Molecular sensor scouts DNA damage and supervises repair
Using single-molecule imaging, researchers witness how molecules find and fix damaged DNA.
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Fruit flies find their way by setting navigational goals
Navigating fruit flies do not have the luxury of GPS, but they do have a kind of neural compass. In a new study, researchers found that the animals decide which way to turn by comparing this internal compass needle to a fixed goal.
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Beyond finding a gene: Same repeated stretch of DNA in three neurodegenerative diseases
Four different rare diseases are all caused by the same short segment of DNA repeated too many times, a mutation researchers call noncoding expanded tandem repeats. Researchers suspect variations of this type of mutation may cause other diseases that have thus far evaded diagnosis by genetic testing.Researchers are excited because instead of finding unique mutations in specific genes, they identif
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Risk of neural tube defects higher for babies of women on HIV therapy with dolutegrav
Children born to women on HIV therapy containing the drug dolutegravir since conception have a slightly higher risk of neural tube defects, compared to children born to women on regimens of other antiretroviral drugs.
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Tourist photographs are a cheap and effective way to survey wildlife
Tourists on safari can provide wildlife monitoring data comparable to traditional surveying methods, suggests research appearing July 22, 2019 in the journal Current Biology. The researchers analyzed 25,000 photographs from 26 tour groups to survey the population densities of five top predators (lions, leopards, cheetahs, spotted hyenas, and wild dogs) in northern Botswana, making it one of the fi
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Laugh tracks make 'dad jokes' funnier
Many people complain about television shows that use recorded laugh tracks. But researchers reporting in the journal Current Biology on July 22 have found that laugh tracks really do work.
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Unhatched chicks warn each other of danger
Inside their shells, they are picking up bad vibrations. Mark Bruer reports.
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When you spot 1 driving hazard, you may be missing another
When people notice one traffic hazard, they are less likely to see a simultaneous second hazard, according to new research. The finding has potential applications for both driver training and the development of automated, in-vehicle safety technologies.
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First impressions go a long way in the immune system
An algorithm that predicts the immune response to a pathogen could lead to early diagnosis for such diseases as tuberculosis.
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New deactivation mechanism for switch proteins detected
A new mechanism for the deactivation of switch proteins has been identified. Switch proteins such as Ras regulate many processes in the body and affect diseases such as cancer.
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Cell membranes: Sophisticated molecular machines in action
Almost all living organisms have gate-like protein complexes in their cell membranes that get rid of unwanted or life-threatening molecules. These ABC transporters are also responsible for resistance to antibiotics or chemotherapy. Researchers have now succeeded in decrypting all the stages of the transport mechanism.
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Overstuffed cancer cells may have an Achilles' heel
In a study using yeast cells and data from cancer cell lines, scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry genetic material. The vulnerability, they say, is rooted in a common feature among cancer cells — their high intracellular protein concentrations — that make them appear bloated and overstuffed, and
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Children with autism more likely to be bullied at home and at school, study finds
A major new study has found children with autism are more likely to be bullied by both their siblings and their peers, meaning that when they return from school, they have no respite from victimization.
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We Just Learned Baby Birds Communicate With Each Other From Inside Unhatched Eggs
This is so incredible.
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Ocean snail is first animal to be officially endangered by deep-sea mining
Nature, Published online: 22 July 2019; doi:10.1038/d41586-019-02231-1 Valuable metals and minerals pepper the creature's habitat, drawing commercial interest to the sea floor.
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Inhibition of bacterial ubiquitin ligases by SidJ–calmodulin-catalysed glutamylation
Nature, Published online: 22 July 2019; doi:10.1038/s41586-019-1440-8 Inhibition of bacterial ubiquitin ligases by SidJ–calmodulin-catalysed glutamylation
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Potential roles of gut microbiome and metabolites in modulating ALS in mice
Nature, Published online: 22 July 2019; doi:10.1038/s41586-019-1443-5 Potential roles of gut microbiome and metabolites in modulating ALS in mice
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Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase
Nature, Published online: 22 July 2019; doi:10.1038/s41586-019-1439-1 Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase
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Quantum-enhanced sensing of a single-ion mechanical oscillator
Nature, Published online: 22 July 2019; doi:10.1038/s41586-019-1421-y Number-state superpositions of the harmonic motion of a trapped beryllium ion are used to measure the oscillation frequency with quantum-enhanced sensitivity, achieving a mode-frequency uncertainty of about 10−6.
