Jupiter's moon Europa has been the subject of intense study ever since the Voyager probes sent back images of its cracked, icy surface. There's a strong possibility Europa has a subsurface liquid ocean. Some observations have shown geysers erupting from the moon, but we haven't been able to verify there was water there until now. NASA's Goddard Space Flight Center confirms water vapor bursting fo
One of the most difficult problems facing first-world countries as they search for more environmentally sustainable manufacturing methods is the issue of fossil fuel use in heavy industry. According to a Bill Gates-backed startup, Heliogen, it's solved a major problem with industrial manufacturing and developed solar technology that can replace the conventional fossil fuels often used in these ty
Not exactly the pool you'd like to dive into. (Bryan Rodriguez via Unsplash/) A backpacker hikes through the woods, feet crunching through snow, working up a sweat as she trudges miles into the wilderness to set up camp. In the evening, with her clothes still damp from the day's exertion, she can't stop shivering and her muscles grow stiff. A cross-country skier glides through a winter wonderland
Scientists are reporting the first evidence that genetically edited cells could be safely helping a patient with sickle cell disease. The cells are producing a crucial oxygen-carrying protein.
Metal copper from agricultural runoff and marine paint leaching from boat hulls poses an emerging threat to soft coral sea fans in the waters around Puerto Rico.
Iowa State astronomers are part of an international team that has been analyzing data from NASA's TESS Mission. The astronomers describe their study of two red-giant stars — older, 'retired' stars no longer burning hydrogen in their cores — in a paper recently published by The Astrophysical Journal. The study details an interesting case of planetary evolution and demonstrates how star studies ca
Raining Down A team of scientists says it's found sugar molecules — crucial to the development of life on Earth — in two different fallen meteorites. The discovery suggests that meteor impacts may have delivered the sugars to Earth, per a NASA press release . One of the sugars is the RNA component ribose, a key biological building block, and the discovery that it may have come from space complica
Last week, scientists from the National Institute of Standards and Technology (NIST), the National Aeronautics and Space Administration (NASA), the United States Geological Survey (USGS) and the University of Guelph sent a telescope to the top of the sky, almost to space itself. The trip was a moonlight-gathering mission that has yielded some of the best measurements ever taken of the brightness,
Diagenode, Inc., a leading global provider of solutions for epigenetics research and sample preparation, and Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global leader in life science research and clinical diagnostic products, today announced a partnership in which Diagenode will offer Single-Cell ATAC-Seq (scATAC-Seq) Services, featuring Bio-Rad's Droplet Digital PCR technology, to help adv
Metal copper from agricultural runoff and marine paint leaching from boat hulls poses an emerging threat to soft coral sea fans in the waters around Puerto Rico.
Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) today announced the launch of EveryBlot Blocking Buffer, a western blot blocking reagent that offers 5-minute blocking time and produces higher signal and lower background levels resulting in greater sensitivity for western blots compared to other available blocking buffers.
Android camera security threat, disclosed and since addressed, had spy vulnerabilities. These were fixed by Google and Samsung with a patch rolled out for Pixel and Samsung devices The recent …
There are more than 10,000 nuclear weapons in existence today, each one capable of causing immense destruction. Why don't we talk about this threat as much as some other major issues? In this practical talk, nuclear security expert Emma Belcher shares three questions you can ask your elected officials to gain a better understanding of nuclear weapons and the measures we need to stay safe.
Scientists now believe that the primary culprit in this health crisis is vitamin E acetate, though research continues for other toxic factors. Vitamin E is a gooey thickener often used in black-market cannabis-based vaping products. Vapers who feel like they may have pneumonia should consult a physician immediately. None Surgeons are not squeamish people, so when one of them says , "This is an ev
Whether controlled fires reduce tick populations is still somewhat controversial. The conflagration physically kills most ticks, but the question lies in how quickly populations are able to rebound. People hate ticks. In fact, they hate them so much that folks are willing to deal with the hazards that accompany fire, like smoke, in order to reduce their populations. That's what Pennsylvania State
New research at Case Western Reserve University found big gaps in services and continued care for children with autism — and their families — as they transition from adolescence to adulthood.
A new study published in Health Services Research and led by a Boston University School of Public Health (BUSPH) researcher finds that, in the first year and a half of the program, children with mental health diagnoses who were served by the TEAM UP sites went for more primary care visits than similar children served by nearby non-participating community health centers.
Survivors of sepsis — a life-threatening response to an infection — have expressed a need for advocacy and follow-up support, according to a study authored by professors at the University of Tennessee, Knoxville, and the University of Tennessee Health Science Center in Memphis, and published in Dimensions of Critical Care Nursing.
E-meditation combines meditation with a low-level electrical stimulation that activates areas of the brain associated with meditation. Previous studies have suggested the combination of meditation and brain stimulation leads to reduced stress. At the Joint Meeting of Neuromodulation, Medical University of South Carolina researchers reported results from a study conducted during a five-day meditati
selected abstracts from the 30th Great Wall International Cardiology (GW-ICC) Conference, Beijing, China, October 10 – 13, 2019 Beijing, November 19, 2019: Cardiovascular Innovations and Applications (CVIA), in its role as the official journal of the Great Wall International Cardiology Conference (GW-ICC), has published selected abstracts from the 30th GW-ICC. The abstracts are now online at http
If you're looking for a new and green strategy game for your collection, the people at Blue Orange Games have just the thing. It's called Photosynthesis , and it puts two-to-four players in control of their own living forests, planting trees and guiding them through their life-cycles from tiny seeds all the way through full bloom and the cyclical process known as rebirth. Described as "the evergr
Gender identity and gender-typed preferences manifest similarly in both cis- and transgender children, even those who recently transitioned, research finds. Children who identify as the gender matching their sex at birth tend to gravitate toward the toys, clothing, and friendships stereotypically associated with that gender. Transgender children do the same with their gender, regardless of how lo
Metal copper from agricultural runoff and marine paint leaching from boat hulls poses an emerging threat to soft coral sea fans in the waters around Puerto Rico.
A study from Arizona State University and the University of Denver has validated a new statistical model that uses multiple standardized test scores over time to predict future academic performance. The dynamic measurement model accurately predicted academic performance decades in the future, and the predictions were three times better than current assessment methods. The model can be implemented
New research from University of Pennsylvania, University of California, San Diego and Yale University shows Donald Trump's 2016 presidential campaign didn't benefit from voters' fears of immigrants in communities experiencing greater demographic change, a finding that surprised even the political scientists who conducted the study, including Penn political scientist Daniel J. Hopkins.
This week, Macy's announced customers who used its website to make purchases between October 7 and October 15, 2019 could have had their personal information stolen by hackers.
Nature, Published online: 19 November 2019; doi:10.1038/d41586-019-03571-8 Marine scientist turned aquaculturalist discusses how she moved from the laboratory to an oyster farm.
Some "canaries" are 50 feet long, weigh 70 tons, and are nowhere near a coal mine. But the highly endangered North Atlantic right whale is sending the same kind of message about disruptive change in the environment by rapidly altering its use of important habitat areas off the New England coast. These findings are contained in a new study published in Global Change Biology by scientists at the Cen
While parents with substance use disorders are more likely to treat their children harshly, they don't do so all the time. What are the triggers? And how can substance-dependent mothers and their medical care providers predict difficulties across challenging parenting contexts?
Some "canaries" are 50 feet long, weigh 70 tons, and are nowhere near a coal mine. But the highly endangered North Atlantic right whale is sending the same kind of message about disruptive change in the environment by rapidly altering its use of important habitat areas off the New England coast. These findings are contained in a new study published in Global Change Biology by scientists at the Cen
Just Ugh People are using advanced modeling technology to create, sell, and have virtual sex with 3D avatars of celebrities or — disturbingly — their ex-partners. The porn is made created by 3D-rendering software like Virt-A-Mate and Foto2vam and shared or sold over sites like Reddit and Patreon, Motherboard reports . A booming marketplace already exists for 3D models of celebrities like Emilia C
Some 'canaries' are 50 feet long, weigh 70 tons, and are nowhere near a coal mine. But the highly endangered North Atlantic right whale is sending the same kind of message about disruptive change in the environment by rapidly altering its use of important habitat areas off the New England coast.
Researchers can now identify T cells reactive to a particular target from a patient's cells, and to perform high-throughput single-cell RNA sequencing of those cells.
