Rapid experimental evolution of reproductive isolation from a single natural population [Evolution]
Ecological speciation occurs when local adaptation generates reproductive isolation as a by-product of natural selection. Although ecological speciation is a fundamental source of diversification, the mechanistic link between natural selection and reproductive isolation remains poorly understood, especially in natural populations. Here, we show that experimental evolution of parasite body size…
5h
30% of Americans believe it's okay for businesses not to serve gay folks
A new poll by PPRI found that nearly a quarter of Americans say it's okay to not serve atheists on religious grounds. The pro-discrimination number was even higher regarding gays and lesbians. Bias against Jews, Muslims, and African Americans is also increasing. None Discrimination has long been an ugly human trait. Bias served an important role over the long course of evolution—"Is this friend o
21h
Affaldskampagner preller af: Roskilde Festivalens gæster sviner videre
Roskilde Festival har et affaldsproblem: Over 2000 ton skrald efterlades hvert år på festivalen. Ingen vil aftage de efterladte soveposer.
6h
Scientists weigh the balance of matter in galaxy clusters
A method of weighing the quantities of matter in galaxy clusters – the largest objects in our universe – has shown a balance between the amounts of hot gas, stars and other materials.
now
Using a common anticonvulsant to counteract inflammation
The interaction between a chromosomal protein called HMGB1 and a cellular receptor called RAGE is known to trigger inflammation. Researchers have now used computer software to analyze structural similarities among existing drugs, and discovered that the popular anticonvulsant drug papaverine blocks the binding of HMGB1 to RAGE. The researchers conclude that papaverine can potentially be used to tr
now
Measuring the laws of nature
One of the fundamental physical constants, the 'weak axial vector coupling constant' (gA), has now been measured with very high precision for the first time. It is needed to explain nuclear fusion in the sun, to understand the formation of elements shortly after the Big Bang, or to understand important experiments in particle physics. With the help of sophisticated neutron experiments, the value o
now
Mushrooms: Darker fruiting bodies in cold climates
The fly agaric with its red hat is perhaps the most evocative of the diverse and variously colored mushroom species. Hitherto, the purpose of these colors was shrouded in mystery. Researchers have now put together the first pieces of this puzzle.
now
Parasitology: On filaments and fountains
Microbiologists have shown that Toxoplasma gondii, the parasite that is responsible for toxoplasmosis, utilizes at least two modes of locomotion during its infection cycle.
now
An Arctic Fox's Epic Journey: Norway to Canada in 76 Days
The animal amazed researchers by trekking more than 2,175 miles across continents, including a stunning run across sea ice.
4min
Airport Facial Recognition, How Abusers Exploit Basic Apps, and More News
Catch up on the most important news from today in two minutes or less.
9min
Facebook Is Finally Fighting Its Pseudoscience "Miracle Cure" Content Problem
There's an entire spectrum of lies on social media. On one side, there's the generally inane: Pokémon was designed for Satanists or FCC Chairman Ajit Pai tried to date a porn star. And then there are lies that have the potential to literally kill. Falling into this latter category are the spammy "miracle cures" for everything from cancer to autism that spread like wildfire on sites like Facebook
33min
Tiny granules can help bring clean and abundant fusion power to Earth
submitted by /u/izumi3682 [link] [comments]
33min
Waymo is now allowed to transport passengers in its self-driving vehicles on California roads – TechCrunch
submitted by /u/izumi3682 [link] [comments]
33min
Redefining the limits of measurement accuracy
Scientists have introduced a method based on a non-classical state adapted to two measurement parameters at once. This will enable precision measurements of molecules which could reveal interactions between conventional and dark matter.
34min
High brightness mid-infrared laser expands horizon of spectroscopic analytical technique
Researchers have used an extremely bright mid-infrared laser to perform an analytical technique known as spectroscopic ellipsometry. The new approach captures high-resolution spectral information in less than a second and could offer new insights into quickly changing properties of a variety of samples from plastics to biological materials.
34min
Study reveals a short bout of exercise enhances brain function
Neuroscientists at Oregon Health & Science University, working with mice, have discovered that a short burst of exercise directly boosts the function of a gene that increases connections between neurons in the hippocampus, the region of the brain associated with learning and memory.
40min
Astronomers help wage war on cancer
Techniques developed by astronomers could help in the fight against breast and skin cancer. Charlie Jeynes at the University of Exeter will present his and Prof Tim Harries team's work today (July 3, 2019) at the RAS National Astronomy Meeting (NAM 2019) at the University of Lancaster.
40min
Tesla delivered a record 95,000 cars this spring
Tesla didn't have the greatest start to 2019, but it's looking rosier toward the middle of the year. The company set records for both production and deliveries in the second …
45min
The Big Evil Companies Are Right
You probably have not heard of the Retail Industry Leaders Association (RILA), but by its name could likely guess, correctly, that its a trade group representing the likes of Walmart, Target, …
45min
Atmosphere of midsize planet revealed by Hubble, Spitzer
Two NASA space telescopes have identified the detailed chemical 'fingerprint' of a planet between the sizes of Earth and Neptune. No planets like this can be found in our own solar system, but they are common around other stars.
46min
The neuroscience of autism: New clues for how condition begins
Scientists have uncovered details of a key cellular mechanism crucial for proper brain development. It involves a gene that, when mutated, had previously been linked to the development of autism.
46min
'Nothing Prepares You for the Inhumanity of It'
Haunting. Several U.S. lawmakers have used the word to describe what they saw during a visit to two Border Patrol processing centers in Texas on Monday, where they say they communicated with detained children through thick glass walls and met sobbing women who lacked access to running water. "Nothing prepares you for the inhumanity of it," Representative Madeleine Dean of Pennsylvania told me by
54min
Yellow Jacket 'Super Nests' the Size of Cars Are Popping Up in Alabama
Yellow jackets in Alabama may be in the midst of a colossal craze; they're making humongous "super nests" that can house 15,000 worker wasps, according to an entomologist there.
57min
Redefining the limits of measurement accuracy
Scientists have introduced a method based on a non-classical state adapted to two measurement parameters at once. This will enable precision measurements of molecules which could reveal interactions between conventional and dark matter.
57min
High brightness mid-infrared laser expands horizon of spectroscopic analytical technique
Researchers have used an extremely bright mid-infrared laser to perform an analytical technique known as spectroscopic ellipsometry. The new approach captures high-resolution spectral information in less than a second and could offer new insights into quickly changing properties of a variety of samples from plastics to biological materials.
57min
Carbohydrate in the heart seems to help regulate blood pressure
New research suggests that a particular type of carbohydrate plays an important role in regulating the blood pressure in the human body. This has been shown by researchers in a new study using rats. The researchers believe that the finding may have a vast potential for improved medications for high blood pressure.
57min
Novel computer model supports cancer therapy
Researchers have developed a computer model that simulates the metabolism of cancer cells. They used the program to investigate how combinations of drugs could be used more effectively to stop tumor growth.
57min
Remote but remarkable: Illuminating the smallest inhabitants of the largest ocean desert
The South Pacific Gyre is an ocean desert. However, due to its vast size the microbial inhabitants of the South Pacific Gyre contribute significantly to global biogeochemical cycles. In an unparalleled investigation, scientists have now made a comprehensive inventory of the microbial community of the South Pacific Gyre. This insight was achieved through the development of a novel tool that enables
57min
New study challenges claim that exogenous RNA is essential for sperm function
Scientists are challenging the claims of two high profile papers from 2018 which reported that in the mouse, RNA has to be added to sperm for them to be fully fertile. The new findings undermine a proposed mechanism of epigenetic inheritance in which offspring inherit traits acquired by their parents.
57min
Mechanical vibration generated by electron spins
Micro mechanical elements are indispensable components of modern electrical devices but the actuation of them requires electrical current. It becomes harder to wire the element as further downscaling of device is pursued. As a way out of this issue, researchers demonstrated a new way to deliver a force to drive micro mechanics by spin current.
57min
Generation and sampling of quantum states of light in a silicon chip
Scientists have found a promising new way to build the next generation of quantum simulators combining light and silicon micro-chips.
57min
California forest die-off caused by depletion of deep-soil water
The inability of long-rooted trees to reach their subsurface water supply in the Sierra Nevada mountain range led to widespread forest die-offs following the drought of 2012-2015. A new study provides a better understanding of the climatic and biological mechanisms in play.
57min
The world needs a global agenda for sand
Sand is a key ingredient in the recipe of modern life, and yet it is being extracted faster than it can be replaced.
57min
Could marijuana be an effective pain alternative to prescription medications?
A new study has shown how cannabis could be an effective treatment option for both pain relief and insomnia, for those looking to avoid prescription and over the counter pain and sleep medications — including opioids.
57min
Researchers Generate Model of Human Embryo from Human Stem Cells
The research may necessitate the formation of new ethical guidelines.
58min
Astronomers help wage war on cancer
Techniques developed by astronomers could help in the fight against breast and skin cancer. Charlie Jeynes at the University of Exeter will present his and Prof Tim Harries team's work today at the RAS National Astronomy Meeting (NAM 2019) at the University of Lancaster.
1h
The world needs a global agenda for sand
Sand is a key ingredient in the recipe of modern life, and yet it is being extracted faster than it can be replaced.
1h
New chemical tools to modify and study biomolecules
Chemists have developed new tools to modify sulfur-containing biomolecules, from simple amino acids to large protein complexes such as nucleosomes. These modifications then provide attachment points for two new functional groups, enabling studies of biochemical interactions on the single-molecule level.
1h
New study showing drug prolongs life for patients with ovarian cancer
Women with ovarian cancer who have undergone four or more rounds of chemotherapy typically haven't had much hope that another treatment option will lengthen their lives in a meaningful way. However, a new research study shows tremendous promise for a drug called niraparib to extend life when all options have been exhausted.
1h
Hematologist and Oncologist Eugene Frenkel Dies
Frenkel investigated drug resistance in cancers and how vitamin B12 deficiency damages neurons.
1h
Saturn's Icy Moon Enceladus Is Likely the 'Perfect Age' to Harbor Life
It's probably around 1 billion years old.
1h
The best 4th of July tech deals weve seen so far
July 4th is upon us. Its a celebration of US independence, and if youre like me, youll be spending it with family, eating lots of grilled food and staying up to watch the fireworks …
1h
Researchers cast neural nets to simulate molecular motion
New work from Los Alamos National Laboratory, the University of North Carolina at Chapel Hill, and the University of Florida is showing that artificial neural nets can be trained to encode quantum mechanical laws to describe the motions of molecules, supercharging simulations potentially across a broad range of fields.
1h
Tiny supersonic jet injector accelerates nanoscale additive manufacturing
By energizing precursor molecules using a tiny, high-energy supersonic jet of inert gas, researchers have dramatically accelerated the fabrication of nanometer scale structures. The rapid additive manufacturing technique also allows them to produce structures with high aspect ratios. Now, a theory developed to describe the technique could lead to new applications for additive nanomanufacturing and
1h
Why do mosquitoes choose us? Lindy McBride is on the case
Carolyn "Lindy" McBride is studying a question that haunts every summer gathering: How and why are mosquitoes attracted to humans?
1h
Why do mosquitoes choose us? Lindy McBride is on the case
Carolyn "Lindy" McBride is studying a question that haunts every summer gathering: How and why are mosquitoes attracted to humans?
1h
The Singularity Has Become a Marketing Gimmick
submitted by /u/Chispy [link] [comments]
1h
Scientists discover processes to lower methane emissions from animals
Scientists are part of an international research collaboration which has made an important discovery in the quest to lower global agricultural methane emissions.
1h
Holy crocodiles
Biologists have researched the cultural status of the reptiles in East Timor.
1h
Maximum weight children should carry in school backpacks
Scientists have established that school children who use backpacks should avoid loads of more than 10% of their body weight — and those who use trolleys, 20% of their body weight.
1h
Tiny granules can help bring clean and abundant fusion power to Earth
Beryllium, a hard, silvery metal long used in X-ray machines and spacecraft, is finding a new role in the quest to bring the power that drives the sun and stars to Earth. Beryllium is one of the two main materials used for the wall in ITER, a multinational fusion facility under construction in France to demonstrate the practicality of fusion power. Now, physicists from the U.S. Department of Energ
1h
NASA Selects 12 New Lunar Experiments in Advance of Human Return
Private spaceflight companies will carry commercial payloads to the Moon in advance of NASA's crewed landing slated for 2024. (Credit: NASA) NASA wants to return humans to the Moon by 2024 under a program called Artemis. And this time, they want the stay to be of a more permanent nature. In addition to landing humans on the lunar surface, NASA wants to put a Gateway space station in orbit around t
1h
Using artificial intelligence to better predict severe weather
When forecasting weather, meteorologists use a number of models and data sources to track shapes and movements of clouds that could indicate severe storms. However, with increasingly expanding weather data sets and looming deadlines, it is nearly impossible for them to monitor all storm formations—especially smaller-scale ones—in real time.
1h
Even today, we want our heroes to know right from wrong
In a world of sympathetic villains and flawed heroes, people still like fictional characters more when they have a strong sense of morality, a new study finds.
1h
Is wildfire management 'for the birds?'
Spotted owl populations are in decline all along the West Coast, and as climate change increases the risk of large and destructive wildfires in the region, these iconic animals face the real threat of losing even more of their forest habitat.
1h
Can mathematics help us understand the complexity of our microbiome?
How do the communities of microbes living in our gastrointestinal systems affect our health? Carnegie's Will Ludington was part of a team that helped answer this question.
1h
Researchers design superhydrophobic 'nanoflower' for biomedical applications
Plant leaves have a natural superpower—they're designed with water repelling characteristics. Called a superhydrophobic surface, this trait allows leaves to cleanse themselves from dust particles. Inspired by such natural designs, a team of researchers at Texas A&M University has developed an innovative way to control the hydrophobicity of a surface to benefit to the biomedical field.
1h
Is wildfire management 'for the birds?'
Spotted owl populations are in decline all along the West Coast, and as climate change increases the risk of large and destructive wildfires in the region, these iconic animals face the real threat of losing even more of their forest habitat.
1h
Brain network evaluates robot likeability
Researchers have identified a network of brain regions that work together to determine if a robot is a worthy social partner, according to a new study.
1h
Can mathematics help us understand the complexity of our microbiome?
How do the communities of microbes living in our gastrointestinal systems affect our health? Carnegie's Will Ludington was part of a team that helped answer this question.
1h
Can we feed 11 billion people while preventing the spread of infectious disease?
Within the next 80 years, the world's population is expected to top 11 billion, creating a rise in global food demand—and presenting an unavoidable challenge to food production and distribution.
1h
Chileans and Argentines gape at total solar eclipse
Tens of thousands of tourists and locals gaped skyward Tuesday as a rare total eclipse of the sun began to darken the heavens over northern Chile.
1h
Data scientist drops Facebook defamation suit
Aleksandr Kogan, the data scientist at the center of Facebook's Cambridge Analytica privacy scandal, said he is dropping a defamation lawsuit against the social network rather than engage in an expensive, drawn-out legal battle.
1h
How 3-D Printing Could Help Shape Surgery
Technology is enabling increasingly lifelike models of organs to help doctors practice operations.
1h
The Human Microbiome: Beyond the Gut
To examine the human microbiome beyond the gut, The Scientist is bringing together experts from the field to share their research, and answer questions from webinar attendees.
1h
Tweeting while watching TV diminishes enjoyment
The most significant impact of two-screen experience was on viewers' ability to 'transport' into the narrative and become immersed in the televised story.
1h
Creating 'movies' of thin film growth
Researchers have demonstrated a new experimental capability for watching thin film growth in real-time. The researchers were able to produce a 'movie' of thin film growth that depicts the process more accurately than traditional techniques can.
1h
New chemical tools to modify and study biomolecules
Chemists have developed new tools to modify sulfur-containing biomolecules, from simple amino acids to large protein complexes such as nucleosomes. These modifications then provide attachment points for two new functional groups, enabling studies of biochemical interactions on the single-molecule level.
1h
Why are we able to see moving objects against moving backgrounds?
If you want your friend to see you in a crowd, you wave your arms to stand out. As University of Rochester researchers found, one reason why this works is that the brain suppresses the background, allowing the person to focus on the moving object in front of them. As we age, our brains become less adept at suppressing background and reacting to foreground movement. But people can train their brain
1h
Top global public health scientists launch new challenge to anti-vaxxers
Search engines and social media organizations must do more to prevent the spread of inaccurate information on childhood vaccination, and governments must better support mandatory immunization programs, says an international group of leading public health scientists.
1h
Supervised fun, exercise both provide psychosocial benefit to children with obesity
A program with clear rules, routines and activities, attentive adults and a chance to interact with peers appears to work as well at improving the quality of life, mood and self-worth of a child who is overweight or obese as a regular exercise program, researchers report.
1h
Response to gene-targeted drugs depends on cancer type
Cancers with the same genetic weaknesses respond differently to targeted drugs depending on the tumour type of the patient, new research reveals. The study is set to prompt changes in thinking around precision medicine — because it shows that the genetics of a patient's cancer may not always be enough to tell whether it will respond to a treatment.
1h
3D holograms bringing astronomy to life
Scientists unravelling the mysteries of star cluster formation have taken inspiration from a 19th century magic trick, to help explain their work to the public. Researchers have developed 3D holograms that allow people to watch massive stars forming before their eyes.
1h
This AI Gives Other AIs Names Like "Ass Federation" And "Hot Pie" Because Robots Can Be Weird Too
Ship Shape Scottish author Iain M. Banks populated his sci-fi Culture book series with humanoid robots, alien races, and artificially intelligent spaceships that chose their own names. So: Research scientist Janelle Shane thought it would be fun to use those ship names to train a real neural network to — what else? — conjure up new names for self-aware spaceships. The results? Hilarious. Puzzling
1h
New epidemic forecast model could save precious resources
When governments and institutions deploy epidemic forecast models when facing an outbreak, they sometimes fail to factor in human behavior and over-allocate precious resources as a result. Thanks to new research authored by a Texas A&M University engineering professor, that may no longer be the case.
1h
Tiny supersonic jet injector accelerates nanoscale additive manufacturing
By energizing precursor molecules using a tiny, high-energy supersonic jet of inert gas, researchers have dramatically accelerated the fabrication of nanometer scale structures. The rapid additive manufacturing technique also allows them to produce structures with high aspect ratios. Now, a theory developed to describe the technique could lead to new applications for additive nanomanufacturing and
1h
Why do mosquitoes choose us? Lindy McBride is on the case
Most of the 3,000+ mosquito species are opportunistic, but Princeton's Lindy McBride is most interested in the mosquitoes that scientists call 'disease vectors' — carriers of diseases that plague humans — some of which have evolved to bite humans almost exclusively. She's trying to understand how the brain and genome of these mosquitoes have evolved to make them specialize in humans — including
1h
Researchers design superhydrophobic 'nanoflower' for biomedical applications
Plant leaves have a natural superpower — they're designed with water repelling characteristics. Called a superhydrophobic surface, this trait allows leaves to cleanse themselves from dust particles. Inspired by such natural designs, a team of researchers at Texas A&M University has developed an innovative way to control the hydrophobicity of a surface to benefit to the biomedical field.
1h
Can we feed 11 billion people while preventing the spread of infectious disease?
A new article published in Nature Sustainability describes how the increase in population and the need to feed everyone will give rise to human infectious disease, a situation the authors of the paper consider 'two of the most formidable ecological and public health challenges of the 21st century.'
1h
Sister, neighbor, friend: Thinking about multiple roles boosts kids' performance
A typical child plays many roles, such as friend, neighbor, son or daughter. Simply reminding children of that fact can lead to better problem-solving and more flexible thinking, finds new research from Duke University. Better problem-solving was just one positive finding of the study, Gaither said. After considering their own various identities, children also showed more flexible thinking about r
1h
Study suggests genetic testing for young people diagnosed with type 1 diabetes
A Joslin Diabetes Center study among people treated for type 1 diabetes for many years has discovered that a minority may have monogenic diabetes, a non-autoimmune inherited condition that in some cases does not require insulin treatment. 'Our finding has clinical implications,' says George L. King, MD, 'We are recommending that everyone under 18 who is diagnosed with type 1 diabetes be screened f
1h
Researchers cast neural nets to simulate molecular motion
New work from Los Alamos National Laboratory, the University of North Carolina at Chapel Hill, and the University of Florida is showing that artificial neural nets can be trained to encode quantum mechanical laws to describe the motions of molecules, supercharging simulations potentially across a broad range of fields.