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Unhatched birds can warn others of danger by vibrating shells
Study finds developing chicks communicate with siblings when they hearalarm calls Baby seabirds that have not yet hatched communicate with their siblings in neighbouring eggs by vibrating their shells, scientists have discovered. A study of yellow-legged gulls revealed one of the most sophisticated known examples of embryonic communication. When exposed to the alarm calls of an adult bird respond
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Good for a laugh: canned laughter makes jokes seem funnier
Research finds recording of spontaneous laughter is more effective than controlled one In research that will ensure the sitcoms of the future are as painful as those broadcast today, scientists have found that canned laughter makes bad jokes seem funnier. The impact of overlaid laughter emerged from a study with autistic and "neurotypical" people, all of whom agreed to endure 40 jokes that were r
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10 billion years ago, the Milky Way ate Gaia
Modelling reveals the timing of a titanic encounter. Barry Keily reports.
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Plant-based diets could prevent type 2 diabetes
New study quantifies the protective effect. Natalie Parletta reports.
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Parasitic plants steal genes to become better parasites
Researchers reveal 'dramatic' functional horizontal gene transfer. Nick Carne reports.
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Unhatched chicks warn each other of danger
Inside their shells, they are picking up bad vibrations. Mark Bruer reports.
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Pinterest's New Search Tool Puts Stress Relief in Your Feed
Soon the company will begin placing anxiety-relieving exercises within its search results to help boost your mood.
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Bird Embryos Vibrate to Warn One Another of Danger before They Hatch
The egg-bound developing animals are more attuned to the outside world than previously thought — Read more on ScientificAmerican.com
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Bird Embryos Vibrate to Warn One Another of Danger before They Hatch
The egg-bound developing animals are more attuned to the outside world than previously thought — Read more on ScientificAmerican.com
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Quantum Darwinism, an Idea to Explain Objective Reality, Passes First Tests
It's not surprising that quantum physics has a reputation for being weird and counterintuitive. The world we're living in sure doesn't feel quantum mechanical. And until the 20th century, everyone assumed that the classical laws of physics devised by Isaac Newton and others — according to which objects have well-defined positions and properties at all times — would work at every scale. But Max Pl
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Molecular sensor scouts DNA damage and supervises repair
In the time it takes you to read this sentence, every cell in your body suffers some form of DNA damage. Without vigilant repair, cancer would run rampant, and now scientists at the University of Pittsburgh have gotten a glimpse of how one protein in particular keeps DNA damage in check.
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Parasitic plants use stolen genes to make them better parasites
Some parasitic plants steal genetic material from their host plants and use the stolen genes to more effectively siphon off the host's nutrients. A new study led by researchers at Penn State and Virginia Tech reveals that the parasitic plant dodder has stolen a large amount of genetic material from its hosts, including over 100 functional genes. These stolen genes contribute to dodder's ability to
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Miniaturized version of ribosome found in microsporidia
A research team lead by MIMS/SciLifeLab research group leader Jonas Barandun, Umeå University, Sweden, uses cryo-electron microscopy to provide near atomic details of the smallest known eukaryotic cytoplasmic protein synthesis machine, the microsporidian ribosome.
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Machine learning approach significantly expands inovirus diversity
To answer the question, "Where's Waldo?" readers need to look for a number of distinguishing features. Several characters may be spotted with a striped scarf, striped hat, round-rimmed glasses, or a cane, but only Waldo will have all of these features.
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Boosting a gut bacterium helps mice fight an ALS-like disease
Gut bacteria may alter ALS symptoms for good or ill.
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Increased control over ions' motions may help improve quantum computers
Scientists precisely manipulated the ion's oscillations and energy levels, a key step toward building better quantum computers.
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Understanding the drivers of a shift to sustainable diets
One of the 21st century's greatest challenges is to develop diets that are both sustainable for the planet and good for our bodies. An IIASA-led study explored the major drivers of widespread shifts to sustainable diets using a newly developed computational model of population-wide behavioral dynamics.
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Researchers suggest new approach needed to address Anthropocene risk
A team of international researchers led by Colorado State University is calling for a new approach to understanding environmental risks in the Anthropocene, the current geological age in which humans are a dominant force of change on the planet.
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Molecular sensor scouts DNA damage and supervises repair
In the time it takes you to read this sentence, every cell in your body suffers some form of DNA damage. Without vigilant repair, cancer would run rampant, and now scientists at the University of Pittsburgh have gotten a glimpse of how one protein in particular keeps DNA damage in check.
