Search Posts

nyheder2019maj07

Could Quantum Mechanics Explain the Existence of Spacetime?

Rod Serling knew all about dimensions. His Twilight Zone was a dimension of imagination, a dimension of sight and sound and mind, a dimension as vast as space and timeless as infinity. It was all very clear except for the space and time part, the dimensions of real life. Serling never explained them. Of course, ever since Einstein, scientists have also been scratching their heads about how to make

19h

“Magic: The Gathering” is officially the world’s most complex game

A new proof with important implications for game theory shows that no algorithm can possibly determine the winner.

9h

F-35 flyver alt for sjældent, fordi de mangler reservedele

60% af flyene skulle efter planen være kampklare på jorden. Men i virkelighed er kun 27% 'full mission capable.'

3h

Google Backs Plan to Use CRISPR to Cure Heart Disease

Big Money A new biotech startup has a bold plan to use CRISPR to end heart disease — and one of the world’s biggest tech companies is ready to help bring it to fruition. Verve Therapeutics came out of stealth mode on Tuesday with the announcement that it’d raised $58.5 million in financing, the majority of which came from GV (formerly Google Ventures), the venture capital arm of Google’s parent c

now

Seed abortion and the role of RNA Pol IV in seed development

ASPB is pleased to announce the publication in The Plant Cell of important research that explores the cause of seed abortion and the role of the enzyme RNA Pol IV to understand how seed development works.

now

Cruise's $1 Billion Infusion Shows the Stakes in Self-Driving Tech

Cruise, majority owned by GM, is at least the fourth company working on self-driving technology to raise $500 million or more in the past six months.

now

Google Pixel 3A, Pixel 3A XL Reviews: Best Deal in Android

For half the price of a high-end phone, you can get (almost) all the premium features. Read our full review.

now

Seed abortion and the role of RNA Pol IV in seed development

ASPB is pleased to announce the publication in The Plant Cell of important research that explores the cause of seed abortion and the role of the enzyme RNA Pol IV to understand how seed development works.

now

‘Scavengers’ attack muscles in newfound autoimmune disease

Researchers have identified a previously unknown autoimmune muscle disease involving sudden onset of debilitating muscle pain and weakness. Physicians could easily mistake the syndrome easily for other muscle diseases that require different treatment, so the researchers say they expect the findings to help treat patients appropriately. “We observed only four patients in more than 20 years, so it’

4min

Could this rare supernova resolve a longstanding origin debate?

Detection of a supernova with an unusual chemical signature by a team of astronomers led by Carnegie's Juna Kollmeier—and including Carnegie's Nidia Morrell, Anthony Piro, Mark Phillips, and Josh Simon—may hold the key to solving the longstanding mystery that is the source of these violent explosions. Observations taken by the Magellan telescopes at Carnegie's Las Campanas Observatory in Chile wer

7min

Huge Racial Disparities Found in Deaths Linked to Pregnancy

African-American, Native American and Alaska Native women are about three times more likely to die from causes related to pregnancy, compared to white women in the United States.

7min

Mystery eruption traced to dangerous Italian volcano

Mystery eruption traced to dangerous Italian volcano Mystery eruption traced to dangerous Italian volcano, Published online: 07 May 2019; doi:10.1038/d41586-019-01462-6 Some 29,000 years ago, the Campi Flegrei system near modern Naples buried an entire region in ash.

8min

The Air Force Just Tested a Laser Weapon for Fighter Jets

Successful Test A new laser weapon developed by the U.S. Air Force successfully shot down several missiles during a test run in late April. The Self-Protect High-Energy Laser Demonstrator, evocatively dubbed the “SHiELD,” is expected to someday be attached to fighter jets, providing them with the means to shoot down incoming air-launched missiles, according to Air Force Magazine , which would mak

8min

Daily Briefing: A crisis for life on Earth

Daily Briefing: A crisis for life on Earth Daily Briefing: A crisis for life on Earth, Published online: 07 May 2019; doi:10.1038/d41586-019-01474-2 Human activity is destroying the ecosystems that we depend on. Plus, Facebook is giving social scientists unprecedented access to its data and what medicine can teach academia about preventing burnout.

15min

Can a mobile phone-based behavioral intervention affect weight regain?

A scalable, mobile phone-based intervention designed to slow weight regain after an initial weight loss had no significant effect on participants' weight, according to a study published this week in PLOS Medicine by Falko Sniehotta from Newcastle University, UK and colleagues.

17min

Utilization and cancer yield of BI-RADS 3 lesions detected on high risk screening breast MRI

When appropriate, short-interval follow-up magnetic resonance imaging (MRI) can be used to identify early stage breast cancer and avoid unnecessary biopsies, according to a study to be presented at the ARRS 2019 Annual Meeting, set for May 5-10 in Honolulu, Hawaii.

17min

Rate of radiology resident recognition of non-accidental trauma

Radiology residency programs nationwide are not adequately teaching residents to accurately recognize and report child abuse, according to a study to be presented at the ARRS 2019 Annual Meeting, set for May 5-10 in Honolulu, Hawaii.

17min

Percutaneous ablation vs. surgery for hepatocellular carcinoma

Compared to surgery, percutaneous liver ablation interventions (IRs) in patients with hepatocellular carcinoma (HCC) are associated with lower inhospital mortality, length of hospital stay (LOS), and hospitalization costs, according to a study to be presented at the ARRS 2019 Annual Meeting, set for May 5-10 in Honolulu, Hawaii.

17min

Frequency and outcomes of new suspicious lesions on breast MRI in neoadjuvant therapy

During neoadjuvant chemotherapy, new suspicious findings detected on breast magnetic resonance imaging (MRI) during neoadjuvant therapy are most likely benign, according to a study to be presented at the ARRS 2019 Annual Meeting, set for May 5-10 in Honolulu, Hawaii.

17min

You don't have to say 'Hey, Google' to shut off your alarm anymore

Sometimes, the smallest changes are the most welcome ones. Google has removed the requirement to say "Hey, Google" before turning off an alarm, streamlining the Assistant …

21min

Can Language Shape the Way You Think About Gender?

submitted by /u/TheLavinGuy [link] [comments]

24min

Alzheimer's: How light therapy could protect the brain

A study uncovers the neuron and immune cell changes that explain why light therapy can reduce toxic brain proteins in mouse models of Alzheimer's disease.

29min

The search for new geologic sources of lithium could power a clean future

Futuristic clean-energy visions of electric vehicles are driving the hunt for lithium.

31min

Made in China: Fremtidens elbiler er fra Kina

Kinas elbilproduktion vokser eksplosivt – og det bekymrer USA, som forventes at indføre handels-barrierer.

33min

We've Made Astonishing Progress in Treating Stroke

During Stroke Awareness Month, it's important to note how far we've come, but also how much we still need to learn — Read more on ScientificAmerican.com

42min

We've Made Astonishing Progress in Treating Stroke

During Stroke Awareness Month, it's important to note how far we've come, but also how much we still need to learn — Read more on ScientificAmerican.com

43min

The World’s Strongest Laser is About to Simulate a Supernova

BFL The world’s most powerful laser is scheduled for a slate of experiments next year. The laser, in Romania, managed to fire at 10 petawatts — that’s one-tenth the power of all the sunlight that reaches Earth concentrated into a single laser beam — during a test run in March . Now, according to ExtremeTech , the scientists behind it intend to discover new high-energy cancer treatments and simula

43min

The Guardian view on extinction: time to rebel | Editorial

A million plant and animal species are under threat. Humans are largely to blame – but we will pay the cost too We humans pride ourselves on our ability to look beyond immediate concerns and think on a grander scale. While other creatures preen for mates, hunt prey or build homes, only humans ponder the nature of time, explore our place in the universe or are troubled by the question of what wiped

46min

Next-gen Google Assistant is crazy fast

It's been a year since Google first introduced Duplex, its automated reservation making feature for Assistant. The AI phone caller has rolled out to customers in 44 states, as …

49min

Microsoft Word’s New “AI Editor” Scolds You for Gendered Language

21st Century Clippy Microsoft has a plan to make sure your writing is inclusive — and it involves artificial intelligence. On Monday, the tech giant announced the upcoming integration of its AI-powered Ideas feature into Word Online, the cloud-based version of its popular word processor, Microsoft Word. According to a Microsoft blog post , in addition to helping writers improve the structure and

58min

A tiny mystery dinosaur from New Mexico is officially T. rex’s cousin

A newly identified dinosaur species called Suskityrannus hazelae fills a gap in tyrannosaur lineage.

1h

'Transformative Change' Needed: One Million Species Risk Extinction

One million species are threatened with extinction, more than ever before in human history, according to a landmark report released Monday from the United Nations. And humanity is responsible. "Ecosystems, species, wild populations, local varieties and breeds of domesticated plants and animals are shrinking, deteriorating or vanishing," said Josef Settele, an ecologist at the Helmholtz Center for

1h

1h

1h

1h

Amazon’s Newest Cashierless Store… Has a Cashier

Amazon Went Amazon just opened its latest Go store in New York City — the newest of its pioneering “cashierless” stores , in which customers can walk in, grab items leave, while being constantly monitored by a host of cameras and sensors that automatically charge them for the goods. But according to Business Insider , this store features an employee who can accept cash at a small, barely noticeab

1h

RNA editing implicated in chloroplast-to-nucleus communication [Commentaries]

Photosynthesis and respiration provide the chemical energy that sustains life on Earth. In eukaryotes, this essential metabolism is performed by chloroplasts and mitochondria. Although both of these organelles have small genomes that are remnants of their endosymbiotic origins, most of the proteins in these organelles are encoded by nuclear genes….

1h

Solar-powered synthesis of hydrocarbons from carbon dioxide and water [Commentaries]

The synthesis of hydrocarbons via electroreduction of CO2 is an attractive approach to store energy generated from intermittent renewable sources of electricity (e.g., solar) through formation of the high-energy C–C and C–H bonds of reduced carbon compounds (1, 2). Establishment of such processes also represents a critical step toward the…

1h

Peroxisomal {beta}-oxidation regulates histone acetylation and DNA methylation in Arabidopsis [Plant Biology]

Epigenetic markers, such as histone acetylation and DNA methylation, determine chromatin organization. In eukaryotic cells, metabolites from organelles or the cytosol affect epigenetic modifications. However, the relationships between metabolites and epigenetic modifications are not well understood in plants. We found that peroxisomal acyl-CoA oxidase 4 (ACX4), an enzyme in the…

1h

Defect engineering of metal-oxide interface for proximity of photooxidation and photoreduction [Applied Physical Sciences]

Close proximity between different catalytic sites is crucial for accelerating or even enabling many important catalytic reactions. Photooxidation and photoreduction in photocatalysis are generally separated from each other, which arises from the hole–electron separation on photocatalyst surface. Here, we show with widely studied photocatalyst Pt/TiO2 as a model, that concentrating…

1h

Second-order induction in prediction problems [Economic Sciences]

Agents make predictions based on similar past cases, while also learning the relative importance of various attributes in judging similarity. We ask whether the resulting “empirically optimal similarity function” (EOSF) is unique and how easy it is to find it. We show that with many observations and few relevant variables,…

1h

Heterogeneity in refractory acute myeloid leukemia [Medical Sciences]

Successful clinical remission to therapy for acute myeloid leukemia (AML) is required for long-term survival to be achieved. Despite trends in improved survival due to better supportive care, up to 40% of patients will have refractory disease, which has a poorly understood biology and carries a dismal prognosis. The development…

1h

A randomized control trial evaluating the effects of police body-worn cameras [Social Sciences]

Police body-worn cameras (BWCs) have been widely promoted as a technological mechanism to improve policing and the perceived legitimacy of police and legal institutions, yet evidence of their effectiveness is limited. To estimate the effects of BWCs, we conducted a randomized controlled trial involving 2,224 Metropolitan Police Department officers in…

1h

Cis- and trans-acting variants contribute to survivorship in a naive Drosophila melanogaster population exposed to ryanoid insecticides [Evolution]

Insecticide resistance is a paradigm of microevolution, and insecticides are responsible for the strongest cases of recent selection in the genome of Drosophila melanogaster. Here we use a naïve population and a novel insecticide class to examine the ab initio genetic architecture of a potential selective response. Genome-wide association studies…

1h

Remodeling of ER-plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis [Cell Biology]

Store-operated Ca2+ entry (SOCE), mediated by the endoplasmic reticulum (ER) Ca2+ sensor stromal interaction molecule 1 (STIM1) and the plasma membrane (PM) channel Orai1, is inhibited during mitosis. STIM1 phosphorylation has been suggested to mediate this inhibition, but it is unclear whether additional pathways are involved. Here, we demonstrate using…

1h

Extrinsic conditions influence the self-association and structure of IF1, the regulatory protein of mitochondrial ATP synthase [Biochemistry]

The endogenous inhibitor of ATP synthase in mitochondria, called IF1, conserves cellular energy when the proton-motive force collapses by inhibiting ATP hydrolysis. Around neutrality, the 84-amino-acid bovine IF1 is thought to self-assemble into active dimers and, under alkaline conditions, into inactive tetramers and higher oligomers. Dimerization is mediated by formation…

1h

Conching chocolate is a prototypical transition from frictionally jammed solid to flowable suspension with maximal solid content [Physics]

The mixing of a powder of 10- to 50-μm primary particles into a liquid to form a dispersion with the highest possible solid content is a common industrial operation. Building on recent advances in the rheology of such “granular dispersions,” we study a paradigmatic example of such powder incorporation: the…

1h

Heat stress directly impairs gut integrity and recruits distinct immune cell populations into the bovine intestine [Agricultural Sciences]

High ambient temperature has multiple potential effects on the organism such as hyperthermia, endotoxemia, and/or systemic inflammation. However, it is often difficult to discriminate between cause and consequence of phenotypic effects, such as the indirect influence of heat stress via reduced food intake. Lactating dairy cows are a particularly sensitive…

1h

New Laplace and Helmholtz solvers [Applied Mathematics]

Numerical algorithms based on rational functions are introduced that solve the Laplace and Helmholtz equations on 2D domains with corners quickly and accurately, despite the corner singularities.

1h

Reactive oxygen species as the long arm of bactericidal antibiotics [Commentaries]

Stress tolerance in bacterial populations is the ability to restore homeostasis after protracted exposure to lethal agents. The longer a bacterial population can withstand a lethal agent, the more tolerant it is considered to be. In the last two decades, antibiotic tolerance was given special attention because of a possible…

1h

Genomic correlates of clinical outcome in advanced prostate cancer [Medical Sciences]

Heterogeneity in the genomic landscape of metastatic prostate cancer has become apparent through several comprehensive profiling efforts, but little is known about the impact of this heterogeneity on clinical outcome. Here, we report comprehensive genomic and transcriptomic analysis of 429 patients with metastatic castration-resistant prostate cancer (mCRPC) linked with longitudinal…

1h

Rivers across the Siberian Arctic unearth the patterns of carbon release from thawing permafrost [Environmental Sciences]

Climate warming is expected to mobilize northern permafrost and peat organic carbon (PP-C), yet magnitudes and system specifics of even current releases are poorly constrained. While part of the PP-C will degrade at point of thaw to CO2 and CH4 to directly amplify global warming, another part will enter the…

1h

FAM64A positively regulates STAT3 activity to promote Th17 differentiation and colitis-associated carcinogenesis [Immunology and Inflammation]

STAT3 is a transcription factor that plays central roles in various physiological processes, including differentiation of Th cells. Its deregulation results in serious diseases, including inflammatory diseases and cancer. The mechanisms related to how STAT3 activity is regulated remain enigmatic. Here we show that overexpression of FAM64A potentiates IL-6–induced activation…

1h

Structure-guided function discovery of an NRPS-like glycine betaine reductase for choline biosynthesis in fungi [Chemistry]

Nonribosomal peptide synthetases (NRPSs) and NRPS-like enzymes have diverse functions in primary and secondary metabolisms. By using a structure-guided approach, we uncovered the function of a NRPS-like enzyme with unusual domain architecture, catalyzing two sequential two-electron reductions of glycine betaine to choline. Structural analysis based on the homology model suggests…

1h

Fundamental bounds on learning performance in neural circuits [Neuroscience]

How does the size of a neural circuit influence its learning performance? Larger brains tend to be found in species with higher cognitive function and learning ability. Intuitively, we expect the learning capacity of a neural circuit to grow with the number of neurons and synapses. We show how adding…

1h

Wnt canonical pathway activates macropinocytosis and lysosomal degradation of extracellular proteins [Cell Biology]

Canonical Wnt signaling is emerging as a major regulator of endocytosis. Wnt treatment markedly increased the endocytosis and degradation in lysosomes of BSA. In this study, we report that in addition to receptor-mediated endocytosis, Wnt also triggers the intake of large amounts of extracellular fluid by macropinocytosis, a nonreceptor-mediated actin-driven…

1h

Unraveling ancestry, kinship, and violence in a Late Neolithic mass grave [Genetics]

The third millennium BCE was a period of major cultural and demographic changes in Europe that signaled the beginning of the Bronze Age. People from the Pontic steppe expanded westward, leading to the formation of the Corded Ware complex and transforming the genetic landscape of Europe. At the time, the…

1h

Considering adaptive genetic variation in climate change vulnerability assessment reduces species range loss projections [Evolution]

Local adaptations can determine the potential of populations to respond to environmental changes, yet adaptive genetic variation is commonly ignored in models forecasting species vulnerability and biogeographical shifts under future climate change. Here we integrate genomic and ecological modeling approaches to identify genetic adaptations associated with climate in two cryptic…

1h

Profile of Aravinda Chakravarti [Profiles]

Many of the genetic variations uncovered by genome-wide dragnets are bycatch, not primary disease culprits. Separating causality from coincidence in this sea of data is challenging, especially when many of the candidates do not reside in the coding portion of the genome. Aravinda Chakravarti, director of New York University’s Center…

1h

Chemical evidence for the use of multiple psychotropic plants in a 1,000-year-old ritual bundle from South America [Anthropology]

Over several millennia, various native plant species in South America have been used for their healing and psychoactive properties. Chemical analysis of archaeological artifacts provides an opportunity to study the use of psychoactive plants in the past and to better understand ancient botanical knowledge systems. Liquid chromatography tandem mass spectrometry…

1h

Brain ventricular volume changes induced by long-duration spaceflight [Neuroscience]

Long-duration spaceflight induces detrimental changes in human physiology. Its residual effects and mechanisms remain unclear. We prospectively investigated the changes in cerebrospinal fluid (CSF) volume of the brain ventricular regions in space crew by means of a region of interest analysis on structural brain scans. Cosmonaut MRI data were investigated…

1h

Endothelial NMDA receptors mediate activity-dependent brain hemodynamic responses in mice [Neuroscience]

Dynamic coupling of blood supply with energy demand is a natural brain property that requires signaling between synapses and endothelial cells. Our previous work showed that cortical arteriole lumen diameter is regulated by N-methyl-d-aspartate receptors (NMDARs) expressed by brain endothelial cells. The purpose of this study was to determine whether…

1h

Dynamic microscale flow patterning using electrical modulation of zeta potential [Engineering]

The ability to move fluids at the microscale is at the core of many scientific and technological advancements. Despite its importance, microscale flow control remains highly limited by the use of discrete channels and mechanical valves, and relies on fixed geometries. Here we present an alternative mechanism that leverages localized…

1h

Social media’s enduring effect on adolescent life satisfaction [Psychological and Cognitive Sciences]

In this study, we used large-scale representative panel data to disentangle the between-person and within-person relations linking adolescent social media use and well-being. We found that social media use is not, in and of itself, a strong predictor of life satisfaction across the adolescent population. Instead, social media effects are…

1h

Dated language phylogenies shed light on the ancestry of Sino-Tibetan [Anthropology]

The Sino-Tibetan language family is one of the world’s largest and most prominent families, spoken by nearly 1.4 billion people. Despite the importance of the Sino-Tibetan languages, their prehistory remains controversial, with ongoing debate about when and where they originated. To shed light on this debate we develop a database…

1h

Correction for Helbert et al., Discovery of novel carbohydrate-active enzymes through the rational exploration of the protein sequences space [Corrections]

BIOCHEMISTRY Correction for “Discovery of novel carbohydrate-active enzymes through the rational exploration of the protein sequences space,” by William Helbert, Laurent Poulet, Sophie Drouillard, Sophie Mathieu, Mélanie Loiodice, Marie Couturier, Vincent Lombard, Nicolas Terrapon, Jeremy Turchetto, Renaud Vincentelli, and Bernard Henrissat, which was first published March 8, 2019; 10.1073/pnas.18

1h

QnAs with Alexander Levitzki [QnAs]

Alexander Levitzki has made significant contributions to the fields of enzymology, signal transduction, and cancer research. Early in his career, Levitzki studied allosteric enzymes, followed by key discoveries about the signal transduction of G protein-coupled receptors, particularly the coupling of beta-adrenergic receptors with G proteins, which are central to cellular…

1h

Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis [Microbiology]

Mycobacterium tuberculosis (Mtb) killed more people in 2017 than any other single infectious agent. This dangerous pathogen is able to withstand stresses imposed by the immune system and tolerate exposure to antibiotics, resulting in persistent infection. The global tuberculosis (TB) epidemic has been exacerbated by the emergence of mutant strains…

1h

Nahua mushroom gatherers use area-restricted search strategies that conform to marginal value theorem predictions [Anthropology]

We develop a method of analysis for testing the marginal value theorem (MVT) in natural settings that does not require an independent definition or mapping of patches. We draw on recent theoretical work on area-restricted search (ARS) that links turning-angle and step-size changes to geographically localized encounter-rates. These models allow…

1h

Using naturally occurring climate resilient corals to construct bleaching-resistant nurseries [Sustainability Science]

Ecological restoration of forests, meadows, reefs, or other foundational ecosystems during climate change depends on the discovery and use of individuals able to withstand future conditions. For coral reefs, climate-tolerant corals might not remain tolerant in different environments because of widespread environmental adjustment of coral physiology and symbionts. Here, we…

1h

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs [Neuroscience]

There is a growing body of evidence linking maternal overnutrition to obesity and psychopathology that can be conserved across multiple generations. Recently, we demonstrated in a maternal high-fat diet (HFD; MHFD) mouse model that MHFD induced enhanced hedonic behaviors and obesogenic phenotypes that were conserved across three generations via the…

1h

In This Issue [This Week in PNAS]

Kin relationships in megalithic burial sites The Ansarve dolmen, Island of Gotland, Sweden. Megalithic tombs emerged in France around 4500 BCE and spread throughout Europe. However, the cultural origin of such structures and their role in Neolithic societies has been debated. Federico Sánchez-Quinto, Helena Malmström, Magdalena Fraser, et al. (pp….