1h
Cholesterol that is too low may boost risk for hemorrhagic stroke
Current guidelines recommend lowering cholesterol for heart disease risk reduction. New findings indicate that if cholesterol dips too low, it may boost the risk of hemorrhagic stroke, according to researchers.
1h
Watch the 2019 Solar Eclipse as Seen in Chile and Argentina
The eclipse barreled across South America on Tuesday.
1h
What You Need to Know About the Zika Virus and Travel
The virus has been out of the headlines, but that doesn't mean it is gone. The World Health Organization just updated its guidelines for travelers to the Zika zone.
1h
The Zika Virus Is Still a Threat. Here's What Experts Know.
The mosquito-transmitted virus, which can cause severe birth defects, faded after 2016, but it's still circulating and has now spread to other countries.
1h
Elizabeth Warren Calls on Former F.D.A. Chief to Quit Pfizer Board
The Democratic presidential candidate rebuked Dr. Scott Gottlieb, saying his decision to align with a major drug company "smacks of corruption."
1h
Climate Change Denialists Dubbed Auto Makers the 'Opposition' in Fight Over Trump's Emissions Rollback
Newly released government emails show how climate denier groups quickly dominated the internal discussion over the historic rollback of the Obama-era climate rules.
1h
An Arctic Fox's Epic Journey: Norway to Canada in 76 Days
The animal amazed researchers by trekking more than 2,175 miles across continents, including a stunning run across sea ice.
1h
Scientists 'Thunderstruck' As Arctic Fox Makes Stunning 2,100-Mile Journey in Just 76 Days
Scientists who tracked the young female were astonished by how fast the little fox traveled from Norway to Canada.
2h
Tiny granules can help bring clean and abundant fusion power to Earth
Physicists from PPPL and General Atomics have concluded that injecting tiny beryllium pellets into ITER could help stabilize the plasma that fuels fusion reactions.
2h
Combat veterans more likely to experience mental health issues in later life
Military veterans exposed to combat were more likely to exhibit signs of depression and anxiety in later life than veterans who had not seen combat, a new study from Oregon State University shows.
2h
Unraveling the brain's reward circuits
Food, alcohol, and certain drugs all act to reduce the activity of hunger neurons and to release reward signals in the brain, but alcohol and drugs rely on a different pathway than does food, according to a new study led by University of Pennsylvania biologists. The findings could point researchers to new strategies to design weight-loss or anti-addiction drugs.
2h
Is wildfire management 'for the birds?'
Spotted owl populations are in decline all along the West Coast, and as climate change increases the risk of large and destructive wildfires in the region, these iconic animals face the real threat of losing even more of their forest habitat. Wildfire management — through prescribed burning and restoration thinning — could help save the species, argues a new paper.
2h
Foundational study explores role of diet in diabetes complications
A pressing question in diabetes research is how elevated blood levels of sugar, cholesterol, and fat may contribute to blood vessel damage in relation to the diet. A new study by investigators from Brigham and Women's Hospital set out to determine which components of the Western diet — one rich in sugar, cholesterol and fat — may worsen diabetes complications.
2h
Can mathematics help us understand the complexity of our microbiome?
In humans, the gut microbiome is an ecosystem of hundreds to thousands of microbial species living within the gastrointestinal tract, influencing health and even longevity. As interest in studying the microbiome continues to increase, understanding this complexity will give us predictive power to engineer it. A research team led by Carnegie's Will Ludington built a rigorous mathematical framework
2h
Methane vanishing on Mars
Wind-driven erosion of minerals on Mars may be the reason why methane disappears so rapidly on the red planet. Saltation causes electrical charges, that can oxidize minerals and ionize gases like methane, making the ionized methane bond to the minerals. That is the explanation proposed by an interdisciplinary research group, based on laboratory experiments in a Mars-like environment.
2h
Brain network evaluates robot likeability
Researchers have identified a network of brain regions that work together to determine if a robot is a worthy social partner, according to a new study.
2h
Lost Palace of a Once-Mighty Empire Unearthed in Iraq
The site was part of the Mittani Empire, a kingdom of the Ancient Near East.
2h
What Is Trypophobia?
Thousands of people claim to experience trypophobia, or a fear of clustered holes, but science hasn't settled on the origin of their fear.
2h
Fast radio burst pinpointed to distant galaxy
In a rare feat, astronomers have pinpointed the place of origin of a fast radio burst, with a surprising outcome.
2h
The Human Microbiome: Beyond the Gut
To examine the human microbiome beyond the gut, The Scientist is bringing together experts from the field to share their research, and answer questions from webinar attendees.
2h
Mentoring becomes more widely accepted as a part of teacher training methodology
As the authors posit, contemporary pedagogical ideas and approaches cannot fully satisfy the existing graduate requirements because of rapid informatization, intellectualization and technological progress.
2h
Using artificial intelligence to better predict severe weather
When forecasting weather, meteorologists use a number of models and data sources to track shapes and movements of clouds that could indicate severe storms. However, with increasingly expanding weather data sets and looming deadlines, it is nearly impossible for them to monitor all storm formations — especially smaller-scale ones — in real time.
2h
Pesticide exposure linked to teen depression in agricultural communities
Adolescent depression increases with exposure to pesticides, a study in the Ecuadorian Andes shows.
2h
The Human Microbiome: Beyond the Guy
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2h
Science is here to validate your PMS cravings
What makes chips and chocolate so appealing at certain times of the month? (Ken Tannenbaum/Shutterstock.com/) Premenstrual food cravings are the punchline of endless jokes. Like most good jokes, they're funny because they're true. Certain parts of a woman's menstrual cycle do seem to go hand in hand with the desire for chocolate ice cream and potato chips. I hear about this every day from my OBGY
2h
Even today, we want our heroes to know right from wrong
In a world of sympathetic villains and flawed heroes, people still like fictional characters more when they have a strong sense of morality, a new study finds.Researchers found that people best liked the heroes they rated as most moral, and least liked villains they rated as most immoral.
2h
Russian engineers ready to 'light up' a lamp revolution
Researchers from the Moscow Institute of Physics and Technology and Lebedev Physical Institute of the Russian Academy of Sciences have designed and tested a prototype cathodoluminescent lamp for general lighting. The new lamp, which relies on the phenomenon of field emission, is more reliable, durable, and luminous than its analogues available worldwide.
2h
At 21, Ann Montgomery Became a Lead Engineer at NASA, Managing the Cameras and Other Crucial Gear Used on the Moon
Montgomery worked closely with the Apollo astronauts to train them to use handheld tools and equipment on the moon
2h
Researchers say they're closer to finding cure for HIV after using CRISPR technology to eliminate disease in live mice for the first time
submitted by /u/izumi3682 [link] [comments]
2h
The Planetary Society's crowdfunded LightSail 2 officially orbiting on its own after being delivered to space via SpaceX's Falcon Heavy last week.
submitted by /u/davidwholt [link] [comments]
2h
Climate change made record-breaking heatwaves at least five times more likely. Temperature records were also broken in France, Switzerland, Australia, Germany and Spain last week — with the UK's high of 34C on Saturday
submitted by /u/Wagamaga [link] [comments]
2h
PBS Space Time – Thorium and the Future of Nuclear Energy [Jul 1, 2019]
submitted by /u/espresso__patronum [link] [comments]
2h
How a genetically-engineered phage therapy defeated a drug-resistant infection, raising hopes for chronically ill patients
submitted by /u/V2O5 [link] [comments]
2h
Explorers to voyage to Japan in primitive boat in hopes of unlocking an ancient mystery
40-hour, 200-kilometer canoe trip recreates the sea journeys that may have peopled Japan's Okinawan islands
2h
Att bromsa åldrandet inte längre science fiction
Åldrandet börjar i cellernas inre. Med en allt högre levnadsstandard lever vi längre. Men åldrandet har ett pris i form av sjukdomar som cancer, diabetes typ II, Parkinson och Alzheimer. Men tänk om vi kan senarelägga eller förhindra sjukdomarna genom att göra något åt åldrandet i sig ? Att åldras utan att bli skröplig. Hoppet växer ju mer vi lär oss om vad som händer i cellens inre. Det pågår et
3h
Here's How You Can Watch Today's Total Solar Eclipse
Heads up: For approximately four minutes this afternoon, the Moon will block out the Sun over parts of South America — but you don't need to be in Chile or Argentina to see the stunning spectacle. California's Exploratorium has teamed up with NASA to broadcast a livestream of the eclipse via the video linked below. The coverage will begin at 3 p.m. ET, with the eclipse expected to take place betw
3h
Climate change made Europe's mega-heatwave five times more likely
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02071-z Scientists raced to study whether the scorching temperatures last week were linked to global warming.
3h
Bonobos Get Their Iodine From Swampy Plants — Ancient Humans Might Have As Well
(Credit: Sergey Uryadnikov/Shutterstock) Within the rainforests of Salonga National Park, in the heart of the Democratic Republic of the Congo, bonobos wade through swamps. The slender, three-and-a-half-foot tall apes are searching for rushes and white water lilies. They pluck the herbs from the water and then discard the flowers and leaves. The bonobos are after the soft pith at the base of the l
3h
New stillbirth risk figures help women's decisions on timing delivery
The researchers from Queen Mary University of London say that women who are 41 weeks pregnant should not be alarmed, as the increased risk is low — equivalent to one additional stillbirth for every 1,449 pregnancies, compared to delivering at 40 weeks.
3h
A NEAT discovery about memory
UAB researchers say over expression of NEAT1, an noncoding RNA, appears to diminish the ability of older brains to form memories. Inhibiting NEAT1 via CRISPR technology could be a means to improve memory in older humans.
3h
Higher risk of stillbirth in longer pregnancies, study finds
The longer a pregnancy continues past 37 weeks gestation, the higher the risk of a stillbirth, according to a new meta-analysis published this week in PLOS Medicine by Shakila Thangaratinam of Queen Mary University of London, UK, and colleagues.
3h
Solitude breeds aggression in spiders (rather than vice versa)
Spiders start out social but later turn aggressive after dispersing and becoming solitary, according to a study publishing July 2 in the open-access journal PLOS Biology by Raphael Jeanson of the National Centre for Scientific Research (CNRS) in France, and colleagues.
3h
My Encounter with the Late Mitchell Feigenbaum, Chaos Pioneer and Critic
Renowned discoverer of order underlying chaos was surprising skeptical of claims that computers were creating a revolutionary new science. — Read more on ScientificAmerican.com
3h
University Releases Reports from Investigation of Prominent Geneticist
A panel finds David Latchman's "recklessness in the conduct" of the lab and his involvement as an author on problematic papers facilitated the misconduct.
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How to find the best Spotify playlists when you don't want to make your own
If you're stuck for inspiration, Spotify can help. (Mildly Useful via Unsplash/) With more than 50 million tracks available at the push of a button, Spotify gives you access to more music than you could possibly listen to in a lifetime—a rather daunting catalog when all you want to do is pick out a playlist for a summer drive or evening chill out. But if you don't want to build your own playlists
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Social isolation makes spiders aggressive
Research shows they're a lot happier staying in groups. Natalie Parletta reports.
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Stillbirth a greater risk past 37 weeks
Findings should inform decisions but not cause alarm, researchers say. Nick Carne reports.
4h
Solitude breeds aggression in spiders (rather than vice versa)
Spiders start out social but later turn aggressive after dispersing and becoming solitary, according to a study publishing July 2 in the open-access journal PLOS Biology by Raphael Jeanson of the National Centre for Scientific Research (CNRS) in France, and colleagues.
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Caroline Criado Perez Explains the 'Gender Data Gap'
In this WIRED Q&A, author Caroline Criado Perez explains how elements of the modern world were designed more for men than women.
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Solitude breeds aggression in spiders (rather than vice versa)
Spiders start out social but later turn aggressive after dispersing and becoming solitary, according to a study publishing July 2 in the open-access journal PLOS Biology by Raphael Jeanson of the National Centre for Scientific Research (CNRS) in France, and colleagues.
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My Encounter with the Late Mitchell Feigenbaum, Chaos Pioneer and Critic
Renowned discoverer of order underlying chaos was surprising skeptical of claims that computers were creating a revolutionary new science. — Read more on ScientificAmerican.com
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Why are intelligent people more likely to abuse drugs?
Numerous studies have confirmed the link between intelligence and substance abuse. However, the mechanism for this correlation has been difficult to pin down. Why would more intelligent people, who should ostensibly know better, practice such a risky habit? None No mathematician has ever published more papers than Paul Erdős. The 20th-century mathematician was brilliant, eccentric, and prolific,
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The U.S. Women's Soccer Team Must Win
When the U.S. women's national soccer team takes the field against England in today's Women's World Cup semifinal match, they will be playing for far more than another piece of hardware for their trophy shelf. Last week, the team's co-captain Megan Rapinoe said in a press interview that should they win the Cup, she would not go "to the fucking White House." President Donald Trump responded via Tw
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Photos: Hong Kong Protesters Break Into Legislative Council Building
On Monday, the anniversary of Britain's handover of Hong Kong to China, huge numbers of pro-democracy protesters marched peacefully through the city. Late in the day, a large group of demonstrators from the mostly leaderless movement broke off and faced off against riot police at Hong Kong's Legislative Council building. Eventually, they smashed their way into the building and swarmed inside, dam
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What Is Relativity?
Albert Einstein was famous for many things, but his greatest brainchild is the theory of relativity. It forever changed our understanding of space and time.
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Austrian parliament approves total glyphosate ban
Austrian lawmakers on Tuesday approved a total ban on glyphosate, putting the country on track to becoming the first EU member to forbid all use of the controversial herbicide.
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Irrigated farming in Wisconsin's central sands cools the region's climate
New research finds that irrigated farms within Wisconsin's vegetable-growing Central Sands region significantly cool the local climate compared to nearby rain-fed farms or forests.
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Barbara now a major hurricane on NASA satellite imagery
NASA's Terra and Aqua satellites passed over the Eastern Pacific Ocean after Tropical Storm Barbara strengthened into the first hurricane of the season. Barbara intensified rapidly into a major hurricane.
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Austrian parliament approves total glyphosate ban
Austrian lawmakers on Tuesday approved a total ban on glyphosate, putting the country on track to becoming the first EU member to forbid all use of the controversial herbicide.
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Fast radio burst pinpointed to distant galaxy
Fast radio bursts (FRBs) are among the most enigmatic and powerful events in the cosmos. Around 80 of these events—intensely bright millisecond-long bursts of radio waves coming from beyond our galaxy—have been witnessed so far, but their causes remain unknown.
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Automakers report dip in US sales through midyear
US automakers reported a dip in sales for the first half of 2019 on Tuesday as higher vehicle costs offset generally solid economic conditions.
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New study challenges claim that exogenous RNA is essential for sperm function
Scientists from the University of Bath are challenging the claims of two high profile papers from 2018 which reported that in the mouse, RNA has to be added to sperm for them to be fully fertile. The Bath findings undermine a proposed mechanism of epigenetic inheritance in which offspring inherit traits acquired by their parents.
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The world needs a global agenda for sand
What links the building you live in, the glass you drink from and the computer you work on? The answer is smaller than you think and is something we are rapidly running out of: sand.
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New study challenges claim that exogenous RNA is essential for sperm function
Scientists from the University of Bath are challenging the claims of two high profile papers from 2018 which reported that in the mouse, RNA has to be added to sperm for them to be fully fertile. The Bath findings undermine a proposed mechanism of epigenetic inheritance in which offspring inherit traits acquired by their parents.
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Gold nanoparticles promise safe cancer drugs, better vaccines
A new study suggests that targeting B cells with gold nanoparticles could be a safe way to improve vaccines and treatments for cancer and other diseases.
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Facebook acts on 'sensational' health cures after report
Facebook and YouTube said Tuesday they were moving to reduce the spread of misleading health care claims after a media report showed the proliferation of bogus cancer cures on social media.
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Climate change made French heatwave 'more likely' in hottest June ever
The record-breaking heatwave that gripped France last week was made at least five times more likely by climate change, scientists said Tuesday as other data showed that last month was the hottest June worldwide in history.
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Heavy rainfall ends prolonged drought in Southern Plains
The rooms at Crappie King Cabins near northwestern Oklahoma's Canton Lake were mostly empty when much of the state and the rest of the Southern Plains were in the grip of a prolonged, withering drought that sent lake levels plummeting.
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French protesters block Amazon sites over climate, jobs
Environmental activists chained themselves to gates and turnstiles Tuesday as they occupied an Amazon building near Paris, accusing the online company of destroying jobs and hurting the planet.
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Arctic fox walks more than 2,700 miles from Norway to Canada
Norwegian researchers say an arctic fox walked from northern Norway to Canada's far north, a distance of 4,415 kilometers (2,737 miles), in four months.
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VR – Humanity's Next Addiction
submitted by /u/BlackAera [link] [comments]
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Engineers and Architects Are Already Designing Lunar Habitats
submitted by /u/minterbartolo [link] [comments]
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MIT develops tiny 'walking' motor that helps more complex robots self-assemble | "In future, the idea is that these tiny core machines could actually automatically self-assemble into larger structures capable of carrying out specific tasks"
submitted by /u/yourSAS [link] [comments]
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Himalayan glaciers in India are receding at highly alarming rate. Debris of thickness above two centimetres have reduced the melting rates up to 70 per cent, whereas the debris cover of below two centimetres thickness has accelerated melting up to 10 per cent of the total melting.
submitted by /u/Wagamaga [link] [comments]
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Antarctica melts faster than ever before and the extent of its ice sheet last May was the lowest recorded, informed spokeswoman of the World Meteorological Organization (WMO), Clare Nullis.
submitted by /u/Wagamaga [link] [comments]
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This Radical New DNA Microscope Reimagines the Cellular World
submitted by /u/dwaxe [link] [comments]
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Ahead of 2020, Beware the Deepfake
"We are crossing over into an era where we have to be skeptical of what we see on video," says John Villasenor, a senior fellow at the Brookings Institution. Villasenor is talking about deepfakes —videos that are digitally manipulated in imperceptible ways, often using a machine-learning technique that superimposes existing images or audio onto source material. The technology's verisimilitude is
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Europe's latest heat wave has been linked to climate change
Global warming made the June heat wave at least five times more likely to happen.
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Arctic fox walks more than 2,700 miles from Norway to Canada
Norwegian researchers say an arctic fox walked from northern Norway to Canada's far north, a distance of 4,415 kilometers (2,737 miles), in four months.
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World's Smallest MRI Machine Means We Can Now Scan Individual Atoms
MRI for Ants Atoms Magnetic resonance imaging (MRI) machines are great for creating detailed images of a person's internal organs and tissues. Using magnets and radio waves, the machines temporarily change how the billions of protons in the person's body spin. Then they measure and image energy released by these protons once they return to their normal state. Now, researchers have created a versi
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Barbara now a major hurricane on NASA satellite imagery
NASA's Terra and Aqua satellites passed over the Eastern Pacific Ocean after Tropical Storm Barbara strengthened into the first hurricane of the season. Barbara intensified rapidly into a major hurricane.
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New method makes realistic water wave animations more efficient
Producing high-quality and realistic water wave animations that interact with complex objects is often computationally expensive with designers frequently opting for methods that are fast to compute but of lower quality. Researchers at the Institute of Science and Technology Austria (IST Austria) have developed a technique to produce more realistic water wave animations at a similar computational
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Irrigated farming in Wisconsin's central sands cools the region's climate
Irrigation dropped maximum temperatures by one to three degrees Fahrenheit on average while increasing minimum temperatures up to four degrees compared to unirrigated farms or forests, new research shows In all, irrigated farms experienced a three- to seven-degree smaller range in daily temperatures compared to other land uses. These effects persisted throughout the year.
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DNA from tooth in Florida man's foot solves 25-year-old shark bite mystery
When Jeff Weakley tweezed open a blister-like bulge on his foot, he was not expecting to find a piece of tooth from a shark that bit him while he was surfing off Flagler Beach in 1994.
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Researcher reports the way sickle cells form may be key to stopping them
University of Houston associate professor of chemistry, Vassiliy Lubchenko, is reporting a new finding in Nature Communications on how sickle cells are formed. Lubchenko reports that droplets of liquid, enriched in hemoglobin, form clusters inside some red blood cells when two hemoglobin molecules form a bond—but only briefly, for one thousandth of a second or so.
