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nyheder2019juli30

Scientists identify propranolol's target in treating rare condition and hemangiomas

The discovery of a new target for the blood-pressure medication propranolol may lead to the development of new and safer therapies for vascular diseases, according to new findings.

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Keeping parasites from sticking to mosquito guts could block disease transmission

Infections such as Chagas disease, African sleeping sickness, and leishmaniasis are caused by a group of microorganisms called kinetoplastids. In a new study, a research team used a non-disease-causing kinetoplastid to investigate how these parasites adhere to their insect hosts' insides. Their findings could help in the development of targeted therapies that prevent insects from transmitting thes

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Her er de kroniske sygdomme, der oftere rammer unge end ældre

Psykiske sygdomme som angst og OCD topper listen over de langvarige sygdomme, der primært rammer de 15-34 årige.

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Polyamory offers a unique opportunity to enjoy prolonged passion and closeness in romantic relationships

As everyone knows, the nature of romantic relationships usually changes over time. An early period of intense attraction tends to develop into a less fiery, deeper attachment bond. According to evolutionary arguments, the early stage, which typically lasts a few years, gives the pair the time and proximity that's required for developing a deeper nurturing, supportive – and predictable – relations

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Chance the Rapper Wants You to Get Married

It’s easy to root for Chance the Rapper, but it can still be hard to believe the variety of people who do. “What an album. Bravo,” tweeted New York City Mayor Bill de Blasio—whose last notable musical opinion was saying “ I love ska” on CNN —just hours after Chance’s The Big Day hit streaming services last Friday. In 2017, the New York Times ’ David Brooks, who once fretted about hip-hop’s themes

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The dirty secret about recycling: Most stuff that could be recycled isn’t

Humans buy a million plastic bottles a minute, and at least one-quarter never make their way into recycling bins. (Pixabay/) The EPA’s most recent census of U.S. waste tallied 262.4 million tons of new junk in 2015—the weight of about 40 Pyramids of Giza, ​or 4.5 pounds per person per day. We can recycle about one-​­quarter of what we toss, but rising costs and trade issues mean some municipaliti

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Alarming Surge in Drug-Resistant HIV Uncovered

The drug-resistant form of the virus has been detected at unacceptable levels across Africa, Asia and the Americas — Read more on ScientificAmerican.com

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Searching for the Key to Life's Beginnings

From exoplanets to chemical reactions, scientists inch closer to solving the great mystery of how life forms from inanimate matter

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Waste disposal genes may boost survival for sepsis

Researchers have found genes in mice that help cells survive exposure to cytokines during sepsis. Sepsis occurs when the body’s immune response to infection spirals out of control. Bacteria in the bloodstream trigger immune cells to release cytokines to quickly activate the body’s defenses. Sometimes the response goes overboard, creating a so-called “cytokine storm” that leaves people feverish or

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Space junk: A recycling station could be cleaning up in Earth orbit by 2050

There are about 22,000 large objects orbiting the Earth, including working and broken satellites and bits of old rocket from past space expeditions. If you include all the equipment dropped by astronauts while floating in space and the debris from colliding satellites down to around 1cm in size, there are about one million bits of space junk in Earth's orbit. These numbers are likely to be undere

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I, Too, Have Dressed Up as a Chicken to Harass British Politicians

A confession: Like Boris Johnson’s director of communications, Lee Cain, I, too, once dressed up in a giant, fluffy chicken costume to chase Conservative politicians around London. It wasn’t, I hasten to add, a private peccadillo—something I did in my own time, for my own kicks. No, like Cain, who was unmasked today as a former “ Mirror chicken,” I was a junior reporter at the Daily Mirror when t

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Gene transcripts from ancient wolf analyzed after 14,000 years in permafrost

RNA — the short-lived transcripts of genes — from the 'Tumat puppy', a wolf of the Pleistocene era has been isolated, and its sequence analyzed in a new study. The results establish the possibility of examining a range of RNA transcripts from ancient organisms, a possibility previously thought extremely unlikely because of RNA's short lifespan.

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How we care for the environment may have social consequences

Anyone can express their commitment to the environment through individual efforts, but some pro-environmental or 'green' behaviors may be seen as either feminine or masculine, which researchers say may have social consequences.

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p53 mutations in 10,000 cancer patients shed new light on gene's function

One of the most extensively studied genes in cancer, TP53 is well known for its role as a tumor suppressor. Researchers have conducted the most comprehensive study of TP53 mutations to better understand the processes leading to the inactivation of this important gene. Their findings shed light on how the gene becomes mutated and how those mutations can help predict clinical outlook.

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Causes of vitiligo (blotchy loss of skin color)

Researchers indicate that both genetic and environmental factors play significant roles in the onset of vitiligo, an autoimmune disease that results in the loss of color in blotches of skin.

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Where Do Psychiatrists Go when a Patient Dies?

I struggled with a terrible loss, and it made me realize that our field must do better — Read more on ScientificAmerican.com

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Where Do Psychiatrists Go when a Patient Dies?

I struggled with a terrible loss, and it made me realize that our field must do better — Read more on ScientificAmerican.com

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The Square Off Chess Set Lets Players Control Physical Pieces From Anywhere

With many products, you have a choice between digital and analogue. You can get an analogue watch with a dial and moving hands, or you can get smart watch with a digital touchscreen. You can read a physical book made out of paper and cardboard, or you can read a digital copy on your e-reader or tablet. You can play the vinyl LP of your favorite band’s new album, or you stream it on your phone. Ge

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Gene transcripts from ancient wolf analyzed after 14,000 years in permafrost

RNA — the short-lived transcripts of genes — from the 'Tumat puppy', a wolf of the Pleistocene era has been isolated, and its sequence analyzed in a new study by Oliver Smith of the University of Copenhagen and colleagues publishing on July 30 in the open-access journal PLOS Biology. The results establish the possibility of examining a range of RNA transcripts from ancient organisms, a possibili

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NHS 'health checks' reduce cardiovascular disease risk, new study finds

Attending a health check as part of the England National Health Services 'Health Check' program is associated with increased risk management interventions and decreased risk factors for cardiovascular disease in the six years following the check, according to a new study published this week in PLOS Medicine by Samah Alageel of King Saud University, Saudi Arabia, and colleagues from King's College

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Pre-eclampsia increases risk of end stage kidney disease, study finds

Women with pre-eclampsia during pregnancy have a five-fold increased risk of end stage kidney disease (ESKD) later in life compared to women who don't develop pre-eclampsia during pregnancy, according to a new study published this week in PLOS Medicine by Ali Khashan of University College Cork, Ireland, and colleagues at the Karolinska Institute, Sweden and Liverpool University, UK.

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Antenatal screening for kidney problems in early childhood

Babies who have persistent fluid-filled areas in their kidneys during gestation are likely to present with urinary tract problems and to be admitted to hospital in early childhood, according to new research published by Shantini Paranjothy and colleagues at Cardiff University, UK in the open access journal PLOS Medicine on July 30, 2019.

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Brand-brand competition is unlikely to reduce list prices of medicines

Greater brand-brand competition alone will likely not lower list prices of brand-name drugs in the US, according to a study published July 30 in the open-access journal PLOS Medicine by Ameet Sarpatwari of Brigham and Women's Hospital and Harvard Medical School, and colleagues.

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Fearful Parents Are Buying Bulletproof Backpacks for Their Kids

For parents in America, back-to-school shopping this year is about more than buying notebooks and binders — it’s about giving their child the best possible chance of surviving a school shooting. From Texas to Tennessee , Florida to Idaho , local news stations are reporting an uptick in the number of parents purchasing bulletproof backpacks for their kids in anticipation of the 2019 school year —

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4 Android home screens that will completely change the look of your phone

Come on—you can do better than a white background. (Matam Jaswanth via Unsplash/) If looking at a grid of icons on your phone has started to become boring, you don’t have to stay married to it. There are plenty of Android home screen launchers that go beyond the 5-by-5 grid and will completely change how you use your phone. I'm not talking about the typical, well-known ones like Nova Launcher , e

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Great White Attacks Another Shark! | Shark Week

After a shark bites down on their cage, the team witnesses a Great White attacking another shark! Stream Legend of Deep Blue on Discovery GO: https://go.discovery.com/tv-shows/shark-week/full-episodes/legend-of-deep-blue Own Full Seasons of Shark Week: https://play.google.com/store/tv/show/Shark_Week?id=gg81I7BZ-J4&hl=en_US Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Join us on Faceb

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Alcohol Companies Want to Make Disgusting Weed Drinks

One And Done Big beer companies are betting heavily on the future of drinkable THC, but it remains unclear exactly who they expect their customers to be. Right now, marijuana drinks on the market include seltzers, beers, and lemonades — and they’re all over the place in terms of THC content and generally pretty gross-tasting, according to an investigation by Amanda Chicago Lewis for The Verge . R

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p53 mutations in 10,000 cancer patients shed new light on gene's function

One of the most extensively studied genes in cancer, TP53 is well known for its role as a tumor suppressor. Researchers at Baylor College of Medicine have conducted the most comprehensive study of TP53 mutations to better understand the processes leading to the inactivation of this important gene. Their findings shed light on how the gene becomes mutated and how those mutations can help predict cl

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UA researcher and doctoral student reconcile scientific standoff in colon cancer research

Curtis Thorne, PhD, and UA doctoral student Carly Cabel validated findings from a 2018 collaborative study that identified a possible new therapeutic target for colon cancer — after a Harvard lab challenged the initial results.

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The Tender Power of Astrology Memes

In a recent post on Courtney Perkins’s Instagram account, two gray-haired women stand with their arms around each other, their gazes purposeful, their mouths unsmiling. It’s not clear who they are or what they’re doing, but the two have planned their outfits for the occasion: One woman is wearing a turquoise T-shirt that says I get us out of trouble in a white block print. Next to her, the second

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Faces of the 2019 Pan American Games

The 2019 Pan American Games started on July 26 in Lima, Peru, and will continue until August 11. More than 6,500 athletes from all over North and South America have gathered to compete in 419 events in 39 sports. Many photographers are on the scene as well, capturing the drama of the games, as competitors give their all in pursuit of a place on the podium during the medal ceremonies. Gathered her

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Not so bad after all: Credit default swaps cushion stock prices against credit downgrades

Credit default swaps (CDS) were heavily criticized for being a major contributor to the 2008/09 financial crisis.

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Plastics Or People? At Least 1 Of Them Has To Change To Clean Up Our Mess

As consumers rebel against plastic waste, there's a growing question: Do we invent something people can toss without harming the environment or do we change people by giving them a chance to reuse? (Image credit: Wayne Parry/AP)

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MediaTek Targets Gaming Smartphone Market With Helios G90 SoC

MediaTek has announced its latest SoCs for mobile devices, and it is aimed squarely at the gaming smartphone market. The new chipsets both fall into the G series and include the Helio G90 and …

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We Need a New Science of Progress

In 1861, the American scientist and educator William Barton Rogers published a manifesto calling for a new kind of research institution. Recognizing the “daily increasing proofs of the happy influence of scientific culture on the industry and the civilization of the nations,” and the growing importance of what he called “Industrial Arts,” he proposed a new organization dedicated to practical know

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Credit default swaps cushion stock prices against credit downgrades

Credit default swaps (CDS) were heavily criticized for being a major contributor to the 2008/09 financial crisis. But a new study shows that these market-based insurance tools have also served as a stabilizing force, protecting against stock price plunges and higher borrowing costs in the event a firm receives a downgrade from a credit rating agency.

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Students with a greater sense of school belonging are less likely to become bullies

Research has shown that, despite great efforts, one in three children continue to experience bullying in school. However, research also has indicated that environmental and psychological factors might play an important role in minimizing bullying behaviors.

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West Coast forest landowners will plant less Douglas-fir in warming climate, model shows

West Coast forest landowners are expected to adapt to climate change by gradually switching from Douglas-fir to other types of trees such as hardwoods and ponderosa pine, according to a new Oregon State University study.

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Groundwater policies fire up air pollution in northwest India

A measure to conserve groundwater in northwestern India has led to unexpected consequences: Added air pollution in an area already beset by haze and smog.

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NASA finds Flossie's center just north of coldest cloud tops

Cloud top temperatures provide information to forecasters about where the strongest storms are located within a tropical cyclone. NASA's Aqua satellite took Tropical Storm Flossie's cloud top temperatures to get that information.

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NASA analyzes first central pacific ocean hurricane's water vapor

Hurricane Erick has become the first tropical cyclone to enter the Central Pacific Ocean during the 2019 Hurricane Season and Hawaii is keeping an eye on the storm. NASA's Aqua satellite is also keeping eyes on Erick, too, and analyzed the water vapor content within the storm.

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How we care for the environment may have social consequences

Anyone can express their commitment to the environment through individual efforts, but some pro-environmental or "green" behaviors may be seen as either feminine or masculine, which Penn State researchers say may have social consequences.

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Conservation or construction? Deciding waterbird hotspots

Scientists show that conservation and construction decisions should rely on multiple approaches to determine waterbird 'hotspots,' not just on one analysis method as is often done.

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Students with a greater sense of school-belonging are less likely to become bullies

Researchers have found that students who feel a greater sense of belonging with their peers, family and school community are less likely to become bullies.

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Girls who are more physically active in childhood may have better lung function in adolescence

A study of more than 2,300 adolescents underscores the pulmonary health benefits of physical activity.

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A new tool uses AI to spot text written by AI

submitted by /u/trot-trot [link] [comments]

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Researchers enrich silver chemistry

Researchers from Russia and Saudi Arabia have proposed an efficient method for obtaining fundamental data necessary for understanding chemical and physical processes involving substances in the gaseous state. The proposed numerical protocol predicts the thermal effect of gas-phase formation of silver compounds and their absolute entropy. This includes first-ever such data for over 90 compounds. Th

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New studies by CU researchers highlight causes of vitiligo

A pair of new journal articles by researchers at the University of Colorado School of Medicine indicate that both genetic and environmental factors play significant roles in the onset of vitiligo, an autoimmune disease that results in the loss of color in blotches of skin.

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Disruption of glucose transport to rods and cones shown to cause vision loss in RP

Ophthalmology researchers at the University of Louisville have discovered the loss of vision in RP is the result of a disruption in the flow of nourishing glucose to the rods and cones. This disruption leads to the starvation of the photoreceptors. In addition, the failure in glucose metabolism in RP is similar to changes seen in lung cancer.

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NASA analyzes first central pacific ocean hurricane's water vapor

Hurricane Erick has become the first tropical cyclone to enter the Central Pacific Ocean during the 2019 Hurricane Season and Hawaii is keeping an eye on the storm. NASA's Aqua satellite is also keeping eyes on Erick, too, and analyzed the water vapor content within the storm.