1h

Endometrial carcinoma may favor partial, but not complete, loss of the TGF-{beta} signaling pathway [Biological Sciences]

The TGF-β signaling pathway is involved in the development of many types of cancer. In two recent PNAS papers, Montsivais et al. (1) and Kriseman et al. (2) of the Matzuk laboratory investigate the role of the TGF-β signaling pathway in endometrial carcinoma by using gene knockout mouse models. They…

1h

Reply to Liu et al.: ALK5-mediated tumor suppressor signaling through SMAD2 and SMAD3 in the uterus [Biological Sciences]

Our recent publications in PNAS (1, 2) describe the phenotypic effects of loss of activin-like kinase 5; transforming growth factor β receptor 1 (ALK5;TGFBR1) or Smad2 and Smad3 in the mouse uterus and are accompanied by a commentary by Li (3). Our conclusions are that this pathway acts as a…

1h

QnAs with Stephen R. Forrest [QnAs]

The smartphone revolution capitalized on generations of advancements in inorganic semiconductor design. Engineers and materials scientists shrank electronic components, primarily manufactured from silicon, germanium, and gallium arsenide, and combined them with light-emitting diodes (LEDs) that could be assembled into pocket-sized computers. Progress in optoelectronic technologies, which combine o

1h

Several glasses of water but one dense liquid [Applied Physical Sciences]

Depending on the external temperature and pressure, pure substances can assume different phases, two of them (gas and liquid) lacking long-range order. The crystal phase, especially in molecular systems, can assume a multiplicity of distinct ordered structures, differing in the relative position and orientation of the molecules. In the case…

1h

Inequality brokered [Social Sciences]

Factors that increase or decrease social inequalities rarely occur in isolation. Unless checked, these factors mutually reinforce each other across human life spans, sustain unjust hierarchies across historical time, and spill over from their intended targets to those around them. For example, sexual orientation structures privilege and exclusion in myriad…

1h

Hydrogen bonding steers the product selectivity of electrocatalytic CO reduction [Chemistry]

The product selectivity of many heterogeneous electrocatalytic processes is profoundly affected by the liquid side of the electrocatalytic interface. The electrocatalytic reduction of CO to hydrocarbons on Cu electrodes is a prototypical example of such a process. However, probing the interactions of surface-bound intermediates with their liquid reaction environment poses…

1h

Expeditious, scalable solution growth of metal oxide films by combustion blade coating for flexible electronics [Chemistry]

Metal oxide (MO) semiconductor thin films prepared from solution typically require multiple hours of thermal annealing to achieve optimal lattice densification, efficient charge transport, and stable device operation, presenting a major barrier to roll-to-roll manufacturing. Here, we report a highly efficient, cofuel-assisted scalable combustion blade-coating (CBC) process for MO film…

1h

Signatures of slip in dewetting polymer films [Physics]

Thin polymer films on hydrophobic substrates are susceptible to rupture and hole formation. This, in turn, initiates a complex dewetting process, which ultimately leads to characteristic droplet patterns. Experimental and theoretical studies suggest that the type of droplet pattern depends on the specific interfacial condition between the polymer and the…

1h

Toward personalized cognitive diagnostics of at-genetic-risk Alzheimer’s disease [Psychological and Cognitive Sciences]

Spatial navigation is emerging as a critical factor in identifying preclinical Alzheimer’s disease (AD). However, the impact of interindividual navigation ability and demographic risk factors (e.g., APOE, age, and sex) on spatial navigation make it difficult to identify persons “at high risk” of AD in the preclinical stages. In the…

1h

Lending practices to same-sex borrowers [Social Sciences]

Using massive US mortgage lending data, we propose a method to infer a borrower’s sexual orientation indirectly without a self-identification requirement and demonstrate the method’s potential to approximately measure the sexual orientation of the US population at the local level annually over decades. We continue to examine the lending practices…

1h

Systematic assessment of the sex ratio at birth for all countries and estimation of national imbalances and regional reference levels [Social Sciences]

The sex ratio at birth (SRB; ratio of male to female live births) imbalance in parts of the world over the past few decades is a direct consequence of sex-selective abortion, driven by the coexistence of son preference, readily available technology of prenatal sex determination, and fertility decline. Estimation of…

1h

RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in Saccharomyces cerevisiae [Applied Biological Sciences]

The cellular machinery that supports protein synthesis and secretion lies at the foundation of cell factory-centered protein production. Due to the complexity of such cellular machinery, the challenge in generating a superior cell factory is to fully exploit the production potential by finding beneficial targets for optimized strains, which ideally…

1h

The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity [Biochemistry]

Deoxynucleotide triphosphohydrolases (dNTPases) play a critical role in cellular survival and DNA replication through the proper maintenance of cellular dNTP pools. While the vast majority of these enzymes display broad activity toward canonical dNTPs, such as the dNTPase SAMHD1 that blocks reverse transcription of retroviruses in macrophages by maintaining dNTP…

1h

Component of splicing factor SF3b plays a key role in translational control of polyribosomes on the endoplasmic reticulum [Biochemistry]

One of the morphological hallmarks of terminally differentiated secretory cells is highly proliferated membrane of the rough endoplasmic reticulum (ER), but the molecular basis for the high rate of protein biosynthesis in these cells remains poorly documented. An important aspect of ER translational control is the molecular mechanism that supports…

1h

Telomere DNA G-quadruplex folding within actively extending human telomerase [Biochemistry]

Telomerase reverse transcribes short guanine (G)-rich DNA repeat sequences from its internal RNA template to maintain telomere length. G-rich telomere DNA repeats readily fold into G-quadruplex (GQ) structures in vitro, and the presence of GQ-prone sequences throughout the genome introduces challenges to replication in vivo. Using a combination of ensemble…

1h

Topological descriptions of protein folding [Biophysics and Computational Biology]

How knotted proteins fold has remained controversial since the identification of deeply knotted proteins nearly two decades ago. Both computational and experimental approaches have been used to investigate protein knot formation. Motivated by the computer simulations of Bölinger et al. [Bölinger D, et al. (2010) PLoS Comput Biol 6:e1000731] for…

1h

Three-dimensional architecture of epithelial primary cilia [Biophysics and Computational Biology]

We report a complete 3D structural model of typical epithelial primary cilia based on structural maps of full-length primary cilia obtained by serial section electron tomography. Our data demonstrate the architecture of primary cilia differs extensively from the commonly acknowledged 9+0 paradigm. The axoneme structure is relatively stable but gradually…

1h

Unifying photocycle model for light adaptation and temporal evolution of cation conductance in channelrhodopsin-2 [Biophysics and Computational Biology]

Although channelrhodopsin (ChR) is a widely applied light-activated ion channel, important properties such as light adaptation, photocurrent inactivation, and alteration of the ion selectivity during continuous illumination are not well understood from a molecular perspective. Herein, we address these open questions using single-turnover electrophysiology, time-resolved step-scan FTIR, and Raman s

1h

Structural mechanism for Bruton’s tyrosine kinase activation at the cell membrane [Biophysics and Computational Biology]

Bruton’s tyrosine kinase (Btk) is critical for B cell proliferation and activation, and the development of Btk inhibitors is a vigorously pursued strategy for the treatment of various B cell malignancies. A detailed mechanistic understanding of Btk activation has, however, been lacking. Here, inspired by a previous suggestion that Btk…

1h

Forging tools for refining predicted protein structures [Biophysics and Computational Biology]

Refining predicted protein structures with all-atom molecular dynamics simulations is one route to producing, entirely by computational means, structural models of proteins that rival in quality those that are determined by X-ray diffraction experiments. Slow rearrangements within the compact folded state, however, make routine refinement of predicted structures by unrestrained…

1h

Human mutations highlight an intersubunit cation-{pi} bond that stabilizes the closed but not open or inactivated states of TRPV channels [Biophysics and Computational Biology]

An adequate response of a living cell to the ever-changing environment requires integration of numerous sensory inputs. In many cases, it can be achieved even at the level of a single receptor molecule. Polymodal transient receptor potential (TRP) channels have been shown to integrate mechanical, chemical, electric, and thermal stimuli….

1h

Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1 [Cell Biology]

The Hippo-YAP/TAZ signaling pathway plays a pivotal role in growth control during development and regeneration and its dysregulation is widely implicated in various cancers. To further understand the cellular and molecular mechanisms underlying Hippo signaling regulation, we have found that activities of core Hippo signaling components, large tumor suppressor (LATS)…

1h

Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance [Cell Biology]

The RAS family of proto-oncogenes are among the most commonly mutated genes in human cancers and predict poor clinical outcome. Several mechanisms underlying oncogenic RAS transformation are well documented, including constitutive signaling through the RAF-MEK-ERK proproliferative pathway as well as the PI3K-AKT prosurvival pathway. Notably, control of redox balance has…

1h

Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration [Cell Biology]

An increasing number of studies reveal the importance of long noncoding RNAs (lncRNAs) in gene expression control underlying many physiological and pathological processes. However, their role in skin wound healing remains poorly understood. Our study focused on a skin-specific lncRNA, LOC105372576, whose expression was increased during physiological wound healing. In…

1h

Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers [Cell Biology]

Using an inducible, inflammatory model of breast cellular transformation, we describe the transcriptional regulatory network mediated by STAT3, NF-κB, and AP-1 factors on a genomic scale. These proinflammatory regulators form transcriptional complexes that directly regulate the expression of hundreds of genes in oncogenic pathways via a positive feedback loop. This…

1h

Frequency of DNA end joining in trans is not determined by the predamage spatial proximity of double-strand breaks in yeast [Genetics]

DNA double-strand breaks (DSBs) are serious genomic insults that can lead to chromosomal rearrangements if repaired incorrectly. To gain insight into the nuclear mechanisms contributing to these rearrangements, we developed an assay in yeast to measure cis (same site) vs. trans (different site) repair for the majority process of precise…

1h

Overlooked roles of DNA damage and maternal age in generating human germline mutations [Genetics]

The textbook view that most germline mutations in mammals arise from replication errors is indirectly supported by the fact that there are both more mutations and more cell divisions in the male than in the female germline. When analyzing large de novo mutation datasets in humans, we find multiple lines…

1h

In silico learning of tumor evolution through mutational time series [Genetics]

Cancer arises through the accumulation of somatic mutations over time. Understanding the sequence of mutation occurrence during cancer progression can assist early and accurate diagnosis and improve clinical decision-making. Here we employ long short-term memory (LSTM) networks, a class of recurrent neural network, to learn the evolution of a tumor…

1h

Transcription factors IRF8 and PU.1 are required for follicular B cell development and BCL6-driven germinal center responses [Immunology and Inflammation]

The IRF and Ets families of transcription factors regulate the expression of a range of genes involved in immune cell development and function. However, the understanding of the molecular mechanisms of each family member has been limited due to their redundancy and broad effects on multiple lineages of cells. Here,…

1h

Cystine-glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity [Medical Sciences]

T cell-invigorating cancer immunotherapies have near-curative potential. However, their clinical benefit is currently limited, as only a fraction of patients respond, suggesting that these regimens may benefit from combination with tumor-targeting treatments. As oncogenic progression is accompanied by alterations in metabolic pathways, tumors often become heavily reliant on antioxidant machinery..

1h

Exploratory trial of a biepitopic CAR T-targeting B cell maturation antigen in relapsed/refractory multiple myeloma [Medical Sciences]

Relapsed and refractory (R/R) multiple myeloma (MM) patients have very poor prognosis. Chimeric antigen receptor modified T (CAR T) cells is an emerging approach in treating hematopoietic malignancies. Here we conducted the clinical trial of a biepitope-targeting CAR T against B cell maturation antigen (BCMA) (LCAR-B38M) in 17 R/R MM…

1h

Structural insights into RNA recognition by the Chikungunya virus nsP2 helicase [Microbiology]

Chikungunya virus (CHIKV) is transmitted to humans through mosquitoes and causes Chikungunya fever. Nonstructural protein 2 (nsP2) exhibits the protease and RNA helicase activities that are required for viral RNA replication and transcription. Unlike for the C-terminal protease, the structure of the N-terminal RNA helicase (nsP2h) has not been determined….

1h

HIV-1 Vpr counteracts HLTF-mediated restriction of HIV-1 infection in T cells [Microbiology]

Lentiviruses, including HIV-1, possess the ability to enter the nucleus through nuclear pore complexes and can infect interphase cells, including those actively replicating chromosomal DNA. Viral accessory proteins hijack host cell E3 enzymes to antagonize intrinsic defenses, and thereby provide a more permissive environment for virus replication. The HIV-1 Vpr…

1h

Alarmone Ap4A is elevated by aminoglycoside antibiotics and enhances their bactericidal activity [Microbiology]

Second messenger molecules play important roles in the responses to various stimuli that can determine a cell's fate under stress conditions. Here, we report that lethal concentrations of aminoglycoside antibiotics result in the production of a dinucleotide alarmone metabolite–diadenosine tetraphosphate (Ap4A), which promotes bacterial cell killing by this class of…

1h

A neural signature of pattern separation in the monkey hippocampus [Neuroscience]

The CA3 and dentate gyrus (DG) regions of the hippocampus are considered key for disambiguating sensory inputs from similar experiences in memory, a process termed pattern separation. The neural mechanisms underlying pattern separation, however, have been difficult to compare across species: rodents offer robust recording methods with less human-centric tasks,…

1h

Preventing adolescent stress-induced cognitive and microbiome changes by diet [Neuroscience]

Psychological stress during adolescence may cause enduring cognitive deficits and anxiety in both humans and animals, accompanied by rearrangement of numerous brain structures and functions. A healthy diet is essential for proper brain development and maintenance of optimal cognitive functions during adulthood. Furthermore, nutritional components profoundly affect the intestinal community…

1h

Data gaps and opportunities for comparative and conservation biology [Population Biology]

Biodiversity loss is a major challenge. Over the past century, the average rate of vertebrate extinction has been about 100-fold higher than the estimated background rate and population declines continue to increase globally. Birth and death rates determine the pace of population increase or decline, thus driving the expansion or…

1h

Living with plague: Lessons from the Soviet Union’s antiplague system [Applied Biological Sciences]

Zoonoses, such as plague, are primarily animal diseases that spill over into human populations. While the goal of eradicating such diseases is enticing, historical experience validates abandoning eradication in favor of ecologically based control strategies (which reduce morbidity and mortality to a locally accepted risk level). During the 20th century,…

1h

Megalithic tombs in western and northern Neolithic Europe were linked to a kindred society [Anthropology]

Paleogenomic and archaeological studies show that Neolithic lifeways spread from the Fertile Crescent into Europe around 9000 BCE, reaching northwestern Europe by 4000 BCE. Starting around 4500 BCE, a new phenomenon of constructing megalithic monuments, particularly for funerary practices, emerged along the Atlantic façade. While it has been suggested that…

1h

Comparing signals of natural selection between three Indigenous North American populations [Anthropology]

While many studies have highlighted human adaptations to diverse environments worldwide, genomic studies of natural selection in Indigenous populations in the Americas have been absent from this literature until very recently. Since humans first entered the Americas some 20,000 years ago, they have settled in many new environments across the…

1h

A pair of native fungal pathogens drives decline of a new invasive herbivore [Applied Biological Sciences]

Two North American fungal pathogens caused a coepizootic leading to localized collapse of an outbreak population of the newly invasive planthopper pest, the spotted lanternfly (Lycorma delicatula), in the eastern United States. The pathogens partitioned the habitat, with the majority of L. delicatula on tree trunks killed by Batkoa major,…

1h

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition [Applied Biological Sciences]

Visceral leishmaniasis (VL), caused by the protozoan parasites Leishmania donovani and Leishmania infantum, is one of the major parasitic diseases worldwide. There is an urgent need for new drugs to treat VL, because current therapies are unfit for purpose in a resource-poor setting. Here, we describe the development of a…

1h

Radio frequency transmitter based on a laser frequency comb [Applied Physical Sciences]

Since the days of Hertz, radio transmitters have evolved from rudimentary circuits emitting around 50 MHz to modern ubiquitous Wi-Fi devices operating at gigahertz radio bands. As wireless data traffic continues to increase, there is a need for new communication technologies capable of high-frequency operation for high-speed data transfer. Here,…

1h

Large bandgap of pressurized trilayer graphene [Applied Physical Sciences]

Graphene-based nanodevices have been developed rapidly and are now considered a strong contender for postsilicon electronics. However, one challenge facing graphene-based transistors is opening a sizable bandgap in graphene. The largest bandgap achieved so far is several hundred meV in bilayer graphene, but this value is still far below the…

1h

Evidence for high-density liquid water between 0.1 and 0.3 GPa near 150 K [Applied Physical Sciences]

Thermal stability against crystallization upon isobaric heating at pressure 0.1 ≤ P ≤ 1.9 GPa is compared for five variants of high- (HDA) and very high-density amorphous ice (VHDA) with different preparation history. At 0.1–0.3 GPa expanded HDA (eHDA) and VHDA reach the same state before crystallization, which we infer…

1h

Emergence of topological electronic phases in elemental lithium under pressure [Applied Physical Sciences]

Lithium, a prototypical simple metal under ambient conditions, has a surprisingly rich phase diagram under pressure, taking up several structures with reduced symmetry, low coordination numbers, and even semiconducting character with increasing density. Using first-principles calculations, we demonstrate that some predicted high-pressure phases of elemental Li also host topological electronic…

1h

Foam as a self-assembling amorphous photonic band gap material [Applied Physical Sciences]

We show that slightly polydisperse disordered 2D foams can be used as a self-assembled template for isotropic photonic band gap (PBG) materials for transverse electric (TE) polarization. Calculations based on in-house experimental and simulated foam structures demonstrate that, at sufficient refractive index contrast, a dry foam organization with threefold nodes…

1h

Dynamic super-resolution structured illumination imaging in the living brain [Applied Physical Sciences]

Cells in the brain act as components of extended networks. Therefore, to understand neurobiological processes in a physiological context, it is essential to study them in vivo. Super-resolution microscopy has spatial resolution beyond the diffraction limit, thus promising to provide structural and functional insights that are not accessible with conventional…

1h

Helical nanofiber yarn enabling highly stretchable engineered microtissue [Biophysics and Computational Biology]

Development of microtissues that possess mechanical properties mimicking those of native stretchable tissues, such as muscle and tendon, is in high demand for tissue engineering and regenerative medicine. However, regardless of the significant advances in synthetic biomaterials, it remains challenging to fabricate living microtissue with high stretchability because application of…

1h

Electrically induced bacterial membrane-potential dynamics correspond to cellular proliferation capacity [Biophysics and Computational Biology]

Membrane-potential dynamics mediate bacterial electrical signaling at both intra- and intercellular levels. Membrane potential is also central to cellular proliferation. It is unclear whether the cellular response to external electrical stimuli is influenced by the cellular proliferative capacity. A new strategy enabling electrical stimulation of bacteria with simultaneous monitoring of…

1h

Variation in sequence dynamics improves maintenance of stereotyped behavior in an example from bird song [Biophysics and Computational Biology]

Performing a stereotyped behavior successfully over time requires both maintaining performance quality and adapting efficiently to environmental or physical changes affecting performance. The bird song system is a paradigmatic example of learning a stereotyped behavior and therefore is a good place to study the interaction of these two goals. Through…

1h

Shugoshin protects centromere pairing and promotes segregation of nonexchange partner chromosomes in meiosis [Cell Biology]

Faithful chromosome segregation during meiosis I depends upon the formation of connections between homologous chromosomes. Crossovers between homologs connect the partners, allowing them to attach to the meiotic spindle as a unit, such that they migrate away from one another at anaphase I. Homologous partners also become connected by pairing…

1h

Formation and surface-stabilizing contributions to bare nanoemulsions created with negligible surface charge [Chemistry]

The stabilization of nanoemulsions, nanosized oil droplets dispersed in water, is commonly achieved through the addition of surfactants and polymers. However, nanoemulsions in the absence of emulsifiers have been observed to acquire a significant negative charge at their surface, which ultimately contributes to their stability. While the source of this…

1h

Forty-six years of Greenland Ice Sheet mass balance from 1972 to 2018 [Earth, Atmospheric, and Planetary Sciences]

We reconstruct the mass balance of the Greenland Ice Sheet using a comprehensive survey of thickness, surface elevation, velocity, and surface mass balance (SMB) of 260 glaciers from 1972 to 2018. We calculate mass discharge, D, into the ocean directly for 107 glaciers (85% of D) and indirectly for 110…

1h

Opinion: To create sustainable seafood industries, the United States needs a better accounting of imports and exports [Economic Sciences]

Global seafood trade nearly doubled in recent decades, fueled by decreasing transportation costs, advances in preservation and processing technologies, and open trade policies and is now among the most highly traded commodities (1). The United States is currently the world’s top seafood importer and among the top five exporters (2)….