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DNA from tooth in Florida man's foot solves 25-year-old shark bite mystery
When Jeff Weakley tweezed open a blister-like bulge on his foot, he was not expecting to find a piece of tooth from a shark that bit him while he was surfing off Flagler Beach in 1994.
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Researcher reports the way sickle cells form may be key to stopping them
University of Houston associate professor of chemistry, Vassiliy Lubchenko, is reporting a new finding in Nature Communications on how sickle cells are formed. Lubchenko reports that droplets of liquid, enriched in hemoglobin, form clusters inside some red blood cells when two hemoglobin molecules form a bond—but only briefly, for one thousandth of a second or so.
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Skills are the new coin of the realm
Forget bitcoin—skills are the global currency for 21st century economies. Lori Foster, professor of Psychology at North Carolina State University and the University of Cape Town, says, "Without proper investment in skills, individuals languish on the margins of societies, technology does not convert into economic prosperity, and it's difficult if not impossible for countries to compete in an incre
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Why some cities turn off the water pipes at night
For more than a billion people around the world, running water comes from "intermittent systems" that turn on and off at various times of the week. A new paper by University of Toronto Engineering professor David Taylor proposes a simple, yet powerful model to explain why and how these systems come to be—and how they fit into the global challenge of meeting international targets for human developm
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Proteins trapped in glass could yield new medicinal advances
Researchers at Chalmers University of Technology, Sweden, have developed a unique method for studying proteins which could open new doors for medicinal research. Through capturing proteins in a nano-capsule made of glass, the researchers have been able to create a unique model of proteins in natural environments. The results are published in the scientific journal, Small.
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For Smart Animals, Octopuses Are Very Weird
A small shark spots its prey—a meaty, seemingly defenseless octopus. The shark ambushes, and then, in one of the most astonishing sequences in the series Blue Planet II , the octopus escapes. First, it shoves one of its arms into the predator's vulnerable gills. Once released, it moves to protect itself—it grabs discarded seashells and swiftly arranges them into a defensive dome. Thanks to acts l
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Scientists: Sorry, 'Oumuamua Still Isn't an Alien Spaceship
A comprehensive analysis from scientists at the University of Maryland and other institutions has ruined our fun once and for all. 'Oumuamua isn't an alien spaceship. The post Scientists: Sorry, 'Oumuamua Still Isn't an Alien Spaceship appeared first on ExtremeTech .
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Bionic catalysts to produce clean energy
Mixing microbes with carbon nanomaterials could help the transition to renewable energy. KAUST research shows microbes and nanomaterials can be used together to form a biohybrid material that performs well as an electrocatalyst. The material could be used in the solar-powered production of carbon-free fuels and several other green-energy applications.
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Atmosphere of mid-size planet revealed by Hubble and Spitzer
Two NASA space telescopes have teamed up to identify, for the first time, the detailed chemical "fingerprint" of a planet between the sizes of Earth and Neptune. No planets like this can be found in our own solar system, but they are common around other stars.
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High brightness mid-infrared laser expands horizon of spectroscopic analytical technique
Researchers have used an extremely bright mid-infrared laser to perform an analytical technique known as spectroscopic ellipsometry. The new approach captures high-resolution spectral information in less than a second and could offer new insights into quickly changing properties of a variety of samples from plastics to biological materials.
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The new racial disparity in special education
Racial disparity in special education is growing, and it's more complex than previously thought. New research from Michigan State University examined how often black and Hispanic students are identified as needing special education compared to white students, leading to new findings on disproportionality and racial gaps.
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Creating 'movies' of thin film growth
From paint on a wall to tinted car windows, thin films make up a wide variety of materials found in ordinary life. But thin films are also used to build some of today's most important technologies, such as computer chips and solar cells. Seeking to improve the performance of these technologies, scientists are studying the mechanisms that drive molecules to uniformly stack together in layers—a proc
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Tracking down dark matter
Matter surrounds us day and night in all its forms—trees, houses, furniture, and even the air we breathe. But, according to physicists, the visible matter familiar to us may only account for approximately 20 percent of all material in the universe. According to the current theory, as much as 80 percent may be dark matter. This claim is based on several observations, one of which is that stars and
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New study shows nanoscale pendulum coupling
In 1665, Lord Christiaan Huygens found that two pendulum clocks, hung in the same wooden structure, oscillated spontaneously and perfectly in line but in opposite directions: the clocks oscillated in anti-phase. Since then, synchronization of coupled oscillators in nature has been described at several scales: from heart cells to bacteria, neural networks and even in binary star systems -spontaneou
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Treg-mediated prolonged survival of skin allografts without immunosuppression [Immunology and Inflammation]
Injection of Interleukin-2 (IL-2) complexed with a particular anti–IL-2 monoclonal antibody (mab) JES6-1 has been shown to selectively expand CD4+Foxp3+ T regulatory T cells (Tregs) in vivo. Although the potency of this approach with regard to transplantation has already been proven in an islet transplantation model, skin graft survival could…
5h
Morphine tolerance is attenuated in germfree mice and reversed by probiotics, implicating the role of gut microbiome [Medical Sciences]
Prolonged exposure to opioids results in analgesic tolerance, drug overdose, and death. The mechanism underlying morphine analgesic tolerance still remains unresolved. We show that morphine analgesic tolerance was significantly attenuated in germfree (GF) and in pan-antibiotic−treated mice. Reconstitution of GF mice with naïve fecal microbiota reinstated morphine analgesic tolerance. We…
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Up-regulation of FOXO1 and reduced inflammation by {beta}-hydroxybutyric acid are essential diet restriction benefits against liver inȷury [Medical Sciences]
Liver ischemia and reperfusion injury (IRI) is a major challenge in liver surgery. Diet restriction reduces liver damage by increasing stress resistance; however, the underlying molecular mechanisms remain unclear. We investigated the preventive effect of 12-h fasting on mouse liver IRI. Partial warm hepatic IRI model in wild-type male C57BL/6…
5h
Intracellular mechanisms of fungal space searching in microenvironments [Microbiology]
Filamentous fungi that colonize microenvironments, such as animal or plant tissue or soil, must find optimal paths through their habitat, but the biological basis for negotiating growth in constrained environments is unknown. We used time-lapse live-cell imaging of Neurospora crassa in microfluidic environments to show how constraining geometries determine the…
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Pulcherrimin formation controls growth arrest of the Bacillus subtilis biofilm [Microbiology]
Biofilm formation by Bacillus subtilis is a communal process that culminates in the formation of architecturally complex multicellular communities. Here we reveal that the transition of the biofilm into a nonexpanding phase constitutes a distinct step in the process of biofilm development. Using genetic analysis we show that B. subtilis…
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The purine biosynthesis regulator PurR moonlights as a virulence regulator in Staphylococcus aureus [Microbiology]
The pathogen Staphylococcus aureus colonizes and infects a variety of different sites within the human body. To adapt to these different environments, S. aureus relies on a complex and finely tuned regulatory network. While some of these networks have been well-elucidated, the functions of more than 50% of the transcriptional…
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CarD contributes to diverse gene expression outcomes throughout the genome of Mycobacterium tuberculosis [Microbiology]
The ability to regulate gene expression through transcription initiation underlies the adaptability and survival of all bacteria. Recent work has revealed that the transcription machinery in many bacteria diverges from the paradigm that has been established in Escherichia coli. Mycobacterium tuberculosis (Mtb) encodes the RNA polymerase (RNAP)-binding protein CarD, which…
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Shigella promotes major alteration of gut epithelial physiology and tissue invasion by shutting off host intracellular transport [Microbiology]
Intracellular trafficking pathways in eukaryotic cells are essential to maintain organelle identity and structure, and to regulate cell communication with its environment. Shigella flexneri invades and subverts the human colonic epithelium by the injection of virulence factors through a type 3 secretion system (T3SS). In this work, we report the…
5h
Role of cerebellar GABAergic dysfunctions in the origins of essential tremor [Neuroscience]
Essential tremor (ET) is among the most prevalent movement disorders, but its origins are elusive. The inferior olivary nucleus (ION) has been hypothesized as the prime generator of tremor because of the pacemaker properties of ION neurons, but structural and functional changes in ION are unlikely under ET. Abnormalities have…
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Circuit-specific control of the medial entorhinal inputs to the dentate gyrus by atypical presynaptic NMDARs activated by astrocytes [Neuroscience]
Here, we investigated the properties of presynaptic N-methyl-d-aspartate receptors (pre-NMDARs) at corticohippocampal excitatory connections between perforant path (PP) afferents and dentate granule cells (GCs), a circuit involved in memory encoding and centrally affected in Alzheimer's disease and temporal lobe epilepsy. These receptors were previously reported to increase PP release probability.
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Synaptic crosstalk conferred by a zone of differentially regulated Ca2+ signaling in the dendritic shaft adjoining a potentiated spine [Neuroscience]
Patterns of postsynaptic activity that induce long-term potentiation of fast excitatory transmission at glutamatergic synapses between hippocampal neurons cause enlargement of the dendritic spine and promote growth in spine endoplasmic reticulum (ER) content. Such postsynaptic activity patterns also impact Ca2+ signaling in the adjoining dendritic shaft, in a zone centered…
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Region-specific and activity-dependent regulation of SVZ neurogenesis and recovery after stroke [Neuroscience]
Stroke is the leading cause of adult disability. Neurogenesis after stroke is associated with repair; however, the mechanisms regulating poststroke neurogenesis and its functional effect remain unclear. Here, we investigate multiple mechanistic routes of induced neurogenesis in the poststroke brain, using both a forelimb overuse manipulation that models a clinical…
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Asymmetries between achromatic and chromatic extraction of 3D motion signals [Neuroscience]
Motion in depth (MID) can be cued by high-resolution changes in binocular disparity over time (CD), and low-resolution interocular velocity differences (IOVD). Computational differences between these two mechanisms suggest that they may be implemented in visual pathways with different spatial and temporal resolutions. Here, we used fMRI to examine how…
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Pattern of dopamine signaling during aversive events predicts active avoidance learning [Neuroscience]
Learning to avoid aversive outcomes is an adaptive strategy to limit one's future exposure to stressful events. However, there is considerable variance in active avoidance learning across a population. The mesolimbic dopamine system contributes to behaviors elicited by aversive stimuli, although it is unclear if the heterogeneity in active avoidance…
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{alpha}2-Chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis [Neuroscience]
Adult hippocampal neurogenesis involves the lifelong generation of neurons. The process depends on the homeostasis of the production of neurons and maintenance of the adult neural stem cell (NSC) pool. Here, we report that α2-chimaerin, a Rho GTPase-activating protein, is essential for NSC homeostasis in adult hippocampal neurogenesis. Conditional deletion…
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The network organization of rat intrathalamic macroconnections and a comparison with other forebrain divisions [Neuroscience]
The thalamus is 1 of 4 major divisions of the forebrain and is usually subdivided into epithalamus, dorsal thalamus, and ventral thalamus. The 39 gray matter regions comprising the large dorsal thalamus project topographically to the cerebral cortex, whereas the much smaller epithalamus (2 regions) and ventral thalamus (5 regions)…
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Leptin's hunger-suppressing effects are mediated by the hypothalamic-pituitary-adrenocortical axis in rodents [Neuroscience]
Leptin informs the brain about sufficiency of fuel stores. When insufficient, leptin levels fall, triggering compensatory increases in appetite. Falling leptin is first sensed by hypothalamic neurons, which then initiate adaptive responses. With regard to hunger, it is thought that leptin-sensing neurons work entirely via circuits within the central nervous…
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Reversible silencing of endogenous receptors in intact brain tissue using 2-photon pharmacology [Pharmacology]
The physiological activity of proteins is often studied with loss-of-function genetic approaches, but the corresponding phenotypes develop slowly and can be confounding. Photopharmacology allows direct, fast, and reversible control of endogenous protein activity, with spatiotemporal resolution set by the illumination method. Here, we combine a photoswitchable allosteric modulator (alloswitch) and.
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A comprehensive genomic scan reveals gene dosage balance impacts on quantitative traits in Populus trees [Plant Biology]
Gene dosage variation and the associated changes in gene expression influence a wide variety of traits, ranging from cancer in humans to yield in plants. It is also expected to affect important traits of ecological and agronomic importance in forest trees, but this variation has not been systematically characterized or…
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Low cationicity is important for systemic in vivo efficacy of database-derived peptides against drug-resistant Gram-positive pathogens [Medical Sciences]
As bacterial resistance to traditional antibiotics continues to emerge, new alternatives are urgently needed. Antimicrobial peptides (AMPs) are important candidates. However, how AMPs are designed with in vivo efficacy is poorly understood. Our study was designed to understand structural moieties of cationic peptides that would lead to their successful use…
5h
Correction for Chao et al., Systematic assessment of the sex ratio at birth for all countries and estimation of national imbalances and regional reference levels [Correction]
SOCIAL SCIENCES Correction for "Systematic assessment of the sex ratio at birth for all countries and estimation of national imbalances and regional reference levels," by Fengqing Chao, Patrick Gerland, Alex R. Cook, and Leontine Alkema, which was first published April 15, 2019; 10.1073/pnas.1812593116 (Proc. Natl. Acad. Sci. U.S.A. 116, 9303–9311)….
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Correction for Dvir et al., Deciphering the rules by which 5'-UTR sequences affect protein expression in yeast [Correction]
BIOPHYSICS AND COMPUTATIONAL BIOLOGY Correction for "Deciphering the rules by which 5′-UTR sequences affect protein expression in yeast," by Shlomi Dvir, Lars Velten, Eilon Sharon, Danny Zeevi, Lucas B. Carey, Adina Weinberger, and Eran Segal, which was first published July 5, 2013; 10.1073/pnas.1222534110 (Proc. Natl. Acad. Sci. U.S.A. 110, E2792–E2801)….
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Correction for Davis et al., In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation [Correction]
NEUROSCIENCE, PSYCHOLOGICAL AND COGNITIVE SCIENCES Correction for "In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation," by Margaret T. Davis, Ansel Hillmer, Sophie E. Holmes, Robert H. Pietrzak, Nicole DellaGioia, Nabeel Nabulsi, David Matuskey, Gustavo Angarita-Africano, Richard E. Carson, John H. Krystal, and Irina Esterlis, which…
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Correction for Derrien et al., Degradation of the antiviral component ARGONAUTE1 by the autophagy pathway [Correction]
PLANT BIOLOGY Correction for "Degradation of the antiviral component ARGONAUTE1 by the autophagy pathway," by Benoît Derrien, Nicolas Baumberger, Mikhail Schepetilnikov, Corrado Viotti, Julia De Cillia, Véronique Ziegler-Graff, Erika Isono, Karin Schumacher, and Pascal Genschik, which was first published September 10, 2012; 10.1073/pnas.1209487109 (Proc. Natl. Acad. Sci. U.S.A. 109, 15942–15946)..
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In This Issue [This Week in PNAS]
Controlled twisting of advanced materials into complex structures 3D microstructure in the form of a flower, created by buckling and twisting a 2D precursor. Advances in 3D manufacturing have enabled the production of complex 3D architectures, but existing manufacturing techniques are limited in the types of achievable geometries. Hangbo Zhao,…
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Water is not a dynamic polydisperse branched polymer [Physical Sciences]
In PNAS, Naserifar and Goddard (1) report that their RexPoN water model under ambient conditions comprises a "dynamic polydisperse branched polymer," which they speculate explains the existence of the liquid–liquid critical point (LLCP) in the supercooled region. The observable they rely on to support this is the oxygen–oxygen radial distribution…
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Mathematical models converge on PGC1{alpha} as the key metabolic integrator of SIRT1 and AMPK regulation of the circadian clock [Biological Sciences]
How the mammalian circadian clock interacts with metabolism and its possible implications in metabolic diseases are actively studied. In PNAS, Foteinou et al. (1) propose a mathematical model of the circadian clock that incorporates the metabolic sensor SIRT1 and validate it with cell experiments. Their findings shed light on conflicting…
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Reply to Furlan et al.: The role of SIRT1 in cell autonomous clock function [Biological Sciences]
As the mathematical model developed by Woller et al. (1) also considers the role of SIRT1 in circadian clock, we regret not citing this work. However, we feel the inferences drawn in Furlan et al.'s (2) letter conflate 2 distinct studies with disparate purposes and methods. In Foteinou et al….
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The sui generis Sydney Brenner [Retrospectives]
Sydney Brenner died on April 5, 2019, at age 92. His fame arose from three domains in which he operated with uncommon intellectual vibrancy. First were his prescient ideas and breakthrough experiments that defined the DNA genetic code and how the information it contains is transmitted into proteins. Second, in…
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Identifying art forgeries by radiocarbon dating microgram quantities of artists' paints [Chemistry]
Most people view paintings orthogonally. Usually, this is what the artist intended. However, historically and technically minded artists, art conservators, technical art historians, and indeed forgers are also interested in what paintings look like in microscopic cross-section. From this vantage point, other dimensions of the art are revealed. The stratigraphic…
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Organic interfaces enhance strontium content of marine barite [Earth, Atmospheric, and Planetary Sciences]
The history of life and environmental change on Earth is told largely by physical and chemical indicators hosted within the sedimentary rock record. Barite (BaSO4) is one of the few minerals that is known to crystallize from seawater, and due to its relatively high chemical resiliency in nature, its trace…
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MZB1 folding and unfolding the role of IgA [Immunology and Inflammation]
The immune system sustains a continuous dialogue with the endogenous microbial communities residing at the mucosal surfaces, mediated by many factors, including IgA, the most abundant antibody isotype. In PNAS, Xiong et al. (1) explore the role of a B cell-specific factor in regulation of IgA secretion in the gut….
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Presynaptic NMDARs and astrocytes ally to control circuit-specific information flow [Neuroscience]
The entorhinal cortex (EC) conveys spatial, limbic, and sensory information to the hippocampus, which performs critical brain functions, including learning and memory processes and spatial information coding. Axons from superficial [layer (L)2] EC neurons make excitatory synapses onto granule cells (GCs) of the hippocampal dentate gyrus (DG), which prepare the…
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Reactive school closure weakens the network of social interactions and reduces the spread of influenza [Applied Physical Sciences]
School-closure policies are considered one of the most promising nonpharmaceutical interventions for mitigating seasonal and pandemic influenza. However, their effectiveness is still debated, primarily due to the lack of empirical evidence about the behavior of the population during the implementation of the policy. Over the course of the 2015 to…
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Regulation of nuclear architecture, mechanics, and nucleocytoplasmic shuttling of epigenetic factors by cell geometric constraints [Biophysics and Computational Biology]
Cells sense mechanical signals from their microenvironment and transduce them to the nucleus to regulate gene expression programs. To elucidate the physical mechanisms involved in this regulation, we developed an active 3D chemomechanical model to describe the three-way feedback between the adhesions, the cytoskeleton, and the nucleus. The model shows…
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Buckling and twisting of advanced materials into morphable 3D mesostructures [Engineering]
Recently developed methods in mechanically guided assembly provide deterministic access to wide-ranging classes of complex, 3D structures in high-performance functional materials, with characteristic length scales that can range from nanometers to centimeters. These processes exploit stress relaxation in prestretched elastomeric platforms to affect transformation of 2D precursors into 3D shapes…
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A hypothesis linking the energy demand of the brain to obesity risk [Anthropology]
The causes of obesity are complex and multifactorial. We propose that one unconsidered but likely important factor is the energetic demand of brain development, which could constrain energy available for body growth and other functions, including fat deposition. Humans are leanest during early childhood and regain body fat in later…
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Pak2 kinase promotes cellular senescence and organismal aging [Biochemistry]
Cellular senescence defines an irreversible cell growth arrest state linked to loss of tissue function and aging in mammals. This transition from proliferation to senescence is typically characterized by increased expression of the cell-cycle inhibitor p16INK4a and formation of senescence-associated heterochromatin foci (SAHF). SAHF formation depends on HIRA-mediated nucleosome assembly…
5h
Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases [Biochemistry]
Cyclic AMP (cAMP) phosphodiesterase-4 (PDE4) enzymes degrade cAMP and underpin the compartmentalization of cAMP signaling through their targeting to particular protein complexes and intracellular locales. We describe the discovery and characterization of a small-molecule compound that allosterically activates PDE4 long isoforms. This PDE4-specific activator displays reversible, noncompetitive kine
5h
SHOC2 complex-driven RAF dimerization selectively contributes to ERK pathway dynamics [Biochemistry]
Despite the crucial role of RAF kinases in cell signaling and disease, we still lack a complete understanding of their regulation. Heterodimerization of RAF kinases as well as dephosphorylation of a conserved "S259" inhibitory site are important steps for RAF activation but the precise mechanisms and dynamics remain unclear. A…
5h
Gating modules of the AMPA receptor pore domain revealed by unnatural amino acid mutagenesis [Biophysics and Computational Biology]
Ionotropic glutamate receptors (iGluRs) are responsible for fast synaptic transmission throughout the vertebrate nervous system. Conformational changes of the transmembrane domain (TMD) underlying ion channel activation and desensitization remain poorly understood. Here, we explored the dynamics of the TMD of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type iGluRs using genetically
5h
An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication [Cell Biology]
DNA damage-induced signaling by ATR and CHK1 inhibits DNA replication, stabilizes stalled and collapsed replication forks, and mediates the repair of multiple classes of DNA lesions. We and others have shown that ATR kinase inhibitors, three of which are currently undergoing clinical trials, induce excessive origin firing during unperturbed DNA…
5h
Genome-wide CRISPR screen identifies suppressors of endoplasmic reticulum stress-induced apoptosis [Cell Biology]
Sensing misfolded proteins in the endoplasmic reticulum (ER), cells initiate the ER stress response and, when overwhelmed, undergo apoptosis. However, little is known about how cells prevent excessive ER stress response and cell death to restore homeostasis. Here, we report the identification and characterization of cellular suppressors of ER stress-induced…
5h
PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension [Cell Biology]
Increased glycolysis in the lung vasculature has been connected to the development of pulmonary hypertension (PH). We therefore investigated whether glycolytic regulator 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (PFKFB3)-mediated endothelial glycolysis plays a critical role in the development of PH. Heterozygous global deficiency of Pfkfb3 protected mice from developing hypoxia-induced
5h
SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation [Cell Biology]
BRUCE/Apollon is a membrane-associated inhibitor of apoptosis protein that is essential for viability and has ubiquitin-conjugating activity. On initiation of apoptosis, the ubiquitin ligase Nrdp1/RNF41 promotes proteasomal degradation of BRUCE. Here we demonstrate that BRUCE together with the proteasome activator PA28γ causes proteasomal degradation of LC3-I and thus inhibits autophagy….
