH) breast lesions may upgrade to cancer. This knowledge can potentially help clinicians and low-risk patients decide whether active surveillance and hormonal therapy is a reasonable management approach. Using the method cou

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Bird flu shuffle probes viral compatibility

Emory scientists have been probing the RNA packaging factors that limit reassortment between avian H7N9/H5N8 strains and a well-known strain (H3N2) that has been dominating the last few human flu seasons in the United States. Mix and match still occurred at a low level, particularly with H5N8.

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Huge Meteor Left Crater Hidden Beneath Greenland Ice

Scientists have discovered the second-ever meteor impact crater in Greenland, located not far from the first.

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Slow-going restoration at fire-gutted Brazilian museum

Five months after a devastating fire engulfed Brazil's National Museum, the facility is still in dire straits and efforts to rebuild slow-moving.

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Charles Darwin wrote enough one-liners to fill a burn book

Science Here are the saddest, meanest, funniest Darwin quotes. Between experiments and excursions, Charles Darwin was a prolific author of scalding one-liners.

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Insulating crust kept cryomagma liquid for millions of years on nearby dwarf planet

A recent NASA mission to the dwarf planet Ceres found brilliant, white spots of salts on its surface. New research led by The University of Texas at Austin in partnership with NASA's Jet Propulsion Laboratory (JPL) delved into the factors that influenced the volcanic activity that formed the distinctive spots and that could play a key role in mixing the ingredients for life on other worlds.

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Researchers discover new frog species on remote Ethiopian mountain

In summer 2018, NYU Abu Dhabi Postdoctoral Associates Sandra Goutte and Jacobo Reyes-Velasco explored an isolated mountain in southwestern Ethiopia where some of the last primary forest of the country remains. Bibita Mountain was under the radars of the team for several years due to its isolation and because no other zoologist had ever explored it before.

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Amid border wall debate, 'smart' tech raises questions too

As congressional Democrats counter President Donald Trump's border wall plan with a high-tech solution, the idea of a "smart" security barrier is raising fresh questions over the potential for intrusive surveillance.

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Researchers discover new frog species on remote Ethiopian mountain

In summer 2018, NYU Abu Dhabi Postdoctoral Associates Sandra Goutte and Jacobo Reyes-Velasco explored an isolated mountain in southwestern Ethiopia where some of the last primary forest of the country remains. Bibita Mountain was under the radars of the team for several years due to its isolation and because no other zoologist had ever explored it before.

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Pandekage, kegle eller snemand? Rumsonde sender nye billeder af fjernt objekt

Nye billeder afslører, at rumobjektet Ultima Thule, der er blevet beskrevet som en kæmpe snemand, er fladere end forventet.

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High-flying pseudosatellites get their day in the sun

High-flying pseudosatellites get their day in the sun High-flying pseudosatellites get their day in the sun, Published online: 12 February 2019; doi:10.1038/d41586-019-00561-8 Planes and airships that can soar through the stratosphere could enable new approaches to research.

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Mars One died before it could become Fyre Festival: Space Edition

Space You've likely outlived the company that wanted to film you dying on Mars. Mars One, a controversial startup with the singular goal of sending humans on a one-way trip to the red planet, is finally (and unsurprisingly) kaputt.

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NASA Spots Another Possible Impact Crater Buried Under Greenland Ice

The newfound crater candidate is thought to be unrelated to another that was discovered last year — Read more on ScientificAmerican.com

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Insulating crust kept cryomagma liquid for millions of years on nearby dwarf planet

A recent NASA mission to the dwarf planet Ceres found brilliant, white spots of salts on its surface. New research delved into the factors that influenced the volcanic activity that formed the distinctive spots and that could play a key role in mixing the ingredients for life on other worlds.

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Laser physics: Transformation through light

Laser physicists have taken snapshots of how C60 carbon molecules react to extremely short pulses of intense infrared light.

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Infection biology: What makes Helicobacter so adaptable?

The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. Microbiologists have identified an enzyme that plays a vital role in the flexible control of global gene expression in the species.

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Insulating crust kept cryomagma liquid for millions of years on nearby dwarf planet

A recent NASA mission to the dwarf planet Ceres found brilliant, white spots of salts on its surface. New research led by The University of Texas at Austin in partnership with NASA's Jet Propulsion Laboratory (JPL) delved into the factors that influenced the volcanic activity that formed the distinctive spots and that could play a key role in mixing the ingredients for life on other worlds.

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Hackers Can Access Your Electric Scooter While You’re Riding It

Remote Control If you see people on electric scooters wildly accelerating and braking, it might not only be because of the usual electric scooter nonsense . That’s because a newly-discovered security flaw in a particular scooter’s software can be exploited by hackers who can remotely accelerate or brake someone else’s scooter, according to WIRED . It’s a finding that highlights the fraught landsc

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Possibility of recent underground volcanism on Mars

New research suggests liquid water is present beneath the south polar ice cap of Mars. Now, a new study argues there needs to be an underground source of heat for liquid water to exist underneath the polar ice cap.

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Disney's Building Its Own Streamer—Why Take Shows to Hulu?

There's a reason Howard the Duck is going to Hulu and not Disney+.

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Photos From the 2019 Westminster Dog Show

This year’s 143rd annual Westminster Kennel Club Dog Show is hosting 2,800 dogs, consisting of more than 200 different breeds or varieties. Below are images from the two-day competition and preliminary activities held in New York City at Piers 92/94 and Madison Square Garden. And, for a closer look at the road to Westminster and the life of a show-dog breeder, please read “ Backstage at the Westm

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No One Really Knows What to Do With All of America’s Unclaimed Corpses

Sarah Krebs is used to corpses going missing. As a detective who works in the missing-persons unit in Detroit, she has solved dozens of cases by matching up disappeared people to unidentified bodies left in state custody. But for older cases in which the county was supposed to have buried the body, Krebs says it’s common for her to order an exhumation from the local cemetery and discover that the

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Teaching self-driving cars to predict pedestrian movement

By zeroing in on humans' gait, body symmetry and foot placement, researchers are teaching self-driving cars to recognize and predict pedestrian movements with greater precision than current technologies.

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Why too much DNA repair can injure tissue

MIT researchers have discovered how overactive DNA repair systems can lead to retinal damage and blindness in mice. A DNA repair enzyme called Aag glycosylase becomes hyperactive, provoking an inflammatory response that produces necrosis, leading to severe tissue damage.

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NYU Abu Dhabi researchers discover new frog species on remote Ethiopian mountain

A new species of puddle frog (order: Anura, family: Phynobatrachidae, genus: Phrynobatrachus), has just been discovered by NYU Abu Dhabi researchers at the unexplored and isolated Bibita Mountain in southwestern Ethiopia. The research team named the new species Phrynobatrachus bibita sp. nov., or Bibita Mountain dwarf puddle frog, inspired by its home.

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Musical surprises light up the brain’s reward center

Surprises in music activate the reward center of our brains, and help us learn about the music as we listen, research finds. Researchers put 20 volunteers through a musical reward learning task. Each participant chose a color, then a direction. Each choice came with a certain probability of leading to either a consonant, pleasurable musical excerpt or a dissonant, unpleasant one. Over time, the s

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Paul Jr. Designs a Bike for MLB Network | American Chopper

Paul Jr. challenges himself to build a streamlined bike for the MLB Network to impress his dad. Stream Full Episodes of American Chopper: https://www.discovery.com/tv-shows/american-chopper/ Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Join us on Facebook: https://www.facebook.com/Discovery Follow us on Twitter: https://twitter.com/Discovery We're on Instagram! https://www.instagram.c

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Green New Deal : Can this plan pushed by some Democrats really work?

A radical plan to tackle climate change pushed by Alexandria Ocasio-Cortez may now come to the Senate for a vote.

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How Many Creationists Are There in America?

A new survey shows the number can vary considerably depending how you ask questions about evolution — Read more on ScientificAmerican.com

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With age comes hearing loss and a greater risk of cognitive decline

In a new study, researchers report that hearing impairment is associated with accelerated cognitive decline with age, though the impact of mild hearing loss may be lessened by higher education.

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More efficient system to reprogram stem cells

Induced pluripotent stem cells, the workhorse of many regenerative medicine projects, start out as differentiated cells that are reprogrammed to pluripotent stem cells by exposure to a complex set of genetic cocktails.

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Climate of North American cities will shift hundreds of miles in one generation

In one generation, the climate experienced in many North American cities is projected to change to that of locations hundreds of miles away — or to a new climate unlike any found in North America today. A new study and interactive web application aim to help the public understand how climate change will impact the lives of people who live in urban areas of the United States and Canada. These new

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Once seen as nerve cells' foot soldier, the axon emerges as decision-maker

New research reveals that parts of the neuron are far more complex than once thought.

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Elon Musk: Moving to Mars will cost less than $500,000, 'maybe even below $100,000

submitted by /u/BirdIsTheWorldTruly [link] [comments]

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Last week in tech: Apex Legends, America's AI Initiative, and a long-awaited Gmail feature

Technology It's OK to be bad at the super-popular new video game. Check out our new podcast!

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New AI toolkit is the 'scientist that never sleeps'

Researchers have developed a new AI-driven platform that can analyze how pathogens infect our cells with the precision of a trained biologist.

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Wreckage Of WWII Aircraft Carrier Found In The South Pacific Ocean

The Hornet played a role in several key events in the war – including the Doolittle Raid on Japan and the Battle of Midway. Researchers have located it 3 miles below the surface. (Image credit: Photo courtesy of Paul G. Allen's Vulcan Inc)

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To see the value of love, look to animals

For Valentine’s Day, a biologist explains animals in love and what they can teach us. Humans just love seeing animals demonstrate love: cuddly chimps grooming each other, say, or penguin pairs carefully passing their egg in the driving snow. Viral videos of cows joining dog packs or cats and birds becoming friends dot our social media feeds. “There are lots of biological explanations for these ki

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Walmart's same-day grocery delivery hits another snag

Walmart's same-day grocery delivery service has hit a snag. The giant retailer had partnered with Google-backed logistics company Deliv to get orders to customers' front doors, …

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How Many Creationists Are There in America?

A new survey shows the number can vary considerably depending how you ask questions about evolution — Read more on ScientificAmerican.com

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New dinosaur relative was ‘king’ of Antarctica

Researchers have discovered a new dinosaur species, an iguana-sized reptile whose genus name, Antarctanax , means “Antarctic king.” Antarctica wasn’t always a frozen wasteland. About 250 million years ago, it was covered in forests and rivers, and the temperature rarely dipped below freezing. It was also home to diverse wildlife, including early relatives of the dinosaurs. “This new animal was an

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Hyperactive kindergarten boys may earn less later

Boys from low-income backgrounds who are hyperactive and inattentive in kindergarten earn less money as long as 30 years later, a new study shows. Disruptive behaviors in childhood, among the most prevalent and costly mental health problems in industrialized countries, link to significant negative long-term outcomes for individuals and society, researchers say. Recent evidence suggests that disru

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The Trials of Creating Vegan, Kosher, Halal, Meat-Free Gelatin

submitted by /u/jsb523 [link] [comments]

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Pentagon Warns That Enemies Could Shoot US Satellites With Lasers

Battle Ready For the past year, the U.S. has been throwing around the idea of establishing a “ Space Force ” to prepare it for off-world warfare. On Monday, the public got a clearer idea of just what kind of battles the nation expects might be on the horizon: satellite attacks by laser weapons. In other words, the real world is sounding more like “Star Wars” every day. Major Lasers On Monday, the

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China and India help make planet leafier

There are now more than 2 million sq miles of extra leaf area per year, compared with the early 2000s.

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What happens when you take a genealogy test

Two BBC journalists succumbed to the trend and took at-home genealogy tests. This is what they found.

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Why polar bears are invading human settlements

Why is a part of Russia in a state of emergency over polar bears?

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Spectacular Fossil Bird Foot Preserved in Amber

A rare amber inclusion underscores the importance of carnivores to the fossil record — Read more on ScientificAmerican.com

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Zinc depletion does not necessarily induce ribosome hibernation in mycobacteria [Biological Sciences]

In PNAS, Li et al. (1) recently reported analysis of Mycobacterium smegmatis ribosomes formed under zinc-limited conditions. A zinc chelator [N,N,N′,N′-tetrakis(2-pyridylmethyl)-ethylenediamine] was added to growth medium and an extended purification procedure was employed to obtain zinc-depleted (C−) ribosomes for cryo-EM. The structure was solved at 3.5-Å resolution and showed five…

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Reply to Tobiasson et al.: Zinc depletion is a specific signal for induction of ribosome hibernation in mycobacteria [Biological Sciences]

We previously reported (1) in PNAS that zinc depletion in Mycobacterium smegmatis leads to reprogramming of ribosomes in which five ribosomal proteins (r-proteins) with a conserved zinc-finger CXXC motif (C+) are replaced by their paralogs lacking the motif (C−). Notably, the reprogrammed ribosomes enter into a hibernating state by binding…

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Quantum dots crack the influenza uncoating puzzle [Biophysics and Computational Biology]

One hundred years ago, the devastating 1918–1919 Spanish influenza pandemic took the lives of 50 to 100 million people, or 3 to 5% of the world population (1). Influenza A virus (IAV) pandemics occur when an animal IAV crosses the species barrier, usually by acquiring a new genetic trait by…

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Species coexistence through competition and rapid evolution [Ecology]

With nature “red in tooth and claw” (1), how do so many species coexist? Why do some species not outcompete the others to extinction? This is a question that has long fascinated ecologists and evolutionary biologists (2), especially given the incredible diversity of seemingly similar species in tropical forests or…

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Biodiversity conservation of Morlocks in west-central Texas [Evolution]

In PNAS, Devitt et al. (1) present a profoundly interesting and important report of phylogeographic and phylogenetic analyses of a group of salamanders in the genus Eurycea in the Edwards and Trinity aquifers in west-central Texas. These analyses led the authors to extend the scope of their study to analyze…

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Magnetic control of graphitic microparticles in aqueous solutions [Applied Physical Sciences]

Graphite is an inexpensive material with useful electrical, magnetic, thermal, and optical properties. It is also biocompatible and used universally as a substrate. Micrometer-sized graphitic particles in solution are therefore ideal candidates for novel lab-on-a-chip and remote manipulation applications in biomedicine, biophysics, chemistry, and condensed-matter physics. However, submerged graphi

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SNARE machinery is optimized for ultrafast fusion [Biophysics and Computational Biology]

SNARE proteins zipper to form complexes (SNAREpins) that power vesicle fusion with target membranes in a variety of biological processes. A single SNAREpin takes about 1 s to fuse two bilayers, yet a handful can ensure release of neurotransmitters from synaptic vesicles much faster: in a 10th of a millisecond….

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Exploring fast proton transfer events associated with lateral proton diffusion on the surface of membranes [Chemistry]

Proton diffusion (PD) across biological membranes is a fundamental process in many biological systems, and much experimental and theoretical effort has been employed for deciphering it. Here, we report on a spectroscopic probe, which can be tightly tethered to the membrane, for following fast (nanosecond) proton transfer events on the…

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Dynamics of frequency-swept nuclear spin optical pumping in powdered diamond at low magnetic fields [Physics]

A broad effort is underway to improve the sensitivity of NMR through the use of dynamic nuclear polarization. Nitrogen vacancy (NV) centers in diamond offer an appealing platform because these paramagnetic defects can be optically polarized efficiently at room temperature. However, work thus far has been mainly limited to single…

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Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction [Biochemistry]

Since the late 1980s, mutations in the RAS genes have been recognized as major oncogenes with a high occurrence rate in human cancers. Such mutations reduce the ability of the small GTPase RAS to hydrolyze GTP, keeping this molecular switch in a constitutively active GTP-bound form that drives, unchecked, oncogenic…

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Fanconi anemia protein FANCI functions in ribosome biogenesis [Biochemistry]

Fanconi anemia (FA) is a disease of DNA repair characterized by bone marrow failure and a reduced ability to remove DNA interstrand cross-links. Here, we provide evidence that the FA protein FANCI also functions in ribosome biogenesis, the process of making ribosomes that initiates in the nucleolus. We show that…

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Torsional stress generated by ADF/cofilin on cross-linked actin filaments boosts their severing [Biophysics and Computational Biology]

Proteins of the actin depolymerizing factor (ADF)/cofilin family are the central regulators of actin filament disassembly. A key function of ADF/cofilin is to sever actin filaments. However, how it does so in a physiological context, where filaments are interconnected and under mechanical stress, remains unclear. Here, we monitor and quantify…

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Cells exhibiting strong p16INK4a promoter activation in vivo display features of senescence [Cell Biology]

The activation of cellular senescence throughout the lifespan promotes tumor suppression, whereas the persistence of senescent cells contributes to aspects of aging. This theory has been limited, however, by an inability to identify and isolate individual senescent cells within an intact organism. Toward that end, we generated a murine reporter…

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Species delimitation in endangered groundwater salamanders: Implications for aquifer management and biodiversity conservation [Evolution]

Groundwater-dependent species are among the least-known components of global biodiversity, as well as some of the most vulnerable because of rapid groundwater depletion at regional and global scales. The karstic Edwards–Trinity aquifer system of west-central Texas is one of the most species-rich groundwater systems in the world, represented by dozens…

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Mutual interplay between IL-17-producing {gamma}{delta}T cells and microbiota orchestrates oral mucosal homeostasis [Immunology and Inflammation]

γδT cells are a major component of epithelial tissues and play a role in tissue homeostasis and host defense. γδT cells also reside in the gingiva, an oral tissue covered with specialized epithelium that continuously monitors the challenging dental biofilm. Whereas most research on intraepithelial γδT cells focuses on the…

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Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies [Medical Sciences]

Cooption of the host vasculature is a strategy that some cancers use to sustain tumor progression without—or before—angiogenesis or in response to antiangiogenic therapy. Facilitated by certain growth factors, cooption can mediate tumor infiltration and confer resistance to antiangiogenic drugs. Unfortunately, this mode of tumor progression is difficult to target…

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Ferroptosis as a target for protection against cardiomyopathy [Medical Sciences]

Heart disease is the leading cause of death worldwide. A key pathogenic factor in the development of lethal heart failure is loss of terminally differentiated cardiomyocytes. However, mechanisms of cardiomyocyte death remain unclear. Here, we discovered and demonstrated that ferroptosis, a programmed iron-dependent cell death, as a mechanism in murine…

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Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A [Microbiology]

Human betacoronaviruses OC43 and HKU1 are endemic respiratory pathogens and, while related, originated from independent zoonotic introductions. OC43 is in fact a host-range variant of the species Betacoronavirus-1, and more closely related to bovine coronavirus (BCoV)—its presumptive ancestor—and porcine hemagglutinating encephalomyelitis virus (PHEV). The β1-coronaviruses (β1CoVs) and HKU1 employ

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Agent-based representations of objects and actions in the monkey pre-supplementary motor area [Neuroscience]

Information about objects around us is essential for planning actions and for predicting those of others. Here, we studied pre-supplementary motor area F6 neurons with a task in which monkeys viewed and grasped (or refrained from grasping) objects, and then observed a human doing the same task. We found “action-related…

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Developmental trajectory of social influence integration into perceptual decisions in children [Neuroscience]

The opinions of others have a profound influence on decision making in adults. The impact of social influence appears to change during childhood, but the underlying mechanisms and their development remain unclear. We tested 125 neurotypical children between the ages of 6 and 14 years on a perceptual decision task…

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Stimulus complexity shapes response correlations in primary visual cortex [Neuroscience]

Spike count correlations (SCCs) are ubiquitous in sensory cortices, are characterized by rich structure, and arise from structured internal dynamics. However, most theories of visual perception treat contributions of neurons to the representation of stimuli independently and focus on mean responses. Here, we argue that, in a functional model of…