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West Coast forest landowners will plant less Douglas-fir in warming climate, model shows

West Coast forest landowners are expected to adapt to climate change by gradually switching from Douglas-fir to other types of trees such as hardwoods and ponderosa pine.

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Leading oncologists and nutritionists pinpoint areas to catalyze nutrition-based cancer prevention

An international collaborative led by Ludwig Cancer Research and Cancer Research UK has identified key areas that are central to uncovering the complex relationship between nutrition and cancer.

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NASA finds Flossie's center just north of coldest cloud tops

Cloud top temperatures provide information to forecasters about where the strongest storms are located within a tropical cyclone. NASA's Aqua satellite took Tropical Storm Flossie's cloud top temperatures to get that information.

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Food quality control made faster and easier

Scientists at the Technical University of Munich (TUM) and the Leibniz-Institute for Food Systems Biology have developed a new methodology for the simultaneous analysis of odorants and tastants. It could simplify and accelerate the quality control of food in the future.

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Google Gives Android Auto A Fresh Look In Time For Summer Road Trips

Google is talking up a new look for Android Auto that comes only a couple of months after it was updated with dark mode and other new features. The update includes a new Android Auto app launcher …

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Exclusive: Can a supplement slow the natural processes of ageing?

A pill described as the only scientifically validated anti-ageing supplement has been designed to increase the number of years we spend in good health

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A New Way to Fight Crop Diseases, With a Smartphone

A hand-held device could help farmers identify blighted plants, and perhaps reduce agricultural losses. It’s like a strep test for tomatoes and tubers.

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Hacking self-driving cars could cause mass mayhem

A new simulation shows what it would take for future hackers to wreak widespread havoc by randomly stranding self-driving cars in a major city, researchers report. Imagine it’s the year 2026, at rush hour, and your self-driving car abruptly shuts down right where it blocks traffic. You climb out to see gridlock down every street in view, then a news alert on your watch tells you that hackers have

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People and place drive long-term citizen scientists

New research helps explain why people join citizen science projects and what motivates the citizen scientists who stick with it for years. The Coastal Observation and Seabird Survey Team , COASST, trains beachgoers along the West Coast, from California to Alaska, to monitor their local beach for dead birds. With about 4,500 participants in its 21-year history and roughly 800 active participants t

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Drake’s Troubling Reunion With Chris Brown

Last Friday, the R&B singer Chris Brown released the music video for his newest song, “ No Guidance, ” an aptly titled nine-minute work featuring the rapper Drake. The two had been teasing the arrival of this collaboration for at least a whole human gestation period. Last week, Brown tweeted a photo of the two with the caption “Somethings coming.” Drake most recently posted images of the duo part

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75% of asthma sufferers unable to work to their full potential

A new multi-national survey has revealed that asthma sufferers are missing nearly one-tenth of work hours due to their symptoms, which also results in a loss of productivity and affects their emotional wellbeing.

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From urine samples to precision medicine in bladder cancer through 3D cell culture

A research collaboration led by scientists from institutions in Japan including Tokyo University of Agriculture and Technology (TUAT) has developed a new experimental cancer model for dog bladder cancer. Urine samples were used for a 3D cell culture method called organoid culture. This method will allow us to quickly determine the proper chemotherapy and to identify new biomarkers of both dog and

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How we care for the environment may have social consequences

Anyone can express their commitment to the environment through individual efforts, but some pro-environmental or 'green' behaviors may be seen as either feminine or masculine, which Penn State researchers say may have social consequences.

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Students with a greater sense of school belonging are less likely to become bullies

Researchers at the University of Missouri have found that students who feel a greater sense of belonging with their peers, family and school community are less likely to become bullies.

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To conserve water, Indian farmers fire up air pollution

A measure to conserve groundwater in northwestern India has led to unexpected consequences: added air pollution in an area already beset by haze and smog.

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When mosquitoes are biting during rainy season, net use increases, study finds

The more rainfall a region in sub-Saharan Africa gets, the more mosquitoes proliferate there and the more likely its residents will sleep under their insecticide-treated bed nets to prevent malaria transmission, a new study from the Johns Hopkins Center for Communication Programs suggests.

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Conservation or construction? Deciding waterbird hotspots

MSU scientists show that conservation and construction decisions should rely on multiple approaches to determine waterbird 'hotspots,' not just on one analysis method as is often done.

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Antarctica ice flow map is super accurate

A new map of Antarctic ice velocity is the most precise ever created, researchers report. As reported in Geophysical Research Letters , the map, which researchers created using a quarter century’s worth of satellite data, is 10 times more accurate than previous renditions, covering more than 80 percent of the continent. “By utilizing the full potential of interferometric phase signals from satell

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Fly antimicrobial defence system doubles as tumour-killer

An antimicrobial agent called Defensin kills tumour cells and shrinks tumour size in fruit flies, with help from a pathway that flags the cells for destruction.

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If Wormholes Exist, Could We Really Travel Through Them?

Wormholes could offer a path to the most distant places in the universe. (Credit: dimonika/Shutterstock) Wormholes make the best shortcuts in the universe. That’s true in a literal sense, since the theoretical things can connect distant corners of the cosmos (or even different universes), allowing a traveler to go someplace without having to visit everywhere in between. But wormholes also present

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Congress May Ban “Addictive” Website Features Like Autoplay Videos

Addictive Design A new bill before the Senate aims to ban social media and tech platforms from implementing “addictive” designs and features — including autoplaying videos or endless scrolling. The Social Media Addiction Reduction Technology Act, introduced by Republican Senator Josh Hawley, would ban the types of features and tricks that these platforms use to keep people engaged for longer peri

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Fly antimicrobial defence system doubles as tumour-killer

An antimicrobial agent called Defensin kills tumour cells and shrinks tumour size in fruit flies, with help from a pathway that flags the cells for destruction.

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Google's Project Zero Finds Six 'Interactionless' iOS Vulnerabilities in iMessage App

Apple released bug fixes for five major security issues in iOS that can be exploited via its iMessage client app last week after they were discovered by researchers for competitor Google’s exploit-hunting …

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A real-time, click chemistry imaging approach reveals stimulus-specific subcellular locations of phospholipase D activity [Biochemistry]

The fidelity of signal transduction requires spatiotemporal control of the production of signaling agents. Phosphatidic acid (PA) is a pleiotropic lipid second messenger whose modes of action differ based on upstream stimulus, biosynthetic source, and site of production. How cells regulate the local production of PA to effect diverse signaling…

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Structural basis for adenylation and thioester bond formation in the ubiquitin E1 [Biochemistry]

The ubiquitin (Ub) and Ub-like (Ubl) protein-conjugation cascade is initiated by E1 enzymes that catalyze Ub/Ubl activation through C-terminal adenylation, thioester bond formation with an E1 catalytic cysteine, and thioester bond transfer to Ub/Ubl E2 conjugating enzymes. Each of these reactions is accompanied by conformational changes of the E1 domain…

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Site-specific phosphorylation of myosin binding protein-C coordinates thin and thick filament activation in cardiac muscle [Biochemistry]

The heart’s response to varying demands of the body is regulated by signaling pathways that activate protein kinases which phosphorylate sarcomeric proteins. Although phosphorylation of cardiac myosin binding protein-C (cMyBP-C) has been recognized as a key regulator of myocardial contractility, little is known about its mechanism of action. Here, we…

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PEAK3/C19orf35 pseudokinase, a new NFK3 kinase family member, inhibits CrkII through dimerization [Biochemistry]

Members of the New Kinase Family 3 (NKF3), PEAK1/SgK269 and Pragmin/SgK223 pseudokinases, have emerged as important regulators of cell motility and cancer progression. Here, we demonstrate that C19orf35 (PEAK3), a newly identified member of the NKF3 family, is a kinase-like protein evolutionarily conserved across mammals and birds and a regulator…

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Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity [Biochemistry]

TGFβ family ligands, which include the TGFβs, BMPs, and activins, signal by forming a ternary complex with type I and type II receptors. For TGFβs and BMPs, structures of ternary complexes have revealed differences in receptor assembly. However, structural information for how activins assemble a ternary receptor complex is lacking….

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Functional divergence caused by mutations in an energetic hotspot in ERK2 [Biochemistry]

The most frequent extracellular signal-regulated kinase 2 (ERK2) mutation occurring in cancers is E322K (E-K). ERK2 E-K reverses a buried charge in the ERK2 common docking (CD) site, a region that binds activators, inhibitors, and substrates. Little is known about the cellular consequences associated with this mutation, other than apparent…

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Improved detection of gene fusions by applying statistical methods reveals oncogenic RNA cancer drivers [Biophysics and Computational Biology]

The extent to which gene fusions function as drivers of cancer remains a critical open question. Current algorithms do not sufficiently identify false-positive fusions arising during library preparation, sequencing, and alignment. Here, we introduce Data-Enriched Efficient PrEcise STatistical fusion detection (DEEPEST), an algorithm that uses statistical modeling to minimize false-positives…

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Opening TRPP2 (PKD2L1) requires the transfer of gating charges [Biophysics and Computational Biology]

The opening of voltage-gated ion channels is initiated by transfer of gating charges that sense the electric field across the membrane. Although transient receptor potential ion channels (TRP) are members of this family, their opening is not intrinsically linked to membrane potential, and they are generally not considered voltage gated….

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Myosin IIA suppresses glioblastoma development in a mechanically sensitive manner [Cell Biology]

The ability of glioblastoma to disperse through the brain contributes to its lethality, and blocking this behavior has been an appealing therapeutic approach. Although a number of proinvasive signaling pathways are active in glioblastoma, many are redundant, so targeting one can be overcome by activating another. However, these pathways converge…

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Cardiomyocyte orientation modulated by the Numb family proteins-N-cadherin axis is essential for ventricular wall morphogenesis [Developmental Biology]

The roles of cellular orientation during trabecular and ventricular wall morphogenesis are unknown, and so are the underlying mechanisms that regulate cellular orientation. Myocardial-specific Numb and Numblike double-knockout (MDKO) hearts display a variety of defects, including in cellular orientation, patterns of mitotic spindle orientation, trabeculation, and ventricular compaction. Furthermor

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The TGF{beta} type I receptor TGF{beta}RI functions as an inhibitor of BMP signaling in cartilage [Developmental Biology]

The type I TGFβ receptor TGFβRI (encoded by Tgfbr1) was ablated in cartilage. The resulting Tgfbr1Col2 mice exhibited lethal chondrodysplasia. Similar defects were not seen in mice lacking the type II TGFβ receptor or SMADs 2 and 3, the intracellular mediators of canonical TGFβ signaling. However, we detected elevated BMP…

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Historical reconstruction unveils the risk of mass mortality and ecosystem collapse during pancontinental megadrought [Ecology]

An important new hypothesis in landscape ecology is that extreme, decade-scale megadroughts can be potent drivers of rapid, macroscale ecosystem degradation and collapse. If true, an increase in such events under climate change could have devastating consequences for global biodiversity. However, because few megadroughts have occurred in the modern ecological…

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Genetic control of male production in Daphnia pulex [Evolution]

Daphnia normally reproduce by cyclical parthenogenesis, with offspring sex being determined by environmental cues. However, some females have lost the ability to produce males. Our results demonstrate that this loss of male-producing ability is controlled by a dominant allele at a single locus. We identified the locus by comparing whole-genome…

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Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson’s disease [Immunology and Inflammation]

Type-1 reactions (T1R) are pathological inflammatory episodes and main contributors to nerve damage in leprosy. Here, we evaluate the genewise enrichment of rare protein-altering variants in 7 genes where common variants were previously associated with T1R. We selected 474 Vietnamese leprosy patients of which 237 were T1R-affected and 237 were…

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An immunometabolic pathomechanism for chronic obstructive pulmonary disease [Medical Sciences]

Chronic obstructive pulmonary disease (COPD) is an inflammatory condition associated with abnormal immune responses, leading to airflow obstruction. Lungs of COPD subjects show accumulation of proinflammatory T helper (Th) 1 and Th17 cells resembling that of autoreactive immune responses. As regulatory T (Treg) cells play a central role in the…

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CRISPR-Cas9-mediated gene knockout in intestinal tumor organoids provides functional validation for colorectal cancer driver genes [Medical Sciences]

Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide. Several genome sequencing studies have provided comprehensive CRC genomic datasets. Likewise, in our previous study, we performed genome-wide Sleeping Beauty transposon-based mutagenesis screening in mice and provided comprehensive datasets of candidate CRC driver genes. However, functional validation for…

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Conformational shifts in a chemoreceptor helical hairpin control kinase signaling in Escherichia coli [Microbiology]

Motile Escherichia coli cells use chemoreceptor signaling arrays to track chemical gradients with exquisite precision. Highly conserved residues in the cytoplasmic hairpin tip of chemoreceptor molecules promote assembly of trimer-based signaling complexes and modulate the activity of their CheA kinase partners. To explore hairpin tip output states in the serine…

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Asymmetric division yields progeny cells with distinct modes of regulating cell cycle-dependent chromosome methylation [Microbiology]

The cell cycle-regulated methylation state of Caulobacter DNA mediates the temporal control of transcriptional activation of several key regulatory proteins. Temporally controlled synthesis of the CcrM DNA methyltransferase and Lon-mediated proteolysis restrict CcrM to a specific time in the cell cycle, thereby allowing the maintenance of the hemimethylated state of…

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Mutagenesis of odorant coreceptor Orco fully disrupts foraging but not oviposition behaviors in the hawkmoth Manduca sexta [Neuroscience]

The hawkmoth Manduca sexta and one of its preferred hosts in the North American Southwest, Datura wrightii, share a model insect–plant relationship based on mutualistic and antagonistic life-history traits. D. wrightii is the innately preferred nectar source and oviposition host for M. sexta. Hence, the hawkmoth is an important pollinator…

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{beta}II-spectrin promotes mouse brain connectivity through stabilizing axonal plasma membranes and enabling axonal organelle transport [Neuroscience]

βII-spectrin is the generally expressed member of the β-spectrin family of elongated polypeptides that form micrometer-scale networks associated with plasma membranes. We addressed in vivo functions of βII-spectrin in neurons by knockout of βII-spectrin in mouse neural progenitors. βII-spectrin deficiency caused severe defects in long-range axonal connectivity and axonal degeneration….