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HIF-1{alpha} is required for development of the sympathetic nervous system [Developmental Biology]
The molecular mechanisms regulating sympathetic innervation of the heart during embryogenesis and its importance for cardiac development and function remain to be fully elucidated. We generated mice in which conditional knockout (CKO) of the Hif1a gene encoding the transcription factor hypoxia-inducible factor 1α (HIF-1α) is mediated by an Islet1-Cre transgene…
5h
The constrained architecture of mammalian Hox gene clusters [Developmental Biology]
In many animal species with a bilateral symmetry, Hox genes are clustered either at one or at several genomic loci. This organization has a functional relevance, as the transcriptional control applied to each gene depends upon its relative position within the gene cluster. It was previously noted that vertebrate Hox…
5h
Plastic responses to novel environments are biased towards phenotype dimensions with high additive genetic variation [Evolution]
Environmentally induced phenotypes have been proposed to initiate and bias adaptive evolutionary change toward particular directions. The potential for this to happen depends in part on how well plastic responses are aligned with the additive genetic variance and covariance in traits. Using meta-analysis, we demonstrate that plastic responses to novel…
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MZB1 promotes the secretion of J-chain-containing dimeric IgA and is critical for the suppression of gut inflammation [Immunology and Inflammation]
IgA is the most abundantly produced antibody in the body and plays a crucial role in gut homeostasis and mucosal immunity. IgA forms a dimer that covalently associates with the joining (J) chain, which is essential for IgA transport into the mucosa. Here, we demonstrate that the marginal zone B…
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Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology [Immunology and Inflammation]
Resident fibroblasts at sites of infection, chronic inflammation, or cancer undergo phenotypic and functional changes to support leukocyte migration and, in some cases, aggregation into tertiary lymphoid structures (TLS). The molecular programming that shapes these changes and the functional requirements of this population in TLS development are unclear. Here, we…
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Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis [Immunology and Inflammation]
Lyme disease is a multisystem disorder caused by the spirochete Borrelia burgdorferi. A common late-stage complication of this disease is oligoarticular arthritis, often involving the knee. In ∼10% of cases, arthritis persists after appropriate antibiotic treatment, leading to a proliferative synovitis typical of chronic inflammatory arthritides. Here, we provide evidence…
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Direct delivery of adenoviral CRISPR/Cas9 vector into the blastoderm for generation of targeted gene knockout in quail [Agricultural Sciences]
Zygotes at the 1-cell stage have been genetically modified by microinjecting the CRISPR/Cas9 components for the generation of targeted gene knockout in mammals. In the avian species, genetic modification of the zygote is difficult because its unique reproductive system limits the accessibility of the zygote at the 1-cell stage. To…
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Solar thermal desalination as a nonlinear optical process [Applied Physical Sciences]
The ever-increasing global need for potable water requires practical, sustainable approaches for purifying abundant alternative sources such as seawater, high-salinity processed water, or underground reservoirs. Evaporation-based solutions are of particular interest for treating high salinity water, since conventional methods such as reverse osmosis have increasing energy requirements for higher c
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Spotting plants' microfilament morphologies and nanostructures [Applied Physical Sciences]
The tracheary system of plant leaves is composed of a cellulose skeleton with diverse hierarchical structures. It is built of polygonally bent helical microfilaments of cellulose-based nanostructures coated by different layers, which provide them high compression resistance, elasticity, and roughness. Their function includes the transport of water and nutrients from…
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Stability of the A15 phase in diblock copolymer melts [Applied Physical Sciences]
The self-assembly of block polymers into well-ordered nanostructures underpins their utility across fundamental and applied polymer science, yet only a handful of equilibrium morphologies are known with the simplest AB-type materials. Here, we report the discovery of the A15 sphere phase in single-component diblock copolymer melts comprising poly(dodecyl acrylate)−block−poly(lactide). A…
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The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells [Biochemistry]
The linear ubiquitin assembly complex (LUBAC) comprises 3 components: HOIP, HOIL-1, and Sharpin, of which HOIP and HOIL-1 are both members of the RBR subfamily of E3 ubiquitin ligases. HOIP catalyses the formation of Met1-linked ubiquitin oligomers (also called linear ubiquitin), but the function of the E3 ligase activity of…
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Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants [Biochemistry]
The synthetic auxin 2,4-dichlorophenoxyacetic acid (2,4-D) is an active ingredient of thousands of commercial herbicides. Multiple species of bacteria degrade 2,4-D via a pathway initiated by the Fe(II) and α-ketoglutarate (Fe/αKG)-dependent aryloxyalkanoate dioxygenases (AADs). Recently, genes encoding 2 AADs have been deployed commercially in herbicide-tolerant crops. Some AADs can also…
5h
Compartmentalized biosynthesis of mycophenolic acid [Biochemistry]
Mycophenolic acid (MPA) from filamentous fungi is the first natural product antibiotic to be isolated and crystallized, and a first-line immunosuppressive drug for organ transplantations and autoimmune diseases. However, some key biosynthetic mechanisms of such an old and important molecule have remained unclear. Here, we elucidate the MPA biosynthetic pathway…
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How the avidity of polymerase binding to the -35/-10 promoter sites affects gene expression [Biophysics and Computational Biology]
Although the key promoter elements necessary to drive transcription in Escherichia coli have long been understood, we still cannot predict the behavior of arbitrary novel promoters, hampering our ability to characterize the myriad sequenced regulatory architectures as well as to design new synthetic circuits. This work builds upon a beautiful…
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Nanoparticle-based local translation reveals mRNA as a translation-coupled scaffold with anchoring function [Biophysics and Computational Biology]
The spatial regulation of messenger RNA (mRNA) translation is central to cellular functions and relies on numerous complex processes. Biomimetic approaches could bypass these endogenous complex processes, improve our comprehension of the regulation, and allow for controlling local translation regulations and functions. However, the causality between local translation and nascent…
5h
Membrane perforation by the pore-forming toxin pneumolysin [Biophysics and Computational Biology]
Pneumolysin (PLY), a major virulence factor of Streptococcus pneumoniae, perforates cholesterol-rich lipid membranes. PLY protomers oligomerize as rings on the membrane and then undergo a structural transition that triggers the formation of membrane pores. Structures of PLY rings in prepore and pore conformations define the beginning and end of this…
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Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution [Cell Biology]
TMEM16K, a membrane protein carrying 10 transmembrane regions, has phospholipid scramblase activity. TMEM16K is localized to intracellular membranes, but whether it actually scrambles phospholipids inside cells has not been demonstrated, due to technical difficulties in studying intracellular lipid distributions. Here, we developed a freeze-fracture electron microscopy method that enabled us…
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Uncovering modern paint forgeries by radiocarbon dating [Chemistry]
Art forgeries have existed since antiquity, but with the recent rapidly expanding commercialization of art, the approach to art authentication has demanded increasingly sophisticated detection schemes. So far, the most conclusive criterion in the field of counterfeit detection is the scientific proof of material anachronisms. The establishment of the earliest…
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Anomalous phonon relaxation in Au333(SR)79 nanoparticles with nascent plasmons [Chemistry]
Research on plasmons of gold nanoparticles has gained broad interest in nanoscience. However, ultrasmall sizes near the metal-to-nonmetal transition regime have not been explored until recently due to major synthetic difficulties. Herein, intriguing electron dynamics in this size regime is observed in atomically precise Au333(SR)79 nanoparticles. Femtosecond transient-absorption spectroscopy revea
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Two deep-mantle sources for Paleocene doming and volcanism in the North Atlantic [Earth, Atmospheric, and Planetary Sciences]
The North Atlantic Igneous Province (NAIP) erupted in two major pulses that coincide with the continental breakup and the opening of the North Atlantic Ocean over a period from 62 to 54 Ma. The unknown mantle structure under the North Atlantic during the Paleocene represents a major missing link in…
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Rapid mixing and exchange of deep-ocean waters in an abyssal boundary current [Earth, Atmospheric, and Planetary Sciences]
The overturning circulation of the global ocean is critically shaped by deep-ocean mixing, which transforms cold waters sinking at high latitudes into warmer, shallower waters. The effectiveness of mixing in driving this transformation is jointly set by two factors: the intensity of turbulence near topography and the rate at which…
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Drainage network position and historical connectivity explain global patterns in freshwater fishes' range size [Ecology]
Identifying the drivers and processes that determine globally the geographic range size of species is crucial to understanding the geographic distribution of biodiversity and further predicting the response of species to current global changes. However, these drivers and processes are still poorly understood, and no ecological explanation has emerged yet…
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Opinion: The National Institutes of Health needs to better balance funding distributions among US institutions [Economic Sciences]
The NIH is the federal steward of biomedical research in the United States. Taxpayers fund the NIH; the NIH supports research into the underlying biology, etiology, and treatment of diseases; and benefits of that research are returned to taxpayers. This is a large and complex enterprise, but at its core…
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Social evolution leads to persistent corruption [Economic Sciences]
Cooperation can be sustained by institutions that punish free-riders. Such institutions, however, tend to be subverted by corruption if they are not closely watched. Monitoring can uphold the enforcement of binding agreements ensuring cooperation, but this usually comes at a price. The temptation to skip monitoring and take the institution's…
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Organic-mineral interfacial chemistry drives heterogeneous nucleation of Sr-rich (Bax, Sr1-x)SO4 from undersaturated solution [Environmental Sciences]
Sr-bearing marine barite [(Bax, Sr1−x)SO4] cycling has been widely used to reconstruct geochemical evolutions of paleoenvironments. However, an understanding of barite precipitation in the ocean, which is globally undersaturated with respect to barite, is missing. Moreover, the reason for the occurrence of higher Sr content in marine barites than expected…
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Polar bear evolution is marked by rapid changes in gene copy number in response to dietary shift [Evolution]
Polar bear (Ursus maritimus) and brown bear (Ursus arctos) are recently diverged species that inhabit vastly differing habitats. Thus, analysis of the polar bear and brown bear genomes represents a unique opportunity to investigate the evolutionary mechanisms and genetic underpinnings of rapid ecological adaptation in mammals. Copy number (CN) differences…
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Complete reconstitution of bypass and blocking functions in a minimal artificial Fab-7 insulator from Drosophila bithorax complex [Genetics]
Boundaries in the bithorax complex (BX-C) delimit autonomous regulatory domains that drive parasegment-specific expression of the Hox genes Ubx, abd-A, and Abd-B. The Fab-7 boundary is located between the iab-6 and iab-7 domains and has two key functions: blocking cross-talk between these domains and at the same time promoting communication…
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A symmetric geometry of transmembrane domains inside the B cell antigen receptor complex [Immunology and Inflammation]
B lymphocytes have the ability to sense thousands of structurally different antigens and produce cognate antibodies against these molecules. For this they carry on their surface multiple copies of the B cell antigen receptor (BCR) comprising the membrane-bound Ig (mIg) molecule and the Igα/Igβ heterodimer functioning as antigen binding and…
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Outflanking immunodominance to target subdominant broadly neutralizing epitopes [Immunology and Inflammation]
A major obstacle to vaccination against antigenically variable viruses is skewing of antibody responses to variable immunodominant epitopes. For influenza virus hemagglutinin (HA), the immunodominance of the variable head impairs responses to the highly conserved stem. Here, we show that head immunodominance depends on the physical attachment of head to…
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Evidence for a vestigial nematic state in the cuprate pseudogap phase [Physics]
The CuO2 antiferromagnetic insulator is transformed by hole-doping into an exotic quantum fluid usually referred to as the pseudogap (PG) phase. Its defining characteristic is a strong suppression of the electronic density-of-states D(E) for energies |E| < Δ*, where Δ* is the PG energy. Unanticipated broken-symmetry phases have been detected…
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Topology on a new facet of bismuth [Physics]
Bismuth-based materials have been instrumental in the development of topological physics, even though bulk bismuth itself has been long thought to be topologically trivial. A recent study has, however, shown that bismuth is in fact a higher-order topological insulator featuring one-dimensional (1D) topological hinge states protected by threefold rotational and…
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Shaping the branched flow of light through disordered media [Physics]
Electronic matter waves traveling through the weak and smoothly varying disorder potential of a semiconductor show a characteristic branching behavior instead of a smooth spreading of flow. By transferring this phenomenon to optics, we demonstrate numerically how the branched flow of light can be controlled to propagate along a single…
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Experimental evidence on promotion of electric and improved biomass cookstoves [Sustainability Science]
Improved cookstoves (ICS) can deliver "triple wins" by improving household health, local environments, and global climate. Yet their potential is in doubt because of low and slow diffusion, likely because of constraints imposed by differences in culture, geography, institutions, and missing markets. We offer insights about this challenge based on…
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Last chlamydia-free koala population may safeguard future of species
The last, large, isolated, healthy chlamydia-free population of koalas in Australia may have been identified on Kangaroo Island, said Morris Animal Foundation-funded researchers at the University of Adelaide.
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New study shows nanoscale pendulum coupling
In 1665, Lord Christiaan Huygens found that two pendulum clocks, hung in the same wooden structure, oscillated spontaneously and perfectly in line but in opposite directions: the clocks oscillated in anti-phase. An article published in the journal Physical Review Letters -led by researchers from the University of Barcelona showed a nanoscale version of mechanic oscillators.
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Fast radio burst pinpointed to distant galaxy
In a rare feat, astronomers have pinpointed the place of origin of a fast radio burst, with a surprising outcome.
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Methane vanishing on Mars: Researchers propose new mechanism as an explanation
The processes behind the release and consumption of methane on Mars have been discussed since methane was measured for the first time for approximately 15 years ago. Now, an interdisciplinary research group from Aarhus University has proposed a previously overlooked physical-chemical process that can explain methane's consumption.
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Redefining the limits of measurement accuracy
For centuries, humans have been expanding their understanding of the world through more and more precise measurement of light and matter. Today, quantum sensors achieve extremely accurate results. An example of this is the development of atomic clocks, which are expected to neither gain nor lose more than a second in thirty billion years. Gravitational waves were detected via quantum sensors as we
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The world's first high-intensity laser pulses shaped like a corkscrew
University of California San Diego researchers have calculations for how to create high-intensity twisted laser beams—a flavor of laser pulse the world has likely never seen. These researchers also have done the math on how to use these corkscrew shaped laser pulses to do cutting-edge research. Finally, they have predictions on how the materials that they plan to "drill" into with corkscrew light
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How to Help Your Dog Stay Calm During Fireworks
How to Help Your Dog Stay Calm During Fireworks A survey of 1,225 dog owners reveals what works and what doesn't to help dogs with firework fear. 00-frightened-dog_cropped.jpg Image credits: Evdoha_spb/ Shutterstock Culture Tuesday, July 2, 2019 – 11:45 Nala Rogers, Staff Writer (Inside Science) — For many dogs, the Fourth of July is less a celebration than a night of agonizing terror. But there
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How Americans Decided Dogs Can't Eat Grains
Although she is very special to me, Midge, my three-year-old rescue Chihuahua, is not all that special in general. She's the average weight for her size. She has no known medical problems, besides anxiety, which is probably rational given that she's eight inches tall. Nothing I've ever fed her has seemed to irritate her tiny little tummy. Nevertheless, I feed her only grain-free dog food. The kin
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Millet farmers adopted barley agriculture and permanently settled the Tibetan Plateau
The permanent human occupation on the Tibetan Plateau was facilitated by the introduction of cold-tolerant barley around 3600 years before present (BP), however, how barley agriculture spread onto the Tibetan Plateau remains unknown. Now by using both genetics and archaeological data, researchers from Kunming Institute of Zoology, CAS and Lanzhou University revealed that barley agriculture was mai
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A new path to understanding second sound in Bose-Einstein condensates
There are two sound velocities in a Bose-Einstein condensate. In addition to the normal sound propagation there is second sound, which is a quantum phenomenon. Scientists in Ludwig Mathey's group from the University of Hamburg have put forth a new theory for this phenomenon.
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Perceived threats to family increases women's willingness to sacrifice during war
Researchers at the Universities of Turku and Helsinki found that women were more likely to volunteer for all-female paramilitary organizations if they had brothers or husbands who were currently serving in the military. This result suggests that bonding with larger and frequently imagined communities, such as the nation state or religious groups, can arise from psychology mechanisms designed by ev
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Equations help predict the behavior of water in rivers
River dikes are small dams made of earth that are used to hold in the water of the course of a river, without affecting the course too much. However, when the water exceeds a certain level due to flooding, the dike breaks, causing disasters that can be devastating for human life or cause huge financial losses.
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The secret of mushroom colors
The fly agaric with its red hat is perhaps the most evocative of the diverse and variously colored mushroom species. Hitherto, the purpose of these colors was shrouded in mystery. Researchers at the Technical University of Munich (TUM), in collaboration with the Bavarian Forest National Park, have now put together the first pieces of this puzzle.
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The secret of mushroom colors
The fly agaric with its red hat is perhaps the most evocative of the diverse and variously colored mushroom species. Hitherto, the purpose of these colors was shrouded in mystery. Researchers at the Technical University of Munich (TUM), in collaboration with the Bavarian Forest National Park, have now put together the first pieces of this puzzle.
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Remote but remarkable: Illuminating the smallest inhabitants of the largest ocean desert
The South Pacific Gyre is an ocean desert. However, due to its vast size the microbial inhabitants of the South Pacific Gyre contribute significantly to global biogeochemical cycles. In an unparalleled investigation, scientists from the Max Planck Institute for Marine Microbiology in Bremen, Germany, have now made a comprehensive inventory of the microbial community of the South Pacific Gyre. This
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Japan's return to commercial whaling has no economic or cultural case
The decision by Japan to resume commercial whaling should be condemned – if not for its uncertain effect on whales, then for its contempt for international agreements
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Promising approach: Prevent diabetes with intermittent fasting
Intermittent fasting is known to improve sensitivity to the blood glucose-lowering hormone insulin and to protect against fatty liver. DZD scientists from DIfE have now discovered that mice on an intermittent fasting regimen also exhibited lower pancreatic fat. In their current study published in the journal Metabolism, the researchers showed the mechanism by which pancreatic fat could contribute
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Physicists OK commercial graphene for T-wave detection
Russian researchers from the Moscow Institute of Physics and Technology (MIPT) and Valiev Institute of Physics and Technology have demonstrated resonant absorption of terahertz radiation in commercially available graphene. This is an important step toward designing efficient terahertz detectors, which would enable faster internet and a safe replacement for X-ray body scans.