Patients and medical providers should be aware that chronic opioid use can interfere with sleep by reducing sleep efficiency and increasing the risk of sleep-disordered breathing.
For those using illicit opioids to manage their chronic pain, cannabis may be a beneficial — and a less dangerous — alternative, according to new research.
Neurons that produce the neurotransmitter dopamine communicate with T cells to enhance allergic inflammation in the lungs of young mice but not older mice, researchers report. The findings potentially explain why asthma susceptibility is higher in children. By highlighting the important role of interactions between the nervous system and the immune system in childhood asthma, the results could lea
Ochre was often used as a vivid red paint in ancient rock art known as pictographs. Despite its broad use throughout human history and a modern focus on how the artistic symbolism is interpreted, little research exists on the paint itself and how it was produced. Now, scientists are using electron microscopes to understand how ochre paint was created by hunter-gatherers in North America to produce
The gas turbines powering aircraft engines rely on ceramic coatings that ensure structural stability at high temperatures. But these coatings don't control heat radiation, limiting the performance of the engine.
A fleet of commercial landers may be making their way to the moon in the coming years. (Tyvak Nano-Satellite Systems Inc /) NASA has set the ambitious ( some might say aspirational ) goal of sending a crew to the moon in 2024, but this time it doesn't want to go alone. On Monday, the agency announced that five new companies will be joining its lunar support posse: SpaceX, Blue Origin, Sierra Neva
By the time they reach adulthood, one in four South African girls will have contracted the HIV virus. Experiencing depression puts these girls at even higher risk of infection, reveals analyses led by researchers at the University of California, Berkeley, The findings, which appear in the American Journal of Epidemiology, suggest that interventions targeted at improving mental health among adolesc
Some 'canaries' are 50 feet long, weigh 70 tons, and are nowhere near a coal mine. But the highly endangered North Atlantic right whale is sending the same kind of message about disruptive change in the environment by rapidly altering its use of important habitat areas off the New England coast.
Patients and medical providers should be aware that chronic opioid use can interfere with sleep by reducing sleep efficiency and increasing the risk of sleep-disordered breathing, according to a position statement from the American Academy of Sleep Medicine.
MIT researchers can now identify T cells reactive to a particular target from a patient's cells, and to perform high-throughput single-cell RNA sequencing of those cells.
Bad Trip In September 2018, enigmatic billionaire Elon Musk made an eyebrow-raising appearance on the Joe Rogan podcast. During the two-hour conversation, Rogan offered him a puff of marijuana — an otherwise harmless decision that got his space company SpaceX, and Tesla , into a lot of trouble . SpaceX had to undergo an extremely thorough and expensive safety investigation by NASA after Musk's st
A new study finds that while the current United States administration's policies in Africa may appear undeveloped, there are distinct trends and tendencies that have the potential to negatively impact Africa's economic growth.
Researchers investigate and describe the conservation importance of buildings relative to natural, alternative roosts for little brown bats in Yellowstone National Park.
Yoga and physical therapy (PT) are effective approaches to treating co-occurring sleep disturbance and back pain while reducing the need for medication, according to a new study. The research showed significant improvements in sleep quality lasting 52 weeks after 12 weeks of yoga classes or 1-on-1 PT, which suggests a long-term benefit of these non-pharmacologic approaches.
Husbands are least stressed when their wives earn up to 40% of household income but they become increasingly uncomfortable as their spouse's wages rise beyond that point.
Finding Cracks Simulation theory, the hypothesis that we're just avatars in a simulated universe , has a new advocate. Speaking at a film festival, University of North Carolina at Wilmington computer scientist Curry Guinn suggested that our world isn't real, according to WRAL TechWire . Though Guinn admitted that it was a fairly speculative idea, he went on to argue that reports of ghosts, déjà v
A UC Davis study found that Lactobacillus plantarum bacteria rapidly repaired damaged gut lining (known as leaky gut) in monkeys infected with chronic simian immunodeficiency virus (SIV), an HIV-like virus. It linked chronically inflamed leaky gut to the loss of PPARα signaling and damage to mitochondria.
For those using illicit opioids to manage their chronic pain, cannabis may be a beneficial — and a less dangerous — alternative, according to new research from the BC Centre on Substance Use (BCCSU).
Covering your eyes, airways, and skin is critical for tear gas protection. Naval attire is optional. (Ale_Mi via Deposit Photos/) Anyone who has ever followed the news knows peaceful protests and demonstrations can quickly turn into dangerous affairs. When this happens, the result is nearly always the same: protesters get stuck in a thick, choking cloud of tear gas. This may sound like something
In 1987, a huge nearby supernova stunned astronomers. The explosion should have left behind a neutron star, but nobody has ever been able to find it until now
The cover for issue 62 of Oncotarget features Figure 7, 'Proposed model of the hyperploid pathway as a salvage survival strategy regulated by the G2-M checkpoint,' by Yeung, et al.
A new study finds that while the current United States administration's policies in Africa may appear undeveloped, there are distinct trends and tendencies that have the potential to negatively impact Africa's economic growth.
The University of Barcelona (UB) and Hospital Clínic de Barcelona collaborate with Boehringer Ingelheim Inc. to improve the efficiency of nintedanib, an antiangiogenic and antifibrotic drug, for the treatment of lung cancer. This public-private collaboration enabled researchers identify molecular mechanisms underlying the lack of efficiency of this drug in squamous cell carcinoma, a sub-type of no
Here the research team tested a safe and well-established microbe-based immune adjuvant to restore immune homeostasis and counteract inflammation-associated obesity in animal models.
Controlling synthetic protocells' movement toward and away from chemical signals could pave the way for drug delivery that better targets specific locations in the body. By coating the surface of the protocells with enzymes—proteins that catalyze chemical reactions—researchers could control the direction of the protocell's movement in a chemical gradient in a microfluidic device. "The futuristic
Nature, Published online: 19 November 2019; doi:10.1038/d41586-019-03562-9 A bacterium that infects a wealth of crops and ornamental plants landed in Europe from California.
That old sinking feeling is back. There have occasionally been stretches of time that are good for the Trump administration. There have more often been stretches that are bad, though there is a baseline of chaos that has come to feel almost normal. And occasionally, there have been truly hellacious stretches: May 2017 , when Donald Trump fired then–FBI Director James Comey; August 2017 , around t
Ochre, one of Earth's oldest naturally occurring materials, was often used as a vivid red paint in ancient rock art known as pictographs across the world. Despite its broad use throughout human history and a modern focus on how the artistic symbolism is interpreted, little research exists on the paint itself and how it was produced.
For the past decade, as inexpensive laser pointers have become more available, protesters around the world have added them to their tool kits. They are used to distract or obstruct riot police and their cameras and drones, as a colorful way to celebrate and show solidarity in groups, or as a method of communication. Recently, in Hong Kong, police officers have arrested people for the possession o
Even trash talk from a robot throws people off their game, research finds. The trash talk in the study was decidedly mild, with utterances like, "I have to say you are a terrible player," and "Over the course of the game your playing has become confused." Even so, people who played a game with the robot—a commercially available humanoid robot known as Pepper—performed worse when the robot discour
A study's findings add to the case that lichens, which dominate about 7 percent of the planet's surface, most likely made their way to land some 100 million years after ferns and other vascular plants.
Ochre was often used as a vivid red paint in ancient rock art known as pictographs. Despite its broad use throughout human history and a modern focus on how the artistic symbolism is interpreted, little research exists on the paint itself and how it was produced. Now, scientists are using electron microscopes to understand how ochre paint was created by hunter-gatherers in North America to produce
Hepatic encephalopathy (HE) is a reversible complication of liver cirrhosis thought to be caused by ammonia and is typically treated with lactulose. Researchers at the Medical University of South Carolina conducted a cohort study that examined the correlation of ammonia levels with lactulose treatment. They found no correlation between ammonia level and dose of lactulose given. They concluded that
University of Colorado Cancer Center study shows that while the use of new, high-cost lung cancer drugs rose 27 percent from 2007 to 2015, they are not used equally in all places, with all patients. Patients who lived in high-poverty areas were 4 percent less likely to be treated with high-cost lung cancer drugs, while patients treated at National Cancer Institute-designated cancer centers were 10
Two clinical trial participants–one with beta-thalassemia and one with sickle cell disease–appeared to benefit from the gene-editing treatments with minimal side effects, according to the companies.