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Defining the Kv2.1-syntaxin molecular interaction identifies a first-in-class small molecule neuroprotectant [Pharmacology]

The neuronal cell death-promoting loss of cytoplasmic K+ following injury is mediated by an increase in Kv2.1 potassium channels in the plasma membrane. This phenomenon relies on Kv2.1 binding to syntaxin 1A via 9 amino acids within the channel intrinsically disordered C terminus. Preventing this interaction with a cell and…

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A newly developed anesthetic based on a unique chemical core [Physiology]

Intravenous anesthetic agents are associated with cardiovascular instability and poorly tolerated in patients with cardiovascular disease, trauma, or acute systemic illness. We hypothesized that a new class of intravenous (IV) anesthetic molecules that is highly selective for the slow type of γ-aminobutyric acid type A receptor (GABAAR) could have potent…

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Molecular determinants of homo- and heteromeric interactions of Junctophilin-1 at triads in adult skeletal muscle fibers [Physiology]

In adult skeletal muscles, 2 junctophilin isoforms (JPH1 and JPH2) tether the sarcoplasmic reticulum (SR) to transverse tubule (T-tubule) membranes, generating stable membrane contact sites known as triads. JPHs are anchored to the membrane of the SR by a C-terminal transmembrane domain (TMD) and bind the T-tubule membrane through their…

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The MATH-BTB BPM3 and BPM5 subunits of Cullin3-RING E3 ubiquitin ligases target PP2CA and other clade A PP2Cs for degradation [Plant Biology]

Early abscisic acid signaling involves degradation of clade A protein phosphatases type 2C (PP2Cs) as a complementary mechanism to PYR/PYL/RCAR-mediated inhibition of PP2C activity. At later steps, ABA induces up-regulation of PP2C transcripts and protein levels as a negative feedback mechanism. Therefore, resetting of ABA signaling also requires PP2C degradation…

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Root-specific camalexin biosynthesis controls the plant growth-promoting effects of multiple bacterial strains [Plant Biology]

Plants in their natural ecosystems interact with numerous microorganisms, but how they influence their microbiota is still elusive. We observed that sulfatase activity in soil, which can be used as a measure of rhizosphere microbial activity, is differently affected by Arabidopsis accessions. Following a genome-wide association analysis of the variation…

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Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2 [Biochemistry]

Conformational selection by small molecules expands inhibitory possibilities for protein kinases. Nuclear magnetic resonance (NMR) measurements of the mitogen-activated protein (MAP) kinase ERK2 have shown that activation by dual phosphorylation induces global motions involving exchange between two states, L and R. We show that ERK inhibitors Vertex-11e and SCH772984 exploit…

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BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals [Biochemistry]

BCL-2 family proteins regulate the mitochondrial apoptotic pathway. BOK, a multidomain BCL-2 family protein, is generally believed to be an adaptor protein similar to BAK and BAX, regulating the mitochondrial permeability transition during apoptosis. Here we report that BOK is a positive regulator of a key enzyme involved in uridine…

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Three-dimensional structure of the basketweave Z-band in midshipman fish sonic muscle [Biophysics and Computational Biology]

Striated muscle enables movement in all animals by the contraction of myriads of sarcomeres joined end to end by the Z-bands. The contraction is due to tension generated in each sarcomere between overlapping arrays of actin and myosin filaments. At the Z-band, actin filaments from adjoining sarcomeres overlap and are…

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Girls’ comparative advantage in reading can largely explain the gender gap in math-related fields [Economic Sciences]

Gender differences in math performance are now small in developed countries and they cannot explain on their own the strong underrepresentation of women in math-related fields. This latter result is however no longer true once gender differences in reading performance are also taken into account. Using individual-level data on 300,000…

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Nitrogen sourcing during viral infection of marine cyanobacteria [Environmental Sciences]

The building blocks of a virus derived from de novo biosynthesis during infection and/or catabolism of preexisting host cell biomass, and the relative contribution of these 2 sources has important consequences for understanding viral biogeochemistry. We determined the uptake of extracellular nitrogen (N) and its biosynthetic incorporation into both virus…

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Development and evolution of age-dependent defenses in ant-acacias [Evolution]

Age-dependent changes in plant defense against herbivores are widespread, but why these changes exist remains a mystery. We explored this question by examining a suite of traits required for the interaction between swollen thorn acacias (genus Vachellia) and ants of the genus Pseudomyrmex. In this system, plants provide ants with…

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A genetic analysis of the Gibraltar Neanderthals [Genetics]

The Forbes’ Quarry and Devil’s Tower partial crania from Gibraltar are among the first Neanderthal remains ever found. Here, we show that small amounts of ancient DNA are preserved in the petrous bones of the 2 individuals despite unfavorable climatic conditions. However, the endogenous Neanderthal DNA is present among an…

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Spindle-shaped viruses infect marine ammonia-oxidizing thaumarchaea [Microbiology]

Ammonia-oxidizing archaea (AOA) from the phylum Thaumarchaeota are ubiquitous in marine ecosystems and play a prominent role in carbon and nitrogen cycling. Previous studies have suggested that, like all microbes, thaumarchaea are infected by viruses and that viral predation has a profound impact on thaumarchaeal functioning and mortality, thereby regulating…

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Neural substrates of sexual arousal are not sex dependent [Neuroscience]

Sexual arousal is a dynamical, highly coordinated neurophysiological process that is often induced by visual stimuli. Numerous studies have proposed that the cognitive processing stage of responding to sexual stimuli is the first stage, in which sex differences occur, and the divergence between men and women has been attributed to…

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Variability of signal sequences in turn-taking exchanges induces agency attribution in 10.5-mo-olds [Psychological and Cognitive Sciences]

Infants’ sensitivity to contingent reactivity as an indicator of intentional agency has been demonstrated by numerous referential gaze-following studies. Here we propose that variability of signal sequences in a turn-taking exchange provides an informative cue for infants to recognize interactions that may involve communicative information transfer between agents. Our experiment…

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Predicting neighborhoods’ socioeconomic attributes using restaurant data [Social Sciences]

Accessing high-resolution, timely socioeconomic data such as data on population, employment, and enterprise activity at the neighborhood level is critical for social scientists and policy makers to design and implement location-based policies. However, in many developing countries or cities, reliable local-scale socioeconomic data remain scarce. Here, we show an easily…

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Correction for Dendoncker et al., TNF-{alpha} inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile [Corrections]

GENETICS Correction for “TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile,” by Karen Dendoncker, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Joanna Lempiäinen, Evelien Van Hamme, Sylviane Dewaele, Sofie Vandevyver, Marlies Ballegeer, Jolien Souffriau, Lise Van Wyngene, Kelly Van Looveren, Tineke Vanderhaeghen, Rudi Beyaert, Ka

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In This Issue [This Week in PNAS]

Ecosystem impacts of megadroughts Drifting sand in semiarid eastern Australia. As the planet continues to warm, the magnitude of drought is likely to increase. However, the effects of megadroughts on animals, plants, and ecosystems are unclear. Robert Godfree et al. (pp. 15580–15589) developed a reconstruction of a severe, continent-wide megadrought…

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Measurement confounds in study on social media usage and adolescent life satisfaction [Social Sciences]

Billions of people engage with social media. Even small causal links with mental health outcomes can have enormous consequences. Orben et al. (1) recently published one of the largest (and certainly the longest) investigations of this topic to date. Their study is commendable in many ways. Unfortunately, their primary measure…

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Reply to Foster and Jackson: Open scientific practices are the way forward for social media effects research [Social Sciences]

Research investigating the effect of new technologies on adolescents is more often characterized by media hype than sound science. We therefore welcome Foster and Jackson’s (1) consideration of this research area’s measurement practices because we believe a critical mindset benefits academic, civic, and industry stakeholders. While the authors raised important…

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The problem with delineating narrow criteria for citizen science [Biological Sciences]

Heigl et al. (1) propose an international definition of citizen science based on quality criteria for projects. As an international group of scholars with extensive background in the theory and practice of citizen science, we find the Opinion by Heigl et al. (1) antithetical to the creativity, innovation, and bottom-up…

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Reply to Auerbach et al.: How our Opinion piece invites collaboration [Biological Sciences]

We thank Auerbach et al. (1) for taking the time to formulate their thoughts on our Opinion (2). We value this opportunity to jointly resolve an apparent misunderstanding of our Opinion piece. As the title “Toward an international definition of citizen science” suggests, our work is meant to be a…

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A speculative claim of mass mortalities of honeybee colonies caused by fipronil in France is not supported by published field data [Biological Sciences]

Holder et al. (1) speculate that fipronil (a phenylpyrazole insecticide), rather than imidacloprid (a neonicotinoid), caused mass mortalities of honeybees (Apis mellifera) in France. The paper provides laboratory experimental data contributing to the knowledge of the toxicity of fipronil and its sulfone metabolite to honeybees. However, its claim that “fipronil…

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Learning outside the box [Neuroscience]

Learning a new skill, whether it is riding a bicycle or playing chess, usually requires at least several days of practice if not much more. Due to experimental limitations, however, most neuroscience studies that attempt to unveil the neural representations of skill learning explore tasks that can be learned within…

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Closing the gap of ubiquitin activation [Biochemistry]

It is well appreciated that proteins are involved in all processes of life ranging from cell proliferation to cell survival and death. With such a wide spectrum of activities, which in many cases have opposing results, proteins must be tightly regulated to ensure the right outcome at the right time….

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Meddling with myosin’s mechanobiology in cancer [Cell Biology]

Nearly all cancers are diseases of uncontrolled cell growth coupled with dramatic changes in shape and motility. In fact, pathologists have used alterations in cellular and nuclear morphology to identify cancerous tissue for over a hundred years. These fundamental cellular processes—which in cancer also include invasion, dissemination, and secondary site…

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A dual role for {beta}II-spectrin in axons [Neuroscience]

Spectrins have been known for a long time as submembrane structural proteins, but a study from Lorenzo et al. (1) demonstrates an unexpected role for a neuronal spectrin in axonal transport. Actin and spectrins form specialized submembrane scaffolds important for the morphogenesis, compartmentation, and mechanical properties in a range of…

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Harnessing the interface mechanics of hard films and soft substrates for 3D assembly by controlled buckling [Applied Physical Sciences]

Techniques for forming sophisticated, 3D mesostructures in advanced, functional materials are of rapidly growing interest, owing to their potential uses across a broad range of fundamental and applied areas of application. Recently developed approaches to 3D assembly that rely on controlled buckling mechanics serve as versatile routes to 3D mesostructures…

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Encapsulation of hydrophobic components in dendrimersomes and decoration of their surface with proteins and nucleic acids [Chemistry]

Reconstructing the functions of living cells using nonnatural components is one of the great challenges of natural sciences. Compartmentalization, encapsulation, and surface decoration of globular assemblies, known as vesicles, represent key early steps in the reconstitution of synthetic cells. Here we report that vesicles self-assembled from amphiphilic Janus dendrimers, called…

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Flexible electronic/optoelectronic microsystems with scalable designs for chronic biointegration [Engineering]

Flexible biocompatible electronic systems that leverage key materials and manufacturing techniques associated with the consumer electronics industry have potential for broad applications in biomedicine and biological research. This study reports scalable approaches to technologies of this type, where thin microscale device components integrate onto flexible polymer substrates in interconnected arr

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A tensor-based framework for studying eigenvector multicentrality in multilayer networks [Engineering]

Centrality is widely recognized as one of the most critical measures to provide insight into the structure and function of complex networks. While various centrality measures have been proposed for single-layer networks, a general framework for studying centrality in multilayer networks (i.e., multicentrality) is still lacking. In this study, a…

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Background gamma radiation and soil activity measurements in the northern Marshall Islands [Environmental Sciences]

We report on measurements of external gamma radiation on 9 islands in 4 atolls in the northern Marshall Islands, all of which were affected by the US nuclear testing program from 1946 to 1958 (Enjebi, Ikuren, and Japtan in Enewetak Atoll; Bikini and Enyu in Bikini Atoll; Naen in Rongelap…

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Using hominin introgression to trace modern human dispersals [Genetics]

The dispersal of anatomically modern human populations out of Africa and across much of the rest of the world around 55 to 50 thousand years before present (ka) is recorded genetically by the multiple hominin groups they met and interbred with along the way, including the Neandertals and Denisovans. The…

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New horizons at L’Anse aux Meadows [Anthropology]

The UNESCO World Heritage site of L’Anse aux Meadows (LAM) in northern Newfoundland is the only undisputed site of pre-1492 presence of Europeans in the Americas. In August 2018, we undertook fieldwork at LAM to sample the peat bog 30 m east of the Norse ruins for a multiproxy paleoenvironmental…

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Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation [Applied Biological Sciences]

Mesenchymal stem cell (MSC) therapies demonstrate particular promise in ameliorating diseases of immune dysregulation but are hampered by short in vivo cell persistence and inconsistencies in phenotype. Here, we demonstrate that biomaterial encapsulation into alginate using a microfluidic device could substantially increase in vivo MSC persistence after intravenous (i.v.) injection….

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Learning data-driven discretizations for partial differential equations [Applied Mathematics]

The numerical solution of partial differential equations (PDEs) is challenging because of the need to resolve spatiotemporal features over wide length- and timescales. Often, it is computationally intractable to resolve the finest features in the solution. The only recourse is to use approximate coarse-grained representations, which aim to accurately represent…

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The Mpemba effect in spin glasses is a persistent memory effect [Applied Physical Sciences]

The Mpemba effect occurs when a hot system cools faster than an initially colder one, when both are refrigerated in the same thermal reservoir. Using the custom-built supercomputer Janus II, we study the Mpemba effect in spin glasses and show that it is a nonequilibrium process, governed by the coherence…

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Ultraefficient thermophotovoltaic power conversion by band-edge spectral filtering [Applied Physical Sciences]

Thermophotovoltaic power conversion utilizes thermal radiation from a local heat source to generate electricity in a photovoltaic cell. It was shown in recent years that the addition of a highly reflective rear mirror to a solar cell maximizes the extraction of luminescence. This, in turn, boosts the voltage, enabling the…

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Intrinsically motivated collective motion [Applied Physical Sciences]

Collective motion is found in various animal systems, active suspensions, and robotic or virtual agents. This is often understood by using high-level models that directly encode selected empirical features, such as coalignment and cohesion. Can these features be shown to emerge from an underlying, low-level principle? We find that they…

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Fluorescence spectral shape analysis for nucleotide identification [Chemistry]

We report a conjugated polyelectrolyte fluorescence-based biosensor P-C-3 and a general methodology to evaluate spectral shape recognition to identify biomolecules using artificial intelligence. By using well-defined analytes, we demonstrate that the fluorescence spectral shape of P-C-3 is sensitive to minor structural changes and exhibits distinct signature patterns for different analytes….