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REM sleep’s unique associations with corticosterone regulation, apoptotic pathways, and behavior in chronic stress in mice [Neuroscience]

One of sleep’s putative functions is mediation of adaptation to waking experiences. Chronic stress is a common waking experience; however, which specific aspect of sleep is most responsive, and how sleep changes relate to behavioral disturbances and molecular correlates remain unknown. We quantified sleep, physical, endocrine, and behavioral variables, as…

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Transgressive segregation reveals mechanisms of Arabidopsis immunity to Brassica-infecting races of white rust (Albugo candida) [Plant Biology]

Arabidopsis thaliana accessions are universally resistant at the adult leaf stage to white rust (Albugo candida) races that infect the crop species Brassica juncea and Brassica oleracea. We used transgressive segregation in recombinant inbred lines to test if this apparent species-wide (nonhost) resistance in A. thaliana is due to natural…

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Fluorescent reconstitution on deposition of PM2.5 in lung and extrapulmonary organs [Applied Biological Sciences]

The deposition of PM2.5 (fine particulate matter in air with diameter smaller than 2.5 μm) in lungs is harmful to human health. However, real-time observation on the deposition of particles in the acinar area of the lung is still a challenge in experiments. Here, a fluorescent imaging method is developed…

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Thickness scaling of ferroelectricity in BiFeO3 by tomographic atomic force microscopy [Applied Physical Sciences]

Nanometer-scale 3D imaging of materials properties is critical for understanding equilibrium states in electronic materials, as well as for optimization of device performance and reliability, even though such capabilities remain a substantial experimental challenge. Tomographic atomic force microscopy (TAFM) is presented as a subtractive scanning probe technique for high-resolution, 3D…

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Flow interactions between uncoordinated flapping swimmers give rise to group cohesion [Applied Physical Sciences]

Many species of fish and birds travel in groups, yet the role of fluid-mediated interactions in schools and flocks is not fully understood. Previous fluid-dynamical models of these collective behaviors assume that all individuals flap identically, whereas animal groups involve variations across members as well as active modifications of wing…

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Peptidic degron for IMiD-induced degradation of heterologous proteins [Biochemistry]

Current systems for modulating the abundance of proteins of interest in living cells are powerful tools for studying protein function but differ in terms of their complexity and ease of use. Moreover, no one system is ideal for all applications, and the best system for a given protein of interest…

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Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds [Biochemistry]

The RAS gene family is frequently mutated in human cancers, and the quest for compounds that bind to mutant RAS remains a major goal, as it also does for inhibitors of protein–protein interactions. We have refined crystallization conditions for KRAS169Q61H-yielding crystals suitable for soaking with compounds and exploited this to…

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Thermodynamically reversible paths of the first fusion intermediate reveal an important role for membrane anchors of fusion proteins [Biophysics and Computational Biology]

Biological membrane fusion proceeds via an essential topological transition of the two membranes involved. Known players such as certain lipid species and fusion proteins are generally believed to alter the free energy and thus the rate of the fusion reaction. Quantifying these effects by theory poses a major challenge since…

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Real-time dissection of dynamic uncoating of individual influenza viruses [Biophysics and Computational Biology]

Uncoating is an obligatory step in the virus life cycle that serves as an antiviral target. Unfortunately, it is challenging to study viral uncoating due to methodology limitations for detecting this transient and dynamic event. The uncoating of influenza A virus (IAV), which contains an unusual genome of eight segmented…

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Transcription factor regulation of RNA polymerase’s torque generation capacity [Biophysics and Computational Biology]

During transcription, RNA polymerase (RNAP) supercoils DNA as it translocates. The resulting torsional stress in DNA can accumulate and, in the absence of regulatory mechanisms, becomes a barrier to RNAP elongation, causing RNAP stalling, backtracking, and transcriptional arrest. Here we investigate whether and how a transcription factor may regulate both…

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Quantification of reaction cycle parameters for an essential molecular switch in an auxin-responsive transcription circuit in rice [Biophysics and Computational Biology]

Protein-based molecular switches play critical roles in biological processes. The importance of the prolyl cis−trans switch is underscored by the ubiquitous presence of peptidyl prolyl isomerases such as cyclophilins that accelerate the intrinsically slow isomerization rate. In rice, a tryptophan−proline (W-P) cis−trans switch in transcription repressor protein OsIAA11 along with…

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Effects of knot tightness at the molecular level [Chemistry]

Three 819 knots in closed-loop strands of different lengths (∼20, 23, and 26 nm) were used to experimentally assess the consequences of knot tightness at the molecular level. Through the use of 1H NMR, diffusion-ordered spectroscopy (DOSY), circular dichroism (CD), collision-induced dissociation mass spectrometry (CID-MS) and molecular dynamics (MD) simulations…

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Impact of nuclear quantum effects on the structural inhomogeneity of liquid water [Chemistry]

The 2D Raman–terahertz (THz) response of liquid water is studied in dependence of temperature and isotope substitution (H2O, D2O, and H218O). In either case, a very short-lived (i.e., between 75 and 95 fs) echo is observed that reports on the inhomogeneity of the low-frequency intermolecular modes and hence, on the…

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Zn-dependent bifunctional proteases are responsible for leader peptide processing of class III lanthipeptides [Chemistry]

Lanthipeptides are an important subfamily of ribosomally synthesized and posttranslationally modified peptides, and the removal of their N-terminal leader peptides by a designated protease(s) is a key step during maturation. Whereas proteases for class I and II lanthipeptides are well-characterized, the identity of the protease(s) responsible for class III leader…

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Dynamics of geologic CO2 storage and plume motion revealed by seismic coda waves [Earth, Atmospheric, and Planetary Sciences]

Quantifying the dynamics of sequestered CO2 plumes is critical for safe long-term storage, providing guidance on plume extent, and detecting stratigraphic seal failure. However, existing seismic monitoring methods based on wave reflection or transmission probe a limited rock volume and their sensitivity decreases as CO2 saturation increases, decreasing their utility…

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Influences of light and humidity on carbonyl sulfide-based estimates of photosynthesis [Earth, Atmospheric, and Planetary Sciences]

Understanding climate controls on gross primary productivity (GPP) is crucial for accurate projections of the future land carbon cycle. Major uncertainties exist due to the challenge in separating GPP and respiration from observations of the carbon dioxide (CO2) flux. Carbonyl sulfide (COS) has a dominant vegetative sink, and plant COS…

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North America’s oldest boreal trees are more efficient water users due to increased [CO2], but do not grow faster [Earth, Atmospheric, and Planetary Sciences]

Due to anthropogenic emissions and changes in land use, trees are now exposed to atmospheric levels of [CO2] that are unprecedented for 650,000 y [Lüthi et al. (2008) Nature 453:379–382] (thousands of tree generations). Trees are expected to acclimate by modulating leaf–gas exchanges and alter water use efficiency which may…

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Regional neutrality evolves through local adaptive niche evolution [Ecology]

Biodiversity in natural systems can be maintained either because niche differentiation among competitors facilitates stable coexistence or because equal fitness among neutral species allows for their long-term cooccurrence despite a slow drift toward extinction. Whereas the relative importance of these two ecological mechanisms has been well-studied in the absence of…

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Realizing the potential of dielectric elastomer artificial muscles [Engineering]

Soft robotics represents a new set of technologies aimed at operating in natural environments and near the human body. To interact with their environment, soft robots require artificial muscles to actuate movement. These artificial muscles need to be as strong, fast, and robust as their natural counterparts. Dielectric elastomer actuators…

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Directional pumping of water and oil microdroplets on slippery surface [Engineering]

Transporting water and oil microdroplets is important for applications ranging from water harvesting to biomedical analysis but remains a great challenge. This is due to the amplified contact angle hysteresis and insufficient driving force in the micrometer scale, especially for low-surface energy oil droplets. Coalescence of neighboring droplets, which releases…

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Stratification of reactivity determines nitrate removal in groundwater [Environmental Sciences]

Biogeochemical reactions occur unevenly in space and time, but this heterogeneity is often simplified as a linear average due to sparse data, especially in subsurface environments where access is limited. For example, little is known about the spatial variability of groundwater denitrification, an important process in removing nitrate originating from…

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Transitions between foot postures are associated with elevated rates of body size evolution in mammals [Evolution]

Terrestrial mammals have evolved various foot postures: flat-footed (plantigrady), tiptoed (digitigrady), and hooved (unguligrady) postures. Although the importance of foot posture on ecology and body size of mammalian species has been widely recognized, its evolutionary trajectory and influence on body size evolution across mammalian phylogeny remain untested. Taking a Bayesian…

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Genetically modified hematopoietic stem/progenitor cells that produce IL-10-secreting regulatory T cells [Immunology and Inflammation]

Random amino acid copolymers used in the treatment of multiple sclerosis in man or experimental autoimmune encephalomyelitis (EAE) in mice [poly(Y,E,A,K)n, known as Copaxone, and poly(Y,F,A,K)n] function at least in part by generation of IL-10–secreting regulatory T cells that mediate bystander immunosuppression. The mechanism through which these copolymers induce Tregs…

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Reprogramming responsiveness to checkpoint blockade in dysfunctional CD8 T cells [Immunology and Inflammation]

Established T cell dysfunction is a barrier to antitumor responses, and checkpoint blockade presumably reverses this. Many patients fail to respond to treatment and/or develop autoimmune adverse events. The underlying reason for T cell responsiveness remains elusive. Here, we show that susceptibility to checkpoint blockade is dependent on the activation…

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IL-33/regulatory T cell axis triggers the development of a tumor-promoting immune environment in chronic inflammation [Immunology and Inflammation]

Chronic inflammation’s tumor-promoting potential is well-recognized; however, the mechanism underlying the development of this immune environment is unknown. Studying the transition from acute, tumor-suppressive to chronic, tumor-promoting allergic contact dermatitis (ACD) revealed how tumor-promoting chronic inflammation develops. Epidermis-derived interleukin (IL)-33 up-regulation and its induct

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The glutathione cycle shapes synaptic glutamate activity [Neuroscience]

Glutamate is the most abundant excitatory neurotransmitter, present at the bulk of cortical synapses, and participating in many physiologic and pathologic processes ranging from learning and memory to stroke. The tripeptide, glutathione, is one-third glutamate and present at up to low millimolar intracellular concentrations in brain, mediating antioxidant defenses and…

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Inositol polyphosphate multikinase mediates extinction of fear memory [Neuroscience]

Inositol polyphosphate multikinase (IPMK), the key enzyme for the biosynthesis of higher inositol polyphosphates and phosphatidylinositol 3,4,5-trisphosphate, also acts as a versatile signaling player in regulating tissue growth and metabolism. To elucidate neurobehavioral functions of IPMK, we generated mice in which IPMK was deleted from the excitatory neurons of the…

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Effective connectivity changes in LSD-induced altered states of consciousness in humans [Pharmacology]

Psychedelics exert unique effects on human consciousness. The thalamic filter model suggests that core effects of psychedelics may result from gating deficits, based on a disintegration of information processing within cortico–striato–thalamo-cortical (CSTC) feedback loops. To test this hypothesis, we characterized changes in directed (effective) connectivity between selected CTSC regions after…

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Opinion: “Plan S” falls short for society publishers—and for the researchers they serve [Physics]

Over the course of my long scientific career, I have had experience with academic publishing from several perspectives: as an author, as an associate editor of both academic and for-profit journals, as chair of a society’s journals board, as editor-in-chief of a major society journal (Science), and now as the…

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Actuation of magnetoelastic membranes in precessing magnetic fields [Physics]

Superparamagnetic nanoparticles incorporated into elastic media offer the possibility of creating actuators driven by external fields in a multitude of environments. Here, magnetoelastic membranes are studied through a combination of continuum mechanics and molecular dynamics simulations. We show how induced magnetic interactions affect the buckling and the configuration of magnetoelastic…

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Limits of multifunctionality in tunable networks [Physics]

Nature is rife with networks that are functionally optimized to propagate inputs to perform specific tasks. Whether via genetic evolution or dynamic adaptation, many networks create functionality by locally tuning interactions between nodes. Here we explore this behavior in two contexts: strain propagation in mechanical networks and pressure redistribution in…

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Enhanced resistance to bacterial and oomycete pathogens by short tandem target mimic RNAs in tomato [Plant Biology]

Nucleotide binding site leucine-rich repeat (NLR) proteins of the plant innate immune system are negatively regulated by the miR482/2118 family miRNAs that are in a distinct 22-nt class of miRNAs with a double mode of action. First, they cleave the target RNA, as with the canonical 21-nt miRNAs, and second,…

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Maternal small RNAs mediate spatial-temporal regulation of gene expression, imprinting, and seed development in Arabidopsis [Plant Biology]

Arabidopsis seed development involves maternal small interfering RNAs (siRNAs) that induce RNA-directed DNA methylation (RdDM) through the NRPD1-mediated pathway. To investigate their biological functions, we characterized siRNAs in the endosperm and seed coat that were separated by laser-capture microdissection (LCM) in reciprocal genetic crosses with an nrpd1 mutant. We also…

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Fighting misinformation on social media using crowdsourced judgments of news source quality [Psychological and Cognitive Sciences]

Reducing the spread of misinformation, especially on social media, is a major challenge. We investigate one potential approach: having social media platform algorithms preferentially display content from news sources that users rate as trustworthy. To do so, we ask whether crowdsourced trust ratings can effectively differentiate more versus less reliable…

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The impact of income, land, and wealth inequality on agricultural expansion in Latin America [Sustainability Science]

Agricultural expansion remains the most prominent proximate cause of tropical deforestation in Latin America, a region characterized by deforestation rates substantially above the world average and extremely high inequality. This paper deploys several multivariate statistical models to test whether different aspects of inequality, within a context of increasing agricultural productivity,…

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Correction for Su et al., Pyruvate cycle increases aminoglycoside efficacy and provides respiratory energy in bacteria [Corrections]

MICROBIOLOGY Correction for “Pyruvate cycle increases aminoglycoside efficacy and provides respiratory energy in bacteria,” by Yu-bin Su, Bo Peng, Hui Li, Zhi-xue Cheng, Tian-tuo Zhang, Jia-xin Zhu, Dan Li, Min-yi Li, Jin-zhou Ye, Chao-chao Du, Song Zhang, Xian-liang Zhao, Man-jun Yang, and Xuan-xian Peng, which was first published January 30,…

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Correction to Supporting Information for Griscom et al., Natural climate solutions [SI Correction]

EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES, SUSTAINABILITY SCIENCE Correction to Supporting Information for “Natural climate solutions,” by Bronson W. Griscom, Justin Adams, Peter W. Ellis, Richard A. Houghton, Guy Lomax, Daniela A. Miteva, William H. Schlesinger, David Shoch, Juha V. Siikamäki, Pete Smith, Peter Woodbury, Chris Zganjar, Allen Blackman, João Campari,…

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In This Issue [This Week in PNAS]

Visualizing flu virus uncoating in infected cells Transmission electron micrograph of IAV virions encapsulating quantum dots. The genome of influenza A virus (IAV) comprises eight segmented RNA strands enclosed in a coat. During infection, the virus is uncoated in the cytoplasm of host cells, viral RNA is imported into the…

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Ontogenetic deepening of Northeast Atlantic fish stocks is not driven by fishing exploitation [Biological Sciences]

For many marine fish species, the average size of individuals increases with depth. This phenomenon, first described a century ago, is known as ontogenetic deepening (1, 2). Several mechanisms have been proposed to explain it: optimal foraging; predation avoidance; and different optimal growth temperature for larger individuals, causing them to…

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Reply to Baudron et al.: Fishing matters: Age-specific deepening is driven by exploitation [Biological Sciences]

In their response to our paper “Exploitation drives an ontogenetic-like deepening in marine fish” (1), Baudron et al. (2) unfairly characterize our result as an alternative explanation. Throughout our paper, and in the closing remark, we explicitly state that additional factors must be considered: “Ontogenetic factors, fisheries exploitation, and climate…

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What's So Special About the Atacama Desert?

Northern Chile's dry and desolate Atacama Desert hosts the world's largest array of astronomical observatories. Scientists have called the largely lifeless region Earth's closest analogue of Mars.

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Teleconnections and environmental determinism: Was there really a climate-driven collapse at Late Neolithic Catalhoyuk? [Letters (Online Only)]

In PNAS, Roffet-Salque et al. (1) present an innovative paleoclimatic reconstruction using biomarkers to suggest that δ2H measurements on animal fat residues from pottery vary through time at the important Neolithic site of Çatalhöyük. The interpretation of these changes in relation to a teleconnection with the 8.2-kyBP climate event is…

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Reply to Wainwright and Ayala: Synchronicity of climate and cultural proxies around 8.2 kyBP at Catalhoyuk [Letters (Online Only)]

We are surprised at Wainwright and Ayala’s (1) unjustified critique of our recent report in PNAS (2). First, we openly acknowledge that the changes in δ2H18:0 values are not statistically significant; indeed, we report a P value of 0.10 (t test) and a relatively high SD within each phase (7‰)…

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From 2D to 3D: Strain- and elongation-free topological transformations of optoelectronic circuits [Engineering]

Optoelectronic circuits in 3D shapes with large deformations can offer additional functionalities inaccessible to conventional planar electronics based on 2D geometries constrained by conventional photolithographic patterning processes. A light-sensing focal plane array (FPA) used in imagers is one example of a system that can benefit from fabrication on curved surfaces….

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Polar molecules catalyze CO insertion into metal-alkyl bonds through the displacement of an agostic C-H bond [Chemistry]

The insertion of CO into metal-alkyl bonds is the key C-C bond-forming step in many of the most important organic reactions catalyzed by transition metal complexes. Polar organic molecules (e.g., tetrahydrofuran) have long been known to promote CO insertion reactions, but the mechanism of their action has been the subject…

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Crystal structure of MICU2 and comparison with MICU1 reveal insights into the uniporter gating mechanism [Biochemistry]

The mitochondrial uniporter is a Ca2+-channel complex resident within the organelle’s inner membrane. In mammalian cells the uniporter’s activity is regulated by Ca2+ due to concerted action of MICU1 and MICU2, two paralogous, but functionally distinct, EF-hand Ca2+-binding proteins. Here we present the X-ray structure of the apo form of…

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Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling [Engineering]

Breast cancer development is associated with increasing tissue stiffness over years. To more accurately mimic the onset of gradual matrix stiffening, which is not feasible with conventional static hydrogels, mammary epithelial cells (MECs) were cultured on methacrylated hyaluronic acid hydrogels whose stiffness can be dynamically modulated from “normal” (<150 Pascals)…

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Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma [Medical Sciences]

Scleroderma (SSc) is a complex disease that involves activation of the immune system, vascular complications, and tissue fibrosis. The histone methyltransferase enhancer of zeste homolog 2 (EZH2) mediates trimethylation of lysine 27 of histone 3 (H3K27me3), which acts as a repressive epigenetic mark. Both EZH2 and H3K27me3 were elevated in…

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Stage-dependent cardiac regeneration in Xenopus is regulated by thyroid hormone availability [Developmental Biology]

Despite therapeutic advances, heart failure is the major cause of morbidity and mortality worldwide, but why cardiac regenerative capacity is lost in adult humans remains an enigma. Cardiac regenerative capacity widely varies across vertebrates. Zebrafish and newt hearts regenerate throughout life. In mice, this ability is lost in the first…

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Bacterial lipolysis of immune-activating ligands promotes evasion of innate defenses [Microbiology]

Commensal and pathogenic bacteria hydrolyze host lipid substrates with secreted lipases and phospholipases for nutrient acquisition, colonization, and infection. Bacterial lipase activity on mammalian lipids and phospholipids can promote release of free fatty acids from lipid stores, detoxify antimicrobial lipids, and facilitate membrane dissolution. The gram-positive bacterium Staphylococcus aure

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Cold sensing by NaV1.8-positive and NaV1.8-negative sensory neurons [Neuroscience]

The ability to detect environmental cold serves as an important survival tool. The sodium channels NaV1.8 and NaV1.9, as well as the TRP channel Trpm8, have been shown to contribute to cold sensation in mice. Surprisingly, transcriptional profiling shows that NaV1.8/NaV1.9 and Trpm8 are expressed in nonoverlapping neuronal populations. Here…

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PILS6 is a temperature-sensitive regulator of nuclear auxin input and organ growth in Arabidopsis thaliana [Plant Biology]

Temperature modulates growth and development throughout the entire lifecycle of a plant. High temperature (HT) triggers the auxin biosynthesis-dependent growth in aerial tissues. On the other hand, the contribution of auxin to HT-induced root growth is currently under debate. Here we show that the putative intracellular auxin carrier PIN-LIKES 6…

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Kinetics of trifurcated electron flow in the decaheme bacterial proteins MtrC and MtrF [Chemistry]

The bacterium Shewanella oneidensis has evolved a sophisticated electron transfer (ET) machinery to export electrons from the cytosol to extracellular space during extracellular respiration. At the heart of this process are decaheme proteins of the Mtr pathway, MtrC and MtrF, located at the external face of the outer bacterial membrane….