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New mechanism moving droplets at record-high speed and long distance without extra power
Transporting droplets on solid surfaces at high speed and long distances without additional force, even against gravity, is a formidable task. But a research team comprising scientists from City University of Hong Kong (CityU) and three other universities and research institutes has recently devised a novel mechanism to transport droplets at record-high velocity and distance without extra energy i
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Parasitic plants use stolen genes to make them better parasites
Some parasitic plants steal genetic material from their host plants and use the stolen genes to more effectively siphon off the host's nutrients. A new study led by researchers at Penn State and Virginia Tech reveals that the parasitic plant dodder has stolen a large amount of genetic material from its hosts, including over 100 functional genes. These stolen genes contribute to dodder's ability to
2d
Miniaturized version of ribosome found in microsporidia
A research team lead by MIMS/SciLifeLab research group leader Jonas Barandun, Umeå University, Sweden, uses cryo-electron microscopy to provide near atomic details of the smallest known eukaryotic cytoplasmic protein synthesis machine, the microsporidian ribosome.
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Machine learning approach significantly expands inovirus diversity
To answer the question, "Where's Waldo?" readers need to look for a number of distinguishing features. Several characters may be spotted with a striped scarf, striped hat, round-rimmed glasses, or a cane, but only Waldo will have all of these features.
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Laugh tracks do make us laugh – no joke
But it's better if it's real laughter, study suggests. Amelia Nichele reports
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Capturing more than just the moment
Tourists can help with wildlife monitoring.
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Bird Embryos Vibrate to Warn One Another of Danger before They Hatch
The egg-bound developing animals are more attuned to the outside world than previously thought — Read more on ScientificAmerican.com
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ORNL scientists make fundamental discovery to creating better crops
A team of scientists led by Oak Ridge National Laboratory have discovered the specific gene that controls an important symbiotic relationship between plants and soil fungi, and successfully facilitated the symbiosis in a plant that typically resists it.
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Characteristics in older patients associated with inability to return home after operation
The ACS NSQIP Geriatric Surgery Pilot Project has, for the first time, identified four factors in older patients that are associated with an inability to return home after an operation.
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Research in Regenerative Medicine proposes a quality control framework for umbilical cord blood-sourced allografts
The recent study from Burst Biologics challenges existing standards and outlines future safety and potency benchmarks.
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Enhanced recovery pathway for bariatric operations cuts hospital stays by half
A change in the care protocol of patients undergoing weight-reduction operations exceeded its desired effect by cutting postoperative hospital stays in half, reducing postoperative hospital readmissions by 38%, and reducing the amount of opioids the patients were sent home with by 95%, according to study results from a large bariatric and metabolic surgery center in Charleston, S.C.
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The architectural wonder of impermanent cities | Rahul Mehrotra
Every 12 years, a megacity springs up in India for the Kumbh Mela religious festival — what's built in ten weeks is completely disassembled in one. What can we learn from this fully functioning, temporary settlement? In a visionary talk, urban designer Rahul Mehrotra explores the benefits of building impermanent cities that can travel, adapt or even disappear, leaving the lightest possible footpr
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Elon Musk: Starship Super Heavy Will Have 41 Raptor Engines
The BFR While SpaceX's Starship prototype has yet to fly untethered — a test flight that's slated for later this week — CEO Elon Musk has big plans for the rocket: a "Super Heavy" variant of Starship, he says, will feature up to 41 Raptor engines. A Super Heavy Starship of that caliber would most certainly be the most powerful rocket ever built. "Starship Super Heavy with 35 Raptors," Musk tweete
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India Launches Chandrayaan-2 Moon Mission on Second Try
Last week, scientists abruptly called off the historic launch right before liftoff. A second attempt on Monday was a success.
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NASA Practices Space Gardening to Pack Lunchboxes for Mars
Astronauts would probably have to grow some of their own food to survive a round trip to Mars. Could a crop of chiles be the gateway to the future?
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For 50 Years Since Apollo 11, Presidents Have Tried to Take That Next Giant Leap
President Trump is only the latest to propose returning to the moon and then heading to Mars. But he faces the burdens of history to accomplish what his predecessors could not.
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Failure to launch: Parents are barriers to teen independence
National Poll: While most parents say they are doing enough to prepare their teen for adulthood, they gave low rankings of their teen's ability to handle basic tasks.