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Science and Culture: Light-seeking mobile houseplants raise big questions about the future of technology [Engineering]

Houseplants on wheels roamed the hallways of Rutgers University in New Jersey, beginning in 2012, sunning themselves in bright windows and asking students for water when their soil was dry. No remote control directed them. No unseen hand guided their movement. The mobile plants, called FloraBorgs, drove themselves. Light-sensing plants…

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In situ measurement of cesium-137 contamination in fruits from the northern Marshall Islands [Environmental Sciences]

Radioactive contamination of fruits in the northern Marshall Islands, resulting from the US nuclear weapons testing program in the 1940s and 1950s, is still a human health concern, in particular pertaining to island population resettlement and the economic benefit from farming. Over 200 fruits, primarily coconuts and pandanus, were collected…

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Radiation maps of ocean sediment from the Castle Bravo crater [Environmental Sciences]

On March 1, 1954, the United States conducted its largest thermonuclear weapon test in Bikini Atoll in the Marshall Islands; the detonation was code-named “Castle Bravo.” Radioactive deposits in the ocean sediment at the bomb crater are widespread and high levels of contamination remain today. One hundred thirty cores were…

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How to Watch the Second 2020 Democratic Primary Debate

The Democratic primary debates return Tuesday and Wednesday, and this time they're happening in Detroit. Here's how to watch and what to look for.

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Keeping parasites from sticking to mosquito guts could block disease transmission

Infections such as Chagas disease, African sleeping sickness, and leishmaniasis are caused by a group of microorganisms called kinetoplastids. In a new study, a research team from Penn and Penn State Brandywine used a non-disease-causing kinetoplastid to investigate how these parasites adhere to their insect hosts' insides. Their findings could help in the development of targeted therapies that pr

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CHOP research team redefines the footprint of viral vector gene therapy

Building on a track record of developing adeno-associated viral (AAV) vectors as a groundbreaking clinical tool for gene therapy and gene editing, Children's Hospital of Philadelphia (CHOP) researchers report a more sensitive method for capturing the footprint of AAV vectors — a broad range of sites where the vectors transfer genetic material.

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Scientists identify propranolol's target in treating rare condition and hemangiomas

The discovery of a new target for the blood-pressure medication propranolol may lead to the development of new and safer therapies for vascular diseases, according to new findings published in eLife.

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Fly antimicrobial defence system doubles as tumour-killer

An antimicrobial agent called Defensin kills tumour cells and shrinks tumour size in fruit flies, with help from a pathway that flags the cells for destruction.

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Selective antibiotics following nature's example

Chemists from Konstanz develop selective agents to combat infectious diseases — based on the structures of natural products

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Birth at Safari Park marks milestone in saving nearly extinct rhino

Victoria the southern white rhino is now happily bonding with her healthy newborn son at the San Diego Zoo Safari Park. And with that birth on Sunday, the prospects for rescuing their nearly extinct kin have brightened.

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Birth at Safari Park marks milestone in saving nearly extinct rhino

Victoria the southern white rhino is now happily bonding with her healthy newborn son at the San Diego Zoo Safari Park. And with that birth on Sunday, the prospects for rescuing their nearly extinct kin have brightened.

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Study: Icy Planets Could Be Warm Enough to Harbor Life

Hoth Boi Clique New research by a team of astronomers at the University of Toronto suggests that extraterrestrial life could survive on icy planets which, until now, were thought to be too cold. The researchers ran thousands of simulations to explore the temperature fluctuations of planets inside habitable zones — the range of distances from a central star where planets with Earth-like liquid wat

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Beyond the bottom line: Investors favour companies that give back

Savvy business leaders understand that when companies give back, they can attract better employees and win customers. But a new study shows they're not only doing it to impress workers and consumers: they're also doing it to boost their bottom line.

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Researchers confirm that people judge entire groups based on the performance of its 'first member'

People are more likely to judge the performance of a group based on member's that are labelled as first or number one than they are on any other member, according to new research led by Cass Business School academic Dr. Janina Steinmetz.

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Legal status no guarantee of job security

Legal status is no guarantee that migrants will find more security in the workplace, according to a new study published in the journal Migration Letters.

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Asian countries turning back wealthy world's waste

Several Southeast Asian countries, sick of being the wealthy world's rubbish dump, have in recent weeks turned back container-loads of waste from foreign shores.

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Before building another telescope, learn from Hawaiian culture

Amid continued protests over the construction of the Thirty Metre Telescope on Mauna Kea, Haunani Kane suggests scientists can learn from Hawaiian culture

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Genetic analysis reveals Vikings had a wide and diverse family tree

Many Vikings were descendants of people from outside Scandinavia who moved into the region before and during the Viking Age

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Daily briefing: A dying tectonic plate is ripping apart

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02341-w A rip in the Juan de Fuca tectonic plate might be causing earthquakes and volcanoes, scientists using CRISPR gene editing to transform China’s food supply and an alarming surge in drug-resistant HIV.

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Capital One Hacker Arrested After Bragging About Theft on Twitter

Not So Smart In March, a hacker breached Capital One’s server, stealing tens of thousands of Social Security and bank account numbers in a massive attack that affected more than 100 million people. On Monday, Capital One announced that the FBI had arrested Seattle software engineer Paige Thompson for the crime — after they caught her bragging about it on her social media accounts. Face Palm Capit

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Hundreds of volunteers help save five whales stranded off Florida beach

Five pilot whales stranded in shallow water on a Florida beach were rescued Monday afternoon thanks to the efforts of scientists, the Coast Guard, and a small army of beachgoers who volunteered to help.

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3 Things to Watch as Summer Heat Bakes the Arctic

Sea ice levels are running very low as wildfires rage — Read more on ScientificAmerican.com

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Hundreds of volunteers help save five whales stranded off Florida beach

Five pilot whales stranded in shallow water on a Florida beach were rescued Monday afternoon thanks to the efforts of scientists, the Coast Guard, and a small army of beachgoers who volunteered to help.

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Skin in balance: Joint forces of polarity and cell mechanics

Molecular mechanics in the skin of mice are driven by polarity genes, a team led by Sandra Iden of the Cluster of Excellence for Aging Research CECAD reports in 'Nature Communications'.

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Sexual competition helps horned beetles survive deforestation

A study of how dung beetles survive deforestation in Borneo suggests that species with more competition among males for matings are less likely to go extinct, according to research led by scientists from Queen Mary University of London and Nanyang Technological University, Singapore.

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A first bad apple spoils the bunch

People are more likely to judge the performance of a group based on member's that are labelled as first or number one than they are on any other member, according to new research led by Cass Business School academic Dr Janina Steinmetz.

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FEFU scientists trained robots to make independent decisions in a changing environment

A team of scientists from the School of Engineering of Far Eastern Federal University, Institute of Marine Technology Issues, and Institute of Automation and Management Processes of the Far Eastern Branch of the Russian Academy of Sciences developed software allowing industrial AI robots with technical vision to set out and adjust the movement trajectories of their tools in real time without reduc

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Legal status no guarantee of job security

Legal status is no guarantee that migrants will find more security in the workplace, according to a new study published in the journal Migration Letters.

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A paradoxical proinflammatory effect of endocannabinoids in the brain discovered

The results of the study in mice are contrary to what had been observed to date in other areas of the brain where endocannabinoids play an anti-inflammatory role.

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Beyond the bottom line: Investors favour companies that give back

Savvy business leaders understand that when companies give back, they can attract better employees and win customers. But a new study shows they're not only doing it to impress workers and consumers: they're also doing it to boost their bottom line.

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Improving efficiency, brightness of perovskite LEDs

Advances in organic phosphorescent materials are opening new opportunities for organic light-emitting diodes for combined electronics and light applications, including solar cells, photodiodes, optical fibers and lasers. While low-dimensional luminescent materials, like the calcium titanium oxide mineral perovskite, have promising optical properties, their performance remains insufficient compared

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Treating solar cell materials reveals formation of unexpected microstructures

Hybrid organic-inorganic perovskites have been used in optoelectronic devices including solar cells, photodetectors, light-emitting diodes and lasers, but the surface of hybrid perovskites is prone to surface defects, where charge carriers are trapped in the semiconducting material. To solve this problem, the crystal surface must be passivated. Researchers describe testing hybrid organic-inorganic

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Estrogens and Memory Loss in Women

Research suggests that the family of hormones has a crucial role in the hippocampus — Read more on ScientificAmerican.com

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Estrogens and Memory Loss in Women

Research suggests that the family of hormones has a crucial role in the hippocampus — Read more on ScientificAmerican.com

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The iconic Joshua Tree is in trouble

Desert sky at Joshua Tree National Park. (Pixabay/) Botanist Lynn Sweet regularly treks through California's Joshua Tree National Park , nearly 800,000 acres that lie at the intersection of the Mojave and Colorado deserts. She likes to photograph the gnarly, spikey-limbed trees, which look—as some have observed —like a picture from a Dr. Seuss children's book. Much as many of the park’s million o

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There have been more than 1000 cases of measles in the US this year

Measles cases are rising in the US at an alarming rate. There have now been 1164 this year, which is the highest year on record since 1992

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The Mako's Race Against Extinction | Shark Week's The Daily Bite

On today's episode The Daily Bite, Luke Tipple explains how the fastest sharks in the ocean are racing against extinction. Stream Full Episodes from Shark Week: https://go.discovery.com/tv-shows/shark-week/ Own Full Seasons of Shark Week: https://play.google.com/store/tv/show/Shark_Week?id=gg81I7BZ-J4&hl=en_US Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Join us on Facebook: https://w

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Sense of belonging makes kids less likely to bully

Students who feel a greater sense of belonging with their peers, family, and school community are less likely to participate in bullying, according to new research. Previous research has shown that, despite great efforts, one in three children continue to experience bullying in school. However, research has also indicated that environmental and psychological factors might play an important role i

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Magic Mushroom Coffee and Tea Coming to a Pot Near You?

submitted by /u/mbolaris [link] [comments]

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Collective Intelligence Will End Identity-Based Politics – Facts So Romantic

It is possible to imagine, explore, and promote forms of consciousness that enhance awareness as well as dissolve the artificial illusions of self and separate identity. Photo illustration by Shane Taremi / Flickr The Canadian poet Dennis Lee once wrote that the consolations of existence might be improved if we thought, worked, and lived as though we were inhabiting “the early days of a better ci

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Estrogens and Memory Loss in Women

Research suggests that the family of hormones has a crucial role in the hippocampus — Read more on ScientificAmerican.com

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Did Russia Cover Up a Radiation Leak 100x Worse Than Fukushima?

Nuclear Detectives A massive radiation leak, up to 100 times worse than the 2011 Fukushima power plant meltdown in Japan, plumed over Europe back in 2017. At the time, it was traced back to a Russian nuclear facility — but Russia denied any involvement . Now, new research confirms that the original hunch was correct, New Scientist reports . The study, published this week in the journal PNAS, conc

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Ethiopia Says It Planted Over 350 Million Trees in a Day, a Record

The initiative is part of a campaign by the prime minister to plant four billion trees in the country before the fall to combat deforestation and global warming.

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Neuroscientists decode brain speech signals into written text

Study funded by Facebook aims to improve communication with paralysed patients Doctors have turned the brain signals for speech into written sentences in a research project that aims to transform how patients with severe disabilities communicate in the future. The breakthrough is the first to demonstrate how the intention to say specific words can be extracted from brain activity and converted in

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Why are we so drawn to places of happy memories?

Scientists identified astrocytic MORs in the hippocampus are key to conditioned place preference.

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Treating solar cell materials reveals formation of unexpected microstructures

Hybrid organic-inorganic perovskites have been used in optoelectronic devices including solar cells, photodetectors, light-emitting diodes and lasers, but the surface of hybrid perovskites is prone to surface defects, where charge carriers are trapped in the semiconducting material. To solve this problem, the crystal surface must be passivated. Researchers describe testing hybrid organic-inorganic

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Improving efficiency, brightness of perovskite LEDs

Advances in organic phosphorescent materials are opening new opportunities for organic light-emitting diodes for combined electronics and light applications, including solar cells, photodiodes, optical fibers and lasers. While low-dimensional luminescent materials, like the calcium titanium oxide mineral perovskite, have promising optical properties, their performance remains insufficient compared

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Technological developments in radiation detectors enhance global nuclear security

Nuclear power plants can withstand most inclement weather and do not emit harmful greenhouse gases. However, trafficking of the nuclear materials to furnish them with fuel remains a serious issue as security technology continues to be developed. Two physicists conducted research to enhance global nuclear security by improving radiation detectors. According to them, improving radiation detectors re

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Finding a cause of neurodevelopmental disorders

Neurodevelopmental disorders arising from rare genetic mutations can cause atypical cognitive function, intellectual disability, and developmental delays, yet it is unclear why and how this happens. Scientists suspected a mutation in a complex of proteins could be the culprit for a group of rare genetic disorders and, now, Salk Institute researchers have identified the molecular mechanism linking

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At the edge of chaos: New method for exoplanet stability analysis

Gaining a full understanding of systems of exoplanets and distant stars is difficult, because the initial positions and velocities of the exoplanets are unknown. Determining whether the system dynamics are quasi-periodic or chaotic is cumbersome, expensive and computationally demanding. In this week's Chaos, Tamás Kovács delivers an alternative method for stability analysis of exoplanetary bodies

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Microfluidic array catches, holds single cervical cells for faster screening

Several screening tests for cervical cancer have been developed in recent years. One technique uses immunofluorescent staining to determine the levels of biomarkers to indicate a cell is undergoing HPV-related cancerous growth. Immunostaining for these proteins, however, can be time-intensive. One new approach, discussed in this week's Biomicrofluidics, looks to provide a way to screen cervical ce

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How Mitch McConnell Persuaded a Senior House Democrat to Back Impeachment

Updated on July 30, 2019 at 2:46 p.m. ET On its face, Robert Mueller’s testimony last week didn’t seem likely to transform the political dynamic surrounding the impeachment of Donald Trump. The former special counsel offered no dramatic answers or riveting sound bites to galvanize the American public, as Democrats had hoped he would, and he mostly refused to expound on his investigation beyond th

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Technological developments in radiation detectors enhance global nuclear security

Nuclear power plants can withstand most inclement weather and do not emit harmful greenhouse gases. However, trafficking of the nuclear materials to furnish them with fuel remains a serious issue as security technology continues to be developed. Physicists conducted research to enhance global nuclear security by improving radiation detectors. According to them, improving radiation detectors requir

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Finding a cause of neurodevelopmental disorders

Neurodevelopmental disorders arising from rare genetic mutations can cause atypical cognitive function, intellectual disability, and developmental delays, yet it is unclear why and how this happens. Scientists suspected a mutation in a complex of proteins could be the culprit for a group of rare genetic disorders and now, researchers have identified the molecular mechanism linking this mutation wi

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At the edge of chaos: New method for exoplanet stability analysis

Gaining a full understanding of systems of exoplanets and distant stars is difficult, because the initial positions and velocities of the exoplanets are unknown. Determining whether the system dynamics are quasi-periodic or chaotic is cumbersome, expensive and computationally demanding. Scientists deliver an alternative method for stability analysis of exoplanetary bodies using only the observed t

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Faulty brain circuits repaired using nanotechnology

Working with mouse and human tissue, researchers report new evidence that a protein pumped out of some — but not all — populations of 'helper' cells in the brain, called astrocytes, plays a specific role in directing the formation of connections among neurons needed for learning and forming new memories.