1h

Sideways and stable crack propagation in a silicone elastomer [Engineering]

We have discovered a peculiar form of fracture that occurs in a highly stretchable silicone elastomer (Smooth-On Ecoflex 00–30). Under certain conditions, cracks propagate in a direction perpendicular to the initial precut and in the direction of the applied load. In other words, the crack deviates from the standard trajectory…

1h

Collaboration and competition between active sheets for self-propelled particles [Engineering]

Biological species routinely collaborate for their mutual benefit or compete for available resources, thereby displaying dynamic behavior that is challenging to replicate in synthetic systems. Here we use computational modeling to design microscopic, chemically active sheets and self-propelled particles encompassing the appropriate synergistic interactions to exhibit bioinspired feeding, fleeing,

1h

Family quarrels in seeds and rapid adaptive evolution in Arabidopsis [Evolution]

Evolutionary conflict can drive rapid adaptive evolution, sometimes called an arms race, because each party needs to respond continually to the adaptations of the other. Evidence for such arms races can sometimes be seen in morphology, in behavior, or in the genes underlying sexual interactions of host−pathogen interactions, but is…

1h

Genetic variation across the human olfactory receptor repertoire alters odor perception [Genetics]

Humans use a family of more than 400 olfactory receptors (ORs) to detect odors, but there is currently no model that can predict olfactory perception from receptor activity patterns. Genetic variation in human ORs is abundant and alters receptor function, allowing us to examine the relationship between receptor function and…

1h

Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis, potentially impacting cognitive functions [Medical Sciences]

Sepsis induces heparanase-mediated degradation of the endothelial glycocalyx, a heparan sulfate-enriched endovascular layer critical to vascular homeostasis, releasing highly sulfated domains of heparan sulfate into the circulation. These domains are oligosaccharides rich in heparin-like trisulfated disaccharide repeating units. Using a chemoenzymatic approach, an undecasaccharide containing a uni

1h

Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis [Medical Sciences]

Fatty liver disease (FLD) is a disorder in which accumulation of triglycerides (TGs) in the liver can lead to inflammation, fibrosis, and cirrhosis. Previously, we identified a variant (I148M) in patatin-like phospholipase domain-containing protein 3 (PNPLA3) that is strongly associated with FLD, but the mechanistic basis for the association remains…

1h

Genome-wide CRISPR screen for Zika virus resistance in human neural cells [Medical Sciences]

Zika virus (ZIKV) is a neurotropic and neurovirulent arbovirus that has severe detrimental impact on the developing human fetal brain. To date, little is known about the factors required for ZIKV infection of human neural cells. We identified ZIKV host genes in human pluripotent stem cell (hPSC)-derived neural progenitors (NPs)…

1h

Tiling and somatotopic alignment of mammalian low-threshold mechanoreceptors [Neuroscience]

Innocuous mechanical stimuli acting on the skin are detected by sensory neurons, known as low-threshold mechanoreceptors (LTMRs). LTMRs are classified based on their response properties, action potential conduction velocity, rate of adaptation to static indentation of the skin, and terminal anatomy. Here, we report organizational properties of the cutaneous and…

1h

Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia-related genes [Neuroscience]

Schizophrenia has been conceived as a disorder of brain connectivity, but it is unclear how this network phenotype is related to the underlying genetics. We used morphometric similarity analysis of MRI data as a marker of interareal cortical connectivity in three prior case–control studies of psychosis: in total, n =…

1h

Network cloning using DNA barcodes [Neuroscience]

The connections between neurons determine the computations performed by both artificial and biological neural networks. Recently, we have proposed SYNSeq, a method for converting the connectivity of a biological network into a form that can exploit the tremendous efficiencies of high-throughput DNA sequencing. In SYNSeq, each neuron is tagged with…

1h

Nanoscale imaging reveals miRNA-mediated control of functional states of dendritic spines [Neuroscience]

Dendritic spines are major loci of excitatory inputs and undergo activity-dependent structural changes that contribute to synaptic plasticity and memory formation. Despite the existence of various classification types of spines, how they arise and which molecular components trigger their structural plasticity remain elusive. microRNAs (miRNAs) have emerged as critical regulators…

1h

Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease [Neuroscience]

White matter abnormalities are a nearly universal pathological feature of neurodegenerative disorders including Huntington disease (HD). A long-held assumption is that this white matter pathology is simply a secondary outcome of the progressive neuronal loss that manifests with advancing disease. Using a mouse model of HD, here we show that…

1h

Partial inhibition of the overactivated Ku80-dependent DNA repair pathway rescues neurodegeneration in C9ORF72-ALS/FTD [Neuroscience]

GGGGCC (G4C2) repeat expansion in C9ORF72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). One class of major pathogenic molecules in C9ORF72-ALS/FTD is dipeptide repeat proteins such as poly(GR), whose toxicity has been well documented in cellular and animal models. However, it is…

1h

Gravitational instabilities in binary granular materials [Physics]

The motion and mixing of granular media are observed in several contexts in nature, often displaying striking similarities to liquids. Granular dynamics occur in geological phenomena and also enable technologies ranging from pharmaceuticals production to carbon capture. Here, we report the discovery of a family of gravitational instabilities in granular…

1h

From Bloch oscillations to many-body localization in clean interacting systems [Physics]

In this work we demonstrate that nonrandom mechanisms that lead to single-particle localization may also lead to many-body localization, even in the absence of disorder. In particular, we consider interacting spins and fermions in the presence of a linear potential. In the noninteracting limit, these models show the well-known Wannier–Stark…

1h

Competitive binding predicts nonlinear responses of olfactory receptors to complex mixtures [Physics]

In color vision, the quantitative rules for mixing lights to make a target color are well understood. By contrast, the rules for mixing odorants to make a target odor remain elusive. A solution to this problem in vision relied on characterizing receptor responses to different wavelengths of light and subsequently…

1h

DNA demethylation by ROS1a in rice vegetative cells promotes methylation in sperm [Plant Biology]

Epigenetic reprogramming is required for proper regulation of gene expression in eukaryotic organisms. In Arabidopsis, active DNA demethylation is crucial for seed viability, pollen function, and successful reproduction. The DEMETER (DME) DNA glycosylase initiates localized DNA demethylation in vegetative and central cells, so-called companion cells that are adjacent to sperm…

1h

Visual attention is not limited to the oculomotor range [Psychological and Cognitive Sciences]

Both patients with eye movement disorders and healthy participants whose oculomotor range had been experimentally reduced have been reported to show attentional deficits at locations unreachable by their eyes. Whereas previous studies were mainly based on the evaluation of reaction times, we measured visual sensitivity before saccadic eye movements and…

1h

MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis [Systems Biology]

Dysregulation of signaling pathways in multiple sclerosis (MS) can be analyzed by phosphoproteomics in peripheral blood mononuclear cells (PBMCs). We performed in vitro kinetic assays on PBMCs in 195 MS patients and 60 matched controls and quantified the phosphorylation of 17 kinases using xMAP assays. Phosphoprotein levels were tested for…

1h

Correction for Palmer, From water’s ephemeral dance, a new order emerges [Correction]

COMMENTARY Correction for “From water’s ephemeral dance, a new order emerges,” by Jeremy C. Palmer, which was first published February 5, 2019; 10.1073/pnas.1820940116 (Proc Natl Acad Sci USA 116:1829–1831). The author notes that on page 1829, right column, first paragraph, line 1, “characteristic rate of structural relaxation” should instead appear…

1h

Correction for Enos, Causal effect of intergroup contact on exclusionary attitudes [Correction]

POLITICAL SCIENCES Correction for “Causal effect of intergroup contact on exclusionary attitudes,” by Ryan D. Enos, which was first published February 24, 2014; 10.1073/pnas.1317670111 (Proc Natl Acad Sci USA 111:3699–3704). The author notes that, in Fig. 2 and Table 1, the second listed question appears incorrectly. It appeared as “Children…

1h

Correction for Ardesch et al., Evolutionary expansion of connectivity between multimodal association areas in the human brain compared with chimpanzees [Correction]

NEUROSCIENCE Correction for “Evolutionary expansion of connectivity between multimodal association areas in the human brain compared with chimpanzees,” by Dirk Jan Ardesch, Lianne H. Scholtens, Longchuan Li, Todd M. Preuss, James K. Rilling, and Martijn P. van den Heuvel, which was first published March 18, 2019; 10.1073/pnas.1818512116 (Proc Natl Acad…

1h

Correction to Supporting Information for Castle-Miller et al., Mechanisms regulating angiogenesis underlie seasonal control of pituitary function [SI Correction]

PHYSIOLOGY Correction to Supporting Information for “Mechanisms regulating angiogenesis underlie seasonal control of pituitary function,” by Jennifer Castle-Miller, David O. Bates, and Domingo J. Tortonese, which was first published March 7, 2017; 10.1073/pnas.1618917114 (Proc Natl Acad Sci USA 114:E2514–E2523). The authors wish to note the following: “The list of VEGF-A…

1h

How Donald Trump ruined a space art project

The Orbital Reflector should have been a celestial triumph. Until the US president and his government shutdown became involved Name: The Orbital Reflector. Age: Dead on arrival. Continue reading…

1h

Seed abortion and the role of RNA Pol IV in seed development

In this newly released article in The Plant Cell, researchers find that in Arabidopsis plants, the abortion of seeds with extra genomes is caused by the enzyme RNA Pol IV and the RNA-directed DNA methylation pathway, a major gene-silencing pathway in plants.

1h

Hell Is Other People’s Vacations

Luci Gutiérrez I f you feel like you need a vacation, you’re almost certainly right. Americans get far fewer paid days off than workers in pretty much any other industrialized democracy, and the time we actually take off has declined significantly, from 20.3 days in 1987 to 17.2 days in 2017. [ 1 ] Beyond souvenirs and suntans, the best reason to take a break may be your own health. For the Helsi

1h

Mother's Day gifts for the best moms you know

Gadgets You can't buy your mother's love, but presents are a pretty good way to say "thanks for helping me through my middle school years." You can't buy your mother's love, but presents are a pretty good way to say "thanks for helping me through my middle school years."…

1h

Let's watch Google announce new products and features at I/O 2019

Technology Android Q? Pixel 3 update? Let's find out what Google has coming up. Google is ready to show off what it's working on for 2019 and beyond.

1h

New England Biolabs® launches myNEB™, a first of its kind voice-activated digital lab assistant for Alexa

The new cloud-based service enables quick access to scientific information — including key restriction enzyme details — for molecular biologists in the lab.

1h

DRC expands Ebola vaccine campaign as cases mount rapidly

New strategies are deployed to slow spread of the deadly disease and better protect response teams

1h

Teaching CRISPR and antibiotic resistance to high school students

A team has developed BioBits, a suite of hands-on educational kits that enable students to perform a range of biological experiments by adding water and simple reagents to freeze-dried cell-free reactions.

1h

Nursing home cameras aim to protect the vulnerable but present ethical dilemmas

With reports of crimes against nursing home residents gaining media attention around the country, seven states have passed laws regulating the use of cameras in care facilities. An assistant professor in the University of Washington School of Social Work outlines the list of legal and moral issues that surveillance raises.

1h

Molekylen som återställer antibiotikans effekt mot tuberkulos

Omkring 1,5 miljoner människor dog av tuberkulos (TBC) år 2017, vilket gör den till den mest dödliga smittsamma sjukdomen världen över. Tuberkulos orsakas av bakterien Mycobacterium tuberculosis . En gång inuti kroppen förvandlas bakterierna till en tuffare form som tål mer stress och är svårare att döda. Dessutom är ökningen av läkemedelsresistent tuberkulos ett stort hinder för att behandla sju

1h

New treatment for severe dry eye disease promising in early clinical trials

Participants in a phase I/II clinical trial of a new enzyme-based treatment for severe dry eye disease experienced reduced signs of disease and discomfort, according to a new article.

1h

New 'jumping' superbug gene discovered, resistant to last-resort antibiotic

While sifting through the bacterial genome of salmonella, food scientists discovered mcr-9, a new stealthy, jumping gene so diabolical and robust that it resists one of the world's few last-resort antibiotics.

1h

Plastic gets a do-over: Breakthrough discovery recycles plastic from the inside out

Researchers have designed a recyclable plastic that, like a Lego playset, can be disassembled into its constituent parts at the molecular level, and then reassembled into a different shape, texture, and color again and again without loss of performance or quality.

1h

Health professionals wary of medicinal cannabis misuse and adverse effects

An analysis of published studies gauging attitudes to medicinal cannabis has found that while health professionals are broadly supportive, they feel they lack clinical and legislative knowledge, and their greatest concerns are the psychiatric harm that may be caused to patients and misuse by recreational drug users.

1h

Teaching CRISPR and antibiotic resistance to high school students

How can high school students learn about a technology as complex and abstract as CRISPR? It's simple: just add water.

1h

Space Sustainability Rating aims to address growing amount of space debris orbiting earth

The World Economic Forum has announced the introduction of a Space Sustainability Rating (SSR) system to help tackle the problem of space traffic and congestion in the Earth's orbit. The announcement of the SSR and the participating collaborators was made today at the Satellite 2019 conference in Washington, D.C.

1h

These amazing Met Gala looks took more than a thousand hours of 3D printing

Designer Zac Posen used additive manufacturing to create wearable sculptures for partygoers.

1h

Google expected to show off new hardware, AI at annual event

Google CEO Sundar Pichai is expected to showcase much-anticipated updates to the company's hardware lines and artificial intelligence Tuesday during his keynote at the company's annual I/O conference …

1h

Does insulin resistance cause fibromyalgia?

Researchers led by a team from The University of Texas Medical Branch at Galveston were able to dramatically reduce the pain of fibromyalgia patients with medication that targeted insulin resistance.

1h

Ocean activity is key controller of summer monsoons

New research from MIT finds ocean activity may control the strength and intensity of summer monsoons. The results could help researchers predict how monsoons will change with warming oceans.

1h

Nanoparticle Experiment Aboard ISS Seeks to Slow Aging

An ESA experiment that just arrived on the International Space Station (ISS) will test nanoparticles as a way to clear the body of free radicals. The post Nanoparticle Experiment Aboard ISS Seeks to Slow Aging appeared first on ExtremeTech .

2h

Teaching CRISPR and antibiotic resistance to high school students

How can high school students learn about a technology as complex and abstract as CRISPR? It's simple: just add water.

2h

Electoral regulations must tackle 'inequalities' caused by political advertising on Facebook

Regulators must find a way of monitoring and addressing the way political advertising on Facebook creates new types of inequalities for campaigners, experts have said.

2h

This global map of manure could help save farming as we know it

Plotting livestock poop could kick-start smarter phosphorus use

2h

Threatened sturgeon learns for the fitness

An international team is providing one of the first proofs of the complex learning behavior of fish in a recent study. The Atlantic sturgeon is thought to be locally extinct in Germany. Scientists are working toward sturgeon reintroduction and are investigating whether sturgeon training can increase their fitness for the wild. An important fitness factor is their feeding behavior. A two-week 'lear

2h

Teaching CRISPR and antibiotic resistance to high school students

A team has developed BioBits, a suite of hands-on educational kits that enable students to perform a range of biological experiments by adding water and simple reagents to freeze-dried cell-free reactions.

2h

Teen girls more vulnerable to bullying than boys

Girls are more often bullied than boys and are more likely to consider, plan, or attempt suicide, according to new research.

2h

Freshwater mussel shells were material of choice for prehistoric craftsmen

Researchers have discovered that 6000-years-ago people across Europe shared a cultural tradition of using freshwater mussel shells to craft ornaments.

2h

The evolution of skyrmions in multilayers and their topological Hall signature

The topological Hall effect (THE) is the Hall response to an emergent magnetic field, a manifestation of the skyrmion Berry-phase. As the magnitude of THE in magnetic multilayers is an open question, it is imperative to develop comprehensive understanding of skyrmions and other chiral textures, and their electrical fingerprint.

2h

Trump Fails the Betty Currie Test

Ralph Waldo Emerson once famously said that “a foolish consistency is the hobgoblin of little minds.” If so, then as a lawyer committed to the rule of law, I confess to having a little mind, though I like to think my consistency is not foolish. Earlier this week, I signed a letter (along with a growing number—now more than 600—of other former federal prosecutors) expressing the view that the fact

2h

Court Orders EPA to Address Landfill Emissions

Waste dumps are the third-largest emitters of methane in the U.S. and release other harmful pollutants — Read more on ScientificAmerican.com

2h

Markets missing fossil fuel exposure to climate risk: analysis

Investors are overlooking the long-term risks climate change poses to oil and gas infrastructure firms, which face tens of billion of dollars worth of stranded assets as the world transitions to greener energy, according to new analysis seen by AFP.

2h

Montmorency tart cherries may provide benefits for adults with metabolic syndrome

Montmorency tart cherries reduced systolic blood pressure, insulin levels and insulin concentrations in adults with metabolic syndrome participating in a small pilot study published in the Journal of Functional Foods.

2h

New treatment for severe dry eye disease promising in early clinical trials

Participants in a phase I/II clinical trial of a new enzyme-based treatment for severe dry eye disease experienced reduced signs of disease and discomfort, according to a paper in Translational Vision Science and Technology.

2h

Colorado nail salon workers face chronic air pollution, elevated cancer risk

Colorado nail salon employees face increased health risks due to high levels of indoor airborne pollutants such as formaldehyde and benzene, new University of Colorado Boulder research finds, concluding that working in a salon is akin to working at an oil refinery or an auto garage.