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New species of pocket shark identified
A team of researchers has identified a new species of pocket shark. The 5-and-a-half-inch male kitefin shark has been identified as the American Pocket Shark, or Mollisquama mississippiensis, based on five features not seen in the only other known specimen of this kind.
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Volcano eruption at different latitudes: A switch of hemispheric monsoon rainfall change
Volcanic eruptions eject sulfur dioxide gas high into the atmosphere, forming sulfate aerosol chemically, and block the incoming sunlight like an umbrella. This causes surface cooling globally, but the response of global monsoon rainfall is different following volcano eruptions at different latitudes, according to quantitative research by Meng Zuo, a doctoral student from the Institute of Atmosphe
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Når tvang tager styringen: Hvad sker der i hjernen, når du har OCD?
Frygten for at komme til at skade sig selv eller andre er en typisk tanke, som kører i ring for mange OCD-ramte.
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Targeting old bottleneck reveals new anticancer drug strategy
The enzyme ribonucleotide reductase is a bottleneck for cancer cell growth. Scientists at Winship Cancer Institute of Emory University have identified a way of targeting ribonucleotide reductase that may avoid the toxicity of previous approaches, informing focused drug discovery efforts.
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Are american nurses prepared for a catastrophe? New study says perhaps not
On average, American colleges and universities with nursing programs offer about one hour of instruction in handling catastrophic situations such as nuclear events, pandemics, or water contamination crises, according to two recent studies coauthored by a nursing professor at the University of Tennessee, Knoxville.
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Strongman leaders make for weak economies, study finds
A study of dictators over the past 150 years shows they are rarely associated with strong economies, and quite often with weaker ones.
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Archaeological evidence verifies long-doubted medieval accounts of First Crusade
The Univeristy of North Carolina at Charlotte-led archaeological dig on Jerusalem's Mount Zion has been going on for over a decade, looking at an area where there were no known ruins of major temples, churches or palaces, but nonetheless sacred land where three millennia of struggle and culture has long lain buried, evidence in layer upon layer of significant historical events.
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Strange stars that go supernova may be dimming because of dark matter
Some stars that go supernova are dimmer than we expect, so something must be filching their energy – it may be a possible dark matter particle called the axion
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Gun ownership linked to greater incidence of domestic homicides
A new study has reveals a unique and strong association between firearm ownership and the risk of domestic homicides. For each 10% increase in household gun ownership rates, the findings show a significant 13% increased incidence of domestic firearm homicide. The homicide risk differed across victim-offender relationships, with non-domestic firearm homicide rising only 2% among firearm owners.
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School readiness impaired in preschoolers with ADHD symptoms
Preschoolers with symptoms of attention-deficit hyperactivity disorder are much less likely than other children their age to be ready for school, new research has found.
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Russian website reportedly selling science article authorships
Several websites are reporting that a Russian website is selling authorships for research papers being published in several journals. Sites making such claims include retractionwatch.com and Science Chronicle—they are further claiming that the Web of Science group Clarivate Analytics has been investigating the Russian-based website—called 123mi.ru—and has found evidence that the group behind the s
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Courtship traditions led to the leggy African chicken
The choices that farmers in the Horn of Africa have made in selecting chickens has led to the genetically distinct African chicken, research finds. But the introduction of commercial birds threatens the 3,000-year-old local breed type and its longer, meatier legs. For generations, household farmers in the Horn of Africa have selectively chosen chickens with certain traits that make them more appe
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India Launches Mission To The Moon On Its 2nd Try
If Chandrayaan-2 reaches the moon as planned, India would become the fourth country to achieve a soft landing on the lunar surface, after the United States, Russia and China. (Image credit: Manish Swarup/AP)
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Making Things We Know Will Disappear
For those stifled by shades of perfectionism, temporary media can remind us how to create things for the fun of it — Read more on ScientificAmerican.com
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Archaeological evidence verifies long-doubted medieval accounts of First Crusade
New discoveries in the decade-long archaeological dig at Jerusalem's Mont Zion include a massive, long-rumored-but-buried earthwork, gold jewelry and war artifacts. The finds confirm previously unverified details from medieval historical accounts of the First Crusade — witness narratives of five-week siege, conquest, sack and massacre of the Fatamid (Muslim)-controlled city in July of 1099.
