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nyheder2019juli03

Immune-boosting compound makes immunotherapy effective against pancreatic cancer

Researchers at Washington University School of Medicine in St. Louis and Rush University in Chicago have found a compound that promotes a vigorous immune assault on pancreatic cancer. The findings, in mice, suggest a way to improve immunotherapy for the deadly disease in patients.

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Discovery linking microbes to methane emissions could make agriculture more sustainable

Common dairy cows share the same core group of genetically inherited gut microbes, which influence factors such as how much methane the animals release during digestion and how efficiently they produce milk, according to a new study.

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Scientists see how a protein preserves vision in a unique group of diabetic patients

An analysis of samples obtained from a well-studied cohort of over 1,000 patients affected by type 1 diabetes (T1D) for 50 years or longer has identified a protein that protects against an eye condition called diabetic retinopathy (DR) — one of the most common consequences of diabetes — which impacts most diabetic patients after 20 years of living with the disease.

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Ancient DNA sheds light on the origins of the Biblical Philistines

An international team analyzed for the first time, genome-wide data from people who lived during the Bronze and Iron Age in the ancient city of Ashkelon, one of the core Philistine cities. The team found that a European derived ancestry was introduced in Ashkelon around the time of the Philistines' estimated arrival, suggesting that ancestors of the Philistines migrated across the Mediterranean. T

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Pain signaling in humans more rapid than previously known

Pain signals can travel as fast as touch signals, according to a new study from researchers at Linköping University in Sweden, Liverpool John Moores University in the UK, and the National Institutes of Health (NIH) in the US. The discovery of a rapid pain-signaling system challenges our current understanding of pain. The study is published in the scientific journal Science Advances.

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11% of destroyed moist tropical forests could be restored to boost climate, environment

Researchers identified more than 100 million hectares of lost lowland tropical rain forests — restoration hotspots — spread out across Central and South America, Africa and Southeast Asia that present the most compelling opportunities for restoration to overcome rising global temperatures, water pollution and shortages, and the extinction of plant and animal life.

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Molecular thumb drives: Researchers store digital images in metabolite molecules

In a step toward molecular storage systems that could hold vast amounts of data in tiny spaces, Brown University researchers have shown it's possible to store image files in solutions of common biological small molecules.

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Scent composition data reveal new insights into perfume success

Mathematical analysis of online perfume data shows how the unique scent combinations found in different perfumes contribute to product popularity and consumer ratings. Vaiva Vasiliauskaite and Tim Evans of Imperial College London, UK, present these findings in the open-access journal PLOS ONE on July 3, 2019.

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Researchers save images not with a microchip, but with metabolites

An anchor, an ibex and an Egyptian cat: all images that a research team from Brown University, led by Jacob Rosenstein, encoded and decoded from mixtures of small molecules called metabolites. They demonstrate the potential of this small-molecule information storage system in a new paper published July 3, 2019 in the open-access journal PLOS ONE.

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During first year of university, poor diet and weight gain greater in male students

In students' first year of university, poor diet is linked to unhealthy weight gain with males affected more than females. The research publishing July 3 in the open access journal PLOS ONE by Kayleigh Beaudry and colleagues at Brock University, Canada also suggests that sex-specific strategies and interventions could improve dietary habits during the move to university.

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Murder in the Paleolithic? Evidence of violence behind human skull remains

New analysis of the fossilized skull of an Upper Paleolithic man suggests that he died a violent death, according to a study published July 3, 2019 in the open-access journal PLOS ONE by an international team from Greece, Romania and Germany led by the Eberhard Karls Universität Tübingen, Germany.

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CFTR inhibition: The key to treating bile acid diarrhea?

Estimates are that roughly 1% of people in Western countries may have bile acid diarrhea, including patients with Crohn's disease, ileal resection, diarrhea-predominant irritable bowel syndrome (IBS-D), and chronic functional diarrhea. Current management for bile acid diarrhea has demonstrated limited efficacy, with some therapies producing significant side effects. A recent study published in The

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Modern forensics solves Stone Age murder mystery after 33,000 years

A forensic analysis of a 33,000-year-old skull finds a clear explanation for the mysterious pattern of fractures preserved in the bone: it was murder

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We could store data inside the molecules that power our metabolism

The small molecules we use during metabolism form the basis of a new way to store digital information – and it could be more stable than electronic memory

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Ancient DNA reveals that Jews' biblical rivals were from Greece

Genetic sequencing of bones and teeth from ten Philistines who lived in what is now Israel 3200 years ago suggests a surge of migration from the Aegean at the time

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We could breed climate-friendly cows that belch less methane

Livestock are responsible for 14.5 per cent of global greenhouse gas emissions but it turns out that we could breed cows with gut bacteria that produce less methane

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Mechanism of scorpion toxin inhibition of K+ channel elucidated using high-speed AFM

Agitoxin-2 (AgTx2) from scorpion venom is a potent blocker of K+ channels. Researchers have now observed the binding dynamics of AgTx2 to the KcsA channel using high-speed atomic force microscopy. Single-molecule kinetic analyses revealed that the affinity of the channel for AgTx2 increased during persistent binding and decreased during persistent dissociation. The researchers propose a four-state

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Cold Case Closed: Scientists Pin 33,000-Year-Old Murder on a Left-Handed Paleo Killer

One of the coldest cases on record — a man's mysterious death about 33,000 years ago — has finally been solved: a left-handed murderer killed the man by smashing his skull with two consecutive blows, a new study finds.

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DNA Begins to Unlock Secrets of the Ancient Philistines

Genetic analysis of remains from ruins in Israel hints at the origins of the Levantine people described in the Hebrew Bible.

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Biblical Philistines—archenemies of ancient Israelites—hailed from Europe, DNA reveals

3000-year-old infant burials identify the much-maligned Philistines and shore up legends of Bronze Age migration

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Gut bacteria could be key to producing tastier cow’s milk

Research on cow microbiome could also reduce methane emissions from farm animals

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Berkeley Lights to Launch New T Cell Functional Analytics Platform at the 34th Congress of the International Society for Advancement of Cytometry (CYTO)

Berkeley Lights, Inc. (BLI), the leader in digital cell biology, today announced the launch of the LightningTM optofluidic platform, which directly visualizes phenotype and function of 1000s of T cells in days to help scientists address challenges in developing cancer immunotherapies.

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Murder in the Paleolithic? Evidence of violence behind human skull remains

New analysis of the fossilized skull of an Upper Paleolithic man suggests that he died a violent death, according to a study published July 3, 2019 in the open-access journal PLOS ONE by an international team from Greece, Romania and Germany led by the Eberhard Karls Universität Tübingen, Germany

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11% of destroyed moist tropical forests could be restored to boost climate, environment

In a peer-reviewed report released today, researchers have identified more than 100 million hectares of lost lowland tropical rain forests—restoration hotspots—spread out across Central and South America, Africa and Southeast Asia that present the most compelling opportunities for restoration to overcome rising global temperatures, water pollution and shortages, and the extinction of plant and ani

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Scent composition data reveal new insights into perfume success

Mathematical analysis of online perfume data shows how the unique scent combinations found in different perfumes contribute to product popularity and consumer ratings. Vaiva Vasiliauskaite and Tim Evans of Imperial College London, U.K., present these findings in the open-access journal PLOS ONE on July 3, 2019.

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Molecular thumb drives: Researchers store digital images in metabolite molecules

DNA molecules are well known as carriers of huge amounts of biological information, and there is growing interest in using DNA in engineered data storage devices that can hold vastly more data than our current hard drives. But new research shows that DNA isn't the only game in town when it comes to molecular data storage.

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Ancient DNA sheds light on the origins of the Biblical Philistines

An international team led by scientists from the Max Planck Institute for the Science of Human History and the Leon Levy Expedition have retrieved and analyzed genome-wide data from people who lived during the Bronze and Iron Ages (~3,600 to 2,800 years ago) in the ancient port city of Ashkelon, one of the core Philistine cities during the Iron Age. The team found that a European-derived ancestry

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Mechanism of scorpion toxin inhibition of K+ channel elucidated using high-speed AFM

Agitoxin-2 (AgTx2) from scorpion venom is a potent blocker of K+ channels. Researchers have now observed the binding dynamics of AgTx2 to the KcsA channel using high-speed atomic force microscopy. Single-molecule kinetic analyses revealed that the affinity of the channel for AgTx2 increased during persistent binding and decreased during persistent dissociation. The researchers propose a four-state

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Alcohol's second effects are more serious than we think, study says

A new study reveals that 21 percent of females and 23 percent of males have suffered the consequences of someone else's drinking. The secondhand effects of alcohol, including threats, vandalism, and financial problems, are underreported. Experts in the field recommend higher taxation to curb excessive drinking. None We certainly have strange definitions of freedom. Often the "freedom" one takes i

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Molecular thumb drives: Researchers store digital images in metabolite molecules

DNA molecules are well known as carriers of huge amounts of biological information, and there is growing interest in using DNA in engineered data storage devices that can hold vastly more data than our current hard drives. But new research shows that DNA isn't the only game in town when it comes to molecular data storage.

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A dynamic continental moisture gradient drove Amazonian bird diversification

The Amazon is the primary source of Neotropical diversity and a nexus for discussions on processes that drive biotic diversification. Biogeographers have focused on the roles of rivers and Pleistocene climate change in explaining high rates of speciation. We combine phylogeographic and niche-based paleodistributional projections for 23 upland terra firme forest bird lineages from across the Amazo

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Global restoration opportunities in tropical rainforest landscapes

Over 140 Mha of restoration commitments have been pledged across the global tropics, yet guidance is needed to identify those landscapes where implementation is likely to provide the greatest potential benefits and cost-effective outcomes. By overlaying seven recent, peer-reviewed spatial datasets as proxies for socioenvironmental benefits and feasibility of restoration, we identified restoration

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Hippocampal theta phases organize the reactivation of large-scale electrophysiological representations during goal-directed navigation

Humans are adept in simultaneously following multiple goals, but the neural mechanisms for maintaining specific goals and distinguishing them from other goals are incompletely understood. For short time scales, working memory studies suggest that multiple mental contents are maintained by theta-coupled reactivation, but evidence for similar mechanisms during complex behaviors such as goal-directe

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A heritable subset of the core rumen microbiome dictates dairy cow productivity and emissions

A 1000-cow study across four European countries was undertaken to understand to what extent ruminant microbiomes can be controlled by the host animal and to identify characteristics of the host rumen microbiome axis that determine productivity and methane emissions. A core rumen microbiome, phylogenetically linked and with a preserved hierarchical structure, was identified. A 39-member subset of

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An ultrafast system for signaling mechanical pain in human skin

The canonical view is that touch is signaled by fast-conducting, thickly myelinated afferents, whereas pain is signaled by slow-conducting, thinly myelinated ("fast" pain) or unmyelinated ("slow" pain) afferents. While other mammals have thickly myelinated afferents signaling pain (ultrafast nociceptors), these have not been demonstrated in humans. Here, we performed single-unit axonal recordings

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Relativistic electrons generated at Earths quasi-parallel bow shock

Plasma shocks are the primary means of accelerating electrons in planetary and astrophysical settings throughout the universe. Which category of shocks, quasi-perpendicular or quasi-parallel, accelerates electrons more efficiently is debated. Although quasi-perpendicular shocks are thought to be more efficient electron accelerators, relativistic electron energies recently observed at quasi-parall

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Exercise training improves motor skill learning via selective activation of mTOR

Physical exercise improves learning and memory, but little in vivo evidence has been provided to illustrate the molecular mechanisms. Here, we show that chronic treadmill exercise activates the mechanistic target of rapamycin (mTOR) pathway in mouse motor cortex. Both ex vivo and in vivo recordings suggest that mTOR activation leads to potentiated postsynaptic excitation and enhanced neuronal act

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Synchronous crop failures and climate-forced production variability

Large-scale modes of climate variability can force widespread crop yield anomalies and are therefore often presented as a risk to food security. We quantify how modes of climate variability contribute to crop production variance. We find that the El Niño Southern Oscillation (ENSO), the Indian Ocean Dipole (IOD), tropical Atlantic variability (TAV), and the North Atlantic Oscillation (NAO) togeth

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Voter information campaigns and political accountability: Cumulative findings from a preregistered meta-analysis of coordinated trials

Voters may be unable to hold politicians to account if they lack basic information about their representatives’ performance. Civil society groups and international donors therefore advocate using voter information campaigns to improve democratic accountability. Yet, are these campaigns effective? Limited replication, measurement heterogeneity, and publication biases may undermine the reliability

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Hepatocyte-specific HIF-1{alpha} ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation

The decrease in incretin effects is an important etiologic component of type 2 diabetes with unknown mechanisms. In an attempt to understand obesity-induced changes in liver oxygen homeostasis, we found that liver HIF-1α expression was increased mainly by soluble factors released from obese adipocytes, leading to decreased incretin effects. Deletion of hepatocyte HIF-1α protected obesity-induced

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Imaging CAR T cell therapy with PSMA-targeted positron emission tomography

Chimeric antigen receptor (CAR) T cell therapy for hematologic malignancies is fraught with several unknowns, including number of functional T cells that engage target tumor, durability and subsequent expansion and contraction of that engagement, and whether toxicity can be managed. Non-invasive, serial imaging of CAR T cell therapy using a reporter transgene can address those issues quantitative

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Ancient DNA sheds light on the genetic origins of early Iron Age Philistines

The ancient Mediterranean port city of Ashkelon, identified as "Philistine" during the Iron Age, underwent a marked cultural change between the Late Bronze and the early Iron Age. It has been long debated whether this change was driven by a substantial movement of people, possibly linked to a larger migration of the so-called "Sea Peoples." Here, we report genome-wide data of 10 Bronze and Iron A

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Single-base mapping of m6A by an antibody-independent method

N 6 -methyladenosine (m 6 A) is one of the most abundant messenger RNA modifications in eukaryotes involved in various pivotal processes of RNA metabolism. The most popular high-throughput m 6 A identification method depends on the anti-m 6 A antibody but suffers from poor reproducibility and limited resolution. Exact location information is of great value for understanding the dynamics, machiner

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High-speed AFM reveals accelerated binding of agitoxin-2 to a K+ channel by induced fit

Agitoxin-2 (AgTx2) from scorpion venom is a potent blocker of K + channels. The docking model has been elucidated, but it remains unclear whether binding dynamics are described by a two-state model (AgTx2-bound and AgTx2-unbound) or a more complicated mechanism, such as induced fit or conformational selection. Here, we observed the binding dynamics of AgTx2 to the KcsA channel using high-speed at

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Osteoblastic lysosome plays a central role in mineralization

Mineralization is the most fundamental process in vertebrates. It is predominantly mediated by osteoblasts, which secrete mineral precursors, most likely through matrix vesicles (MVs). These vesicular structures are calcium and phosphate rich and contain organic material such as acidic proteins. However, it remains largely unknown how intracellular MVs are transported and secreted. Here, we use s

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CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism

Using biochemical characterization of fusion proteins associated with endometrial stromal sarcoma, we identified JAZF1 as a new subunit of the NuA4 acetyltransferase complex and CXORF67 as a subunit of the Polycomb Repressive Complex 2 (PRC2). Since CXORF67’s interaction with PRC2 leads to decreased PRC2-dependent H3K27me2/3 deposition, we propose a new name for this gene: CATACOMB (catalytic ant

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Ancient DNA sheds some light on a Mediterranean mystery

Movement of people – not just ideas – brought Philistine culture to the ancient near east. Dyani Lewis reports.

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Using maths to mix the perfect perfume

Researchers use online data and network analysis to find the best blend of scents. Mark Bruer reports.

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Ancient DNA reveals the origins of the Philistines

A mysterious Biblical-era population may have fled Bronze Age calamities.

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A Physicist and His Son Are 3D-Printing a Full-Scale Lamborghini

Lambo 3D Fifteen years ago, the Motion Picture Association of America released an anti-piracy public service announcement — that has since turned into a meme — aimed at those who illegally downloaded media online. “You wouldn’t steal a car,” a message read during the opening credits of most commercial DVDs at the time. Now, 3D printing could make the silly message a reality. Physicist Sterling Ba

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AI Poised to Ruin Internet Using “Massive Tsunami” of Fake News

Spam City New tools can recreate a human’s face and or writer’s voice to frightening levels of accuracy. Among the most concerning of these is the deceivingly-adorably-named GROVER a fake news-writing bot that people have used the tool to make blogs and even entire subreddits illustrate the problems AI-written news can pose to the world. Do not let the adorable blue namesake puppet on the first p

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Timing of exercise may be key to successful weight loss

In a new study of 375 adults who have successfully maintained weight loss and who engage in moderate-to-vigorous intensity physical activity, most reported consistency in the time of day that they exercised, with early morning being the most common time.

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NASA changes how it divvies up telescope time to reduce gender bias

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02064-y The switch to double-blind peer review will affect roughly 650 scientists working on projects worth an estimated US$55 million.

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Known unknowns: How to communicate certainly in an uncertain world

From the speed of global warming to the likelihood of developing cancer, we must grasp uncertainty to understand the world. Here’s how to know your unknowns

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Every single neuron in an animal mapped out for the first time

A complete map of all the neurons and their connections in both sexes of an animal – a tiny worm – has been described for the first time

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Photos of the 2019 Total Solar Eclipse

Yesterday, thousands of people in Chile and Argentina stood outside and gazed at the sky as day turned briefly to night during this year’s only total solar eclipse. For two minutes, Earth’s moon completely blocked the sun, allowing observers in the path of its shadow to see solar prominences and the sun’s vast corona extending out into space. Gathered here, a few images of yesterday’s celestial e

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Acne’s Wonder Drug Is a Mental-Health Puzzle

In 2002, a family filed a lawsuit alleging that an acne drug made their teenage son suicidal. Accutane, a since-discontinued brand name for the drug isotretinoin, works wonders for cysts and pimples that don’t respond to other treatments. But since the FDA approved isotretinoin in 1982, it had been plagued by controversy over whether it could alter brain chemistry and cause depression. In the 200

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CRISPR Helps Scientists Cure HIV In Living Animals For First Time

One-Two Combo For the first time, researchers have eliminated HIV , the virus that causes AIDS, from the genomes of living animals — a major accomplishment along the path to freeing the world of this deadly disease. For the study , published Tuesday in the journal Nature Communications , researchers from Temple University and the University of Nebraska Medical Center started by engineering mice t

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Plants don't think, they grow: The case against plant consciousness

If a tree falls, and no one's there to hear it, does it feel pain and loneliness? No, experts argue in an opinion article publishing on July 3 in the journal Trends in Plant Science. They draw this conclusion from recent research which explores the evolution of consciousness through comparative studies of simple and complex animal brains.