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Additive manufacturing of patterned 2D semiconductor through recyclable masked growth [Engineering]

The 2D van der Waals crystals have shown great promise as potential future electronic materials due to their atomically thin and smooth nature, highly tailorable electronic structure, and mass production compatibility through chemical synthesis. Electronic devices, such as field effect transistors (FETs), from these materials require patterning and fabrication into…

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Mid-infrared feed-forward dual-comb spectroscopy [Physics]

Mid-infrared high-resolution spectroscopy has proven an invaluable tool for the study of the structure and dynamics of molecules in the gas phase. The advent of frequency combs advances the frontiers of precise molecular spectroscopy. Here we demonstrate, in the important 3-µm spectral region of the fundamental CH stretch in molecules,…

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Cortical route for facelike pattern processing in human newborns [Psychological and Cognitive Sciences]

Humans are endowed with an exceptional ability for detecting faces, a competence that, in adults, is supported by a set of face-specific cortical patches. Human newborns, already shortly after birth, preferentially orient to faces, even when they are presented in the form of highly schematic geometrical patterns vs. perceptually equivalent…

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Physical exertion exacerbates decline in the musculature of an animal model of Duchenne muscular dystrophy [Applied Biological Sciences]

Duchenne muscular dystrophy (DMD) is a genetic disorder caused by loss of the protein dystrophin. In humans, DMD has early onset, causes developmental delays, muscle necrosis, loss of ambulation, and death. Current animal models have been challenged by their inability to model the early onset and severity of the disease….

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Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in SLC6A3 [Neuroscience]

The human dopamine (DA) transporter (hDAT) mediates clearance of DA. Genetic variants in hDAT have been associated with DA dysfunction, a complication associated with several brain disorders, including autism spectrum disorder (ASD). Here, we investigated the structural and behavioral bases of an ASD-associated in-frame deletion in hDAT at N336 (∆N336)….

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Epigenomic analysis reveals DNA motifs regulating histone modifications in human and mouse [Genetics]

Histones are modified by enzymes that act in a locus, cell-type, and developmental stage-specific manner. The recruitment of enzymes to chromatin is regulated at multiple levels, including interaction with sequence-specific DNA-binding factors. However, the DNA-binding specificity of the regulatory factors that orchestrate specific histone modifications has not been broadly mapped….

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Scientists provide new insight on gene mutations associated with autism

A novel investigation into the impacts of neuronal mutations on autism-related characteristics in humans has been described.

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Accelerated risk of mobility loss for people aged 60+ tied to excess weight/inactivity

The combination of excess weight/obesity and an inactive lifestyle represents a powerful joint risk factor for developing mobility loss after age 60, according to a new study.

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New AI toolkit is the 'scientist that never sleeps'

Researchers have developed a new AI-driven platform that can analyze how pathogens infect our cells with the precision of a trained biologist.

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Trilobites: What’s Pink and Pinstriped and Digests Wood? This New Shipworm

Scientists are eager to learn more about the bacteria that live in this recently-discovered clam with an extremely-long digestive system.

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NASA Once Made an Official Ruling on Women and Pantsuits

In 1970, NASA’s Goddard Spaceflight Centre was forced to address a tricky new issue in the realm of women in space: the validity of pants in the workplace. Women and pants have a strange relationship throughout the 20th century, and further back, too, though for the moment we aren't going to get into Joan of Arc wearing men's armour. Pants — or trousers or slacks — began the last century as men's

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Ancient Celts Decapitated Their Enemies and Saved Their Heads, Archaeologists Say

(Inside Science) — In a finding that mirrors the fantasy of HBO's “Game of Thrones,” French researchers working at the site of a third-century B.C. settlement have discovered evidence that Celtic communities decapitated and preserved human heads. A team of archaeologists unearthed fragments of human skulls that they believe confirm a practice of deliberate decapitation. They concluded that the sk

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Giant leap for art: Lichfield Cathedral to become 'lunar landscape'

Installation will transform cathedral floor to mark 50 years since Apollo 11 moon landing It’s hard to imagine anything less like a lunar landscape than the medieval glories of Lichfield Cathedral. But this summer, an artist will transform its magnificent tiled floor into a representation of the moon’s surface to mark half a century since Neil Armstrong took “one small step for [a] man and one gi

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Where Do New Languages Come From?

In the desert town of Lajamanu, Australia, at the bend of a narrow dirt road, Carmel O’Shannessy worked at a school as a teacher-linguist in the early 2000s. Lajamanu’s Indigenous Warlpiri people, who live in the country’s Northern Territory, were skilled at drawing sustenance from the landscape’s parched red soil, and O’Shannessy soon discovered hidden cultural riches the Warlpiri had stored up.

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Artificial "Dumbness" May Be a Solution for Engineering Smart Machines

Design principles derived from observing fruit flies may lead to better self-driving cars and improved Parkinson’s treatment — Read more on ScientificAmerican.com

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New tarantula species from Angola distinct with a one-of-a-kind 'horn' on its back

A new to science species of tarantula with a peculiar horn-like protuberance sticking out of its back was recently identified from Angola, a largely underexplored country located at the intersection …

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Turn down the volume: WHO takes aim at harmful smartphone use

More than one billion young people risk damaging their hearing through excessive use of smartphones and other audio devices, the UN warned Tuesday, proposing new safety standards for safe volume levels.

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Walking simulation games signal a new literary genre

Walking simulation games signal a new literary genre Research has revealed that walking simulations are blurring the boundaries of different art forms to create a new literary genre. Walking simulations — video games where there are no winners and no one is shot at or killed — have become increasingly popular in the last few years.

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Improving geothermal HVAC systems with mathematics

Sustainable heating, ventilation, and air conditioning systems, such as those that harness low-enthalpy geothermal energy, are needed to reduce collective energy use and mitigate the continued effects of a warming climate. Researchers use asymptotic expansion techniques to study the harmonic thermal response of vertical geothermal boreholes in such systems to sub-annual harmonic excitations.

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Artificial "Dumbness" May Be a Solution for Engineering Smart Machines

Design principles derived from observing fruit flies may lead to better self-driving cars and improved Parkinson’s treatment — Read more on ScientificAmerican.com

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40 countries agree cars must have automatic braking

Forty countries led by Japan and the European Union—but not the U.S. or China—have agreed to require new cars and light commercial vehicles to be equipped with automated braking systems starting as soon as next year, a U.N. agency said Tuesday.

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By 2080, Washington D.C. climate may feel like Deep South

In a single generation, climate patterns will shift hundreds of kilometres in the United States, according to a study tracking the northward drift of hotter climes brought on by climate change and global warming.

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Pitch perfect: Strategic language use maximizes the chances of influencing an audience

For even the most stoic entrepreneur, facing a panel of potential investors can be like walking onto the set of 'Dragon's Den'.

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38 percent off a Roomba and other good deals happening today

Gadgets A quick guide to getting the goods for cheaper. Our lists will be updated throughout the day, so check back to see if stumbled upon any awesome new discounts.

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Artificial "Dumbness" May Be a Solution for Engineering Smart Machines

Design principles derived from observing fruit flies may lead to better self-driving cars and improved Parkinson’s treatment — Read more on ScientificAmerican.com

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New Idea to Land Heavy Payloads on Mars: Dive, Then Turn Nose Up

Seven Minutes of Terror Landing a spacecraft on the surface of Mars is a Herculean task. Payloads reach hypersonic speeds as they heat up while entering the Martian atmosphere — the reason scientists have referred to it as the “seven minutes of terror.” Many spacecraft have slowed their descents to Mars using large parachutes. But landing heavier spacecraft on the Red Planet, like those with a hu

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New study suggests possibility of recent underground volcanism on Mars

A study published last year in the journal Science suggested liquid water is present beneath the south polar ice cap of Mars. Now, a new study in the AGU journal Geophysical Research Letters argues there needs to be an underground source of heat for liquid water to exist underneath the polar ice cap.

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Nano drops a million times smaller than a teardrop explodes 19th century theory

Droplets emanating from a molecular 'nano-tap' would behave very differently from those from a household tap 1 million times larger — researchers have found. This is potentially crucial step for a number of emerging nano technologies, e.g., manufacture of nano-sized drug particles, lab-on-chip devices for in situ diagnostics, and 3D printers capable of nanoscale resolution.

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Questions in quantum computing: How to move electrons with light

To design future quantum technologies, scientists pinpoint how microwaves interact with matter.

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Nano drops a million times smaller than a teardrop explodes 19th century theory

Droplets emanating from a molecular 'nano-tap' would behave very differently from those from a household tap 1 million times larger — researchers have found. This is potentially crucial step for a number of emerging nano technologies, e.g., manufacture of nano-sized drug particles, lab-on-chip devices for in situ diagnostics, and 3D printers capable of nanoscale resolution.

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Cancer comparison across species highlights new drug targets

Cancer genes in mucosal melanoma, a rare and poorly understood subtype of melanoma, have been compared in humans, dogs and horses for the first time. Researchers sequenced the genomes of the same cancer across different species to pinpoint key cancer genes. The results give insights into how cancer evolves across the tree of life and could guide the development of new therapies.

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How Viagra puts a brake on a master growth regulator to treat heart disease

When normal cells grow, divide or do any job in the body, they do so in response to a whole slew of internal sensors that measure nutrients and energy supply, and environmental cues that inform what happens outside the cell.

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Mom's reward: Female Galápagos seabird has a shorter lifespan than males

The male Nazca booby, a large seabird of the Galápagos Islands, often outlives the domineering female of the species, according to new research. Why? It's a story of rotating sex partners, the cost of being a parent and how the body falls apart in old age.

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New tarantula species from Angola distinct with a one-of-a-kind 'horn' on its back

A new to science species of tarantula with a peculiar horn-like protuberance sticking out of its back was recently identified in central Angola, a largely underexplored country located at the intersection of several Afrotropical ecoregions.

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Consciousness rests on the brain's ability to sustain rich dynamics of neural activity

Consciousness, from the moment we go to sleep until we wake up, seems to come and go every day. Consciousness can be temporarily abolished by pharmacological agents or more permanently by brain injury. Each of these departures from conscious wakefulness brings about different changes in brain function, behavior and in the brain's neurochemistry. However, they all share a common feature: the lack o

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Questions in quantum computing: How to move electrons with light

To design future quantum technologies, scientists pinpoint how microwaves interact with matter.

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Regenerative medicine growing strong in Northeast Ohio, elsewhere

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German airport creates an autonomous flying taxi

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Engineers Are Using AI to Predict How New, Unknown Materials Will Perform

Researchers at MIT have used AI to predict the behavior of materials. This approach could yield substantial dividends in the long term. The post Engineers Are Using AI to Predict How New, Unknown Materials Will Perform appeared first on ExtremeTech .

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A "Green New Deal" Is Already Taking Shape at the State Level

Several states are working to decarbonize their electric sectors with options from solar power to nuclear energy — Read more on ScientificAmerican.com

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Tesla Driver Claims Autopilot Wouldn’t Let Him Prevent Crash

Driver’s Seat On Sunday night, a Tesla crashed in North Brunswick, New Jersey, reportedly veering off the road and hitting several signs before finally stopping. The driver wasn’t hurt, but the vehicle did sustain extensive damage. It wasn’t a particularly remarkable accident, other than the fact that the driver claims he could have prevented it — if Autopilot would have let him. Blame Game Accor

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The US plans to launch swarms of attack drones from robo-submarines

The US Navy has a project that plans to use an autonomous submarine to launch a swarm of attack drones from underwater

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Why it matters to call external female genitalia ‘vulva’ not ‘vagina’ | Lynn Enright

Yes, some people use the term vagina, but getting it right is vital to female sexual agency When you find yourself mansplaining the term “mansplaining” to a worked-up faction of Twitter on a Sunday evening, you can assume you’re not getting the best out of your leisure time. And that’s not even the most foolish thing a man called Paul Bullen did over the weekend. On Saturday, the Guardian publishe

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Technology could make a hard border disappear, but at a cost

Background surveillance would need to be high

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AI has helped rescue children trafficked for sexual exploitation

Investigators are using artificial intelligence to locate children who have been trafficked for sexual exploitation

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The unexpected creates reward when listening to music

If you love it when a musician strikes that unexpected but perfect chord, you are not alone. New research shows the musically unexpected activates the reward centre of our brains, and makes us learn about the music as we listen.

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New study suggests possibility of recent underground volcanism on Mars

A study published last year in the journal Science suggested liquid water is present beneath the south polar ice cap of Mars. Now, a new study in the AGU journal Geophysical Research Letters argues there needs to be an underground source of heat for liquid water to exist underneath the polar ice cap.

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Time-shift TV doesn’t keep people from watching ads

People with time-shift TV don’t watch any less live TV—or advertisements—than they did before they had it, according to a new study. In fact, the study finds that people watch slightly more TV overall than they did before having the technology, which allows people to watch TV shows they missed without presetting devices to record them. “Advertisers have been concerned that using time-shift TV wou

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DNA test could boost IVF success rates without putting embryo at risk

Analysing genetic material discarded by an embryo in a dish can reveal chromosomal abnormalities just as well as a more invasive biopsy

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Consumers can save dramatically on wireless by skipping unlimited

If you're wondering how a tiny local wireless startup can afford to offer monthly wireless service that's a good two-thirds less than comparable plans from Verizon, AT&T and other carriers, it comes down to this: location, location, location.

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The One Change That Boosts a High School's Academic Performance

A study in Seattle shows the power of starting the day later — Read more on ScientificAmerican.com

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The East Coast Is Going to Get Arkansas-ified

Sixty years from now, climate change could transform the East Coast into the Gulf Coast. It will move Minnesota to Kansas, turn Tulsa into Texas, and hoist Houston into Mexico. Even Oregonians might ooze out of their damp, chilly corner and find themselves carried to the central valley of California. These changes won’t happen literally, of course—but that doesn’t make them any less real. A new p

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Apple Patented Facial Recognition to Unlock Your Car

Robotic Chivalry A newly-published patent shows that Apple obtained the rights to a facial recognition system that would allow your car to recognize you as you approach. Such a system would let cars unlock their doors when they see a registered user approach — and maybe even remember how each person likes to position the driver’s seat and mirrors. Post-Axing Don’t hold your breath for smart cars

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The One Change That Boosts a High School's Academic Performance

A study in Seattle shows the power of starting the day later — Read more on ScientificAmerican.com

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Without ancient star, Earth could be a icy, watery wasteland

Earth’s solid surface and mild climate may be partly due to a massive star in the birth environment of the sun, according to new research. Without the star’s injecting radioactive elements into the early solar system, our home planet could be a hostile ocean world covered in global ice sheets, the researchers say. “So, it seems we were just extraordinarily lucky. Were we? Or are there systematic

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Animals feel pain. Why do people believe they don't?

As part of the EU Withdrawal Bill, British MPs refused to recognize animal sentience. Yet it is well-documented that animals feel a range of feelings, including pain. The delusional idea that only humans experience emotions has lead to a variety of catastrophic problems, such as mass factory farming None As a child I loved Rick Raccoon. He was the only stuffed animal I owned of the Shirt Tales cr

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Pioneering black scientist to win Nobel Prize of climate change

Nexus Media News Climate scientist Warren Washington will be awarded the Tyler Prize for Environmental Achievement. Warren Washington is a legend for his pioneering work in the field of climate science. Now, he will be recognized with the Tyler Prize for Environmental Achievement.

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Seasonal Affective Disorder: SAD Symptoms and Therapy

Seasonal affective disorder (SAD) has the same symptoms and severity as clinical depression, only experts know when it starts and ends. Most sufferers have symptoms over fall and winter months, but a small percentage experience SAD during summer.

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Teaching self-driving cars to predict pedestrian movement

By zeroing in on humans' gait, body symmetry and foot placement, University of Michigan researchers are teaching self-driving cars to recognize and predict pedestrian movements with greater precision than current technologies.

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Gallbladder removal operation during pregnancy associated with adverse maternal outcomes

When faced with painful gallstones, pregnant women should consider postponing surgical treatment until after childbirth, new Journal of the American College of Surgeons study results show.

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Get the latest on UVA's artificial pancreas with testing nearly complete

A University of Virginia School of Medicine researcher will provide updates on a UVA-developed artificial pancreas — including early results from a nationwide clinical trial — during a presentation at the AAAS Annual Meeting. The presentation from Boris Kovatchev, PhD, director of the UVA Center for Diabetes Technology, is scheduled for 1:30-2 p.m. Feb. 15.

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With age comes hearing loss and a greater risk of cognitive decline

In a new study, researchers at University of California San Diego School of Medicine report that hearing impairment is associated with accelerated cognitive decline with age, though the impact of mild hearing loss may be lessened by higher education.

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Pitch perfect: Strategic language use maximizes the chances of influencing an audience

Research finds four interconnected language strategies that entrepreneurs employ to best influence their audience.

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German energy grids say plans ready for 100MW hydrogen plant

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Daily briefing: Meet the ‘hidden figures’ of genetics uncovered in the footnotes

Daily briefing: Meet the ‘hidden figures’ of genetics uncovered in the footnotes Daily briefing: Meet the ‘hidden figures’ of genetics uncovered in the footnotes, Published online: 12 February 2019; doi:10.1038/d41586-019-00571-6 Unsung female programmers and statisticians, violent drug cartels stifle Mexican science and essential elements for high-impact scientific writing

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When Cancer Threatens a Woman's Fertility

Solutions exist, but they’re costly—and 45 states don’t require that insurance cover them — Read more on ScientificAmerican.com

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Depression During and After Pregnancy Can Be Prevented, National Panel Says. Here’s How.

The task force of experts recommended at-risk women seek certain types of counseling, and it cited two specific programs that have been particularly effective.

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Isn’t It Romantic Fails as Both Rom-Com and Satire

The romantic comedy has been in a state of moderate crisis for the better part of a decade. After spending the early aughts making easy money with pairings of largely interchangeable stars—Kate Hudson, Matthew McConaughey, Katherine Heigl, Hugh Grant, Drew Barrymore, Adam Sandler, Jennifer Lopez … —rom-coms saw their box-office wave dry up abruptly around 2012. As the producer Lynda Obst, a doyen

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Animals feel pain. Why do people believe they don't?