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Tiny motor can 'walk' to carry out tasks
MIT researchers have assembled microrobots from a small set of standardized components, as a step toward self-replicating systems.
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The new racial disparity in special education
Racial disparity in special education is growing, and it's more complex than previously thought. New research from Michigan State University examined how often black and Hispanic students are identified as needing special education compared to white students, leading to new findings on disproportionality and racial gaps.
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Methane vanishing on Mars: Danish researchers propose new mechanism as an explanation
Wind-driven erosion of minerals on Mars may be the reason why methane disappears so rapidly on the red planet. Saltation causes electrical charges, that can oxidize minerals and ionize gases like methane, making the ionized methane bond to the minerals. That is the explanation proposed by an interdisciplinary research group from Aarhus University, based on laboratory experiments in a Mars-like env
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Concussion rates are nearly double what we thought — and summer is prime injury time
Canada's largest-ever concussion study, led by researchers at Toronto Rehab, has uncovered rates that are nearly double what has previously been recorded, showcasing the need for increased education about concussion and access to more specialized, best-in-practice concussion care.
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NASA's Orion Crew Capsule Aced Its Abort System Test
Orion Exit Strategy Before NASA can attempt to send astronauts back to the Moon, it needs to know they have a way to GTFO of harm's way if something goes wrong during the trip. To that end, the space agency tested its Orion spacecraft's Launch Abort System (LAS) on Tuesday — and it seems NASA's astronaut escape plan works exactly as hoped. Mission Aborted To start the three-minute-long Ascent Abo
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Robots that are not quite life-like: 'Uncanny valley' in the brain
Scientists have identified mechanisms in the human brain that could help explain the phenomenon of the 'Uncanny Valley' — the unsettling feeling we get from robots and virtual agents that are too human-like. They have also shown that some people respond more adversely to human-like agents than others.
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Facebook acts on 'sensational' health cures after report
Facebook and YouTube said Tuesday they were moving to reduce the spread of misleading health care claims after a media report showed the proliferation of bogus cancer cures on social media.
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Microsoft goes back in time with the 'all-new' Windows 1.0
Accompanying the teaser is short 13-second video that spans through the Windows logos in reverse chronological order, from Windows 10 back through Windows 1.0. Fittingly, it is set to a catchy …
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Why some cities turn off the water pipes at night
For more than a billion people around the world, running water comes from water systems that turn on and off at certain times. A new paper by University of Toronto Engineering professor David Taylor proposes a model to explain why and how these systems come to be — and how they fit into meeting international targets for human development and safe drinking water.
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Personalized medicine software vulnerability uncovered by Sandia researchers
A weakness in one common open source software for genomic analysis left DNA-based medical diagnostics vulnerable to cyberattacks. Researchers at Sandia National Laboratories identified the weakness and notified the software developers, who issued a patch to fix the problem. The issue has also been fixed in the latest release of the software, and no attack from this vulnerability is known.
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Physical and mental illnesses combined increase ED visits
Canadian study suggests the reasons are both physical and social. Paul Biegler reports.
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This brain region may be why some robots send chills down your spine
Scientists may have traced the source of the "uncanny valley" sensation in the brain.
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'What Would You Do If We Found Aliens?' Survey Asks
If you find out we are not alone in the universe, how would you respond?
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A Bulwark against Trump's Stem Cell Ban
California's Institute for Regenerative Medicine, a kind of mini-NIH, does crucial basic research without federal funding — Read more on ScientificAmerican.com
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Study: Brain injury common in domestic violence
Domestic violence survivors commonly suffer repeated blows to the head and strangulation, trauma that has lasting effects that should be widely recognized by advocates, health care providers, law enforcement and others who are in a position to help, according to the authors of a new study.
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Atmosphere of mid-size planet revealed by hubble and spitzer
Two NASA space telescopes have teamed up to identify, for the first time, the detailed chemical 'fingerprint' of a planet between the sizes of Earth and Neptune. No planets like this can be found in our own solar system, but they are common around other stars.
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Researchers clock DNA's recovery time after chemotherapy
A team of researchers found that DNA damaged by the widely used chemotherapy drug cisplatin is mostly good as new in noncancerous tissue within two circadian cycles, or two days. The results could inform the development of chronochemotherapies — strategies aimed at administering chemotherapy drugs at times that maximize tumor damage while minimizing side effects.
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Catheters: Big source of infection, but often overlooked
Indwelling devices like catheters cause roughly 25% of hospital infections, but ongoing efforts to reduce catheter use and misuse haven't succeeded as much as health care workers would like.
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Blood pressure self-monitoring helps get patients with hypertension moving, study says
Using blood pressure self-monitoring is an effective way to empower patients with hypertension to stick with an exercise program, according to a first-of-its-kind study conducted by a multidisciplinary team of researchers.
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What makes a good excuse work? A philosopher may have the answer
The things we appeal to when making excuses are myriad: tiredness, stress, a looming work deadline, a wailing infant. But what do these various excuses have in common that allows us to recognize them all as plausible? A researcher has suggested that the answers lie in what they all tell us about our underlying motivation. When excuses are permissible, it's because they show that while we acted wro
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Robots that are not quite life-like: 'Uncanny valley' in the brain
Scientists have identified mechanisms in the human brain that could help explain the phenomenon of the 'Uncanny Valley' — the unsettling feeling we get from robots and virtual agents that are too human-like. They have also shown that some people respond more adversely to human-like agents than others.
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Genomic warning flag just in time for beach season: Jellyfish toxins
A new article might make you squirm if you plan to hit the beach. This article presents the draft genomes of three jellyfish species, which have a range of physical traits and level of toxicity. Jellyfish kill more people than sharks, stingrays, and sea snakes combined; thus, having sequences and their analyses available provides an essential resource for future investigation of toxin gene evoluti
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A Bulwark against Trump's Stem Cell Ban
California's Institute for Regenerative Medicine, a kind of mini-NIH, does crucial basic research without federal funding — Read more on ScientificAmerican.com
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Make a Splash with Citizen Science
This summer, whether you're at home, fishing on a lake, or walking along the beach, consider getting involved in one or more of the citizen science projects featured below. Each one empowers us to keep an eye on the health of our water sources. Cheers! The SciStarter Team Stream Selfie More than one-third of us drink water that runs through streams. But how clean are those streams? To find out, we
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NASA's Orion Successfully Completes Final Major Flight Test
The crew capsule and its launch abort safety system lifted off on time from Cape Canaveral. (Credit: NASA) On Tuesday morning at 7am EDT, NASA successfully completed the final major flight test for their Orion crew capsule. This is the new craft NASA will use to transport humans to the Moon and Mars as a new age of space exploration begins. The Artemis Moon mission is slated to begin next year wit
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Cockroaches are evolving to a point where theyâll be nearly impossible to kill
submitted by /u/ILOVEASIANCUNTS [link] [comments]
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Antarctic sea ice: Shrinks to record low levels, study says
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Researchers create worldwide solar energy model
submitted by /u/V2O5 [link] [comments]
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AI classifies people's emotions from the way they walk
submitted by /u/izumi3682 [link] [comments]
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Many Websites Are Down Because Of Major Cloudflare Outage
Your browser may have thrown up the "502 Bad Gateway" error if you have been trying to access some websites this morning. Quite a few have been affected by a massive Cloudflare …
6h
A tiny jellyfish robot could swim inside the bladder to deliver drugs
A tiny jellyfish-like robot could be used to deliver drugs in the body. It is only 3 millimeters across and is controlled by magnetic fields
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Dose-dependent effects of esmolol-epinephrine combination therapy in myocardial ischemia
Animal studies on cardiac arrest found that a combination of epinephrine with esmolol attenuates post-resuscitation myocardial dysfunction. Based on these findings, the researchers hypothesized that esmololepinephrine combination therapy would be superior to a reported cardioprotective esmolol therapy alone in a mouse model of myocardial ischemia and reperfusion (IR) injury.
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Getting more heat out of sunlight
An aerogel material developed at MIT can generate heat of more than 200 degrees celsius from sunlight, without the need for mirrors or vacuum tubes.
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Proteins trapped in glass could yield new medicinal advances
Researchers at Chalmers University of Technology, Sweden, have developed a unique method for studying proteins which could open new doors for medicinal research. Through capturing proteins in a nano-capsule made of glass, the researchers have been able to create a unique model of proteins in natural environments. The results are published in the scientific journal, Small.
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Quick Roundup of Monthly Science Stories
Quick Roundup of Monthly Science Stories A month's worth of cool science stories summed up: Saturn's rings, space sperm, better blood donation, and puppy dog eyes. Saturn's Rings, Space Sperm, Better Blood Donation, and Puppy Dog Eyes (June 2019 Monthly Roundup) Video of Saturn's Rings, Space Sperm, Better Blood Donation, and Puppy Dog Eyes (June 2019 Monthly Roundup) On this monthly roundup
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A tiny jellyfish robot could swim inside the bladder to deliver drugs
A tiny jellyfish-like robot could be used to deliver drugs in the body. It is only 3 millimeters across and is controlled by magnetic fields
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Have mice really been cured of HIV using CRISPR gene editing?
Some mice receiving a therapy that includes CRISPR gene editing appear to have been cured of HIV, but safety concerns must be overcome before human trials
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Australia continues to see steady drop in new HIV infections
Subsidized access to preventative drugs helping curb infections
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Decoding the Language of Neurons
A new study reveals surprising variations in the neural code — Read more on ScientificAmerican.com
6h
Decoding the Language of Neurons
A new study reveals surprising variations in the neural code — Read more on ScientificAmerican.com
6h
Bench to beside study of a targetable enzyme controlling aggressive prostate cancer
Prostate cancer represents a major health challenge and there is currently no effective treatment once it has advanced to the aggressive, metastatic stage. A new has revealed a key cellular mechanism that contributes to aggressive prostate cancer, and supporting a new clinical trial.
6h
Doctors need nutrition education, says commentary in JAMA Internal Medicine
Overweight, diabetes, heart disease, and many forms of cancer are driven by unhealthful diets, but most doctors do not have the knowledge to turn this problem around.
6h
UH researcher reports the way sickle cells form may be key to stopping them
University of Houston chemist Vassiliy Lubchenko is reporting a new finding in Nature Communications on how sickle cells are formed, which may lead not only to stopping their formation, but to new avenues for making uniformly-sized nanoparticles for industry.
6h
DNA from tooth in Florida man's foot solves 25-year-old shark bite mystery
In 2018, a Florida man found a piece of tooth embedded in his foot from a shark bite off Flagler Beach 24 years earlier. A DNA test of the tooth, conducted by scientists at the Florida Museum of Natural History, revealed the kind of shark that had nabbed his foot nearly a quarter century ago: a blacktip.
6h
High brightness mid-infrared laser expands horizon of spectroscopic analytical technique
Researchers have used an extremely bright mid-infrared laser to perform an analytical technique known as spectroscopic ellipsometry. The new approach captures high-resolution spectral information in less than a second and could offer new insights into quickly changing properties of a variety of samples from plastics to biological materials.
6h
Creating 'movies' of thin film growth at NSLS-II
Researchers from the University of Vermont, Boston University, and Brookhaven National Laboratory have demonstrated a new experimental capability for watching thin film growth in real-time. Using the National Synchrotron Light Source II, the researchers were able to produce a 'movie' of thin film growth that depicts the process more accurately than traditional techniques can.
6h
Novel computer model supports cancer therapy
Researchers from the Life Sciences Research Unit (LSRU) of the University of Luxembourg have developed a computer model that simulates the metabolism of cancer cells. They used the programme to investigate how combinations of drugs could be used more effectively to stop tumour growth. The biologists now published their findings in the scientific journal EBioMedicine of the prestigious Lancet group
6h
New chemical tools to modify and study biomolecules
EPFL chemists have developed new tools to modify sulfur-containing biomolecules, from simple amino acids to large protein complexes such as nucleosomes. These modifications then provide attachment points for two new functional groups, enabling studies of biochemical interactions on the single-molecule level.
6h
Antibiotics weaken flu defenses in the lung
Antibiotics can leave the lung vulnerable to flu viruses, leading to significantly worse infections and symptoms, finds a new study in mice led by the Francis Crick Institute.The research, published in Cell Reports, discovered that signals from gut bacteria help to maintain a first line of defense in the lining of the lung. When mice with healthy gut bacteria were infected with the flu, around 80%
6h
Arts and medicine: clarifying history, lessons for today from Peter Neubauer's twins study
This Arts and Medicine feature reviews 'Three Identical Strangers' and 'The Twinning Reaction,' two documentaries telling the story of identical twins and triplets adopted as infants into separate families who were unknowing participants in a two-decade nature vs. nurture study of child development beginning in 1960.
6h
Statewide action in California associated with decrease in kindergartners entering school without up-to-date vaccines
Legislative and administrative actions by the state of California were associated with a decrease in the rate of kindergartners entering school without up-to-date vaccinations.
6h
The neuroscience of autism: New clues for how condition begins
UNC School of Medicine scientists found that a gene mutation linked to autism normally works to organize the scaffolding of brain cells called radial progenitors necessary for the orderly formation of the brain. The discovery, published in Neuron, illuminates details of a key process in brain development and adds to the scientific understanding of the biological basis of autism spectrum disorder (
6h
HIV eliminated from the genomes of living animals
In a major collaborative effort, researchers at the Lewis Katz School of Medicine at Temple University and the University of Nebraska Medical Center (UNMC) have for the first time eliminated replication-competent HIV-1 DNA — the virus responsible for AIDS — from the genomes of living animals. The study, reported online July 2 in the journal Nature Communications, marks a critical step toward the
6h
Gut microbes protect against flu virus infection in mice
Commensal gut microbes stimulate antiviral signals in non-immune lung cells to protect against the flu virus during early stages of infection, researchers report July 2 in the journal Cell Reports. Enhanced baseline type I interferon (IFNα/β) signaling, which drives antiviral responses, reduced flu virus replication and weight loss in mice, but this protective effect was attenuated by antibiotic t
6h
Innate immune responses to high-fat diets lead to obesity
Why is eating a high fat diet a recipe for obesity? According to a new study from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan, the answer involves the activity of a specific type of immune cell that lives in the small intestine. Experiments showed that without group-2 innate lymphoid cells (ILC2s) in the small intestines, mice can eat high-fat diets without gaining extra weigh
6h
DNA changes made us 'the fat primates'
Long before the modern obesity epidemic, evolution made us fat. "We're the fat primates," says Devi Swain-Lenz, a postdoctoral associate in biology at Duke University. The fact that humans are chubbier than chimpanzees isn't news to scientists, but new evidence could help explain how we got that way. Despite having nearly identical DNA sequences, chimps and early humans underwent critical shifts
6h
New chemical tools to modify and study biomolecules
Understanding the structure and metabolism of cells and living organisms is essential for the development of new drugs and diagnostics. The availability of chemical tools that allow scientists to edit biomolecules, like proteins, with atom-level resolution have greatly contributed to the progress of chemical biology.
6h
Carbohydrate in the heart regulates blood pressure
A particular type of carbohydrate plays an important role in regulating the blood pressure in the human body, according to new research in rats. The researchers believe that the finding may have the potential to improve medications for high blood pressure. Both hypertension and hypotension can have adverse health consequences and lead to cardiovascular diseases and syncope, respectively. "It may
6h
A jellyfish, but not…
Scientists find marine inspiration for a multi-functional robots.
6h
This Radical New DNA Microscope Reimagines the Cellular World
It's not every day that something from the 17 th century gets radically reinvented. But this month, a team from the Broad Institute at MIT and Harvard took aim at one of the most iconic pieces of lab ware—the microscope—and tore down the entire concept to recreate it from scratch. I'm sure you have a mental picture of a scope: a stage to put samples on, a bunch of dials to focus the image, tunnel
6h
The world needs a global agenda for sand
Sand is a key ingredient in the recipe of modern life, and yet it is being extracted faster than it can be replaced.
6h
New study challenges claim that exogenous RNA is essential for sperm function
Scientists from the University of Bath are challenging the claims of two high profile papers from 2018 which reported that in the mouse, RNA has to be added to sperm for them to be fully fertile. The Bath findings undermine a proposed mechanism of epigenetic inheritance in which offspring inherit traits acquired by their parents.
6h
Measuring the laws of nature
One of the fundamental physical constants, the 'weak axial vector coupling constant' (gA), has now been measured with very high precision for the first time. It is needed to explain nuclear fusion in the sun, to understand the formation of elements shortly after the Big Bang, or to understand important experiments in particle physics. With the help of sophisticated neutron experiments, the value o
6h
Remote but remarkable: Illuminating the smallest inhabitants of the largest ocean desert
The South Pacific Gyre is an ocean desert. However, due to its vast size the microbial inhabitants of the South Pacific Gyre contribute significantly to global biogeochemical cycles. In an unparalleled investigation, scientists from the Max Planck Institute for Marine Microbiology in Bremen, Germany, have now made a comprehensive inventory of the microbial community of the South Pacific Gyre. This
6h
The secret of mushroom colors
The fly agaric with its red hat is perhaps the most evocative of the diverse and variously colored mushroom species. Hitherto, the purpose of these colors was shrouded in mystery. Researchers at the Technical University of Munich (TUM), in collaboration with the Bavarian Forest National Park, have now put together the first pieces of this puzzle.
6h
Carbohydrate in the heart seems to help regulate blood pressure
New research suggests that a particular type of carbohydrate plays an important role in regulating the blood pressure in the human body. This has been shown by researchers from the University of Copenhagen and Rigshospitalet in a new study using rats. The researchers believe that the finding may have a vast potential for improved medications for high blood pressure.
6h
Holy crocodiles
Sebastian Brackhane of the University of Freiburg has researched the cultural status of the reptiles in East Timor.
6h
Tweeting while watching TV diminishes enjoyment
The most significant impact of two-screen experience was on viewers' ability to 'transport' into the narrative and become immersed in the televised story.
6h
Parasitology — On filaments and fountains
Microbiologists at Ludwig-Maximilians-Universitaet (LMU) in Munich have shown that Toxoplasma gondii, the parasite that is responsible for toxoplasmosis, utilizes at least two modes of locomotion during its infection cycle.
6h
FEFU scientists teamed up with colleagues to develop ointment for skin cancer prevention
Scientists from Far Eastern Federal University (FEFU), V.I. Vernadsky Crimean Federal University, Dmitry Mendeleev University of Chemical Technology, and Far Eastern Branch of the Russian Academy of Sciences (FEB RAS), assumed the risks of primary skin cancer and its recurrences can be significantly reduced by applying the ointment with antisense oligonucleotides which are short DNA, RNA fragments
6h
California's new vaccine rules kept more kindergartners up-to-date
Three statewide interventions improved the rates of kindergartners behind on required vaccinations in California, researchers report.
6h
Smart glasses follow our eyes and focus automatically – By using eye-tracking technology to automatically control a pair of autofocus lenses, engineers have created a prototype for "autofocals" designed to restore proper vision in people who would ordinarily need progressive lenses.
submitted by /u/quantumcipher [link] [comments]
6h
Empathic AI could be the next stage in human evolution – if we get it right – Designing human-centric AI interactions, optimized to develop trusted relationships between AI and humans, presents the largest opportunity for human and societal advancement in the modern era.
submitted by /u/gone_his_own_way [link] [comments]
6h
Random Surfaces Hide an Intricate Order
In Raiders of the Lost Ark , Indiana Jones must find a secret chamber that contains the legendary Ark of the Covenant. To identify its exact location, Indy must uncover a special map that's only visible when the sun shines through a special crystal in a certain room at a certain time of day. This idea — that essential information can be revealed when circumstances are just right — occurs in many
6h
This Jellyfish Robot Is Much More Than Just a Good Swimmer
At less than a quarter inch across, the magnetically activated robot can manipulate water flow to manipulate objects.