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'Tsunami' on a silicon chip: A world first for light waves

Scientists have for the first time manipulated a light wave, or photonic information, on a silicon chip that retains its overall 'shape'. This foundational work is important because most communications infrastructure still relies on silicon-based devices for propagation and reception of information. Manipulating solitons on-chip could potentially allow for the speed up of photonic communications d

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Bacteria engineered as Trojan horse for cancer immunotherapy

Researchers have engineered a strain of non-pathogenic bacteria that can colonize solid tumors in mice and safely deliver potent immunotherapies, acting as a Trojan Horse that treats tumors from within. The therapy led not only to complete tumor regression in a mouse model of lymphoma, but also significant control of distant, uninjected tumor lesions.

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It's not an antibody, it's a frankenbody: A new tool for live-cell imaging

Researchers have added a new tool to the arsenal of antibody-based probes, but with a powerful distinction: Their genetically encoded probe works in living cells.

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More 'reactive' land surfaces cooled the Earth down

In a new study, researchers from ETH Zurich, Stanford University the GFZ German Research Centre for Geosciences show that a paradigm on a global temperature drop that started around 15 million years ago cannot be upheld. With the help of a computer model they explain the Earth's cooling with an increased 'reactivity' of the land surface that has led to a decrease in CO2 in the atmosphere, reducing

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Experiments show dramatic increase in solar cell output

Researchers at MIT and Princeton have found a way to increase the output of silicon solar cells by allowing a single photon to release two electrons in the silicon.

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Immune cells invade aging brains, disrupt new nerve cell formation, Stanford study finds

A study by Stanford University School of Medicine investigators has revealed that immune cells infiltrate the rare newborn nerve-cell nurseries of the aging brain. There's every reason to think those interlopers are up to no good. Experiments in a dish and in living animals indicate they're secreting a substance that chokes off new nerve cell production.

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Ovarian and breast cancer research finds new ways BRCA1 gene functions

Research has found important new ways that the BRCA1 gene functions which could help develop our understanding of the development of ovarian and breast cancers.

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With little training, machine-learning algorithms can uncover hidden scientific knowledge

Researchers at Lawrence Berkeley National Laboratory have shown that an algorithm with no training in materials science can scan the text of millions of papers and uncover new scientific knowledge. They collected 3.3 million abstracts of published materials science papers and fed them into an algorithm called Word2vec. By analyzing relationships between words the algorithm was able to predict disc

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First complete wiring diagram of an animal's nervous system

In a study published online today in Nature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism. The study includes adults of both sexes and reveals substantial differences between them.

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Amazon forced to admit it may keep hold of your data even AFTER you delete audio clips

US senator for Delaware, the democrat Chris Coons sent a letter to Amazon chief Jeff Bezos demanding answers to how the firm uses audio recordings of users.

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Quorn protein builds muscle better than milk protein

A study has found that mycoprotein, the protein-rich food source that is unique to Quorn products, stimulates post-exercise muscle building to a greater extent than milk protein.

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Ultra-small nanoprobes could be a leap forward in high-resolution human-machine interfaces

Machine enhanced humans — or cyborgs as they are known in science fiction — could be one step closer to becoming a reality, thanks to new research.

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How to sell labriculture: Less lab, more culture

In the near future, we will be able to mass-produce meat directly from animal cells. This cultured meat could change the world — or it could falter like GM 'frankenfoods.' Writing in Frontiers in Nutrition, researchers warn that the most common media framing of cultured meat — as a 'high-tech' innovation — may be the least effective in garnering consumer acceptance.

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Can mathematics help us understand the complexity of our microbiome?

In humans, the gut microbiome is an ecosystem of hundreds to thousands of microbial species living within the gastrointestinal tract, influencing health and even longevity. As interest in studying the microbiome continues to increase, understanding this complexity will give us predictive power to engineer it. A research team built a rigorous mathematical framework that describes the ecology of a m

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Are you sure it's burning mouth syndrome?

Not all burning mouths are the result of a medical condition known as 'burning mouth syndrome' (BMS) and physicians and researchers need better standards for an appropriate diagnosis, according to new research.

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It's dog eat dog on the canine social ladder

Climbing the social ladder is a 'ruff' business for dogs, new research shows.

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Astronomers help wage war on cancer

Techniques developed by astronomers could help in the fight against breast and skin cancer.

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Ultra-small nanoprobes could be a leap forward in high-resolution human-machine interfaces

Machine enhanced humans — or cyborgs as they are known in science fiction — could be one step closer to becoming a reality, thanks to new research.

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Worm Wiring Diagram May Help Us Understand Our Own Nervous System

Genes for the humble C. elegans turn up in autism, schizophrenia and other human disorders — Read more on ScientificAmerican.com

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These Kinetic, Wrinkle Free Pants Use Your Body’s Heat to Maintain a Perfectly Pressed Look

Even though research indicates that the clothes you wear can alter your performance, you don’t always have a say in the matter. Professional work environments oftentimes have rules in place that force us to dress a certain way, even if it’s uncomfortable. This is because studies indicate that dressing the part helps people perform better at work. But what about when you need to feel comfortable i

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Podcast: Machine learning in materials science, and sand’s sustainability

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02073-x Listen to the latest from the world of science, with Benjamin Thompson and Nick Howe.

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An exciting boost for solar cells

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02014-8 A process called singlet fission has the potential to enhance the efficiency of solar cells. The mechanism has been difficult to implement in such devices, but experiments demonstrate a way forward.

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Single-cell analysis reveals T cell infiltration in old neurogenic niches

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1362-5 Single-cell transcriptomic analysis of neurogenic niches in young and old mice reveals that T cells infiltrate the neurogenic niches of old mice and inhibit the proliferation of neural stem cells, in part through expression of interferon-γ.

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Insect egg size and shape evolve with ecology but not developmental rate

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1302-4 Analyses of insect eggs as well as genetic and life-history traits of insects show that where eggs are laid, rather than universal allometric constants, developmental rate or adult body size, underlies size and shape evolution.

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Sensitization of silicon by singlet exciton fission in tetracene

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1339-4 A silicon and tetracene solar cell employing singlet fission uses an eight-angstrom-thick hafnium oxynitride interlayer to promote efficient triplet transfer, increasing the efficiency of the cell.

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Magnetic monopole noise

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1358-1 Magnetic-flux noise measurements with a SQUID-based spectrometer demonstrate the presence of a magnetic monopole plasma in Dy2Ti2O7.

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The biologist using insect eggs to overturn evolutionary doctrine

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02040-6 Cassandra Extavour has transformed understanding of animal development — while championing diversity, and nurturing a side career as a soprano.

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New name for breast-cancer syndrome could help to save lives

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02015-7 People of all sexes can have risk genes that are often assumed to affect only women. Renaming the syndrome should aid cancer prevention and treatment, argues Colin C. Pritchard.

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Isomerization of BRCA1–BARD1 promotes replication fork protection

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1363-4 BRCA1–BARD1 has a role in replication fork protection that is mediated by a mechanism of phosphorylation-targeted isomerization of BRCA1 and is independent of the canonical interaction between BRCA1 and PALB2.

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Author Correction: Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1351-8 Author Correction: Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance

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Unsupervised word embeddings capture latent knowledge from materials science literature

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1335-8 Natural language processing algorithms applied to three million materials science abstracts uncover relationships between words, material compositions and properties, and predict potential new thermoelectric materials.

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Neural networks mapped in both sexes of the worm

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02006-8 Understanding how the brain’s functions emerge from the workings of neural circuits is a central pursuit of neuroscience. New wiring diagrams of the nervous system in both sexes of a worm mark important progress.

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Interacting Floquet polaritons

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1354-5 Frequency modulation is used to create ‘Floquet polaritons’—strongly interacting quasi-particles that exist in a customizable set of modes.

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How mutations express themselves in blood-cell production

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02028-2 A method for detecting mutations and measuring gene-expression levels in the same cell has enabled an investigation into the effects of mutations in a specific gene on the emergence of a form of blood cancer.

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Text mining facilitates materials discovery

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-01978-x Computer algorithms can be used to analyse text to find semantic relationships between words without human input. This method has now been adopted to identify unreported properties of materials in scientific papers.

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Neogene cooling driven by land surface reactivity rather than increased weathering fluxes

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1332-y A carbon cycle model constrained by weathering-sensitive isotopic tracers reveals that long-term cooling in the Neogene period reflects a change in how surface denudation is partitioned into weathering and erosion.

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Whole-animal connectomes of both Caenorhabditis elegans sexes

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1352-7 Quantitative connectivity matrices (or connectomes) for both adult sexes of the nematode Caenorhabditis elegans are presented that encompass all connections from sensory input to end-organ output across the entire animal.

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Hyperbolic lattices in circuit quantum electrodynamics

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1348-3 An interconnected network made of superconducting microwave resonators is created as a step towards quantum simulations of interacting particles in hyperbolic space.

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Infiltration of old brains by T cells causes dysfunction of neural stem cells

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-01832-0 Age-dependent changes in their environment can impair stem cells’ function. The finding that T cells infiltrate the brains of aged mice and cause dysfunction of neural stem cells reveals a potential therapeutic target.

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Somatic mutations and cell identity linked by Genotyping of Transcriptomes

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1367-0 Profiling of over 38,000 CD34+ cells from patients with CALR-mutated myeloproliferative neoplasms, using the ‘Genotyping of Transcriptomes’ procedure, reveals that the transcriptional output of these mutations depends upon native cell identity.

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The 2019 South American Eclipse, as Captured By Those on the Ground

The solar eclipse took place around 4:30 p.m. EDT over parts of South America. (Credit: Mike Newbry on Unsplash) A total solar eclipse blazed a path through parts of South America on July 2, 2019. Tens of thousands of tourists and locals looked skywards in Chile and Argentina to see the midday light turn to darkness as the sun and the moon crossed paths. Totality, the point at which the Moon cover

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With CRISPR and Medication, Scientists Remove HIV Virus from Mice

(Credit: Evgeniy Kalinovskiy/Shutterstock) Nearly 37 million people suffer from human immune deficiency virus or HIV, the virus that causes AIDS. The go-to treatment for the infection is antiretroviral therapy, better known as ART. It can prevent the progression of the disease, enabling infected individuals to live longer, healthier lives. But even with ART, the virus still lingers in the body. No

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More 'reactive' land surfaces cooled the Earth down

There have been long periods of cooling in Earth's history. Temperatures had already fallen for more than 10 million years before the last ice age began about 2.5 million years ago. At that time, the northern hemisphere was covered with massive ice masses and glaciers. A geoscientific paradigm, widespread for over 20 years, explains this cooling with the formation of the large mountain ranges such

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First complete wiring diagram of an animal's nervous system

In a study published online today in Nature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism. The study includes adults of both sexes and reveals substantial differences between them.

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Magnetic monopoles make acoustic debut

University College Cork (UCC) & University of Oxford Professor of Physics, Séamus Davis, has led a team of experimental physicists in the discovery of the magnetic noise generated by a fluid of magnetic monopoles.

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Geoff White obituary

In 1985 the work research unit of the Department of Employment was disbanded and my father, Geoff White, stepped down after five years as director. A colleague wrote: “It is not often that one person can make a national and international contribution to such a worthy cause; the quality of working life in the UK will always be linked with the name of Geoff White.” Geoff, who has died aged 93, was

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Worm Wiring Diagram May Help Us Understand Our Own Nervous System

Genes for the humble C. elegans turn up in autism, schizophrenia and other human disorders — Read more on ScientificAmerican.com

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Machine-learning algorithms can discover new things

Research shows they could even help us cut through the paperwork. Nick Carne reports.

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Rogue immune cells can infiltrate old brains

Killer T cells get into older brains where they may make mischief, a study in mice and postmortem human brain tissue finds.

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Why some insect eggs are spherical while others look like hot dogs

Analyzing a new database of insect eggs’ sizes and shapes suggests that where eggs are laid helps explain some of their diversity of forms.

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A mechanism that makes infants more likely than adults to die from sepsis is discovered

Scientists at the Center for Research on Inflammatory Diseases (CRID) show why pediatric patients with sepsis suffer from more inflammation and organ injury than adults. New treatment strategies may be tested.

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Ecology, Not Physics, Explains Diversity of Insect Eggs

Insect eggs can take any shape at almost any size, refuting explanations for their dimensions based on geometric scaling laws or on relationships between egg traits and adult traits.

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The wiring of worms revealed

Scientists present the first diagram of an animal’s nervous system. Paul Biegler reports.

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First complete wiring diagram of an animal's nervous system

In a study published online today in Nature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism. The study includes adults of both sexes and reveals substantial differences between them.

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Worm Wiring Diagram May Help Us Understand Our Own Nervous System

Genes for the humble C. elegans turn up in autism, schizophrenia and other human disorders — Read more on ScientificAmerican.com

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What a Pediatrician Saw Inside a Border Patrol Warehouse

MCALLEN, Texas—Inside the Border Patrol warehouse on Ursula Avenue, Dolly Lucio Sevier saw a baby who’d been fed from the same unwashed bottle for days; children showing signs of malnutrition and dehydration; and several kids who, in her medical opinion, were exhibiting clear evidence of psychological trauma. More than 1,000 migrant children sat in the detention facility here, and Sevier, a local

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Billionaires Are Dead Serious About Moving Factories to Space

Space Industries It sounds like science fiction, but the idea of moving heavy industries off Earth seems far less far-fetched ever before. Collecting resources from other planets or asteroids instead of using up what little we have left on Earth could be the key to ensuring that human beings survive, Discover Magazine reports . “The solar system can support a billion times greater industry than w

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USC Apologizes for Taking Over UCSD's Alzheimer's Program

The University of Southern California reaches a settlement with the University of California, San Diego, over snatching staff, data, and funding in 2015.

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11,898 Solar Eclipses in 5,000 Years

Precisely when and where eclipses occur is a complicated business — Read more on ScientificAmerican.com

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Samband mellan fetma och tarmbakterier

Fetma uppkommer när energiintaget i det vi äter är större än den energi vi förbrukar. Men förmågan att behålla energibalansen varierar mellan individer. I dag vet vi att orsaken beror på flera faktorer där ärftlighet (genetisk predispositon) och livsstil (kost och motion) är de mest kända. Bakterierna i tarmfloran tros spela en viktig roll i såväl utvecklingen av fetma som i utvecklingen av sjukd

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Possible Alien Radio Signals Way More Common Than Believed

Spam Calls Last week, astronomers managed to trace a mysterious, fleeting radio signal back to a distant galaxy. Since then, teams from around the world have tracked down ten more. The latest was spotted by a team at CalTech’s Owens Valley Radio Observatory on Tuesday, according to CNET . Astronomers aren’t positive what’s causing these so-called “Fast Radio Bursts” — there are several plausible

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Team discovers control of cell signaling using a cobalt (III)-nitrosyl complex

Two professors' joint research team has discovered how to synthesize new materials to deliver nitric oxide, which controls the cell activation signal. The cell signaling control is expected to contribute positively to the development of treatment for cardiovascular diseases.

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Lizzo's 'Juice' Is the Most Patriotic Song of 2019

It's not just any old anthem—drenched as it is in themes of self-love and optimism—but the anthem.

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Toxic algae increases in Florida's Lake Okeechobee

Recent tests results show that toxic amounts of blue-green algae have surfaced in Lake Okeechobee, according to data released by the Florida Department of Environmental Protection.

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Team discovers control of cell signaling using a cobalt (III)-nitrosyl complex

Two professors' joint research team has discovered how to synthesize new materials to deliver nitric oxide, which controls the cell activation signal. The cell signaling control is expected to contribute positively to the development of treatment for cardiovascular diseases.

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Obese people outnumber smokers two to one

New figures show that people who are obese now outnumber people who smoke two to one in the UK, and excess weight causes more cases of certain cancers than smoking, as the charity urges government action to tackle obesity.

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Why do mosquitoes choose humans?

Most of the 3,000+ mosquito species are opportunistic, but researchers are most interested in the mosquitoes that scientists call 'disease vectors' — carriers of diseases that plague humans — some of which have evolved to bite humans almost exclusively. One expert is trying to understand how the brain and genome of these mosquitoes have evolved to make them specialize in humans — including how

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Antifa attacks journalist. Should we ban wearing masks during protests?

Andy Ngo, a sub-editor at the online magazine Quillette, was attacked by masked activists as he was filming protests in Portland. The assailants haven't yet been identified, though police have released some photos of potential suspects. Some U.S. states and localities have banned public mask-wearing, while other courts have ruled such laws to be unconstitutional. None The conservative journalist

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An Astonishing Government Report on Conditions at the Border

Adults and children are strewn across the floor behind fencing; some are covered by mylar blankets—aluminum-foil-like sheets designed to keep the cold out in cool temperatures and to deflect the heat in warm temperatures—others are lying uncovered on the cement. Then there are the men and women and children behind glass windows, and the doors marked Holding cell . Some wear face masks, and one ma

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Physicists develop model that describes length growth in biological systems

"Grandmother, why do you have such big ears?" is one of the most well-known questions in literature, posed of course by Red Riding Hood as she hesitantly observes the wolf dressed in her Grandmother's clothes. Had Red Riding Hood been a physicist, she might well have asked: "Grandmother, why are your two ears exactly the same length?"

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Activity of fuel cell catalysts doubled

An interdisciplinary research team at the Technical University of Munich (TUM) has built platinum nanoparticles for catalysis in fuel cells: The new size-optimized catalysts are twice as potent as the best process commercially available today.

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Cool new wearable devices can do miracles for your health

From a small light-up pad that makes your bruise fade faster to a strip of gel that minimizes scars, new innovations to improve your health needs are on their way.

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Black (nano)gold to combat climate change

Global warming is a serious threat to the planet and living beings. One of the main causes of global warming is the increase in the atmospheric CO2 level. The main source of this CO2 is from the burning of fossil fuels in our daily lives (electricity, vehicles, industry and many more).

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U.N. chief heads back to Caribbean to raise the alarm about climate change, hurricanes

Almost two years after he visited the Caribbean to see for himself the devastation left by hurricanes Irma and Maria in Antigua and Barbuda and Dominica, United Nations Secretary-General Antonio Guterres is back—this time to meet with leaders of the 15-member Caribbean Community, Caricom, in St. Lucia.