As part of the EU Withdrawal Bill, British MPs refused to recognize animal sentience. Yet it is well-documented that animals feel a range of emotions, including pain. The delusional idea that only humans experience emotions has lead to a variety of catastrophic problems. None As a child I loved Rick Raccoon. He was the only stuffed animal I owned of the Shirt Tales crew. The show was necessary Sa

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Couples creating art or playing board games release 'love hormone'

When couples play board games together or take a painting class with each other, their bodies release oxytocin — sometimes dubbed the 'hugging hormone.' But men wielding paintbrushes released twice as much or more as the level of women painters and couples playing games, a Baylor University study has found.

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Storm Clouds And Sunshine: How Florida Prepares For Climate Change

The state and its key industries are among the most at-risk of being decimated by our changing climate. (Image credit: Joe Raedle/Getty Images)

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IBM says AI debate loss is still a win

IBM conceded Tuesday its artificial intelligence-powered Project Debater lost a competition to a human debate champion but said the experience was an important milestone in efforts to get computers …

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When Cancer Threatens a Woman's Fertility

Solutions exist, but they’re costly—and 45 states don’t require that insurance cover them — Read more on ScientificAmerican.com

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Spain police seize over 200 stuffed endangered animals

Spanish police said Tuesday they had seized more than 200 stuffed endangered animals, including giraffes, rhinos, lions and tigers, from an illegal taxidermy workshop that was selling them online.

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No flights to or from Belgium due to strike on Wednesday

Belgian airspace was to be closed to all flights below 8,000 metres on Wednesday as a national strike threatened to bring the European country to a standstill.

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Climate of North American cities will shift hundreds of miles in one generation

In one generation, the climate experienced in many North American cities is projected to change to that of locations hundreds of miles away—or to a new climate unlike any found in North America today.

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Spain police seize over 200 stuffed endangered animals

Spanish police said Tuesday they had seized more than 200 stuffed endangered animals, including giraffes, rhinos, lions and tigers, from an illegal taxidermy workshop that was selling them online.

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Eating 'Ultraprocessed' Foods Linked with Early Death

So-called "ultraprocessed" foods — which are high in salt, sugar and other additives — are linked with an increased risk of early death, a new study finds.

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Diets consisting of fewer calories improve cell performance

Animal experiments have shown that caloric restriction causes cellular changes that can prevent diseases, the subject of a session at FAPESP Week London.

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Nature prefers asymmetrical pollen grains, study finds

A study published in Cell shows that plants favor the production of uneven, asymmetrical patterns on the surface of pollen grains over more symmetrical patterns.

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Climate of North American cities will shift hundreds of miles in one generation

In one generation, the climate experienced in many North American cities is projected to change to that of locations hundreds of miles away — or to a new climate unlike any found in North America today. A new study and interactive web application aim to help the public understand how climate change will impact the lives of people who live in urban areas of the United States and Canada.

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Mayo Clinic researchers develop more efficient system to reprogram stem cells

Induced pluripotent stem cells, the workhorse of many regenerative medicine projects, start out as differentiated cells that are reprogrammed to pluripotent stem cells by exposure to a complex set of genetic cocktails.

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Backstage at the Westminster Dog Show

NEW YORK, N.Y.— On ordinary days, Mara Flood and her 18-year-old daughter, Becca Flood, interact like any other mother and daughter might, but on days like today, they’re more like colleagues—and rivals. The Floods, who breed and handle smooth collies together , have brought their dogs Cherry (whose full name is SugarNSpice Cherry On Top), Poe (Travler SugarNSpice Witches Do Come Blue), and Tiger

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One Cheer for Maine’s Task Force on Police Killings

In Maine, police officers who use deadly force on the job are always justified in doing so—or at least that’s apparently the official position of the state attorney general’s office, where every deadly police shooting for the past 28 years has been dutifully reviewed, and the cops have always been found justified in their killings. Does that seem plausible? Last year, after a spike in police kill

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The Much-Heralded End of the Mueller Investigation

Everyone is saying it: The Mueller investigation is winding down . The acting attorney general declared the investigation “close to completion” during a press conference. His wife, Marci Whitaker, has also insisted that the special counsel’s investigation is “ wrapping up .” President Donald Trump’s nominee for attorney general, William Barr, testified before the Senate Judiciary Committee that,

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Finally Scrutinizing the Men Behind the Grammys’ Curtain

As the Grammys dragged into its fourth hour on Sunday night, the storied producer Jimmy Jam told the audience that it was time to pay tribute to yet another titan of music. Dolly Parton had already presided over her own medley and Diana Ross had thrown herself a birthday bash ; Aretha Franklin’s memorial was still to come . The recipient of the next fete, rather, would be Neil Portnow, the bespec

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A Very Relatable Moment on the International Space Station

Accidents happen during home-improvement projects, even in space. The mishap unfolded on the International Space Station, which orbits about 250 miles above Earth, circling the planet every hour and a half. Earlier this month, NASA astronauts had gathered in the bathroom to install a pair of stalls for an extra enclosure that would provide some more privacy. As they worked, they twisted off a met

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Nano drops explode 19th century theory

Droplets emanating from a molecular "nano-tap" would behave very differently from those from a household tap 1 million times larger—researchers at the University of Warwick have found. This is potentially crucial step for a number of emerging nano technologies, e.g., manufacture of nano-sized drug particles, lab-on-chip devices for in situ diagnostics, and 3-D printers capable of nanoscale resolut

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Alzheimer's: How do tau tangles grow?

Researchers use a mathematical model and lab experiments to unravel the process through which tangles of the protein tau grow in length.

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What government and business can do to protect our privacy

What can we do about looming threats to our privacy online and the theft of important personal information? Ari Trachtenberg has some ideas. Last year kicked off with Cambridge Analytica being exposed for acquiring access to private data on at least 87 million Facebook users and wrapped up with Marriott announcing that 500 million of its accounts had been hacked. Quora, MyFitnessPal, Google+, MyH

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Toyota's moonshot: Self-driving car for sale — in a year

submitted by /u/izumi3682 [link] [comments]

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3 Reasons You Might Hate Valentine's Day

Valentine's Day may be one of the most polarizing holidays on the calendar. Here's why it's hated.

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School climate strikes: share your videos and stories

If you’re taking part in this week’s YouthStrike4Climate event in the UK, we’d like to hear from you On 15 February students around the UK will be striking to protest against the government’s lack of action on the climate crisis. It’s the first YouthStrike4Climate event in the UK, following successful school strikes in Australia, Belgium, Switzerland and Germany. Related: Pupils’ climate change s

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A Human Debater Just Roasted IBM’s “Intelligent Debate” AI Onstage

Silver Medal Machines are creeping closer and closer to a real understanding of language with all of its nuances and subtext. But for now, the best machines still can’t compare to humanity — a shortcoming made clear at a high stakes debate on Monday evening. In one corner was Harish Natarajan, a finalist at the World Debating Championships in 2016. His opponent was Project Debater , an AI system

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How antibiotics used in factory farming destroy our microbiomes

More and more research nowadays links good gut flora to several health benefits, such as the inhibition of Alzheimer's to a fast metabolism. Since we're over prescribed antibiotics, and because much of the meat we consume comes from animals that were fed antibiotics, we are destroying much of the good bacteria, and often at the risk — because of our diets — of replenishing them. A well-rounded di

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Spørg Fagfolket: Hjælper zoneterapi med at sætte en fødsel i gang?

En læser tror ikke på, at zoneterapi hjælper til at sætte gang i en fødsel – og kæresten er rasende over hans skepsis. Er der noget om snakken? Det har vi spurgt en jordemoder om.

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Sony's PlayStation Classic slashed to $39.99

There’s good news and bad news to report regarding Sony’s miniature PlayStation Classic console. First, the good news – you can pick one up at Walmart for just $39.99, the lowest price we’ve …

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How Fancy Water Bottles Became a 21st-Century Status Symbol

The potential judgment of students can lead a teacher to do strange things. For Monique Mongeon, an arts educator in Toronto, her first job teaching adults sparked a small crisis of confidence. “I was in my mid-20s, and I was looking at things I could do to make myself feel like a person who had authority to stand in front of a bunch of other 20-somethings,” she says. After ruling out fancy bags

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Hyperbolic metamaterials enable nanoscale 'fingerprinting'

Hyperbolic metamaterials are artificially made structures that can be formed by depositing alternating thin layers of a conductor such as silver or graphene onto a substrate. One of their special abilities is supporting the propagation of a very narrow light beam, which can be generated by placing a nanoparticle on its top surface and illuminating it with a laser beam.

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Van Allen probes begin final phase of exploration in Earth's radiation belts

Two tough, resilient, NASA spacecraft have been orbiting Earth for the past six and a half years, flying repeatedly through a hazardous zone of charged particles around our planet called the Van Allen radiation belts. The twin Van Allen Probes, launched in August 2012, have confirmed scientific theories and revealed new structures and processes at work in these dynamic regions. Now, they're starti

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Streetcars don't guarantee heightened development activity, study finds

Cities considering investing in streetcar systems in an effort to bolster economic development should take caution, according to a study conducted by a University of Kansas urban planning researcher.

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Interactive Map Shows Where Your City is Going, Climatically Speaking

Interactive Map Shows Where Your City is Going, Climatically Speaking Researchers match recent and future climates to show what American cities will be like in 60 years. Pittsburgh-Skyline_cropped.jpg If climate change proceeds unchecked, the Pittsburgh of 2080 may feel like a recent northeastern Arkansas. Image credits: Briank93 via Shutterstock Earth Tuesday, February 12, 2019 – 11:00 Nala Roge

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This Startup Wants Its Fusion Reactor to Actually Produce Power

Holy Grail It’s the holy grail of the energy industry: fusion power, the same reaction that powers the Sun, that could deliver near-limitless clean electricity. The unfortunate reality, though, is that generating power from a fusion reaction still requires far more energy to be put in than it ever puts out in the form of usable power. But researchers at the First Light Fusion group in Oxford, UK

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Contemporary climatic analogs for 540 North American urban areas in the late 21st century

Contemporary climatic analogs for 540 North American urban areas in the late 21st century Contemporary climatic analogs for 540 North American urban areas in the late 21st century, Published online: 12 February 2019; doi:10.1038/s41467-019-08540-3 It is challenging to communicate abstract future climate estimates. Here the authors utilized climate-analog mapping and they identified that North Ame

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Ancient spider fossils, surprisingly preserved in rock, reveal reflective eyes

Usually, soft-bodied species like spiders aren't fossilized in rock like animals with bones and teeth. More often, ancient spiders and insects are more likely to be discovered preserved in amber.

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Mom's reward: Female Galapagos seabird has a shorter lifespan than males

The male Nazca booby, a large seabird of the Galápagos Islands, often outlives the domineering female of the species, according to new research from Wake Forest University published today in the Journal of Animal Ecology. Why? It's a story of rotating sex partners, the cost of being a parent and how the body falls apart in old age.

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New tarantula species from Angola distinct with a one-of-a-kind 'horn' on its back

A new to science species of tarantula with a peculiar horn-like protuberance sticking out of its back was recently identified from Angola, a largely underexplored country located at the intersection of several Afrotropical ecoregions.

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Laser physics: Transformation through light

Laser physicists have taken snapshots of how C60 carbon molecules react to extremely short pulses of intense infrared light.

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Nano drops a million times smaller than a teardrop explodes 19th century theory

Droplets emanating from a molecular 'nano-tap' would behave very differently from those from a household tap 1 million times larger — researchers at the University of Warwick have found. This is potentially crucial step for a number of emerging nano technologies, e.g., manufacture of nano-sized drug particles, lab-on-chip devices for in situ diagnostics, and 3D printers capable of nanoscale resol

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Infection biology: What makes Helicobacter so adaptable?

The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. Ludwig-Maximilians-Universitaet Munich microbiologists have identified an enzyme that plays a vital role in the flexible control of global gene expression in the species.

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Nanotechnology enables engineers to weld previously un-weldable aluminum alloy

Engineers at the UCLA Samueli School of Engineering are using nanotechnology to weld the alloy, known as AA 7075, which has been almost impossible to weld together using the technique commonly used to assemble body panels or engine parts.

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DNA methylation GrimAge strongly predicts lifespan and healthspan

When it comes to predicting lifespan, GrimAge is 18 percent more accurate than calendar age and 14 percent better than previously described epigenetic biomarkers. With regards to predicting time to coronary heart disease, GrimAge is 61 percent more accurate than chronological age and 46 percent better than previously reported epigenetic biomarkers. In spite of this significant enhancement however,

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Scientists gain new insight on triggers for preterm birth

A group of scientists led by Ramkumar Menon at The University of Texas Medical Branch at Galveston have gained new insight on a poorly-understood key player in the timing of labor and delivery. This new information brings scientists closer to being able to prevent preterm births. This study is in Scientific Reports.

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New gel for liver cell culture on microchips

Scientists at Linköping University, Sweden, have developed a new method to produce hydrated materials, hydrogels, that have properties similar to the natural environment of cells in the body. They describe in an article in Biofabrication how to adapt the material to the various requirements of difficult-to-culture cell types, and to produce organ-like structures on a microchip.

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High cadence cycling offers no benefit to amateurs, finds new study

A new study published today in the International Journal of Sports Medicine has found that exercise efficiency decreases in recreational cyclists when they pedal very hard, incorporating more revolutions per minute.

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Cross-species cancer comparison uncovers new drug targets, study reveals

Mucosal melanoma arises in non-skin locations such as sinuses, nasal passages and mouth. The research team sequenced the genomes of mucosal melanoma tumours from 46 humans, 65 dogs and 28 horses and discovered a handful of genes that were commonly mutated in all species.These genetic similarities point to the drivers of the disease — key information that will lead to using biologically relevant d

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Insurance rules make it harder to treat opioid use disorder

Insurance industry cost-control measures may be worsening the nation's opioid epidemic by limiting access to a key medication that treats addiction, according to a research letter published today in the Journal of the American Medical Association. Despite the medical profession's growing acceptance of the need for medications for addiction treatment that give hope to people suffering with opioid u

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Hyperbolic metamaterials enable nanoscale 'fingerprinting'

Hyperbolic metamaterials are artificially made structures that can be formed by depositing alternating thin layers of a conductor such as silver or graphene onto a substrate. One of their special abilities is supporting the propagation of a very narrow light beam. This narrow beam can then be used to 'fingerprint' and obtain spatial and material information about nanometer-scale objects — allowin

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USPSTF recommendation statement on interventions to prevent depression during pregnancy, after childbirth

The US Preventive Services Task Force (USPSTF) recommends clinicians provide counseling interventions to pregnant and postpartum women at increased risk of depression or refer patients to those services.

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Intervening in glial cells protects neurons in Parkinson's model

Stressed dopaminergic neurons call nearby glial cells for help. Those calls can over-activate the glial cells resulting in a cascade of inflammatory signaling that, over time, contributes to neuronal degradation. Working in two fly models of Parkinson's, researchers characterized a novel mechanism that orchestrates this cascade and demonstrated that disrupting it protects neurons as they age. The

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Mom's reward: Female Galapagos seabird has a shorter lifespan than males

The male Nazca booby, a large seabird of the Galápagos Islands, often outlives the domineering female of the species, according to new research from Wake Forest University published today in the Journal of Animal Ecology. Why? It's a story of rotating sex partners, the cost of being a parent and how the body falls apart in old age.

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New tarantula species from Angola distinct with a one-of-a-kind 'horn' on its back

A new to science species of tarantula with a peculiar horn-like protuberance sticking out of its back was recently identified from Angola, a largely underexplored country located at the intersection of several Afrotropical ecoregions.

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New Bionic Heart Charges Wirelessly Inside Patient’s Chest

Beating Heart Failure More than 50 years ago , a doctor implanted the first mechanical heart pump, also known as a ventricular assist device (VAD), in the chest of a patient whose heart couldn’t pump blood on its own. Since then, the devices have saved countless lives, including that of Ismail Tursunov. The 24-year-old man was experiencing end-stage heart failure when doctors in Kazakhstan implan

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Dansk læge sender 300 røde roser til kritisk norsk journalist

Journalist fra Dagens Medisin Norge opfattede 300 roser samt et kort med lumre undertoner leveret til privatadressen som en trussel. Dansk læge erkender forsendelsen og undskylder.

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Scientists make the track their lab to improve the performance of racing drivers

A new concept that, for the first time, collects biomechanical data from drivers and riders while on the track could give racing teams a new dimension to optimise their performance.

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Study investigates when and why bribes buy influence, and what lessens their effectiveness

A new study from Carnegie Mellon University suggests that greed, and not the willingness to return the favor, is the main reason people give in to bribery. But the research also finds there are times when the almighty buck can be ignored and effects of a bribe can be lessened.

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How air pollution exposure may lead to autism

Researchers have previously linked air pollution exposure—particularly traffic-related air pollution—to a higher risk of autism, but new research may have an answer for how that relationship works. In an earlier study, researchers discovered that mice exposed to very unhealthy levels of diesel exhaust, or particulate matter, during pregnancy and early in development displayed behavioral alteratio

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Brexit as much due to resistance to supranationalism as immigration

The UK referendum vote to leave the European Union (EU) may have had as much to do with people's distrust of international organisations as it did fear of immigration.

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Walking simulation games signal a new literary genre

Research from the University of Kent has revealed that walking simulations are blurring the boundaries of different art forms to create a new literary genre.

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LGBTQ teens are over-represented in foster care

Lesbian, gay, bisexual, transgender, and questioning teens are more likely to end up in foster care and experience substance abuse or mental health issues while living in the child welfare system, research finds. For the new study in Pediatrics , researchers looked at 593,241 youths living in California in grades 6-12. Less than 1 percent of the sample lived foster care or unstable housing. But m

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Earth's Magnetic Field Booms Like a Drum, But No One Can Hear It

And for the first time, physicists have recorded the wild drum beats rippling from the magnetic poles.

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Investing in antibiotics critical to saving lives during pandemic influenza outbreaks

Researchers have developed a mathematical framework to estimate the value of investing in developing and conserving an antibiotic to mitigate the burden of bacterial infections caused by resistant Staphylococcus aureus during a pandemic influenza outbreak.

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The Analysts Recording Your Screen Say It’s for Your Own Good

Apple issued a warning to developers last week after a Techcrunch report revealed a number of banking and travel companies contracted with an analytics firm, Glassbox, to record customers’ screens as they used their apps. Apple’s app store requires developers to obtain consent and inform users if they’re being recorded. Glassbox never required its customers to alert users to screen recordings. “W

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Fossilized Tubes Point to Super-Ancient Mobile Organisms

If the structures identified in a 2.1-billion-year-old rock are really signs of burrowing organisms, it would push back the earliest known mobile organisms by 1.5 billion years.

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Ancient spider fossils, surprisingly preserved in rock, reveal reflective eyes

A new paper in the Journal of Systematic Palaeontology, coauthored by a KU researcher, describes fossil spiders found in an area of Korean shale called the Lower Cretaceous Jinju Formation.

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Streetcars don't guarantee heightened development activity, study finds

Development outcomes along streetcar corridors can't be entirely attributed to the presence of the streetcar, researchers found. Streetcar investment is commonly accompanied with a healthy incentive package, for example.

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The search for the holy grail: Promising strategies for slowing, stopping, or reversing Parkinson's disease

Understanding of the processes involved in Parkinson's disease (PD) degeneration has vastly improved over the last 20 years. In this insightful review, published in the special supplement to the Journal of Parkinson's Disease, experts consider which of the existing strategies to slow down or stop the degenerative processes of PD are most likely to be successful over the next 20 years.

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Dams can mimic the free flow of rivers, but risks must be managed

In recent decades, humans have built many dams. These are designed to regulate flow for irrigation, hydropower and water supply. Most major rivers in the world are dammed.

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This Scary Map Shows How Climate Change Will Transform Your City

Click on your city, and the map will pinpoint a modern analog city that matches what your climate may be in 2080. The results are startling.