7h
New chemical tools to modify and study biomolecules
Understanding the structure and metabolism of cells and living organisms is essential for the development of new drugs and diagnostics. The availability of chemical tools that allow scientists to edit biomolecules, like proteins, with atom-level resolution have greatly contributed to the progress of chemical biology.
7h
Daily briefing: There are already too many power plants
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02067-9 Existing power plants must be shut down or retrofitted to limit global warming, time is running out for sand, and how to support open-source software and stay sane.
7h
'Psychological fear': MIT scientists of Chinese origin protest toxic US climate
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02063-z Researchers describe how a government crackdown on foreign influence is affecting them following a statement of support from their university.
7h
A fast radio burst localized to a massive galaxy
Nature, Published online: 02 July 2019; doi:10.1038/s41586-019-1389-7 A fast radio burst localized to a massive galaxy
7h
As the World Heats Up, Soccer Must Adapt
Players face higher health risks, while the timing and location of may change — Read more on ScientificAmerican.com
7h
Redefining the limits of measurement accuracy
Scientists at the QUEST Institute at Leibniz University, Hannover, and the Physikalisch-Technische Bundesanstalt, have, together with colleagues in Florence, Italy, introduced a method based on a non-classical state adapted to two measurement parameters at once. This will enable precision measurements of molecules which could reveal interactions between conventional and dark matter. They report on
7h
Glow reveals dangerous bacteria
Salmonella and listeria are among the most widely distributed and deadliest causes of foodborne infections. Their rapid and reliable detection on food and industrial food processing equipment is very important. In the journal Angewandte Chemie, scientists have introduced a new, ultrasensitive, chemiluminescence-based method for the direct detection of Salmonella and Listeria monocytogenes. Because
7h
Long-term follow up is required to help maintain bone health in childhood cancer survivors
A new publication by the IOF Cancer and Bone Working Group provides succinct recommendations for essential long-term follow-up of bone health in childhood cancer survivors. It aims to help clinicians define specific groups at higher risk of long-term bone complications, identify unrecognized long-term adverse effects, and ultimately improve patient care. It includes a concise diagnostic-therapeuti
7h
Researchers identify maximum weight children should carry in school backpacks
Scientists from the University of Granada and Liverpool John Moores University (UK) have established that school children who use backpacks should avoid loads of more than 10% of their body weight — and those who use trolleys, 20% of their body weight.
7h
Generation and sampling of quantum states of light in a silicon chip
Scientists from the University of Bristol and the Technical University of Denmark have found a promising new way to build the next generation of quantum simulators combining light and silicon micro-chips.
7h
The Shocking Falling-Out Between Taylor Swift and a Longtime Ally
Scott Borchetta is widely recognized as the man who made Taylor Swift's career by signing, in 2006, the then-15-year-old unknown singer. But it could also be said that Swift made Borchetta's career. In 2005, the Nashville record exec left DreamWorks Records "to roll all the dice," as he later put it , and start a new label, Big Machine Records, with just three artists: Jack Ingram, Danielle Peck,
7h
Space traffic is our next wicked environmental problem | Moriba Jah
"Most of what we send into outer space never comes back," says astrodynamicist and TED Fellow Moriba Jah. In this forward-thinking talk, Jah describes the space highways orbiting earth and how they're mostly populated by space junk. Learn more about his quest to develop and scale the world's first crowdsourced space traffic monitoring system — and how it could help solve the debris problem in nea
7h
The Simple Way Apple and Google Let Domestic Abusers Stalk Victims
To prove a point about common location-sharing apps, I asked my wife to use them to spy on me.
7h
'Spaceteam' Is a Frantic Sci-fi Card Game That Makes Dying in Outer Space Fun!
If you saw the movie Alien , or any of its sequels, you know what happens when you're marooned in space and you don't work together as a team. Cooperation is key in all dangerous environments, and that's especially true in a malfunctioning spaceship. And that's pretty much the entire premise behind Spaceteam, a fast-paced, a science-fiction-themed cooperative card game . Spaceteam is an adaptatio
7h
The Atlantic Hires Linzee Troubh as Development Director for Film and TV
The Atlantic announced today the hire of Linzee Troubh as development director, a new role that will oversee the development of scripted and unscripted content from The Atlantic's journalism, past and present. Troubh will support a recently announced first-look deal between The Atlantic and Anonymous Content; she will assist in the development of creative material optioned through the multi-year
7h
AT&T down: 911 calls failing to go through amid major carrier outage
Mobile phone users advised to use landlines to contact police or ambulance services
7h
New Method for Tackling Stroke Restrains an Overactive Immune System
Shutting down an inflammatory molecule could potentially provide treatment days after onset — Read more on ScientificAmerican.com
7h
People often wrongly assume that a situation is zero-sum, meaning that for someone to gain something someone else must lose something equivalent, even when that's not the case. This can be an issue, for example, when it leads people to oppose policies that will help members of other social groups.
submitted by /u/randomusefulbits [link] [comments]
7h
What the Men Can Learn From the Women at Wimbledon
On the first day of play at the 2019 edition of Wimbledon, three remarkably talented players under the age of 23 suffered upsets. In the women's draw, 21-year-old Naomi Osaka, currently ranked No. 2 in the world, lost in straight sets to Yulia Putintseva, the same player who defeated Osaka a little less than two weeks ago at the Birmingham Classic . On the men's side, both 22-year-old Alexander Z
7h
Scientists weigh the balance of matter in galaxy clusters
A method of weighing the quantities of matter in galaxy clusters – the largest objects in our universe – has shown a balance between the amounts of hot gas, stars and other materials.
7h
Using a common anticonvulsant to counteract inflammation
The interaction between a chromosomal protein called HMGB1 and a cellular receptor called RAGE is known to trigger inflammation. Researchers from Tokyo University of Science have now used computer software to analyze structural similarities among existing drugs, and discovered that the popular anticonvulsant drug papaverine blocks the binding of HMGB1 to RAGE. The researchers conclude that papaver
7h
Study probes how to tell elderly patients not to bother with cancer screening
Over the past decades, the idea that all adults should get regularly screened for cancer — with mammograms, colonoscopies and prostate specific antigen blood tests — has been conveyed to the public time after time. But current clinical guidelines recommend against screening many older adults, such as those with less than 10 years' life expectancy. For doctors, talking to a patient about the idea
7h
Millet farmers adopted barley agriculture and permanently settled the Tibetan Plateau
The permanent human occupation on the Tibetan Plateau was facilitated by the introduction of cold-tolerant barley around 3600 years before present, however, how barley agriculture spread onto the Tibetan Plateau remains unknown. Researchers revealed that the barley agriculture was mainly brought onto the plateau by the millet farmers from northern China. Moreover, the genetic contribution from mil
7h
A new path to understanding second sound in Bose-Einstein condensates
There are two sound velocities in a Bose-Einstein condensate. In addition to the normal sound propagation there is second sound, which is a quantum phenomenon. Scientists around Ludwig Mathey from the University of Hamburg have put forth a new theory for this phenomenon.
7h
Misjudging the strength of other people's emotions based on egocentric bias
People of all ages tend to misjudge the strength of other people's emotions based on an egocentric bias, according to a new study by Associate Professor Hajimu Hayashi, Kobe University Graduate School of Human Development and Environment. The findings were published on June 1, 2019 in the Journal of Experimental Child Psychology.
7h
Genetic variation linked to response to anxiety could inform personalised therapies
A new study in marmoset monkeys suggests that individual variation in genes alters our ability to regulate emotions, providing new insights that could help in the development of personalised therapies to tackle anxiety and depression.
7h
Perceived threats to family increases women's willingness to sacrifice during war
Researchers at the Universities of Turku and Helsinki found that women were more likely to volunteer for all-female paramilitary organizations if they had brothers or husbands who were currently serving in the military. This result suggests that bonding with larger and frequently imagined communities, such as the nation state or religious groups, can arise from psychology mechanisms designed by ev
7h
Researchers at IDIBELL-ICO describe a new resistance mechanism
Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) and the ProCure Program of the Catalan Institute of Oncology (ICO) published today at Cancer Research a study describing a new mechanism in cancer that turns cells into malignant cells and contradicts what had been published so far about drug resistance that prevent the formation of blood vessels (anti-angiogenics). The research
7h
Regenerating human retinal ganglion cells in the dish to inform glaucoma treatment
People have a limited ability to regenerate nerves after injury or illness. In glaucoma patients, degeneration of the optic nerve that connects the retina and the brain causes permanent blindness, and there is currently no effective treatment. Now, researchers at the University of Nebraska Medical Center, USA, can induce human retinal ganglion cells, which form the optic nerve, to regenerate nerve
7h
International team of comet and asteroid experts agrees on natural origin for Oumuamua
14 asteroid and comet experts, including two from the University of Hawaii, determine that Oumuamua, the first recorded interstellar visitor, has natural origins, despite previous speculation by some other astronomers that the object could be an alien spacecraft sent from a distant civilization to examine our star system.
7h
Scientists discover processes to lower methane emissions from animals
University of Otago scientists are part of an international research collaboration which has made an important discovery in the quest to lower global agricultural methane emissions.
7h
UCI, UC Merced: California forest die-off caused by depletion of deep-soil water
The inability of long-rooted trees to reach their subsurface water supply in the Sierra Nevada mountain range led to widespread forest die-offs following the drought of 2012-2015. A new study from UC Irvine and UC Merced scientists provides a better understanding of the climatic and biological mechanisms in play.
7h
Building trust in artificial intelligence
From telecommunications to road traffic, from healthcare to the workplace—digital technology is now an intrinsic part of almost every area of life. Yet how can we ensure that developments in this field, especially those that rely on artificial intelligence (AI), meet all our ethical, legal and technological concerns? In a project led by the Fraunhofer Institute for Intelligent Analysis and Informa
7h
Microsoft's next major Windows update will be less disruptive
The Windows 10 May update did bring a lot of feature improvements including a native variable refresh rate setting, a light theme, better control over updates and improved Windows Hello. But …
7h
1 change gets more power from wind farms
Pointing turbines slightly away from oncoming wind—called wake-steering—can reduce that interference and improve both the quantity and quality of power from wind farms, research finds. The change would probably lower operating costs, too. Solitary wind turbines produce the most power when pointing directly into the wind. But when tightly packed lines of turbines face the wind on wind farms, wakes
7h
Can cancer defense in bats lead to better chemo?
New research may explain why bats have a low incidence of cancer. The findings could eventually lead to treatments for people. "Our team investigated the unique anti-cancer mechanisms in bats and found that exposure to toxic drugs caused significantly less DNA damage in bat cells than human cells due to the presence of the important ABCB1 protein," says senior author Koji Itahana, an associate pr
7h
Different kinds of thinking make teams smarter
To create the best collaboration in a work group, organizations should strike the right balance of different cognitive styles among the participants, according to a new study. In the study, researchers found that participants had to have just the right mix of cognitive diversity to create the highest collective intelligence. The ideal mix follows "the Goldilocks principle: Not too little (diversi
7h
How to keep your dog safe on the Fourth of July
Dogs can have a hard time on the Fourth of July, but there are ways to ensure their safety. Our celebrations could put pets at an increased risk for anxiety or injuries, explains Stacy Eckman, a clinical associate professor for the College of Veterinary Medicine & Biomedical Sciences at Texas A&M University. "Most of the time, injuries to pets during the holiday are related to them getting out of
7h
Sorry, but 'Oumuamua the Asteroid Wasn't Sent by Aliens, Say Scientists, For Some Reason Dignifying This Yet Again
Sorry, SETI In 2017, an asteroid came barreling past the Earth. That alone isn't particularly noteworthy, but this object was unlike any other. Not only was it the first to hail from outside our solar system , but it also had a weird shape and spin, plus it accelerated in an unexpected way while passing the Sun. Astronomers dubbed the strange asteroid 'Oumuamua, and soon, speculation swirled that
7h
Stunning Cosmic Fireworks Display Captured by Hubble, Right on Time
Explosions in the Sky Roughly 7,500 light-years away from Earth is a double star system called Eta Carinae. In 1838, one of the system's two stars underwent a near-death experience astronomers dubbed the "Great Eruption," and for nearly two centuries, scientists have been watching the stunning aftermath of that event. On Monday, researchers from NASA and the ESA released new photos of Eta Carinae
7h
New Method for Tackling Stroke Restrains an Overactive Immune System
Shutting down an inflammatory molecule could potentially provide treatment days after onset — Read more on ScientificAmerican.com
7h
Holy crocodiles: The cultural status of saltwater crocodiles in East Timor
East Timor's origin is shrouded in myth. The Southeast Asian island is said to have formed from "Grandfather Crocodile." That is why many who live on East Timor revere the animal who they believe established the island. A doctoral candidate of the Faculty of Environment and Natural Resources at the University of Freiburg, Sebastian Brackhane, investigated the challenges the belief poses for wildli
7h
New Method for Tackling Stroke Restrains an Overactive Immune System
Shutting down an inflammatory molecule could potentially provide treatment days after onset — Read more on ScientificAmerican.com
7h
Andrew Yang: We need a human-centered capitalism
Andrew Yang's universal basic income proposal has gained a lot of attention, but it is just one part of his "human-center capitalism" philosophy. Human-centered capitalism calls for government to refocus on human wellbeing, not GDP growth, as the go-to metric of economic success. Yang is one of many thinkers looking to update capitalism for the 21 st century. Andrew Yang's presidential bid has be
7h
Midsommar Is a Fascinating Departure From the Brutality of Hereditary
Late in Midsommar , the bewildered American tourist Christian (played by Jack Reynor) finally blurts out the question he's been holding in for his entire trip to the strange Swedish enclave of Harga. "Excuse me," he asks a bearded townsperson. "What is going on ?" He doesn't get a straight answer in return—the man just claps in his face, sending Christian's poor soul into yet another wave of psyc
7h
How to Watch the Solar Eclipse in South America
You can follow Tuesday's total solar eclipse, even if you aren't south of the Equator.
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A game that really exercises the mind
Researchers link three people on a brain-to-brain network. Nick Carne reports.
7h
A 'tsunami' on a silicon chip
Scientists in Sydney and Singapore create a world first for light waves. Phil Dooley reports.
7h
Total solar eclipses reveal the dark and stormy side of the sun we never see
In astronomy, we have a common saying: "good luck, and clear skies." For an eclipse chaser like me, this is especially important. We have two minutes and no second chance—one small cloud can spoil everything.
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Holy crocodiles: The cultural status of saltwater crocodiles in East Timor
East Timor's origin is shrouded in myth. The Southeast Asian island is said to have formed from "Grandfather Crocodile." That is why many who live on East Timor revere the animal who they believe established the island. A doctoral candidate of the Faculty of Environment and Natural Resources at the University of Freiburg, Sebastian Brackhane, investigated the challenges the belief poses for wildli
7h
A counterintuitive case in which like charges attract
When it comes to electric charge, there is one overriding theme: opposites attract, and like charges repel. But in a new study, physicists have made the surprising discovery that two spherical like-charged metal nanoparticles with unequal charges can attract one another in a dilute electrolyte solution. The reason, in short, is that the more strongly charged nanoparticle polarizes the metal core o
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Measuring the laws of nature
A physical constant, which is of great importance for basic research, has now be re-measured, with much higher precision than ever before.
7h
Unmanned aerial vehicles
Unmanned aerial vehicles, or UAVs, are increasingly used for tasks that are too difficult or dangerous for people to complete. But better control and communication among groups of similarly tasked UAVs is still needed, experts say.
7h
SpaceX Recovered Its First Rocket Fairing. Let's Crunch the Numbers!
SpaceX recovered its first fairing last week after a Falcon Heavy launch. Here's how to estimate the challenge faced by *Ms. Tree*, the retrieval boat.
8h
Rambøll: Slut med betalt fri på Grundlovsdag, ved begravelser og lægebesøg
PLUS. Omkring 3.000 medarbejdere hos Rambøll i Danmark kan fremover ikke holde fri med løn, når de skal til begravelser og ordinære lægebesøg. Ingeniørforeningen følger sagen.
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Tweeting while watching TV diminishes enjoyment
Toggling between viewing entertainment and social media lessens a person's ability to escape reality and enjoy a show, according to a new University of Connecticut study.
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Rewilding: As farmland and villages are abandoned, forests, wolves and bears are returning to Europe
Rewilding is often thought of as a fantastical vision of the future. One day we might share the landscape with wolves and bears, but in the present day, it seems unlikely. For many people in Europe though, that's exactly what they've been doing for at least the past decade.
8h
What You Lose When You Gain a Spouse
In America today, it's easy to believe that marriage is a social good—that our lives and our communities are better when more people get and stay married. There have, of course, been massive changes to the institution over the past few generations, leading the occasional cultural critic to ask: Is marriage becoming obsolete? But few of these people seem genuinely interested in the answer . More o
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Rewilding: As farmland and villages are abandoned, forests, wolves and bears are returning to Europe
Rewilding is often thought of as a fantastical vision of the future. One day we might share the landscape with wolves and bears, but in the present day, it seems unlikely. For many people in Europe though, that's exactly what they've been doing for at least the past decade.
8h
Generation and sampling of quantum states of light in a silicon chip
Scientists from the University of Bristol and the Technical University of Denmark have found a promising new way to build the next generation of quantum simulators combining light and silicon micro-chips.
8h
Germany fines Facebook $2.3 million under hate speech law
German authorities say they have issued Facebook with a 2 million-euro ($2.3 million) fine under a law designed to combat hate speech.
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Indonesia to return 49 containers of waste to Europe, US
Dozens of shipping containers full of waste will be returned to France and other developed countries, Indonesia said Tuesday, as Southeast Asian nations increasingly reject serving as dumping grounds for international trash.
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NASA launches Orion crew capsule to test abort system
NASA conducted a full-stress launch abort test Tuesday for the Orion capsules designed to carry astronauts to the moon.
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Natural gas boom on 'collison course' with climate goals
A global boom in natural gas pipelines and terminals is putting the energy industry on a "collision course" with the Paris climate goals, according to a new analysis of investment in the world's new favourite fuel.
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Internet restored in Ethiopia 10 days after assassinations
Ethiopia has begun restoring internet access Tuesday, 10 days after it was cut following the assassinations of six top government officials.
8h
Two Wyoming coal mines close, send 700 workers home after bankruptcy filing
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The future of hydrogen: Researchers at Puu Waawaa ranch explore energy solutions – Tucked among the old-time paniolo ranches in North Kona is a cutting-edge ranch of a different kind.
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Shopping Centers Exploring Facial Recognition in Brave New World of Retail
submitted by /u/gone_his_own_way [link] [comments]
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The U.S. Should Go Back to the Moon—but Not on Its Own: Do not make the U.S.'s lunar return an international clash. Collaboration, not conflict, is the sustainable path forward to the moon.
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Social Robots Play Nicely with Others – Droid friends and assistants are penetrating deeper into our lives
submitted by /u/gone_his_own_way [link] [comments]
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'Football pitch' of Amazon forest lost every minute: An area of Amazon rainforest roughly the size of a football pitch is now being cleared every single minute, according to satellite data, which may impact the effectiveness of current and future reforestation efforts to mitigate climate change.
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8h
McDonald's Continues To Phase In Artificial Intelligence | WGN Radio
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8h
Endless AI-generated spam risks clogging up Google's search results – A 'tsunami' of cheap AI content could cause problems for search engines
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8h
Evidence found that suggests dwarf planet Ceres is wrinkling
A team of researchers affiliated with several institutions in Spain has found evidence that suggests the dwarf planet Ceres is experiencing wrinkling on its surface. In their paper published in the journal Nature Astronomy, the group explains their study of data from the Dawn spacecraft and what it revealed.
8h
Isolating intact bacteria from blood using a microfluidic monolith device
Emerging single-cell diagnostics rely on the potential to rapidly and efficiently isolate bacteria from complex biological matrices. In a recent study now published in Microsystems and Nanoengineering, Jung Y. Han and colleagues at the interdisciplinary Departments of Mechanical Engineering, Chemical Biomolecular Engineering and Bioengineering in the U.S. developed a device to isolate intact and v
8h
Libra, Iran and the potential end of cryptocurrencies as we know them
Facebook's new cryptocurrency, libra, is being heralded as the moment that cryptocurrencies and blockchain, the technology that supports them, become truly mainstream. A notable rise in the price of bitcoin and many other cryptocurrencies in the run up to the libra announcement on June 18, and since, suggests a market directly responding to this possibility and bolstered by it.