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‘Filters Off!’ Chasing the Total Solar Eclipse in Chile

As the shadow of the moon swept across the Atacama Desert, the 52 Places Traveler stood celestially transfixed.

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Perfect timing: Making the 'switch' from juvenile to adult

Very little is known about how the onset of puberty is controlled in humans, but the discovery of a new gene in the roundworm C. elegans could be the "missing link" that determines when it's time to make this juvenile-to-adult transition. Two genes, LIN28 and MKRN3, are known to be associated with precocious puberty in humans, where juveniles as young as six may start developing adult features. Th

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The Pentagon Wants Its Own Orbital Space Station, Like a Death Star, But Not, Okay?

Reaching Out The U.S. military is in the early stages of sending a self-supporting, autonomous space station into orbit around the Earth. In its earliest stages, the space station will be small and (literally) inhospitable — the Pentagon’s Defense Innovation Unit (DIU) wants a dedicated orbital platform from which to conduct scientific experiments, reports Breaking Defense . But in the long run,

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Purple emperor butterfly makes 'official' Norfolk comeback

The purple emperor, the second largest butterfly in the UK, is "officially" back.

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Brain Corp., maker of robot janitors for Walmart, moving into European market

Brain Corp., which recently nearly tripled its orders from Walmart for self-driving, floor-scrubbing robots, is now making its first foray into Europe by opening a satellite office in the Netherlands.

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NASA peers into hurricane Barbara's heavy rainfall

The Global Precipitation Measurement mission or GPM core satellite passed over the storm and measured the rate in which rain was falling throughout it.

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Perfect timing: Making the 'switch' from juvenile to adult

Very little is known about how the onset of puberty is controlled in humans, but the discovery of a new gene in the roundworm C. elegans could be the "missing link" that determines when it's time to make this juvenile-to-adult transition. Two genes, LIN28 and MKRN3, are known to be associated with precocious puberty in humans, where juveniles as young as six may start developing adult features. Th

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Inspired by snails, researchers invent a reversible adhesive strong enough to hold a person

Superglue is incredibly useful—right until you end up attached to your craft project. But a new adhesive invented by University of Pennsylvania scientists is just as strong as standard superglue, and far more forgiving. The adhesive, based on snail slime, can be unattached and reattached over and over without losing its strength, and may save manufacturers from costly mistakes.

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US waste driving global garbage glut: study

The United States is driving a worldwide waste boom that poses a severe risk to human health, the environment and the economy, according to anew study of global garbage trends published Wednesday.

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3-D printing recreates ancient sculpture destroyed by ISIS

A figure of a roaring lion, about the size of a loaf of bread, is the latest step in the fight to preserve culture from conflict.

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Embattled Boeing to give $100 mn to 737 MAX crash victims' families

Boeing, under scrutiny after two crashes that claimed 346 lives, announced Wednesday it would give $100 million to communities and families affected by the 737 MAX disasters.

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Unprecedented Arctic megafires are releasing a huge amount of CO2

Dozens of wildfires are burning across the Arctic circle and have released as much CO2 in just one month as Sweden’s total annual emissions

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Deep Aging Clocks: The emergence of AI-based biomarkers of aging and longevity

The advent of deep biomarkers of aging, longevity and mortality presents a range of non-obvious applications.

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New high blood pressure guidelines could increase detection of gestational hypertension

Researchers at Brigham and Women's Hospital and colleagues conducted the first-ever study to evaluate the impact the 2017 ACA/AHA guidelines could have on detecting gestational hypertension.

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The Temptation of the Sorting Hat

Because sometimes tools designed to help us assess performance and potential just don’t — Read more on ScientificAmerican.com

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Amazon, Microsoft, And HP May Also Shift Production Outside China

China is the world’s manufacturing hub. Almost all of the products from major tech companies are manufactured there. This also leaves them in a bit of a sticky spot when trade tensions …

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You Should Really Read E. Jean Carroll’s Memoir

In the southeastern corner of Missouri is a tiny town named by a man, local lore has it, in honor of his girlfriend. She was Shawnee; the man in question realized, however, when it came time to make his tribute to her official, that he was unable to fully pronounce—or accurately spell—his beloved’s name. So the man paid her what he determined to be the next-best form of appreciation: He named the

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Daily briefing: UK university will ban lectures

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02078-6 “Soul-destroying” for lecturers and not great for learning anyway. Plus: climate change made the record-breaking heatwave in Europe at least five times more likely and psychology’s possible conflict-of-interest problem.

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Strange topological materials are popping up everywhere physicists look

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02062-0 ‘Fragile topology’ is the latest addition to a group of quantum phenomena that give materials exotic — and exciting — properties.

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This former playwright aims to turn solar and wind power into gasoline

Silicon Valley investors back experimental machine, which still needs to prove its economic worth

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Even if you don’t play contact sports, you could develop signs of traumatic brain injury

Study finds that 6% of population shows signs of chronic traumatic encephalopathy

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Huawei is giving $300 million a year to universities with no strings attached

Its new fundamental research division could help the company regain international favor and outmaneuver the US.

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The Moon Sits for Its Portrait

A trailblazing exhibition at the Metropolitan Museum explores our fascination with the moon, from the first time Galileo trained his telescope on it to the present.

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Russian Sub That Caught Fire Possibly Sent to Cut Internet Cables

Fire Down Below On Monday, a Russian submarine caught fire during a mission, killing 14 sailors on board. But the public didn’t find out about the incident until the next day, when Russia finally released a statement about the accident — though two days after the event, the nation still wouldn’t say exactly what kind of sub caught fire or whether it was nuclear-powered. A possible reason for Russ

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The weirdest things we learned this week: virgin births, composted humans, and naked South Pole scientists

Don't try this at home. (DepositPhotos/) What's the weirdest thing you learned this week? Well, whatever it is, we promise you'll have an even weirder answer if you listen to PopSci's hit podcast . The Weirdest Thing I Learned This Week hits Apple , Anchor , and everywhere else you listen to podcasts every Wednesday morning. It's your new favorite source for the strangest science-adjacent facts,

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Super-resolution microscopy illuminates associations between chromosomes

Thanks to super-resolution microscopy, scientists have now been able to unambiguously identify physical associations between human chromosomes. The findings have brought to light a new understanding to a curious observation first made more than 50 years ago.

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Trump’s Fourth of July Takeover Was Inevitable

If you fear that President Donald Trump has been underexposed lately—if you missed the back-to-back news conferences he gave in Asia over the weekend, or the 45 tweets he’s sent out since his return, or the footage of him speaking with reporters from the Oval Office on Monday afternoon, or the Fox News interview he gave later that night—know that, on the Fourth of July, he will come out of seclus

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B cells off rails early in lupus

Emory scientists could discern that in people with SLE, signals driving expansion and activation are present at an earlier stage of B cell differentiation than previously appreciated.

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Super-resolution microscopy illuminates associations between chromosomes

Thanks to super-resolution microscopy, scientists have now been able to unambiguously identify physical associations between human chromosomes. The findings have brought to light a new understanding to a curious observation first made more than 50 years ago.

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Neurosciences unlock the secret of the first abstract engravings

Long before Lascaux paintings, humans engraved abstract motifs on stones. The question is whether they are the result of unpurposive behaviour, the simple desire of imitating nature or endowed with meaning. A recent study is providing answers to this question. These prehistoric abstract patterns are processed by the same brain areas that recognize objects. They also activate a region of the left h

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Super-resolution microscopy illuminates associations between chromosomes

Thanks to super-resolution microscopy, scientists have now been able to unambiguously identify physical associations between human chromosomes. The findings have brought to light a new understanding to a curious observation first made more than 50 years ago.

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'Titans in a jar' could answer key questions ahead of NASA's space exploration

Researchers from Southern Methodist University (SMU) could help determine if Saturn's icy moon—Titan—has ever been home to life long before NASA completes an exploratory visit to its surface by a drone helicopter.

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Climate Change Made Europe's Mega-Heatwave Five Times More Likely

Scientists raced to study whether the scorching temperatures last week were linked to global warming — Read more on ScientificAmerican.com

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Facebook services back online after worldwide outage

Facebook said it was "back at 100 percent" Wednesday evening after an outage on all of its services affected users in various parts of the world.

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US auto industry legend Lee Iacocca dies age 94

Automobile industry legend Lee Iaococca, who is credited with creating the iconic Ford Mustang and saving Chrysler from bankruptcy, died Tuesday at the age of 94, US media reported.

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Are you sure it's burning mouth syndrome?

Not all burning mouths are the result of a medical condition known as 'burning mouth syndrome' (BMS) and physicians and researchers need better standards for an appropriate diagnosis, according to new research at the School of Dental Medicine at Case Western Reserve University.

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Perfect timing: Making the 'switch' from juvenile to adult

Very little is known about how the onset of puberty is controlled in humans, but the discovery of a new gene in the roundworm C. elegans could be the 'missing link' that determines when it's time to make this juvenile-to-adult transition.

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5 philosophy jokes that will actually teach you something

Philosophy can be difficult to understand, but humor can be a great way to approach it. Each of these jokes includes an explanation, so you can learn what they mean if you don't quite get them. Side effects of these jokes may include a sense of humor so dry it disproves Thales. Philosophy can be hard to learn. It's dry, often dull, and can be hard to get into if you don't already have some backgr

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Google has made a virtual soccer pitch to train AIs to play football

Google has created a virtual soccer training pitch for AIs to use to learn how to play football. The AIs will need to learn short-term control and high-level strategies

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Roskilde: Mens alle fester, holder et enkelt kort styr på det hele

Roskilde Festival er øl, festglade folk og musik. Men bag det hele ligger et GIS kort, som er stort set ukendt – men som får alt til at spille sammen.

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Satellite Image Captures a Total Solar Eclipse and a Hurricane in One Awesome Shot

The GOES-West weather satellite captured the gorgeous shot.

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Ebola outbreak shows science’s need to ‘nudge’

Human behaviour can be as destructive to human health as any deadly pathogen

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These scientists don’t think plants think

Stephen Fleischfresser assesses the latest views on an enduringly controversial idea.

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SMU's 'Titans in a jar' could answer key questions ahead of NASA's space exploration

Researchers from Southern Methodist University (SMU) could help determine if Saturn's icy moon — Titan — has ever been home to life long before NASA completes an exploratory visit to its surface by a drone helicopter.

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NASA peers into hurricane Barbara's heavy rainfall

The Global Precipitation Measurement mission or GPM core satellite passed over the storm and measured the rate in which rain was falling throughout it.

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Superbug virulence regulatory mechanism revealed: Pave ways for developing new antibiotics

As antibiotic resistance is growing and posing a threat on public health, developing new antibiotics has become more urgent than ever. Researchers at City University of Hong Kong (CityU) have recently revealed the virulence regulatory mechanism in Pseudomonas aeruginosa, a superbug which is common in patients with a weak immune system and is resistant to many antibiotics. The findings pave ways fo

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Androgen deprivation therapy associated with risk of alzheimer, dementia diagnoses in older men with prostate cancer

Data for 154,089 older men diagnosed with prostate cancer were used to analyze the association between androgen deprivation therapy, a hormone-suppressing therapy used to treat prostate cancer, and subsequent diagnosis of Alzheimer disease or dementia. Of the men, 62,330 (average age 76) received androgen deprivation therapy within two years of being diagnosed with prostate cancer and 91,759 men (

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Saving Beethoven

An optimized version of the CRISPR-Cas9 gene-editing system prevents hearing loss with no detectable off-target effects in so-called Beethoven mice, which carry a mutation that causes profound hearing loss in humans and mice alike. Results offer proof of principle for using the same gene-editing technique for other inherited human genetic diseases.

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The costs of cancer in 2015: 8.7 million years of life and $94 billion in lost earnings

Cancer took more than 8.7 million years of life and $94.4 billion in lost earnings among people ages 16 to 84 in the United States in 2015. The calculation comes from a new report by American Cancer Society researchers that appears early online in JAMA Oncology.

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Can aerobic, resistance exercise reduce excess fat around the heart?

Excessive fat tissue around the heart may be a risk factor for cardiovascular disease. This study looked at what effect aerobic and resistance exercise had on this fat tissue called epicardial and pericardial adipose tissue.

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Estimates of lost earnings from cancer deaths in US

Cancer has significant impact on the US economy, in part, because of lost productivity from premature deaths. This analysis estimated lost earnings for individuals ages 16 to 84 who died from cancer in 2015 by using data on cancer deaths, life expectancy and annual earnings.

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Bacteria engineered as Trojan horse for cancer immunotherapy

Researchers at Columbia Engineering and Columbia University Irving Medical Center announced today that they have engineered a strain of non-pathogenic bacteria that can colonize solid tumors in mice and safely deliver potent immunotherapies, acting as a Trojan Horse that treats tumors from within. The therapy led not only to complete tumor regression in a mouse model of lymphoma, but also signific

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Determined DNA hunt reveals schizophrenia clue

An 18-year study using the DNA of thousands of people in India has identified a new clue in the quest for causes of schizophrenia, and for potential treatments.This study identified a gene called NAPRT1 that encodes an enzyme involved in vitamin B3 metabolism.

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How aerobic exercise and resistance training preserves muscle mass in obese older adults

Researchers report July 3 in the journal Cell Metabolism that combining aerobic exercise and resistance training helps elderly obese individuals preserve muscle mass and reverse frailty as they work to lose weight. Based on a small clinical trial, the study showed that patients who completed these exercises had increased muscle protein synthesis and preserved muscle quality compared to control gro

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Plants don't think, they grow: The case against plant consciousness

If a tree falls, and no one's there to hear it, does it feel pain and loneliness? No, experts argue in an opinion article publishing on July 3 in the journal Trends in Plant Science. They draw this conclusion from the research of Todd Feinberg and Jon Mallatt, which explores the evolution of consciousness through comparative studies of simple and complex animal brains.

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Holograms from electrons scattered by light

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02016-6 The quantum interference of electrons that have been scattered by light has been used to produce holograms of the underlying electromagnetic fields — and might open up methods for studying materials at high temporal and spatial resolution.

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Miners Looking for Gemstones Find Ancient Sea Monster Instead

Miners digging for gemstones found something entirely different last month; the fossilized remains of an ancient sea monster.

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Your smartwatch could check if you are being productive enough

AIs don't think like children, but if they made a common assumption that children use whilst learning a language they would become better faster

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Upside Down portals from 'Stranger Things' are popping up in 'Fortnite'

"Fortnite" is one of the most popular games in the world, and companies are hoping to ride the wave by collaborating with publisher Epic Games.

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New study unravels protection mechanism in bacteria

Scientists at the University of Birmingham have shed fresh light on the mechanism used by certain types of bacteria to protect themselves against attack.

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The Science of Fireworks

We take you inside a single fireworks shell to show you how it all works. If you want to glimpse more than just the inner workings of one fireworks shell, you should check out this post by the… — Read more on ScientificAmerican.com

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It Takes a Village to Declassify an Error Bar

Identifying an interstellar meteorite—‘Oumuamua’s cousin—required a national-security waiver — Read more on ScientificAmerican.com

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New study unravels protection mechanism in bacteria

Scientists at the University of Birmingham have shed fresh light on the mechanism used by certain types of bacteria to protect themselves against attack.

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Group of biologists tries to bury the idea that plants are conscious

Environmental crisis clouding scientific objectivity about plants’ feelings, says botanist The gardening gloves are off. Frustrated by more than a decade of research which claims to reveal intentions , feelings and even consciousness in plants, more traditionally minded botanists have finally snapped. Plants, they protest, are emphatically not conscious. The latest salvo in the plant consciousnes

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New Weapons Against Cancer: Millions of Bacteria Programmed to Kill

Genetically modified microbes release “nanobodies” that alert the immune system to cancer in mice, scientists report.

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Plants don't think, they grow: The case against plant consciousness

If a tree falls, and no one's there to hear it, does it feel pain and loneliness? No, experts argue in an opinion article publishing on July 3rd in the journal Trends in Plant Science. They draw this conclusion from the research of Todd Feinberg and Jon Mallatt, which explores the evolution of consciousness through comparative studies of simple and complex animal brains.

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These scientists don’t think plants think

Stephen Fleischfresser assesses the latest views on an enduringly controversial idea.

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Plants don't think, they grow: The case against plant consciousness

If a tree falls, and no one's there to hear it, does it feel pain and loneliness? No, experts argue in an opinion article publishing on July 3rd in the journal Trends in Plant Science. They draw this conclusion from the research of Todd Feinberg and Jon Mallatt, which explores the evolution of consciousness through comparative studies of simple and complex animal brains.

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New study unravels protection mechanism in bacteria

Scientists at the University of Birmingham have shed fresh light on the mechanism used by certain types of bacteria to protect themselves against attack.

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Hospitals address opioid crisis via stewardship with strong pharmacist involvement

A survey of health-system pharmacy directors released today found that most large health systems have active stewardship programs to prevent the misuse of opioids — with pharmacists playing a key role. The findings are part of the National Survey of Pharmacy Practice in Hospital Settings, published in AJHP, the journal of ASHP (American Society of Health-System Pharmacists). The survey also explo

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Activity of fuel cell catalysts doubled

An interdisciplinary research team at the Technical University of Munich (TUM) has built platinum nanoparticles for catalysis in fuel cells: The new size-optimized catalysts are twice as good as the best process commercially available today.

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Physicists develop model that describes length growth in biological systems

One of science's unsolved puzzles is that concerning the growth of biological systems. Whether it's a microscopic protozoa or a blue whale, all living systems grow. Physicists at Saarland University have now discovered a mechanism that could well provide a means to explain this mystery. They have developed a mathematical model that offers a precise explanation of growth in biological systems.

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Risks of Controversial Geoengineering Approach "May Be Overstated"

Halving the amount of aerosols injected into the atmosphere could reduce global temperatures and temper side effects — Read more on ScientificAmerican.com

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It Takes a Village to Declassify an Error Bar

Identifying an interstellar meteorite—‘Oumuamua’s cousin—required a national-security waiver — Read more on ScientificAmerican.com

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Trump Wants Tanks on the National Mall. What Could Go Wrong?