2h

Essential tool for precision farming: new method for photochemical reflectance index measurement

Precision farming, which relies on spatially heterogeneous application of fertilizers, biologically active compounds, pesticides, etc., is one of the leading trends in modern agricultural science.

2h

Teaching CRISPR and antibiotic resistance to high school students

A Northwestern University-led team has developed BioBits, a suite of hands-on educational kits that enable students to perform a range of biological experiments by adding water and simple reagents to freeze-dried cell-free reactions.

2h

Oxygen variation controls episodic pattern of Cambrian explosion: study

A multidisciplinary study, published on May 6, 2019 in Nature Geoscience by a joint China-UK-Russia research team, gives strong support to the hypothesis that the oxygen content of the atmosphere and ocean was the principal controlling factor in early animal evolution.

2h

Alexa for Windows 10 PCs goes hands-free

In November, Amazon launched an Alexa app for Windows 10 PCs which allowed PC owners to speak to Alexa in order to set reminders, timers, alarms, create to-dos, track their calendar, control …

2h

First-Ever Video Shows Immune System Blowing Holes in Bacteria

A microscopic video of the human immune system in action reveals how our bodies blow tiny holes in foreign bacteria, while leaving our own cells intact

2h

The Deeper Dilemma for Daenerys in Game of Thrones

This article contains spoilers for Game of Thrones Season 8, Episode 4 . As Tyrion and Varys debated whether to turn on the queen they serve in the most recent episode of Game of Thrones , one of them made clear that Daenerys Targaryen is not his ultimate boss. Something more abstract is. “You know where my loyalty stands,” Varys told Tyrion. “You know I will never betray the realm.” “What is the

2h

Health and Human Services and the Religious-Liberty War

For almost a decade, a battle over religious liberty, abortion, and LGBTQ medical care has been playing out dramatically in the U.S. Department of Health and Human Services. Religious conservatives, who are predominantly Christian and have enormous sway in the Trump administration, have fought to protect their beliefs and practices, which often compel them not to participate in abortion and life-

2h

Raise taxes on firms that harm nature, OECD tells G7 countries

Report calls for change of priorities and culture to avert catastrophic biodiversity loss Governments need to ramp up investment in nature restoration and raise the tax burden on companies that degrade wildlife, according to recommendations made to the G7 group of rich nations. The proposals are part of a growing debate on how to radically change humanity’s relationship with nature in the wake of

2h

Southern African leaders seek ways to manage elephant populations

Leaders from four southern African countries held talks in Botswana on Tuesday to better manage the world's largest concentration of elephants, amid growing concerns over poaching, loss of habitat, and conflict with humans.

2h

Academics show how to create a spotlight of sound with LEGO-like bricks

Informatics experts create low-cost directional beams of sound. Using age-old principles of magnifying glasses, lighthouses and telescopes to create state-of-the-art sound. Bringing the vision of Minority Report into reality and transforming possibilities of entertainment industry.

2h

Tibetan plateau first occupied by middle Pleistocene Denisovans

A joint research team led by CHEN Fahu from the Institute of Tibetan Plateau Research of the Chinese Academy of Sciences and ZHANG Dongju from the Lanzhou University reported their studies on a human mandible found in Xiahe, on the Northeastern Tibetan Plateau.

2h

Research clarifies role of posterior parietal cortex in decision-making

Researchers at the Institute of Neuroscience of the Chinese Academy of Sciences provided new insights into the functional role of the PPC in decision-making. They obtained compelling evidence to show that the posterior parietal cortex (PPC) indeed plays an essential role in decision-making under critical conditions that were largely ignored in previous studies.

2h

Threatened sturgeon learns for the fitness

An international team led by IGB is providing one of the first proofs of the complex learning behavior of fish in a recent study. The Atlantic sturgeon is considered extinct in Germany. The IGB is coordinating their reintroduction and is investigating whether sturgeon training can increase their fitness for the wild. An important fitness factor is their feeding behavior. Already a two-week 'learni

2h

When doctors and nurses can disclose and discuss errors, hospital mortality rates decline

The diffusion of a culture of openness in hospitals is associated with lower hospital mortality, according to a study conducted among 137 acute trusts in England by Veronica Toffolutti (Bocconi University and London School of Hygiene & Tropical Medicine) and David Stuckler (Bocconi University). A one-point increase in their standardized openness score is associated with a 6.48% decrease in hospita

2h

Patients of medicare providers committing fraud, abuse more likely to be poor, disabled

A new study from the Johns Hopkins Bloomberg School of Public Health analyzed providers excluded from Medicare for fraud and abuse, and found that the patients they treated prior to being banned were more likely to be minorities, disabled and dually-enrolled in Medicaid to supplement financial assistance for health care.

2h

Biophysicists resolve true structure of highly promising optogenetic protein KR2 rhodopsin

A team of biophysicists has discovered and studied the structure of the KR2 rhodopsin under physiological conditions. This pioneering work breaks ground for a future breakthrough in optogenetics, a highly relevant area of biomedicine with applications in neurological disease treatment and more. The fundamental discovery will lead to a new instrument for efficient therapy of depression, anxiety dis

2h

3D 'mini-gut' model reflects autoimmune response to gluten in celiac patient tissue

In pursuit of a novel tool for the research and treatment of celiac disease, scientists at the Mucosal Immunology and Biology Research Center at Massachusetts General Hospital have validated the use of intestinal organoids.

2h

New 'jumping' superbug gene discovered, resistant to last-resort antibiotic

While sifting through the bacterial genome of salmonella, Cornell University food scientists discovered mcr-9, a new stealthy, jumping gene so diabolical and robust that it resists one of the world's few last-resort antibiotics.

2h

New Class II Biological Safety Cabinets Deliver Superior Performance for Product, Personnel and Environmental Protection

The Thermo Scientific Herasafe and Maxisafe 2030i BSCs offer optimal contamination prevention, data management and ergonomics

2h

Duking It Out with Quantum Mechanics

A longtime professor of astronomy continues to wrestle with the strangeness of it all — Read more on ScientificAmerican.com

2h

Global renewables growth has stalled—and that’s terrible news

Additions of wind, solar, hydro, and other clean energy sources have unexpectedly flattened after two decades of reliable gains.

2h

Duking It Out with Quantum Mechanics

A longtime professor of astronomy continues to wrestle with the strangeness of it all — Read more on ScientificAmerican.com

2h

Three lions rescued in Albania sent to the Netherlands

Three lions, rescued in October from a private zoo in Albania where they were kept in "hellish" conditions were transported Tuesday to the Netherlands, an animal welfare organisation said.

2h

Strike set for rideshare drivers, casting shadow on Uber IPO

Rideshare drivers in major US cities were set to strike Wednesday, casting a shadow over the keenly anticipated Wall Street debut of sector leader Uber.

2h

Southern African leaders seek ways to manage elephant populations

Leaders from four southern African countries held talks in Botswana on Tuesday to better manage the world's largest concentration of elephants, amid growing concerns over poaching, loss of habitat, and conflict with humans.

2h

Three lions rescued in Albania sent to the Netherlands

Three lions, rescued in October from a private zoo in Albania where they were kept in "hellish" conditions were transported Tuesday to the Netherlands, an animal welfare organisation said.

2h

En miljon arter hotas av utrotning

Mine Islar, forskare vid Lund University Centre for Sustainabilty Studies, vad är det mest intressanta i rapporten? 1. Att förlusten av biologisk mångfald är lika avgörande som klimatförändringarna. Förlusten av arter, hela ekosystem och genetisk mångfald är redan ett globalt hot och ett generationshot mot mänskligt välbefinnande. Många av våra basala behov, som livsmedelsproduktion, matsäkerhet

2h

Specific People Are Weirdly Good at Predicting the Future

Fortune Tellers If a world-renowned expert makes a prediction about the future, there’s a good chance that they’ll be wrong. Historically, scientific evidence suggests that the people best suited to predict future world events are generalists who dabble in all sorts of fields, according to a fascinating new book excerpt in The Atlantic , because they’re less beholden to their own biases. On the o

2h

2h

Watch how this video brilliantly compares planet sizes

A video imagines what if the planets were all the same distance from Earth as the moon. The largest planets like Jupiter and Saturn would loom large in the sky. Mercury is the smallest planet in the solar system. None A graphic published on Twitter brings out the relative sizes of planets into perspective by imagining – what if the planets were as far from us as the moon? Here's how that would lo

2h

Australia’s Politics May Be Changing With Its Climate

Australia feels the brunt of climate change. Now, as elections approach, its politicians are trying to figure out how to manage the anxiety of voters.

2h

A Decades-Old Doctor’s Secret Leads to New Fertility-Fraud Law

In 2014, 23andMe tests revealed a decades-old secret in Indianapolis: A local fertility doctor named Donald Cline had secretly used his own sperm to impregnate his patients in the 1980s . As the popularity of DNA tests grew over the next few years, so did the count of his known biological children. They now number more than 50. And they have all learned—to their surprise—that no law in Indiana sp

2h

Trump’s Grievances Are His Governing Agenda

It was a meeting about maritime shipping, but President Donald Trump had other things on his mind. As he spoke privately with Republican lawmakers in the White House’s Roosevelt Room, Attorney General William Barr was all over TV testifying to a Senate committee about the Russia investigation. Trump had been watching the live coverage, he’d been briefed on Barr’s testimony—and sitting with his gu

2h

The Guy Who Bought a SpaceX Ticket to the Moon Is Broke

State of the Art In October, Yusaku Maezawa slapped down what Elon Musk called a “significant deposit” to be SpaceX’s first Moon passenger. Right about now, though, the Japanese fashion tycoon might be wondering if that deposit was refundable. On Sunday, Maezawa announced he’d be auctioning off several pieces from his personal art collection this month, later tweeting , “Yes, I have no money” — a

2h

Arctic rivers provide fingerprint of carbon release from thawing permafrost

The feedback between a warming climate and accelerated release of carbon currently frozen into permafrost around the Arctic is one of the grand challenges in current climate research. A study used radiocarbon dating of carbon in four large Siberian-Arctic rivers to pinpoint the patterns of old carbon release from permafrost across northern Eurasia.

2h

Vaccine for African swine fever may save our bacon

Wild boar can be immunized against African Swine Fever by a new vaccine delivered to the animals in their food. This is the first report of a promising inoculation against this deadly disease, which is a worldwide threat to the swine industry. The study shows immunity can be passed on via contact, but further studies need to examine how this occurs, the safety of repeated administration and its ge

2h

New material also reveals new quasiparticles

Researchers have investigated a novel crystalline material that exhibits electronic properties that have never been seen before. It is a crystal of aluminum and platinum atoms arranged in a special way. This resulted in novel properties of electronic behavior for the crystal as a whole, including so-called Rarita-Schwinger fermions in its interior.

2h

A novel method for improving imaging techniques in geophysical and material studies

One of the remarkable aspects of science is its ability to extend our sense of perception beyond touch and sight, often using the information provided by the "scattering" of waves. A group of researchers working on the "inverse scattering" problem has pushed the scope of this. They have developed a method for identifying the location of point-like scatterers based on fluctuations in the physical p

2h

Video brilliantly compares planet sizes

A video imagines what if the planets were all the same distance from Earth as the moon. The largest planets like Jupiter and Saturn would loom large in the sky. Mercury is the smallest planet in the solar system. None A graphic published on social media brings out the relative sizes of planets into perspective by imagining – what if the planets were as far from us as the moon? Here's how that wou

2h

Black academics publish one-fifth of South Africa’s research

Black academics publish one-fifth of South Africa’s research Black academics publish one-fifth of South Africa’s research, Published online: 07 May 2019; doi:10.1038/d41586-019-01446-6 But academia and publishing remains disproportionally white in wake of apartheid.

2h

Scientists Turn Atmospheric CO2 Into Coal

submitted by /u/inFAM1S [link] [comments]

2h

New Progress in the Biggest Challenge With 3D Printed Organs

submitted by /u/dwaxe [link] [comments]

2h

2h

2h

New plastic material can be recycled again and again

submitted by /u/redkemper [link] [comments]

2h

Ancient Greek method for finding prime numbers just got an upgrade

A new algorithm improves on an ancient Greek method for finding prime numbers known as the sieve of Eratosthenes

2h

Everyday stress may boost blood vessel dysfunction in people with depression

Long-term stress has been linked with cardiovascular disease, but for people with depression, researchers say small, everyday stressors may be enough to diminish blood vessel function in otherwise healthy adults.

3h

Eye for Manipulation: A Profile of Elisabeth Bik

The microbiologist has turned her attention full-time to unearthing problematic figures in papers–for free.

3h

Why Met Gala Attendees Always Screw Up the Theme

For New York City’s wealthiest inhabitants, the advent of spring means gala season: a string of fancy, expensive parties benefiting museums, cultural institutions such as the ballet, and other charitable causes. Every year, the season hits its crescendo on the first Monday in May, with the Metropolitan Museum of Art’s Costume Institute Gala. The party is the toughest ticket in town, with a more o

3h

The U.S.-China Trade Talks Have Already Changed the World

Robert Lighthizer, the U.S. trade representative, is no one’s idea of an optimist. He and Treasury Secretary Steven Mnuchin have been leading trade talks with China for the past several months, and Lighthizer has been careful to point out there’s no guarantee of success. “If there’s a great deal to be gotten, we’ll get it —if not, we’ll find another plan,” Lighthizer told NPR recently. That’s a l

3h

Stem cells make more 'cargo' packets to carry cellular aging therapies

Scientists report that adult cells reprogrammed to become primitive stem cells, called induced pluripotent stem cells (iPSCs), make tiny 'cargo packets' able to deliver potentially restorative or repairing proteins, antibodies or other therapies to aged cells. They say the human iPSCs they studied produced much more of the packets, formally known as extracellular vesicles, than other kinds of adul

3h

Alternative treatment for epileptic seizures in children identified

A new study has identified a 'user friendly' treatment for the most common life-threatening neurological emergency in children.

3h

Close relatives can coexist: two flower species show us how

Scientists have discovered how two closely-related species of Asiatic dayflower can coexist in the wild despite their competitive relationship. Through a combination of field surveys and artificial pollination experiments, the new study shows that while reproductive interference exists between the two species, both can counter the negative effects of this interference through self-fertilization.

3h

Academics show how to create a spotlight of sound with LEGO-like bricks

Informatics experts create low-cost directional beams of sound. Using age-old principles of magnifying glasses, lighthouses and telescopes to create state-of-the-art sound. Bringing the vision of Minority Report into reality and transforming possibilities of entertainment industry.

3h

Locking Eyes With a Monster

Staring at somebody’s face for ten minutes may give you nightmares — Read more on ScientificAmerican.com

3h

Teslas Can Now Detect Broken Parts and Pre-Order Replacements

Self-Healing A new update pushed to Tesla vehicles includes a “live issue detection” feature, which enables them to “keep tabs on certain components to let you know if they need replacing and order parts ahead of your next service visit,” according to a company statement sent to Electrek . Once the vehicle figures out which replacement part it needs, it pre-orders it to the closest Tesla Service

3h

Signalanalys upptäcker korta flimmerattacker

Omkring tre procent av landets vuxna drabbas av förmaksflimmer, vilket är en betydande riskfaktor för stroke. För 80-åringar är siffran över 15 procent. Därför är undersökningar av vem som har flimmer livsviktiga. Förmaksflimmer är en heterogen sjukdom som varierar från patient till patient. Mikael Henrikssons, forskare vid Lunds tekniska högskola visar i sin avhandling i biomedicinsk teknik hur

3h

Electoral regulations must tackle 'inequalities' caused by political advertising on Facebook

Regulators must find a way of monitoring and addressing the way political advertising on Facebook creates new types of inequalities for campaigners, experts have said.

3h

Eye's vulnerability to macular degeneration revealed

Scientists have found significant differences in the shape and biology of the same type of cell taken from different parts of the retina, according to a study in eLife.

3h

Challenging metabolism may help fight disease

New research by Swansea University academics has shown that harnessing metabolism at a cellular level may help to relieve or heal a range of disorders.

3h

Arsenic in drinking water may change heart structure raising risk of heart disease

Drinking water that is contaminated with arsenic may lead to thickening of the heart's main pumping chamber in young adults, according to a new study by researchers at Columbia University Mailman School of Public Health. This structural change increases the risk for future heart problems. The study is the first to review the question in young adults.

3h

Researchers uncover mechanism blocking retina regeneration

A discovery opens the possibility of one day restoring loss of vision by activating the retina's ability to regenerate. Researchers have discovered that the mammalian retina, although it does not spontaneously regenerate, has a regenerative capacity that is kept dormant by a cellular mechanism called the Hippo pathway.

3h

Damaged lungs regenerated in study

A new technique to rehabilitate lungs that are too damaged to be considered for transplant could benefit an increasing population of patients with end-stage lung disease.

3h

New approach shows regeneration of severely damaged lungs

Researchers have — for the first time — demonstrated in a clinically relevant model that severely damaged lungs can be regenerated to meet transplantation criteria. Their new study describes the cross-circulation platform that maintained the donor lung's viability and function and the recipient's stability for 36-56 hours. Current methodologies of lung support are limited to only 6-8 hours, a ti

3h

Success tastes so sweet

Researchers from the National Institute for Physiological Sciences characterized the role of neurons in the parabrachial nucleus of mice, which is known to relay taste information to the cortex via the gustatory thalamus. SatB2-expressing neurons encoded sweet tastes, and this was especially true for those that projected to the gustatory thalamus. SatB2-expressing neurons selectively transmitted s

3h

Scientists pinpoint potential new target for regulating inflammation

The scientists discovered that an ancient protein (SARM) is a key regulator of inflammasomes — tiny molecular machines that initiate the inflammatory response. If they can successfully target SARM, they may be able to better control the inflammation that is a factor in a host of diseases including diabetes, cancer, and Alzheimer's.

3h

How common is alcoholic fatty liver disease?

This study used national survey data from 2001-2016 to examine how common alcoholic fatty liver disease is in the United States.

3h

Association between weight before pregnancy, weight gain during pregnancy and adverse outcomes for mother, infant

An analysis that combined the results of 25 studies including nearly 197,000 women suggests prepregnancy body mass index (BMI) of the mother was more strongly associated with risk of adverse maternal and infant outcomes than the amount of gestational weight gain.

3h

Aspirin before at-home colorectal cancer screening test didn't significantly improve ability to detect cancer precursors

Some observational studies have suggested that taking aspirin before undergoing colorectal cancer screening with a fecal immunochemical test for blood in stool might improve the ability of the test to detect cancer precursors.

3h

Why visual stimulation may work against Alzheimer's

MIT neuroscientists have found that using flickering light to stimulate gamma oscillations in the brain has widespread effects on neurons and immune cells called microglia. This treatment reduces inflammation, enhances synaptic function, and protects against cell death in mice that are genetically programmed to develop Alzheimer's disease.

3h

Fat fruit flies: High-sugar diet deadens sweet tooth; promotes overeating, obesity in flies

Some research suggests that one reason people with obesity overeat is because they don't enjoy food — especially sweets — as much as lean people.

3h

Lions vs. porcupines

Lions can bring down wildebeests and giraffes, but when they try to hunt porcupines, the spiky rodents often come out on top. When lions attack porcupines (it's usually young male lions that make that mistake), the porcupine's spines can seriously injure the lion. These injuries can make it impossible for the lions to hunt normally, leading them to hunt livestock or even humans. This study is a de

3h

Key step in transformation of B cells to antibody-secreting cells described

Immunologist Frances Lund, Ph.D., and colleagues have detailed the role of a key controlling factor in the transformation of B cells into antibody-secreting cells, the cells that produce antibodies to fight invading pathogens like viruses. The key controlling factor also is needed for memory B cells to respond to a second, subsequent infection by a pathogen.

3h

This new T. rex relative weighed less than 100 pounds

Researchers have uncovered much of the skull and skeleton of a small tyrannosaur from Late Cretaceous rocks in New Mexico. Tyrannosauroid dinosaurs have a long evolutionary history and include iconic giants like Tyrannosaurus rex . This newly discovered species links the small tyrannosauroids from the Early Cretaceous of North America and China with much larger ones that survived until the end of

3h

Cats 'Farm' Bacteria in Their Butts. Here's Why.

Cat butts are home to communities of microbes that produce cats' distinctive, stinky pheromone spray.