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New study reveals how TB bacteria may survive in human tissues

Microbiologists have discovered that some pathogens depend on carbon monoxide to survive when other nutrients are not available.

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Next-generation medication: Where chemistry meets computation

A group of researchers drastically enhanced and sped up the way to skeletally diverse indole alkaloids, composed of the medicinally-relevant scaffolds. By leveraging computational and synthetic approaches, this group has successfully developed a concise and versatile synthetic process generating the densely-functionalized multicyclic complex scaffolds, which would facilitate the development of bot

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Analysis reveals economic cost of Alzheimer's disease and dementia are 'tip of the iceberg'

A new research review highlighting the hidden costs of dementia suggests that traditional measures only show the 'tip of the iceberg' of the cost impact on society.

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Stomach acid-reducing drugs may raise risk of future allergies – study

Lead scientist hopes findings raise awareness about proton-pump inhibitors’ side-effects Prescription medicines to reduce stomach acid are associated with an increased risk of developing allergies, according to a study. The research suggests people prescribed proton-pump inhibitors (PPIs) are twice as likely to be prescribed anti-allergy drugs in future years. Continue reading…

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AI Decodes Speech and Hearing Based on Brain Activity

The proof-of-concept study could be a step toward better assisted communication devices for paralyzed people.

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Facebook is funding brain experiments to create a device that reads your mind

Big tech firms are trying to read people’s thoughts, and no one’s ready for the consequences.

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‘Mind-reading’ may help those who cannot speak

Decoding brain signals can make conversation possible. Mark Bruer reports.

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This Human Gene Editing Trial Will Use CRISPR to Treat Blindness

CRISPR Drawer Up to 18 people, ages three and up, will be part of the first ever human study in the U.S. that uses the gene-editing technique CRISPR inside the body. The goal is to treat an eye disorder that causes blindness, according to the Associated Press . In many cases the heritable disorder, Leber congenital amaurosis (LCA), eventually causes complete loss of vision. In fact, it’s the numb

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Cigarette smoke makes MRSA superbug bacterium more drug-resistant

Cigarette smoke can make MRSA bacterial strains more resistant to antibiotics, new research has shown.

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Ultra-thin layers of rust generate electricity from flowing water

Researchers have shown that iron oxide layers can convert kinetic energy of saltwater into electrical power.

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3D printed rocket fuel comparison

Scientists in Australia are using 3D printing to create fuels for rockets, and using tailor-made rocket motors they've built to test the fuels.

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Stressed at school? Art therapy reduces teenage girls' headaches

In a pilot study, researchers explored art-based mindfulness activities that schools could use to reduce headaches, a common side effect of stress in adolescent girls. After three weeks of twice-weekly mindfulness and art therapy sessions, 8 teenage girls reported experiencing significantly fewer headaches.

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New material could make it easier to remove colon polyps

Researchers have developed a gel that can be injected into the tissue lining the colon, forming a 'cushion' that makes it easier to remove precancerous polyps during a colonoscopy.

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Individuals with obesity get more satisfaction from their food

A new study found no significant difference in taste perceptions between participants of normal weight and those who were overweight. However, participants with obesity had initial taste perceptions that were greater than participants who were not obese, which declined at a more gradual rate than participants who were not obese. This quantification of satisfaction from food may help explain why so

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Can antacids boost allergy risk?

Study of prescription data suggests association

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Microfluidic array catches, holds single cervical cells for faster screening

Several screening tests for cervical cancer have been developed in recent years. One technique uses immunofluorescent staining to determine the levels of biomarkers to indicate a cell is undergoing HPV-related cancerous growth. Immunostaining for these proteins, however, can be time-intensive. One new approach, discussed in this week's Biomicrofluidics, looks to provide a way to screen cervical ce

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Improving efficiency, brightness of perovskite LEDs

Advances in organic phosphorescent materials are opening new opportunities for organic light-emitting diodes for combined electronics and light applications, including solar cells, photodiodes, optical fibers and lasers.

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Treating solar cell materials reveals formation of unexpected microstructures

Recent advances in solar cell technology use polycrystalline perovskite films as the active layer, with an increase to efficiency of as much as 24.2%. Hybrid organic-inorganic perovskites are especially successful, and they have been used in optoelectronic devices including solar cells, photodetectors, light-emitting diodes and lasers.

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At the edge of chaos: New method for exoplanet stability analysis

Exoplanets revolving around distant stars are coming quickly into focus with advanced technology like the Kepler space telescope. Gaining a full understanding of those systems is difficult, because the initial positions and velocities of the exoplanets are unknown. Determining whether the system dynamics are quasi-periodic or chaotic is cumbersome, expensive and computationally demanding.

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Researchers identify prime compound candidates for new room temperature semiconductor radiation detectors

Nuclear power plants can withstand most inclement weather and do not emit harmful greenhouse gases. However, trafficking of the nuclear materials to furnish them with fuel remains a serious issue as security technology continues to be developed.

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Exploring the Great Mysteries of Consciousness and Free Will With Annaka Harris

For thousands of years, humankind has been plagued by to two essential questions: Why do I have this unique voice inside my head? And am I in control of it or am I simply a passenger? The concepts of consciousness and free will are fundamental to the human condition—perhaps the two most crucial operating principles of our lives. And yet, after millennia of philosophical inquiry and scientific pro

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How policewomen make communities safer | Ivonne Roman

Less than 13 percent of police officers in the United States are women — despite their proven effectiveness in diffusing violent situations and reducing the use of force. Drawing on more than two decades of experience as a police officer and chief, TED Fellow Ivonne Roman shares how a simple change to police academy physical fitness tests could help build a more balanced force that benefits commu

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School segregation worsens for Latino children compared with a generation ago

Latino children are likely to enter elementary schools this year with fewer white peers than a generation ago, judging by data reported in a new study published today in Educational Researcher, a peer-reviewed journal of the American Educational Research Association. However, as racial segregation has intensified, low-income students of all racial groups are likely to learn beside more middle-clas

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Next-generation medication: Where chemistry meets computation

A group of Japanese researchers mainly from Tokyo University of Agriculture and Technology (TUAT) and Hokkaido University drastically enhanced and sped up the way to producing skeletally diverse indole alkaloids, composed of the medicinally-relevant scaffolds. By leveraging computational and synthetic approaches, this group has successfully developed a concise and versatile synthetic process gener

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Startups And Their Publications

How much does scientific publication matter? For once, we’re not going to be talking about its role in academia (partly because it obviously means quite a bit there!) No, how much does it matter in industry? Specifically, at highly valued biomedical startups? That’s the subject of this new paper by John Ioannides and co-authors, and I’ll go right to the conclusion: across 47 “unicorns”, startups

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Stem cell research sheds new light on the skin

For the first time, researchers have studied and outlined the development of sebaceous glands in the skin. The study provides greater insight into the development and maintenance of the skin and how cancer mutations affect the behavior of stem cells.

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Birthweight, height together provide insight into future heart health

It's the proportionately of a newborn — a measure that includes both birthweight and length — that may best tell doctors whether a child is born with an increased risk for heart problems later in life, investigators report.

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Scientists reproduce the dynamics behind astrophysical shocks

Article describes first laboratory measurement of the precursors to high-energy astronomical shocks.

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Tech companies not doing enough to protect users from phishing scams

Just over 15 years after the first reported incident of phishing, new research suggests tech companies could be doing more to protect users from the threat of scams. However, greater awareness of the issue is also needed among individuals and organizations.

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Starting with less-invasive procedures to restore leg blood flow as good at avoiding amputation as starting with open surgery

Patients who underwent a less-invasive procedure to open clogged leg arteries were just a likely to survive with their legs intact as patients who had more invasive surgery.

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Introduced species dilute the effects of evolution on diversity

An international research team has found that biodiversity is higher on older islands than on younger ones. Furthermore, they found that introduced species are diluting the effects of island age on patterns of local biodiversity.

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Predicting earthquake hazards from wastewater injection after fracking

Geoscientists develop a method to forecast seismic hazards caused by the disposal of wastewater after oil and gas production.

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Så rör sig enskilda hjärtmuskelproteiner

– Det är mycket viktigt att förstå detaljerna i hjärtats processer, säger Alf Månsson. Vid en rad sjukdomar, som hjärtsvikt och de genetiska sjukdomar i hjärtat som är den viktigaste orsaken till plötslig hjärtdöd hos unga, är de här processerna störda på olika sätt. Därför behöver vi veta hur de fungerar i normalläge. Forskare vid Linnéuniversitetet har samarbetat med forskare vid McGill-Univers

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China tech firm eyes IPO for gay dating app Grindr

The Chinese parent company of the popular gay dating app Grindr on Tuesday said it will "restart" plans for a public listing after a US national security panel dropped its opposition to the …

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TESS has found the first-ever ‘ultrahot Neptune’

NASA’s TESS telescope has spotted a world that could be a bridge between other types of exoplanets: hot Jupiters and scorched Earths.

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Bangladesh 'extremely worried' over low male tiger population

A lower-than-expected population of male Bengal tigers in the world's largest mangrove forest has sparked fears about the long-term viability of the endangered species in Bangladesh, officials said Tuesday.

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Bangladesh 'extremely worried' over low male tiger population

A lower-than-expected population of male Bengal tigers in the world's largest mangrove forest has sparked fears about the long-term viability of the endangered species in Bangladesh, officials said Tuesday.

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Dozens of live pangolins found hidden on bus in Vietnam

Dozens of live pangolins smuggled from Laos were discovered "dehydrated and weak" on a bus in central Vietnam, police and conservationists said Tuesday, in a country where the endangered mammals are a highly-prized delicacy.

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Ocean fizz could have helped to kick-start life

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02318-9 Microscopic bubbles can bring together biomolecules such as DNA.

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Green in cities gives mental health a boost

A new framework for how city planners can measure the mental health benefits of nature could help incorporate those benefits into plans and policies for cities and their residents. Almost one in five adults in the US lives with a mental illness. That statistic is similar worldwide, with an estimated 450 million people currently dealing with a mental or neurological disorder. Of those, only about

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Dozens of live pangolins found hidden on bus in Vietnam

Dozens of live pangolins smuggled from Laos were discovered "dehydrated and weak" on a bus in central Vietnam, police and conservationists said Tuesday, in a country where the endangered mammals are a highly-prized delicacy.

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Physicists Peer Inside a Fireball of Quantum Matter

A gold wedding band will melt at around 1,000 degrees Celsius and vaporize at about 2,800 degrees, but these changes are just the beginning of what can happen to matter. Crank up the temperature to trillions of degrees, and particles deep inside the atoms start to shift into new, non-atomic configurations. Physicists seek to map out these exotic states — which probably occurred during the Big Ban

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Report shows online behaviors concerning fidelity in relationships differ by age

Younger Americans could be putting their relationships at risk with looser relationship boundaries online, according to "iFidelity: The State of Our Unions 2019," a report from the National Marriage Project at the University of Virginia and the School of Family Life at Brigham Young University.

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Internationale forskere bekræfter: Radioaktiv sky kom fra russisk anlæg

Det er fortsat uopklaret, hvorfor en stor radioaktiv sky spredte sig over Europa i 2017. Men en ny videnskabelig artikel med blandt andet danske målinger mener at kunne identificere oprindelsen.

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Researchers report bio-inspired selective antibiotics

With multi-resistant germs becoming more and more of a threat, we are in need of new antibiotics now more than ever. Unfortunately, antibiotics cannot distinguish between pathogens and beneficial microbes. They can destroy the delicate balance of the microbiome—resulting in permanent damages. The research team of chemist Dr. Thomas Böttcher has now made a significant step towards solving these pro

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Smoking impedes embolization treatment in lungs

Smoking reduces the chances of a successful procedure to treat blood vessel abnormalities in the lungs, according to a new study.

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Researchers estimate societal costs of the opioid epidemic

The devastating consequences of the opioid crisis are far-reaching in the United States, impacting public health as well as social and economic welfare.

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What do quakes on Mars feel like?

Fifty years after Apollo 11 astronauts put the first seismometer on the surface of the Moon, data from NASA InSight’s seismic experiment gives researchers the chance to compare marsquakes to moon and earthquakes. Seismologists operating the Marsquake Service literally rocked and rolled as they experienced, for the first time, two marsquakes in the quake simulator at ETH Zurich. Researchers upload

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Tool, the long-time streaming service holdout, is finally relenting this week

Back in 2017, reports claimed that Tool had been talking to the big streaming services about making their music available to the companies, though nothing came of it. But the band has now confirmed …

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Learning in virtual spaces

Wuerzburg students of teacher training who like to try something new can look forward to the coming semesters. They will have the chance to try-out ViLeArn, a recently developed social-VR platform targeting virtual embodied teaching, during one of their seminars. ViLeArn allows students to dive into fully equipped virtual teaching environments with flexible layouts, which give ample room for vario

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3-D printable 2-D materials based inks show promise to improve energy storage devices

For the first time, a team of researchers, from the School of Materials and the National Graphene Institute at The the University of Manchester have formulated inks using the 2-D material MXene, to produce 3-D printed interdigitated electrodes.

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Researchers report bio-inspired selective antibiotics

With multi-resistant germs becoming more and more of a threat, we are in need of new antibiotics now more than ever. Unfortunately, antibiotics cannot distinguish between pathogens and beneficial microbes. They can destroy the delicate balance of the microbiome—resulting in permanent damages. The research team of chemist Dr. Thomas Böttcher has now made a significant step towards solving these pro

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Flat lenses with a twist

Overlaying two film layers patterned with a nanoscale array can manipulate the propagation of light to create a powerful ultrathin lens.

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How do Sherpas thrive up here?

New study suggests it’s something to do with their kidneys. Paul Biegler reports.

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Infants expect leaders to correct injustices

They learn early about social hierarchies and power dynamics, study suggests. Natalie Parletta reports.

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Could 'tickle' therapy help slow ageing?

UK study investigates the potential of vagus nerve stimulation. Nick Carne reports.