Hello, comrades! Happy Fourth of July, or should I say, Happy 45th President of July! How fortunate we are to see our Tremendous Nation’s military hardware as we celebrate the 240th-ish anniversary of something or the other, and the third year of our Amazing President! Of course, our Great Hero Farmers are going bankrupt and our Treasonous Justice Department is engaging in ongoing Presidential Ha

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Astronomers Are Baffled by the Most Bizarre Star Yet

Unusual dips of light observed by the Kepler space telescope have so far confounded attempts at an explanation — Read more on ScientificAmerican.com

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Could Lab-Grown Brains Develop Consciousness?

submitted by /u/dwaxe [link] [comments]

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What Do a Toy Store and a Tech Accelerator Have in Common? Cloud-Based Tech.

Your Clouds Can (YCC) 2019 was an immersive experience unlike any conference. Its purpose? To understand how seemingly traditional businesses can utilize data and cloud based technology to reimagine themselves and grow. On June 5th, Futurism and IBM took attendees on a journey – but, unlike traditional conferences, they brought the audience members directly to the speakers’ headquarters. They imm

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Social context influences decision-makers' willingness to take risks

Do differences in performance have an impact on the appetite for risk-taking in decision-makers? Economists at the University of Göttingen have addressed this question. The result of their study is that people's willingness to take risks increases as soon as they get a lower return than other people with whom they compare themselves. At the same time, decision-makers take lower risks if they get a

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CEO political activism: Jobseekers want bosses who take a stand

Chief executives who speak out on political issues and take a principled stance are increasingly sought out by jobseekers who believe such behaviour signals fair treatment, respect for employees, and a more responsible vision beyond nurturing the bottom line, new research shows.

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The energy system of the future and Power-to-X

In a joint research project of five Swiss competence centres for energy research, scientists of the Paul Scherrer Institute PSI and colleagues have prepared a white paper on "Power-to-X" for consideration by the Swiss Federal Energy Research Commission (CORE). The goal of the white paper is to gather together the most important insights available on Power-to-X technologies. Among other things, the

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Proteiner fångade i glas visar vägen mot nya läkemedel

Idag används flera olika metoder för att avbilda proteiner men ingen metod erbjuder fullgoda möjligheter för att studera enskilda membranproteiner i deras naturliga miljö. Forskargruppen på Chalmers har nu framgångsrikt använt atomsondstomografi för att avbilda och studera proteiner. Metoden väcker uppmärksamhet eftersom tekniken fram till idag endast har använts för att karakterisera metaller oc

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Black (nano)gold combat climate change

By using the techniques of nanotechnology, we transformed golden gold to black gold, by simply changing the size and gaps between gold nanoparticles. Now, like real trees, where they use CO2, sunlight and water to produce food, our developed black gold act like an artificial tree and use CO2, sunlight and water to produce fuel. Notably, black gold can also use to convert sea water into drinkable w

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Blood pressure drug linked with increased risk of bowel condition

A type of blood pressure lowering medication, called a calcium-channel blocker, may be linked with an increased risk of a type of bowel condition called diverticulosis.

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Treatment targeted at a genetic mutation relieves psychosis symptoms

Treatment of psychosis can be targeted to a specific genetic mutation in patients with psychotic disorders, according to a study in Biological Psychiatry, published by Elsevier. The study provides a proof-of-principle demonstration that treatments can be tailored to a specific genotype, rather than diagnosis, to relieve symptoms. The findings also link an individual structural mutation to the unde

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Pediatric cancers: Towards more targeted therapy

UCLouvain researcher Anabelle Decottignies has found a possible strategy for killing cancer cells, especially in children, without affecting healthy cells, as reported in the scientific journal Molecular Cell.

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DGIST Discovers control of cell signaling using a cobalt (iii)-nitrosyl complex

Joint research team of Professors Jaeheung Cho and Daeha Seo in the Department of Emerging Materials Science developed a technology to control the generation of nitric oxide in cells. Proposed the possibility of additional research related to cell signal transfer.

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A vision for the future of Sierra Leone | Julius Maada Bio

When Julius Maada Bio first seized political power in Sierra Leone in 1996, he did so to improve the lives of its citizens. But he soon realized that for democracy to flourish, its foundation needs to be built on the will of the people. After arranging an election, he voluntarily gave up power and left Africa. Twenty years later, after being democratically elected president of Sierra Leone, he ref

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White Paper: These 12 Principles Are Shaping the Future of Autonomous Cars

As nice as it’d be to have the option of catching up on some reading — or sleep — while an autonomous vehicle drives you to work, the real draw of self-driving cars is the idea that they’ll be safer drivers than whoever just cut you off in the exit lane with inches to spare. After all, if the vast majority of traffic accidents are caused by human error, taking humans out of the equation should sa

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Maize-centric diet may have contributed to ancient Maya collapse

The question of how to best adapt to extreme climate is a critical issue facing modern societies worldwide. In "The Role of Diet in Resilience and Vulnerability to Climate Change among Early Agricultural Communities in the Maya Lowlands," published in Current Anthropology, authors Claire Ebert, Julie Hoggarth, Jaime Awe, Brendan Culleton, and Douglas Kennett examine the role of diet in the ability

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Astronomers Are Baffled by the Most Bizarre Star Yet

Unusual dips of light observed by the Kepler space telescope have so far confounded attempts at an explanation — Read more on ScientificAmerican.com

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8 ways to avoid food poisoning

Poison control experts have advice for how to avoid food poisoning at your Fourth of July BBQs and picnics. “Forgetting about food safety is a recipe for disaster,” says Diane Calello, executive and medical director of the New Jersey Poison Control Center at Rutgers New Jersey Medical School. “Don’t prepare food if you have any kind of respiratory illness or infection, as this puts your guests at

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Two new species of parasitic wasps described from an altitude of over 3,400 m in Tibet

Specimens kept in the collection of the Institute of Beneficial Insects at the Fujian Agriculture and Forestry University (FAFU, China) revealed the existence of two previously unknown species of endoparasitoid wasps. Originally collected in 2013, the insects are known to inhabit prairies and bushes at above 3,400 m, which is quite an unusual altitude for this group of wasps.

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Old-growth forest may provide valuable biodiversity refuge in areas at risk of severe fire

New findings show that old-growth forests, a critical nesting habitat for threatened northern spotted owls, are less likely to experience high-severity fire than young-growth forests during wildfires. This suggests that old-growth forest could be leveraged to provide valuable fire refuges that support forest biodiversity and buffer the extreme effects of climate change on fire regimes in the Pacif

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Two new species of parasitic wasps described from an altitude of over 3,400 m in Tibet

Specimens kept in the collection of the Institute of Beneficial Insects at the Fujian Agriculture and Forestry University (FAFU, China) revealed the existence of two previously unknown species of endoparasitoid wasps. Originally collected in 2013, the insects are known to inhabit prairies and bushes at above 3,400 m, which is quite an unusual altitude for this group of wasps.

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Old-growth forest may provide valuable biodiversity refuge in areas at risk of severe fire

New findings show that old-growth forests, a critical nesting habitat for threatened northern spotted owls, are less likely to experience high-severity fire than young-growth forests during wildfires. This suggests that old-growth forest could be leveraged to provide valuable fire refuges that support forest biodiversity and buffer the extreme effects of climate change on fire regimes in the Pacif

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This Room-Sized Device Could Create Artificial Gravity in Space

Weight Gain You’ve probably seen one featured in a science fiction movie, including “2001: A Space Odyssey” — massive centrifuge-like space stations that spin around a center point to create the sensation of artificial gravity for off-world travelers. While we have yet to build such a large system in open space, researchers from University of Colorado at Boulder have decided to miniaturize the ef

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The Paradox of Madonna’s Gun-Control Music Video

Madonna has presented herself as a fierce warrior against gun violence lately, and the result largely has been offensive to people who’ve survived gun violence. Last week, she released a music video that depicted a massacre at a discotheque, and Patience Carter, who lived through the shooting at Pulse nightclub in Orlando, Florida, tweeted , “I applaud the attempt, but I am truly disturbed.” Bran

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Packaging-free shops may tackle plastic but risk increasing food waste

Shops that let you bring your own containers aim to tackle the plastic packaging scourge, but they may not be the perfect solution

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Two new species of parasitic wasps described from an altitude of over 3,400 m in Tibet

Specimens kept in the collection of the Institute of Beneficial Insects at the Fujian Agriculture and Forestry University (China) revealed the existence of two previously unknown species of endoparasitic wasps. Looking very similar to each other, yet clearly distinct from species in other wasp genera, both have once been collected from prairies and bushes in high-altitude areas in Tibet, China. Th

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Taking to the treadmill can ease period pain

A treadmill exercise regime can reduce period pain and improve long-term quality of life.

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Quorn protein builds muscle better than milk protein

A study from the University of Exeter has found that mycoprotein, the protein-rich food source that is unique to Quorn products, stimulates post-exercise muscle building to a greater extent than milk protein.

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Imprinted spheres fight breast cancer

A particularly aggressive, metastasizing form of cancer, HER2-positive breast cancer, may be treated with nanoscopic particles "imprinted" with specific binding sites for the receptor molecule HER2. As reported by Chinese researchers in the journal Angewandte Chemie, the selective binding of the nanoparticles to HER2 significantly inhibits multiplication of the tumor cells.

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Ultra-small nanoprobes could be a leap forward in human-machine interfaces

Machine enhanced humans — or cyborgs as they are known in science fiction — could be one step closer to becoming a reality, thanks to new research from the University of Surrey and Harvard University.

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Graphenes now go monolayer and single crystalline

IBS-CMCM scientists have reported a truly single layer (i.e., adlayer-free) large area graphene film on large area copper foils. This uniform, 'perfect' single layer, single crystal graphene is expected to find use as an ultrathin support material for high-resolution transmission electron microscopy imaging, and in optical devices. Also as an appropriate graphene to achieve extremely uniform funct

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Old-growth forest may provide valuable biodiversity refuge in areas at risk of severe fire

New findings show that old-growth forests, a critical nesting habitat for threatened northern spotted owls, are less likely to experience high-severity fire than young-growth forests during wildfires. This suggests that old-growth forest could be leveraged to provide valuable fire refuges that support forest biodiversity and buffer the extreme effects of climate change on fire regimes in the Pacif

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The Quantum Theory That Peels Away the Mystery of Measurement

Imagine if all our scientific theories and models told us only about averages: if the best weather forecasts could only give you the average daily amount of rain expected over the next month, or if astronomers could only predict the average time between solar eclipses. In the early days of quantum mechanics, that seemed to be its inevitable limitation: It was a probabilistic theory, telling us on

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Seals remember what they just did – but only for about 18 seconds

Seals and sea lions can repeat their last action on command, as long as they are asked to do so within 18 seconds , hinting at a degree of self-awareness

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US media sector braces for brutal year for jobs

The struggling US media industry is facing its worst year for job layoffs in a decade as news organizations continue to cut staff and close shop, according to a new survey.

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'Tsunami' on a silicon chip: a world first for light waves

A tsunami holds its wave shape over very long distances across the ocean, retaining its power and 'information' far from its source.

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Lithuania declares emergency as drought hits farmers

Lithuania declared an emergency on Wednesday as a severe drought hit the Baltic EU state, threatening to slash this year's harvest by up to half.

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Milk and dairy products can help prevent chronic disease

Ángel Gil, Professor of Biochemistry and Molecular Biology at the University of Granada, has recently coordinated a study reviewing worldwide scientific literature on the role of dairy products in health and in the prevention of chronic diseases (cardiovascular, metabolic syndrome, colon or bladder cancer, and type 2 diabetes). The review also covers the effects of dairy products on growth, bone m

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World first: Homing instinct applied to stem cells show cells 'home' to cardiac tissue

In a world first, scientists have found a new way to direct stem cells to heart tissue. The findings, led by researchers at the University of Bristol and published in Chemical Science, could radically improve the treatment for cardiovascular disease, which causes more than a quarter of all deaths in the UK (1).

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Oxford: Robots will take 20 million manufacturing jobs by 2030

submitted by /u/gone_his_own_way [link] [comments]

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Vilde ideer om vand undersøges på DTU

PLUS. Eksperimenter viser, at egenskaberne ved vand kan påvirkes med ultrasvage elektromagnetiske felter. Årsagen hertil nøjes DTU-forsker endnu med at gisne om, men han mener, perspektiverne er store.

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Could Lab-Grown Brains Develop Consciousness?

There’s a very un-sexy view of consciousness: our rich, meaningful inner experience of self and other is nothing but electrical and chemical chattering inside our brains. If you, like many scientists, subscribe to this theory, then a difficult question naturally follows: at what point does electro-chemical activity in dissected brain-like tissue become conscious? Yes, I’m talking about the classi

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Best seat in the house

Thousands gather to watch a total eclipse of the sun.

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Mechanism behind low cancer occurrence in bats signals potential treatment strategies for humans

Researchers from Duke-NUS Medical School have uncovered a potential mechanism behind cancer suppression in bats that may lead to future therapies for human cancers. The research shows that bat cells accumulate less toxic chemicals than human cells, where these chemicals are moved out of the system mediated by a cell surface pump protein, known as ABCB1, that is more abundant and widely distributed

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First time human-on-a-chip predicts in vivo results based on in vitro model

In a study published in Nature Scientific Reports, in collaboration with AstraZeneca, Hesperos described how they used a pumpless heart model and a heart:liver system to evaluate the temporal pharmacokinetic/pharmacodynamic relationship for terfenadine, an antihistamine that was banned due to toxic cardiac effects, as well as determine its mechanism of toxicity. The findings further support the po

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Cosmic Fireworks Glow Red, White and Blue in Epic Hubble Photo

In the 1840s, a mysterious explosion made Eta Carinae the second-brightest star in the sky. Now, NASA has discovered a peculiar secret in the violent star's red, white and blue fallout.

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When is it time for seniors to forgo cancer screening?

New research documents unnecessary cancer screenings for older adults with less than 10 years life expectancy, as well as how to communicate about foregoing such tests. Over the past decades, the public has repeatedly heard the idea that all adults should get regularly screened for cancer—with mammograms, colonoscopies, and prostate specific antigen blood tests. But current clinical guidelines re

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Waterproof artificial synapses for pattern recognition in organic environments

Most artificial intelligence (AI) systems try to replicate biological mechanisms and behaviors observed in nature. One key example of this is electronic synapses (e-synapses), which try to reproduce junctions between nerve cells that enable the transmission of electrical or chemical signals to target cells in the human body, known as synapses.

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How poor communication causes catheter problems

Most problems with catheter use stem from poor physician-nurse communication, according to a new study. Indwelling devices like catheters cause roughly 25 percent of hospital infections, but ongoing efforts to reduce catheter use and misuse haven’t succeeded as much as health care workers would like. Milisa Manojlovich, a professor at the School of Nursing at the University of Michigan, says the

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America’s first rocket man, the rise of cryptocurrencies, and artificial intelligence reconsidered: Books in brief

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02044-2 Barbara Kiser reviews five of the week’s best science picks.

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Binary stars with unexplainable dimming pattern

A team of researchers from the U.S., Denmark and the U.K., working with a group at NASA's Ames Research Center, has found a binary star system that dims unpredictably. They have written a paper describing their findings and have posted it on the arXiv preprint server and also on Oxford's Monthly Notices of the Royal Astronomical Society.

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From Shark Bay seagrass to Stone Age Scotland, we can now assess climate risks to World Heritage

Climate change is the fastest-growing global threat to World Heritage. However, no systematic approach to assess the climate vulnerability of each particular property has existed—until now.

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Clickety clack, let's look back: Typewriters return

For most of us, the clickety clack of a manual typewriter—or the gentler tapping of the IBM Selectric—are but memories, if we've heard them at all.

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'Tsunami' on a silicon chip: a world first for light waves

A collaboration between the University of Sydney Nano Institute and Singapore University of Technology and Design has for the first time manipulated a light wave, or photonic information, on a silicon chip that retains its overall 'shape'. This foundational work is important because most communications infrastructure still relies on silicon-based devices for propagation and reception of informatio

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Up to 30% of children carry a gene variant that may increase susceptibility to methylmercury

A study with 2,147 children explored the association between prenatal exposure to methylmercury, intellectual coefficient at 8 years of age, and genotype

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Social context influences decision-makers' willingness to take risks

Do differences in performance have an impact on the appetite for risk-taking in decision-makers? Economists at the University of Göttingen have addressed this question. The result of their study is that people's willingness to take risks increases as soon as they get a lower return than other people with whom they compare themselves. At the same time, decision-makers take lower risks if they get a

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Winter monsoons became stronger during geomagnetic reversal

New evidence suggests that high-energy particles from space known as galactic cosmic rays affect the Earth's climate by increasing cloud cover, causing an 'umbrella effect'.

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Smokers three times likely to die from heart disease

Smoking is killing at least 17 Australians a day from preventable heart attacks, strokes and other cardiovascular conditions, new research led by The Australian National University (ANU) has found.

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CEO political activism — Jobseekers want bosses who take a stand

Chief executives who speak out on political issues and take a principled stance are increasingly sought out by jobseekers who believe such behaviour signals fair treatment, respect for employees, and a more responsible vision beyond nurturing the bottom line, new research shows.

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Maize-centric diet may have contributed to ancient Maya collapse

Researchers look at the role of diet in the ability of the ancient Maya to withstand periods of severe climatic stress. They found that an increase in the elite Maya's preference for a maize-based diet may have made the population more vulnerable to drought, contributing to its societal collapse.

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Researchers selectively eliminate cells that express the oncogene RAS

The RAS oncogene is activated in 30 percent of human cancers, and results in the proliferation and transformation of tumor cells. No effective inhibitor has been found for this protein to date.

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Artificial membrane binding proteins to direct stem cells to the myocardium

In a world first, scientists have found a new way to direct stem cells to heart tissue. The findings, led by researchers at the University of Bristol and published in Chemical Science, could radically improve the treatment for cardiovascular disease, which causes more than a quarter of all deaths in the UK.

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Researchers selectively eliminate cells that express the oncogene RAS

The RAS oncogene is activated in 30 percent of human cancers, and results in the proliferation and transformation of tumor cells. No effective inhibitor has been found for this protein to date.

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Artificial membrane binding proteins to direct stem cells to the myocardium

In a world first, scientists have found a new way to direct stem cells to heart tissue. The findings, led by researchers at the University of Bristol and published in Chemical Science, could radically improve the treatment for cardiovascular disease, which causes more than a quarter of all deaths in the UK.

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Allotment soil is safer than U.K. national guidelines suggest

With the rise in popularity of people growing their own fruit and vegetables, it may be surprising to know that many urban allotments have soil with lead levels above UK guidance values.