8h
Tracking down dark matter
Over time, scientists have developed different theories to explain exactly what the mysterious dark matter might be made of. Researchers at Johannes Gutenberg University Mainz (JGU) have now found a way of detecting axions with the help of the Cosmic Axion Spin Precession Experiment (CASPEr) program. The basic assumption is that dark matter can influence the spin of nuclei, hence providing researc
8h
Equations help predict the behavior of water in rivers
University of Cordoba researchers developed a mathematical model that allows for anticipating the failure of dikes that hold in overflowing river water.
8h
Brain imaging may help identify teens at risk of increasing alcohol use
Teenagers with large amounts of grey matter in the brain at age 14 are more likely to increase their alcohol use over the next five years, according to a whole brain imaging study reported today in eLife.
8h
Bionic catalysts to produce clean energy
A biohybrid material that combines reduced graphene oxide with bacterial cells offers an eco-friendly option to help store renewable energy.
8h
Study finds dramatic differences in tests assessing preschoolers' language skills
Researchers examined the impact of preterm birth on language outcomes in preschoolers born preterm and full-term, using both standardized assessment and language sample analysis. They also explored semantic skills and grammatical ability, and nonlinguistic developmental skills of nonverbal intelligence, attention, and hyperactivity. Results show that language difficulties at the discourse level ma
8h
Vanished classmates: The effects of immigration enforcement on school enrollment
Partnerships between Immigration and Customs Enforcement (ICE) and local police departments designed to enforce immigration laws reduced the number of Hispanic students in US public schools in adopting counties by 10 percent after two years.
8h
Antidepressants reduce deaths by more than a third in patients with diabetes
Antidepressants reduce deaths by more than a third in patients with diabetes and depression, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.
8h
Integrated, multi-'omic' studies of asthma could lead to precision treatment
Carefully designed, integrated multi-'omic' studies could accelerate the use of precision medicine for asthma patients, according to researchers from the Icahn School of Medicine at Mount Sinai.
8h
NVIDIA GeForce RTX 2060 Super And RTX 2070 Super Card First Look Round-Up: MSI, EVGA, Zotac
Earlier today, we presented you with our review of the GeForce RTX 2060 Super and GeForce RTX 2070 Super. You can think of both cards as a preemptive strike against the yet-to-be-released Radeon …
8h
Sunken pleasure boats reveal the hidden history of California and beyond
The first Emerald Bay vacation camp on Lake Tahoe sprang up on the southwestern shores of the picturesque bay in 1884, some 20 years after railroads had begun to snake over mountain passes, making it possible for city dwellers to escape the hubbub of city life and find peace, solace and recreation in nature. As a result, Lake Tahoe became a mecca for wilderness lovers. Boating, fishing and hiking
8h
It takes years to fully recover from big storms like Sandy
The 2012 hurricane widely known as Superstorm Sandy left at least an estimated 325,000 New Jersey homes damaged or destroyed. Nearly seven years later, many of the New Jersey residents who have not fully recovered have to fend for themselves.
8h
Red, white but rarely blue—the science of fireworks colors, explained
In the earliest days of the United States, John Adams wrote to his wife Abigail about the celebration of independence, "It ought to be solemnized with Pomp and Parade, with Shews, Games, Sports, Guns, Bells, Bonfires and Illuminations from one End of this Continent to the other from this Time forward forever more." "Bonfires and illuminations" refer directly to what we know as pyrotechnics and fir
8h
Researcher reveals hidden world through the eyes of butterflies
An award-winning scientist and professor of evolutionary biology, Adriana Briscoe studies the evolution of vision in butterflies and how they see color. Briscoe is currently working on her first book, which is a memoir about, what else? Butterflies. A descendant of Mexican immigrants who fled the Mexican Revolution at the turn of the century and settled in San Bernardino, California, Briscoe has c
8h
Researcher reveals hidden world through the eyes of butterflies
An award-winning scientist and professor of evolutionary biology, Adriana Briscoe studies the evolution of vision in butterflies and how they see color. Briscoe is currently working on her first book, which is a memoir about, what else? Butterflies. A descendant of Mexican immigrants who fled the Mexican Revolution at the turn of the century and settled in San Bernardino, California, Briscoe has c
8h
Male crickets losing ability to sing, despite reproductive advantage of singing
In the past several decades, a mutation has spread among male Pacific field crickets (Teleogryllus oceanicus) in Hawaii that leads to wing structures that are unable to produce the crickets' signature chirping. While the mutation has kept crickets safe from a parasitic fly that uses cricket song to find its hosts, it also means the crickets are unable to sing to attract females. The fly's larvae b
8h
Gut Bacteria, Pitching In
When a patient takes an oral dose of a drug, you can picture it as being a little like one of the those Japanese pachinko machines, where a ball drops into a maze of complicated bouncing paths on its way to the bottom. There are a lot of things that happen once a pill hits the gut, the broad features of which process are described by the acronym ADME (absorption, distribution, metabolism, and exc
8h
Nobel Laureate Recalls Zoo Inspiration
— Read more on ScientificAmerican.com
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Her Nobel Research Outshines Her Star Turn
— Read more on ScientificAmerican.com
8h
From the archive
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02045-1 How Nature reported the official end of the First World War, and a chemical analysis of onion flavour and pungency.
8h
When drought threatens crops: NASA's role in famine warnings
NASA's satellite imagery and model forecasts regularly help agricultural and aid agencies to monitor the performance of crops worldwide and prepare for food shortages.
8h
Male crickets losing ability to sing, despite reproductive advantage of singing
In the past several decades, a mutation has spread among male Pacific field crickets (Teleogryllus oceanicus) in Hawaii that leads to wing structures that are unable to produce the crickets' signature chirping. While the mutation has kept crickets safe from a parasitic fly that uses cricket song to find its hosts, it also means the crickets are unable to sing to attract females. The fly's larvae b
8h
Study finds growth of faculty diversity largely minimal in U.S. colleges, universities
Colleges and universities across the nation lack the diversity needed among faculty to deliver a well-rounded education, says a new study in the recently launched South Texas College of Law Houston Hispanic Journal of Law and Policy.
8h
Poverty impacts child protection system contact
A child's chance of entering the child protection system is intrinsically linked to the deprivation of the area in which they live, University of Otago research has highlighted.
8h
Bird feeding chick cigarette end captured in picture
A US photographer captures a black skimmer bird feeding its chick a cigarette filter in Florida.
8h
Synthesizing chemical-sensing cells from scratch
Baking a cake from scratch is a task deemed difficult for many. Constructing an artificial cell-like system from scratch, well that's another story.
8h
Staring at the Sun, as It Disappeared
Vintage eclipse photos show our fascination with celestial shadows.
8h
Microfluidic Modulation Spectroscopy is Enabling the Next Generation in Protein Characterization
Download this eBook to learn about Microfluidic Modulation Spectroscopy, how it works, how it compares to Fourier-transform infrared (FTIR) spectroscopy, and how it can be used to measure protein aggregation, quantitation, structure, stability, and similarity!
8h
Is Bitcoin the new gold standard or another fiat?
A statistical analysis of volatility in cryptocurrencies has been carried out using a news impact curve. The analysis provides empirical evidence that could help economists decide whether these modern digital currencies are trust-based but intrinsically worthless like the "fiat" paper money system of familiar currencies we use or the new "gold standard." The research team offers details of their a
9h
Retire all existing and planned fossil fuel power plants to limit warming to 1.5°C
It will be very difficult to reduce greenhouse gas emissions by enough to halt global heating at 1.5°C—the threshold at which catastrophic climate change becomes more likely—according to a new paper published in Nature.
9h
An infrared close up of the moon
A first-of-its-kind camera developed in partnership between CU Boulder and Ball Aerospace will soon be landing on the moon.
9h
Physicist finds loose thread of string theory puzzle
A University of Colorado Boulder physicist is one step closer to solving a string theory puzzle 20 years in the making.
9h
Toxoplasma gondii utilizes at least two modes of locomotion during its infection cycle
Microbiologists at LMU have shown that Toxoplasma gondii, the parasite that is responsible for toxoplasmosis, utilizes at least two modes of locomotion during its infection cycle.
9h
Researchers detect bromine atoms in springtime Arctic
For the first time, researchers at the University of Michigan have detected bromine atoms in the atmosphere, and in doing so, have confirmed the reaction pathway through which mercury is removed from the atmosphere and enters the ecosystem in the springtime Arctic.
9h
Toxoplasma gondii utilizes at least two modes of locomotion during its infection cycle
Microbiologists at LMU have shown that Toxoplasma gondii, the parasite that is responsible for toxoplasmosis, utilizes at least two modes of locomotion during its infection cycle.
9h
Mechanical vibration generated by electron spins
Micro mechanical elements are indispensable components of modern electrical devices but the actuation of them requires electrical current. It becomes harder to wire the element as further downscaling of device is pursued. As a way out of this issue, researchers demonstrated a new way to deliver a force to drive micro mechanics by spin current.
9h
Synthesizing chemical-sensing cells from scratch
Scientists create artificial cells that can express distinct genes in response to specific chemical signals, opening the door to new ways of delivering drugs.
9h
What do sick kids really want in hospital?
Researchers at ECU's School of Nursing developed the 'Needs of Children Questionnaire' (NCQ), the first of its kind to measure children's self-reported psychosocial, physical and emotional needs in paediatric wards.
9h
Using facts to promote cancer prevention on social media is more effective than anecdotes
Clear information from trusted organizations has greater reach on social media than personal accounts.
9h
Copper compound shows further potential as therapy for slowing ALS
A compound with potential as a treatment for ALS has gained further promise in a new study that showed it improved the condition of mice whose motor neurons had been damaged by an environmental toxin known to cause features of ALS.
9h
A Special Class of Proteins Are Promising Targets for Drugs for Cancer and Alzehimer's
New possibilities for treating cancer and other ills — Read more on ScientificAmerican.com
9h
Technology can make collecting and analysing evidence for policy easier
There is more and more research being produced around the world every day. In total, about 3 million articles are published every year.
9h
Stellar stream of galaxy NGC 5907 has a morphology different than previously thought
Using Dragonfly Telephoto Array, astronomers have revisited the spiral galaxy NGC 5907 and provided more insights into the morphology of its stellar stream. The new observations indicate that this feature has a qualitatively different morphology than when it was observed about a decade ago. The new findings are reported in a paper published June 26 on arXiv.org.
9h
Whither the middle class?
A new OECD report, "Under Pressure: The Squeezed Middle Class," analyses how the middle class has fared in high-income countries between the 1980s and 2016. The results for the UK have some striking features.
9h
A look inside neural networks
Artificial intelligence (AI) is already firmly embedded in our everyday lives and is conquering more and more territory. For example, voice assistants are already an everyday item in many people's smartphones, cars and homes. Progress in the field of AI is based primarily on the use of neural networks. Mimicking the functionality of the human brain, neural networks link mathematically defined unit
9h
A species of cladoceran believed to be extinct has been rediscovered
In a lake in Finland, Senckenberg scientist Kay Van Damme rediscovered in collaboration with an international team a species of water flea that had long been considered extinct. While there are numerous fossil records of this cladoceran species, researchers were now able to document the first living specimens. Based on the small crustacean's morphology, the scientists were able to describe the ani
9h
Synthesizing chemical-sensing cells from scratch
Baking a cake from scratch is a task deemed difficult for many. Constructing an artificial cell-like system from scratch, well that's another story.
9h
Scientists discover processes to lower methane emissions from animals
University of Otago scientists are part of an international research collaboration which has made an important discovery in the quest to lower global agricultural methane emissions.
9h
Klimatet påverkas av hur vi använder markerna
Det är första gången som vegetation och markanvändning, och i synnerhet på den här detaljerade nivån, finns med i den klimatmodellering som görs inom EC-Earth, en global klimat- och jordsystemsmodell där forskare från Lunds universitet är delaktiga. – Nu kan vi göra riktade experiment för att förstå vilken betydelse markanvändning och dynamisk vegetation har för det globala klimatet, säger Paul M
9h
'Neon Genesis Evangelion' Is Remarkably Relevant in 2019
Two decades after its debut, a Netflix rerelease of the show is proving how prescient it is.
9h
I Opted Out of Facial Recognition at the Airport—It Wasn't Easy
Opinion: We've been assured that facial recognition technology is secure, reliable, and accurate. That's far from certain.
9h
When Earth and the Moon Were One
An entirely new class of astronomical object—a synestia—may be the key to solving the lingering mysteries of lunar origin — Read more on ScientificAmerican.com
9h
A Special Class of Proteins Are Promising Targets for Drugs for Cancer and Alzehimer's
New possibilities for treating cancer and other ills — Read more on ScientificAmerican.com
9h
A species of cladoceran believed to be extinct has been rediscovered
In a lake in Finland, Senckenberg scientist Kay Van Damme rediscovered in collaboration with an international team a species of water flea that had long been considered extinct. While there are numerous fossil records of this cladoceran species, researchers were now able to document the first living specimens. Based on the small crustacean's morphology, the scientists were able to describe the ani
9h
Climate change: Antarctic Peninsula 'can still avoid irreversible change'
A panel of Antarctic experts stresses the importance of keeping global temperature rise below 1.5C.
9h
Study provides a closeup view of zombifying bee parasite
Imagine becoming a zombie and digging your own grave. OK, don't imagine that.
9h
2019 Ford Ranger Midsize Pickup Review: What's New Again Is Old
The Ford Ranger is a solid pickup let down by an aging cockpit and no full-range adaptive cruise control. But there's nothing else this size with the 7,500-pound tow capacity. The post 2019 Ford Ranger Midsize Pickup Review: What's New Again Is Old appeared first on ExtremeTech .
9h
Kangaroo Island koalas may save the koala species
South Australia's Kangaroo Island koalas have been found to be free from the disease that is threatening koala populations around Australia, particularly in Australia's north-east where populations …
9h
Study provides a closeup view of zombifying bee parasite
Imagine becoming a zombie and digging your own grave. OK, don't imagine that.
9h
Decoding cells to unlock stem cells' potential
Stem cells are jacks of all trades, capable of alleviating the consequences of such diverse pathologies as heart attacks, strokes and cancer. However, stem cell therapies have been hampered by possible side effects, which are frequently hard to predict. One way around this conundrum is to understand how stem cells conjure up their therapeutic effects, and then try to mimic them.
9h
Altitude record for porcini mushrooms
ETH researchers have discovered Boletus edulis (porcini mushrooms) growing at an elevation of over 2,400 metres in the Lower Engadine—the highest altitude ever recorded for these popular edible mushrooms in the Alps. Moreover, the mushrooms have "hooked up" with a new plant partner that was not on their list of possible symbionts to date.
9h
Mechanical vibration generated by electron spins
Micro mechanical elements are indispensable components of modern electrical devices, but the actuation of them requires electrical current. It becomes harder to wire the element as further downscaling of device is pursued. As a way out of this issue, researchers demonstrated a new way to deliver a force to drive micro mechanics by spin current.
9h
Kangaroo Island koalas may save the koala species
South Australia's Kangaroo Island koalas have been found to be free from the disease that is threatening koala populations around Australia, particularly in Australia's north-east where populations are declining dramatically.
9h
Scientists weigh the balance of matter in galaxy clusters
A method of weighing the quantities of matter in galaxy clusters—the largest objects in our universe—has shown a balance between the amounts of hot gas, stars and other materials.
9h
Longer summer dry season observed in Congo rainforest
A recently documented long-term drying trend over the Congo Basin could have important implications on the future of the world's second largest rainforest, according to a study published today in Nature Climate Change.
9h
Landing the Mars 2020 rover: Autopilot will avoid terrain hazards autonomously
The view of the Sea of Tranquility rising up to meet Neil Armstrong during the first astronaut landing on the Moon was not what Apollo 11 mission planners had intended. They had hoped to send the lunar module Eagle toward a relatively flat landing zone with few craters, rocks and boulders. Instead, peering through his small, triangular commander's window, Armstrong saw a boulder field—very unfrien
9h
New camera system to offer high-resolution images and video of lunar landings
A new spacecraft-mounted camera system funded by NASA is poised to return the first high-resolution video of a landing plume as it lands on the moon.
9h
Climate change: Heatwave made 'at least' five times more likely by warming
The record heat experienced across Europe last week was made much more likely by rising temperatures say researchers.
9h
Decoding cells to unlock stem cells' potential
Stem cells are jacks of all trades, capable of alleviating the consequences of such diverse pathologies as heart attacks, strokes and cancer. However, stem cell therapies have been hampered by possible side effects, which are frequently hard to predict. One way around this conundrum is to understand how stem cells conjure up their therapeutic effects, and then try to mimic them.
9h
Altitude record for porcini mushrooms
ETH researchers have discovered Boletus edulis (porcini mushrooms) growing at an elevation of over 2,400 metres in the Lower Engadine—the highest altitude ever recorded for these popular edible mushrooms in the Alps. Moreover, the mushrooms have "hooked up" with a new plant partner that was not on their list of possible symbionts to date.
9h
Kangaroo Island koalas may save the koala species
South Australia's Kangaroo Island koalas have been found to be free from the disease that is threatening koala populations around Australia, particularly in Australia's north-east where populations are declining dramatically.
9h
Chemiluminescence probes for the rapid and sensitive detection of salmonella and listeria
Salmonella and listeria are among the most widely distributed and deadliest causes of foodborne infections. Their rapid and reliable detection on food and industrial food processing equipment is very important. In the journal Angewandte Chemie, scientists have introduced a new, ultrasensitive, chemiluminescence-based method for the direct detection of salmonella and listeria monocytogenes. Because
9h
Kirigami can spin terahertz rays in real time to peer into biological tissue
With a light-spinning device inspired by the Japanese art of paper cutting, University of Michigan researchers have detected microscopic twists in the internal structure of plant and animal tissue without harmful X-rays.
9h
Multi-year drought caused massive forest die-off in Sierra Nevada
The most extreme drought event in hundreds of years caused a catastrophic die-off of the Sierra Nevada's mature trees in 2015-2016.
9h
Tiny Lenses Will Enable Design of Miniature Optical Devices
Thin, flat metalenses could replace bulky glass for manipulating light — Read more on ScientificAmerican.com
9h
Complementary vibrational spectroscopic techniques used to test ancient burned bones
A team of researchers affiliated with several institutions in Italy has found a way to use three complementary vibrational spectroscopic techniques to test ancient burned bones. In their paper published in the journal Science Advances, the group describes the techniques they used and what they observed.
9h
Nuvarande löften om kolkraftsavveckling uddlösa mot klimatkrisen
Powering Past Coal Alliance , eller PPCA, är en sammanslutning av 30 länder och 22 städer och stater, som syftar till att avveckla kolkraft. Men medlemmar lovar främst att stänga äldre kraftverk som ändå är nära slutet av sin livslängd, vilket bara ger små utsläppsminskningar. Att utöka alliansen med de länder som använder mest kol skulle dessutom möta ekonomiska och politiska svårigheter. Genom
9h
Tiny Lenses Will Enable Design of Miniature Optical Devices
Thin, flat metalenses could replace bulky glass for manipulating light — Read more on ScientificAmerican.com
9h
That black hole photo: How event horizons bend time, space, and light
Black holes are usually surrounded by disks of very, very bright, very hot material. And that's how we find them. Black holes themselves give off no radiation at all. Any light gets absorbed into the black hole — all forms of light, from gamma rays to radio waves. A black hole's gravity is so strong it actually bends space itself. What does this mean? There's no way to get out of the black hole —
9h
Climate change made European heatwave at least five times likelier
Searing heat shows crisis is 'here and now', say scientists, and worse than predicted The record-breaking heatwave that struck France and other European nations in June was made at least five – and possibly 100 – times more likely by climate change, scientists have calculated . Such heatwaves are also about 4C hotter than a century ago, the researchers say. Furthermore, the heatwaves hitting Euro
9h
Investigative report on FDA enforcement under Trump from Science's news department
Despite being one of the nation's most vital watchdogs, compliance and enforcement actions by the US Food and Drug Administration (FDA) have severely declined since the Trump administration took office, according to an investigative report from Charles Piller, a contributing correspondent in the News department at Science.
9h
Climate change made Europe's heatwave at least five times more likely
Climate change attribution researchers have shown that record-breaking heat in France was made at least five times more likely by global warming
9h
Image of the Day: Side Salad
Bonobos eat their aquatic greens, perhaps to get their daily dose of iodine.