3h

Regeneration of severely damaged lungs using an interventional cross-circulation platform

Regeneration of severely damaged lungs using an interventional cross-circulation platform Regeneration of severely damaged lungs using an interventional cross-circulation platform, Published online: 07 May 2019; doi:10.1038/s41467-019-09908-1 Gastric aspiration severely injures donor lungs, frequently making them unacceptable for transplantation. Here the authors show that an interventional cross

3h

PlayStation 4 owners can take advantage of EA Access starting this summer

On Tuesday, EA announced it is bringing its EA Access subscription service to the PlayStation 4. It has already been available on PC and Xbox since 2014. Membership in EA Access provides a few …

3h

Antimatter Acts Like Regular Matter in Classic Double Slit Experiment

(Inside Science) — One of the strangest things about quantum mechanics is that a particle can act like a wave. In particular, in a double-slit experiment, individual particles that are shot through a pair of slits create a pattern as if they each went through both slits simultaneously and interfered with themselves. Researchers have now shown for the first time that antimatter behaves in the same

3h

Game of Thrones Is Considering ‘Electability.’ It Isn’t Going Well.

This story contains spoilers through Season 8, Episode 4 of Game of Thrones. An early scene in “The Last of the Starks,” the latest episode of Game of Thrones , finds Jon Snow giving a speech to the survivors of the Battle of Winterfell as the weary warriors prepare to burn the bodies of those who have fallen. “We’re here to say goodbye to our brothers and sisters, to our fathers and mothers—to o

3h

What kids learn in school can sway their parents’ beliefs

Environment Teaching children about the reality of global warming may be one more way to convince folks. It’s perhaps a testament to the power of parent-child trust. Whereas a conservative parent may be inclined to see a liberal politician or a climate scientist as a threat…

3h

How birdwatchers can help threatened bird populations

The types of birds coming through your neighborhood are probably changing, and so is the timing of their migrations. Birdwatchers noticing these differences are on the front line in figuring out how climate change and more severe weather events are putting stress on bird populations.

3h

How birdwatchers can help threatened bird populations

The types of birds coming through your neighborhood are probably changing, and so is the timing of their migrations. Birdwatchers noticing these differences are on the front line in figuring out how climate change and more severe weather events are putting stress on bird populations.

3h

US climate objections sink Arctic Council accord in Finland

There is no joint declaration by Arctic nations as the US criticises climate change wording.

3h

New Progress in the Biggest Challenge With 3D Printed Organs

We’re tantalizingly close to growing organs in the lab, but the biggest remaining challenge has been creating the fine networks of blood vessels required to keep them alive. Now researchers have shown that a common food dye could solve the problem. In the US there are currently more than 100,000 people on organ transplant waiting lists. Even if you’re lucky enough to receive a replacement, you fa

3h

This Space Extinguisher Can Vacuum Up Flames

Fire! Fire! Fighting open fire in the microgravity of space is terrifyingly different than back on Earth — but researchers at the Toyohashi University of Technology in Japan say they’ve found a clever solution: a space fire extinguisher that sucks up the blaze like a vacuum cleaner. “Our proposed extinguisher can allow us the immediate fire-fighting without oxygen mask and could avoid the post-tr

3h

Off the Coast of Portugal, the Earth's Crust Might Be Peeling in Two

It might explain the massive earthquake of 1755 which destroyed the city of Lisbon

3h

Patients insured by marketplace health plan less likely to receive a medical appointment

Among adults with mental health needs, those covered by Medicare or employer-sponsored health insurance have greater access to medical treatment, less out-of-pocket cost and are more likely to receive care than those seeking an appointment through an Affordable Care Act (ACA) Marketplace-sponsored plan, according to findings from researchers at Drexel University's Dornsife School of Public Health.

3h

Electroconvulsive therapy reboots certain brain networks to help depressed individuals

Electroconvulsive therapy (ECT) helps people with severe depression by 'pushing the reset button' on brain networks involved in creating a mental picture, according to recent Baycrest findings.

3h

Teen girls more vulnerable to bullying than boys

Girls are more often bullied than boys and are more likely to consider, plan, or attempt suicide, according to research led by a Rutgers University-Camden nursing scholar. 'Bullying is significantly associated with depressive symptoms, suicidal ideation, suicide planning, and suicide attempts,' says Nancy Pontes, an assistant professor at the Rutgers School of Nursing-Camden. 'We wanted to look at

3h

Fat fruit flies: High-sugar diet deadens sweet tooth; promotes overeating, obesity in flies

Some research suggests that one reason people with obesity overeat is because they don't enjoy food—especially sweets—as much as lean people.

3h

Fat fruit flies: High-sugar diet deadens sweet tooth; promotes overeating, obesity in flies

Some research suggests that one reason people with obesity overeat is because they don't enjoy food—especially sweets—as much as lean people.

3h

Lions vs. porcupines—Historical records show what leads lions to hunt porcupines and what happens when they do

Not much can mess with a lion. They're four-hundred-pound top predators, bringing down large prey like wildebeests, zebras, and even giraffes. But they're not invincible—a new study delves into the interactions between lions and porcupines, and shows how these spiky, cocker spaniel-sized critters can come out on top.

3h

How to revive your belief in democracy | Eric Liu

Civic evangelist Eric Liu shares a powerful way to rekindle the spirit of citizenship and the belief that democracy still works. Join him for a trip to "Civic Saturday" and learn more about how making civic engagement a weekly habit can help build communities based on shared values and a path to belonging.

3h

Asteroid incoming, Bruce Willis little help

NASA-organised war-gaming on Armageddon scenario reveals complexity, complications, and deep concern. Richard A Lovett reports.

3h

Lion attacks porcupine. Porcupine wins

When times are tough, lions will eat porcupines. Researchers find it’s not a case of good quill hunting. Tanya Loos reports.

3h

The Saga’s Crane Breaks Loose | Deadliest Catch

In the biggest storm of the season, Jake and the Saga crew must address a loose forward crane that’s swinging out of control. Stream Full Episodes of Deadliest Catch: https://www.discovery.com/tv-shows/deadliest-catch/ Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Join us on Facebook: https://www.facebook.com/DeadliestCatch https://www.facebook.com/Discovery Follow us on Twitter: https

3h

Science Says: Why biodiversity matters to you

You may go your entire life without seeing an endangered species, yet the globe's biodiversity crisis threatens all of humanity in numerous unseen or unrecognized ways, scientists say.

3h

Lions vs. porcupines—Historical records show what leads lions to hunt porcupines and what happens when they do

Not much can mess with a lion. They're four-hundred-pound top predators, bringing down large prey like wildebeests, zebras, and even giraffes. But they're not invincible—a new study delves into the interactions between lions and porcupines, and shows how these spiky, cocker spaniel-sized critters can come out on top.

3h

America may outsmart China in 5G with AI and blockchains

An FCC commissioner hopes that machine learning and distributed crypto-ledgers will free up wireless spectrum for billions of devices.

3h

The Subtle Art of the Mathematical Conjecture

Mountain climbing is a beloved metaphor for mathematical research. The comparison is almost inevitable: The frozen world, the cold thin air and the implacable harshness of mountaineering reflect the unforgiving landscape of numbers, formulas and theorems. And just as a climber pits his abilities against an unyielding object — in his case, a sheer wall of stone — a mathematician often finds hersel

3h

Ethiopian clothes makers worst paid in the world: study

Ethiopia's clothes factory workers, producing items for top fashion brands including Guess, H&M and Calvin Klein, are the worst paid in the world, earning only $26 (23 euros) a month, a report said Tuesday.

3h

Academics show how to create a spotlight of sound with LEGO-like bricks

Academics have created devices capable of manipulating sound in the same way as light—creating exciting new opportunities in entertainment and public communication.

3h

Vaccine for African swine fever may save our bacon

Wild boar can be immunized against African Swine Fever by a new vaccine delivered to the animals in their food, says new research. Published in Frontiers in Veterinary Science, it is the first report of a promising inoculation against this deadly disease, which is a worldwide threat to the swine industry. The study also provides evidence that this immunity can be passed on via contact with immuniz

3h

New species of fish parasite named after Xena, the warrior princess

A study of parasitic crustaceans attaching themselves inside the branchial cavities (the gills) of their fish hosts was recently conducted in order to reveal potentially unrecognised diversity of the genus Elthusa in South Africa.

3h

Vaccine for African swine fever may save our bacon

Wild boar can be immunized against African Swine Fever by a new vaccine delivered to the animals in their food, says new research. Published in Frontiers in Veterinary Science, it is the first report of a promising inoculation against this deadly disease, which is a worldwide threat to the swine industry. The study also provides evidence that this immunity can be passed on via contact with immuniz

3h

New species of fish parasite named after Xena, the warrior princess

A study of parasitic crustaceans attaching themselves inside the branchial cavities (the gills) of their fish hosts was recently conducted in order to reveal potentially unrecognised diversity of the genus Elthusa in South Africa.

3h

Researchers discover a trigger for directed cell motion

Researchers at the Cells-in-Motion Cluster of Excellence at Münster University (Germany) have discovered that curvatures of cell membranes trigger a self-organising system. As a result, cells can move in the same direction over a longer distance, forming search patterns. The study has been published in the journal 'Nature Physics'.

3h

Dehesa health starts from the ground up

University of Cordoba research analyzes how changes in the structure of soil microbiota affect holm oak decline.

3h

A study analyzes the academic repercussions of institutional scientific dissemination

Communicating research results to the public generates a range of positive effects on the careers of university professors, according to a study carried out by researchers at Universidad Carlos III de Madrid (UC3M) and the Universidad de Valencia (UV), which analyzed the perception of university researchers who have participated in institutional communication campaigns.

3h

A novel method for improving imaging techniques in geophysical and material studies

The Department of Civil Engineering, led by Prof. Terumi Touhei, at Tokyo University of Science has developed a novel mathematical method for reconstruction/imaging of the complex distribution of point-like scatterers using a sensor grid with a small network. This method can potentially be used to improve the efficiency of tomography in underground geophysical studies, nondestructive physical test

3h

Arctic rivers provide fingerprint of carbon release from thawing permafrost

The feedback between a warming climate and accelerated release of carbon currently frozen into permafrost around the Arctic is one of the grand challenges in current climate research. A study published this week in the Proceedings of the National Academy of Sciences of the USA by a team of researchers led by Stockholm University used radiocarbon dating of carbon in four large Siberian-Arctic river

3h

ATLAS Experiment adds more pieces to the Higgs boson puzzle

The Higgs boson was discovered in 2012 by the ATLAS and CMS Experiments at CERN, but its coupling to other particles remains a puzzle.

4h

Engineered 'smart cells' improve production of pharmaceutical raw materials

Researchers in Japan have developed an integrated synthetic biology system to construct new metabolic pathways and enzymes within microbes. By incorporating a "Design, Build, Test, Learn" (DBTL) workflow, the production of pharmaceutical raw materials could be systematically optimized. This application supports the concept of the DBTL workflow as a sustainable method for production of complex and

4h

Analysis of remains in ancient gravesite gives insight into Neolithic history in Poland

A large team of researchers from across Europe and the U.K. has learned more about Neolithic history in Poland by studying the remains of people buried in a mass grave in a southern part of the country. In their paper published in Proceedings of the National Academy of Sciences, the group describes the results of DNA testing they conducted on the remains and what they found.

4h

Five tips on how to be a good mentor to someone twice your age

Plato and Aristotle. Barbara Walters and Oprah Winfrey. Steve Jobs and Mark Zuckerberg. In each of these famous relationships it was the older person with more experience acting as mentor, guiding the much younger "mentee" in their career.

4h

Støj på kontoret og i trafikken kan gøre dig alvorligt syg

Forskning viser, at støj øger risikoen for kræft, diabetes og hjerte-kar-sygdomme.

4h

4h

4h

4h

4h

Andrew Yang talks carbon removal and geoengineering

submitted by /u/DragonGod2718 [link] [comments]

4h

1,5 grader eller varmare? EU-rösterna avgör ambitionsnivån

– Tyvärr lever vi i en tid där klimatförändringen har blivit en politisk fråga, men det är fortfarande viktigt att se det som ett kollektivt problem. Där är EU ett strålande exempel på enad kollaboration. Jag tror att EU är vår bästa chans att organisera ett svar som motsvarar folkets kollektiva vilja, säger Keith Larson, evolutionär ekolog vid Climate Impacts Research Centre vid Umeå universitet

4h

Academics show how to create a spotlight of sound with LEGO-like bricks

Informatics experts create low-cost directional beams of sound. Using age-old principles of magnifying glasses, lighthouses and telescopes to create state-of-the-art sound. Bringing the vision of Minority Report into reality and transforming possibilities of entertainment industry

4h

Alternative treatment for epileptic seizures in children identified

A new study published in The Lancet, involving researchers from the University of Liverpool and Alder Hey Children's Hospital Trust, has identified a 'user friendly' treatment for the most common life-threatening neurological emergency in children.

4h

Stem cells make more 'cargo' packets to carry cellular aging therapies

Johns Hopkins scientists report that adult cells reprogrammed to become primitive stem cells, called induced pluripotent stem cells (iPSCs), make tiny 'cargo packets' able to deliver potentially restorative or repairing proteins, antibodies or other therapies to aged cells. They say the human iPSCs they studied produced much more of the packets, formally known as extracellular vesicles, than other

4h

Novel artificial intelligence method predicts future risk of breast cancer

Researchers from two major institutions have developed a new tool with advanced artificial intelligence (AI) methods to predict a woman's future risk of breast cancer, according to a new study.

4h

Ny aftale: Landstrømsanlæg skal nedsætte krydstogt-os

Efter årelangt pres vælger Københavns Kommune at fokusere på at nedbringe den omfattende forurening fra krydstogtskibe.

4h

GM Cruise autonomous vehicle unit gets $1.15B investment

A group of institutional investors is sinking $1.15 billion into GM Cruise LLC, the autonomous vehicle unit of General Motors.

4h

Climate refugee fish take shelter in shipwrecks

Warming oceans may lead even more tropical and subtropical fish to take up residence in shipwrecks off the North Carolina coast, research finds. “The artificial reefs created by these structures may be acting as stepping stones for fish that are moving northward and living at the edge of their geographic range, or beyond it, in search of suitable habitat,” says lead author Avery B. Paxton, a visi

4h

What Facebook Could Have Been

Let me tell you about the time I invented Facebook. It was 2002, after my second child was born. It had been difficult to keep friends and family up to date with my first, and in the short time between them almost everyone had gone online—friends, parents, even grandparents. I was working professionally as a web developer, so I did what came naturally: I built a website. I didn’t really invent Fa

4h

Sparkle and spiral

Hubble captures the visual splendour of a distant galaxy.

4h

GM Cruise autonomous vehicle unit gets $1.15B investment

A group of institutional investors is sinking $1.15 billion into GM Cruise LLC, the autonomous vehicle unit of General Motors.

4h

The deadly, life-giving and transient elements that make up group 15 of the periodic table

When you see the periodic table, what comes to mind? The pieces on a scrabble board? Maybe you think about your high school chemistry class. Maybe you think of the colorful table plastered on the wall of a lecture hall in college. Maybe you remember your favorite teacher setting something on fire in the front of the classroom. I am an assistant professor of chemistry at University of Richmond and

4h

Improving diversity in the physical sciences needs more than data — it needs resolve, too

Improving diversity in the physical sciences needs more than data — it needs resolve, too Improving diversity in the physical sciences needs more than data — it needs resolve, too, Published online: 07 May 2019; doi:10.1038/d41586-019-01418-w Efforts to measure the scale of the problem are important, but so is acting on them.

4h

The CIA Sets Up Shop on Tor, the Anonymous Internet

Even the Central Intelligence Agency has a so-called onion service now.

4h

Leonardo da Vinci's early work on friction founded the modern science of tribology

For most people, the first thing that comes to mind when they think of Leonardo da Vinci is the Mona Lisa, or his sketches of the Vitruvian man. Fans of pulp fiction or popular cinema might even find their minds drifting to memories of The Da Vinci Code, the mystery thriller. Not me, though. I'm engaged in the study of friction, the force resisting the relative motion between surfaces. What most p

4h

Physicists-turned-sleuths hunt for WWII German uranium

The legacy of the Nazis’ last ditch experiments continues to beguile and baffle. Nick Carne reports.

4h

Wrinkles in the fabric of spacetime

New analysis suggests gravitational waves leave lasting marks on the particles they strike. Alan Duffy reports.

4h

Scientists confirm ancient Chinese astronomical observations

Galaxy cluster nebula one of the earliest things recorded outside the solar system. Andrew Masterson reports.

4h

Grunt work: the psychological effect of loud tennis

Researchers find grunting tennis players lead opponents to over-estimate their strength. Andrew Masterson reports.

4h

Chickpea genome clues to more robust crops

Multinational research reveals pathways to boosting the world’s second largest legume crop. Biplab Das reports.

4h

Valget er udskrevet: Her er lægernes ønsker til politikerne

Sundhedsområdet er vigtigt, politikerne skal holde, hvad de lover og forholde sig til fakta. Sådan lyder ønskerne fra tre læger til den kommende valgkamp.

4h

Health professionals wary of medicinal cannabis misuse and adverse effects

An analysis by Queensland University of Technology (QUT) of published studies gauging attitudes to medicinal cannabis has found that while health professionals are broadly supportive, they feel they lack clinical and legislative knowledge, and their greatest concerns are the psychiatric harm that may be caused to patients and misuse by recreational drug users.

4h

Mystery of texture of Guinness beer: inclination angle of a pint glass is key to solution

A team of researchers from Osaka University and Kirin Holdings Company, Limited demonstrated that the texture-formation in a pint glass of Guinness beer is induced by flow of a bubble-free fluid film flowing down along the wall of the glass, a world first. This phenomenon is found to be analogous to roll waves commonly observed in water sliding downhill on a rainy day. Their research results were

4h

Vaccine for African swine fever may save our bacon

Wild boar can be immunized against African Swine Fever by a new vaccine delivered to the animals in their food. This is the first report of a promising inoculation against this deadly disease, which is a worldwide threat to the swine industry. The study shows immunity can be passed on via contact, but further studies need to examine how this occurs, the safety of repeated administration and its ge

4h

Early hurricanes cause more mosquito-borne disease

The timing of a hurricane is one of the primary factors affecting the spread of mosquito-borne infectious diseases such as West Nile virus, dengue, chikungunya, and Zika, a new study shows. Researchers developed a mathematical model to study the impact of heavy rainfall events (HREs) such as hurricanes on the transmission of vector-borne infectious diseases in temperate areas of the world, includ

4h

How to remember everything you read

One of the ways you can deconstruct an argument is being actively attuned to what you're reading. To better remember content, take a blank sheet of paper and write down what you know about that subject. You can write it in bullet points. When you later come back to what you're reading, go to that sheet and skim it – it will prime your brain for what you're going to read. The Great Mental Models:

4h

A Small-Molecule CRISPR Inhibitor

The number of stories and journal articles about how CRISPR DNA-editing technology works, has worked, and is planned to work are beyond counting. How about an article about how to stop it in its tracks? That’s this one , just published in Cell from a multicenter team in Cambridge and New York. It describes a screening program for small-molecule inhibitors of S. pyogenes Cas9 (spCas9), because one

4h

This pyrotechnics expert turned his Minnesota backyard into a DIY fireworks testing ground

Science Ken Miller designs smoke displays for NFL games and air shows, but he tests his most destructive creations at home. Ken Miller designs smoke displays for NFL games and air shows, but he tests his most destructive creations at home.

4h

Lufthansa eyes Thomas Cook's Condor with buyout offer

European airline giant Lufthansa said Tuesday it had offered to buy carrier Condor from British parent company Thomas Cook, opening a new chapter in its fast-paced growth through buyouts.

4h

Farmers have Britain's most lethal job – here's how to make them safer

Britain's farmers are almost 18 times more likely to be killed on the job than the average industrial worker, and the fatality rate is increasing. Look through the government's summary of the 33 fatal farm, forestry and fishing accidents in 2017/18 and there were a number of types of fatalities such as falls, crushes, electrocutions and equipment malfunctions. Most people (but not farmers) might b

4h

Svært at få viden fra universiteter ud til virksomhederne

Væksthåbet Rehfeld Medical er et eksempel på, at teknisk viden på universiteterne baner vejen for ny vækst. Men det er en barsk proces.