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What Kind of Movie Ari Aster Wanted Midsommar to Be

This story contains mild spoilers for the film Midsommar . Ari Aster is not afraid to talk about how personal his filmmaking is. Maybe he should be; anyone who’s seen his debut feature Hereditary , and its follow-up, Midsommar (which opens in theaters today), might expect the director to be as bleak and bizarre as his creations. But though Aster has described the harrowing Hereditary as a family

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Image: Suomi NPP satellite captures ongoing fires in Alaska

There are many fires ongoing in the state of Alaska, but two of the largest are visible in this satellite image—Hess Creek Fire and Swan Lake Fire.

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SpaceX has lost contact with three of its Starlink satellites

On May 23rd, 2019, SpaceX launched the first batch of its Starlink constellation, a fleet of satellites that will fulfill Elon Musk's promise to provide broadband satellite-internet access to the entire planet. The deployment of these 60 satellites was the first in a series of six planned launches that would see around 720 satellites orbiting at an operational altitude of 550 km (340 mi).

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Carbon dioxide levels and climate change: Is there really a controversy?

The relationship between atmospheric CO2 levels and climate change is often perceived as a controversial subject. While there's no real disagreement among climate scientists—around 90% fully agree that human activity is clearly responsible for climate change—in the United States in 2016, barely 50% of the general public came to the same conclusion. Adding to the general confusion, highly active "c

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How anglers are changing the catchability of fish

For many outdoor enthusiasts, fishing borders on an obsession—the thrill of the chase may be just as rewarding as landing a big catch.

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How anglers are changing the catchability of fish

For many outdoor enthusiasts, fishing borders on an obsession—the thrill of the chase may be just as rewarding as landing a big catch.

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Mapping Apps for Camping and Hiking: AllTrails, Gaia, Topo Maps+

Don't lose yourself out there. Download one of these trail mapping apps to make sure you can always find your way, whether you have cell service or not.

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What Makes a Good Cooler (According to Physics)?

You're not so much keeping the "coldness" in, but keeping the heat out. How well a cooler can do this will depend on three key factors: insulation, air, and ice.

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NASA Needs to Out-Crazy Elon Musk

Opinion: The once-revolutionary space agency is being upstaged by unapologetic capitalists. Here's how it can reclaim its relevance.

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Lunar and solar eclipses make animals do strange things

For most animals, the structure of their day—and indeed their year—depends on the light-dark cycle. These regular and rhythmic cycles in the length of days tell animals when they should be foraging, when they should be asleep, when it's time to migrate and when it's time to breed. Animals can tell all this from how many hours of daylight they experience, but the moon's cycles also strongly influen

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Image: Radio frequency model of Europe's future Meteosat Third Generation Imager (MTG-I) satellite

This mesh-based model of Europe's future Meteosat Third Generation Imager (MTG-I) satellite has helped select the optimal location of the radio frequency antennas used to send it commands and downlink mission telemetry.

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Scientists find carbon from thawing permafrost is released into the atmosphere at higher rates than previously thought

For years, scientists have pointed to warming permafrost in the Arctic tundra as a source for increased carbon in the atmosphere; as this soil warms, it releases greenhouse gases that have long been trapped in frozen ground.

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Blue 'noctilucent' clouds are appearing further south than ever seen before, and pollution may be a cause

Cloud watchers have recently been given record-breaking glimpses of the rarest clouds in the skies. Stunning rippled blue clouds have been forming in the highest reaches of the atmosphere over Europe and the U.S.. These clouds are normally only seen around the poles, but this summer is set to be the best observing season in years—they have already been seen at the lowest latitudes ever recorded.

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Four surprising technological innovations that came out of the Apollo moon landings

NASA's Apollo programme was one of the most challenging technological achievements in the 20th century. Beyond the space race and exploration, it contributed to several inventions and innovations that are still having an impact on our lives. But at the same time, there are several myths regarding what technologies actually came out of it.

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Smartphone network helps uncover hundreds of anti-cancer molecules in food

A crowdsourcing project which uses thousands of idling smartphones has helped to uncover anti-cancer properties of everyday foods and medicines.

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Lunar and solar eclipses make animals do strange things

For most animals, the structure of their day—and indeed their year—depends on the light-dark cycle. These regular and rhythmic cycles in the length of days tell animals when they should be foraging, when they should be asleep, when it's time to migrate and when it's time to breed. Animals can tell all this from how many hours of daylight they experience, but the moon's cycles also strongly influen

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The Doctor Who Beat Ebola–and Inspires Other Survivors to Care for the Sick

Maurice Kakule Mutsunga has started a motorcycle ambulance service and is working to dispel rumors about the virus — Read more on ScientificAmerican.com

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DNA is DNA: The anti-GMO movement ignores basic genetics

Genetic engineering (GE) is simultaneously one of the most misunderstood technological marvels we have invented. The internet is full of articles and videos denouncing the supposed evils of genetically modified organisms (GMOs) with one of the most common arguments claiming … Continue reading →

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How planting trees can improve water quality

New research offers a hard link between reforestation of marginal, degraded, or abandoned agricultural land and significant benefits in water quality. This relationship, argues Arturo Keller, a professor of environmental biogeochemistry at the University of California, Santa Barbara, lends itself toward a program that incentivizes facilities that discharge pollutants, and local farmers to plant t

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Kendt stof giver penicillin superkræfter mod MRSA

Dansk-britisk studie viser, at helt almindelig penicillin kan slå MRSA ned. Tricket er samtidig at give patienterne clavulansyre.

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Collaborative Telepresence Could Render Distance (Relatively) Meaningless

Soon participants in virtual gatherings will feel like they are physically together — Read more on ScientificAmerican.com

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Collaborative Telepresence Could Render Distance (Relatively) Meaningless

Soon participants in virtual gatherings will feel like they are physically together — Read more on ScientificAmerican.com

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A solar panel that unfolds in sunlight could power spacecraft

Special polymers that expand when heated allow a solar panel to unfurl when it is exposed to sunlight, which could be useful for solar-powered spacecraft

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Quakes on Mars May Share a Common Mechanism with Human-Caused Earthquakes

Quakes on Mars May Share a Common Mechanism with Human-Caused Earthquakes Pressurized water may cause quakes on Mars the same way fracking and wastewater injection trigger quakes on Earth. 00-marsquake.jpg Image credits: Sayan Puangkham/ Shutterstock Space Wednesday, July 3, 2019 – 08:15 Charles Q. Choi, Contributor (Inside Science) — Quakes on Mars might sometimes result from aquifers being squ

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Researchers find targeted treatment that reduces symptoms of psychosis

Treatment for psychosis can be targeted to a specific structural mutation, according to a new study published by researchers from McLean Hospital.

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Baidu chief doused with water at AI event

A bottle of water was poured on to Baidu's chief executive during a presentation.

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Water seekers

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02048-y Caught in a trap.

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Asteroid impact, Titan mission and Soviet emissions

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02039-z The week in science: 28 June–4 July 2019.

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Smarter Fertilizers Can Reduce Environmental Contamination

New formulations deliver nourishment on demand — Read more on ScientificAmerican.com

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Facebook’s New Content Moderation Tools Put Posts in Context

The audit noted that asking reviewers "to consider whether the user was condemning or discussing hate speech, rather than espousing it, may reduce errors.”

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Spider-Man Is Back … But Why All Dressed in Black?

The new cinematic Spider-Man follows the comic-book tradition of putting characters in new clothes to illustrate character development.

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Image of the Day: Jelly Bot

See a tiny, jellyfish-like robot swim, burrow, and carry beads.

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Graphenes now go monolayer and single crystalline

IBS-CMCM scientists have reported a truly single layer (i.e., adlayer-free) large area graphene film on large area copper foils. They refined the chemical vapor deposition (CVD) growth method by eliminating all carbon impurities inside the copper foils on which graphene is grown. This uniform, "perfect" single layer, single crystal graphene is expected to find use as an ultrathin support material

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Code in Chinese surveillance app analysed

Computer security researchers at Ruhr-Universität Bochum (RUB), in collaboration with the association of investigative journalists from NDR and Süddeutsche Zeitung (SZ), have analysed the Chinese surveillance app that travellers must install on their phones when crossing the border from Kyrgyzstan to China. The researchers report that the app scans the phone for approximately 73,000 specific files

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Processed Foods and Autism

Reports of a "link" between processed food and autism highly misrepresent the actual findings of an in-vitro study.

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Smarter Fertilizers Can Reduce Environmental Contamination

New formulations deliver nourishment on demand — Read more on ScientificAmerican.com

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Remembering Apollo 11: What to Watch and Listen To

As the 50th anniversary of the moon landing approaches, these movies, television shows and podcasts help shine a light on the story.

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iOS 13: New iPhone update fixes awkward video calls and makes sure users look like they're paying attention

'FaceTime Attention Correction' will make you look like you're maintaining eye contact even when you are not

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Image: 400-hectare wildfire is largest ever in German state

On 30 June, a wildfire broke out at a military training site in Lübtheen, in northern Germany.

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A third CRISPR baby may have already been born in China

Another genetically edited baby is due, but the world may never learn of its birth if the Chinese government decides to keep it a secret.

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Could this newly discovered protein help treat Parkinson's?

Researchers have identified a protein that could reduce toxic aggregations in the brain. Their finding could lead to new therapies for Parkinson's disease.

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Winter monsoons became stronger during geomagnetic reversal

New evidence suggests that high-energy particles from space known as galactic cosmic rays affect the Earth's climate by increasing cloud cover, causing an "umbrella effect."

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New study analyzes land tenure in Ghana

In August 2018, the local government of Accra, Ghana, in West Africa, appropriated 1,800 homes for demolition to make way for, among others, tomato retailers. Officials had already begun plotting the land for its new use when residents of the largely poor neighborhood erupted in protest, to no avail.

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Being certain about uncertainty

Non-scientists—legislators, judges and juries—are often called upon to reach scientific conclusions.

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Every dog has its day, but it's not the Fourth of July

The Fourth of July can be a miserable day for dogs. The fireworks make scaredy-cats out of many canines.

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NASA's ECOSTRESS maps European heat wave from space

Europe's massive heat wave is on its way out—and it's leaving a slew of broken temperature records in its wake. Many countries were gripped by temperatures above 104 Fahrenheit (40 degrees Celsius) between June 26 and June 30. According to the World Meteorological Organization, June 2019 is now the hottest month on record for the continent as a whole.

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Scientists scramble to build payload for 2021 moon landing

Scavenging spare parts and grabbing off-the-shelf hardware, University of California, Berkeley, space scientists are in a sprint to build scientific instruments that will land on the moon in a mere two years.

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The 'freak wave' myth

As a nation "girt by sea," Australians live with the joy and risks of the ocean.

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How big data can help you choose better health insurance

There are plenty of easy consumer choices. Paper clips: easy. Dish sponges: easy. Those products sit at one end of the spectrum. At the other end, impossibly distant, is health insurance.

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Artificial gravity breaks free from science fiction

Artificial gravity has long been the stuff of science fiction. Picture the wheel-shaped ships from films like 2001: A Space Odyssey and The Martian, imaginary craft that generate their own gravity by spinning around in space.

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Discovery of rare lava lake on remote sub-Antarctic island

A team of scientists has discovered a rare lava lake on a remote and inaccessible sub-Antarctic island. There are around 1500 land-based volcanoes on Earth, but despite the popular perception of steaming bubbling lava pools in their craters this volcano in the South Sandwich Islands is only the 8th to be identified worldwide to have a persistent lava lake.

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Neutral evolution shapes lifespan and aging

Different African killifish species vary extensively in their lifespans—from just a few months to several years. Scientists from the Max Planck Institute for Biology of Ageing in Cologne investigated how different lifespans have evolved in nature and discovered a fundamental mechanism by which detrimental mutations accumulate in the genome causing fish to age fast and become short-lived. In humans

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Every dog has its day, but it's not the Fourth of July

The Fourth of July can be a miserable day for dogs. The fireworks make scaredy-cats out of many canines.

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Neutral evolution shapes lifespan and aging

Different African killifish species vary extensively in their lifespans—from just a few months to several years. Scientists from the Max Planck Institute for Biology of Ageing in Cologne investigated how different lifespans have evolved in nature and discovered a fundamental mechanism by which detrimental mutations accumulate in the genome causing fish to age fast and become short-lived. In humans

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Reunited: Two halves of historic scroll severed by warfare

Paul Mirecki found himself in the middle of an Indiana Jones-style quest involving looted antiquities.

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Water drives explosive eruptions: Magma is wetter than we thought

Volatile elements in magma, primarily water, drive explosive volcanic eruptions. The tricky part is determining just how much volatile content was present before the eruption took place. This is especially difficult when the only evidence scientists have to go on is the end product after all the volatiles have been lost.

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Why Blue Fireworks Are So Rare

Here's the chemistry behind those awesome fireworks shows.

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3rd Mysterious Deep-Space Flash Traced to Host Galaxy

Cosmic explosion was traced to a big galaxy about 7.9 billion light-years away from Earth.

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Ethics in the Age of Artificial Intelligence

If we don’t know how AIs make decisions, how can we trust what they decide? — Read more on ScientificAmerican.com

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Exotic 'Early Dark Energy' Could Be the Missing Link That Explains the Universe's Expansion

Measures of the universe's expansion taken from different sources don't match. An exotic form of dark energy particles could be the reason why.

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Why Is It 'Snowing' Salt in the Dead Sea?

Drifts of salt up to 13 feet thick collect on the sea bottom.

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The Sheriff Who’s Defying ICE

CHARLOTTE, N.C.—In 2006, Luis Pineda-Ancheta was arrested in Arizona; charged with illegal entry into the United States, a civil offense; and deported back to his native Honduras. At some point in the next 13 years—authorities don’t know when—he returned to the U.S. and ended up in North Carolina. In April, a woman reported to police in Charlotte that Pineda-Ancheta had grabbed her and threatened

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America’s Asylum System Is Profoundly Broken

A 25-year-old man from El Salvador tried to swim with his daughter across the Rio Grande to Brownsville, Texas. Father and daughter were caught in the current, and drowned. Their bodies washed ashore on the Mexican side of the river, in an image that has seized the attention of the world. But other sights, not photographed, are equally horrifying. A woman from Punjab, India, tried to walk her 6-y

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Emma Chamberlain and the Rise of the Relatable YouTuber

The most talked-about teen influencer in the world doesn't airbrush her photos. She doesn’t have a team of editors and photographers following her around and taking aspirational “ plandids .” In fact, she doesn’t make her life seem very aspirational at all: In many of her videos, she looks like she just rolled out of bed. Emma Chamberlain shuns makeup, sometimes skips a shower, and doesn’t seem t

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A Startling Spike on Mars

If humans ever discover life on Mars, this is how it might start: with a breaking-news alert heralding a startling development well beyond Earth. On a recent Saturday afternoon, The New York Times sent a bulletin: “Mars is belching a large amount of methane gas. It’s a sign of possible life on the red planet.” NASA quickly published a press release acknowledging the detection, which, the Times ha

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Everything You Should Read, Watch, and Listen To Over the July 4th Weekend

You have a long holiday weekend ahead. Here are some quality ways to spend it.

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NASA’s Orion Capsule Passes Launch Abort Test With Flying Colors

The agency confirms that all systems performed perfectly during the second ascent abort test, proving that astronauts aboard Orion could be safely wrenched free of a rocket in the event of an emergency. The post NASA’s Orion Capsule Passes Launch Abort Test With Flying Colors appeared first on ExtremeTech .

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Why Our Postwar “Long Peace” Is Fragile – Facts So Romantic

Have mechanisms like democratization really fostered an enduring trend of peaceful co-existence, or is this just a statistical fluke—a normal interlude of relative calm before another global-scale conflagration? Illustration by Kotenko Oleksandr / Shutterstock You could be forgiven for balking at the idea that our post-World War II reality represents a “Long Peace.” The phrase, given the prevalen

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Intel's New Chip Wizard Has a Plan to Bring Back the Magic

Jim Keller, who joined Intel last year after stints at AMD, Apple, and Tesla, says Moore's law isn't dead, but needs a new, broader interpretation.

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How Extreme Heat Overwhelms Your Body and Becomes Deadly

Europe's record-breaking heat wave serves as a warning of just how dangerous high temperatures can be.

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REI 4th of July Sale: 13 Summer Outdoors Deals for 2019

If you need a water bottle, tent, or a really cool hoodie, it's all on sale at REI's 4th of July Sale on outdoor apparel, accessories, and gear.

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Edmunds weighs pros and cons of in-car personal assistants

In the near future, get ready to do a lot more talking to your car. Smartphone personal assistants, such as Apple's Siri, Amazon's Alexa and Google's Assistant, can be used for a variety of tasks. And thanks to greater availability of the Android Auto and Apple CarPlay smartphone integration systems—just about every new vehicle you shop for in 2019 will offer them—these features can be used in you

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Inhibition of HER2 on tumor cells by molecularly imprinted nanoparticles

A particularly aggressive, metastasizing form of cancer, HER2-positive breast cancer, may be treated with nanoscopic particles "imprinted" with specific binding sites for the receptor molecule HER2. As reported by Chinese researchers in the journal Angewandte Chemie, the selective binding of the nanoparticles to HER2 significantly inhibits multiplication of the tumor cells.

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How common elements can make a more energy-secure future

Thin-film solar panels, the cell phone in your hand and the LED bulb lighting your home are all made using some of the rarest, most expensive elements found on the planet.

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Magnets shown to create more power in electrical generators

Electric generators have a plethora of uses—ranging from automotive to aircraft to microgrids. There is currently a strong desire to reduce the size and increase the efficiency of the devices.

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Picturing access to energy for all in sub-Saharan Africa

The U.N.'s Sustainable Development Goal 7 (SDG 7) aims to ensure access to affordable, reliable, sustainable and modern energy for all populations by 2030. Access to electricity services is, of course, a key priority under this goal, particularly due to the strong interconnections it has with other development objectives. Sub-Saharan Africa remains the region with the largest electricity access de

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Detection of spike-like structures near the front of a shock-driven solar radio burst

Type II solar radio bursts are the result of energetic electrons accelerated by a shock. This kind of burst appears on dynamic spectra as lanes drifting slowly from higher to lower frequencies. Often, scientists observe a fundamental harmonic structure, which sometimes exhibits a division on each band called band split.