The US-born giant panda Bei Bei on Tuesday left the only home he has known at the National Zoo in Washington for a 16-hour flight back to China as part of its research and breeding program.
Hand-dug trenches around Leigh Lake in Grand Teton National Park in Wyoming reveal evidence for a previously unknown surface-faulting earthquake in along the Teton Fault—one occurring about 10,000 years ago.
The US-born giant panda Bei Bei on Tuesday left the only home he has known at the National Zoo in Washington for a 16-hour flight back to China as part of its research and breeding program.
As scientists scramble to determine whether there is life on Mars, Ohio University Professor Emeritus William Romoser's research shows that we already have the evidence, courtesy of photographs from various Mars rovers.
For the little brown bat—a small mouse-eared bat with glossy brown fur—a warm, dry place to roost is essential to the species' survival. Reproductive females huddle their small furry bodies together to save thermal energy during maternity season (summer), forming "maternity colonies." In the face of severe population losses across North America, summer access to an attic or other permanent shelter
Vehicles moving at hypersonic speeds are bombarded with ice crystals and dust particles in the surrounding atmosphere, making the surface material vulnerable to damage such as erosion and sputtering with each tiny collision. Researchers at the University of Illinois at Urbana-Champaign studied this interaction one molecule at a time to understand the processes, then scaled up the data to make it c
For the little brown bat—a small mouse-eared bat with glossy brown fur—a warm, dry place to roost is essential to the species' survival. Reproductive females huddle their small furry bodies together to save thermal energy during maternity season (summer), forming "maternity colonies." In the face of severe population losses across North America, summer access to an attic or other permanent shelter
Love those dainty little bottles of shampoo, conditioner and hand lotion in hotel bathrooms? Do you take them home, use them for guests or donate them to the local homeless shelter? You won't be able to for much longer—states, localities and some hotel chains are scrapping the tiny amenities.
L ast week's Republican rallying cry on impeachment was "Hearsay!" By this morning, the focus had turned back to the whistle-blower who started it all. The consensus GOP retort to the first three public witnesses in the House impeachment inquiry—Ambassadors William Taylor and Marie Yovanovitch, and George Kent, a deputy secretary of state—was that none of them had direct, firsthand knowledge of P
Vehicles moving at hypersonic speeds are bombarded with ice crystals and dust particles in the surrounding atmosphere, making the surface material vulnerable to damage such as erosion and sputtering with each tiny collision. Researchers studied this interaction one molecule at a time to understand the processes, then scaled up the data to make it compatible with simulations that require a larger s
Hand-dug trenches around Leigh Lake in Grand Teton National Park in Wyoming reveal evidence for a previously unknown surface-faulting earthquake in along the Teton Fault — one occurring about 10,000 years ago.
Fear of clusters of holes and cracks, called trypophobia, may be evolutionary in origin. But as details are shared, it is becoming a social contagion. By Chrissie Giles Julia was around 11 years old the first time it happened. She let herself into her dad's apartment in Malmö, Sweden, dropped her schoolbag and flopped on to the sofa. She switched on the TV and turned to her favourite channel in t
The McLaren Elva lacks a windscreen and a roof. (McLaren/) Elva Cars Ltd. is a mostly forgotten member of the British cottage sports car fraternity of the 1960s, like TVR, Sunbeam and Morgan. But the company had the distinction of building the first roadgoing McLaren when it adapted the open cockpit McLaren M1A sports racer into the McLaren-Elva M1A in 1964. Interest was high for a street version
Nature, Published online: 19 November 2019; doi:10.1038/d41586-019-03574-5 Scientists fear the controversy over the Nightingale project will undermine trust in research.
Laser Focus A Bill Gates-backed startup called Heliogen just unveiled new technology that could help make the manufacturing industry carbon neutral. Heliogen used an artificial intelligence algorithm to position a massive array of mirrors so that they all redirected sunlight onto a single point — heating it to over 1,000 degrees Celsius, according to CNN , which is about a quarter of the temperat
Vehicles moving at hypersonic speeds are bombarded with ice crystals and dust particles in the surrounding atmosphere, making the surface material vulnerable to damage such as erosion and sputtering with each tiny collision. Researchers studied this interaction one molecule at a time to understand the processes, then scaled up the data to make it compatible with simulations that require a larger s
As scientists scramble to determine whether there is life on Mars, Ohio University Professor Emeritus William Romoser's research shows that we already have the evidence.
New research at Washington State University has found that boredom is rising year after year for teens in 8th, 10th, and 12th grades, with greater increases for girls than boys.
Invasive procedures are no better than medications and lifestyle advice at treating heart disease that's severe but stable, according to new research. The clinical trial did show, however, that among patients with coronary artery disease who also had symptoms of angina—chest pain that restricted blood flow to the heart causes—treatment with invasive procedures, such as stents or bypass surgery, w
Wilson (1) proposes a multiple testing procedure based on the harmonic mean p-value (HMP). While this is a potentially useful method, he makes several claims that are not supported by the theory. Herein we identify 4 errors, for clarity described in terms of the version with equal weights 1/L, so…
There were 2 errors in Wilson (1) which I have announced, but I do not accept the 4 claimed by Goeman et al. (2); I rebut them point by point on a figshare page (https://figshare.com/articles/Trade-offs_in_model_averaging_using_multilevel_tests_Appendix_/9699740). However, their letter highlights 2 limitations of the harmonic mean p-value (HMP) procedure that I…
The genes in the human leukocyte antigen (HLA) (human major histocompatibility complex [MHC]) complex are iconic examples of balancing selection (1–3). Two important HLA signatures, the retention of alleles, polymorphism, and haplotypes over evolutionary time, known as transspecies polymorphism, and dN/dS > 1 and the related high polymorphism at functionally…
We have recently shown in 2 large-scale surveys (1, 2) that human leukocyte antigen (HLA) haplotypes frequency distributions are better characterized by purifying selection than by balancing selection. In their Letter, Hedrick and Klitz claim that the HLA locus is a classical example of balancing selection and that our recent…
The interface between electron-donating (D) and electron-accepting (A) materials in organic photovoltaic (OPV) devices is commonly probed by charge-transfer (CT) electroluminescence (EL) measurements to estimate the CT energy, which critically relates to device open-circuit voltage. It is generally assumed that during CT-EL injected charges recombine at close-to-equilibrium energies in their…
Mitochondrial superoxide dismutase (SOD2) suppresses tumor initiation but promotes invasion and dissemination of tumor cells at later stages of the disease. The mechanism of this functional switch remains poorly defined. Our results indicate that as SOD2 expression increases acetylation of lysine 68 ensues. Acetylated SOD2 promotes hypoxic signaling via increased…
Primary cilia carry out numerous signaling and sensory functions, and defects in them, "ciliopathies," cause a range of symptoms, including blindness. Understanding of their nanometer-scale ciliary substructures and their disruptions in ciliopathies has been hindered by limitations of conventional microscopic techniques. We have combined cryoelectron tomography, enhanced by subtomogram averaging,.