4h

New material also reveals new quasiparticles

Researchers at PSI have investigated a novel crystalline material that exhibits electronic properties that have never been seen before. It is a crystal of aluminum and platinum atoms arranged in a special way. This resulted in novel properties of electronic behaviour for the crystal as a whole, including so-called Rarita-Schwinger fermions in its interior.

4h

Close relatives can coexist: two flower species show us how

Scientists have discovered how two closely-related species of Asiatic dayflower can coexist in the wild despite their competitive relationship. Through a combination of field surveys and artificial pollination experiments, the new study shows that while reproductive interference exists between the two species, both can counter the negative effects of this interference through self-fertilization.

4h

Cell architects: 'Smart cells' improve production of pharmaceutical raw materials

Researchers in Japan have developed an integrated synthetic biology system to construct new metabolic pathways and enzymes within microbes. By incorporating a "Design, Build, Test, Learn" (DBTL) workflow, the production of pharmaceutical raw materials could be systematically optimized. This application supports the concept of the DBTL workflow as a sustainable method for production of complex and

4h

New species of fish parasite named after Xena, the warrior princess

A study of crustacean parasites attaching themselves inside the branchial cavities (the gills) of their fish hosts was conducted in order to reveal potentially unrecognised diversity of the genus Elthusa in South Africa. While there had only been one known species from South Africa, a new article published in the open-access journal ZooKeys adds another three to the list, including one named after

4h

Porsche fined 535 mn euros over diesel cheating

German sports car maker and Volkswagen subsidiary Porsche will pay a 535-million-euro ($598 million) fine over diesel vehicles that emitted more harmful pollutants than allowed, Stuttgart prosecutors said Tuesday.

4h

Phytoplankton decline coincides with warming temperatures over the last 150 years

Virtually all marine life depends on the productivity of phytoplankton—microscopic organisms that work tirelessly at the ocean's surface to absorb the carbon dioxide that gets dissolved into the upper ocean from the atmosphere.

4h

Study shows long spaceflights lead to increase in brain ventricle size

A large team of researchers with members from Belgium, Russia, and Germany has found that people who spend a long time aboard the International Space Station experience an increase in the size of some of their brain ventricles. In their paper published in Proceedings of the National Academy of Sciences, the group describes their study of brain ventricles in cosmonauts that spent a significant amou

4h

Adding satnav to turn power grids into smart systems

An ESA-backed project is harnessing satnav to insert an intelligent sense of place and time to power grids, to provide early warning of potentially dangerous electricity network failures.

4h

Why climate change won't spur a 2008-style global financial crisis

Amid the very legitimate dire warnings from scientists and others about the future worsening impacts of climate change, there is also, unfortunately, a great deal of hyperbole about how much worse things will get. Often it is difficult to separate truth from mere speculation.

5h

5h

A scientist's work to protect the pork industry from virus outbreaks

In 2015, an outbreak of bird flu destroyed more than 50 million chickens and turkeys in the United States. Within a matter of months, affected states reeled from the overwhelming damage: in Iowa alone, economic losses were estimated at $1.2 billion, and thousands of jobs were lost.

5h

Study explores genetics behind evolution of flightless birds

Since Darwin's era, scientists have wondered how flightless birds like emus, ostriches, kiwis, cassowaries, and others are related, and for decades the assumption was that they must all share a common ancestor who abandoned the skies for a more grounded life.

5h

U.S. Pressure Blocks Declaration on Climate Change at Arctic Talks

The disagreement left the Arctic Council, which was formed to help protect the region's fragile environment, unable to issue a joint declaration for the first time in its history.

5h

A scientist's work to protect the pork industry from virus outbreaks

In 2015, an outbreak of bird flu destroyed more than 50 million chickens and turkeys in the United States. Within a matter of months, affected states reeled from the overwhelming damage: in Iowa alone, economic losses were estimated at $1.2 billion, and thousands of jobs were lost.

5h

Study explores genetics behind evolution of flightless birds

Since Darwin's era, scientists have wondered how flightless birds like emus, ostriches, kiwis, cassowaries, and others are related, and for decades the assumption was that they must all share a common ancestor who abandoned the skies for a more grounded life.

5h

Photodoping in 2-D materials for fabrication of logic devices

National University of Singapore scientists have discovered a method for photoinduced electron doping on molybdenum ditelluride (MoTe2) heterostructures for fabricating next generation logic devices.

5h

KAIST identifies the cause of sepsis-induced lung injury

A KAIST research team succeeded in visualizing pulmonary microcirculation and circulating cells in vivo with a custom-built 3D intravital lung microscopic imaging system. They found a type of leukocyte called neutrophils aggregate inside the capillaries during sepsis-induced acute lung injury (ALI), leading to disturbances and dead space in blood microcirculation. According to the researchers, thi

5h

The evolution of skyrmions in multilayers and their topological Hall signature

The topological Hall effect (THE) is the Hall response to an emergent magnetic field, a manifestation of the skyrmion Berry-phase. As the magnitude of THE in magnetic multilayers is an open question, it is imperative to develop comprehensive understanding of skyrmions and other chiral textures, and their electrical fingerprint.

5h

Tumor mutations may predict response to immunotherapy

Center say they have found a potential explanation for the failures.

5h

Climate change — early spring: Predicting budburst with genetics

Tree and shrub genetics can be used to produce more accurate predictions of when leaves will burst bud in the spring, according to a Canada-US study.

5h

PolyU develops palm-sized 3D ultrasound imaging system for scoliosis mass screening

The first-of-its-kind palm-sized 3D ultrasound imaging system for radiation-free scoliosis assessment, named 'Scolioscan Air', can bring accurate, safe and cost-efficient mass screening to schools and anywhere in the community.

5h

Bacterial toxin research could improve pesticides and help treat cancer

Research into an intricate toxin delivery system found in bacteria could overcome the problem of pesticide resistance in insects, and might even lead to new cancer treatments.

5h

Fewer cars a sensible plan for a liveable future

More shared spaces, safer streets and fewer cars in the city are all part of a newly released ten-year plan by the City of Melbourne. This evening, Town Hall will consider the ambitious draft transport strategy that would boost pedestrian, cycling and tram access across the CBD's Hoddle Grid.

5h

The uranium mine in the heart of Kakadu needs a better cleanup plan

Can a uranium mine be rehabilitated to the environmental standards of a national park and World Heritage site?

5h

Bacterial toxin research could improve pesticides and help treat cancer

Research into an intricate toxin delivery system found in bacteria could overcome the problem of pesticide resistance in insects, and might even lead to new cancer treatments.

5h

New desalination method could get industry – and the environment – out of a very salty pickle

"Hypersaline brine" is industrial waste-water with salt levels that exceed even that of seawater. It's a big, expensive, destructive problem which a team of engineers at Columbia University …

5h

From the archive

From the archive From the archive, Published online: 07 May 2019; doi:10.1038/d41586-019-01425-x How Nature reported an explanation for biological clocks in 1969, and a nature reserve in Tasmania in 1919.

5h

Do this if you need to make decisions better and faster

For some people, decision-making comes easily. When faced with multiple options, these lucky few quickly and confidently pick the one that they think would work best. But for the rest of us, making decisions can be a challenge — especially if you have a time limit and it's a major life decision. Believe it or not, it's entirely possible to get better — and faster — at making decisions. Dean Grazi

5h

Folketinget nåede det lige inden valg: Vedtog kritiserede miljøzoner

En mild stramning af loven om miljøzoner var et af kun to forslag, som Lars Løkke Rasmussen afventede vedtagelsen af, inden han udskrev folketingsvalg.

5h

Can "the Pill" Improve Relationship Satisfaction?

Taking birth control pills might have broad, unintended, and even surprising side-effects — Read more on ScientificAmerican.com

5h

Cannibalism was profitable for Homo antecessor

Jesús Rodríguez, Ana Mateos and Guillermo Zorrilla, scientists at the Centro Nacional de Investigación sobre la Evolución Humana (CENIEH), have just published a study in the Journal of Human Evolution in which they analyze the cannibalistic behavior of populations at Atapuerca 1 million years ago. The results make it clear that anthropophagy was a profitable strategy for Homo antecessor.

5h

Nanoparticles can aid in stroke therapy

Tiny selenium particles could have a therapeutic effect on ischemic brain strokes by promoting the recovery of brain damage. Pharmacologists, including Alireza Mashaghi from the Leiden Academic Centre for Drug Research discovered that selenium nanoparticles inhibit molecular mechanisms that are responsible for the loss of brain cells after a stroke. The results were published in Nature Scientific

5h

When biodegradable plastic is not biodegradable

The idea of a "biodegradable" plastic suggests a material that would degrade to little or nothing over a period of time, posing less of a hazard to wildlife and the environment. This is the sort of claim often made by plastic manufacturers, yet recent research has revealed supposedly biodegradable plastic bags still intact after three years spent either at sea or buried underground. So un-degraded

5h

The fossilization process of dinosaur remains

A study conducted between the UPV/EHU-University of the Basque Country and the University of Zaragoza has conducted an in-depth analysis of the dinosaur fossils at La Cantalera-1, one of the Iberian sites belonging to the Lower Cretaceous with the largest number of vertebrates. The structure of the fossilized bone tissue as well as the fossilization processes have been studied. It has been possibl

5h

Hunting jeopardizes forest carbon storage, yet is overlooked in climate mitigation efforts

The loss of animals, often due to unregulated or illegal hunting, has consequences for the carbon storage capacity of forests, yet this link is rarely mentioned in high-level climate policy discussions, according to a new study from Lund University in Sweden and the University of Copenhagen in Denmark.

5h

Calculate the G’s of Using an Ejection Seat to Blast Out of a Jet

Using a jet's ejection seat to escape in an emergency means weathering some "hurt" level acceleration, as this video shows.

5h

The Law Being Used to Prosecute Julian Assange Is Broken

Opinion: Julian Assange is being prosecuted under the Computer Fraud and Abuse Act, a minimally defined statute that can have maximally destructive consequences.

5h

How the Videogame Aesthetic Flows Into All of Culture

Videogames show us how digital media in general, from YouTube to Twitter, lend themselves easily to the selfsame aesthetics of flow.

5h

New York City Has Been Obliterated in a New Asteroid-Impact Simulation

Fake New York City exploded in a fake asteroid impact that was just a simulation, but the danger is very real.

5h

Apalutamide in prostate cancer: indication of considerable added benefit

Symptomatic progression is significantly retarded by this drug. This advantage clearly outweighs the disadvantages presented by some side effects.

5h

Genome editing helps decipher a congenital liver disease

Congenital hepatic fibrosis (CHF) is a rare genetic disease that can lead to severe liver impairment. The symptoms of CHF are distinct compared to other liver ailments, and while the PKHD1 gene has been implicated, the exact molecular basis for the unique disease pathology is unknown. Using a CRISPR-generated model, researchers at Tokyo Medical and Dental University (TMDU) identified molecular tar

5h

Obesity reprograms immune cells in breasts to promote tumor formation

Macrophages in adipose tissue (fat) link obesity to triple-negative breast cancer. Instead of fighting breast cancer, these immune cells actually promote it.

5h

Politikere: Vi skal holde fast i life science som motor for dansk industri

Politikere fra DF, LA og SF var enige om at bakke op om life science sektoren, da medicinalfirmaet Roche tirsdag holdt paneldebat, inden statsministeren udskrev valg, om sundhedsvæsenets og life science branchens udfordringer. Der var dog et andet spørgsmål som skabte uenighed.

5h

Can "the Pill" Improve Relationship Satisfaction?

Taking birth control pills might have broad, unintended, and even surprising side-effects — Read more on ScientificAmerican.com

5h

Naturally heat-resilient corals transplanted to nurseries survive El Nino bleaching event

A pair of researchers with Stanford University has found that some naturally heat-resistant corals were able to survive relocation, even after an El Nino warming event. In their paper published in Proceedings of the National Academy of Sciences, Megan Morikawa and Stephen Palumbi describe their study of ways to prevent the coral loss and what they found.

5h

Teenagers might not report online abuse because they often don't see it as a problem

Protecting children from harm online is high on the political agenda right now. The UK government has set out plans to make social media companies legally responsible for protecting users, and MPs have criticised social media platforms for relying on users to report abuse.

5h

Tinder-style approach could help organisations' partnerships and projects to flourish

The fear of being rejected and losing face can have such a big impact that companies and policy-makers could consider introducing `Tinder-style' matching environments, according to new research from the University of Exeter Business School.

5h

Study finds gap between rich and poor growing regionally, too

There's an old saying about a rising tide lifting all boats—and for more than a century, as the gap between the richest and poorest parts of the U.S. shrank, it seemed as though, in America at least, it might be true.

5h

Hotade skalbaggar gynnas av skogsgallring

När traditionellt skogsbruk övergick i modernt under 1900-talet, blev många av de syd- och mellansvenska skogarna tätare och mörkare än de tidigare varit. För många arter i solbelysta och öppna skogar, och som har eken som sitt livsutrymme, har det inneburit en ökad risk för utdöende. – De här insekterna utgör en stor del av den biologiska mångfald som vi i lag och med internationella överenskomm

5h

5h

5h

5h

5h

Why Amazon Is Gobbling Up Failed Malls

submitted by /u/gone_his_own_way [link] [comments]

5h

MEPs lead calls for better oversight of AI, robots

submitted by /u/gone_his_own_way [link] [comments]

5h

Pesticide research must stay transparent and independent

Few people would make an important purchase on trust alone. The same logic applies to pesticides.

5h

Study examines benefits of teaching math in culturally responsive ways

Teachers have long known that to reach learners, developing instruction that relates to those students' experiences can be a valuable tool. That is as true for mathematics as other subjects, yet there had not been a comprehensive review of the research on teaching mathematics to culturally and linguistically diverse learners in culturally responsive ways. Two University of Kansas researchers have

5h

Small tyrannosaur 'was cousin of T. rex'

A 92-million-year-old dinosaur provides evolutionary insights on the evolution of the tyrannosaurs.

5h

Pesticide research must stay transparent and independent

Few people would make an important purchase on trust alone. The same logic applies to pesticides.

5h

New discovery could alleviate salty soil symptoms in food crops

New research published in Nature Scientific Reports (opens in new window) has found that a hormone produced by plants under stress can be applied to crops to alleviate the damage caused by salty soils. The team of researchers from Western Sydney University and the University of Queensland identified a naturally-occurring chemical in plants that reduces the symptoms of salt stress in plants when ap

5h

Exploring the effects of moisture and drying on cement

Although it is used to construct some of the world's largest structures, it turns out that cement actually has something in common with a sponge.

5h

Lead contamination found in baby teeth of children living near Exide battery plant

Airborne lead from recycled car batteries at the Exide plant in Vernon ended up in the baby teeth of children living nearby, a USC study shows.

5h

New discovery could alleviate salty soil symptoms in food crops

New research published in Nature Scientific Reports (opens in new window) has found that a hormone produced by plants under stress can be applied to crops to alleviate the damage caused by salty soils. The team of researchers from Western Sydney University and the University of Queensland identified a naturally-occurring chemical in plants that reduces the symptoms of salt stress in plants when ap

5h

Self-healing cement could transform geothermal industry

A self-healing cement developed by Pacific Northwest National Laboratory can outperform conventional concrete, offering a potentially pollution-preventing technology for the growing geothermal industry.

5h

Highly qualified staff at state preschools overcome private sector staffing advantage

Staff who are better qualified and trained maintain the quality of state-funded preschools, to some extent making up for the larger number of children per staff member in comparison to private and voluntary settings. A comparison of data before and after substantial UK policy change between 1999 and 2014, aimed at increasing uptake and improving the quality of early years education and care, sugge

5h

Two flower species show that close relatives can coexist

Scientists have discovered how two closely-related species of Asiatic dayflower can coexist in the wild despite their competitive relationship. Through a combination of field surveys and artificial pollination experiments, the new study shows that while reproductive interference exists between the two species,Commelina communis and Commelina communis forma ciliata, both can counter the negative ef

6h

Q&A: To Crickets, Your Basement Is a Cafeteria

It’s dark, it’s damp, and there’s lots more to eat down there than you’d think.

6h

Ocean activity is key controller of summer monsoons

Each summer, a climatic shift brings persistent wind and rain to much of Southeast Asia, in the form of a seasonal monsoon. The general cause of the monsoon is understood to be an increasing temperature difference between the warming land and the comparatively cool ocean. But for the most part, the strength and timing of the monsoon, on which millions of farmers depend each year, is incredibly dif

6h

Effective incentives help people overcome procrastination

Researchers from Harvard, Yale and BYU have found a useful tool in overcoming procrastination when it comes to making financial decisions.

6h

Two flower species show that close relatives can coexist

Scientists have discovered how two closely-related species of Asiatic dayflower can coexist in the wild despite their competitive relationship. Through a combination of field surveys and artificial pollination experiments, the new study shows that while reproductive interference exists between the two species,Commelina communis and Commelina communis forma ciliata, both can counter the negative ef

6h

Precise temperature measurements with invisible light

Ordinarily, you won't encounter a radiation thermometer until somebody puts one in your ear at the doctor's office or you point one at your forehead when you're feeling feverish. But more sophisticated and highly calibrated, research-grade "non-contact" thermometers – which measure the infrared (heat) radiation given off by objects without touching them – are critically important to many endeavors

6h

Ensuring oral medicines are protected from the acidic conditions of the stomach

A group of chemical and biomedical engineers at UNSW Sydney and University of Cambridge has improved the chemical stability of 'ZIF crystals', enabling these porous nanomaterials to be used for smart pharmaceutical drug delivery in the human body.

6h

Predicting early spring budburst with genetics against a climate change backdrop

Although climate skeptics might find it hard to believe with this year's endless snow and freezing temperatures, climate change is making warm, sunny early springs increasingly common. And that affects when trees start to leaf out. But how much? In a study published in Methods in Ecology and Evolution, Simon Joly, biology professor at Université de Montréal and Elizabeth Wolkovich, an ecology prof

6h

Scientists identify bioactive compounds in cacao pods to develop drugs to combat skeletal disorders

An international team of researchers, led by the University of Granada (UGR) in Spain, has successfully isolated a bioactive compound present in cocoa bean extract that has proven effective in combating skeletal diseases such as achondroplasia. This genetic bone dysplasia, the primary cause of dwarfism, is a rare disease that affects one in 25,000 newborns. To date, no effective treatment has been

6h

El Nino has rapidly become stronger and stranger, according to coral records

The pattern of El Niño has changed dramatically in recent years, according to the first seasonal record distinguishing different types of El Niño events over the last 400 years.

6h

Freshwater mussel shells were material of choice for prehistoric craftsmen

A new study suggests that 6000-years-ago people across Europe shared a cultural tradition of using freshwater mussel shells to craft ornaments.

6h

Synthetic and living micropropellers support convection-enhanced nanoparticle transport

Nanoparticles (NPs) are a promising platform for drug delivery to treat a variety of diseases including cancer, cardiovascular disease and inflammation. Yet the efficiency of NP transfer to the diseased tissue of interest is limited due to an assortment of physiological barriers. One significant hurdle is the transport of NPs to precisely reach the target tissue of interest. In a recent study, S.

6h

New open source software eases the pain of multiple UI designs

The time-consuming and labor-intensive task of designing multiple user interfaces for different screen sizes and orientations could become a thing of the past thanks to open-source software that uses a new paradigm to speed up or even automate the process.

6h

Maternal nut consumption during pregnancy linked to improvements in neurodevelopment in children

For the first time links have been observed between a nut-rich maternal diet during the first trimester of pregnancy and better outcomes after birth in cognitive function, attention capacity and long-term working memory.

6h

The fascinating and terrifying worlds beneath our feet

The fascinating and terrifying worlds beneath our feet The fascinating and terrifying worlds beneath our feet, Published online: 07 May 2019; doi:10.1038/d41586-019-01421-1 Huw Lewis-Jones relishes a scientific and poetic journey underground.

6h

Bypassing popular passwords

Every year computer security companies share their findings regarding passwords and data breaches. Again and again, they warn computer users to use complex passwords and not to use the same passwords for different accounts. And, yet, data breaches and other sources show that too many people use the same simple passwords repeatedly and that some of those passwords are ludicrously simple, the word "

6h

Freshwater mussel shells were material of choice for prehistoric craftsmen

An international team of researchers, including academics from the University of York, have discovered that 6000-years-ago people across Europe shared a cultural tradition of using freshwater mussel shells to craft ornaments.