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Ethics in the Age of Artificial Intelligence

If we don’t know how AIs make decisions, how can we trust what they decide? — Read more on ScientificAmerican.com

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The highest-energy gamma rays discovered by the Tibet ASgamma experiment

The Tibet ASgamma experiment, a China-Japan joint research project, has discovered the highest energy cosmic gamma rays ever observed from an astrophysical source—in this case, the Crab Nebula. The experiment detected gamma rays ranging from > 100 Teraelectron volts (TeV) (Fig.1) to an estimated 450 TeV. Previously, the highest gamma-ray energy ever observed was 75 TeV by the HEGRA Cherenkov teles

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Brand i formodet russisk spionubåd dræber 14 – intet tegn på radioaktivt udslip

Ifølge russiske medier skete ulykken i den russiske flådes hemmeligste undervandsfartøj – dybvands-miniubåden AS-12 "Losharik".

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Uber Eats Test Lets You Pre-Order Food To Eat In Restaurants

The very reason why many people use Uber Eats is that they don’t feel like going to a restaurant and would rather have the same food in their own home. Uber Eats is conducting a new …

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Solkomfur og larvebøffer: Vilde tiltag skal gøre festival-gæster mere klimavenlige

I år kan gæster på Roskilde Festival blandt andet se, hvor meget CO2 deres festival-mad udleder.

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Understanding what tolerance means in a highly polarized America

The goal of tolerance is not for everyone to arrive at a consensus on divisive issues, or to accept each other's views. Sarah Ruger suggests that tolerance is learning how to coexist peacefully through difference. Tolerance is a word with a lot of baggage, but tolerance is not patronizing or insulting; it is a starting point for something better. Peaceful coexistence and a focus on common goals e

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Rigspolitiet sender aben videre i tele-skandale: Teleselskaber har sendt mangelfulde rådata

Rigspolitiet påpeger en ny fejl i sagen om manglende teleoplysninger, og denne gang skyldes det ikke fejlagtig konvertering i politiets egne it-systemer. Ifølge Politimyndigheden har landets teleselskaber leveret mangelfulde oplysninger om kald via VoLTE og VoWifi.

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Nyt AI-sprog skal gøre kunstig intelligens tilgængeligt for flere

Sproget Gen fra Massachusetts Institute of Technology vil gøre det nemmere for både nybegyndere og eksperter at få resultater med AI.

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A Crime by Any Name

T he horrors detailed in the press were hard to believe. Detainees described overcrowding so severe that “it was difficult to move in any direction without jostling and being jostled.” The water provided them was foul, “of a dark color, and an ordinary glass would collect a thick sediment.” The “authorities never removed any fifth.” A detainee wrote that the “only shelter from the sun and rain an

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A Day of Sorrow for American Democracy

The usual form for a justice who disagrees, no matter how fundamentally, with a decision of the Supreme Court is to end the opinion with the formula “I respectfully dissent.” Justice Antonin Scalia, in particularly high dudgeon, would sometimes drop the adverb. Last week, though, Justice Elena Kagan, writing for the four justices who disagreed with Chief Justice John Roberts’s opinion in Rucho v.

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East Asians may have been reshaping their skulls 12,000 years ago

An ancient skull-molding practice had a long history in northeastern Asia, researchers say.

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The Relentless (and Growing) Problem of Plastic ‘Nurdle’ Pollution

The tiny plastic pellets called nurdles that are the building blocks for most plastic products are lost in production or transit by the millions, washing up on beaches everywhere but posing a special risk to the Gulf Coast of Texas, where currents and a glut of producers conspire to threaten marine life.

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A total solar eclipse just passed over Chile and Argentina

On 2 July, the moon blocked out the sun over areas of Chile and Argentina in the first solar eclipse since the one that passed over the US in 2017

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SESS: School Emergency Safety System

So many schools, churches and businesses lack any security system so I designed this system that uses already available components and technology for dealing with an active shooter or any emergency that requires fast action. ​ SESS: School Emergency Safety System. https://imgur.com/TJU889N ​ 1- All teachers and school personnel have a 2 button wireless remote that can signal school intercom syste

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How natural language can change data visualisation

submitted by /u/UnrealJHXS [link] [comments]

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How a long-distance job move can leave early-career researchers short of cash

Nature, Published online: 03 July 2019; doi:10.1038/d41586-019-02047-z Without reimbursement for relocation costs, PhD students and postdocs are often forced to empty savings accounts, seek financial help or even rack up debt.

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Samsung could end up in French court over ethics pledges: NGOs

Samsung Electronics could end up in the dock in France for not abiding by its own ethics pledges, such as a ban on under-age labour and dangerous working conditions at its factories, two NGOs said on Wednesday.

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Total starts production at French biofuel refinery

Total on Wednesday said it had begun producing biofuel at a refinery in southern France, a project that has sparked an outcry from environmentalists and farmers over its plans to import palm oil.

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Holding Democrats to the Trump Standard

Sometimes it seems like Donald Trump is president in one dimension, and the Democratic-primary race is taking place in another. Democrats are engaged in a back-and-forth over whether the federal government should have superseded local authorities on public-school busing in the 1970s, and over the relative merits of the process as a tool to achieve racial integration. President Trump has offered t

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It's not an antibody, it's a frankenbody: A new tool for live-cell imaging

Researchers from Colorado State University and the Tokyo Institute of Technology have added a new tool to the arsenal of antibody-based probes, but with a powerful distinction: Their genetically encoded probe works in living cells.

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Picturing access to energy for all in sub-Saharan Africa

Satellite images showing nighttime lights on different continents have long been recognized as an indicator of the availability and use of electricity around the world. IIASA researchers examined the precision with which these images can be converted into detailed maps of electricity access in sub-Saharan Africa.

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NIH scientists link genetics to risk of high blood pressure among blacks

Variants in the gene ARMC5 may be associated with high blood pressure among blacks, according to a National Institutes of Health study led by researchers at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The study team identified 17 variants in the ARMC5 gene that were associated with high blood pressure by analyzing genetic research databases that inc

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Marsh harrier 'shot' near Norfolk nature reserve

A wildlife reserve says the future of bird of prey chicks is at risk after one parent is shot.

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Google Pay gets more deeply integrated with Chrome

Google Chrome users will now have an easier way to pay while online shopping, says Google, thanks to an update that lets you access the payment information you’ve saved to your Google …

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VIDEO: Nasas månekapsel bestod sikkerhedstest

Se med fra gårsdagens test af Orion-rumkapslens abortsystem, som skal sikre, at astronauterne overlever, hvis raketten fejler.

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Morphological changes in response to environmental stresses in the fungal plant pathogen Zymoseptoria tritici

Scientific Reports, Published online: 03 July 2019; doi:10.1038/s41598-019-45994-3 Morphological changes in response to environmental stresses in the fungal plant pathogen Zymoseptoria tritici

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Species-Specific Biodegradation of Sporopollenin-Based Microcapsules

Scientific Reports, Published online: 03 July 2019; doi:10.1038/s41598-019-46131-w Species-Specific Biodegradation of Sporopollenin-Based Microcapsules

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The Route to ‘Chemobrain’ – Computational probing of neuronal LTP pathway

Scientific Reports, Published online: 03 July 2019; doi:10.1038/s41598-019-45883-9 The Route to ‘Chemobrain’ – Computational probing of neuronal LTP pathway

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Precipitation Biases in CMIP5 Models over the South Asian Region

Scientific Reports, Published online: 03 July 2019; doi:10.1038/s41598-019-45907-4 Precipitation Biases in CMIP5 Models over the South Asian Region

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Macrophages promote a profibrotic phenotype in orbital fibroblasts through increased hyaluronic acid production and cell contractility

Scientific Reports, Published online: 03 July 2019; doi:10.1038/s41598-019-46075-1 Macrophages promote a profibrotic phenotype in orbital fibroblasts through increased hyaluronic acid production and cell contractility

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Acoustic impact of a wave energy converter in Mediterranean shallow waters

Scientific Reports, Published online: 03 July 2019; doi:10.1038/s41598-019-45926-1 Acoustic impact of a wave energy converter in Mediterranean shallow waters

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FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes

Scientific Reports, Published online: 03 July 2019; doi:10.1038/s41598-019-46110-1 FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes

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Fusion of multiple heterogeneous networks for predicting circRNA-disease associations

Scientific Reports, Published online: 03 July 2019; doi:10.1038/s41598-019-45954-x Fusion of multiple heterogeneous networks for predicting circRNA-disease associations

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Remembering Apollo 11: What to Watch and Listen To

As the 50th anniversary of the moon landing approaches, these movies, television shows and podcasts help shine a light on the story.

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18 millioner kroner til forskning i kunstens samfundsmæssige værdi

På baggrund af en millionbevilling fra Ny Carlsbergfondet etablerer Københavns Universitet…

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It's not an antibody, it's a frankenbody: A new tool for live-cell imaging

Antibodies are the biomolecules our immune systems deploy to find, tag and destroy invading pathogens. They work by binding to specific targets, called epitopes, on the surfaces of antigens—like locks to keys.

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It's not an antibody, it's a frankenbody: A new tool for live-cell imaging

Antibodies are the biomolecules our immune systems deploy to find, tag and destroy invading pathogens. They work by binding to specific targets, called epitopes, on the surfaces of antigens—like locks to keys.

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Remote Mount Michael volcano hosts persistent lava lake

The rare feature exists inside the crater of the Mount Michael stratovolcano in the South Atlantic.

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Terrawatch: how does Old Faithful earn its name?

Scientists are trying to uncover the mystery of the regular geyser’s clockwork-like eruptions Why is Old Faithful so faithful? Roughly every 90 minutes this spectacular geyser in the Yellowstone national park spouts a plume of boiling water 40 metres into the air. In Victorian times people used to put their washing into it, discovering that cotton shirts survived the high-pressure wash, but wooll

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Samband mellan dåliga tänder och personlighet

– Att tänderna är en del av kroppen blir tydligt i studien. Vi kan bland annat se att det verkar finnas ett direkt orsakssamband mellan riskfaktorer för hjärtkärlsjukdom och karies i tänderna, säger Ingegerd Johansson, senior professor vid Odontologiska institutionen vid Umeå universitet och den som lett studien. Karies och tandlossning hör till de allra vanligaste sjukdomarna i hela världen med

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Tesla Model 3 Can Survive a Crash—and Avoid One, Too

The Model 3 scores well in European crash testing, a day after Tesla reported a quarterly record for deliveries.

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US top of the garbage pile in global waste crisis

The US is the world's top producer of waste per head of population, and one of the worst at recycling.

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From a lake high in Madagascar, Africa's own caviar

Madagascar, renowned for its unique wildlife and vanilla production, has a new claim to fame—the island nation is Africa's first and only source of caviar.

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From a lake high in Madagascar, Africa's own caviar

Madagascar, renowned for its unique wildlife and vanilla production, has a new claim to fame—the island nation is Africa's first and only source of caviar.

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Germany is EU's Eldorado for cash machine raiders

"Search for black Audi after attempt to blow up a cash machine", "Neighbours hear loud bang, perpetrators flee in Audi", "Car chase through three federal states": headlines like these have become commonplace around Germany as raids on cash machines have increased in number.

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Automated forklifts elevate firms' profit hopes

A forklift winds its way through the cavernous warehouse in search of a pallet, which it then ferries to a truck, crossing along its way other forklifts and then the driver … oh wait, there is no driver.

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Credit counseling may help reduce consumer debt

By the end of fourth quarter 2018, total household debt in the United States reached a new high of $13.54 trillion. A new Economic Inquiry study found that nonprofit credit counseling—which reaches millions of consumers a year and provides financial education, individualized financial counseling, and debt restructuring services—can be an effective strategy for addressing consumer debt issues.

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US auto industry legend Lee Iacocca dies age 94

Automobile industry legend Lee Iaococca, who is credited with creating the iconic Ford Mustang and saving Chrysler from bankruptcy, died Tuesday at the age of 94, US media reported.

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Tesla's car deliveries rebound, but challenges still abound

Tesla delivered more electric cars in the second quarter than any three-month period in its history, alleviating concerns that demand is waning for its stylish vehicles as tax incentives in its main U.S. market begin to phase out.

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Cockroaches could soon be almost impossible to kill with pesticides

Most common household cockroach able to develop ‘cross resistance’ to multiple types of chemicals, US study finds Cockroaches have become harder to kill and could soon be “almost impossible” to control using pesticides alone, according to a study funded by the United States housing department. Researchers from Purdue University in Indiana spent six months trying to eradicate German cockroaches (

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GeoBits: Lunar Exploration Edition

In this edition, I'll see you on the dark side of the moon — Read more on ScientificAmerican.com

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Nu er der en chip i dit Roskilde-armbånd: »Vi satser på, at folk stoler på, at vi ikke er skurke«

Teknologien er moden til, at Roskilde Festival begynder at indsamle data om publikums bevægemønstre via en NFC-chip i armbåndet, fortæller festivalens it-chef Steen Bechmann Henningsen.

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Greece Is Over Its Crisis, but Europe Isn’t

ATHENS—It has been a problem child, a sick man, a canary in a coal mine, a warning sign, and a long-running experiment into where economics meets politics, with a significant social toll. It has become a rallying cry for Brexiteers and right-wing populists, and has revealed some of the deepest fissures in the European Union. Nearly a decade after it required a bailout in 2010, Greece remains one

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Idioter, røvhuller og dumme kællinger: Vores tone på Facebook bliver grovere

Mere end hver fjerde kommentar er skrevet i et hårdt sprog.

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Country diary: freeloading bumblebees find a shortcut to food

Crook, County Durham: By chewing their way directly into the nectaries of flowers, the thieving insects circumvent the laborious pollination mechanism The first hint that there were thieves in the garden appeared in the columbines. This plant’s common name is derived from the Latin columba , a dove, because its quintet of florets is reminiscent of an inward-facing circle of doves, with petals for

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Credit counseling may help reduce consumer debt

By the end of fourth quarter 2018, total household debt in the United States reached a new high of $13.54 trillion. A new Economic Inquiry study found that nonprofit credit counseling — which reaches millions of consumers a year and provides financial education, individualized financial counseling, and debt restructuring services — can be an effective strategy for addressing consumer debt issues

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Are opioids being inappropriately prescribed to treat gout?

Although there are effective treatments for gout, the most common form of inflammatory arthritis, a new Arthritis Care & Research study found that opioids are commonly prescribed to patients with gout who seek treatment at emergency departments.

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Active sexual life may benefit men with early Parkinson's disease

New research published in the European Journal of Neurology indicates that an active sexual life is linked with lower disability and better quality of life in men with early Parkinson's disease.

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Does marital status affect prognosis after breast cancer diagnosis?

In a Cancer Medicine study of 298,434 patients diagnosed with breast cancer between 2004 and 2012, married patients had a better prognosis than patients who were single, who in turn had a better prognosis than those who were divorced, separated, or widowed.

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Study provides insights into depression in people with inflammatory bowel disease

Depression is common in people with inflammatory bowel disease (IBD), but the actual causes of depression in this group are unknown. In a Neurogastroenterology & Motility study, depression was linked with more severe IBD symptoms, and a less positive cognitive bias in emotional recognition (a reduced ability to recognize basic emotions in others) was involved in this association.

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Pre-eclampsia may carry long-term heart risks for women

Pre-eclampsia is a potentially dangerous condition characterized by high blood pressure that arises in some pregnant women, but a review of published studies in Australasian Journal of Ultrasound in Medicine indicates that its effects on cardiovascular health can persist well after pregnancy.

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Timing of exercise may be key to successful weight loss

In an Obesity study of 375 adults who have successfully maintained weight loss and who engage in moderate-to-vigorous intensity physical activity, most reported consistency in the time of day that they exercised, with early morning being the most common time.

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Depression is common and linked with early death in patients with blood cancers

In a Psycho-Oncology study of patients newly diagnosed with lymphoma or multiple myeloma, one-third of participants reported depressive symptoms around the time of diagnosis, and depressive symptoms were linked with shorter survival.

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Respiratory symptoms predict life expectancy in older adults

New research published in Respirology suggests that some respiratory symptoms may predict an earlier death in older adults. Also, such predictions differ by smoking status.

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Medication linked to increased risk of inflammatory bowel disease

Medications that target tumor necrosis factor alpha (TNFα), a protein involved in inflammation, have revolutionized the management of certain autoimmune diseases, but paradoxically, these agents might provoke the development of other autoimmune conditions.

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The global prevalence of erectile dysfunction

A review of published studies found that estimates for the global prevalence of erectile dysfunction vary widely, ranging from 3% to 76.5%. The findings are published in BJU International.

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Diet quality may affect risk of frailty in older adults

Poorer overall diet quality was linked with an increased risk of becoming frail in a study of US community-dwelling older adults, published in the Journal of the American Geriatrics Society.

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HIV infection may increase heart failure and stroke risk

A Journal of the American Heart Association analysis of information from a large health insurance database reveals that people living with HIV have an elevated risk of developing cardiovascular disease (CVD), particularly heart failure and stroke.

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Adults with type 2 diabetes face high risk of dying from cancer

Cancer has overtaken cardiovascular disease as the most common cause of death in Scottish adults with type 2 diabetes, according to a study published in the Journal of Diabetes Investigation.

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How to sell labriculture: Less lab, more culture

In the near future, we will be able to mass-produce meat directly from animal cells.This cultured meat could change the world — or it could falter like GM 'frankenfoods.'Writing in Frontiers in Nutrition, researchers warn that the most common media framing of cultured meat — as a 'high-tech' innovation — may be the least effective in garnering consumer acceptance.

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Thousands watch total solar eclipse from Chile and Argentina – in pictures

Thousands gathered across Chile and Argentina to witness the only total solar eclipse for 2019. Northern Chile is known for clear skies and is being turned into a global astronomy hub ‘Something supreme’: thousands in Chile and Argentina marvel at total solar eclipse Continue reading…

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The highest energy gamma rays discovered by the Tibet ASgamma experiment

The Tibet ASgamma experiment, a China-Japan joint research project, has discovered the highest energy cosmic gamma rays ever observed from an astrophysical source – in this case, the 'Crab Nebula.' The experiment detected gamma rays ranging from > 100 Teraelectron volts (TeV) to an estimated 450 TeV.

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DNA from tooth in Florida man's foot solves 25-year-old shark bite mystery

When Jeff Weakley tweezed open a blister-like bulge on his foot, he was not expecting to find a piece of tooth from a shark that bit him while he was surfing off Flagler Beach in 1994.