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How the Brain Creates a Timeline of the Past

It began about a decade ago at Syracuse University, with a set of equations scrawled on a blackboard. Marc Howard , a cognitive neuroscientist now at Boston University, and Karthik Shankar , who was then one of his postdoctoral students, wanted to figure out a mathematical model of time processing: a neurologically computable function for representing the past, like a mental canvas onto which the

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New AI toolkit is the 'scientist that never sleeps'

Researchers have developed a new AI-driven platform that can analyse how pathogens infect our cells with the precision of a trained biologist.

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World faces 'catastrophic' risks over insect extinction

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Gory, freaky, cool: Marine snail venom could improve insulin for diabetic patients

Although moderately mobile, marine cone snails have perfected several strategies to capture prey. Some fish-hunting species release venom into the surrounding water. Within the plume of toxic venom, the fish succumbs to fast-acting insulin that renders it immobile. As the fish flounders, the snail emerges from its shell to swallow the pacified victim whole.

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New AI toolkit is the 'scientist that never sleeps'

Researchers have developed a new AI-driven platform that can analyse how pathogens infect our cells with the precision of a trained biologist.

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Genocide: why a focus on prevention would produce a better outcome

One hundred and forty nine countries have signed the Convention on the Prevention and Punishment of the Crime of Genocide of 1948. These signatories present themselves as the authorities who are committed to and entrusted with preventing genocide.

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The DIY Divorce

I belong to a private Facebook group of middle-aged women who share stories of age discrimination, infidelity, sexual dysfunction, depression, hot flashes, melanomas, empty nests, ailing parents, and other baubles of midlife mirth. Every so often, a new post will appear, announcing the rupture of a decades-long marriage, the wound of it so new and gaping you can practically taste the blood drippi

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A Duplicitous Minister?

In a ‘Breakfast’ interview with Fran Kelly on ABC Radio National, the Australian Minister for Energy, Angus Taylor, made a number of statements which are either wrong or misleading. A record of the interview is available here . 1. The Minister claims that a ‘significant investment of $15 billion is being made in renewables’. This is an understatement of over $11 billion. Fig. 1., shows that as at

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Why noise is bad for your health — and what you can do about it | Mathias Basner

Silence is a rare commodity these days. There's traffic, construction, air-conditioning, your neighbor's lawnmower … and all this unwanted sound can have a surprising impact on your health, says noise researcher Mathias Basner. Discover the science behind how noise affects your health and sleep — and how you can get more of the benefits of the sound of silence.

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How a Love of Flowers Helped Charles Darwin Validate Natural Selection

Though his voyage to the Galapagos and his work with finches dominate the narrative of the famed naturalist, he was, at heart, a botanist

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Gory, freaky, cool: Marine snail venom could improve insulin for diabetic patients

Although moderately mobile, marine cone snails have perfected several strategies to capture prey. Some fish-hunting species release venom into the surrounding water. Within the plume of toxic venom, the fish succumbs to fast-acting insulin that renders it immobile. As the fish flounders, the snail emerges from its shell to swallow the pacified victim whole.

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Upgrading ALICE: What's in store for the next two years?

With massive red doors weighing 350 tonnes each, it takes more than uttering "open sesame" to open the ALICE detector. Behind the doors lie the inner workings of a unique detector built to study the conditions of matter moments after the birth of the Universe, conditions which are recreated in the LHC.

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Scientists provide new insight on gene mutations associated with autism

A novel investigation into the impacts of neuronal mutations on autism-related characteristics in humans has been described in the open-access journal eLife.

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Accelerated risk of mobility loss for people aged 60+ tied to excess weight/inactivity

The combination of excess weight/obesity and an inactive lifestyle represents a powerful joint risk factor for developing mobility loss after age 60, according to a new study.

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New tarantula species from Angola distinct with a one-of-a-kind 'horn' on its back

A new to science species of tarantula with a peculiar horn-like protuberance sticking out of its back was recently identified in central Angola, a largely underexplored country located at the intersection of several Afrotropical ecoregions. Collected as part of the National Geographic Okavango Wilderness Project, the new arachnid is described in the open-access journal African Invertebrates.

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Mom's reward: Female Galápagos seabird has a shorter lifespan than males

The male Nazca booby, a large seabird of the Galápagos Islands, often outlives the domineering female of the species, according to new research from Wake Forest University published today in the Journal of Animal Ecology. Why? It's a story of rotating sex partners, the cost of being a parent and how the body falls apart in old age.

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International applications to US graduate programmes are still declining

International applications to US graduate programmes are still declining International applications to US graduate programmes are still declining, Published online: 12 February 2019; doi:10.1038/d41586-019-00566-3 Fewer students are applying from India, Europe, Mexico and Middle Eastern nations.

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A.I. analyzed 50,000 living rooms around the world

Artificial intelligence analyzed design elements in Airbnb photos of 50,000 living rooms around the world. The results show that people tend to follow cultural trends when they decorate their interiors. In the United States, where the researchers had economic data from the US Census, they find that people across socioeconomic lines put similar efforts into interior decoration. “We were interested

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Selfies to self-diagnosis: Algorithm 'amps up' smartphones to diagnose disease

Smartphones aren't just for selfies anymore. A novel cell phone imaging algorithm can now analyze assays typically evaluated via spectroscopy, a powerful device used in scientific research. Researchers analyzed more than 10,000 images and found that their method consistently outperformed existing algorithms under a wide range of operating field conditions. This technique reduces the need for bulky

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Trilobites: Birds of a Feather May Stick Together, but This Bird’s Foot Got Stuck in Amber

Known as “Ugly Foot” or “Hobbit Foot,” researchers say the feathered specimen offers long-sought clues to the evolutionary path of birds.

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How antibiotics used in factory farming destroy our microbiomes

More and more research nowadays links good gut flora to several health benefits, such as the inhibition of Alzheimer's to a fast metabolism. Since we're over prescribed antibiotics, and because much of the meat we consume comes from animals that were fed antibiotics, we are destroying much of the good bacteria, and often at the risk — because of our diets — of replenishing them. Through calorie a

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Green New Deal proposal includes free higher education and fair pay

The Green New Deal is an ambitious plan to remake the US energy sector and fight climate change, but it’s bundled with progressive social goals that may stop it passing

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What makes Helicobacter so adaptable?

The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. LMU microbiologists have identified an enzyme that plays a vital role in the flexible control of global gene expression in the species.

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Transformation through light

Laser physicists have taken snapshots of how C60 carbon molecules react to extremely short pulses of intense infrared light.

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Data science is a growing field. Here's how to train people to do it

The world is inundated with data. There's a virtual tsunami of data moving around the globe, renewing itself daily. Take just the global financial markets. They generate vast amounts of data – share prices, commodity prices, indices, option and futures prices, to name just a few.

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Is AI a special ingredient to help make food taste better? IBM and McCormick think so

Sure, we're accustomed to artificial flavors influencing how our food tastes, but artificial intelligence getting baked in now?

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Marine life typically thrives in the tropics – so why do whales prefer the poles?

Life in the sea isn't easy. Talk to most people about the ocean and they are likely to imagine a tropical scene with a stretch of golden sand and warm, clear water. The reality is often quite different – the marine environment can be a surprisingly cold place.

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Pinnacle Engines develops efficient, low-emission gasoline engine using supercomputing

A more efficient car engine? That's the goal. An opposed-piston engine is more efficient than a traditional internal combustion engine. Pinnacle Engines is developing a multi-cylinder gasoline engine for automotive use. The team enhanced the engine's reciprocating sleeve-valve system, thanks to a Department of Energy supercomputer. The result? An engine with better combustion and reduced pollutant

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What makes Helicobacter so adaptable?

The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. LMU microbiologists have identified an enzyme that plays a vital role in the flexible control of global gene expression in the species.

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Marine life typically thrives in the tropics – so why do whales prefer the poles?

Life in the sea isn't easy. Talk to most people about the ocean and they are likely to imagine a tropical scene with a stretch of golden sand and warm, clear water. The reality is often quite different – the marine environment can be a surprisingly cold place.

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Vagthund: Trods dieselgate-stramninger oser EU's biler stadig for meget

Strammere lovgivning skulle forhindre emmissions-snyd efter dieselgate-skandalen og forbedre luftkvaliteten, men effekten er ikke så stor som håbet, konkluderer Den Europæisk Revisionsret.

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Därför är det lättare att vara HBTQ-person idag

Det har blivit enklare att vara gay och lesbisk. På 80-talet var acceptansen för homosexuella fem procent – sett till hela världen. Nu har den siffran vuxit till tjugo procent, enligt den regelbundna attitydundersökningen World Value Survey. Homosexuellas rätt att gifta sig sprider sig stadigt till allt fler länder och när samkönade äktenskap väl har införts verkar de vara ohotade. Rättvisa och i

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A Nobel Prize–Worthy Idea: What Is Chirped Pulse Amplification?

How does the laser technology that earned the 2018 Nobel Prize in Physics come into our everyday lives? — Read more on ScientificAmerican.com

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Trouble on the surface begins with a wave of tiny bubbles

An air bubble breakup that may compromise the performance of droplet-derived coatings has been uncovered by a team led by Sigurdur Thoroddsen and his Ph.D. student Kenneth Langley at KAUST.

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We've discovered the world's largest drum – and it's in space

Universities in the US have long wrangled over who owns the world's largest drum. Unsubstantiated claims to the title have included the "Purdue Big Bass Drum" and "Big Bertha", which interestingly was named after the German World War I cannon and ended up becoming radioactive during the Manhattan Project.

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Poor employment in tourism threatens sustainability

A new study in tourism employment finds that many jobs are failing to provide dignity in employment. The tourism sector, which accounts for nearly 10 per cent of global employment, risks undermining rather than contributing to the United Nation's Sustainable Development Goals, according to three academics from the University of Surrey.

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Scientists discover that charcoal traps ammonia pollution

Cornell University scientists Rachel Hestrin and Johannes Lehmann, along with collaborators from Canada and Australia, have shown that charcoal can mop up large quantities of nitrogen from the air pollutant ammonia, resulting in a potential slow-release fertilizer with more nitrogen than most animal manures or other natural soil amendments. The results were published Friday in Nature Communication

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Young children who express suicidal ideation understand death better than their peers

Four- to six-year-old children who express suicidal thoughts and behaviors have a better understanding of what it means to die than the majority of their peers, reports a new study.

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Phase transition dynamics in two-dimensional materials

Scientists have discovered the mechanism involved when transition metal dichalcogenides on metallic substrates transform from the semiconducting 1H-phase to the quasi-metallic 1T'-phase.

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Face transplant surgery can improve speech in victims of severe face trauma

A new case study finds that face transplant surgery in patients who have experienced severe facial trauma can improve speech production.

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How Viagra puts a brake on a master growth regulator to treat heart disease

When normal cells grow, divide or do any job in the body, they do so in response to a whole slew of internal sensors that measure nutrients and energy supply, and environmental cues that inform what happens outside the cell.

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Why does bribery work?

A new study from Carnegie Mellon University suggests that greed, and not the willingness to return the favor, is the main reason people give in to bribery. But the research also finds there are times when the almighty buck can be ignored and effects of a bribe can be lessened.

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Consciousness rests on the brain's ability to sustain rich dynamics of neural activity

Consciousness, from the moment we go to sleep until we wake up, seems to come and go every day. Consciousness can be temporarily abolished by pharmacological agents or more permanently by brain injury. Each of these departures from conscious wakefulness brings about different changes in brain function, behaviour and in the brain's neurochemistry. However, they all share a common feature: the lack

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In solar system's symphony, Earth's magnetic field drops the beat

Inside Earth's magnetic bubble, scientists have long been listening in on space sounds created by various electromagnetic waves, and now they've found one that booms like a drum.

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Brexit as much due to resistance to supranationalism as immigration

The UK referendum vote to leave the European Union (EU) may have had as much to do with people's distrust of international organisations as it did fear of immigration.

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Some primary care doctors not prepared to help with cancer treatment decisions

Research has shown patients are discussing initial cancer treatment options with their primary care doctors. And now a new study finds that a significant number of these physicians report notable gaps in their knowledge of cancer treatment options.

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How to pay top executives if you want them to be innovative

When pay dispersion is perceived as linked to an executive's individual performance (as in variable pay), it's considered legitimate and may promote knowledge-sharing and cooperation among top executives. On the contrary, when pay dispersion is not perceived to depend on individual contribution (as in fixed pay), it ignites a demotivating process of social comparison, detrimental to knowledge shar

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Improving geothermal HVAC systems with mathematics

Sustainable heating, ventilation, and air conditioning systems, such as those that harness low-enthalpy geothermal energy, are needed to reduce collective energy use and mitigate the continued effects of a warming climate. In a paper publishing on Feb. 12 in the SIAM Journal on Applied Mathematics, Miguel Hermanns and Santiago Ibáñez use asymptotic expansion techniques to study the harmonic therma

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Novel technique accurately assesses cardiovascular risks

A new noninvasive technique for imaging the carotid artery offers advantages over other imaging methods and could provide an earlier, more accurate assessment of cardiovascular disease risk, according to a new study.

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Chemists develop a new eco-friendly material for waste water purification

RUDN chemists have developed a hybrid nanocatalyst for quick removal of stable organic dyes from wastewater. This catalyst does not require additional aggressive solvents. The results of the study were published in Inorganic Chemistry.

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Study finds indebtedness among low income households worsened under government austerity measures

A paper recently published in New Political Economy by a team of academics led by Hulya Dagdeviren, Professor of Economic Development, University of Hertfordshire, concludes that austerity measures over the past decade, especially the cuts in welfare and local government budgets, accompanied by a range of disciplinary measures, pushed the very poor into various forms of debt by severely limiting t

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Community Neuroscience: How to Write About Neuroscience

Want to learn the do’s and dont’s of communicating neuroscience? Tune in to the fifth episode of Community Neuroscience, and find out! We interview Kayt Sukel , an accomplished science writer whose essays and articles have appeared in The Atlantic Monthly, New Scientist, The Washington Post, Pacific Standard, National Geographic, Science, Memory & Cognition, and more. She has written a number of

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Scientists research impact of oil rig spills on fish

University of Manchester scientists are at the forefront of the fight to protect cold water fish from the effects of crude oil spills from offshore oil rigs.

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New method of fertilizer production can better suit the needs of farms in Africa and around the globe

Nitrogen, phosphorous, and potassium are the three elements that support the productivity of all plants used for agriculture, and are the constituents of commercial fertilizers that farmers use throughout the world.

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FADL melder sig ind i den politiske debat med nyt udspil

Fremtidens læger skal uddannes som basislæger, KBU’en skal forlænges, der skal oprettes flere hoveduddannelsesstillinger og alle studerende skal forbi almen praksis. Det foreslår FADL i sit første politiske udspil.

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Publisher Correction: Genomic insights into the 2016–2017 cholera epidemic in Yemen

Publisher Correction: Genomic insights into the 2016–2017 cholera epidemic in Yemen Publisher Correction: Genomic insights into the 2016–2017 cholera epidemic in Yemen, Published online: 12 February 2019; doi:10.1038/s41586-019-0966-0 Publisher Correction: Genomic insights into the 2016–2017 cholera epidemic in Yemen

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Author Correction: HER kinase inhibition in patients with HER2- and HER3-mutant cancers

Author Correction: HER kinase inhibition in patients with HER2- and HER3-mutant cancers Author Correction: HER kinase inhibition in patients with HER2- and HER3-mutant cancers, Published online: 12 February 2019; doi:10.1038/s41586-019-0974-0 Author Correction: HER kinase inhibition in patients with HER2- and HER3-mutant cancers

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Scientists research impact of oil rig spills on fish

University of Manchester scientists are at the forefront of the fight to protect cold water fish from the effects of crude oil spills from offshore oil rigs.

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Three evolution researchers talk about Charles Darwin, evolution on other planets and mass extinction on Earth

Celebrations are held on the 12th of February each year to commemorate the birthday of Charles Darwin, the 19th-century British naturalist, who achieved major insights into the process of evolution thereby completely revolutionising traditional concepts of life on earth and human's position in it. For Diethard Tautz and Paul Rainey of the Max Planck Institute for Evolutionary Biology in Plön and R

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Three evolution researchers talk about Charles Darwin, evolution on other planets and mass extinction on Earth

Celebrations are held on the 12th of February each year to commemorate the birthday of Charles Darwin, the 19th-century British naturalist, who achieved major insights into the process of evolution thereby completely revolutionising traditional concepts of life on earth and human's position in it. For Diethard Tautz and Paul Rainey of the Max Planck Institute for Evolutionary Biology in Plön and R

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Using artificial intelligence to foil online dating scams

Dating apps and websites could soon use computing algorithms that 'think' like humans to pinpoint fake profiles designed to con victims out of thousands of pounds.

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At the rim: Mods to nanotubes help filter salt from seawater

As the global population continues to climb, the demand for drinkable freshwater is likewise rising. One potential solution to the shortages now threatening one-third of the world's people involves removing salt from seawater and saline aquifers, which collectively represent 98 percent of humanity's water supply.

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Engineered miniature kidneys come of age

A research team has now removed a major barrier for the use of kidney organoids as a tool to model kidney diseases, test drug toxicities and eventually for the creation of organ replacements, the lack of a pervasive blood vessel system (vasculature). The team solved this problem with a powerful new approach that exposes stem cell-derived kidney organoids to fluidic shear stress and thus enables th

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”Det kan vara kört absolut, men jag har hopp om att vi är tillräckligt smarta”

Klimatet genom historien, stigande havsnivåer och hur vi konsumerar var några av huvudämnena under SVT:s klimatchatt igår. Intresset var stort med över 500 inkomna frågor.

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Greenland may have another massive crater hiding under its ice

There may be yet another large crater buried beneath Greenland’s ice sheet. But it’s probably not related to the first one found last year.

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Universal basic income experiment made people happier but not more likely to get a job

Finland's Social Insurance Institution (FSII) has published the results of an income experiment it carried out for two years to learn more about ways to reduce unemployment. They report that their experiment showed that giving unemployed people a no-strings-attached guaranteed income instead of an unemployment allowance made them happier and less stressed—but it did not make them any more or less

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James Clerk Maxwell Telescope discovers flare 10 billion times more powerful than those on the sun

The Hawaii-based James Clerk Maxwell Telescope (JCMT) has discovered a stellar flare 10 billion times more powerful than the Sun's solar flares, a history-making discovery that could unlock decades-old questions about the origin of our own Sun and planets, giving insight into how these celestial bodies were born.

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Scientists discover that charcoal traps ammonia pollution

Cornell University scientists Rachel Hestrin and Johannes Lehmann, along with collaborators from Canada and Australia, have shown that charcoal can mop up large quantities of nitrogen from the air pollutant ammonia, resulting in a potential slow-release fertilizer with more nitrogen than most animal manures or other natural soil amendments. The results were published Friday in Nature Communication

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Molecular-weight polymer selection by one-dimensional confinement

Researchers at Kanazawa University report in Nature Communications that a crystal of molecules known as pillar[5]arenes can form a host–guest compound with poly(ethylene oxides) polymers. The effect can be used to select polymers with different molecular weights and end groups.

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Archaeologists discover ancient workshop in Egypt's Sinai

Egypt says archaeologists have uncovered an ancient workshop used to build and repair ships that dates back to the Ptolemaic era (332 B.C.-30 B.C.) in the Sinai Peninsula.

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Improving geothermal HVAC systems with mathematics

Extreme weather events, water shortages, and other consequences of climate change have challenged—and compromised—energy infrastructure around the world. Increased energy consumption is threatening the longevity of a dependable energy supply, and significant reductions to collective energy usage are necessary to mitigate the continued effects of a warming climate. Most energy sources require fuel

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A Photographer Re-Creates the Snapshots in Old Family Albums

Rie Yamada collects vintage photo albums and re-stages the images—with herself as all the subjects.