To understand the impact reduced mercury (Hg) loading and invasive species have had on methylmercury bioaccumulation in predator fish of Lake Michigan, we reconstructed bioaccumulation trends from a fish archive (1978 to 2012). By measuring fish Hg stable isotope ratios, we related temporal changes in Hg concentrations to varying Hg…
Iron uptake by diatoms is a biochemical process with global biogeochemical implications. In large regions of the surface ocean diatoms are both responsible for the majority of primary production and frequently experiencing iron limitation of growth. The strategies used by these phytoplankton to extract iron from seawater constrain carbon flux…
The impact of intratumoral heterogeneity (ITH) and the resultant neoantigen landscape on T cell immunity are poorly understood. ITH is a widely recognized feature of solid tumors and poses distinct challenges related to the development of effective therapeutic strategies, including cancer neoantigen vaccines. Here, we performed deep targeted DNA sequencing…
Invariant NKT (iNKT) cells have the unique ability to shape immunity during antitumor immune responses and other forms of sterile and nonsterile inflammation. Recent studies have highlighted a variety of classes of endogenous and pathogen-derived lipid antigens that can trigger iNKT cell activation under sterile and nonsterile conditions. However, the…
Following antigen stimulation, naïve T cells differentiate into memory cells that mediate antigen clearance more efficiently upon repeat encounter. Donor-specific tolerance can be achieved in a subset of transplant recipients, but some of these grafts are rejected after years of stability, often following infections. Whether T cell memory can develop…
Inflammation plays an important role in pathological angiogenesis. Receptor-interacting protein 1 (RIP1) is highly expressed in inflammatory cells and is known to play an important role in the regulation of apoptosis, necroptosis, and inflammation; however, a comprehensive description of its role in angiogenesis remains elusive. Here, we show that RIP1…
Tumor-associated myeloid cells (TAMCs) are key drivers of immunosuppression in the tumor microenvironment, which profoundly impedes the clinical response to immune-dependent and conventional therapeutic modalities. As a hallmark of glioblastoma (GBM), TAMCs are massively recruited to reach up to 50% of the brain tumor mass. Therefore, they have recently been…
The early stages of age-related macular degeneration (AMD) are characterized by the accumulation of basal laminar deposits (BLamDs). The mechanism for BLamDs accumulating between the retinal pigment epithelium (RPE) and its basal lamina remains elusive. Here we examined the role in AMD of lysosome-associated membrane protein-2 (LAMP2), a glycoprotein that…
From incoming sensory information, our brains make selections according to current behavioral goals. This process, selective attention, is controlled by parietal and frontal areas. Here, we show that another brain area, posterior inferotemporal cortex (PITd), also exhibits the defining properties of attentional control. We discovered this area with functional magnetic…
Regular physical exercise is the most efficient and accessible intervention known to promote healthy aging in humans. The molecular and cellular mechanisms that mediate system-wide exercise benefits, however, remain poorly understood, especially as applies to tissues that do not participate directly in training activity. The establishment of exercise protocols for…
Increasing maize grain yield has been a major focus of both plant breeding and genetic engineering to meet the global demand for food, feed, and industrial uses. We report that increasing and extending expression of a maize MADS-box transcription factor gene, zmm28, under the control of a moderate-constitutive maize promoter,…
Drone-mounted, high-resolution light detection and ranging reveals the architectural details of an ancient settlement on the Gulf Coast of Florida without parallel in the Southeastern United States. The Raleigh Island shell-ring complex (8LV293) of ca. 900 to 1200 CE consists of at least 37 residential spaces enclosed by ridges of…
Comorbidity is common as age increases, and currently prescribed treatments often ignore the interconnectedness of the involved age-related diseases. The presence of any one such disease usually increases the risk of having others, and new approaches will be more effective at increasing an individual's health span by taking this systems-level…
Message passing is a fundamental technique for performing calculations on networks and graphs with applications in physics, computer science, statistics, and machine learning, including Bayesian inference, spin models, satisfiability, graph partitioning, network epidemiology, and the calculation of matrix eigenvalues. Despite its wide use, however, it has long been recognized that…
Many cellular processes are governed by stochastic reaction events. These events do not necessarily occur in single steps of individual molecules, and, conversely, each birth or death of a macromolecule (e.g., protein) could involve several small reaction steps, creating a memory between individual events and thus leading to nonmarkovian reaction…
Phase transitions in halide perovskites triggered by external stimuli generate significantly different material properties, providing a great opportunity for broad applications. Here, we demonstrate an In-based, charge-ordered (In+/In3+) inorganic halide perovskite with the composition of Cs2In(I)In(III)Cl6 in which a pressure-driven semiconductor-to-metal phase transition exists. The single cryst
Among natural energy resources, methane clathrate has attracted tremendous attention because of its strong relevance to current energy and environment issues. Yet little is known about how the clathrate starts to nucleate and disintegrate at the molecular level, because such microscopic processes are difficult to probe experimentally. Using surface-specific sum-frequency…
As a central feature of neuroinflammation, microglial dysfunction has been increasingly considered a causative factor of neurodegeneration implicating an intertwined pathology with amyloidogenic proteins. Herein, we report the smallest synthetic molecule (N,N′-diacetyl-p-phenylenediamine [DAPPD]), simply composed of a benzene ring with 2 acetamide groups at the para position, known to date…
Pat1 is a hub for mRNA metabolism, acting in pre-mRNA splicing, translation repression, and mRNA decay. A critical step in all 5′-3′ mRNA decay pathways is removal of the 5′ cap structure, which precedes and permits digestion of the RNA body by conserved exonucleases. During bulk 5′-3′ decay, the Pat1/Lsm1-7…
Posttranslational protein modification by ubiquitin (Ub) is a central eukaryotic mechanism that regulates a plethora of physiological processes. Recent studies unveiled an unconventional type of ubiquitination mediated by the SidE family of Legionella pneumophila effectors, such as SdeA, that catalyzes the conjugation of Ub to a serine residue of target…
Telomeres cap the ends of linear chromosomes and terminate in a single-stranded DNA (ssDNA) overhang recognized by POT1-TPP1 heterodimers to help regulate telomere length homeostasis. Here hydroxyl radical footprinting coupled with mass spectrometry was employed to probe protein–protein interactions and conformational changes involved in the assembly of telomere ssDNA substrates…
Angiogenesis frequently occurs in the context of acute or persistent inflammation. The complex interplay of proinflammatory and proangiogenic cues is only partially understood. Using an experimental model, permitting exposure of developing blood vessel sprouts to multiple combinations of diverse biochemical stimuli and juxtacrine cell interactions, we present evidence that a…
The evolution and potentially even the survival of a spatially expanding population depends on its genetic diversity, which can decrease rapidly due to a serial founder effect. The strength of the founder effect is predicted to depend strongly on the details of the growth dynamics. Here, we probe this dependence…
Membrane fusion at each organelle requires conserved proteins: Rab-GTPases, effector tethering complexes, Sec1/Munc18 (SM)-family SNARE chaperones, SNAREs of the R, Qa, Qb, and Qc families, and the Sec17/α-SNAP and ATP-dependent Sec18/NSF SNARE chaperone system. The basis of organelle-specific fusion, which is essential for accurate protein compartmentation, has been elusive. Rab…
Antibiotic resistance has become one of the major threats to global health. Photodynamic inactivation (PDI) develops little antibiotic resistance; thus, it becomes a promising strategy in the control of bacterial infection. During a PDI process, light-induced reactive oxygen species (ROS) damage the membrane components, leading to the membrane rupture and…
Ammonia is special. It is nonplanar, yet in v = 1 of the umbrella mode (ν2) its inversion motion is faster than J = 0↔1 rotation. Does the simplicity of the Chemist's concept of an electric dipole moment survive the competition between rotation, inversion, and a strong external electric field?…
Information concerning the dynamics of river meandering is embedded in their planforms. Here, we focus on how bend skewing varies with increasing sinuosity, and how flow direction is embedded in bend skewing. It has often been thought that upstream-skewed bends are dominant within a sufficiently long reach. These bends may…
The southern westerly wind belt (SWW) interacts with the Antarctic Circumpolar Current and strongly impacts the Southern Ocean carbon budget, and Antarctic ice-sheet dynamics across glacial–interglacial cycles. We investigated precipitation-driven sediment input changes to the Southeast Pacific off the southern margin of the Atacama Desert over the past one million…
Chondritic meteorites are composed of primitive components formed during the evolution of the Solar protoplanetary disk. The oldest of these components formed by condensation, yet little is known about their formation mechanism because of secondary heating processes that erased their primordial signature. Amoeboid Olivine Aggregates (AOAs) have never been melted…
A major challenge in biology is to understand how phylogeny, diet, and environment shape the mammalian gut microbiome. Yet most studies of nonhuman microbiomes have relied on relatively coarse dietary categorizations and have focused either on individual wild populations or on captive animals that are sheltered from environmental pressures, which…