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Loftet styrtede ned på rådhus: Skruer monteret forkert

PLUS. I december styrtede et nedhængt loft ned over borgere og ansatte på Hvidovre Rådhus. Entreprenøren, der arbejdede på bygningens tag, er nu blevet frikendt.

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The winning formula behind Silicon Fen’s success story

Collaboration between academics and entrepreneurs over 30 years transforms region

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Photos Capture the Great South American Eclipse

On July 2, residents of Chile and Argentina witnessed the first total solar eclipse since August 2017

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Superhydrophobic 'nanoflower' for biomedical applications

Plant leaves have a natural superpower — they're designed with water repelling characteristics. Called a superhydrophobic surface, this trait allows leaves to cleanse themselves from dust particles. Inspired by such natural designs, a team of researchers at Texas A&M University has developed an innovative way to control the hydrophobicity of a surface to benefit to the biomedical field.

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Gene editing could help eliminate HIV

In a new study, researchers combined the CRISPR gene editing technique with an enhanced version of the virus-suppressing drugs normally given to treat HIV, shown above, and were able to eliminate the virus entirely in animal models. (Wikimedia Commons/) Around five years ago, when the gene editing technology CRISPR was still new, Kamel Khalili started work on ways to use the system to treat and c

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PHOTOS: Solar Eclipse Shrouds Parts Of South America In Temporary Darkness

Chile and Argentina got their turn to host a total solar eclipse. People brought out special glasses, and even protective suits, to watch the celestial event. (Image credit: Martin Bernetti/AFP/Getty Images)

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Neural nets to simulate molecular motion cast

New work is showing that artificial neural nets can be trained to encode quantum mechanical laws to describe the motions of molecules, supercharging simulations potentially across a broad range of fields.

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Tesla Pickup Truck Generates More Buzz Than Ford F-150

submitted by /u/The_Write_Stuff [link] [comments]

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In a future where a handful of companies control robots how do we control the companies?

Watching a movie called "next gen" with my kids on Netflix and it makes me wonder. In a future where robotics companies are so involved in day to day life there would inevitably be one or two companies that rise to the top. Think apple and Android. If they control the robots instead of the government how would we prevent the companies from having more control than the government? submitted by /u/

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Superhydrophobic 'nanoflower' for biomedical applications

Plant leaves have a natural superpower — they're designed with water repelling characteristics. Called a superhydrophobic surface, this trait allows leaves to cleanse themselves from dust particles. Inspired by such natural designs, a team of researchers at Texas A&M University has developed an innovative way to control the hydrophobicity of a surface to benefit to the biomedical field.

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Tiny supersonic jet injector accelerates nanoscale additive manufacturing

By energizing precursor molecules using a tiny, high-energy supersonic jet of inert gas, researchers have dramatically accelerated the fabrication of nanometer scale structures. The rapid additive manufacturing technique also allows them to produce structures with high aspect ratios. Now, a theory developed to describe the technique could lead to new applications for additive nanomanufacturing and

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Sister, neighbor, friend: Thinking about multiple roles boosts kids' performance

A typical child plays many roles, such as friend, neighbor, son or daughter. Simply reminding children of that fact can lead to better problem-solving and more flexible thinking, finds new research. Better problem-solving was just one positive finding of the study. After considering their own various identities, children also showed more flexible thinking about race and other social groupings — a

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Neural nets to simulate molecular motion cast

New work is showing that artificial neural nets can be trained to encode quantum mechanical laws to describe the motions of molecules, supercharging simulations potentially across a broad range of fields.

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Unforced variations: July 2019

This month’s open thread for climate science discussions.

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Lawsuit Accuses Android Co-Founder Andy Rubin of Hiding Wealth From Wife, Running 'Sex Ring'

Court documents from a civil complaint brought by disgraced former Google executive Andy Rubin’s estranged spouse, Rie Hirabaru Rubin, and obtained by BuzzFeed News, claim that Rubin left Google …

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A short bout of exercise enhances brain function

Neuroscientists, working with mice, have discovered that a short burst of exercise directly boosts the function of a gene that increases connections between neurons in the hippocampus, the region of the brain associated with learning and memory.

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Using artificial intelligence to better predict severe weather

When forecasting weather, meteorologists use a number of models and data sources to track shapes and movements of clouds that could indicate severe storms. However, with increasingly expanding weather data sets and looming deadlines, it is nearly impossible for them to monitor all storm formations — especially smaller-scale ones — in real time.

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Combat veterans more likely to experience mental health issues in later life

Military veterans exposed to combat were more likely to exhibit signs of depression and anxiety in later life than veterans who had not seen combat, a new study shows.

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Tiny granules can help bring clean and abundant fusion power to Earth

Physicists have concluded that injecting tiny beryllium pellets into ITER could help stabilize the plasma that fuels fusion reactions.

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Nanoscale pendulum coupling

In 1665, Lord Christiaan Huygens found that two pendulum clocks, hung in the same wooden structure, oscillated spontaneously and perfectly in line but in opposite directions: the clocks oscillated in anti-phase. A new article showed a nanoscale version of mechanical oscillators.

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New stillbirth risk figures help women's decisions on timing delivery

Researchers say that women who are 41 weeks pregnant should not be alarmed, as the increased risk is low — equivalent to one additional stillbirth for every 1,449 pregnancies, compared to delivering at 40 weeks.

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A NEAT discovery about memory

Researchers say over expression of NEAT1, an noncoding RNA, appears to diminish the ability of older brains to form memories. Inhibiting NEAT1 via CRISPR technology could be a means to improve memory in older humans.

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Solitude breeds aggression in spiders (rather than vice versa)

Spiders start out social but later turn aggressive after dispersing and becoming solitary, according to a new study.

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Total solar eclipse: thousands in Chile and Argentina marvel at 'something supreme'

Best views were in the Atacama desert, where a total eclipse has not occurred since 1592 • Thousands watch total solar eclipse from Chile and Argentina – in pictures Hundreds of thousands of tourists scattered across the north Chilean desert on Tuesday to experience a rare and irresistible combination for astronomy buffs: a total eclipse of the sun viewed from beneath the world’s clearest skies.

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Pesticide exposure linked to teen depression

Adolescent depression increases with exposure to pesticides, a study in the Ecuadorian Andes shows.

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Proteins trapped in glass could yield new medicinal advances

Researchers have developed a unique method for studying proteins which could open new doors for medicinal research. Through capturing proteins in a nano-capsule made of glass, the researchers have been able to create a unique model of proteins in natural environments.

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Brain injury common in domestic violence

Domestic violence survivors commonly suffer repeated blows to the head and strangulation, trauma that has lasting effects that should be widely recognized by advocates, health care providers, law enforcement and others who are in a position to help, according to the authors of a new study.

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Personalized medicine software vulnerability uncovered

A weakness in one common open source software for genomic analysis left DNA-based medical diagnostics vulnerable to cyberattacks. Researchers identified the weakness and notified the software developers, who issued a patch to fix the problem. The issue has also been fixed in the latest release of the software, and no attack from this vulnerability is known.

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Why some cities turn off the water pipes at night

For more than a billion people around the world, running water comes from water systems that turn on and off at certain times. A new article proposes a model to explain why and how these systems come to be — and how they fit into meeting international targets for human development and safe drinking water.

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Obese people outnumber smokers two to one

New figures from Cancer Research UK show that people who are obese now outnumber people who smoke two to one in the UK, and excess weight causes more cases of certain cancers than smoking, as the charity urges government action to tackle obesity.

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Megan Rapinoe Is a Patriot

Two days before President Donald Trump commandeers the Mall to stage his grotesque celebration of American nationhood, the U.S. women’s national soccer team replicated the results of the original revolution, with a savvy and willful defeat of England. It’s important to pause and contrast these two events: Trump’s efforts to rebrand the Fourth of July and the women earning a place in the World Cup

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With BrainNet, 3 people play Tetris with their minds

A new system called BrainNet lets three people play a Tetris-like game using a brain-to-brain interface. This is the first demonstration of two things: a brain-to-brain network of more than two people, and a person being able to both receive and send information to others using only their brain. “Humans are social beings who communicate with each other to cooperate and solve problems that none of

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Photos From the 2019 Solar Eclipse in Chile and Argentina

Photographers and astronomers were strung out across the Atacama Desert waiting for the sun to spread its coronal wings on their examining table.

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Vandals, angry artists, and mustachioed tinkerers: The story of New York City’s weather forecasting castle

The Belvedere in New York's Central Park. (hjjanish via Flickr/) When Central Park's master planners Frederick Law Olmsted and Calvert Vaux drew up the initial design for the Belvedere in the 1860s, their real focus was on the scenery. Belvedere, in Italian, means "fair view," and it was. The rocky little castle, part granite and part Manhattan schist, was a folly; a decoration instead of a build

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Face quirks unmask deepfake videos

A new approach to fighting deepfake videos uses the subtle characteristics of how a person speaks, such as former President Barack Obama’s distinct head nods and lip purses. After watching hours of video footage of Obama delivering his weekly address, Shruti Agarwal began to notice a few quirks about the way Obama speaks. “Every time he says ‘Hi, everybody,’ he moves his head up to the left or th

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It’s now easier to study a dangerous parasite

Researchers have figured out how to grow the most common type of the parasite Cryptosporidium in the lab. Cryptosporidium is one of the most common causes of diarrhea worldwide. It accounts for millions of cases and tens of thousands of deaths, mostly of small children. Doctors can treat children with Cryptosporidium for dehydration, but unlike many other causes of diarrhea, there are no drugs to

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Is wildfire management 'for the birds?'

Spotted owl populations are in decline all along the West Coast, and as climate change increases the risk of large and destructive wildfires in the region, these iconic animals face the real threat of losing even more of their forest habitat. Wildfire management — through prescribed burning and restoration thinning — could help save the species, argues a new article.

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Unraveling the brain's reward circuits

Food, alcohol, and certain drugs all act to reduce the activity of hunger neurons and to release reward signals in the brain, but alcohol and drugs rely on a different pathway than does food, according to a new study. The findings could point researchers to new strategies to design weight-loss or anti-addiction drugs.

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Tiny motor can 'walk' to carry out tasks

Researchers have assembled microrobots from a small set of standardized components, as a step toward self-replicating systems.

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Promising approach: Prevent diabetes with intermittent fasting

Intermittent fasting is known to improve sensitivity to the blood glucose-lowering hormone insulin and to protect against fatty liver. Scientists have now discovered that mice on an intermittent fasting regimen also exhibited lower pancreatic fat.The researchers showed the mechanism by which pancreatic fat could contribute to the development of type 2 diabetes.

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The way sickle cells form may be key to stopping them

Chemists are reporting a new finding on how sickle cells are formed, which may lead not only to stopping their formation, but to new avenues for making uniformly-sized nanoparticles for industry.

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DNA from tooth in Florida man's foot solves 25-year-old shark bite mystery

In 2018, a Florida man found a piece of tooth embedded in his foot from a shark bite off Flagler Beach 24 years earlier. A DNA test of the tooth revealed the kind of shark that had nabbed his foot nearly a quarter century ago: a blacktip.

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Airless worms: A new hope against drug-resistant parasites

Scientists have uncovered a metabolic pathway that only exists in parasitic worms. This will allow development of drugs that target parasites only without harming the human host.

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Bench to bedside study of a targetable enzyme controlling aggressive prostate cancer

Prostate cancer represents a major health challenge and there is currently no effective treatment once it has advanced to the aggressive, metastatic stage. A new has revealed a key cellular mechanism that contributes to aggressive prostate cancer, and supporting a new clinical trial.

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Using facts to promote cancer prevention on social media is more effective than anecdotes

Clear information from trusted organizations has greater reach on social media than personal accounts.

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Innate immune responses to high-fat diets lead to obesity

Why is eating a high fat diet a recipe for obesity? According to a new study, the answer involves the activity of a specific type of immune cell that lives in the small intestine. Experiments showed that without group-2 innate lymphoid cells (ILC2s) in the small intestines, mice can eat high-fat diets without gaining extra weight or suffering from other physiological symptoms of obesity.

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Integrated, multi-'omic' studies of asthma could lead to precision treatment

Carefully designed, integrated multi-'omic' studies could accelerate the use of precision medicine for asthma patients, according to researchers.

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HIV eliminated from the genomes of living animals

Researchers have for the first time eliminated replication-competent HIV-1 DNA — the virus responsible for AIDS — from the genomes of living animals. The study marks a critical step toward the development of a possible cure for human HIV infection.

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Antidepressants reduce deaths by more than a third in patients with diabetes

Antidepressants reduce deaths by more than a third in patients with diabetes and depression, according to a new study.

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Black hole brings down curtain on jellyfish galaxy's star turn

The role of an excited black hole in the death of an exotic 'jellyfish' galaxy will be presented today (July 3) by Callum Bellhouse of the University of Birmingham at the RAS National Astronomy Meeting in Lancaster. The supermassive black hole at the center of jellyfish galaxy JO201 is stripping away gas and throwing it out into space, accelerating suppression of star formation and effectively 'ki

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It's dog eat dog on the canine social ladder

Climbing the social ladder is a ruff business for dogs, new research shows.

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Details of UK-led solar science mission revealed at National Astronomy Meeting

Details of a UK-led solar science mission designed to to answer fundamental questions about the physics of solar storms will be presented at the RAS National Astronomy Meeting on Wednesday, July 3. The mission will also demonstrate the use of laser power transfer in space and laser communications in Low Earth Orbits (i.e. for both inter-satellite communications and satellite-to-Earth communication

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Unraveling the complexity of oxygen reactions on Pt surfaces [Commentaries]

Platinum (Pt) is a key material in automotive catalytic converters used to clean up the exhaust of the combustion engine. Pt particles in a ceramic matrix serve as an oxidation catalyst to eliminate toxic carbon monoxide (CO) and unburned hydrocarbons (CxHy) from the engine’s exhaust gases. For this process to…

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Selective targeting of PARP-2 inhibits androgen receptor signaling and prostate cancer growth through disruption of FOXA1 function [Biochemistry]

Androgen receptor (AR) is a ligand-activated transcription factor and a key driver of prostate cancer (PCa) growth and progression. Understanding the factors influencing AR-mediated gene expression provides new opportunities for therapeutic intervention. Poly(ADP-ribose) Polymerase (PARP) is a family of enzymes, which posttranslationally modify a range of proteins and regulate many…

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p110{gamma} deficiency protects against pancreatic carcinogenesis yet predisposes to diet-induced hepatotoxicity [Medical Sciences]

Pancreatic ductal adenocarcinoma (PDAC) is notorious for its poor survival and resistance to conventional therapies. PI3K signaling is implicated in both disease initiation and progression, and specific inhibitors of selected PI3K p110 isoforms for managing solid tumors are emerging. We demonstrate that increased activation of PI3K signals cooperates with oncogenic…

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Supermolecules steer electrons down a wrong-way street [Commentaries]

The controlled movement of electrons is of paramount importance for solving current technological problems that will have broad societal impact. Batteries for electric vehicles, quantum computers, efficient solar energy conversion devices, and nanoscale machines for biomedical applications represent just a handful of such possible advances. A current research thrust is…

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Strong quantum fluctuations in a quantum spin liquid candidate with a Co-based triangular lattice [Physics]

Currently under active study in condensed matter physics, both theoretically and experimentally, are quantum spin liquid (QSL) states, in which no long-range magnetic ordering appears at low temperatures due to strong quantum fluctuations of the magnetic moments. The existing QSL candidates all have their intrinsic disadvantages, however, and solid evidence…

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Motile curved bacteria are Pareto-optimal [Biophysics and Computational Biology]

Curved rods are a ubiquitous bacterial phenotype, but the fundamental question of why they are shaped this way remains unanswered. Through in silico experiments, we assessed freely swimming straight- and curved-rod bacteria of a wide diversity of equal-volume shapes parameterized by elongation and curvature, and predicted their performances in tasks…

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High-frequency microrheology in 3D reveals mismatch between cytoskeletal and extracellular matrix mechanics [Biophysics and Computational Biology]

Mechanical homeostasis describes how cells sense physical cues from the microenvironment and concomitantly remodel both the cytoskeleton and the surrounding extracellular matrix (ECM). Such feedback is thought to be essential to healthy development and maintenance of tissue. However, the nature of the dynamic coupling between microscale cell and ECM mechanics…

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Visualization of an axion insulating state at the transition between 2 chiral quantum anomalous Hall states [Physics]

Quantum-relativistic materials often host electronic phenomena with exotic spatial distributions. In particular, quantum anomalous Hall (QAH) insulators feature topological boundary currents whose chirality is determined by the magnetization orientation. However, understanding the microscopic nature of edge vs. bulk currents has remained a challenge due to the emergence of multidomain states…

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Disentangling lattice and electronic contributions to the metal-insulator transition from bulk vs. layer confined RNiO3 [Applied Physical Sciences]

In complex oxide materials, changes in electronic properties are often associated with changes in crystal structure, raising the question of the relative roles of the electronic and lattice effects in driving the metal–insulator transition. This paper presents a combined theoretical and experimental analysis of the dependence of the metal–insulator transition…

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Two modes of cis-activation of switch transcription by the IgH superenhancer [Immunology and Inflammation]

B cell isotype switching plays an important role in modulating adaptive immune responses. It occurs in response to specific signals that often induce different isotype (I) promoters driving transcription of switch regions, located upstream of the Ig heavy chain (IgH) constant genes. The transcribed switch regions can recombine, leading to…

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Insula serotonin 2A receptor binding and gene expression contribute to serotonin transporter polymorphism anxious phenotype in primates [Neuroscience]

Genetic variation in the serotonin transporter gene (SLC6A4) is associated with vulnerability to affective disorders and pharmacotherapy efficacy. We recently identified sequence polymorphisms in the common marmoset SLC6A4 repeat region (AC/C/G and CT/T/C) associated with individual differences in anxiety-like trait, gene expression, and response to antidepressants. The mechanisms underlying the..