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Robert Theobald & Alan Watts : Early proponents of guaranteed basic income

Economist Robert Theobald coined the team basic living guarantee in the 1960s. He believed that we were going to suffer problems because of an overabundance of resources. Philosopher Alan Watts spoke about the possibility for an economic utopia through a universal basic income. The perceived threat of labor-ending automation, a stratified elite class and increasingly complexified occupations has

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A new mouse model may unlock the secrets of type I diabetes

Finding new treatments or a cure for type I diabetes has been elusive in part because scientists have not had a reliable animal model that mimics the full scope of human type I diabetes. A research team has now developed a humanized mouse model that spontaneously develops Type I diabetes and the full range of complications experienced by diabetes patients. That allows study of the disease and its

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Selfies to self-diagnosis: Algorithm 'amps up' smartphones to diagnose disease

Smartphones aren't just for selfies anymore. A novel cell phone imaging algorithm can now analyze assays typically evaluated via spectroscopy, a powerful device used in scientific research. Researchers analyzed more than 10,000 images and found that their method consistently outperformed existing algorithms under a wide range of operating field conditions. This technique reduces the need for bulky

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Another early-onset Alzheimer's gene mutation found, and traced back to Africa

For some of us, they carry the bright blue of our grandfather's eyes. For others they result in the characteristic cleft chin or the familial tendency toward color blindness. But in some families, the genetic mutations handed down from generation to generation aren't as benign. And for one family in particular, the mutation results in early-onset Alzheimer's disease.

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Ice volume calculated anew

Researchers have provided a new estimate for the glacier ice volume all around the world, excluding the Greenland and Antarctic ice sheets. Their conclusion: previous calculations overestimated the volume of the glaciers in High Mountain Asia.

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Simple and low-cost crack-healing of ceramic-based composites

A team of researchers has demonstrated that cracks induced in composites consisting of alumina ceramics and titanium could be healed at room temperature, a world-first. This ceramic healing method permits crack-healing even in a state in which a device is mounted on a ceramic package at a low cost and without using complicated heat treatment processes that require significant amounts of energy.

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A Fleshy New Humanoid Sketches You, Mimics Your Facial Expressions

Robot Artists Today’s robots can run , talk , and even learn . But can they become artists? UK engineers from robotics company Engineered Arts are building a robot called “Ai-Da,” which will eventually be able to draw and even paint, Reuters reports . Thanks to a pencil attached to her robotic arm, Ai-Da is capable of sketching what she can see with her robotic eyes, which relay information to he

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Cancer comparison across species highlights new drug targets

Cancer genes in mucosal melanoma, a rare and poorly understood subtype of melanoma, have been compared in humans, dogs and horses for the first time by scientists at the Wellcome Sanger Institute and their collaborators. Researchers sequenced the genomes of the same cancer across different species to pinpoint key cancer genes. The results give insights into how cancer evolves across the tree of li

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Walking simulation games signal a new literary genre

Walking simulation games signal a new literary genre Research from the University of Kent has revealed that walking simulations are blurring the boundaries of different art forms to create a new literary genre.Walking simulations — video games where there are no winners and no one is shot at or killed — have become increasingly popular in the last few years.

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New AI toolkit is the 'scientist that never sleeps'

Researchers have developed a new AI-driven platform that can analyze how pathogens infect our cells with the precision of a trained biologist.

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IQWiG supported professional societies in the development of new S3 guideline

Commissioned by the Federal Ministry of Health, the Institute searched for studies on vaginal ('natural') birth and assessed them. The guideline group appreciates the high quality of the reports.

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NTU, MIT and Russian scientists develop AI to predict and engineer material properties

Scientists from NTU Singapore, MIT and the Skolkovo Institute of Science and Technology in Russia, have developed a machine learning approach that can predict changes to the properties of materials from straining the material.

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Young children who express suicidal ideation understand death better than their peers

Four- to six-year-old children who express suicidal thoughts and behaviors have a better understanding of what it means to die than the majority of their peers, reports a study recently published in the Journal of the American Academy of Child and Adolescent Psychiatry.

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TDC efter overvågnings-kritik: Vores logning blev kastebold mellem to uenige myndigheder

Det er uholdbart, at TDC's masselogning kom i klemme mellem Datatilsynet og Erhvervsstyrelsen, mener koncerndirektør.

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New Study Suggests You Can Learn While You Sleep

As a chronic insomniac, I have a trick to lure me to sleep without drugs: podcasts. Every night before bed, I queue up a list of podcasts lengthy enough to last me the night. And sometimes, their contents bleed through into my dreams. Over the years, I’ve dreamed of microbiomes, politics, pop culture, molecular gastronomy—and intriguingly, sometimes the things I heard while sleeping seem to stick

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Upskirting is now illegal in England and Wales

Upskirting is now a criminal offense in England and Wales after campaigners lobbied for years for the UK government to outlaw the practice. The new legislation means that individuals …

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Maya bones bring a lost civilization to life

Maya bones bring a lost civilization to life Maya bones bring a lost civilization to life, Published online: 12 February 2019; doi:10.1038/d41586-019-00517-y Trained in both medicine and archaeology, Vera Tiesler has revealed how the human body was deeply woven into the religion, tradition and politics of the Maya world.

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A Reading List for Ralph Northam

In the years before he became Virginia’s governor, Ralph Northam apparently chose not to read books in which blackface was present. “I used just a little bit of shoe polish to put under my—or on my—cheeks,” he said about the day he impersonated Michael Jackson in blackface. “I look back now and regret that I did not understand the harmful legacy of an action like that.” Now, as governor, Northam

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Investing in antibiotics critical to saving lives during pandemic influenza outbreaks

In a new study published in the journal Health Economics, researchers at CDDEP, the University of Strathclyde in Scotland, and Wageningen University in the Netherlands developed a mathematical framework to estimate the value of investing in developing and conserving an antibiotic to mitigate the burden of bacterial infections caused by resistant Staphylococcus aureus during a pandemic influenza ou

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Obstructive sleep apnea linked to inflammation, organ dysfunction

In the study, 'Obstructive Sleep Apnea and Inflammation: Proof of Concept Based on Two Illustrative Cytokines,' published recently in the International Journal of Molecular Sciences, researchers examined the link between obstructive sleep apnea syndrome (OSAS) and inflammation and the ensuing damage caused to organs. They concluded that OSAS promotes a persistent low-intensity inflammatory state.

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Up to 15 percent of children have sleep apnea, yet 90 percent go undiagnosed

Children who have behavior problems or are suspected to have ADHD might actually be suffering from a chronic lack of restorative sleep. Symptoms include snoring, restless sleep, excessive sleepiness, teeth grinding and jaw clenching, migraines, bedwetting, and irritability. Sleep apnea and related conditions can cause lasting damage to brain development during crucial years. As a result, children

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Face transplant surgery can improve speech in victims of severe face trauma

A new case study out of New York University's Steinhardt School of Culture, Education, and Human Development finds that face transplant surgery in patients who have experienced severe facial trauma can improve speech production.

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Hovedstaden har positive erfaringer med Avastin til udvalgte hjernetumor­patienter

Midtjylland har sagt stop til at behandle tilbagefald af hjernetumorer med Avastin. Erfaringer fra Hovedstaden viser dog, at nøje udvalgte hjernetumorpatienter med tilbagefald har ‘overbevisende effekt’ af behandlingen.

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The best indoor plants for people who kill plants

DIY Plants that will survive your dark apartment and forgetful nature. If you’re interested in getting plants but are wavering on your decision because you have a self-proclaimed rotten thumb, take heart. .

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Obstructive sleep apnea linked to inflammation, organ dysfunction

Voyagers no longer embark in search of the storied Fountain of Youth, but the quest for longevity is still very much alive for researchers. Chronological age — the passing of time one spends on this planet — cannot be reversed, of course. However, biological age — one's health relative to that of one's peers — can be turned back. Healthy lifestyle habits contribute to "aging well," meaning one

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Gory, freaky, cool: Marine snail venom could improve insulin for diabetic patients

Researchers detailed the function of cone snail insulins, bringing them one step closer to developing a faster-acting insulin to treat diabetes.

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Direct-acting antivirals reduce risk of premature mortality and liver cancer for people with chronic hepatitis C, study finds

The first prospective, longitudinal study investigating treatment of chronic hepatitis C with direct-acting antivirals finds that the treatment is associated with reduced risk of mortality and liver cancer.

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Study finds upsurge in 'active surveillance' for low-risk prostate cancer

Many men with low-risk prostate cancer who most likely previously would have undergone immediate surgery or radiation are now adopting a more conservative 'active surveillance' strategy, according to a new study.

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Almost 2,000 unknown bacteria discovered in the human gut

Researchers have used computational methods to identify nearly 2,000 uncultured gut bacterial species. Study authors call for more data from South America, Africa and Asia, in order to achieve a more comprehensive blueprint of the human gut. Access to thousands of new gut bacterial genomes allows researchers to characterize the gut microbiota more accurately.

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Engineered miniature kidneys come of age

A research team has now removed a major barrier for the use of kidney organoids as a tool to model kidney diseases, test drug toxicities and eventually for the creation of organ replacements, the lack of a pervasive blood vessel system (vasculature). The team solved this problem with a powerful new approach that exposes stem cell-derived kidney organoids to fluidic shear stress and thus enables th

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NASA finds possible second impact crater under Greenland ice

A NASA glaciologist has discovered a possible second impact crater buried under more than a mile of ice in northwest Greenland.

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AI, 5G and the race to completely autonomous vehicles

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We just tried the new Google Maps AR feature for the first time

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Pæleorme gnasker sig gennem moler og skibsvrag i danske farvande

Små træædende pæleorme breder sig til havne og kyster i Danmark og Tyskland til stor gene for havnefolk og arkæologer. Årsagen er stigende temperaturer.

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Lysande framtid för plastljuskällor

Det finns potentiella användningsområden för ljus där det krävs flexibla och mångsidiga ljuskällor med stora lysande ytor och lysande mönster. – De unika ljuskällor vi jobbar med, som lite omständligt kallas för ljusemitterande elektrokemiska celler, är väl lämpade för att möta dessa krav och samtidigt kan tillverkningen hållas kostnadseffektiv och miljövänlig, säger Mattias Lindh, doktorand på I

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Förskolebarn behöver hjälp att ta till sig vetenskapligt innehåll

I förskolan behandlas ofta vetenskapligt innehåll med hjälp av bilder, modeller eller lek vilket ger barnen möjligheter att uppleva, upptäcka, uttrycka och lära med hela kroppen och alla sinnen. Men ofta görs detta utan att barnen får någon förklaring som kopplar ihop aktiviteten med det innehåll som står i fokus. Anneli Bergnell har i fyra delstudier studerat naturvetenskapliga illustration

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The U.S. Doesn’t Deserve the World Bank Presidency

During his time in office, President Donald Trump has named a climate-change skeptic and an energy lobbyist as the heads of the Environmental Protection Agency, a foreclosure profiteer to head Treasury, a low-wage employer to run the Labor Department, and a critic of public schools to manage the Department of Education. His energy secretary once argued that the department should be abolished, and

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Simple and low-cost crack-healing of ceramic-based composites

A team of researchers at Osaka University demonstrated that cracks induced in composites consisting of alumina ceramics and titanium could be healed at room temperature, a world-first. This ceramic healing method permits crack-healing even in a state in which a device is mounted on a ceramic package at a low cost and without using complicated heat treatment processes that require significant amoun

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Ice volume calculated anew

Researchers have provided a new estimate for the glacier ice volume all around the world, excluding the Greenland and Antarctic ice sheets. Their conclusion: previous calculations overestimated the volume of the glaciers in High Mountain Asia.

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Selfies to self-diagnosis: Algorithm 'amps up' smartphones to diagnose disease

Smartphones aren't just for selfies anymore. A novel cell phone imaging algorithm developed at FAU can now analyze assays typically evaluated via spectroscopy, a powerful device used in scientific research. Researchers analyzed more than 10,000 images and found that their method consistently outperformed existing algorithms under a wide range of operating field conditions. This technique reduces t

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A new mouse model may unlock the secrets of type I diabetes

Finding new treatments or a cure for type I diabetes has been elusive in part because scientists have not had a reliable animal model that mimics the full scope of human type I diabetes. A research team at The University of Toledo has developed a humanized mouse model that spontaneously develops Type I diabetes and the full range of complications experienced by diabetes patients. That allows study

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German researchers discover how sleep can fight infection

Researchers in Germany have discovered why sleep can sometimes be the best medicine. Sleep improves the potential ability of some of the body's immune cells to attach to their targets, according to a new study that will be published Feb. 12 in the Journal of Experimental Medicine. The study, led by researchers at the University of Tübingen, helps explain how sleep can fight off an infection, where

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New research suggests a simple blood test could improve the early detection of lung cancer

New research led by scientists at the MRC Toxicology Unit suggests that by analysing levels of DNA in the blood, the early detection of lung cancer could be improved. The study, published in the journal Disease Models and Mechanisms, found that in preliminary tests using mice, a blood test could measure the circulating levels of DNA in the blood which cancer cells shed as they grow and multiply, a

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'Improbable things happen'

For some of us, they carry the bright blue of our grandfather's eyes. For others they result in the characteristic cleft chin or the familial tendency toward color blindness.But in some families, the genetic mutations handed down from generation to generation aren't as benign. And for one family in particular, the mutation results in early-onset Alzheimer's disease.

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Network driving emergency healthcare research

The Emergency Medicine Foundation — Australia has successfully piloted a Research Support Network to foster research in more than 30 Queensland public hospital emergency departments. By providing a skills-based infrastructure, the Foundation stimulated in a significant increase in research activity among emergency medicine clinicians. It was also able to engage rural and regional sites in researc

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Courage a double-edged sword for economic success

Modern economies need courageous, entrepreneurial individuals to thrive yet the same qualities can bring greater risks according to a world-first study. QUT's Associate Professor Martin Obschonka joined forces with researchers from Germany's University of Mannheim and the University of Cambridge in the UK to study data on courage from more than 390,000 Americans. The project was a collaboration wi

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Questions in quantum computing: How to move electrons with light

To design future quantum technologies, scientists pinpoint how microwaves interact with matter.

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Researchers present new findings on postpartum racial disparities and cardiovascular disease

Black women are more likely to be readmitted to the hospital after giving birth. Could text messages prevent readmission and decrease disparities in maternal mortality?

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Phase transition dynamics in two-dimensional materials

Scientists from National University of Singapore have discovered the mechanism involved when transition metal dichalcogenides on metallic substrates transform from the semiconducting 1H-phase to the quasi-metallic 1T'-phase.

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How to classify high blood pressure in pregnancy?

The American Heart Association (AHA) and the American College of Cardiology (ACC) changed their guidance to lower the threshold criteria for hypertension in adults. The American College of Obstetricians and Gynecologists, however, has different criteria. A new study looks at which set of guidelines is most appropriate.

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Researchers examine postpartum hospital readmissions for women with psychiatric conditions

Unlike postpartum readmissions for medical or obstetric complications, psychiatric readmissions were least likely to occur in the first 10 days after discharge. Instead, psychiatric readmissions take place later in the postpartum period.

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More than a courier

New research reveals that parts of the neuron are far more complex than once thought.

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Montmorency tart cherry juice helped lower blood pressure and LDL 'bad' cholesterol

Montmorency tart cherry juice helped lower systolic blood pressure and LDL or "bad" cholesterol in older adults by reducing certain biomarkers of inflammation and oxidative stress in older adults, according to a new study published in Nutrients.

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Did we evolve to pick our phones over our partners?

Our evolutionary history may explain why humans are so drawn to their smartphones, even when the devices take us out of the moment in our close relationships. In a recent study by the Pew Research Center, nearly 50 percent of adults reported they “couldn’t live without” their phones. “The draw or pull of a smartphone is connected to very old modules in the brain that were critical to our survival

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Motorola's Moto G7 line aims for budget phone shoppers with three new phones

A new phone doesn't need to cost you several hundred dollars.

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Retired astronaut Mark Kelly, husband of Gabby Giffords, to run for Senate

Kelly, 54, bids for Democratic nomination in election to determine who fills the last two years of John McCain’s term The retired astronaut Mark Kelly announced on Tuesday he is running to finish John McCain’s final term in the Senate. Related: 'Inhuman' wall of razor wire on Arizona-Mexico border sparks outcry Continue reading…

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Prehistoric Sailors May Be Responsible for Stonehenge, Other Megaliths

Megaliths across Europe might have a common origin in Northwestern France

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This robot artist will draw sketches of humans

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The Encroachment of AI Into Finance

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The Real Reason Tech Struggles With Algorithmic Bias

Opinion: Humans train the machine-learning and AI systems at Facebook, Google, and Twitter to filter out bias. The problem: they don't know what they're looking for.

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The Xiaomi M365 Scooter Can Be Hacked to Speed Up or Stop

A hacker can accelerate Xiaomi M365 scooter—or hit the breaks—while a rider is on it.

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From the archive

From the archive From the archive, Published online: 12 February 2019; doi:10.1038/d41586-019-00531-0 How Nature reported a key step towards test-tube babies in 1969, and strange damage to a German shell in 1919.

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Three secrets of survival in science advice

Three secrets of survival in science advice Three secrets of survival in science advice, Published online: 12 February 2019; doi:10.1038/d41586-019-00518-x Be impartial, humble and good value, urge Chris Tyler and Karen Akerlof.

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The physical forces of cells in action

The detection of physical forces is one of the most complex challenges facing science. Considered to play a decisive role in many biological processes, the chemical tools to visualize the physical forces in action do not exist. But today, researchers have developed probes inspired by lobster cooking, they enable to enter into cells. For the first time, physical forces can be imaged live inside the

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Queen Elizabeth Prize for Engineering: GPS pioneers lauded

Four Americans are celebrated for their roles in developing the sat-nav Global Positioning System.

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Marine scientists find toxic bacteria on microplastics retrieved from tropical waters

A field survey conducted by a team of marine scientists from the National University of Singapore (NUS) has uncovered toxic bacteria living on the surfaces of microplastics, which are pieces of plastic smaller than five millimetres in size, collected from the coastal areas of Singapore. These bacteria are capable of causing coral bleaching, and triggering wound infections in humans.

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New SpaceX Raptor engine beats the chamber pressure of Russia's RD-180 engine, according to Elon Musk

2019 has been shaping up to be an interesting year for SpaceX and its founder, Elon Musk. After completing work on the miniaturized version of the Starship (Starship Alpha or "Starship hopper") over the holidays, SpaceX moved ahead with the test-firing of its new Raptor engine in late January/early February. In accordance with Musk's vision, these engines will give the Starship the necessary thrus

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Musk Says Tickets to Mars Could Cost Just $500,000

Musk cautions that his ballpark estimate is highly dependent on volume, though. The post Musk Says Tickets to Mars Could Cost Just $500,000 appeared first on ExtremeTech .

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Skeleton of Teen Girl Found Buried Next to Mysterious Pyramid in Egypt

The 13-year-old was buried next to a partially collapsed pyramid dating back 4,600 years.

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Photos: Teen's Skeleton Buried Next to Pyramid in Egypt

Archaeologists have discovered the skeleton of a girl who was around 13 years of age when she died. Here's a look at the remains, the cemetery and the mysterious pyramid near where she was buried.

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Organotin poisoning may cause obesity, medics say

RUDN medics report that exposure to organotin compounds may cause metabolic disturbance and therefore lead to obesity. Being aware of the mechanisms of such exposure, doctors can neutralize the effect of the toxins. The work was published in the Journal of Inorganic Biochemistry.