9h
Report: Louisiana among states vulnerable to losing jobs to robots – Louisiana, Texas and North Carolina are among the states where residents are most likely to lose their jobs to robots by 2030, according to a new report.
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9h
Russian space agency to use artificial intelligence in Moon's exploration – Science & Space – According to Roscosmos, the robotized systems will be used to reduce "possible risks for the health of humans and the cost of the program as a whole"
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Futuristic sounds to make electric buses safer hit wrong note – Fears 'spaceshippy' proposals by TfL to make vehicles audible could confuse pedestrians
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Chinese doctors conduct 5G-assisted remote surgeries – Doctors in a Beijing hospital conducted orthopedic surgeries for two patients in separate hospitals from two provinces using 5G wireless technology, hospital sources said.
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9h
NASA has completed a key test in preparing for its planned crewed space mission to return to the Moon, successfully testing the Launch Abort System (LAS for short) for its Orion spacecraft.
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Virtual reality is helping scientists discover new drugs – Chemists are using the virtual reality technology behind popular game Fortnite to visualize the structure of complex molecules. The tool, called 4Sight, has already been used to create a drug that is now in development to treat addiction.
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Sharing the land between nature and people: "The management of Earth's limited land is in the hands of nearly 8 billion people with different needs, wants, abilities, perspectives, and social relations. A better future…will depend on bringing all these hands together to shape it".
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9h
Cannabis could be an effective treatment option for pain and insomnia, for those looking to avoid prescription medications, including opioids, suggests a new study (n=1,000) of legalized marijuana. Among 65% of people taking cannabis for pain, 88% were able to stop taking opioid painkillers.
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9h
A wearable "Superpower Glass" device driven by artificial intelligence improved socialization in children with autism.
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9h
Norwegian ferry company Norled and its compatriot shipyard Westcon to Build World's 1st Hydrogen Ferry. "Our ambition is that the upcoming hydrogen ferry will become a new icon that will put Norway on the map to an even greater extent in maritime zero emission tech"
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9h
Social Robots Play Nicely with Others
Droid friends and assistants are penetrating deeper into our lives — Read more on ScientificAmerican.com
9h
The Meaning Behind the #UnwantedIvanka Meme
Bizarre Photoshops of the first family are typically more internet game than political commentary. This one's different.
10h
Making Mini-Brains from Stem Cells
A new report details the progress scientists have made in developing brain organoids from stem cells. They use human embryonic stem cells to culture neurons – brain cells. Lead author, Hideya Sakaguchi, describes the process : "The team cultured the organoids for 70-100 days, dissociated them into single cells and then disseminated them into another culture dish. The disseminated cells created ne
10h
Image of the Day: Side Salad
Bonobos eat their aquatic greens, perhaps to get their daily dose of iodine.
10h
Exclusive: FDA enforcement actions plummet under Trump
FDA actions that safeguard clinical trials, food and drug safety in steep decline, Science investigation reveals
10h
Nature is proud to support Pride in STEM
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02022-8 This year's International Day of LGBTQ+ People in Science, Technology, Engineering and Maths has our fullest backing.
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Does psychology have a conflict-of-interest problem?
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02041-5 Some star psychologists don't disclose in research papers the large sums they earn for talking about their work. Is that a concern?
10h
Apollo's Bounty: The Science of the Moon Rocks
The lunar rocks brought home by Apollo astronauts reshaped our understanding of the moon and the entire solar system. Gathering more of them is one of the most important reasons to go back — Read more on ScientificAmerican.com
10h
Social Robots Play Nicely with Others
Droid friends and assistants are penetrating deeper into our lives — Read more on ScientificAmerican.com
10h
The future isn't so golden for California's next wave of retirees
The dream of enjoying one's so-called Golden Years, or advanced years of life, in comfortable retirement may be a fantasy for an increasing number of working Californians.
10h
Getting more heat out of sunlight
A newly developed material that is so perfectly transparent you can barely see it could unlock many new uses for solar heat. It generates much higher temperatures than conventional solar collectors do—enough to be used for home heating or for industrial processes that require heat of more than 200 degrees Celsius (392 degrees Fahrenheit).
10h
Learning how to protect astronauts from space radiation
There is little known about the effects of space radiation on the human body. Astronauts cannot see or feel it, yet the high doses they are exposed to outside Earth's cocoon pose health hazards for trips to the Moon and Mars. To help investigate and find out more, European scientists can now accelerate atoms at close to the speed of light to learn how to protect astronauts.
10h
A Linguist's Case Against Socialism
Last month, Senator Bernie Sanders defined his vision for democratic socialism in an address at George Washington University. The speech elicited mixed reactions from political reporters and scholars, several of whom questioned how Sanders had evoked socialism , and from some of Sanders's Democratic rivals. When my colleague Edward-Isaac Dovere told Senator Michael Bennet the title of the speech,
10h
The Real Turning Point for Women's Political Power
O n February 13, 1920, Carrie Chapman Catt stood triumphant before the opening session of the National Woman Suffrage Association convention and declared the organization's decades-long mission finally accomplished. "Women be glad today. Let your voices ring out the gladness in your hearts," the 61-year-old suffragist said . Thirty-one states had so far ratified the Nineteenth Amendment, which ga
10h
Hungary passes controversial science sector reform bill
The Hungarian parliament passed a bill Tuesday enabling the takeover of research institutes by Prime Minister Viktor Orban's government, which is accused by critics of seeking to control key institutions and sectors.
10h
Internet på ferien: Pas på, når du logger på gratis wi-fi
Gratis net kan være en hacker-fælde, der vil stjæle dine personlige oplysninger.
10h
Why City Rankings Matter
Benchmarking is not just for headlines; it shapes cities' global imagination — Read more on ScientificAmerican.com
11h
Time is running out for sand
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02042-4 Sand and gravel are being extracted faster than they can be replaced. Monitor and manage this resource globally, urge Mette Bendixen and colleagues.
11h
Genmodifierade fiskar bidrar till kamp mot prostatacancer
– Resultaten kan komma till nytta för att hitta markörer som visar vilka cancerceller som är särskilt farliga för män med prostatacancer och därmed skulle vi kunna rikta behandlingen mer precist i framtiden, säger Maréne Landström, professor i patologi vid Umeå universitet. Prostatacancer är den vanligaste cancerformen bland män och skördar årligen cirka 2500 liv bara i Sverige. Så länge cancern
11h
Why City Rankings Matter
Benchmarking is not just for headlines; it shapes cities' global imagination — Read more on ScientificAmerican.com
11h
The U.S. Should Go Back to the Moon–But Not on Its Own
Do not make the U.S.'s lunar return an international clash — Read more on ScientificAmerican.com
11h
Yellow fever virus responsible for current epidemic in Brazil originated in Amazon in 1980
The origin of the virus responsible for the ongoing yellow fever epidemic in Brazil, the worst in 40 years, has been identified by scientists affiliated with two Brazilian institutions, Adolfo Lutz Institute (IAL) and the University of São Paulo (USP).
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Yellow fever virus responsible for current epidemic in Brazil originated in Amazon in 1980
The origin of the virus responsible for the ongoing yellow fever epidemic in Brazil, the worst in 40 years, has been identified by scientists affiliated with two Brazilian institutions, Adolfo Lutz Institute (IAL) and the University of São Paulo (USP).
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Chemists give chance a helping hand
Whether they are synthetic materials such as PET and Teflon, medicines or flavourings, life without synthetically produced compounds is barely conceivable. The chemical industry depends on efficient, long-term methods of producing synthetically derived molecules. For this purpose, chemists often use catalysts, i.e., additives with which they can facilitate and control chemical reactions. But how a
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Stop for nye biler og kraftværker: Kloden vil stadig få hedetur
Hvis hele verden straks holdt op med at bygge nye kraftværker og biler, ville menneskeheden stadig udlede så meget CO2, at temperaturen stiger mere end Paris-aftalens mål.
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The Space Station May Soon Smell like Fresh-Baked Cookies
Astronauts plan to test an oven designed to work in microgravity—and boost morale — Read more on ScientificAmerican.com
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Datacenter brød sammen: »Vandet fossede populært sagt ud af køleanlægget«
Søndag førte en stor lækage i køleanlægget i Interxions Ballerup-datacenter til, at flere it-systemer i landet gik i sort. Der er stadig oprydningsarbejde, der venter forude, lyder det fra datacentervirksomhedens managing director, Peder Bank.
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Korrekte telebeviser fra politiet kan være uigenkaldeligt slettet
Det er tvivlsomt, om Rigspolitiet kan genskabe teleoplysninger, der er mere end to år gamle.
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Fireworks Send Thousands of Americans to the ER Around the Fourth of July
Folks, please be careful with explosives on July 4.
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Nature Could Have Created Oddball 'Oumuamua, Not Aliens
The debate about 'Oumuamua's nature and origin continues.
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The Barrage of Bad News About Climate Change Is Triggering 'Eco-Anxiety,' Psychologists Say
We're all Amabella.
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One-of-a-Kind Copy of Galileo's Book That Upended the Heliocentric View of the Universe Was a Fraud.
They thought it was too good to be true … and it was.
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Food Sharing Apps Won't Solve Our Massive Food Waste Problem
Most food-waste-related apps focus on food recovery — that is, salvaging food that would have otherwise been thrown away and distributing it to others. While such apps do bridge local gaps between abundance and need, they don't address one of the main causes of food waste — societal norms.
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The Space Station May Soon Smell like Fresh-Baked Cookies
Astronauts plan to test an oven designed to work in microgravity—and boost morale — Read more on ScientificAmerican.com
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The weirdest stars we've ever seen have astronomers utterly baffled
The light from a pair of stars about 360 light years away dimmed and brightened again 28 times in three months and astronomers have no explanation
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Teaching AIs to make mistakes like kids would help them learn faster
AIs don't think like children, but if they made a common assumption that children use whilst learning a language they would become better faster
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Forecasters Caution 5G Will Interfere With Gathering Weather Data
Forecasters are nervous that 5G communications could interfere with collecting weather information. 5G happens to use bandwidths that include the frequency emitted by moisture in the air.
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Online Manipulation. Ultimately, the challenges regarding disinformation operations and platform governance will only grow more complex in the years to come.
submitted by /u/Wagamaga [link] [comments]
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Teaching AIs to make mistakes like kids would make them learn faster
AIs don't think like children, but if they made a common assumption that children use whilst learning a language they would become better faster
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How Long Can John Bolton Take This?
This weekend, at the invitation of Kim Jong Un, President Donald Trump stepped briefly across the demilitarized zone into North Korean territory, becoming the first sitting United States president to do so. That's one short waddle for a U.S. president, one giant leap for a supreme leader of the Democratic People's Republic of Korea. Previous presidents had refused to even contemplate such a gestu
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The Day Denuclearization Died
His advisers will deny it, but when Donald Trump stepped into North Korea on Sunday, he effectively stepped away from his administration's stated goal of fully eliminating Kim Jong Un's nuclear weapons. There were many remarkable aspects of the U.S. president's surprise meeting with the North Korean leader at the border, but perhaps the most notable was the absence of the issue that brought Trump
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For Democrats, Health Care Is Easy, but Immigration Is Hard
Among the many things we've learned so far in the presidential campaign is this: The Democratic candidates are talking more honestly about health care than about immigration. To develop a coherent approach to immigration in an era of rising asylum claims , Democrats need to explain—among other things—whom they would and wouldn't let in. But Donald Trump has made that discussion extraordinarily di
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A Supernatural Spy Story Goes Dark in The Rook
Somewhere along the line during the making of The Rook, a decision seems to have been made regarding tone. The book the new Starz series is based on, a 2012 supernatural spy thriller by Daniel O'Malley, is characterized by its humor, and by its weirdness (errant plot points include a cannibalistic cube of human flesh, sentient mold, and a man who sweats tear gas), a kind of Lovecraftian Jason Bou
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The Alt-Right's Tactical Cruelty
Donald Trump's rise triggered a debate about the so-called alt-right, how best to define it, and its role in the American political theater. Broadly speaking, two poles dominate that debate, as most of the public focuses its fleeting attention elsewhere. One side defines the alt-right broadly enough that it encompasses large swaths of the Republican Party, the conservative movement, and Trump sup
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During a Solar Eclipse, What Are Plants Doing?
Research conducted during the Great American Eclipse of 2017 suggests the sun's midday disappearance shocks some plants.
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Darwinian bee-keeping: lessons from the wild
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02043-3 A timely treatise on the plight of the honeybee Apis mellifera grips Gene E. Robinson.
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Why India is striking back against predatory journals
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02023-7 Our foe is determined and adaptable, says Bhushan Patwardhan. A list of credible titles is the latest salvo in the fight against shoddy scholarship.
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Markets must back climate mitigation
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02029-1 Markets must back climate mitigation
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Pity the pinnipeds: industry noise getting louder at sea
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02053-1 Pity the pinnipeds: industry noise getting louder at sea
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Fisheries subsidies wreck ecosystems, don't bring them back
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02054-0 Fisheries subsidies wreck ecosystems, don't bring them back
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Win–wins for health and climate — new report
Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02030-8 Win–wins for health and climate — new report
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Bekymret fagforening: Lokoførere skal køre forsigtigt på Ringstedbanen
Den uafhængige sikkerhedsrådgiver advarede imod at åbne banen med manuel overvågning og 120 kilometer i timen. Men Trafikstyrelsen gav dispensation.
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Collection of space sounds released to mark 50 years since the moon landings – video
To mark the 50th anniversary of the moon landings, an interactive collection of the sounds of space and the history of space travel has been launched by global sound project Cities and Memory. The project, called Space is the Place , combines 80 recordings from Nasa and the European Space Agency for the first time with reimagined, remixed interpretations of those space sounds, all designed to ans
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The Fall of Niels Birbaumer
A highly acclaimed neuroscientist whose work offered hope for many patients with brain injury has fallen from grace. Niels Birbaumer. From https://www.wysscenter.ch/person/niels-birbaumer-phd/ Prof. Niels Birbaumer, of the Eberhard-Karls University of Tübingen in Germany, came under investigation earlier this year. The probe began after researcher Martin Spüler raised serious concerns over a 2017
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Cardiac genetic mutation may not always predict heart disease
One in 10 people with this condition were born with a mutation in the TTN gene, but — until now — it has been unclear whether everyone with these mutations will inevitably develop dilated cardiomyopathy. In a new study, researchers at Penn Medicine and Geisinger reviewed gene sequences of more than 70,000 people, and found that 95 percent of patients who had the genetic mutations did not have he
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Why are we able to see moving objects against moving backgrounds?
If you want your friend to see you in a crowd, you wave your arms to stand out. As University of Rochester researchers found, one reason why this works is that the brain suppresses the background, allowing the person to focus on the moving object in front of them. As we age, our brains become less adept at suppressing background and reacting to foreground movement. But people can train their brain
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Molecular tuning of farnesoid X receptor partial agonism
Nature Communications, Published online: 02 July 2019; doi:10.1038/s41467-019-10853-2 The ligand-activated transcription factor farnesoid X receptor (FXR) acts as a cellular sensor for bile acids and is of interest as a drug target. Here the authors employ X-ray crystallography and NMR to characterize the molecular determinants of FXR agonists, antagonists and a partial agonist that drive FXR act
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Detection of anti-correlation of hot and cold baryons in galaxy clusters
Nature Communications, Published online: 02 July 2019; doi:10.1038/s41467-019-10471-y Galaxy clusters contain vast amount of dark matter and baryonic matter. Here the authors show the observational detection of the anti-correlation of gas mass and stellar mass observables in the most massive galaxy clusters, indicating such clusters retain close to the cosmic mix of baryons and dark matter.
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Fas signaling-mediated TH9 cell differentiation favors bowel inflammation and antitumor functions
Nature Communications, Published online: 02 July 2019; doi:10.1038/s41467-019-10889-4 Fas signalling induces apoptosis of activated T cells to maintain immune homeostasis. Here the authors show that Fas also induces PKC-β activation to promote NF-κB-mediated TH9 cell differentiation, while p38 activation by PKC-β antagonizes this effect, thereby supporting a synergy between p38 inhibitor and Fas
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Untwisted restacking of two-dimensional metal-organic framework nanosheets for highly selective isomer separations
Nature Communications, Published online: 02 July 2019; doi:10.1038/s41467-019-10971-x Metal-organic framework nanosheets are promising for separations, but interactions among them, affecting the performance, are largely unexplored. The authors reveal the favored stacking modes in a model system, and that untwisted restacking by thermal treatment improves isomer separation performance in gas chrom
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Chemical logic of MraY inhibition by antibacterial nucleoside natural products
Nature Communications, Published online: 02 July 2019; doi:10.1038/s41467-019-10957-9 Phospho-MurNAc-pentapeptide translocase (MraY) is a bacterial integral membrane enzyme that is essential for peptidoglycan biosynthesis. Here the authors present the crystal structures of MraY from Aquifex aeolicus bound to caprazamycin, capuramycin and mureidomycin and discuss the implications for antibiotic de
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Lysine/RNA-interactions drive and regulate biomolecular condensation
Nature Communications, Published online: 02 July 2019; doi:10.1038/s41467-019-10792-y Processing bodies (P-bodies) are non-membrane-bound protein/RNA granules in the cytosol. Here the authors combine bioinformatics, NMR and cell based assays and find that lysine is enriched in the disordered regions of P-body-associated proteins and show that lysine-rich polypeptides form highly dynamic lysine/RN
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Author Correction: Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model
Nature Communications, Published online: 02 July 2019; doi:10.1038/s41467-019-10950-2 Author Correction: Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model
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Spatial suppression promotes rapid figure-ground segmentation of moving objects
Nature Communications, Published online: 02 July 2019; doi:10.1038/s41467-019-10653-8 The visual system excels at segregating moving objects from their backgrounds, a key visual function hypothesized to be driven by suppressive centre-surround mechanisms. Here, the authors show that spatial suppression of background motion signals is critical for rapid segmentation of moving objects.
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New Ca. Liberibacter psyllaurous haplotype resurrected from a 49-year-old specimen of Solanum umbelliferum: a native host of the psyllid vector
Scientific Reports, Published online: 02 July 2019; doi:10.1038/s41598-019-45975-6 New Ca . Liberibacter psyllaurous haplotype resurrected from a 49-year-old specimen of Solanum umbelliferum : a native host of the psyllid vector
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Collapse on the line – how synthetic dimensions influence nonlinear effects
Scientific Reports, Published online: 02 July 2019; doi:10.1038/s41598-019-46060-8 Collapse on the line – how synthetic dimensions influence nonlinear effects
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Aqueous copper bioavailability linked to shipwreck-contaminated reef sediments
Scientific Reports, Published online: 02 July 2019; doi:10.1038/s41598-019-45911-8 Aqueous copper bioavailability linked to shipwreck-contaminated reef sediments
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Epidemiological, Clinical and Genetic Study of Hypophosphatasia in A Spanish Population: Identification of Two Novel Mutations in The Alpl Gene
Scientific Reports, Published online: 02 July 2019; doi:10.1038/s41598-019-46004-2 Epidemiological, Clinical and Genetic Study of Hypophosphatasia in A Spanish Population: Identification of Two Novel Mutations in The Alpl Gene
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Quaternized cellulose and graphene oxide crosslinked polyphenylene oxide based anion exchange membrane
Scientific Reports, Published online: 02 July 2019; doi:10.1038/s41598-019-45947-w Quaternized cellulose and graphene oxide crosslinked polyphenylene oxide based anion exchange membrane
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Nasal delivery of donepezil HCl-loaded hydrogels for the treatment of Alzheimer's disease
Scientific Reports, Published online: 02 July 2019; doi:10.1038/s41598-019-46032-y Nasal delivery of donepezil HCl-loaded hydrogels for the treatment of Alzheimer's disease
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Impact of weight variability on mortality among Korean men and women: a population based study
Scientific Reports, Published online: 02 July 2019; doi:10.1038/s41598-019-46037-7 Impact of weight variability on mortality among Korean men and women: a population based study
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Electrically driven spin torque and dynamical Dzyaloshinskii-Moriya interaction in magnetic bilayer systems
Scientific Reports, Published online: 02 July 2019; doi:10.1038/s41598-019-46009-x Electrically driven spin torque and dynamical Dzyaloshinskii-Moriya interaction in magnetic bilayer systems
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