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Meiotic viral attenuation through an ancestral apoptotic pathway [Genetics]

The programmed release of apoptogenic proteins from mitochondria is a core event of apoptosis, although ancestral roles of this phenomenon are not known. In mammals, one such apoptogenic protein is Endonuclease G (EndoG), a conserved mitochondrial nuclease that fragments the DNA of dying cells. In this work, we show that…

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Pandemic fluoroquinolone resistant Escherichia coli clone ST1193 emerged via simultaneous homologous recombinations in 11 gene loci [Microbiology]

Global growth in antibiotic resistance is a major social problem. A high level of resistance to fluoroquinolones requires the concurrent presence of at least 3 mutations in the target proteins—2 in DNA gyrase (GyrA) and 1 in topoisomerase IV (ParC), which occur in a stepwise manner. In the Escherichia coli…

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An unbiased approach elucidates variation in (S)-(+)-linalool, a context-specific mediator of a tri-trophic interaction in wild tobacco [Ecology]

Plant volatile organic compounds (VOCs) mediate many interactions, and the function of common VOCs is especially likely to depend on ecological context. We used a genetic mapping population of wild tobacco, Nicotiana attenuata, originating from a cross of 2 natural accessions from Arizona and Utah, separated by the Grand Canyon,…

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A modern maximum-likelihood theory for high-dimensional logistic regression [Statistics]

Students in statistics or data science usually learn early on that when the sample size n is large relative to the number of variables p, fitting a logistic model by the method of maximum likelihood produces estimates that are consistent and that there are well-known formulas that quantify the variability…

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Characterizing round spheres using half-geodesics [Mathematics]

A half-geodesic is a closed geodesic realizing the distance between any pair of its points. All geodesics in a round sphere are half-geodesics. Conversely, this paper establishes that Riemannian spheres with all geodesics closed and sufficiently many half-geodesics are round.

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Replication fork stalling elicits chromatin compaction for the stability of stalling replication forks [Biochemistry]

DNA replication forks in eukaryotic cells stall at a variety of replication barriers. Stalling forks require strict cellular regulations to prevent fork collapse. However, the mechanism underlying these cellular regulations is poorly understood. In this study, a cellular mechanism was uncovered that regulates chromatin structures to stabilize stalling forks. When…

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Redox control on nitrogen isotope fractionation during planetary core formation [Earth, Atmospheric, and Planetary Sciences]

The present-day nitrogen isotopic compositions of Earth’s surficial (15N-enriched) and deep reservoirs (15N-depleted) differ significantly. This distribution can neither be explained by modern mantle degassing nor recycling via subduction zones. As the effect of planetary differentiation on the behavior of N isotopes is poorly understood, we experimentally determined N-isotopic fractionations…

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Diversification of small RNA amplification mechanisms for targeting transposon-related sequences in ciliates [Developmental Biology]

The silencing of repetitive transposable elements (TEs) is ensured by signal amplification of the initial small RNA trigger, which occurs at distinct steps of TE silencing in different eukaryotes. How such a variety of secondary small RNA biogenesis mechanisms has evolved has not been thoroughly elucidated. Ciliated protozoa perform small…

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Global mitigation potential of carbon stored in harvested wood products [Sustainability Science]

Carbon stored in harvested wood products (HWPs) can affect national greenhouse gas (GHG) inventories, in which the production and end use of HWPs play a key role. The Intergovernmental Panel on Climate Change (IPCC) provides guidance on HWP carbon accounting, which is sensitive to future developments of socioeconomic factors including…

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Mapping the native organization of the yeast nuclear pore complex using nuclear radial intensity measurements [Cell Biology]

Selective transport across the nuclear envelope (NE) is mediated by the nuclear pore complex (NPC), a massive ∼100-MDa assembly composed of multiple copies of ∼30 nuclear pore proteins (Nups). Recent advances have shed light on the composition and structure of NPCs, but approaches that could map their organization in live…

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Wind farm power optimization through wake steering [Engineering]

Global power production increasingly relies on wind farms to supply low-carbon energy. The recent Intergovernmental Panel on Climate Change (IPCC) Special Report predicted that renewable energy production must leap from 20% of the global energy mix in 2018 to 67% by 2050 to keep global temperatures from rising 1.5°C above…

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Long noncoding RNA EMS connects c-Myc to cell cycle control and tumorigenesis [Cell Biology]

Deregulated expression of c-Myc is an important molecular hallmark of cancer. The oncogenic function of c-Myc has been largely attributed to its intrinsic nature as a master transcription factor. Here, we report the long noncoding RNA (lncRNA) E2F1 messenger RNA (mRNA) stabilizing factor (EMS) as a direct c-Myc transcriptional target….

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Ecomorphological diversification in squamates from conserved pattern of cranial integration [Evolution]

Factors intrinsic and extrinsic to organisms dictate the course of morphological evolution but are seldom considered together in comparative analyses. Among vertebrates, squamates (lizards and snakes) exhibit remarkable morphological and developmental variations that parallel their incredible ecological spectrum. However, this exceptional diversity also makes systematic quantification and analysis

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Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen [Immunology and Inflammation]

Conventional dendritic cells (cDCs) derive from bone marrow (BM) precursors that undergo cascades of developmental programs to terminally differentiate in peripheral tissues. Pre-cDC1s and pre-cDC2s commit in the BM to each differentiate into CD8α+/CD103+ cDC1s and CD11b+ cDC2s, respectively. Although both cDCs rely on the cytokine FLT3L during development, mechanisms…

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Correction for Davis, Profile of Aravinda Chakravarti [Corrections]

PROFILE Correction for “Profile of Aravinda Chakravarti,” by Tinsley H. Davis, which was first published May 6, 2019; 10.1073/pnas.1906109116 (Proc. Natl. Acad. Sci. U.S.A. 116, 10608–10610). The editors wish to note that on page 10609, Dr. C. C. Li was described as a founder of the field of population genetics….

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A 40-y record reveals gradual Antarctic sea ice increases followed by decreases at rates far exceeding the rates seen in the Arctic [Environmental Sciences]

Following over 3 decades of gradual but uneven increases in sea ice coverage, the yearly average Antarctic sea ice extents reached a record high of 12.8 × 106 km2 in 2014, followed by a decline so precipitous that they reached their lowest value in the 40-y 1979–2018 satellite multichannel passive-microwave…

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Neural adaptation to faces reveals racial outgroup homogeneity effects in early perception [Psychological and Cognitive Sciences]

A hallmark of intergroup biases is the tendency to individuate members of one’s own group but process members of other groups categorically. While the consequences of these biases for stereotyping and discrimination are well-documented, their early perceptual underpinnings remain less understood. Here, we investigated the neural mechanisms of this effect…

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Female bed bugs (Cimex lectularius L) anticipate the immunological consequences of traumatic insemination via feeding cues [Evolution]

Not all encounters with pathogens are stochastic and insects can adjust their immune management in relation to cues associated with the likelihood of infection within a life cycle as well as across generations. In this study we show that female insects (bed bugs) up-regulate immune function in their copulatory organ…

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Bovine tuberculosis disturbs parasite functional trait composition in African buffalo [Ecology]

Novel parasites can have wide-ranging impacts, not only on host populations, but also on the resident parasite community. Historically, impacts of novel parasites have been assessed by examining pairwise interactions between parasite species. However, parasite communities are complex networks of interacting species. Here we used multivariate taxonomic and trait-based approaches…

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De novo design of symmetric ferredoxins that shuttle electrons in vivo [Biochemistry]

A symmetric origin for bacterial ferredoxins was first proposed over 50 y ago, yet, to date, no functional symmetric molecule has been constructed. It is hypothesized that extant proteins have drifted from their symmetric roots via gene duplication followed by mutations. Phylogenetic analyses of extant ferredoxins support the independent evolution…

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Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells [Cell Biology]

Aberrant MYC oncogene activation is one of the most prevalent characteristics of cancer. By overlapping datasets of Drosophila genes that are insulin-responsive and also regulate nucleolus size, we enriched for Myc target genes required for cellular biosynthesis. Among these, we identified the aminoacyl tRNA synthetases (aaRSs) as essential mediators of…

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Epistasis between antibiotic tolerance, persistence, and resistance mutations [Microbiology]

Understanding the evolution of microorganisms under antibiotic treatments is a burning issue. Typically, several resistance mutations can accumulate under antibiotic treatment, and the way in which resistance mutations interact, i.e., epistasis, has been extensively studied. We recently showed that the evolution of antibiotic resistance in Escherichia coli is facilitated by…

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AAV2/9-mediated overexpression of MIF inhibits SOD1 misfolding, delays disease onset, and extends survival in mouse models of ALS [Neuroscience]

Mutations in superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by the loss of upper and lower motor neurons. Transgenic mice that overexpress mutant SOD1 develop paralysis and accumulate misfolded SOD1 onto the cytoplasmic faces of intracellular organelles, including mitochondria and endoplasmic reticulum (ER). Recently, macrophage…

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Quantifying the transmission dynamics of MRSA in the community and healthcare settings in a low-prevalence country [Biophysics and Computational Biology]

Methicillin-resistant Staphylococcus aureus (MRSA) is a primarily nosocomial pathogen that, in recent years, has increasingly spread to the general population. The rising prevalence of MRSA in the community implies more frequent introductions in healthcare settings that could jeopardize the effectiveness of infection-control procedures. To investigate the epidemiological dynamics of MRSA…

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Ambidextrous helical nanotubes from self-assembly of designed helical hairpin motifs [Chemistry]

Tandem repeat proteins exhibit native designability and represent potentially useful scaffolds for the construction of synthetic biomimetic assemblies. We have designed 2 synthetic peptides, HEAT_R1 and LRV_M3Δ1, based on the consensus sequences of single repeats of thermophilic HEAT (PBS_HEAT) and Leucine-Rich Variant (LRV) structural motifs, respectively. Self-assembly of the peptides…

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Gas phase formation of c-SiC3 molecules in the circumstellar envelope of carbon stars [Chemistry]

Complex organosilicon molecules are ubiquitous in the circumstellar envelope of the asymptotic giant branch (AGB) star IRC+10216, but their formation mechanisms have remained largely elusive until now. These processes are of fundamental importance in initiating a chain of chemical reactions leading eventually to the formation of organosilicon molecules—among them key…

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Photos Capture the Great South American Eclipse

On July 2, residents of Chile and Argentina witnessed the first total solar eclipse since August 2017

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Doctors not prescribing medicinal cannabis due to lack of clinical trials

Commons’ health committee warns patients’ expectations are being disappointed High expectations among the public of the benefits of medicinal cannabis are being disappointed because doctors are unwilling to prescribe it in the knowledge that there is little evidence to stand up some of the claims, according to MPs. A House of Commons health select committee inquiry says the hopes of patients and

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This strategy may be best to save corals from climate change

Conserving a wide range of habitats is the best way to protect the corals that climate change threatens, according to a new study. The finding likely applies to conservation efforts for many other species in the ocean and on land, including trees and birds. “Rather than conserving just the cold places with corals, we found that the best strategies will conserve a wide diversity of sites,” says co

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Trendy on eight legs: Jumping spider named after fashion czar Karl Lagerfeld

New to science species of Australian jumping spider was named after Hamburg-born fashion icon Karl Lagerfeld (1933-2019) after the arachnid reminded its discoverers of the designer. Intrigued by the distinct 'downplayed' black-and-white colors of the arachnid, the team likened its appearance to the trademark style of the German designer.

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Antibiotics weaken flu defenses in the lung

Antibiotics can leave the lung vulnerable to flu viruses, leading to significantly worse infections and symptoms, finds a new study. The research discovered that signals from gut bacteria help to maintain a first line of defense in the lining of the lung. When mice with healthy gut bacteria were infected with the flu, around 80% of them survived. However, only a third survived if they were given a

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Dramatic differences in tests assessing preschoolers' language skills

Researchers examined the impact of preterm birth on language outcomes in preschoolers born preterm and full-term, using both standardized assessment and language sample analysis. They also explored semantic skills and grammatical ability, and nonlinguistic developmental skills of nonverbal intelligence, attention, and hyperactivity. Results show that language difficulties at the discourse level ma

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What do sick kids really want in hospital?

Researchers developed the 'Needs of Children Questionnaire' (NCQ), the first of its kind to measure children's self-reported psychosocial, physical and emotional needs in pediatric wards.

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Plasma in space isn’t as viscous as we thought

By examining the plasma in a distant galaxy cluster, researchers have discovered that the flow of plasma is much less viscous than expected. Therefore, they say, turbulence occurs on relatively small scales. The research provides a brand-new glimpse of the small-scale physics of plasma. The findings could be important for numerical models of the largest objects in the universe. Most visible matte

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My nine steps to success as a PhD student in Nigeria

Nature, Published online: 02 July 2019; doi:10.1038/d41586-019-02072-y Medical physicist Iyobosa Uwadiae ignored sceptics who questioned her plan to pursue a doctoral programme in the African nation. Here is her advice.

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Synthesizing chemical-sensing cells from scratch

Scientists create artificial cells that can express distinct genes in response to specific chemical signals, opening the door to new ways of delivering drugs.

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Bentley's New Hybrid Hides Its Luxury From the Masses

The Bentley Bentayga Hybrid can go from 0 to 60 mph in 5.2 seconds and deliver more than 500 pound-feet of torque. And the windshield wipers are hidden.

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Black hole brings down curtain on jellyfish galaxy's star turn

The role of an excited black hole in the death of an exotic 'jellyfish' galaxy will be presented today (3 July) by Callum Bellhouse of the University of Birmingham at the RAS National Astronomy Meeting in Lancaster. The supermassive black hole at the centre of jellyfish galaxy JO201 is stripping away gas and throwing it out into space, accelerating suppression of star formation and effectively 'ki

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Details of UK-led solar science mission revealed

Named after a Celtic goddess of the Sun, SULIS is a UK-led solar science mission, designed to answer fundamental questions about the physics of solar storms. The mission consists of a cluster of small satellites and will carefully monitor solar storms using state-of-the-art UK technology, as well as demonstrating new technologies in space. Lead Investigator on the project, Dr. Eamon Scullion of No

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It's dog eat dog on the canine social ladder

Climbing the social ladder is a ruff business for dogs, new research shows.

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It's dog eat dog on the canine social ladder

Climbing the social ladder is a ruff business for dogs, new research shows.

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Noah Schnapp of 'Stranger Things' Has a Crush on Zendaya

Get in line behind Spider-Man, friend.

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Second Non-Repeating Fast Radio Burst Tracked to Its Source

The Deep Synoptic Array-10, which spotted the burst, is located at the Owens Valley Radio Observatory. (Credit: Caltech/OVRO/Gregg Hallinan) Fast radio bursts, or FRBs, are one of astronomy’s hottest topics — and biggest mysteries. These brief bursts of radio waves from outside the Milky Way typically pop off for only a fraction of a second, then disappear forever, never to be seen again. Only two

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Few US higher education campuses have gone completely smoke and/or tobacco-free

Just one in six accredited US colleges and universities have gone completely smoke and/or tobacco free, reveals the first study of its kind, published in the journal Tobacco Control.

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Proliferation of JUUL-related content on Instagram likely to appeal to the young

There has been a proliferation of JUUL-related content on the photo and video sharing social media service, Instagram, that is likely to appeal to young people, reveals research published online in the journal Tobacco Control.

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Made in Space: Why Earth's Industries Might One Day Leave Our Planet

Asteroids like Psyche 16, thought to be the core of a vanished planet, could be worth trillions. (Credit: Maxar/ASU/P. Rubin/NASA/JPL-Caltech) What if the key to protecting our planet … was leaving it? Well, in part, at least. As worries about climate change mount, and the race to obtain resources from space heats up, some experts and über-rich CEOs are seriously considering moving our industry of

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Synthesizing chemical-sensing cells from scratch

Scientists create artificial cells that can express distinct genes in response to specific chemical signals, opening the door to new ways of delivering drugs.

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Brain imaging may help identify teens at risk of increasing alcohol use

Teenagers with large amounts of grey matter in the brain at age 14 are more likely to increase their alcohol use over the next five years, according to a whole brain imaging study.

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Equations help predict the behavior of water in rivers

Researchers developed a mathematical model that allows for anticipating the failure of dikes that hold in overflowing river water.

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This typhoon-resistant facility in Guam will power the tubes that give us the internet

A beach in Guam. (Photo by Luemen Carlson on Unsplash/) It's easy to forget that the internet isn't magic, and that it relies on very physical—almost banal—infrastructure to work. Hundreds of thousands of miles of undersea internet cables snake under the world's oceans, crossing the Atlantic , Pacific, and along the coast of South America. These insulated, garden hose-like lines carry the bulk of

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Author Correction: Sampling the volatile-rich transition zone beneath Bermuda

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1366-1 Author Correction: Sampling the volatile-rich transition zone beneath Bermuda

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The FDA says grain-free food could be killing dogs. Here’s what pet owners should know.

Get the facts to keep your pup safe. (Deposit Photos/) Last week the FDA made a scary announcement : grain-free food might be linked to a dangerous heart condition in dogs. This is actually the third update in a saga that's been going on since July 2018, when the FDA first began investigating the link. But they're not much closer to an answer, and there's been a lot of misinformation about the my

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Tracking down dark matter

Over time, scientists have developed different theories to explain exactly what the mysterious dark matter might be made of. Researchers have now found a way of detecting axions with the help of the Cosmic Axion Spin Precession Experiment (CASPEr) program. The basic assumption is that dark matter can influence the spin of nuclei, hence providing researchers with a way of tracking it down.

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Genetic variation linked to response to anxiety could inform personalized therapies

A new study in marmoset monkeys suggests that individual variation in genes alters our ability to regulate emotions, providing new insights that could help in the development of personaliszd therapies to tackle anxiety and depression.

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Misjudging the strength of other people's emotions based on egocentric bias

People of all ages tend to misjudge the strength of other people's emotions based on an egocentric bias, according to a new study.

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A new path to understanding second sound in Bose-Einstein condensates

There are two sound velocities in a Bose-Einstein condensate. In addition to the normal sound propagation there is second sound, which is a quantum phenomenon. Scientists have put forth a new theory for this phenomenon.

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Glow reveals dangerous bacteria

Salmonella and listeria are among the most widely distributed and deadliest causes of foodborne infections. Their rapid and reliable detection on food and industrial food processing equipment is very important. Scientists have introduced a new, ultrasensitive, chemiluminescence-based method for the direct detection of Salmonella and Listeria monocytogenes. Because of the simplicity and sensitivity

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The Atlantic Politics & Policy Daily: Print Deadline

Were you forwarded this email? Sign yourself up here. We have many other free email newsletters on a variety of other topics. Browse the full list. What We’re Following Today It’s Tuesday, July 2. ‣ House Democrats filed a lawsuit in federal court for President Donald Trump’s tax returns. In May, Treasury Secretary Steven Mnuchin rejected a subpoena for the documents that Democrats had issued. ‣

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