6h

Microsoft Word AI 'to improve writing'

A new tool in Word promises to make writing clearer and more concise.

6h

Telescopes in space for even sharper images of black holes

Astronomers have just managed to take the first image of a black hole, and now the next challenge facing them is how to take even sharper images, so that Einstein's Theory of General Relativity can be tested. Radboud University astronomers, along with the European Space Agency (ESA) and others, are putting forward a concept for achieving this by launching radio telescopes into space. They publish

6h

Why Prior Probability Matters

Back in the early days of my skeptical career I attended a skeptical conference hosted by CSI (then CSICOP). One panel stuck out, and I still remember some details more than two decades later. This was a panel on extrasensory perception (ESP). The proponent on the panel argued that the research showing that ESP is real shows as much of an effect as the research showing that aspirin prevents strok

6h

How stereotypes sap power from female presidents

Female presidents have less power to shape policy and face higher standards in key policy areas than male presidents, according to a new study . “On average, female leaders come into office with less support than male leaders and their support erodes more quickly,” says lead author Ryan E. Carlin, an associate professor of political science at Georgia State University. “Furthermore, the public st

6h

No one-size-fits-all solution for sustainable agriculture

Sustainable agriculture production through the use of conservation farming is far from a global one-size-fits-all solution, according to new research from the University of Arizona.

6h

The most stable microscope in the world

Ph.D. candidate Irene Battisti of the Leiden Institute of Physics has developed the most vibration-free cryogenic scanning tunneling microscope in the world. The new microscope could shed light on unconventional superconductivity.

6h

Adam Savage's definitive guide to every kind of glue

DIY Excerpt: Every Tool's a Hammer Adam Savage's new book, "Every Tool's a Hammer," is on sale now.

6h

Master & Dynamic MW65 Active Noise-Canceling Wireless Over-Ear Headphones Review: Worth Every Penny

Takes the excellent sound M&D is known for and adds active noise-canceling.

6h

The Green New Deal is going global

It's the third period of Game 7 of the Stanley Cup playoffs and we're trailing, badly. It's time to pull the goalie and send out the top forward line. We don't know if we can actually win, but we're going to give it everything we've got.

6h

Microbes in the Pacific Ocean survive on arsenic

Arsenic is a deadly poison for most living things, but new research shows that microorganisms are breathing arsenic in a large area of the Pacific Ocean. Researchers have discovered that an ancient survival strategy is still being used in low-oxygen parts of the marine environment. “Thinking of arsenic as not just a bad guy, but also as beneficial, has reshaped the way that I view the element,” s

6h

Banning offshore oil and gas drilling

Last week, New York's Governor Andrew Cuomo signed a bill passed in February that banned oil and gas drilling off New York's coastline. The state's action was in part a response to the Trump Administration's plan to encourage drilling any place and in any way they can. New York's bill back in February was one of the first responses to the administration's newest proposal to promote fossil fuel ext

6h

Opinion: Forests instead of cathedrals

Notre Dame should not be rebuilt, argue Guillaume Habert and Alice Hertzog. In times of climate change and in light of the current religious landscape its reconstruction is no longer a priority.

6h

IHMC Atlas Autonomous Path Planning Across Narrow Terrain

submitted by /u/gone_his_own_way [link] [comments]

7h

7h

7h

Word’s new AI editor will improve your writing – TechCrunch

submitted by /u/gone_his_own_way [link] [comments]

7h

A small YouTube design change could drastically cut its CO2 emissions

A simple tweak to YouTube could reduce its annual carbon footprint by an amount equivalent to the footprint of 30,000 UK homes

7h

Maternal nut consumption during pregnancy linked to improvements in neurodevelopment in children

For the first time links have been observed between a nut-rich maternal diet during the first trimester of pregnancy and better outcomes after birth in cognitive function, attention capacity and long-term working memory.

7h

New class of catalysts for energy conversion

Many chemical reactions relevant for new energy sources are highly complex and result in considerable energy loss. Thus, energy conversion and storage systems or fuel cells are not yet widely used in commercial applications. Researchers at Ruhr-Universität Bochum (RUB) and Max-Planck-Institut für Eisenforschung in Düsseldorf are now reporting on a new class of catalysts that is theoretically suita

7h

Twisting whirlpools of electrons

In Jules Verne's famous classic 20,000 Leagues Under the Sea, the iconic submarine Nautilus disappears into the Moskenstraumen, a massive whirlpool off the coast of Norway. In space, stars spiral around black holes; on Earth, swirling cyclones, tornadoes and dust devils rip across the land.

7h

AMD and Cray are building the first exascale supercomputer with speeds in excess of 1.5 exaFLOPS

The exact specs for Frontier haven't been released yet, but it will be built using AMD EPYC CPUs, Radeon Instinct GPUs, and Cray Slingshot interconnects. Each node in the system will have one …

7h

Why Mathematicians Are Obsessed with (and Hoarding) This Chalk

It's considered the Rolls-Royce of chalk. Here's why.

7h

What It Was Like Making the Biggest Movie of 2019

The Marvel Cinematic Universe is defined by its spandex-clad stars—heroes including Captain America and Iron Man who’ve powered the franchise to unprecedented popularity over 11 years, most recently resulting in the record-breaking success of Avengers: Endgame . The interconnected nature of the 22 Marvel movies means a single film like Endgame , which brings the entire ensemble together for a big

7h

"Frost Fairs," the Little Ice Age and Climate Change

When the Thames would occasionally freeze in the 17th to the early 19th century, Londoners made the most of it — Read more on ScientificAmerican.com

7h

A belly full of wriggling worms makes wood beetles better recyclers

Common beetles that eat rotten logs chew up more wood when filled with a roundworm larvae, releasing nutrients more quickly back to the forest floor.

7h

Why Is Facebook Abetting Trump’s Reckless Foreign Policy?

Facebook and other big tech platforms seem ready to do the Trump administration’s bidding when it comes to how foreign governments use social media.

7h

How to Teach Kids to Be Independent Thinkers

Esther Wojcicki (mom of Susan, Janet, and Anne) on how to foster creativity in kids.

7h

"Frost Fairs," the Little Ice Age and Climate Change

When the Thames would occasionally freeze in the 17th to the early 19th century, Londoners made the most of it — Read more on ScientificAmerican.com

7h

7h

North Korea's Short-Range Missile Test Spotted from Space

Saturday's test was the first in 18 months by North Korea.

7h

Driving chemical reactions with light

The chemistry of photosynthesis is still poorly understood. However, researchers from Johannes Gutenberg University Mainz (JGU) in Germany and Rice University in Houston have now uncovered a major piece of the puzzle. Their findings have been published recently in Science Advances.

7h

Rice husks can remove microcystin toxins from water

Scientists at the University of Toledo have discovered that rice husks can effectively remove microcystin from water, a finding that could have far-reaching implications for communities along the Great Lakes and across the developing world.

7h

Quantum computing with graphene plasmons

A novel material that consists of a single sheet of carbon atoms could lead to new designs for optical quantum computers. Physicists from the University of Vienna and the Institute of Photonic Sciences in Barcelona have shown that tailored graphene structures enable single photons to interact with each other. The proposed new architecture for quantum computer is published in the recent issue of np

7h

Can Robots Help Pick Up after the Recycling Crisis?

They will have to overcome the challenges of America’s convenient single-stream recycling system — Read more on ScientificAmerican.com

7h

Can Robots Help Pick Up after the Recycling Crisis?

They will have to overcome the challenges of America’s convenient single-stream recycling system — Read more on ScientificAmerican.com

7h

Do you feel artificial Intelligence is overhyped in medical field and why?

Is there any category of medical care that can actually benefit from Artificial Intelligence because with the current development in medical care and AI, it seems almost impossible to see a foreseeable action plan to make AI part of medical care submitted by /u/ObjectiveLobster23 [link] [comments]

8h

8h

Automation: Is Anything Immune?

I've been doing a lot of research into A.I for a university course I'm completing. In the course, I've come across the idea of "weak" A.I and "strong" A.I. The distinction is that weak AI can simulate a human mind, while a strong AI can actually have a human mind. Ignoring strong AI for now, a lot of people make arguments that some jobs can't/won't be automated because they rely on giving people

8h

8h

8h

För tidig födsel kan ge kronisk njursjukdom senare i livet

Det väl känt att prematurt födda barn, före vecka 37, riskerar ”seneffekter” som vuxna, det vill säga konsekvenser av sjukdom och behandling. Det kan handla om olika former av komplikationer, bland annat vad gäller hjärt- och lungfunktion. – Med tanke på att för tidig födelse är vanligt, är fynden viktiga eftersom detta är något som kan drabba många. Dessa individer behöver uppföljning och föreby

8h

Spørg Fagfolket: Hvorfor påvirker kold vind min cykelhastighed mere?

En læser synes, at vinden er en del mere generende om vinteren, når han skal ud på cyklen. Har luften større massefylde da, eller hvad? Det svarer DMI på.

8h

Gladsaxe vil give borgerne direkte adgang til egne data

Efter et pilotforsøg vil Gladsaxe undersøge muligheden for at give borgere direkte adgang til data om sager og ydelser med NemID.

8h

Authors’ remorse: Researchers retract paper so they can publish it in a journal with a higher impact factor

Some researchers evidently have never heard the term “no backsies.” The authors of a paper on spine surgery have retracted the article because, well, they were fickle. We’ll explain. The paper, “Limited post-operative dexamethasone use does not affect lumbar fusion: a single institutional experience,” was published last June in the Journal of Spine Surgery by … Continue reading Authors’ remorse: R

8h

What scientists should know about visa hurdles

What scientists should know about visa hurdles What scientists should know about visa hurdles, Published online: 07 May 2019; doi:10.1038/d41586-019-01428-8 Be prepared for delays to start dates, unexpected fees — and even visa refusals — when moving abroad for career opportunities.

8h

Reboot ethics governance in China

Reboot ethics governance in China Reboot ethics governance in China, Published online: 07 May 2019; doi:10.1038/d41586-019-01408-y The shocking announcement of genetically modified babies creates an opportunity to overhaul the nation’s science, argue Ruipeng Lei and colleagues.

8h

Medie: Instagram vil advare brugere om vaccine-misinformation

Det virker bedre at advare om misinformation fremfor at fjerne den, lyder det fra Instagram.

8h

Why Is Trump Hiding His Tax Returns?

President Donald Trump has defied a congressional subpoena and refused to deliver his tax returns as the law requires. The headlines say that the decision is Secretary of the Treasury Steven Mnuchin’s, but that, of course, is a fiction. Mnuchin’s statement insists that he acted on the advice of the Department of Justice. But the law and the precedents are clear: Congressional subpoenas must be co

8h

Don’t Let Students Run the University

When did college students get it into their head that they should be running the university? The distressing trend of students somehow thinking that they’re the teachers began in earnest in the 1960s, a time when at least some of the grievances of campus protesters—from racism and sexism to the possibility of being sent to die in Southeast Asia—made sense. A more noxious version of this trend, ho

8h

Don’t Be Grateful That Dad Does His Share

I’ve spent the past year interviewing married or cohabiting heterosexual mothers across the United States about the distribution of child-care labor in their home. Most of them did the lion’s share of the work and were angry with their partner. Yet many of them told me they were “grateful.” Over and over again, I heard women complain that they were doing more than their partner, only to then insi

8h

David Brooks’s Journey Toward Faith

When David Brooks started writing his column in The New York Times more than a decade and a half ago, he became an instant star. Today, he’s one of America’s most influential columnists, insightful and elegant, able to catalyze debates on topics simply by writing about them. Yet anyone who has regularly read Brooks over the years—or, in my case, who knows and admires him—can see that his outlook

8h

8h

Probiotics Could Help Frogs and Bats Fight Wildlife Epidemics

Studies of the human microbiome have revealed the potential benefits of probiotics in treating health disorders and boosting immune function. Now, disease ecologists are exploring their use in other organisms — such as bats, frogs, and coral — to improve species' resilience to wildlife epidemics.

8h

How fireflies inspired energy-efficient lights

Studying fireflies helped scientists increase light extraction in LEDs by more than 50%

8h

8h

US climate change refusal sinks Arctic declaration: delegates

Members of the Arctic Council meeting in Finland's far north on Tuesday failed to issue their traditional final declaration due to a US refusal to mention climate change, delegates said.

9h

Singapore oulaws 'revenge porn', 'cyber-flashing'

Singapore has outlawed "revenge porn" and "cyber-flashing"—sending unsolicited images of one's private parts —the latest country to clamp down on sexual offences committed online.

9h

9h

Possible Outcomes of the Climate Crisis

submitted by /u/TheRaimonds [link] [comments]

9h

Study: Universal basic income doesn’t work.

submitted by /u/pluto3cubed [link] [comments]

9h

Ny professor skal forske i lungesygdomme hos børn og unge

Overlæge Kim G. Nielsen fra Dansk BørneLungeCenter på Rigshospitalet er udnævnt til professor i pædiatri og pædiatrisk pulmonologi.

9h

Optical backaction-evading measurement of a mechanical oscillator

Optical backaction-evading measurement of a mechanical oscillator Optical backaction-evading measurement of a mechanical oscillator, Published online: 07 May 2019; doi:10.1038/s41467-019-10024-3 Measurements of motion that avoid quantum backaction, with the potential to surpass the standard quantum limit, have so far been demonstrated using microwave radiation. Here, Shomroni, Qiu et al. demonstr

9h

Engineering atomic-level complexity in high-entropy and complex concentrated alloys

Engineering atomic-level complexity in high-entropy and complex concentrated alloys Engineering atomic-level complexity in high-entropy and complex concentrated alloys, Published online: 07 May 2019; doi:10.1038/s41467-019-10012-7 Designing complex concentrated alloys with targeted properties for high performance remains challenging because of their complex local atomic environments. Here, the au

9h

Twisted magnon beams carrying orbital angular momentum

Twisted magnon beams carrying orbital angular momentum Twisted magnon beams carrying orbital angular momentum, Published online: 07 May 2019; doi:10.1038/s41467-019-10008-3 The magnonic currents promise the opportunity for the energy efficient information processing and communication technologies. Here the authors theoretically show the propagating spin waves that carry orbital angular momentum c

9h

Resonance-enhanced three-photon luminesce via lead halide perovskite metasurfaces for optical encoding

Resonance-enhanced three-photon luminesce via lead halide perovskite metasurfaces for optical encoding Resonance-enhanced three-photon luminesce via lead halide perovskite metasurfaces for optical encoding, Published online: 07 May 2019; doi:10.1038/s41467-019-10090-7 Lead halide perovskites attract high interest as semiconductor materials but their exceptional nonlinear properties have not been

9h

Tuning the charge flow between Marcus regimes in an organic thin-film device

Tuning the charge flow between Marcus regimes in an organic thin-film device Tuning the charge flow between Marcus regimes in an organic thin-film device, Published online: 07 May 2019; doi:10.1038/s41467-019-10114-2 To demonstrate charge transfer in different Marcus regimes in an organic semiconductor, precise tuning of the material’s electronic properties is required. Here, the authors use a th

9h

Switching the activity of Cas12a using guide RNA strand displacement circuits

Switching the activity of Cas12a using guide RNA strand displacement circuits Switching the activity of Cas12a using guide RNA strand displacement circuits, Published online: 07 May 2019; doi:10.1038/s41467-019-09953-w Cas12a is a useful alternative to Cas9 for genome editing and regulation. Here the authors design strand displacement gRNAs that can add functionality to Cas12a by acting as multi-

9h

Caspase-1 initiates apoptosis in the absence of gasdermin D

Caspase-1 initiates apoptosis in the absence of gasdermin D Caspase-1 initiates apoptosis in the absence of gasdermin D, Published online: 07 May 2019; doi:10.1038/s41467-019-09753-2 In inflammasomes, caspase-1 activation leads to pyroptosis mediated by gasdermin D, but cells lacking gasdermin-D still initiate caspase-dependent cell death. Here, Tsuchiya et al. show that these cells undergo Bid-

9h

Capturing single-cell heterogeneity via data fusion improves image-based profiling

Capturing single-cell heterogeneity via data fusion improves image-based profiling Capturing single-cell heterogeneity via data fusion improves image-based profiling, Published online: 07 May 2019; doi:10.1038/s41467-019-10154-8 A challenge with single-cell resolution methods is that cell heterogeneity should be captured while allowing for comparisons between populations. Here the authors fuse in

9h

Global health benefits of climate action offset costs

New research in Nature Communications finds that immediate, dramatic cuts in global emissions — aggressive enough to meet the Paris Climate Agreement — are economically sound if human health benefits are factored in.

9h

Arsenic in drinking water may change heart structure

Among young adults, drinking water contaminated with arsenic may lead to structural changes in the heart that raise their risk of heart disease.

9h

Reducing carbon emissions while improving health is economically attractive, study shows

A study debuting a new climate policy model developed by Princeton University researchers and others reports it is economically sound to quickly and dramatically cut greenhouse gas emissions given the immediate and significant human health benefits.

9h

Chinese spies may have fed stolen NSA tools to Wannacry creators

A group called Shadow Brokers leaked sets of hacking tools back in 2017 that led to massive security breaches around the world, including the infamous WannaCry ransomware attacks. While …

9h

Samsung Is Asking Customers If They Wish To Cancel Their Galaxy Fold Orders

Samsung was expected to launch their Galaxy Fold foldable smartphone, but due to reports of early review units running into durability issues, the company decided to delay the launch of the …

9h

Designing an antidote for world's most venomous jellyfish

While studying the venom of box jellyfish — one of the most deadly animals on earth — researchers in Australia stumbled across a possible antidote.

9h

How Computer-Assisted Telepathy Helps Humans Communicate

The next phase of human evolution seems headed toward merging biological bodies with machines, and in the first video of Future You, Elise Hu gets connected to a network and plays a game her thoughts. (Image credit: Nick Michael/NPR)

9h

Stats: abuse by researchers’ lust for certainty

Stats: abuse by researchers’ lust for certainty Stats: abuse by researchers’ lust for certainty, Published online: 07 May 2019; doi:10.1038/d41586-019-01453-7 Stats: abuse by researchers’ lust for certainty

9h

Stop harvesting olives at night — it kills millions of songbirds

Stop harvesting olives at night — it kills millions of songbirds Stop harvesting olives at night — it kills millions of songbirds, Published online: 07 May 2019; doi:10.1038/d41586-019-01456-4 Stop harvesting olives at night — it kills millions of songbirds

9h

Stats: multiple experiments test biomedical conclusions

Stats: multiple experiments test biomedical conclusions Stats: multiple experiments test biomedical conclusions, Published online: 07 May 2019; doi:10.1038/d41586-019-01454-6 Stats: multiple experiments test biomedical conclusions

9h

Stats: is this therapy useful?

Stats: is this therapy useful? Stats: is this therapy useful?, Published online: 07 May 2019; doi:10.1038/d41586-019-01452-8 Stats: is this therapy useful?

9h

The sounds of science: biochemistry and the cosmos inspire new music

The sounds of science: biochemistry and the cosmos inspire new music The sounds of science: biochemistry and the cosmos inspire new music, Published online: 07 May 2019; doi:10.1038/d41586-019-01422-0 Elie Dolgin profiles a compelling collaboration between scientists and composers in Paris.