We present a theory on the coalescence of 2 spherical liquid droplets that are initially stationary. The evolution of the radius of a liquid neck formed upon coalescence was formulated as an initial value problem and then solved to yield an exact solution without free parameters, with its 2 asymptotic…
Fire-prone invasive grasses create novel ecosystem threats by increasing fine-fuel loads and continuity, which can alter fire regimes. While the existence of an invasive grass-fire cycle is well known, evidence of altered fire regimes is typically based on local-scale studies or expert knowledge. Here, we quantify the effects of 12…
The layered oxide Na0.67CoO2 with Na+ occupying trigonal prismatic sites between CoO2 layers exhibits a remarkably high room temperature oxygen evolution reaction (OER) activity in alkaline solution. The high activity is attributed to an unusually short O–O separation that favors formation of peroxide ions by O−–O– interactions followed by O2…
Endothelial cells (ECs) are highly specialized across vascular beds. However, given their interspersed anatomic distribution, comprehensive characterization of the molecular basis for this heterogeneity in vivo has been limited. By applying endothelial-specific translating ribosome affinity purification (EC-TRAP) combined with high-throughput RNA sequencing analysis, we identified pan EC-enriched
Myocardin-related transcription factor B (MRTFB) is a candidate tumor-suppressor gene identified in transposon mutagenesis screens of the intestine, liver, and pancreas. Using a combination of cell-based assays, in vivo tumor xenograft assays, and Mrtfb knockout mice, we demonstrate here that MRTFB is a human and mouse colorectal cancer (CRC) tumor…
Sonic hedgehog (SHH) signaling plays a pivotal role in 2 different phases during brain development. Early SHH signaling derived from the prechordal plate (PrCP) triggers secondary Shh induction in the forebrain, which overlies the PrCP, and the induced SHH signaling, in turn, directs late neuronal differentiation of the forebrain. Consequently,…
The cross-talk between the microbiota and the immune system plays a fundamental role in the control of host physiology. However, the tissue-specific factors controlling this dialogue remain poorly understood. Here we demonstrate that T cell responses to commensal colonization are associated with the development of organized cellular clusters within the…
The activation of innate immune receptors by pathogen-associated molecular patterns (PAMPs) is central to host defense against infections. On the other hand, these receptors are also activated by immunogenic damage-associated molecular patterns (DAMPs), typically released from dying cells, and the activation can evoke chronic inflammatory or autoimmune disorders. One of…
Predictive biomarkers for tumor response to neoadjuvant chemotherapy are needed in breast cancer. This study investigates the predictive value of 280 genes encoding proteins that regulate microtubule assembly and function. By analyzing 3 independent multicenter randomized cohorts of breast cancer patients, we identified 17 genes that are differentially regulated in…
Pyrophosphate deficiency may explain the excessive vascular calcification found in children with Hutchinson–Gilford progeria syndrome (HGPS) and in a mouse model of this disease. The present study found that hydrolysis products of ATP resulted in a <9% yield of pyrophosphate in wild-type blood and aortas, showing that eNTPD activity (ATP…
Upon delivery into the nucleus of the host cell, linear double-stranded retroviral DNAs are either integrated into the host genome to form the provirus or act as a target of the DNA damage response and become circularized. Little is known about the chromatinization status of the unintegrated retroviral DNAs of…
Epidemiological studies show that maternal diabetes is associated with an increased risk of autism spectrum disorders (ASDs), although the detailed mechanisms remain unclear. The present study aims to investigate the potential effect of maternal diabetes on autism-like behavior in offspring. The results of in vitro study showed that transient hyperglycemia…
Young healthy adults can hear tones up to at least 20 kHz. However, clinical audiometry, by which hearing loss is diagnosed, is limited at high frequencies to 8 kHz. Evidence suggests there is salient information at extended high frequencies (EHFs; 8 to 20 kHz) that may influence speech intelligibility, but…
Elimination of dysfunctional mitochondria via mitophagy is essential for cell survival and neuronal functions. But, how impaired mitophagy participates in tissue-specific vulnerability in the brain remains unclear. Here, we find that striatal-enriched protein, Rhes, is a critical regulator of mitophagy and striatal vulnerability in brain. In vivo interactome and density…
The alpha rhythm is the longest-studied brain oscillation and has been theorized to play a key role in cognition. Still, its physiology is poorly understood. In this study, we used microelectrodes and macroelectrodes in surgical epilepsy patients to measure the intracortical and thalamic generators of the alpha rhythm during quiet…
Animal behavior is remarkably robust despite constant changes in neural activity. Homeostatic plasticity stabilizes central nervous system (CNS) function on time scales of hours to days. If and how CNS function is stabilized on more rapid time scales remains unknown. Here, we discovered that mossy fiber synapses in the mouse…
Carrying premature termination codons in 1 allele of the ABCA7 gene is associated with an increased risk for Alzheimer's disease (AD). While the primary function of ABCA7 is to regulate the transport of phospholipids and cholesterol, ABCA7 is also involved in maintaining homeostasis of the immune system. Since inflammatory pathways…
We show that it is possible to construct foam-based heterostructures with complete photonic band gaps. Three-dimensional foams are promising candidates for the self-organization of large photonic networks with combinations of physical characteristics that may be useful for applications. The largest band gap found is based on 3D Weaire–Phelan foam, a…
Shift work causes circadian misalignment and is a risk factor for obesity. While some characteristics of the human circadian system and energy metabolism differ between males and females, little is known about whether sex modulates circadian misalignment effects on energy homeostasis. Here we show—using a randomized cross-over design with two…
Ketone bodies, including β-hydroxybutyrate and acetoacetate, are important alternative energy sources during energy shortage. β-Hydroxybutyrate also acts as a signaling molecule via specific G protein-coupled receptors (GPCRs); however, the specific associated GPCRs and physiological functions of acetoacetate remain unknown. Here we identified acetoacetate as an endogenous agonist for short-chain
Nicotinamide adenine dinucleotide (NAD+) is a critical coenzyme for cellular energy metabolism. The aim of the present study was to determine the importance of brown and white adipose tissue (BAT and WAT) NAD+ metabolism in regulating whole-body thermogenesis and energy metabolism. Accordingly, we generated and analyzed adipocyte-specific nicotinamide phosphoribosyltransferase (Nampt)…
For the past 4 decades, intensive molecular studies of mostly leaf mesophyll cell-infecting pathogens and chewing insects have led to compelling models of plant–pathogen and plant–insect interactions. Yet, some of the most devastating pathogens and insect pests live in or feed on the phloem, a systemic tissue belonging to the…
The plant circadian clock evolved to increase fitness by synchronizing physiological processes with environmental oscillations. Crop fitness was artificially selected through domestication and breeding, and the circadian clock was identified by both natural and artificial selections as a key to improved fitness. Despite progress in Arabidopsis, our understanding of the…
When predicting success, how important are personal attributes other than cognitive ability? To address this question, we capitalized on a full decade of prospective, longitudinal data from n = 11,258 cadets entering training at the US Military Academy at West Point. Prior to training, cognitive ability was negatively correlated with…
The main contributors to sea-level rise (oceans, glaciers, and ice sheets) respond to climate change on timescales ranging from decades to millennia. A focus on the 21st century thus fails to provide a complete picture of the consequences of anthropogenic greenhouse gas emissions on future sea-level rise and its long-term…
BIOPHYSICS AND COMPUTATIONAL BIOLOGY Correction for "Capsid expansion of bacteriophage T5 revealed by high resolution cryoelectron microscopy," by Alexis Huet, Robert L. Duda, Pascale Boulanger, and James F. Conway, which was first published October 2, 2019; 10.1073/pnas.1909645116 (Proc. Natl. Acad. Sci. U.S.A. 116, 21037–21046). The authors note that, due to…
NEUROSCIENCE Correction for "Amyloid-beta impairs TOM1-mediated IL-1R1 signaling," by Alessandra Cadete Martini, Angela Gomez-Arboledas, Stefania Forner, Carlos J. Rodriguez-Ortiz, Amanda McQuade, Emma Danhash, Jimmy Phan, Dominic Javonillo, Jordan-Vu Ha, Melanie Tram, Laura Trujillo-Estrada, Celia da Cunha, Rahasson R. Ager, Jose C. Davila, Masashi Kitazawa, Mathew Blurton-Jones, Antonia Gutierre
PLANT BIOLOGY Correction for "Sugar starvation-regulated MYBS2 and 14-3-3 protein interactions enhance plant growth, stress tolerance, and grain weight in rice," by Yi-Shih Chen, Tuan-Hua David Ho, Lihong Liu, Ding Hua Lee, Chun-Hua Lee, Yi-Ru Chen, Shu-Yu Lin, Chung-An Lu, and Su-May Yu, which was first published October 8, 2019;…
PLANT BIOLOGY Correction for "Arabidopsis and Chlamydomonas phosphoribulokinase crystal structures complete the redox structural proteome of the Calvin–Benson cycle," by Libero Gurrieri, Alessandra Del Giudice, Nicola Demitri, Giuseppe Falini, Nicolae Viorel Pavel, Mirko Zaffagnini, Maurizio Polentarutti, Pierre Crozet, Christophe H. Marchand, Julien Henri, Paolo Trost, Stéphane D. Lemaire, France
Diet and gut microbiome of African megafauna Reticulated giraffe plucks a Hibiscus meyeri plant from within a clump of the shrub Croton dichogamus at the Mpala Research Centre in Kenya. Diet and gut microbiome composition are important for mammalian health, but their fluctuation in response to environmental changes is unclear….