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When you spot one driving hazard, you may be missing another
When people notice one traffic hazard, they are less likely to see a simultaneous second hazard, according to new research from North Carolina State University. The finding has potential applications for both driver training and the development of automated, in-vehicle safety technologies.
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Solving the salt problem for seismic imaging
Automated imaging of underground salt bodies from seismic data could help streamline oil and gas exploration.
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Use of non-hospital-based provider-to-patient telehealth grew nearly 1,400%
From 2014 to 2018, private insurance claim lines for non-hospital-based provider-to-patient telehealth grew 1,393 %, according to a new white paper on telehealth from FAIR Health, a national, independent nonprofit organization dedicated to bringing transparency to healthcare costs and health insurance information. The study draws on data from FAIR Health's comprehensive repository of over 29 billi
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First impressions go a long way in the immune system
An algorithm that predicts the immune response to a pathogen could lead to early diagnosis for such diseases as tuberculosis
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New record: PLQE of 70.3% in lead-free halide double perovskites
A series of bulk lead-free mixed Bi-In halide double perovskites: Cs2AgBi1-xInxCl6 (0 < x < 1) breaks the parity-forbidden transition and retains direct band gap structure, having warm-white light emission, with photoluminescence quantum efficiency (PLQE) of 70.3%, much higher than the PLQE of reported lead perovskite materials. Additionally, the bulk material exhibits excellent stability on expos
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Scientists develop promising drug for treating ovarian, pancreatic cancers
Cancer scientists at Houston Methodist have been looking for more effective late-stage treatments for ovarian and pancreatic cancers and may have found one.
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Hot experiment brings molecular computing one step closer
The first measurement of heat transfer through a single molecule may be a step towards molecular computing. Molecular computing involves building circuits up from molecules rather than carving them out of silicon as a way to max out Moore's Law and make the most powerful conventional computers possible. Moore's Law began as an observation that the number of transistors in an integrated circuit do
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Our breath gets mosquitoes out for blood
Scientists have figured out how the mosquito brain uses signals from its visual and olfactory systems to identify, track, and home in on a host for its next blood meal. For a new study in Current Biology , researchers conducted behavioral experiments and real-time recording of the female mosquito brain and discovered that when the mosquito's olfactory system detects certain chemical cues, they tr
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New deactivation mechanism for switch proteins detected
A new mechanism for the deactivation of switch proteins has been identified by researchers from Ruhr-Universität Bochum, headed by Professor Klaus Gerwert and Dr. Till Rudack from the Department …
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Are Robots Coming for Our Jobs? Careful, It's a Trick Question
The robots are coming, and they'll probably take your job when they get here. Oh wait—have you heard that recently? As recently as, say, yesterday? In the news, or from a coworker, or in a sinister dystopian movie, maybe? Sounding the alarm about job losses to automation has become commonplace—in fact, it's more of a nonstop siren these days. Multiple Democratic presidential candidates are featur
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Sophisticated molecular machines in action
Almost all living organisms have gate-like protein complexes in their cell membranes that get rid of unwanted or life-threatening molecules. These ABC transporters are also responsible for resistance to antibiotics or chemotherapy. Researchers at Goethe University Frankfurt, together with the Max Planck Institute of Biophysics, which is also located in Frankfurt, have now succeeded in decrypting a
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Heart disease biomarker linked to paleo diet
People who follow the paleo diet have twice the amount of a key blood biomarker linked closely to heart disease, the world's first major study examining the impact of the diet on gut bacteria has found.
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New deactivation mechanism for switch proteins detected
A new mechanism for the deactivation of switch proteins has been identified by researchers from Ruhr-Universität Bochum, headed by Professor Klaus Gerwert and Dr. Till Rudack from the Department of Biophysics, and the University of Uppsala in Sweden. Switch proteins such as Ras regulate many processes in the body and affect diseases such as cancer.
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Studies show the influence of environment on the evolution of weeds
Rapid increases in herbicide resistance show that weeds can undergo important genetic changes over very brief periods of time. But herbicide use isn't the only factor influencing the evolution of weeds.
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Studies show the influence of environment on the evolution of weeds
Rapid increases in herbicide resistance show that weeds can undergo important genetic changes over very brief periods of time. But herbicide use isn't the only factor influencing the evolution of weeds.
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Astronomers map vast void in our cosmic neighborhood
An astronomer from the University of Hawaiʻi Institute for Astronomy (IfA) and an international team published a new study that reveals more of the vast cosmic structure surrounding our Milky Way galaxy.
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