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EU-dom: Hjemmesider med en Facebook Like-knap gør sig til dataansvarlige

En EU-domstol har afsagt dom i et sagsanlæg mod virksomheden Fashion ID om brugen af Facebooks Like-knap, som ifølge dommen gør dem dataansvarlige for dataindsamling og -videresending.

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Harvard creates advisory panel to oversee solar geoengineering project

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02331-y Scientists will inject particles of calcium carbonate into the atmosphere and study their effects on incoming sunlight.

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Next step in producing magnetic organic molecules

A team has created new molecules with magnetic properties. In contrast to many earlier organic magnets, the molecules were stable in the presence of water and oxygen. Their magnetic properties were retained up to minus 110 degrees Celsius — which is relatively warm for these compounds.

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Non-lethal impacts of seabirds' plastic ingestion

A new study of seabirds that had ingested plastic debris has revealed a range of non-lethal impacts on their health and physiology. While seabird deaths due to swallowing plastic debris or becoming entangled in it have received global attention, the non-lethal effects on seabirds that survive plastic ingestion are less well-known.

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Smartphone virus scanner is not what you think

The current leading method to assess the presence of viruses and other biological markers of disease is effective but large and expensive. It is prohibitively difficult for use in many situations, especially due to certain economic and geographic factors. So researchers created and tested an alternative miniaturized system that makes use of low-cost components and a smartphone. Researchers hope th

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Cryptic variation in DNA can drive huge evolutionary leaps

Hidden, or “cryptic” variation in DNA, can lead to rapid leaps in evolution in ways that wouldn’t otherwise be possible, according to new research. Genetic variation—that is, accumulated mutations in the DNA—is the fuel for all evolutionary change: the more genetic variation, the faster evolution works and the more possibilities for novel adaptive solutions. But “cryptic” variation doesn’t alter

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Smartphone virus scanner is not what you think

The current leading method to assess the presence of viruses and other biological markers of disease is effective but large and expensive. It is prohibitively difficult for use in many situations, especially due to certain economic and geographic factors. So researchers created and tested an alternative miniaturized system that makes use of low-cost components and a smartphone. Researchers hope th

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Scientists Just Released a New Playbook for Engineering Longer, Healthier Lives

It’s hard to pinpoint the exact moment anti-aging research morphed from quackery to an established science. Some say it’s 1939, when an experiment that restricted calories in rodents bizarrely increased their lifespan. Others argue it’s 1961, when Leonard Hayflick discovered a limit for the number of times a human cell divides before it enters a dormant aged state. But perhaps the most disruptive

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Women's prisons: Why they do more harm than good

Sending women to prison, and removing them from their children and families, has long been seen as a contentious issue. Particularly given that women are predominately nonviolent offenders and tend to commit "victimless crimes"—such as theft—that are often survival based.

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Social spending on kids yields biggest bang for the buck

Investing in children's futures feels like the right thing to do, and now it turns out it's a really smart thing to do.

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Electrifying insights into how bodies form

At first glance, Mike Levin's lab looks like any standard biology lab with its shelves of petri dishes containing small, brown, semitransparent flatworms called planaria, one of the organisms his lab studies. Look more closely at the bodies of the tiny worms swimming and stretching under the plastic, however, and you might notice something strange—instead of a head and tail, each worm has two full

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African smoke is ‘fertilising the Amazon’

It may even have an impact in the Southern Ocean, new study finds.

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A nice view at ‘first light’

SPECULOOS shows that it’s ready for action.

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Stem cell research sheds new light on the skin

For the first time, researchers from the University of Copenhagen have studied and outlined the development of sebaceous glands in the skin. The study provides greater insight into the development and maintenance of the skin and how cancer mutations affect the behavior of stem cells.

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Electrifying insights into how bodies form

At first glance, Mike Levin's lab looks like any standard biology lab with its shelves of petri dishes containing small, brown, semitransparent flatworms called planaria, one of the organisms his lab studies. Look more closely at the bodies of the tiny worms swimming and stretching under the plastic, however, and you might notice something strange—instead of a head and tail, each worm has two full

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Gatekeepers of the genome

Transcription factors control gene activation in cells. By binding to specific segments of DNA, they enable the blueprints that code for cellular proteins to be produced. But how are such factors themselves regulated?

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Seabirds' cholesterol levels raised through plastic ingestion

A new study of seabirds that had ingested plastic debris has revealed the range of impacts on their health and physiology including a rise in cholesterol levels.

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Bone tissue engineering—nano-glue polymer membranes for robust bone regeneration

In a new study now published on NPG Asia Materials, bioengineers report the development of a new fibrous membrane with stem cells to repair bone defects in the skulls of mice. For this, they incorporated mussel-inspired polydopamine protein as a promising compound to tether biological substances to the membrane surfaces, much like adhesive proteins in mussels. In the work, Yi Deng and a research t

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Next step in producing magnetic organic molecules

A team from the Ruhr Explores Solvation Cluster of Excellence at Ruhr-Universität Bochum has created new molecules with magnetic properties. In contrast to many earlier organic magnets, the molecules were stable in the presence of water and oxygen. Their magnetic properties were retained up to minus 110 degrees Celsius—which is relatively warm for these compounds. Together with colleagues from the

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People of color support climate action, but few get credit for it

Looking at climate change action campaigns and media coverage in the United States, one might get the idea that only white, upper-middle-class people are concerned about the environment.

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New Research: Every Transistor Has a “Unique Quantum Fingerprint”

Quantum Fingerprint Take an extremely powerful microscope to a transistor , and you’ll see minuscule defects that alter the flow of electricity. These defects can disrupt electricity at the scale of a single electron, according to research published this month in the journal Applied Physics Letters . Though no hardware currently exploits this so-called single electron effect, Phys.org reports tha

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Voters weren’t choosing ‘momentum’ in 2016 primaries

Voters chose their favorite candidates, not those with “momentum,” in the 2016 presidential primaries, research suggests. One of the many stories to emerge from that raucous primary season centered on the concept of momentum: who had it, who didn’t, and what it all meant for primary outcomes. If voters shifted their votes as a result of earlier primaries, could the party’s nomination have gone to

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Gatekeepers of the genome

Transcription factors control gene activation in cells. By binding to specific segments of DNA, they enable the blueprints that code for cellular proteins to be produced. But how are such factors themselves regulated?

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The surprising link between a babies' weeble-wobble and the genetics of motor control

Neuroscientists at the University of Sussex have revealed that complex movements, such as those that maintain our posture, can be controlled by a simple genetic system, providing a framework to better understand the molecular basis of diseases that affect motor control, like Huntington's and Parkinson's.

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Cigarette smoke makes MRSA superbug bacterium more drug-resistant

Cigarette smoke can make MRSA bacterial strains more resistant to antibiotics, new research from the University of Bath has shown.

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Virtual reality to solve personal problems

A new study published in the Nature Group's journal Scientific Reports shows that conversation with oneself embodied as Dr. Sigmund Freud works better to improve people's mood, compared to just talking about your problems in a virtual conversation with pre-scripted comments. Researchers claimed that the method could be used by clinicians to help people dealing with minor personal problems.

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Girls who are more physically active in childhood may have better lung function in adolescence

A study of more than 2,300 adolescents underscores the pulmonary health benefits of physical activity.

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New method increases accuracy of nontuberculous mycobacteria identification

The more than 200 species of nontuberculous mycobacteria (NTM) are notoriously difficult to differentiate, delaying the implementation of targeted antibiotic therapy. Researchers from Osaka University and the University of the Ryukyus in Japan have now developed a comprehensive database of 175 NTM species based on new and existing genome sequences, along with specialized comparative software, that

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Next step in producing magnetic organic molecules

A team from the Ruhr Explores Solvation Cluster of Excellence at Ruhr-Universität Bochum has created new molecules with magnetic properties. In contrast to many earlier organic magnets, the molecules were stable in the presence of water and oxygen. Their magnetic properties were retained up to minus 110 degrees Celsius — which is relatively warm for these compounds.

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Smartphone virus scanner is not what you think

The current leading method to assess the presence of viruses and other biological markers of disease is effective but large and expensive. It is prohibitively difficult for use in many situations, especially due to certain economic and geographic factors. So researchers created and tested an alternative miniaturized system that makes use of low-cost components and a smartphone. Researchers hope th

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How temp makes some drugs separate like salad dressing

A new mathematical model describes how highly concentrated antibody solutions separate into different phases, similar to an oil and water mixture. This separation can reduce the stability and shelf-life of some drugs that use monoclonal antibodies, including some used to treat autoimmune diseases and cancer. Scientists from Penn State and MedImmune, LLC (now AstraZeneca) investigated the thermody

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National Service Is a Terrible Idea

The Democratic presidential candidate John Delaney proposed this week that the government partner with private companies and unions to create a national program of forced labor. He calls it “ John Delaney’s Plan for National Service .” “Every American will complete a minimum of 1 year and a maximum of 2 years of mandatory national service when they graduate high school, or turn 18,” it states. “N

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Meet a 500-million-year old minibeast from the Cambrian explosion

More than half a billion years ago, this predator cruised the seas in what is now Yunnan, China. The remarkable fossil is on display in a new exhibition

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Retired Astronaut: Sending a Woman to the Moon “Sounds Like a Stunt”

Equal Opportunity In March, NASA administrator Jim Bridenstine said during a talk show appearance that the next person on the Moon is “likely to be a women.” Now, retired NASA astronaut and former International Space Station commander Peggy Whitson is rebuking NASA’s plan, saying she doesn’t think gender should have anything to do with the Moonwalker decision. Earned Honor In a recent interview w

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Researchers model unihemispheric sleep in humans

Some animals, such as birds, dolphins, and whales, can engage in unihemispheric sleep, in which one hemisphere of the brain sleeps while the other hemisphere remains awake. Staying half-awake allows animals to literally "keep an eye open" for predators, and for migrating birds, allows for uninterrupted flight for days or even weeks on end.

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Conservation or construction? Deciding waterbird hotspots

Imagine your favorite beach filled with thousands of ducks and gulls. Now envision coming back a week later and finding condos being constructed on that spot. This many ducks in one place surely should indicate this spot is exceptionally good for birds and must be protected from development, right?

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Small, nimble CSU satellite has surpassed a year in space

After meeting all its benchmarks for demonstrating small-satellite weather forecasting capabilities during its first 90 days, a Colorado State University experimental satellite is operating after more than one year in low-Earth orbit.

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A novel peptide to rapidly kill multidrug-resistant bacteria

Researchers at the Indian Institute of Science (IISc) have designed an antimicrobial peptide (AMP) that can effectively and quickly kill a notorious multidrug-resistant bacterium called Acinetobacter baumannii.

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Is Recovery the Key to Optimal Performance?

Get-Fit Guy interviews Will Ahmed, CEO of a recovery device called WHOOP, to examine and quantify sleep, recovery, and strain — Read more on ScientificAmerican.com

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A novel peptide to rapidly kill multidrug-resistant bacteria

Researchers at the Indian Institute of Science (IISc) have designed an antimicrobial peptide (AMP) that can effectively and quickly kill a notorious multidrug-resistant bacterium called Acinetobacter baumannii.

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Conservation or construction? Deciding waterbird hotspots

Imagine your favorite beach filled with thousands of ducks and gulls. Now envision coming back a week later and finding condos being constructed on that spot. This many ducks in one place surely should indicate this spot is exceptionally good for birds and must be protected from development, right?

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Smartphone virus scanner: New portable device lets smartphones count biological viruses

The current leading method to assess the presence of viruses and other biological markers of disease is effective but large and expensive. It is prohibitively difficult for use in many situations, especially due to certain economic and geographic factors. So researchers created and tested an alternative miniaturized system that makes use of low-cost components and a smartphone. Researchers hope th

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Next-generation medication: where chemistry meets computation

A group of Japanese researchers drastically enhanced and sped up the way to skeletally diverse indole alkaloids, composed of the medicinally-relevant scaffolds. By leveraging computational and synthetic approaches, this group has successfully developed a concise and versatile synthetic process generating the densely-functionalized multicyclic complex scaffolds, which would facilitate the developme

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Researchers repair faulty brain circuits using nanotechnology

Working with mouse and human tissue, Johns Hopkins Medicine researchers report new evidence that a protein pumped out of some — but not all — populations of 'helper' cells in the brain, called astrocytes, plays a specific role in directing the formation of connections among neurons needed for learning and forming new memories.

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Adjuvant radiotherapy may be beneficial in treating locally advanced prostate cancer

Adjuvant radiotherapy administered after surgical removal of the prostate prolongs disease-free time as measured by PSA, a Finnish study shows.

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New nanoparticle combination therapy shows effective resuscitation for massive hemorrhage

Japanese scientists successfully resuscitated rabbits with coagulopathy from severe hemorrhagic shock using hemostatic nanoparticles and oxygen-carrying nanoparticles, which respectively stopped bleeding and delivered oxygen to the systemic tissues and organs. There are no effective therapies for such massive hemorrhage so far, thereby the combination therapy using two kinds of functional nanopart

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School segregation worsens for Latino children compared with a generation ago

Latino children are likely to enter elementary schools this year with fewer white peers than a generation ago, judging by data reported in a new study published today in Educational Researcher, a peer-reviewed journal of the American Educational Research Association. However, as racial segregation has intensified, low-income students of all racial groups are likely to learn beside more middle-clas

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Researchers estimate societal costs of the opioid epidemic

The devastating consequences of the opioid crisis are far-reaching in the United States, impacting public health as well as social and economic welfare. Penn State researchers recently collaborated to address the issue in a supplement of The American Journal of Managed Care titled 'Deaths, Dollars, and Diverted Resources: Examining the Heavy Price of the Opioid Epidemic.'

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Decoding the complex life of a simple parasite

Scientists decode the genome sequence of one of nature's most complex parasites, dicyemids.

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New study reveals how TB bacteria may survive in human tissues

Associate Professor Chris Greening and his team of microbiologists from the School of Biological Sciences, Monash University, have discovered that some pathogens depend on carbon monoxide to survive when other nutrients are not available.

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Waze makes it easier for Carpool drivers to invite multiple riders

Waze's Carpool service is all about adding more passengers to save money on your commute, so wouldn't it make sense to invite multiple riders in one go? You can now. Waze …

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NASA’s TESS Spots 3 New Exoplanets in Rare Solar System

The Kepler planet-hunting satellite is long gone, but NASA’s Transiting Exoplanet Survey Satellite (TESS) is just getting started. This satellite has spotted a few exoplanets early in its mission, and the most recent batch includes some extremely weird worlds along with yet another super-Earth. The super-Earth is scorching hot, and the others are cooler. However, they’re not ice worlds like Neptu

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NASA Tests Mars 2020 Robotic Arm With ‘Biceps Curls’

Slowly but surely, the Mars 2020 rover is taking shape at NASA’s Jet Propulsion Laboratory (JPL). Engineers have attached some of the rover’s many cameras , its wheels , and now it’s time to give its robotic arm a test run . This arm will have to do some heavy lifting on the red planet, so NASA is having it do some biceps curls on Earth. It’s actually studying how the rover will maneuver its heft

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Decoding the complex life of a simple parasite

Dicyemids, microscopic parasites comprising 30 cells, are in-between creatures. With their basic three-part body plan, they are more complex than single-celled protozoans but considerably less complex than multicellular metazoans—the animals of the kingdom Animalia. Yet the simple makeup of these so-called mesozoans does not translate to a simple life.