Sheng Yang He has spent a distinguished career studying bacterial plant pathogens and the molecular mechanisms by which they lead to disease. A professor of plant biology at Michigan State University and a Howard Hughes Medical Institute investigator, He was elected to the National Academy of Sciences in 2015. He…
The emission of greenhouse gases into Earth's atmosphere is a by-product of modern marvels such as the production of vast amounts of energy, heating and cooling inhospitable environments to be amenable to human existence, and traveling great distances faster than our saddle-sore ancestors ever dreamed possible. However, these luxuries come…
Subsets of highly invasive, therapy-resistant tumor cells contribute to the development of metastasis and treatment failures. Recent evidence suggests that these tumor cell subsets are enriched for cancer stem cells (CSCs) (1–3). Similar to nonneoplastic stem cells, CSCs express specific markers and transcription factors and can self-renew or differentiate. For…
The idea that a spreading species can lose genetic diversity goes back to early work by Ernst Mayr in 1942 on founder effects for introduced populations (1). Here, reduced diversity of a spreading population arises from the small number of individuals who are initially introduced into a region (founders). A…
On March 1, 2010, the Kepler space telescope spotted a distant star brighten slightly. Compared with the ferocious intensity of a supernova or gamma-ray burst, this event was feeble. It was merely a stellar flare, and by no means the most powerful flare ever seen. Nevertheless, it was ominous. Fig….
Designer babies, or children who have been gene-hacked to develop certain traits, are coming soon. That's according to Abertay University bioethicist Kevin Smith, The Independen t reports . Smith argues that it's ethically responsible to gene-hack humans in research published in the journal Bioethics . He believes that scientists could, with existing technology, prevent diseases or improve people
A diet high in fiber and yogurt is associated with a reduced risk for lung cancer, according to a new study. The benefits of a diet high in fiber and yogurt have already been established for cardiovascular disease and gastrointestinal cancer. The new findings, based on an analysis of data from studies involving 1.4 million adults in the United States, Europe, and Asia, suggest this diet may also
Researchers have, for the first time, successfully demonstrated a formation and current-induced motion of synthetic antiferromagnetic magnetic skyrmions. The established findings are expected to pave the way towards new functional information processing and storage technologies.
Special light beams can be used to manipulate molecules or small biological particles. However, these optical tweezers only work with objects in empty space. Any disturbing environment would deflect the light waves and destroy the effect. This is a problem, in particular with biological samples. Now, a special method was developed to calculate the perfect wave form to manipulate small particles in
Children's Colorado researchers and their colleagues found that musculoskeletal pain, physical function and quality of life in adolescents significantly improves and is maintained three years after bariatric surgery. Knowing that bariatric surgery does come with the risk of long-term nutritional deficiencies, particularly involving iron and vitamin B12, Children's Colorado researchers and their co
The leftovers from a spectacular supernova that revolutionized our understanding of how stars end their lives have finally been spotted by astronomers.
Down syndrome, due to an extra chromosome 21, occurs in 250,000 children and adults in the United States, making it the country's most common chromosomal disorder. Inherited heart defects, thyroid cancer, celiac disease and developmental disabilities are common Down syndrome complications. Only recently has catatonia, a behavioral condition marked by new onset immobility, mutism, withdrawal and ot
Genetic analyses have revealed remarkably higher species diversity in common red seaweed than previously assumed. It was thought that there were only five related species of the Gloiopeltis genus worldwide. However, it has been revealed that there are over ten in Japan alone.
Researchers have, for the first time, successfully demonstrated a formation and current-induced motion of synthetic antiferromagnetic magnetic skyrmions. The established findings are expected to pave the way towards new functional information processing and storage technologies.
Using "Trojan horses" to combat cancer from within the tumour cells themselves without damaging healthy tissues is the aim of this new tool created by researchers from the University of Granada (UGR), the Institute of Nanoscience of Aragon (INA), the University of Zaragoza, and the Cancer Research UK Edinburgh Centre at the University of Edinburgh.
There has been a substantial increase in food production over the last 50 years, but it has been accompanied by a narrowing in the diversity of cultivated crops. New research shows that diversifying crop production can make food supplies more nutritious, reduce resource demand and greenhouse gas emissions, and enhance climate resilience without reducing calorie production or requiring more land.
The leftovers from a spectacular supernova that revolutionised our understanding of how stars end their lives have finally been spotted by astronomers at Cardiff University.
Gem of nature, moral hazard, or attractive nuisance? It's hard to miss the inherent tension in Welling & Abegg's Following the ice: adaptation processes of glacier tour operators in Southeast Iceland : The growing recognition that global climatic change is a pressing reality and that its impacts on humans and ecological systems are inevitable makes adaptation a core topic in climate change resear
If your ex secretly put a GPS tracker on your car and you found and removed it, the idea of them taking you to court for theft of the device would be laughable. But what if instead of an ex, it was a police officer that placed the tracker on your car because they thought you were dealing meth? That's the bizarre basis for a case currently being heard by the Indiana Supreme Court . The background:
Researchers investigate and describe the conservation importance of buildings relative to natural, alternative roosts for little brown bats in Yellowstone National Park.
Vehicles moving at hypersonic speeds are bombarded with ice crystals and dust particles in the surrounding atmosphere, making the surface material vulnerable to damage such as erosion and sputtering with each tiny collision. Researchers at the University of Illinois at Urbana-Champaign studied this interaction one molecule at a time to understand the processes, then scaled up the data to make it c
Managing reservoirs for water quality, not just flood control, could be part of the solution to the growth of toxic algal blooms in the Great Lakes, especially Lake Erie, every summer.
By understanding how, when, and why badgers move from one social group to another, researchers hope information gleaned from GPS devices will help them tailor vaccination programs to reduce the spread of bovine tuberculosis.
Special light beams can be used to manipulate molecules or small biological particles. However, these optical tweezers only work with objects in empty space. Any disturbing environment would deflect the light waves and destroy the effect. This is a problem, in particular with biological samples. Now, a special method was developed to calculate the perfect wave form to manipulate small particles in
A new group of symbiotic bacteria in deep-sea mussels surprises with the way they fix carbon: They use the Calvin cycle to turn carbon into tasty food. The bacteria acquired the genes for this process from neighboring symbiotic bacteria in the mussel. These results call into question our current understanding of carbon fixation pathways in the deep sea.
Wine researchers say their latest discovery may one day lead to winemakers being able to manipulate the acidity of wines without the costly addition of tartaric acid.
There has been a substantial increase in food production over the last 50 years, but it has been accompanied by a narrowing in the diversity of cultivated crops. New research shows that diversifying crop production can make food supply more nutritious, reduce resource demand and greenhouse gas emissions, and enhance climate resilience without reducing calorie production or requiring more land.
Artificial intelligence can be used to predict molecular wave functions and the electronic properties of molecules. This innovative AI method could be used to speed-up the design of drug molecules or new materials.
Scientists have successfully produced human tissues from stem cells. They have a complexity similar to that of normal tissue and are far superior to previous structures.
Nuclear RNA levels are kept in check by RNA decay factors. Now, researchers show that an excess of RNA in the nucleus can have negative effects on a crucial regulator of stem cell differentiation.
The biological sensors change color once they have successfully snared a target molecule, and will soon have a host of important environmental, medical and security applications.
Researchers have discovered striking variation in the underlying genetic machinery that orchestrates sexual differentiation in frogs, demonstrating that evolution of this crucial biological system has moved at a dramatic pace.
In Shock Elon Musk's spacetech company SpaceX is trying to bring broadband to the globe by sending up to 12,000 tiny satellites into low-Earth orbit. But not everybody is thrilled. Astronomers are finding that the 122 satellites SpaceX has launched so far are already ruining the night sky, showing up as extremely bright trails of light in observations. "Wow!! I am in shock!!," tweeted Clarae Mart
New technology devised by Tel Aviv University (TAU), Herzliyah Interdisciplinary (IDC) and Technion-Israel Institute of Technology researchers may soon offer an alternative to invasive and risky biopsies as a means of profiling tumor tissues.