9h

Internationalize hazard management of China’s chemical plants

Internationalize hazard management of China’s chemical plants Internationalize hazard management of China’s chemical plants, Published online: 07 May 2019; doi:10.1038/d41586-019-01455-5 Internationalize hazard management of China’s chemical plants

9h

Serum amino acid profiles and risk of type 2 diabetes among Japanese adults in the Hitachi Health Study

Serum amino acid profiles and risk of type 2 diabetes among Japanese adults in the Hitachi Health Study Serum amino acid profiles and risk of type 2 diabetes among Japanese adults in the Hitachi Health Study, Published online: 07 May 2019; doi:10.1038/s41598-019-43431-z Serum amino acid profiles and risk of type 2 diabetes among Japanese adults in the Hitachi Health Study

9h

Changes in Pectoral Muscle Volume During Subacute Period after Radiation Therapy for Breast Cancer: A Retrospective up to 4-year Follow-up Study

Changes in Pectoral Muscle Volume During Subacute Period after Radiation Therapy for Breast Cancer: A Retrospective up to 4-year Follow-up Study Changes in Pectoral Muscle Volume During Subacute Period after Radiation Therapy for Breast Cancer: A Retrospective up to 4-year Follow-up Study, Published online: 07 May 2019; doi:10.1038/s41598-019-43163-0 Changes in Pectoral Muscle Volume During Subac

9h

Phylogenetics and species delimitations of the operculated land snail Cyclophorus volvulus (Gastropoda: Cyclophoridae) reveal cryptic diversity and new species in Thailand

Phylogenetics and species delimitations of the operculated land snail Cyclophorus volvulus (Gastropoda: Cyclophoridae) reveal cryptic diversity and new species in Thailand Phylogenetics and species delimitations of the operculated land snail Cyclophorus volvulus (Gastropoda: Cyclophoridae) reveal cryptic diversity and new species in Thailand, Published online: 07 May 2019; doi:10.1038/s41598-019-

9h

Overpressure at the Macondo Well and its impact on the Deepwater Horizon blowout

Overpressure at the Macondo Well and its impact on the Deepwater Horizon blowout Overpressure at the Macondo Well and its impact on the Deepwater Horizon blowout, Published online: 07 May 2019; doi:10.1038/s41598-019-42496-0 Overpressure at the Macondo Well and its impact on the Deepwater Horizon blowout

9h

Risk Factors for Ischemic Stroke in Atrial Fibrillation Patients Undergoing Radiofrequency Catheter Ablation

Risk Factors for Ischemic Stroke in Atrial Fibrillation Patients Undergoing Radiofrequency Catheter Ablation Risk Factors for Ischemic Stroke in Atrial Fibrillation Patients Undergoing Radiofrequency Catheter Ablation, Published online: 07 May 2019; doi:10.1038/s41598-019-43566-z Risk Factors for Ischemic Stroke in Atrial Fibrillation Patients Undergoing Radiofrequency Catheter Ablation

9h

GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study

GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study, Published online: 07 May 2019; doi:10.1038/s41598-019-43458-2 GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study

9h

Identification of a novel strong promoter from the anhydrobiotic midge, Polypedilum vanderplanki, with conserved function in various insect cell lines

Identification of a novel strong promoter from the anhydrobiotic midge, Polypedilum vanderplanki , with conserved function in various insect cell lines Identification of a novel strong promoter from the anhydrobiotic midge, Polypedilum vanderplanki , with conserved function in various insect cell lines, Published online: 07 May 2019; doi:10.1038/s41598-019-43441-x Identification of a novel strong

9h

Publisher Correction: 87Sr/86Sr age determination by rapidly formed spherical carbonate concretions

Publisher Correction: 87 Sr/ 86 Sr age determination by rapidly formed spherical carbonate concretions Publisher Correction: 87 Sr/ 86 Sr age determination by rapidly formed spherical carbonate concretions, Published online: 07 May 2019; doi:10.1038/s41598-019-40680-w Publisher Correction: 87 Sr/ 86 Sr age determination by rapidly formed spherical carbonate concretions

9h

Global health benefits of climate action offset costs

The price tag for cutting global emissions may seem expensive, until the human toll of deaths from air pollution and climate change are factored in, new research says.

9h

Image of the Day: New Tyrannosauroid

Fossils of two dinosaur skeletons found in New Mexico are from a species new to science that lived 92 million years ago.

9h

Crew Dragon-kapsel eksploderede: Ventil i redningssystem under mistanke

I april sprang SpaceX’ Crew Dragon-kapsel i luften. En bemandet tur bliver formentlig udskudt.

9h

Tag på tidsrejse gennem Danmarks natur: Naturlig natur er evig forandring

I lyset af FN's rapport om den hastige udryddelse af klodens biodiversitet tager Ingeniøren tilbage til istiden for at forstå, hvad oprindelig natur er – eller rettere ikke er.

9h

Scientists' hope of growing rare oat seeds 50 years on

Scientists are aiming to revive traditional varieties of oat which could stand up better to disease.

9h

5 glas alkohol i veckan ökar risken för blodpropp hos män

– Att stora mängder alkohol är en riskfaktor för blodpropp var känt, men nu kan vi se att risken börjar öka redan vid en alkoholkonsumtion som många nog betraktar som måttlig, säger Magdalena Johansson, doktorand vid Umeå universitet. Blodpropp, venös trombos, är en vanlig och allvarlig kärlsjukdom som kan leda till förtida död. De vanligaste formerna av venös trombos är blodproppar i benen och b

9h

Hoppande tarmbakterier

Många bakterier kan simma med hjälp av utskott som kallas flageller. Bakterierna skjuter fart med hjälp av flagellerna och tvärvänder när de stöter emot något. Rörelsemönstret kallas för ”run and tumble” och har framförallt observerats hos bakterier som rör sig i vatten eller andra lättflytande lösningar. Men exempelvis tarmbakterier måste ta sig fram genom en geléartad soppa. Forskare från Prince

9h

Dutch nutrition group DSM beats forecasts for first-quarter sales

Company raises full-year outlook thanks to ‘exceptional’ growth

9h

9h

9h

Homemade energy gets boost to go mainstream

New rules and initiatives to support communities wanting to produce their own renewable energy could help ordinary people play a key role in the European Union's transition to clean energy.

10h

Hemmeligholdt notat undergraver omstridt del af Femern-prognose

PLUS. Der var ikke dokumentation for, at Femernforbindelsen ville overflytte 718.000 personbiler fra Storebæltsbroen. Det rigtige tal er cirka 44 procent lavere.

10h

Tillgänglighet i bostaden är nyckeln till ett delaktigt liv för ryggmärgsskadade

Att kunna sköta sin hygien, laga en bit mat och råda sig själv i sitt hem är exempel på delaktighet. Men hur enkelt är det att vara delaktig hemma för den som är äldre och lever med ryggmärgsskada? I sin avhandling belyser arbetsterapeuten och forskaren Lizette Norin vikten av tillgänglighet i bostaden.

10h

Ancient Rock Art in the Plains of India

Two amateur sleuths have uncovered a collection of mysterious rock carvings on the Indian coastal plain south of Mumbai.

10h

11h

Man, the humans in this AI-created video look jaw-droppingly real

submitted by /u/trot-trot [link] [comments]

11h

Monster cartel charge puts brakes on BMW earnings

German high-end carmaker BMW on Tuesday reported a plunge in profits in the first quarter as it booked a 1.4-billion-euro ($1.6 billion) charge related to an EU cartel probe.

11h

Indonesia's Mt. Sinabung spews massive smoke-and-ash column

An Indonesian volcano erupted Tuesday, sending a massive column of ash and smoke 2,000 metres (6,500 feet) into the air, coating local villages in debris.

11h

Highly qualified staff at state preschools overcome private sector staffing advantage

Better-qualified staff maintain the quality of state-funded preschools, making up for the larger number of children per staff member in comparison to private and voluntary settings, finds a new study by researchers at the University of Oxford. They also show that the quality of private early years settings can be predicted by staff qualifications, and for voluntary settings, an in-house training p

11h

Developed countries benefit economically from counterterrorism efforts

A new study in Oxford Economic Papers suggests that developed counties may see significant economic gains from their efforts to combat terrorist threats. Developing counties, in contrast, appear to suffer economically from counterterrorism threats.

11h

British bluebells 'have advantage over Spanish bluebells'

There had been fears the plant could go extinct, after a Spanish variety escaped into the wild.

11h

Google I/O 2019 Liveblog: All the News as It Happens

Google's developer conference kicks off on May 7 at 10 am Pacific. Follow along with us for analysis and commentary from WIRED's editors.

11h

New open source software eases the pain of multiple UI designs

The time-consuming and labour-intensive task of designing multiple user interfaces for different screen sizes and orientations could become a thing of the past thanks to open-source software that uses a new paradigm to speed up or even automate the process.

11h

The Scientific Attitude, Not the Scientific Method, Is the Key

A philosopher of science argues that science is not characterized by a specific scientific method but by the scientific attitude. Scientists value empirical evidence and follow the evidence wherever it leads. They are open to changing their mind rather than stubbornly clinging to an ideological belief system.

11h

Merging cell datasets, panorama style

A new algorithm developed by MIT researchers takes cues from panoramic photography to merge massive, diverse cell datasets into a single source that can be used for medical and biological studies.

11h

Merging cell datasets, panorama style

A new algorithm developed by MIT researchers takes cues from panoramic photography to merge massive, diverse cell datasets into a single source that can be used for medical and biological studies.

11h

Here Are 6 Science-Backed Ways We Can Actually Tackle Climate Change

We have the tools to make our future better.

11h

Indigenous peoples, 'guardians of Nature', under siege

From Amazon rainforests to the Arctic Circle, indigenous peoples are leveraging ancestral knowhow to protect habitats that have sustained them for hundreds and even thousands of years, according to a landmark UN assessment of biodiversity released Monday.

11h

San Francisco to join list of those banning cashless stores

San Francisco is about to require brick-and-mortar retailers to take cash as payment, joining Philadelphia and New Jersey in banning a growing paperless practice that critics say discriminates …

11h

Google expected to show off new hardware, AI at annual event

Google CEO Sundar Pichai is expected to showcase much-anticipated updates to the company's hardware lines and artificial intelligence Tuesday during his keynote at the company's annual I/O conference for software developers.

11h

Amazon to open first Go store that accepts cash

Amazon launched its high-tech Go convenience store a year ago, where shoppers can pull items off the shelf and walk out.

11h

Modern sculpture meets ancient Greece in unique island exhibition

A stone's throw from the Greek island of Mykonos lies Delos, an uninhabited islet a world away from its neighbour's glamorous nightlife.

11h

Canada lists three whale species as threatened

Canadian scientists on Monday listed three types of whale that swim its waters, including two of the world's largest species, as threatened.

11h

Recent airline crashes run against trend toward safer flying

After a long trend toward greater safety in air travel, there has been an uptick in airline accidents and deaths in 2018 and 2019.

11h

Canada lists three whale species as threatened

Canadian scientists on Monday listed three types of whale that swim its waters, including two of the world's largest species, as threatened.

11h

Strong 7.2 quake rocks Papua New Guinea

A powerful but deep 7.2-magnitude earthquake rocked Papua New Guinea on Tuesday, officials said, cutting power and knocking items off shelves though there were no immediate reports of serious damage.

12h

San Francisco to join list of those banning cashless stores

San Francisco is about to require brick-and-mortar retailers to take cash as payment, joining Philadelphia and New Jersey in banning a growing paperless practice that critics say discriminates against low-income people who may not have access to credit cards.

12h

12h

The Strange Journey of an NSA Zero-Day—Into Multiple Enemies' Hands

How a "secret" hackable bug found by the NSA was used over by Chinese, North Korean, and Russian hackers to wreak havoc.

12h

12h

Public dread of nuclear power limits its use

submitted by /u/Bullet_Storm [link] [comments]

12h

New open source software eases the pain of multiple UI designs

The time-consuming and labor-intensive task of designing multiple user interfaces for different screen sizes and orientations could become a thing of the past thanks to open-source software that uses a new paradigm to speed up or even automate the process.

13h

The Far Right Wants to Gut the EU, Not Kill It

BERLIN—Ahead of this month’s European Parliament elections, the far-right populist Alternative for Germany (AfD) party has been advocating leaving the euro zone and even, potentially, the European Union entirely. A few years ago, the party membership’s decision to include a so-called Dexit in its 2019 platform—dependent, they say, on whether or not the EU accedes to its demands for significant re

13h

Collision-detecting suitcase, wayfinding app help blind people navigate airports

Carnegie Mellon University researchers say a smart suitcase that warns blind users of impending collisions and a wayfinding smartphone app can help people with visual disabilities navigate airport terminals safely and independently.

14h

Side-by-side comparison on point of care tests for blood's ability to clot

During big procedures like open heart surgery, patients need anticoagulants to prevent dangerous blood clot formation and regular bedside monitoring to make sure the drugs aren't also causing problems like excessive bleeding.

14h

Developed countries benefit economically from counterterrorism efforts

A new study in Oxford Economic Papers suggests that developed counties may see significant economic gains from their efforts to combat terrorist threats. Developing counties, in contrast, appear to suffer economically from counterterrorism threats.

14h

A moody gut often accompanies depression — new study helps explain why

A new study suggests that depression and GI trouble sometimes spring from the same source — low serotonin — and identifies a potential treatment that could ease both conditions simultaneously.

14h

Study shows adult tourniquet suitable for school-age children

Researchers with Nemours Children's Health System have shown the effectiveness of an adult tourniquet for use in children, according to a study published by the journal Pediatrics. While developed for adults, the military's Combat Application Tourniquet (CAT) is effective in controlling blood flow in children's arms and legs, as measured by Doppler pulse. This is the first, prospective study on th

14h

Highly qualified staff at state preschools overcome private sector staffing advantage

Staff who are better qualified and trained maintain the quality of state-funded preschools, to some extent making up for the larger number of children per staff member in comparison to private and voluntary settings. A comparison of data before and after substantial UK policy change between 1999 and 2014, aimed at increasing uptake and improving the quality of early years education and care, sugge

14h

Tesla’s Deep Learning at Scale: Using Billions of Miles to Train Neural Networks

submitted by /u/elemental_pineapple [link] [comments]

14h

14h

14h

14h

Apple and Google remove dating apps FTC says expose children to predators

Three Ukrainian-owned dating apps were yanked from Apple and Google app stores after the United States government found they potentially violated a federal law involving minors.

14h

Dollywood mannequin recycling tackles throwaway society

About 10,000 dummies and body parts are piled up at the creepy recycling centre.

14h

Rigspolitiet vil udveksle fingeraftryk fra danske pas med andre EU-lande

I løbet af 2019 vil Rigspolitiet begynde at udveksle fingeraftryksdata fra danske pas med andre EU-lande.

15h

Ingeniører er guld værd for startups

Startup-virksomheder, der baserer forretningsgrundlaget på teknisk viden, giver andre akademikervirksomheder baghjul, viser ny stor undersøgelse.

15h

It's people, not technology, that will decide the future of work

submitted by /u/POMCube [link] [comments]

15h

15h

Don’t let industry write the rules for AI

submitted by /u/TsukiZombina [link] [comments]

15h

15h

The new space race – podcast

The science writer Philip Ball has always been fascinated by space. He looks at the latest missions to the moon and beyond. And: Carole Cadwalladr on why she used her TED talk to tell tech billionaires they had broken democracy Philip Ball was a child when, in 1969, he watched Apollo 11 land the first two people on the moon. He has retained his fascination for space ever since and has been closel

16h

16h

Transplanting gut bacteria alters depression-related behavior, brain inflammation in animals

Scientists have shown that transplanting gut bacteria, from an animal that is vulnerable to social stress to a non-stressed animal, can cause vulnerable behavior in the recipient. The research reveals details of biological interactions between the brain and gut that may someday lead to probiotic treatments for human psychiatric disorders such as depression.

17h

New molecule maps cerebrovascular system

A peptide is capable of binding to the blood-brain barrier that protects the central nervous system and could help create novel imaging tests to diagnose Alzheimer's and Parkinson's.

17h

Ayahuasca fixings found in 1,000-year-old bundle in the Andes

Today's hipster creatives and entrepreneurs are hardly the first generation to partake of ayahuasca, according to archaeologists who have discovered traces of the powerfully hallucinogenic potion in a 1,000-year-old leather bundle buried in a cave in the Bolivian Andes.

17h

Genetic adaptation to climate change

New research has shown that the threat of range losses for some species as a result of climate change could be overestimated because of the ability of certain animals to adapt to rising temperatures and aridity.

17h

17h

Tiny droplets open the doors to in-flight imaging of proteins

For the first time, researchers have demonstrated the creation of a beam of nanodroplets capable of delivering a variety of biological samples, from cell organelles to single proteins, virtually free from any contaminations, to the focus of an X-ray laser which can be used to image them.

17h

Huntington drug successfully lowers levels of disease-causing protein, study shows

An international clinical trial has found that a new drug for Huntington disease is safe, and that treatment with the drug successfully lowers levels of the abnormal protein that causes the debilitating disease in patients.

17h

'Impossible' research produces 400-year El Niño record, revealing startling changes

Coral experts around the world said it was impossible to extract a multi-century record of El Niño events. But now a persistent effort has produced the world's first 400-year long record of El Niño events. And the changes researchers have found to El Niños in recent decades are startling.

17h

New 3-foot-tall relative of Tyrannosaurus rex

'Suskityrannus gives us a glimpse into the evolution of tyrannosaurs just before they take over the planet,' said Sterling Nesbit.

17h

Banana disease boosted by climate change

Climate change has raised the risk of a fungal disease that ravages banana crops, new research shows.

17h

Dataset bridges human vision and machine learning

Neuroscientists and computer vision scientists say a new dataset of unprecedented size — comprising brain scans of four volunteers who each viewed 5,000 images — will help researchers better understand how the brain processes images.

17h

Filming how our immune system kills bacteria

To kill bacteria in the blood, our immune system relies on nanomachines that can open deadly holes in their targets. Scientists have now filmed these nanomachines in action, discovering a key bottleneck in the process which helps to protect our own cells.

17h

The winter weather window that is costing rapeseed growers millions

Rapeseed growers are losing up to a quarter of their crop yield each year because of temperature rises during an early-winter weather window.

17h

17h

Breakthrough Discovery Recycles Plastic From the Inside Out

submitted by /u/thinkB4WeSpeak [link] [comments]

17h

Instagram's Newest Star Is … a Tree?

submitted by /u/tubbsmackinze [link] [comments]

17h

Department of Energy on collision course with end of Moore’s Law

submitted by /u/izumi3682 [link] [comments]

17h

Brain differences in blind people may sharpen hearing

New research identifies two differences in the brains of blind people that might be responsible for their abilities to make better use of auditory information. Studies have shown that people who are born blind or become blind early in life often have a more nuanced sense of hearing, especially when it comes to musical abilities and tracking moving objects in space (imagine crossing a busy road us

17h

Rice husks can remove microcystin toxins from water

An abundant and inexpensive agricultural byproduct, rice husks have been investigated as a water purification solution in the past. This is the first time they have been shown to remove microcystin, the toxin released by harmful algal blooms that are increasingly occurring in the Great Lakes and other freshwater lakes around the world.

17h

Tiny droplets open the doors to in-flight imaging of proteins

For the first time, researchers have demonstrated the creation of a beam of nanodroplets capable of delivering a variety of biological samples, from cell organelles to single proteins, virtually free from any contaminations, to the focus of an X-ray laser which can be used to image them.

17h

Trophy hunting: Gove 'cautious' over ban on imports

The environment secretary said wildlife charities had advised him to "be cautious".

17h

Could Air Conditioners Help Cool the Planet?

Researchers want to outfit air conditioners with carbon capture technology. Christopher Intagliata reports.

18h

Prison tobacco ban significantly reduces secondhand smoke

Levels of secondhand smoke in Scotland's prisons fell by more than 80% in the week after smoking was banned, according to new University of Stirling research.

18h

18h

The Atlantic Daily: Seventh in Line to the Throne

What We’re Following (Hannah Mckay / Reuters) The new royal baby will be seventh in line for the British throne. Meghan Markle and Prince Harry welcomed their first child today, and while the arrival of any new member of the royal family always spurs months of hubbub and paparazzi, this birth is of special historical significance: It’s the first interracial birth in the monarchy’s recent history

18h

Good surprises boost memories of specific events

Instances in which outcomes are better than we expect—finding an unexpectedly good parking spot, for example, or spotting a $20 bill on the sidewalk—improve memories of specific events, according to new research. This is in addition to the long-established role that unexpectedly good outcomes have in influencing what scientists call integrated memories. Remembering where you parked your car this

19h

Sunscreen in Your Bloodstream, Google’s Conference, and More News

Catch up on the most important news today in 2 minutes or less.

19h

Merging cell datasets, panorama style

A new algorithm takes cues from panoramic photography to merge massive, diverse cell datasets into a single source that can be used for medical and biological studies.

19h

Sound Justice: Citizen Science, Noise, and the Quest for Equity

At the start of World War I, thousands of soldiers were coming down with a baffling condition: they became blind, deaf, lost their memory, or developed uncontrollable shaking despite no obvious physical injury. Even stranger, this malady could be triggered by memories of the war even after the fighting had ended. At the time, doctors called what they were seeing “shell-shock,” though today we woul

19h