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New method increases accuracy of nontuberculous mycobacteria identification

The bacterial genus Mycobacterium has the dubious honor of including species responsible for two of the best-known chronic human infectious diseases: tuberculosis and leprosy. But unlike their more famous cousins, for which effective treatment strategies have long been available, it is the 200 or so lesser known Mycobacterium species that are currently causing a resurgence in pulmonary diseases in

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Decoding the complex life of a simple parasite

Dicyemids, microscopic parasites comprising 30 cells, are in-between creatures. With their basic three-part body plan, they are more complex than single-celled protozoans but considerably less complex than multicellular metazoans—the animals of the kingdom Animalia. Yet the simple makeup of these so-called mesozoans does not translate to a simple life.

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New method increases accuracy of nontuberculous mycobacteria identification

The bacterial genus Mycobacterium has the dubious honor of including species responsible for two of the best-known chronic human infectious diseases: tuberculosis and leprosy. But unlike their more famous cousins, for which effective treatment strategies have long been available, it is the 200 or so lesser known Mycobacterium species that are currently causing a resurgence in pulmonary diseases in

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Ghana 'exports rosewood timber illegally to China'

Corrupt officials are forging documents to allow the wood to leave the country, environmentalists say.

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Making conductors stretchable by using multiple layers arranged in a gradient

A team of researchers affiliated with several institutions in the Republic of Korea and the U.S. has developed a means for creating a new kind of stretchable conductor. In their paper published in the journal Science Advances, the group describes their process and the conductors they made, and the results of testing with a battery.

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Migrants in rural areas face particular challenges

Jobs on EU farms are increasingly being filled by migrants who help to cultivate some of our most common kitchen staples. But migrants who move to rural areas also face additional difficulties than people who choose to migrate to the EU and settle in towns and cities. These findings are the result of the first EU-wide statistical analysis of migrants living in rural areas.

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Belligerent beetles show that fighting for mates could help animals survive habitat loss

Animals around the world are seeing their environments change. Climate change is causing heating and changes to weather patterns, the oceans are becoming more acidic, and previously undisturbed habitats are being altered and degraded by human activities.

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Research aims to preserve the future of Ningaloo Reef corals

Researchers at The University of Western Australia are a step closer to discovering more about the health of our oceans after analyzing how coral in Ningaloo Reef formed.

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Belligerent beetles show that fighting for mates could help animals survive habitat loss

Animals around the world are seeing their environments change. Climate change is causing heating and changes to weather patterns, the oceans are becoming more acidic, and previously undisturbed habitats are being altered and degraded by human activities.

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Research aims to preserve the future of Ningaloo Reef corals

Researchers at The University of Western Australia are a step closer to discovering more about the health of our oceans after analyzing how coral in Ningaloo Reef formed.

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An Electric Pickup Truck Really Could Pull a Freight Train—Here's How

Ford showed off an all-electric F-150 pickup truck towing a freight train full of more F-150s. The stunt relies heavily on one force to work: friction.

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The World Is Complex. Measuring Charity Has to Be Too

Single-serving metrics are attractive, but they miss the big complicated messy picture.

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From the archive

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02309-w How Nature reported plans to exploit Australia’s natural resources in 1919, and to develop computers as teaching aids in 1969.

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"Wild Hearts" by Cathy Dennis | Serengeti (Music Video)

Performed by: Cathy Dennis Written by: Cathy Dennis Written, Composed & Produced by: Will Gregory SERENGETI premieres Aug 4 at 8P ET only on Discovery Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Join us on Facebook: http://www.facebook.com/Serengeti https://www.facebook.com/Discovery Follow us on Twitter: https://twitter.com/Discovery From: Discovery

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Study shows non-lethal impacts of seabirds' plastic ingestion

An IMAS-led study of seabirds that had ingested plastic debris has revealed a range of non-lethal impacts on their health and physiology. While seabird deaths due to swallowing plastic debris or becoming entangled in it have received global attention, the non-lethal effects on seabirds that survive plastic ingestion are less well-known.

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3D printed rocket fuel comparison at James Cook University

James Cook University scientists in Australia are using 3D printing to create fuels for rockets, and using tailor-made rocket motors they've built to test the fuels.

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Analysis reveals economic cost of Alzheimer's disease and dementia are 'tip of the iceberg'

A new research review highlighting the hidden costs of dementia suggests that traditional measures only show the 'tip of the iceberg' of the cost impact on society.

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Stressed at school? Art therapy reduces teenage girls' headaches

In a pilot study led by the UW, researchers explored art-based mindfulness activities that schools could use to reduce headaches, a common side effect of stress in adolescent girls. After three weeks of twice-weekly mindfulness and art therapy sessions, 8 teenage girls reported experiencing significantly fewer headaches.

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Ultra-thin layers of rust generate electricity from flowing water

Tom Miller of Caltech and Franz Geiger of Northwestern University show that iron oxide layers can convert kinetic energy of saltwater into electrical power.

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PSR J2055+3829 is an eclipsing 'black widow' pulsar, study finds

By conducting timing observations, astronomers have uncovered important insights into the properties of the millisecond pulsar PSR J2055+3829. Results of the observations, presented in a paper published July 23 on arXiv.org, indicate that this object is an eclipsing "black widow" pulsar.

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Researchers develop novel process for structuring quantum materials

Implementing quantum materials in computer chips provides access to fundamentally new technologies. To build high-performance quantum computers, for example, topological insulators have to be combined with superconductors. This fabrication step is associated with a number of challenges that have now been solved by researchers from Jülich. Their results are presented in the current issue of the jou

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Non-contact photogrammetric system to capture digital image of Ignatievka Cave

Scientists of South Ural State University have engineered a unique photogrammetric system for high-precision, noncontact measurements of 3-D coordinates, which can create 3-D models of ancient cultural monuments. The researchers plan to use this system in archaeological studies of Ignatievka Cave, located in the southern Ural Mountains, where cave drawings were found in 1980.

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Analyzing gravity waves at the edge of space

Jeff Forbes is working on a research project slated for the International Space Station (ISS) to help us better understand and forecast conditions on the edge of space.

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Cheops passes final review before shipment to launch site

The Characterising Exoplanet Satellite, Cheops, has successfully passed the final analysis review for its launch on a Soyuz rocket from Europe's Spaceport in Kourou, French Guiana.

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First rollout of Ariane 6 mobile gantry

At Europe's Spaceport the Ariane 6 mobile gantry, a 90 metre-high metallic structure built to house Ariane 6 underwent a 97 m rollout test last week to mimic prelaunch.

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Study: People may use overconfidence to persuade or deceive others

A pair of researchers, one from the University of Munich, the other the University of Amsterdam has found that people may behave with overconfidence as a means to persuade or deceive other people. In their paper published in the journal Nature Human Behavior, Peter Schwardmann and Joël van der Weele describe a two-stage experiment they carried out with volunteers and what they found.

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Weight stigma in men associated with harmful health consequences

As many as 40% of men report experiencing weight stigma, but little is known about how this stigma affects their health. This study found that men experiencing weight stigma have more depressive symptoms, are more likely to binge eat, and have lower self rated health.

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Boom i mobile atomreaktorer skaber frygt hos norsk atomberedskab

PLUS. 33 år efter Tjernobyl-ulykken har atomtruslen ændret sig. Der kommer flere mobile atomreaktorer langs den norske kyst, og det stiller nye krav til målinger og beredskab.

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Study suggests frozen Earthlike planets could support life

Icy planets once thought too cold to support life might have livable land areas above freezing, challenging the typical assumption of what kinds of planets might be habitable, a new study suggests.

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Research identifies the SIGN-R1 molecule responsible for influenza virus recognition

A team of researchers from the Institute for Research in Biomedicine (IRB, affiliated to USI Università della Svizzera italiana, Switzerland) have discovered and identified a molecule—SIGN-R1—capable of recognizing the multiple variants of influenza and consequently 'directing' the immune response in individuals affected by the disease. The results of the research, which pave the way for the desig

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The way that minerals are mined affects conflict in eastern Congo

Strong evidence links the mining of minerals to local conflict in several African countries. This is because minerals are prized by rebel groups and are a source of their financing. Examples include the "blood diamonds" that were used to finance armed groups in Sierra Leone and Liberia. But existing research makes no distinction on how the two main types of mineral extraction—artisanal and industr

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Why Kids Invent Imaginary Friends

On a recent Monday morning, 10-year-old Sasha told her mother about the current drama between her two best friends. Tentacles, a giant Pacific octopus, had told Sasha that he was in love with Coral, who is also an octopus, but who has “one extra tentacle that she’s learning how to use,” per Sasha. Coral was unaware of Tentacles’ infatuation, but had relayed a similar message to Sasha: She had str

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Research identifies the SIGN-R1 molecule responsible for influenza virus recognition

A team of researchers from the Institute for Research in Biomedicine (IRB, affiliated to USI Università della Svizzera italiana, Switzerland) have discovered and identified a molecule—SIGN-R1—capable of recognizing the multiple variants of influenza and consequently 'directing' the immune response in individuals affected by the disease. The results of the research, which pave the way for the desig

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Sony has sold 100 million PS4 consoles

After nearly six years on the market, the PlayStation 4 is still going strong.

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Små fält och olika grödor ger mångfald i jordbrukslandskapet

– Små fält ses ofta som ett hinder för ett rationellt jordbruk, eftersom de kan ge högre kostnader per hektar åkermark, men vi ser att de verkligen kan vara en nyckel för att bevara den biologiska mångfalden. Jag hoppas att våra resultat kan bidra till att tillvarata de värden som finns i småskaliga jordbrukslandskap, säger Yann Clough, professor i miljövetenskap på Centrum för miljö- och klimatf

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We can't expand airports after declaring a climate emergency – let's shift to low-carbon transport instead

The world may finally be waking to the reality of the climate and ecological crisis after 30 years of inaction. But while the UK government has declared a climate and ecological emergency, ongoing plans for airport expansions suggest we're flying full-speed towards crisis rather than away from it.

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Image of the Day: Mosquito Flight Simulator

Carbon dioxide pumped into a bright chamber mimics a breathing host for the pest to target.

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Unagi Model One Review: A Light and Portable Urban Scooter

As long as the roads aren’t too bad, Unagi’s electric ride can help keep your car in the garage until you truly need it.

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New strategies for optimizing the specificity of gene editing nucleases

Sangamo Therapeutics, Inc., a genomic medicine company, announced today the publication in Nature Biotechnology of a manuscript by Jeffrey Miller, Ph.D., and colleagues at Sangamo, describing two new strategies for optimizing the specificity of genome editing using zinc finger nucleases (ZFNs). The ability to engineer highly specific gene editing nucleases with little or no detectable activity at

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'Unprecedented' discovery of unique infrared light signature on Neptune's moon Triton

Triton orbits Neptune, the eighth planet from the Sun, some 2.7 billion miles from Earth—at the cold outer fringe of the Solar System's major planet zone. Surface temperatures hover near absolute zero, so low that common compounds we know as gases on Earth freeze into ices. Triton's atmosphere, which is 70,000 times less dense than Earth's, is composed of nitrogen, methane and carbon monoxide.

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New study reveals how TB bacteria may survive in human tissues

Carbon monoxide is an infamous and silent killer that can cause death in minutes. But while it is deadly for us, some microorganisms actually thrive on it, by using this gas as an energy source.

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Ultra-thin layers of rust generate electricity from flowing water

There are many ways to generate electricity—batteries, solar panels, wind turbines, and hydroelectric dams, to name a few examples… and now, there's rust.

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Scientists use isotopes to reveal how aquifer refilled 400,000 years ago

The Negev desert, which covers half of Israel's land mass, is so dry that parts of it get less than three inches of water a year. But beneath it is water that sustains the people and agriculture of the region. Understanding where it came from, how much is there, and what's happening to it is critical to the security and allocation of that crucial resource.

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New strategies for optimizing the specificity of gene editing nucleases

Sangamo Therapeutics, Inc., a genomic medicine company, announced today the publication in Nature Biotechnology of a manuscript by Jeffrey Miller, Ph.D., and colleagues at Sangamo, describing two new strategies for optimizing the specificity of genome editing using zinc finger nucleases (ZFNs). The ability to engineer highly specific gene editing nucleases with little or no detectable activity at

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New study reveals how TB bacteria may survive in human tissues

Carbon monoxide is an infamous and silent killer that can cause death in minutes. But while it is deadly for us, some microorganisms actually thrive on it, by using this gas as an energy source.

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Environmental ingenuity: These creative business ideas aim to be both sustainable and successful

Picture this: Out in the open ocean, rows of farmed kelp spanning an area about the size of Mexico. Once harvested and processed, this rapid-growing seaweed would be turned into a fuel that you could pump into your car. No more relying on fossil fuels that take millions of years to form—and whose emissions into the atmosphere are the biggest contributor to the Earth's rising temperatures.

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Lights out: putting the ambient air oxidation of monolayer tungsten disulphide to bed

To protect monolayer semiconductor transition metal dichalcogenides (S-TMDs) from oxidation, they must be entirely shielded from light, with even short exposure causing oxidation severe enough to damage electrical contacts and completely destroy optical characteristics.

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The Challenge of Deepfakes

You have probably heard of deepfakes by now – convincing video manipulation that is improving rapidly, getting better and easier. Right now you can often tell when a video has been manipulated. The human eye is very sensitive to movement, facial expressions, and other subtle cues. But the best examples are getting more difficult, and experts predict there will be deepfakes undetectable by most pe

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Sophie the robot whips up oodles of Singapore noodles

submitted by /u/gone_his_own_way [link] [comments]

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The benefits of using metal straws

submitted by /u/gimpnax [link] [comments]

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Deeper wells won’t solve America’s groundwater problem

People are drilling deeper wells to find water, according to the first comprehensive account of groundwater wells across the contiguous United States. Groundwater may be out of sight, but for over 100 million Americans who rely on it for their lives and livelihoods it’s anything but out of mind. Unfortunately, wells are going dry and scientists are just beginning to understand the complex landsca

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Life, Liberty and the Pursuit of Science

Two high school students argue that STEM knowledge and skills are vital to maintaining democracy — Read more on ScientificAmerican.com

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Better communication helps cancer patients feel ‘in control’

Working on the communication between physicians and their patients can improve care for people living with cancer, according to a new study. Sharon Licqurish, a research fellow at Monash University Nursing and Midwifery, and Jon Emery, a professor of primary care cancer research and director of the Primary Care Collaborative Cancer Clinical Trials Group at the Centre for Cancer Research at the Un

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Alarming surge in drug-resistant HIV uncovered

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02316-x The drug-resistant form of the virus has been detected at unacceptable levels across Africa, Asia and the Americas.