Research from Florida State University is giving physicians a better understanding of ketamine, a potentially useful tool in treating depression that still has unanswered questions. A team of researchers working in the laboratory of Mohamed Kabbaj, a professor of Biomedical Sciences and Neuroscience in the College of Medicine, showed that ketamine can decrease alcohol consumption in male rats that
Artificial intelligence can be used to predict molecular wave functions and the electronic properties of molecules. This innovative AI method could be used to speed-up the design of drug molecules or new materials.
Scientists have successfully produced human tissues from stem cells. They have a complexity similar to that of normal tissue and are far superior to previous structures.
The biological sensors change color once they have successfully snared a target molecule, and will soon have a host of important environmental, medical and security applications.
15-meter high waves that pushed boulders the weight of a Leopard tank inland: This is more or less how one can imagine the tsunami that hit the coast of today's Sultanate of Oman about 1,000 years ago, as concluded by a recent study. The findings also show how urgently the region needs a well-functioning early warning system.
PLUS. DTU vil udbyde den efteruddannelse, der er behov for – men også i en form, der passer virksomhederne og den enkelte. Det kræver en kulturændring, erkender direktøren for nyt center.
S tephen Miller's liberal critics were right after all. The influential White House aide and immigration hard-liner has long been a liberal target. Prominent conservatives such as the National Review editor Rich Lowry have defended Miller as a "wunderkind" and praised his "knowledge, energy, and doggedness." But liberals have maintained for years that Miller is pushing an agenda far more sinister
Single-wall carbon nanotubes (SWCNT) have found many uses in electronics and new touch screen devices. Carbon nanotubes are sheets of one atom-thick layer of graphene rolled up seamlessly into different sizes and shapes. To be able to use them in commercial products like transparent transistors for phone screens, researchers need to be able to easily test nanotubes for their materials properties,
Everyone knows about Apollo 11, the first moon landing. And about ill-fated Apollo 13. Between them is the forgotten mission — Apollo 12. (Image credit: NASA)
Researchers report that among patients with obesity, robotic kidney transplants produce survival outcomes comparable to those seen among nonobese patients. The study includes data collected over 10 years from more than 230 robotic-assisted kidney transplants in patients with obesity.
A new Yale study shows that some patients being treated for severe heart failure with a battery-operated pump saw significant improvement after additionally using neurohormonal blockade (NHB) drug therapy.
This study examined state laws that grant individuals and institutions rights to refuse participation in abortion based on their beliefs, that grant immunity from liability for such refusals, and that limit conscience rights when patient safety is at risk.
Adults experiencing a migraine of moderate or severe severity took the drug ubrogepant or placebo and reported if after two hours they were free of pain and of their most bothersome migraine-associated symptom in this randomized clinical trial.
A discovery about how the immune system responds to malaria infection could lead to better treatments for hepatitis C, HIV and lupus, say Melbourne researchers. The research team showed, in laboratory models, that strong inflammatory signals caused by malaria infection activate molecules that trigger the production of highly potent antibodies to fight the disease.
This randomized clinical trial compared maternal blood loss with immediate umbilical cord clamping (within 15 seconds after birth) versus delayed clamping (60 seconds after birth) in 113 women who had a scheduled cesarean delivery at term of 37 weeks or more.
Researchers studying six adults who had one of their brain hemispheres removed during childhood to reduce epileptic seizures found that the remaining half of the brain formed unusually strong connections between different functional brain networks, which potentially help the body to function as if the brain were intact. The case study, which investigates brain function in these individuals with he
Milking the umbilical cord — gently squeezing the cord and pushing the contents into the newborn's abdomen before clamping the cord — could increase the risk for severe intraventricular hemorrhage, or bleeding into the brain's fluid-filled cavities, in extremely preterm infants, according to results of a study funded by the National Institutes of Health that was halted for safety concerns.
Neurons that produce the neurotransmitter dopamine communicate with T cells to enhance allergic inflammation in the lungs of young mice but not older mice, researchers report Nov. 19 in the journal Immunity. The findings potentially explain why asthma susceptibility is higher in children. By highlighting the important role of interactions between the nervous system and the immune system in childho
Activation of CD95, a receptor found on all cancer cells, triggers programmed cell death — or does the opposite, namely stimulates cancer cell growth. Scientists from the German Cancer Research Center (DKFZ) have now shown that the impact of CD95 activation depends on whether there are isolated cancer cells or three-dimensional structures. Individual cells are programmed to die following CD95 act
Researchers at Gladstone Institutes are approaching Alzheimer's from a different angle. In a new study published in Cell Reports, they demonstrate that particular patterns of brain activity can predict far in advance whether a young mouse will develop Alzheimer's-like memory deficits in old age.
Coordinated behavior is common in a variety of biological systems, such as insect swarms, fish schools and bacterial colonies. But the way information is spread and decisions are made in such systems is difficult to understand. A group of researchers from Southeast University and China University of Mining and Technology studied the synchronized flight of pigeon flocks. They used this as a basis t
Multiple myeloma is a type of blood cancer in which malignant plasma cells accumulate in the bone marrow, and recent studies have shown that some can leave the marrow and enter the blood stream. Until now, it has been difficult to detect these cells, known as clonal circulating plasma cells, in the blood. In this week's Biomicrofluidics, investigators report development of a new device that can de
Blood clots have long been implicated in heart attacks and strokes. While the role of one key protein, called von Willebrand factor, has been established, a reliable model for predicting how it collects in blood vessels remains elusive. Researchers review recent work on understanding the behavior of vWF in APL Bioengineering, painting a portrait of vWF, and by highlighting advances in the field, t
Embryonic stem cells (ESCs) are distinguished by their dual ability to self-renew and their potential to differentiate, both of which require tight regulatory control. During the differentiation of ESCs, various cells develop into specialised cell types such as skin cells, nerve cells, muscle cells, etc. While our understanding of ES cell regulation has been dominated by transcriptional and epigen
Tracking the lateral position of single cells and particles plays an important role in evaluating the efficiency of microfluidic cell focusing, separation and sorting. Traditionally, the performance of microfluidic cell separation and sorting is evaluated either by analyzing the input and collected output samples requiring multiple steps of off-chip analysis or the use of expensive equipment (e.g.
Trash talking has a long and colorful history of flustering game opponents, and now researchers have demonstrated that discouraging words can be perturbing even when uttered by a robot.
Electricity supply is one of the biggest CO2 emitters globally. To keep global warming well below 2°C, several paths lead to zero emissions in the energy sector, and each has its potential environmental impacts — such as air and water pollution, land-use or water demand. Using a first-time combination of multiple modelling systems, an international team of researchers has now quantified the actua
Embryonic stem cells (ESCs) are distinguished by their dual ability to self-renew and their potential to differentiate, both of which require tight regulatory control. During the differentiation of ESCs, various cells develop into specialised cell types such as skin cells, nerve cells, muscle cells, etc. While our understanding of ES cell regulation has been dominated by transcriptional and epigen
In the deep sea, far away from the light of the sun, organisms use chemical energy to fix carbon. At hydrothermal vents—where hot, mineral-rich water gushes out of towering chimneys called black smokers—vibrant ecosystems are fueled by chemical energy in the vent waters. Mussels thrive in this seemingly hostile environment, nourished by symbiotic bacteria inside their gills. The bacteria convert c
Researchers at the National Institute of Standards and Technology (NIST) have made one of the highest-performance cameras ever composed of sensors that count single photons, or particles of light.
It's the latest trend in the world's tech capital. But is it really possible to cut yourself off from everything in life that excites you – and can it be any good for you? They have done biohacking , clean sleeping and the keto diet , but now Silicon Valley types have coined a new health trend – dopamine fasting. It is thought that depriving yourself of the neurotransmitter, a chemical messenger
In the deep sea, far away from the light of the sun, organisms use chemical energy to fix carbon. At hydrothermal vents—where hot, mineral-rich water gushes out of towering chimneys called black smokers—vibrant ecosystems are fueled by chemical energy in the vent waters. Mussels thrive in this seemingly hostile environment, nourished by symbiotic bacteria inside their gills. The bacteria convert c
Researchers from McMaster University have discovered striking variation in the underlying genetic machinery that orchestrates sexual differentiation in frogs, demonstrating that evolution of this crucial biological system has moved at a dramatic pace.