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Biochemists report a way to stop the immortality of cancer cells with oligonucleotides

RUDN biochemists found a way to reduce the activity of telomerase (the enzyme of cell immortality) 10-fold. The discovery could lead to new antitumor drugs and give a better understanding of how the activity of the enzyme can be controlled. The results of the study were published in the journal Biochemical and Biophysical Research Communications.

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Why young people in South Korea are staying single despite efforts to spark dating

Recent reports about a sex recession among young Americans aside, the concept of dating and mating is reasonably engrained in daily life in the West. In sharp contrast, in South Korea, 40 per cent of people in their 20s and 30s appear to have quit dating altogether.

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Study takes aim at biased AI facial-recognition technology

A study by Deb Raji, a fourth-year student in the University of Toronto's Faculty of Applied Science & Engineering, and researchers at the Massachusetts Institute of Technology is underscoring the racial and gender biases found in facial-recognition services.

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Reddit study shows how growth, aging affect online communities

Through studying groups on the website Reddit, researchers at The University of Alabama found as online groups grow and age, discussion concentrates among fewer contributors and retention of new contributors becomes harder.

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Organotin poisoning may cause obesity, medics say

RUDN medics report that exposure to organotin compounds may cause metabolic disturbance and therefore lead to obesity. Being aware of the mechanisms of such exposure, doctors can neutralize the effect of the toxins. The work was published in the Journal of Inorganic Biochemistry.

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Erica: Man-Made, documentary on the most lifelike humanoid robot

submitted by /u/dominiquec [link] [comments]

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What 50 principal investigators taught me about my failure to land tenure

What 50 principal investigators taught me about my failure to land tenure What 50 principal investigators taught me about my failure to land tenure, Published online: 12 February 2019; doi:10.1038/d41586-019-00560-9 Bela Z. Schmidt’s quest to understand an all-too-familiar career setback can be distilled into eight pieces of advice.

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Sundhedsminister: Udenlandske læger skal kunne dansk

Sundhedsminister sender lovforslag i høring, der præciserer, at det er arbejdsgiverens ansvar, at læger har de rette sproglige kompetencer til den opgave, de skal løse.

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Researchers engineer more efficient Cas12a variants

A team of researchers from Massachusetts General Hospital, Harvard Medical School and MIT has engineered Cas12a variants that are able to target a wider range of protospacer adjacent motifs (PAMs). In their paper published in the journal Nature Biotechnology, the group describes the variants they engineered and how they fared when compared against more traditional Cas12a nucleases (enzymes that ar

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Longest-ever eDNA study offers important insights into ocean health

Tiny genetic 'breadcrumbs' left behind by marine organisms offer unprecedented insights into ocean biodiversity and how it changes over time and in response to our changing climate, new research at Curtin University, in collaboration with CSIRO, has revealed.

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Xbox Live could soon be coming to iOS, Android and the Nintendo Switch

Playing games between an Xbox and Nintendo Switch may soon expand beyond "Fortnite," "Minecraft" and "Rocket League."

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Researchers engineer more efficient Cas12a variants

A team of researchers from Massachusetts General Hospital, Harvard Medical School and MIT has engineered Cas12a variants that are able to target a wider range of protospacer adjacent motifs (PAMs). In their paper published in the journal Nature Biotechnology, the group describes the variants they engineered and how they fared when compared against more traditional Cas12a nucleases (enzymes that ar

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Biochemists report a way to stop the immortality of cancer cells with oligonucleotides

RUDN biochemists found a way to reduce the activity of telomerase (the enzyme of cell immortality) 10-fold. The discovery could lead to new antitumor drugs and give a better understanding of how the activity of the enzyme can be controlled. The results of the study were published in the journal Biochemical and Biophysical Research Communications.

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Longest-ever eDNA study offers important insights into ocean health

Tiny genetic 'breadcrumbs' left behind by marine organisms offer unprecedented insights into ocean biodiversity and how it changes over time and in response to our changing climate, new research at Curtin University, in collaboration with CSIRO, has revealed.

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Slowing climate change could reverse drying in the subtropics

As the planet warms, subtropical regions of the Southern Hemisphere, including parts of southern Australia and southern Africa, are drying. These trends include major drought events such as Cape Town's "Day Zero" in 2018.

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Scientists develop tungsten-based hydrogen detectors

A team of physicists from Immanuel Kant Baltic Federal University together with their colleagues from National Research Nuclear University MEPhI (NRNU MEPhI) has developed a tungsten oxide-based detector of hydrogen in gas mixes. They manufactured thin tungsten oxide films with various additives and compared their characteristics. One of the film detectors demonstrated a 100-fold increase in sensi

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Earth's magnetic shield booms like a drum when hit by impulses

The Earth's magnetic shield booms like a drum when it is hit by strong impulses, according to new research.

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The physical forces of cells in action

The detection of physical forces is one of the most complex challenges facing science. Considered to play a decisive role in many biological processes, the chemical tools to visualize the physical forces in action do not exist. But today, researchers have developed probes inspired by lobster cooking, they enable to enter into cells. For the first time, physical forces can be imaged live inside the

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What can early adulthood tell us about midlife identity?

A recent study indicates that personality style in young adulthood anticipates identity formation later in life.

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Research will help urban planners prioritize bike lanes

A new virtual tool could help planners choose the best places to install bikes lanes in cities. The data-based tool builds on previous research that validated the safety benefits of bike lanes for cyclists and motorists.

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Investigating cell stress for better health — and better beer

Human beings are not the only ones who suffer from stress — even microorganisms can be affected. Now, researchers have devised a new method to study how single biological cells react to stressful situations. Understanding these responses could help develop more effective drugs for serious diseases. As well as that, the research could even help to brew better beer.

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More is better when coordinating with others

Researchers have demonstrated that physical coordination is more beneficial in larger groups.

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Tracking HIV's ever-evolving genome in effort to prioritize public health resources

Using HIV genetic data, researchers discovered that transgender women in Los Angeles are at higher risk of being in an HIV transmission network than men who have sex with men. In addition, cisgender men in these clusters should be considered at higher risk for HIV than previously thought.

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New deep sea animal discoveries warrant expanded protections in Costa Rican waters

Scientists surveyed deep-sea seamounts outside Isla del Coco UNESCO World Heritage site revealing coral communities with surprising diversity.

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Arctic sea ice loss in the past linked to abrupt climate events

A new study on ice cores shows that reductions in sea ice in the Arctic in the period between 30-100,000 years ago led to major climate events. During this period, Greenland temperatures rose by as much as 16 degrees Celsius.

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Climate change is killing off Earth's little creatures

Climate change gets blamed for a lot of things these days: inundating small islands, fueling catastrophic fires, amping-up hurricanes and smashing Arctic sea ice.

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Climate change is killing off Earth's little creatures

Climate change gets blamed for a lot of things these days: inundating small islands, fueling catastrophic fires, amping-up hurricanes and smashing Arctic sea ice.

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3D-print: Lys skaber figurer i væske

PLUS. Amerikanske forskere vil skabe lynhurtige 3D-print ved at belyse et flydende materiale i en roterende beholder. Danske 3D-eksperter er dog skeptiske.

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Kepler's final image

On October 30th, 2018, after nine years of faithful service, the Kepler Space Telescope was officially retired. With nearly 4000 candidates and 2,662 confirmed exoplanets to its credit, no other telescope has managed to teach us more about the worlds that exist beyond our solar system. In the coming years, multiple next-generation telescopes will be deployed that will attempt to build on the found

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The FDA and the Dietary Supplements

I’ve been complaining for years on this blog about the “dietary supplement” industry, which exists in its present form thanks to Sen. Orrin Hatch. That’s the 1994 “Dietary Supplement Health and Education Act”, which like many a federal bill has a name that is somewhat detached from reality. I would suggest the “Sell Any Damn Pill You Want Act” , with the proviso that you include words “dietary su

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MU69, previously presumed a space snowman, is instead a pair of cosmic pancakes

Space Earth isn't flat, but this strange world might be. Instead of two spherical blobs, it’s really more like two flattened rocks that came together at one point and got stuck, like pancakes cooked side by side…

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Preliminary Results Point to Success of In Vivo Gene Editing

Two studies show signs that the introduced DNA is functioning, but it's too early to know if patients actually benefit.

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Discovery of the oldest evidence of mobility on Earth

Scientists have uncovered the oldest fossilized traces of motility. Whereas previous remnants were dated to 570 million years ago, this new evidence is 2.1 billion years old. They were discovered in a fossil deposit in Gabon, where the oldest multicellular organisms have already been found.

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Nearly half of adults with heart disease can't afford their medical bills

More than 45 percent of non-elderly adults with atherosclerotic cardiovascular disease (ASCVD) report financial hardship due to the associated medical bills. Worse still, about one in five report being unable to pay those medical bills at all, said the researchers.

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Learning a second alphabet for a first language

A part of the brain that maps letters to sounds can acquire a second, visually distinct alphabet for the same language, according to a study of English speakers. The research challenges theoretical constraints on the range of visual forms available to represent written language.

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Connection between home energy efficiency and respiratory health in low-income homes

A new study finds people living in drafty homes in low-income, urban communities are at a higher risk of respiratory health issues.

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Cities turn to desalination for water security, but at what cost?

Removing salts and other impurities from water is really difficult. For thousands of years people, including Aristotle, tried to make fresh water from sea water. In the 21st century, advances in desalination technology mean water authorities in Australia and worldwide can supply bountiful fresh water at the flick of a switch.

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Gory, freaky, cool: Marine snail venom could improve insulin for diabetic patients

Researchers at University of Utah Health detailed the function of cone snail insulins, bringing them one step closer to developing a faster-acting insulin to treat diabetes.

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A Computer Spotted a Turtle Hiding Out in a Cloud of 'Quantum Fireworks'

Scientists couldn't find the pattern in these strange clouds of quantum fireworks. So they enlisted a computer, and it noticed a hidden turtle.

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The Andromeda galaxy, as you’ve never seen it before

State-of-the-art sky-surveying camera produces exciting early results.

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‘Dynamic pricing’ can train us to shop smarter

Dynamic pricing can generate unintended consequences by changing the behavior of customers, according to a new paper. When your online retail platform clears billions of transactions a year, what’s the harm in testing different prices for the same products on a relative handful of your customers? You might find a way to maximize revenue by increasing sales volume on your lower-priced products, ri

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CTA prototype telescope, the Schwarzschild-Couder Telescope, achieves first light

Less than a week after its inauguration on 17 January 2019, the prototype Schwarzschild-Couder Telescope (pSCT), a prototype telescope proposed for the Cherenkov Telescope Array (CTA), successfully detected its first Cherenkov light on January 23 at the Fred Lawrence Whipple Observatory in Arizona. A dual-mirrored Medium-Sized Telescope, the SCT is proposed to cover the middle of CTA's energy rang

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Simple and low-cost crack-healing of ceramic-based composites

A team of researchers at Osaka University demonstrated that cracks induced in composites consisting of alumina ( Al2O3) ceramics and titanium (Ti) as dispersed phase could be healed at room temperature, a world first. This ceramic healing method permits crack-healing even in a state in which ceramic parts are mounted on devices at a low cost and without using complicated high-temperature heat trea

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Takara Bio: iPS-Cell Derived Hepatocytes

Reliably sourcing hepatocytes just got easier!

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Sorry, Sandra Bullock: A Fire Extinguisher Is a Lousy Thruster

In the movie *Gravity*, Sandra Bullock uses a fire extinguisher to maneuver in space. Controlling it is much, much harder than it looks.

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A New Lab Is Brewing Microbes to Create Makeup and Medicines

At Culture Biosciences, rows of bioreactors are brewing yeast and bacteria so synthetic biology startups can produce their foods, biofuels, and medicines faster.

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‘The most villainous act in the history of human civilisation.’ Michael E Mann speaks out

The renowned US climate scientist and Tyler Prize winner talks exclusively to Samantha Page for Cosmos .

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Ultima Thule latest: less Star Wars, more Star Trek

Images from New Horizons reveal unexpected aspects of the Kuiper Belt object. Richard A Lovett reports.

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Dark flight and debris: lessons from the end of China’s space station

When Tiangong-1 crashed into the ocean last year, lots of scientists were watching. Richard A Lovett reports.

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Polio returns to Papua New Guinea

Low vax rates blamed for a slew of new cases in recent months. Andrew Masterson reports.

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Reflections from a Nobel winner: Scientists need time to make discoveries

In 2018, Donna Strickland was awarded the Nobel Prize in Physics. Here she argues that scientists must be free to be curious, without the pressure to produce results.

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Surrounded by low achievers—High on positive emotions?

The phenomenon tremendously important for a person's self-perception is referred to as the "Big Fish, Little Pond Effect" (BFLPE). A fish perceives itself as big when it swims in a comparatively small pond. This means: If you find yourself in a relatively low-performing environment, your perception of your own abilities increases. Your "self-concept" is enhanced, because you are the big fish among

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Why Russia is planning to briefly disconnect from the internet

Russia hopes to find out how smoothly it could transition to a self-contained internet in the event foreign actors tried to disconnect the nation from the rest of the internet. The experiment will reportedly occur before April 1. Russia's attempts to bolster its local internet infrastructure come in the wake of other nations accusing it of executing cyber attacks. None Russia plans to briefly dis

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Image of the Day: Nor Any Drop to Drink

Sea snakes wait in thirst for “lenses” of freshwater forming on the surface of the ocean after a heavy rain.

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Violent drug cartels stifle Mexican science

Violent drug cartels stifle Mexican science Violent drug cartels stifle Mexican science, Published online: 12 February 2019; doi:10.1038/d41586-019-00458-6 Abandoned projects and delayed research have become common problems as security issues crop up across the country.

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A peek at living room decor suggests how decorations vary around the world

People around the world paint their walls different colors, buy plants to spruce up their interiors and engage in a variety of other beautifying techniques to personalize their homes, which inspired a team of researchers to study about 50,000 living rooms across the globe.

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Scientists develop probes designed to reveal the physical forces inside living cells; a world first

The detection of physical forces is one of the most complex challenges facing science. Although Newton solved the problem of gravity long ago, imaging the physical forces that act within living cells remains one of the main mysteries of current biology. Considered to play a decisive role in many biological processes, the chemical tools to visualize the physical forces in action do not exist. But t

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Study examines how 'data in the wild' is used in diverse school district

For several decades, federal policymakers have pushed for education in America to be a more scientific endeavor. Researchers have sought to improve all aspects of education, but little attention has been paid to the experiences of educators putting research into practice. By studying one school district's adoption of a comprehensive reform initiative, a recent study from the University of Kansas f

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Human enhancement: Is it good for society?

Human enhancement technologies are opening up tremendous new possibilities. But they're also raising important questions about what it means to be human, and what is good or bad for our individual and collective well-being. These technologies are currently geared toward upgrading or restoring physical and psychological abilities for medical purposes. An application is surfacing, however, that is d

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Kidney Organoid Breakthrough

We are on the cusp of several technologies that promise to transform medicine – genetic manipulation, brain-machine interface, and stem cell therapies among them. One of the hopes for stem cells is that we will be able to grow from them entire replacement organs. Imagine that you have kidney failure, and face years of dialysis with the hope of finding a kidney donor, so you can exchange that dial

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This 2.1-Billion-Year-Old Fossil May Be Evidence of Earliest Moving Life-Form

About 2.1 billion years ago, a blob-like creature inched along on an early Earth. As the organism moved, it carved out tunnels, which may be the earliest evidence of a moving critter on the planet.

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Basis of efficient blue-green light harvesting and photoprotection in diatoms revealed

Diatoms are abundant photosynthetic organisms in aquatic environments; they contribute 20 percent of global primary productivity. Their fucoxanthin (Fx) chlorophyll (Chl) a/c-binding proteins (FCPs) have exceptional light harvesting and photoprotection capabilities. However, the structure of the FCP proteins and arrangement of pigments within them remain unknown.

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Investigating cell stress for better health—and better beer

Human beings are not the only ones who suffer from stress—even microorganisms become stressed out. Now, researchers from Chalmers University of Technology, Sweden, have devised a new method to study how single biological cells react to stressful situations. Understanding these responses could lead to more effective drugs for serious diseases. Additionally, the research could even help to brew bett

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Checking in on the Health and Vigor of the Chesapeake Bay

As clean-up milestones are registered by a recent assessment of the nation’s largest estuary, a Smithsonian geographer drops in on the region

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X-ray photoelectron spectroscopy of hydrogen and helium

For the first time scientists measured the vibrational structure of hydrogen and helium atoms by X-rays. The results disprove the misconception that it's impossible to obtain X-ray photoelectron spectroscopy (XPS) spectra of hydrogen and helium, the two lightest elements of the Periodic Table. This was thought to be the case due to low probabilities of electron ejection from these elements induced

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Next-generation optics in just two minutes of cooking time

Optical circuits are set to revolutionize the performance of many devices. Not only are they 10 to 100 times faster than electronic circuits, but they also consume a lot less power. Within these circuits, light waves are controlled by extremely thin surfaces called metasurfaces that concentrate the waves and guide them as needed. The metasurfaces contain regularly spaced nanoparticles that can mod

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Basis of efficient blue-green light harvesting and photoprotection in diatoms revealed

Diatoms are abundant photosynthetic organisms in aquatic environments; they contribute 20 percent of global primary productivity. Their fucoxanthin (Fx) chlorophyll (Chl) a/c-binding proteins (FCPs) have exceptional light harvesting and photoprotection capabilities. However, the structure of the FCP proteins and arrangement of pigments within them remain unknown.

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Weyl goes chiral

Quasiparticles that behave like massless fermions, known as Weyl fermions, have been at the center of a string of exciting findings in condensed matter physics in recent years. The group of physicist Sebastian Huber at ETH Zurich now reports experiments in which they got a handle on one of the defining properties of Weyl fermions—their chirality.

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Investigating cell stress for better health—and better beer

Human beings are not the only ones who suffer from stress—even microorganisms become stressed out. Now, researchers from Chalmers University of Technology, Sweden, have devised a new method to study how single biological cells react to stressful situations. Understanding these responses could lead to more effective drugs for serious diseases. Additionally, the research could even help to brew bett

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Scientists develop probes designed to reveal the physical forces inside living cells; a world first

The detection of physical forces is one of the most complex challenges facing science. Although Newton solved the problem of gravity long ago, imaging the physical forces that act within living cells remains one of the main mysteries of current biology. Considered to play a decisive role in many biological processes, the chemical tools to visualize the physical forces in action do not exist. But t

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Seven moral rules found all around the world

Anthropologists at the University of Oxford have discovered what they believe to be seven universal moral rules.

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Researchers show that tropical reefs can host coral or seaweed communities under the same conditions

Tropical reefs are vulnerable ecosystems, sensitive to a variety of environmental conditions and disturbances, which can change their composition from vibrant coral reefs to vast fields of seaweed or barren rubble.

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Researchers discover almost 2,000 new gut bacteria

Researchers have used a novel method to identify almost 2,000 unknown gut bacteria. Their findings also highlight a need to study more diverse samples.

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The new Picasso? Meet Ai-Da the robot artist

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Looking for love online may impact how humans evolve

Anybody looking for a Valentine's Day date in cyberspace might want to consider this prediction from an evolutionary biologist: Online dating could affect how humans evolve in the future.

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Scientists build the smallest optical frequency comb to-date

Optical frequency combs are laser sources whose spectrum consists of a series of discrete, equally spaced frequency lines that can be used for precise measurements. In the last two decades, they have become a major tool for applications such as precise distance measurement, spectroscopy, and telecommunications.

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Phase transition dynamics in two-dimensional materials

Scientists from National University of Singapore have discovered the mechanism involved when transition metal dichalcogenides on metallic substrates transform from the semiconducting 1H-phase to the quasi-metallic 1T'-phase.