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Life, Liberty and the Pursuit of Science

Two high school students argue that STEM knowledge and skills are vital to maintaining democracy — Read more on ScientificAmerican.com

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Met Office confirms highest temperature ever recorded in the UK

The 38.7°C recorded in Cambridge Botanic Garden on 25 July has now been confirmed to be the highest temperature ever recorded in the UK

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How valuable is financial aid to low-income students?

In the 2015-16 academic year, students received $28 billion in Federal Pell Grants. The monetary assistance helps students who display exceptional financial need pay for their tuition. But more than the dollar amount is how that aid helps college students shape the rest of their lives.

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How humans and chimpanzees travel towards a goal in rainforests

How do human-unique ranging styles, like large home range and trail use, influence the way we travel to our goals? Researchers from the Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, investigated spatial movement patterns of the Mbendjele BaYaka people and Taï chimpanzees. Human foragers and chimpanzees traveled in similarly straight lines towards goals, but they showed clea

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How humans and chimpanzees travel towards a goal in rainforests

How do human-unique ranging styles, like large home range and trail use, influence the way we travel to our goals? Researchers from the Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, investigated spatial movement patterns of the Mbendjele BaYaka people and Taï chimpanzees. Human foragers and chimpanzees traveled in similarly straight lines towards goals, but they showed clea

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Three pitfalls to avoid in machine learning

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02307-y As scientists from myriad fields rush to perform algorithmic analyses, Google’s Patrick Riley calls for clear standards in research and reporting.

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Scientists call for modernization of EU gene-editing legislation

When using conventional methods, it usually takes relatively long to breed new plant varieties with favourable characteristics. On the other hand, precision breeding with genetic scissors such as CRISPR-Cas can significantly accelerate this process. However, the current interpretation of the European legislation prevents the use of genome editing in the European Union. European scientists are now

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Removing carbon dioxide from power plant exhaust

Reducing carbon dioxide (CO2) emissions from power plants is widely considered an essential component of any climate change mitigation plan. Many research efforts focus on developing and deploying carbon capture and sequestration (CCS) systems to keep CO2 emissions from power plants out of the atmosphere. But separating the captured CO2 and converting it back into a gas that can be stored can cons

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Health effects of China's climate policy extend across Pacific

Improved air quality can be a major bonus of climate mitigation policies aimed at reducing greenhouse gas emissions. By cutting air pollution levels in the country where emissions are produced, such policies can avoid significant numbers of premature deaths. But other nations downwind from the host country may also benefit.

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The Mesoamerican attraction to magnetism

The purpose of Mesoamerican potbelly statues have been the subject of debate among anthropologists for decades: Are they depictions of the ruling elite? A way to honor dead ancestors? Or perhaps portrayals of women giving birth?

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Scientists call for modernization of EU gene-editing legislation

When using conventional methods, it usually takes relatively long to breed new plant varieties with favourable characteristics. On the other hand, precision breeding with genetic scissors such as CRISPR-Cas can significantly accelerate this process. However, the current interpretation of the European legislation prevents the use of genome editing in the European Union. European scientists are now

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Strap on Your Exoskeleton and Dance, Dance, Dance

At San Francisco's Gray Area Festival, attendees immerse themselves in art and technology—and even surrender control of their bodies to robots.

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Now Even Funerals Are Livestreamed—and Families Are Grateful

With friends and relatives dispersed, a growing number of funeral homes will stream services, and demand is increasing.

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Google's New Gesture Controls Aren't Just for the Pixel

The Pixel 4 smartphone is being built to house a chip called Soli that could eventually power gesture-based user interfaces in everything from VR headsets to cars.

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Thanks to science, parasite can have sex in mice, not just cats

Toxoplasma gondii, a single-celled parasite perhaps best known for its ability to trick mice into taking potentially fatal risks around cats and, in humans, as a serious threat to fetal health, has given up a long-held secret of its reproduction.

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Glaciologists unveil most precise map ever of Antarctic ice velocity

Constructed from a quarter century's worth of satellite data, a new map of Antarctic ice velocity by glaciologists from the University of California, Irvine and NASA's Jet Propulsion Laboratory is the most precise ever created.

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Thanks to science, parasite can have sex in mice, not just cats

Toxoplasma gondii, a single-celled parasite perhaps best known for its ability to trick mice into taking potentially fatal risks around cats and, in humans, as a serious threat to fetal health, has given up a long-held secret of its reproduction.

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Spanish slugs: Moscow alarm over giant invasive pests

Voracious Arion vulgaris slugs have spread across Europe from Spain and are major pests.

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Genetic testing: What secrets could it reveal about you?

Genome sequencing projects around the world are revealing promising new health insights.

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India tiger census shows rapid population growth

PM Narendra Modi says India is "now one of the biggest and most secure habitats of the tiger".

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Epic 'Terminator' Events Could Result in Gargantuan Solar Tsunamis, New Studies Suggest

What causes the sun's 11-year cycle of sunspot activity? According to two new studies, it could be literal tsunamis of plasma.

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'Living Snow' of Grasshoppers Blankets Las Vegas, Visible on Radar

Swarms of grasshoppers resembled fabled plagues of biblical proportions.

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Iron Age Celtic Woman Wearing Fancy Clothes Buried in This 'Tree Coffin' in Switzerland

She was about 40 when she died and performed very little physical labor in life.

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Testosterone Therapy Can Restore Women's Libido–but Questions Remain

Although the hormone has few serious short-term side effects, its long-term risks remain a black box — Read more on ScientificAmerican.com

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Huawei reports revenue surge despite US ban – CNET

The Chinese phonemaker said its revenue grew more than 23% in the first half of 2019.

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Meet the African researcher who is building a core of junior immunologists on the continent

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02334-9 Faith Osier discusses a bold plan to increase African representation in the global research community.

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Testosterone Therapy Can Restore Women's Libido–but Questions Remain

Although the hormone has few serious short-term side effects, its long-term risks remain a black box — Read more on ScientificAmerican.com

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Democrats Hear the ‘Yes in My Backyard’ Message

Last week, Amy Klobuchar became the latest Democratic presidential hopeful to say out loud that cities and towns need to let people build more housing. She joined Cory Booker, Julián Castro, and Elizabeth Warren in proposing a more active federal role in getting state and local governments to loosen zoning rules—a topic that, up to now, has not figured prominently in campaigns for the White House

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What proof is there that the universe is evolving?

Light moves at 186,000 miles per second. As fast as light speed is, when you think about how large the universe is, light takes time — a lot of time — to actually get to us from distant objects. The sun is about 93 million miles away. At 186,000 miles per second, it takes about eight minutes for its light to reach us here on Earth. Because of this, when you look up at the sun, with eye protection

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Trump Makes Clear What Black Voters Had to Lose

Updated on July 30 at 9:32 a.m. ET In late summer 2016, the Republican presidential candidate Donald Trump embarked on what he claimed was an appeal to African American voters. In August, Trump traveled to Michigan for an event that was part of the push, though reporters noted that his speech was actually given in a predominantly white suburb of Lansing . “What the hell do you have to lose?” Trum

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The Life-Changing Magic of Tripping

Mark Kleiman, a professor at New York University who was one of the nation’s most respected scholars of criminal (and especially drug) policy, died last week after a kidney transplant from his sister Kelly failed to take. As one of the many journalists whose work was improved by Kleiman’s ideas (this September 2010 Atlantic feature on alternatives to prison was inspired by his book When Brute For

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New material could make it easier to remove colon polyps

MIT researchers have developed a gel that can be injected into the tissue lining the colon, forming a 'cushion' that makes it easier to remove precancerous polyps during a colonoscopy.

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Authors object as “doubtful” data doom dermatology paper

A dermatology journal has retracted a 2017 article by a pair of researchers in Saudi Arabia after receiving a “serious complaint” about the integrity of the data. But the first author of the paper pushed back, saying the move was unjustified. The article, “Successful use of combined corticosteroids and rituximab in a patient with refractory … Continue reading

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Reusing Wastewater for Crops Could Reduce Water Scarcity, If We Can Stomach It.

Recycling wastewater for use in agriculture could cut down on pollution of waterways and slow the rate at which food production depletes freshwater. But beyond practical considerations of risks and benefits, recycling wastewater has an inherent “yuck factor” to be overcome before it can be adopted at scale.

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Debate over the universe’s expansion rate may unravel physics. Is it a crisis?

Measurements of the Hubble constant don’t line up. Scientists debate what that means.

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Look beyond the lab for collectors of reusable data

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02328-7

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Keeping up Africa’s science momentum

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02326-9

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Julia: come for the syntax, stay for the speed

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02310-3 Researchers often find themselves coding algorithms in one programming language, only to have to rewrite them in a faster one. An up-and-coming language could be the answer.

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A new World Heritage site for Aboriginal engineering

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02315-y

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In-depth approach to river restoration

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02327-8

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A notable centenary for international science

Nature, Published online: 30 July 2019; doi:10.1038/d41586-019-02325-w

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Ministerium blev advaret om dårlig sikkerhed i system til vælgererklæringer for flere år siden

En it-sikkerhedsekspert advarede om mangelfuld sikkerhed i det digitale system til vælgererklæringer allerede i 2016, hvor systemet var nyindført.

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How humans and chimpanzees travel towards a goal in rainforests

How do human-unique ranging styles, like large home range and trail use, influence the way we travel to our goals? Researchers from the Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, investigated spatial movement patterns of the Mbendjele BaYaka people and Taï chimpanzees. Human foragers and chimpanzees travelled in similarly straight lines towards goals, but they showed cle

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Starting with less-invasive procedures to restore leg blood flow as good at avoiding amputation as starting with open surgery

Patients who underwent a less-invasive procedure to open clogged leg arteries were just a likely to survive with their legs intact as patients who had more invasive surgery.

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Systemic arterial hypertension leads to decreased semen quality and alterations in the testicular microcirculation in rats

Scientific Reports, Published online: 30 July 2019; doi:10.1038/s41598-019-47157-w

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Thermodynamic Stability and Structural Insights for CH3NH3Pb1−xSixI3, CH3NH3Pb1−xGexI3, and CH3NH3Pb1−xSnxI3 Hybrid Perovskite Alloys: A Statistical Approach from First Principles Calculations

Scientific Reports, Published online: 30 July 2019; doi:10.1038/s41598-019-47192-7 Thermodynamic Stability and Structural Insights for CH 3 NH 3 Pb 1−x Si x I 3 , CH 3 NH 3 Pb 1−x Ge x I 3 , and CH 3 NH 3 Pb 1−x Sn x I 3 Hybrid Perovskite Alloys: A Statistical Approach from First Principles Calculations

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When a Mega-Tsunami Drowned Mars, This Spot May Have Been Ground Zero

The 75-mile-wide crater could be something like a Chicxulub crater for the red planet.

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Nintendo's Q1 net profit drops 46% on forex losses

Japanese entertainment giant Nintendo said Tuesday its net profit in the first quarter dropped 46 percent due to exchange rate losses, but reported steady sales of its Switch gaming platform.

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Kæmpe brændstoflæk fra Norwegian-vikar kan have ødelagt landingsbane

En Airbus 340 dumpede store mængder jetfuel på en landingsbane i Florida ved en fejl. Jetfuel kan opløse asfaltens bindemiddel, forklarer dansk ekspert.

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Stamcelleforskning kaster nyt lys over huden

For første gang har forskere fra Københavns Universitet undersøgt og kortlagt talgkirtlers…

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Help with another? Not on PubPeer yet

This guest post by pseudonymous Cheshire, shows that everyone can become an image integrity sleuth. You don't need to be a scientist, just use common sense and some Twitter advice

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Siberia forest fires spark potential 'disaster' for Arctic

Gigantic forest fires have regularly raged through the vast expanses of Russia's Siberia, but the magnitude of this year's blazes has reached an exceptional level with fears of a long-term impact on the environment.

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Indonesia returns containers of waste to France, Hong Kong

Indonesia has returned seven shipping containers of illegally imported waste to France and Hong Kong, an official said Tuesday, marking the latest move by a Southeast Asian nation to send back rubbish to their wealthy places of origin.

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European price war squeezes Lufthansa hard in Q2

European airline giant Lufthansa on Tuesday reported tumbling net profits in the first quarter, saying higher operating costs and a European short-haul price war ate into the bottom line.

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Uber cuts marketing staff to reduce costs

Uber on Monday confirmed it is cutting 400 jobs from its marketing team of more than 1,200 workers to reduce costs and improve efficiency.

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A third of Guam reefs killed by rising ocean temperatures

Researchers have found that a third of Guam's coral reefs died due to rising ocean temperatures.

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Bayer says now targeted in 18,400 glyphosate cases in US

German pharmaceutical giant Bayer said Tuesday it is now targeted in some 18,400 US legal cases over glyphosate, a key herbicide ingredient that plaintiffs say caused grave illnesses like cancer.

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Bayer says now targeted in 18,400 glyphosate cases in US

German pharmaceutical giant Bayer said Tuesday it is now targeted in some 18,400 US legal cases over glyphosate, a key herbicide ingredient that plaintiffs say caused grave illnesses like cancer.

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Plastic junk spawns desert island disaster in Pacific

Floating plastic garbage has swamped a remote Pacific island once regarded as an environmental jewel and scientists say little can be done to save it while a throwaway culture persists.

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Capital One target of massive data breach

A hacker gained access to personal information from more than 100 million Capital One credit applications, the bank said Monday as federal authorities arrested a suspect in the case .

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Toby Walsh, A.I. Expert, Is Racing to Stop the Killer Robots

Autonomous weapons, capable of acting without human oversight, are closer than we think, Dr. Walsh believes, and must be banned.

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Would You Want a Computer to Judge Your Risk of H.I.V. Infection?

A new software algorithm decides which patients are most likely to become infected with the virus. Does the assessment stigmatize patients?

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California gas plant to be (mostly) re-powered with batteries + solar.

submitted by /u/toyota_tacoma_black [link] [comments]

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The Space Review: How space technology benefits the Earth

submitted by /u/Galileos_grandson [link] [comments]

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