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Questions in quantum computing—how to move electrons with light

Electronics rely on the movement of negatively-charged electrons. Physicists strive to understand the forces that push these particles into motion, with the goal of harnessing their power in new technologies. Quantum computers, for instance, employ a fleet of precisely controlled electrons to take on goliath computational tasks. Recently, researchers at the Okinawa Institute of Science and Technol

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Cultivate an 'ambidextrous' mindset for entrepreneurial success

New research shows entrepreneurs who have the greatest success in raising money for their startup have a key personality trait in common – they have an 'ambidextrous' mindset.

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Looking for love online may impact how humans evolve

Anybody looking for a Valentine's Day date in cyberspace might want to consider this prediction from an evolutionary biologist: Online dating could affect how humans evolve in the future.

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Russia Will ‘Unplug’ From Internet to Test Cyberdefenses, Censorship

The goal of the experiment is to provide feedback and gather insight on how the Russian national intranet would perform if severed from the main internet backbone. The post Russia Will ‘Unplug’ From Internet to Test Cyberdefenses, Censorship appeared first on ExtremeTech .

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Building a better fuel cell begins with surface chemistry

Fuel cells powered by electrocatalytic reactions have the potential to eliminate pollution caused by burning fossil fuels, if they could be made more efficient. Key to higher efficiency are the chemical reactions at the surfaces of the materials involved. An international team of scientists peered deep into the molecular reactions of ethanol on gold surfaces in alkaline environments typically seen

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Sprint sues AT&T over the company's use of '5G E,' claims false advertising

AT&T's calling its latest 4G LTE network "5G E" isn't just drawing the ire of tech media and fans. It's now drawing fire from Sprint in the form of a lawsuit.

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Study: How cells and tissues maintain their shape

Scientists have long pondered how the body's tissues maintain their stiffness in the face of growth, injury, and other forces. In a new study, Yale researchers have described this mysterious process, which is key to healthy cell and tissue function.

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Courage a double-edged sword for economic success

Modern economies need courageous, bold and entrepreneurial individuals to thrive yet the same qualities can bring greater risks according to a world-first study from an international research team.

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Study: How cells and tissues maintain their shape

Scientists have long pondered how the body's tissues maintain their stiffness in the face of growth, injury, and other forces. In a new study, Yale researchers have described this mysterious process, which is key to healthy cell and tissue function.

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Ice volume calculated anew

Researchers have provided a new estimate for the glacier ice volume all around the world, excluding the Greenland and Antarctic ice sheets. Their conclusion: previous calculations overestimated the volume of the glaciers in High Mountain Asia.

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The unintended consequences of tinkering with online prices

When your online retail platform clears billions of transactions a year, what's the harm in testing different prices for the same products on a relative handful of your customers? You might find a way to maximize revenue by increasing sales volume on your lower-priced products, right? Or, you might lock down sales on a product that your consumers were on the fence about.

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Astronomers Traverse the Globe to Shadow "Lucky Stars"

A surge in occultation science is allowing astronomers to study the sun’s asteroids, planets and moons like never before — Read more on ScientificAmerican.com

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The Obama Portraits Have Had a Pilgrimage Effect

In April 2018, the artist Wendy MacNaughton posted a picture titled Dispatch From DC on Instagram. It was a clever ink-and-watercolor drawing showing Rhonda, a security guard at the National Portrait Gallery, next to the newly unveiled portrait of Barack Obama by Kehinde Wiley. In a hand-printed caption, Rhonda is quoted recounting how an elderly lady had gotten on her knees and prayed in front o

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Cashing In on a Warming Arctic

PORTLAND, Maine—A less icy Arctic is coming, and generally speaking, that’s not a good thing . Climate change is warming this region twice as fast as the global average , threatening wildlife and indigenous communities. Melting permafrost in Greenland and the Arctic tundra is releasing vast amounts of methane, a potent climate-altering gas. But some see an Arctic with navigable seas in the summer

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The Future of Psychiatry Is Digital. That’s a Good Thing.

People often ask me if I think technology will soon replace psychiatrists. That’s unlikely to happen. But one day, patients may tap technology to get better care. And that’s good news — if we have the government policies and provider practices in place to ensure that the technology is used thoughtfully.

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Tyske myndigheder vidste intet om Hamborg-ulykke før dødsulykken på Storebælt

Danmark fik intet at vide om tysk togulykke fra 2014, der lignede Storebæltsulykken. Måske fordi den tyske havarikommission aldrig informerede de øvrige tyske myndigheder.

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Intellektet viktigt för överlevnad vid Parkinson

– Resultaten överraskar. Det är en tydlig skillnad i dödlighet för patienter med olika grad av kognitiv nedsättning. Det krävs mer forskning för att se vad som orsakar skillnaden och om den kan ge en nyckel till nya behandlingar, säger David Bäckström, doktorand vid Institutionen för farmakologi och klinisk neurovetenskap vid Umeå universitet. I sin avhandling har David Bäckström studerat 182 per

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Så gör en stressad cell – mätning banar väg för nya läkemedel gott öl

Det är inte bara vi människor som påverkas av stress. Alla levande organismer kan uppleva stress när de utsätts för krävande utmaningar. Celler och mikroorganismer har komplicerade system för att anpassa sig till nya förhållanden. Att förutse hur enskilda celler reagerar på olika förändringar är därför en svår uppgift. Celler kan nämligen ändra sin inre struktur genom att ta upp eller avge olika

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Stonehenge mystery solved? Prehistoric French may have inspired it and other European megaliths

Although Stonehenge may be the most famous of Europe's megaliths, it's far from the only one: There are about 35,000 of these mysterious stone structures throughout the continent.

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'Disturbing' music influences us to take fewer financial risks, Israeli researchers find

A recent study examined the different ways fast/arousing and slow/calming music affects the ways people make financial decisions. The results show that people made safer investments while listening to fast/arousing music, a finding that might be explained by the fact that people tend to be more risk averse when their working memory becomes overloaded. Although everyone experiences music different

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Astronomers Traverse the Globe to Shadow "Lucky Stars"

A surge in occultation science is allowing astronomers to study the sun’s asteroids, planets and moons like never before — Read more on ScientificAmerican.com

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Fitbit launches new wearable, but your employer has to sign you up

Fitbit quietly introduced a new activity and sleep tracker, but, unlike the company's previous step counters, the wearable is available only from your health plan or employer.

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Trending: Need a Breath of Fresh Air? Hotels to the Rescue

More hotels are adding air purifiers and filters to their guest rooms, either because the outside air is prone to smoke or pollution, or because guests demand them for health reasons.

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World Record Egg: From a challenge to social media to a mental health campaign

The Instagram account @world_record_egg was originally designed as a fun way to challenge and question social media, its creators say. However, the account quickly morphed into an opportunity to focus on mental health positivity and to encourage people to speak up.

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Gmail strammer op og lukker API-adgang – uvist om SMTP og IMAP forsætter

It-giganten er bekymret for en persondataskandale, fordi tredjeparts apps får adgang til gmail brugernes email. Derfor strammes der nu voldsomt op på API-adgang.

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Odlar en mänsklig lever på ett chip

Celler som odlats på labb används bland annat under läkemedelsutveckling för att testa om nya substanser skadar cellerna. En teknik som utvecklas snabbt är att odla celler från mänskliga organ på små chip med mikrokanaler där cellerna växer och syre och näring tillförs, så kallade Organ-on-a-Chip. Forskare försöker ta fram allt mer komplexa modeller som efterliknar hur vävnad eller hela organ fun

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Stonehenge mystery solved? Prehistoric French may have inspired it and other European megaliths

Although Stonehenge may be the most famous of Europe's megaliths, it's far from the only one: There are about 35,000 of these mysterious stone structures throughout the continent.

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Amazon buys eero: What does it mean for the price of Wi-Fi routers?

Eero was the first company of note to solve Wi-Fi issues at home through what is known as "mesh" technology. On Monday came word that Amazon and eero will be meshing together, with the news that the e-commerce giant was acquiring the San Francisco startup, pending customary regulatory approvals.

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How antibiotics used in factory farming destroy our microbiomes

More and more research nowadays links good gut flora to several health benefits, such as the inhibition of Alzheimer's to a fast metabolism. Since we're over prescribed antibiotics, and because much of the meat we consume comes from animals that were fed antibiotics, we are destroying much of the good bacteria, and often at the risk — because of our diets — of replenishing them. Through calorie a

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AR Will Spark the Next Big Tech Platform—Call It Mirrorworld

We are building a 1-to-1 map of almost unimaginable scope. When it's complete, our physical reality will merge with the digital universe.

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The Afghan Government Is Missing From Afghanistan's Peace Process

Can a peace process work if it excludes the government of the country in conflict? We may be finding out. At present, there are two distinct efforts under way to bring peace in Afghanistan: In one, Zalmay Khalilzad, the State Department’s special representative for Afghanistan reconciliation, has held several discussions with Taliban leaders. In the other, a meeting in Moscow this month brought t

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What Ralph Northam’s Defenders Get Right—And Wrong

After Virginia Governor Ralph Northam apologized for appearing in a photograph that featured one person in blackface and another wearing a Ku Klux Klan robe and hood, I argued that he could best serve the public by resigning in a way that reaffirmed the hard-won stigma against white supremacy. Others calling for his resignation include Virginia Senators Mark Warner and Tim Kaine, Hillary Clinton,

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University of Texas lacks authority to revoke PhDs, judge rules

The University of Texas (UT) at Austin does not have the authority to revoke degrees, a Texas judge ruled yesterday in a case involving a chemist whom the university alleges committed misconduct. UT revoked Suvi Orr’s PhD in 2014, two years after the retraction of a paper that made up part of her thesis because, … Continue reading University of Texas lacks authority to revoke PhDs, judge rules

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Robots are becoming classroom tutors. But will they make the grade?

Educational robots show promise for helping kids in the classroom or at home, but researchers are still figuring out how these bots should behave.

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Niels taler med fremmede på gaden for at holde sin stammen i skak

Stammen kan være en ubetydelig talefejl, hvis man håndterer det tidligt nok, siger en ekspert.

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Danske forskeres projekter med i kampen om at blive EU-flagskibe

Den næste store europæiske forskningssatsning skal findes inden for batteriteknologi, medicin, energi, kunstig intelligens eller digitalisering af historien. Vinderprojekterne bliver EU-flagskibe og får en mia. euro, og danske forskere er med i flere konsortier.

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Rigsrevision med ny kritik af gældsinddrivelsen: 50 milliarder kroner kan ikke indrives

Der er nye og stadig alvorlige problemer med den offentlige gældsinddrivelse, lyder det fra Rigsrevisionen i delrapport.

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Stenåldersgravar visar hur folk spred sig över Europa

Det finns idag ungefär 35 000 megaliter – fornlämningar som är byggda av ett enda eller flera stenblock – kvar över hela Europa. De flesta kommer från Neolitikum (yngre stenåldern) och kopparåldern (mellan yngre stenåldern och bronsåldern) och är koncentrerade till kustnära områden. Frågan forskarna har ställt sig länge har varit om förekomsten av megalitgravar spreds över Europa från ett ursprun

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Nissan cuts forecast in first earnings since Ghosn arrest

Crisis-hit Japanese automaker Nissan slashed its full-year forecast Tuesday as nine-month net profit dropped 45 percent in the first earnings report since the stunning arrest of former chairman Carlos Ghosn.

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Integrating experimental and distribution data to predict future species patterns

Integrating experimental and distribution data to predict future species patterns Integrating experimental and distribution data to predict future species patterns, Published online: 12 February 2019; doi:10.1038/s41598-018-38416-3 Integrating experimental and distribution data to predict future species patterns

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Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira

Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira , Published online: 12 February 2019; doi:10.1038/s41598-018-37949-x Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for g

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Facile Fabrication of Size-Tunable Core/Shell Ferroelectric/Polymeric Nanoparticles with Tailorable Dielectric Properties via Organocatalyzed Atom Transfer Radical Polymerization Driven by Visible Light

Facile Fabrication of Size-Tunable Core/Shell Ferroelectric/Polymeric Nanoparticles with Tailorable Dielectric Properties via Organocatalyzed Atom Transfer Radical Polymerization Driven by Visible Light Facile Fabrication of Size-Tunable Core/Shell Ferroelectric/Polymeric Nanoparticles with Tailorable Dielectric Properties via Organocatalyzed Atom Transfer Radical Polymerization Driven by Visible

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Rab33a and Rab33ba mediate the outgrowth of forebrain commissural axons in the zebrafish brain

Rab33a and Rab33ba mediate the outgrowth of forebrain commissural axons in the zebrafish brain Rab33a and Rab33ba mediate the outgrowth of forebrain commissural axons in the zebrafish brain, Published online: 12 February 2019; doi:10.1038/s41598-018-38468-5 Rab33a and Rab33ba mediate the outgrowth of forebrain commissural axons in the zebrafish brain

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Permeability regain and aqueous phase migration during hydraulic fracturing shut-ins

Permeability regain and aqueous phase migration during hydraulic fracturing shut-ins Permeability regain and aqueous phase migration during hydraulic fracturing shut-ins, Published online: 12 February 2019; doi:10.1038/s41598-018-38211-0 Permeability regain and aqueous phase migration during hydraulic fracturing shut-ins

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PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma

PRSS3 /Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma PRSS3 /Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma, Published online: 12 February 2019; doi:10.1038/s41598-018-38362-0 PRSS3 /Me

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Investigating the Effects of Stove Emissions on Ocular and Cancer Cells

Investigating the Effects of Stove Emissions on Ocular and Cancer Cells Investigating the Effects of Stove Emissions on Ocular and Cancer Cells, Published online: 12 February 2019; doi:10.1038/s41598-019-38803-4 Investigating the Effects of Stove Emissions on Ocular and Cancer Cells

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A galling insect activates plant reproductive programs during gall development

A galling insect activates plant reproductive programs during gall development A galling insect activates plant reproductive programs during gall development, Published online: 12 February 2019; doi:10.1038/s41598-018-38475-6 A galling insect activates plant reproductive programs during gall development

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Blomman doftar olika på olika platser

– På ett ställe doftar de tallskog, på ett annat precis som jenkatuggummi, och lite längre söderut parfym, berättar Magne Friberg, lektor vid biologiska institutionen, Lunds universitet. I åtta år har han studerat blomdoften i 94 populationer av stenbräckesläktet Lithophragma på den amerikanska västkusten, tillsammans med forskare från University of California, Cornell University och University o

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Microsoft Launches LinkedIn Live, A New Corporate Video Streaming Service

Microsoft acquired LinkedIn over two and a half years ago, paying a whopping $26.2 billion in cash for the world's largest professional social network. It ranked as Microsoft CEO Satya Nadella's …

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A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP

A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP, Published online: 12 February 2019; doi:10.1038/s41467-019-08441-5 ATP has essential roles in cell signalling and energy homeostasis and biosensors to detect it have many potential applications. Here, the authors devel

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Whole-genome sequencing identifies ADGRG6 enhancer mutations and FRS2 duplications as angiogenesis-related drivers in bladder cancer

Whole-genome sequencing identifies ADGRG6 enhancer mutations and FRS2 duplications as angiogenesis-related drivers in bladder cancer Whole-genome sequencing identifies ADGRG6 enhancer mutations and FRS2 duplications as angiogenesis-related drivers in bladder cancer, Published online: 12 February 2019; doi:10.1038/s41467-019-08576-5 Bladder cancer is one of the most common and highly vascularized

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Biallelic mutations in valyl-tRNA synthetase gene VARS are associated with a progressive neurodevelopmental epileptic encephalopathy

Biallelic mutations in valyl-tRNA synthetase gene VARS are associated with a progressive neurodevelopmental epileptic encephalopathy Biallelic mutations in valyl-tRNA synthetase gene VARS are associated with a progressive neurodevelopmental epileptic encephalopathy, Published online: 12 February 2019; doi:10.1038/s41467-018-07067-3 Valyl-tRNA synthetase (VARS) charges valyl-tRNA with the amino ac

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Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes

Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes, Published online: 12 February 2019; doi:10.1038/s41467-019-08449-x Type-2 innate lymphoid cells (ILC2s) are an immune population secreting Th2 cytokines playing a role in t

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Controlling light in complex media beyond the acoustic diffraction-limit using the acousto-optic transmission matrix

Controlling light in complex media beyond the acoustic diffraction-limit using the acousto-optic transmission matrix Controlling light in complex media beyond the acoustic diffraction-limit using the acousto-optic transmission matrix, Published online: 12 February 2019; doi:10.1038/s41467-019-08583-6 Various techniques combine light and ultrasound to study the inside of strongly scattering sample

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Biallelic VARS variants cause developmental encephalopathy with microcephaly that is recapitulated in vars knockout zebrafish

Biallelic VARS variants cause developmental encephalopathy with microcephaly that is recapitulated in vars knockout zebrafish Biallelic VARS variants cause developmental encephalopathy with microcephaly that is recapitulated in vars knockout zebrafish, Published online: 12 February 2019; doi:10.1038/s41467-018-07953-w tRNAs are linked with their cognate amino acid by aminoacyl tRNA synthetases (A

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Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis

Pathogenic function of bystander-activated memory-like CD4 + T cells in autoimmune encephalomyelitis Pathogenic function of bystander-activated memory-like CD4 + T cells in autoimmune encephalomyelitis, Published online: 12 February 2019; doi:10.1038/s41467-019-08482-w T cells express specific T cell receptors (TCR) to recognise antigens and initiate adaptive immune responses. Here the authors sh

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Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer

Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer, Published online: 12 February 2019; doi:10.1038/s41467-019-08574-7 Loss of PIK3R1 in ovarian cancer is a common event, which provides opportunities for therapeutic intervention.

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Earth's magnetic shield booms like a drum when hit by impulses

The Earth's magnetic shield booms like a drum when it is hit by strong impulses, according to new research from Queen Mary University of London.

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IBM's AI debate computer loses to human champion

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A.I. Shows Promise as a Physician Assistant

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United Nations atlas maps risks from earthquakes worldwide

United Nations atlas maps risks from earthquakes worldwide United Nations atlas maps risks from earthquakes worldwide, Published online: 12 February 2019; doi:10.1038/d41586-019-00552-9 United Nations atlas maps risks from earthquakes worldwide

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South Africa: stop personal profit from publication payouts

South Africa: stop personal profit from publication payouts South Africa: stop personal profit from publication payouts, Published online: 12 February 2019; doi:10.1038/d41586-019-00548-5 South Africa: stop personal profit from publication payouts

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Stewpots and string: how scientists make do

Stewpots and string: how scientists make do Stewpots and string: how scientists make do, Published online: 12 February 2019; doi:10.1038/d41586-019-00522-1 Derek Lowe draws lessons for today from a history of scientists’ experimental hacks.

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US national academies offer tools for human rights in science

US national academies offer tools for human rights in science US national academies offer tools for human rights in science, Published online: 12 February 2019; doi:10.1038/d41586-019-00550-x US national academies offer tools for human rights in science

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Conservation charities top citation charts

Conservation charities top citation charts Conservation charities top citation charts, Published online: 12 February 2019; doi:10.1038/d41586-019-00549-4 Conservation charities top citation charts

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Find the switch for healthy artificial lighting

Find the switch for healthy artificial lighting Find the switch for healthy artificial lighting, Published online: 12 February 2019; doi:10.1038/d41586-019-00551-w Find the switch for healthy artificial lighting

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Fresh wave of cuts strikes Argentina’s science 18 years on

Fresh wave of cuts strikes Argentina’s science 18 years on Fresh wave of cuts strikes Argentina’s science 18 years on, Published online: 12 February 2019; doi:10.1038/d41586-019-00547-6 Fresh wave of cuts strikes Argentina’s science 18 years on

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