Researchers at Tohoku University have, for the first time, successfully demonstrated a formation and current-induced motion of synthetic antiferromagnetic magnetic skyrmions. The findings are expected to pave the way towards new functional information processing and storage technologies.
The South Pole-Aitken (SPA) is the largest and deepest basin on the Moon, theoretically opening a window into the lunar lower crust and likely into the upper mantle. However, compositional information of the SPA basin was mainly obtained from orbital remote sensing. Chang'E-4 landed in the SPA Basin, providing a unique chance for in situ probing the composition of the lunar interior. The landing s
Don't take toilets for granted. Their connection to a managed sewage disposal system protects you from diseases and infections that can stunt your growth, harm your nutrition and even kill you.
Researchers from McMaster University have discovered striking variation in the underlying genetic machinery that orchestrates sexual differentiation in frogs, demonstrating that evolution of this crucial biological system has moved at a dramatic pace.
Fifteen-meter high waves that pushed boulders the weight of a Leopard tank inland: This is more or less how one can imagine the tsunami that hit the coast of today's Sultanate of Oman about 1,000 years ago, as concluded by a recent study by the universities of Bonn, Jena, Freiburg and RWTH Aachen. The findings also show how urgently the region needs a well-functioning early warning system. But eve
Infectious diseases are caused by pathogenic microorganisms capable of entering, colonizing and growing within a host organism, thus producing an infection. Bacterial infections have been on the rise worldwide in recent years, but many mechanisms underlying bacterial pathogenesis are still poorly understood. This is highly relevant given the fact that the development of new antimicrobial therapies
A recent "deep learning" algorithm—despite having no innate knowledge of solar physics—could provide more accurate predictions of how the sun affects our planet than current models based on scientific understanding.
Blood clots have long been implicated in heart attacks and strokes, together accounting for almost half of deaths annually in the United States. While the role of one key protein in the process, called von Willebrand factor, has been established, a reliable model for predicting how vWF collects in blood vessels remains elusive.
Coordinated behavior is common in a variety of biological systems, such as insect swarms, fish schools and bacterial colonies. But the way information is spread and decisions are made in such systems is difficult to understand.
Multiple myeloma is a type of blood cancer in which malignant plasma cells, a type of white blood cell, accumulate in the bone marrow. This leads to bone destruction and failure of the marrow, which in healthy individuals, produce all the body's red blood cells. The most recent data from the American Cancer Society estimates that almost 27,000 new cases of MM are diagnosed every year, and of these
Killer cells of the immune system detect and kill infected cells or cancer cells. Researchers at the Institute of Pathology at the University of Bern have now discovered that the mechanism by which certain immune cells kill their target cells can also be used to control the killer cells themselves. This finding may be relevant to cancer immunotherapy.
Using a chemical compound called YKL-05-099, a team of cancer researchers from CSHL and the Dana Farber Institute was able to target the Salt-Inducible Kinase 3 (SIK3) pathway and extend survival in mice with MLL leukemia.
The leftovers from a spectacular supernova that revolutionized our understanding of how stars end their lives have finally been spotted by astronomers at Cardiff University.
Silicon integrated circuits, which are used in computer processors, are approaching the maximum feasible density of transistors on a single chip — at least, in two-dimensional arrays.
Yoga and physical therapy (PT) are effective approaches to treating co-occurring sleep disturbance and back pain while reducing the need for medication, according to a new study from Boston Medical Center. Published in the Journal of General Internal Medicine, the research showed significant improvements in sleep quality lasting 52 weeks after 12 weeks of yoga classes or 1-on-1 PT, which suggests
Nature, Published online: 19 November 2019; doi:10.1038/d41586-019-03521-4 Draft genomes of more than 800 species hint at the role of interbreeding in the animal's evolution.
Nature, Published online: 19 November 2019; doi:10.1038/d41586-019-03524-1 The state's universities can help to design and build a clean and resilient power grid.
Multiple myeloma is a type of blood cancer in which malignant plasma cells, a type of white blood cell, accumulate in the bone marrow. This leads to bone destruction and failure of the marrow, which in healthy individuals, produce all the body's red blood cells. The most recent data from the American Cancer Society estimates that almost 27,000 new cases of MM are diagnosed every year, and of these
Why do we make poor decisions that we know are bad for our health? In this frank, funny talk, behavioral economist and health policy expert David Asch explains why our behavior is often irrational — in highly predictable ways — and shows how we can harness this irrationality to make better decisions and improve our health care system overall.
Infectious diseases are caused by pathogenic microorganisms capable of entering, colonizing and growing within a host organism, thus producing an infection. Bacterial infections have been on the rise worldwide in recent years, but many mechanisms underlying bacterial pathogenesis are still poorly understood. This is highly relevant given the fact that the development of new antimicrobial therapies
Galaxy clusters have been fascinating astronomers for decades. Often consisting of thousands of galaxies, the clusters are the largest known structures being held together by gravitational forces. At their centers, astronomers have found some of the biggest and most powerful black holes ever discovered, and high-energy jets of extremely hot particles emanating from these black holes were found to
A small, private higher-education institution in Massachusetts long known as Lasell College recently underwent a subtle but significant transformation: It changed its name. Now the school goes by Lasell University . Its longtime president, Michael B. Alexander, described the new name as "aspirational." He thinks it better reflects the breadth of the school's offerings, and hopes the university de
In a boon to wind farms, average daily wind speeds are picking up across much of the globe after about 30 years of gradual slowing. Research shows that wind speeds in northern mid-latitude regions have increased by roughly 7% since 2010.
Watch out for 'feather duvet lung' doctors have warned after treating a middle aged man with severe lung inflammation that developed soon after he bought feather-filled bedding.
A new screening system developed by scientists leverages redundancy in an important component of a cell – nucleotide metabolism – to help identify new drugs that specifically and potently block processes that are essential for cancer cell growth.
If people are educated on recycled water, they may come to agree it's perfectly safe and tastes as good — or better — than their drinking water. They may even agree it's an answer to the critical water imbalance in California. But that doesn't mean they're going to use recycled water — and it sure doesn't mean they'll drink it. And the reason lies in the word 'disgust.'
Biologists have succeeded in cultivating several dozen marine bacteria in the laboratory — bacteria that had previously been paid little attention. The researchers then carried out a functional characterization of the bacteria, thus enabling a systematic screening for active substances. Initial bioinformatic analyses and cell biological observations indicate potential for the production of new an
Like cosmic hard drives, black holes pack troves of data into compact spaces. But ever since Stephen Hawking calculated in 1974 that these dense spheres of extreme gravity give off heat and fade away, the fate of their stored information has haunted physicists. The problem is this: The laws of quantum mechanics insist that information about the past is never lost, including the record of whatever
Researchers from McMaster University have discovered striking variation in the underlying genetic machinery that orchestrates sexual differentiation in frogs, demonstrating that evolution of this crucial biological system has moved at a dramatic pace.
The biological sensors change color once they have successfully snared a target molecule, and will soon have a host of important environmental, medical and security applications.
A team of scientists from the Universitat Autonoma de Barcelona and the Centre de Regulació Genomica have created the BacFITBase database, which characterises bacterial genes relevant to the infection process in live organisms. The new database will make it easier to identify new therapeutic targets for the creation of antibiotics.
Artificial intelligence can be used to predict molecular wave functions and the electronic properties of molecules. This innovative AI method developed by a team of researchers at the University of Warwick, the Technical University of Berlin and the University of Luxembourg, could be used to speed-up the design of drug molecules or new materials.
Nuclear RNA levels are kept in check by RNA decay factors. Now, researchers at Aarhus and Copenhagen Universities show that an excess of RNA in the nucleus can have negative effects on a crucial regulator of stem cell differentiation.
New research digs into the factors that trigger moms with substance use disorders to parent their children harshly. As the researchers define it, harsh parenting can include nonverbal communication, such as angry or contemptuous facial expressions and menacing or threatening body postures; emotional expression, such as irritability, lack of patience and sensitivity, sarcastic comments, and curt a
Engineers can now efficiently convert heat into electricity, creating a huge potential to reduce greenhouse effects by capturing exhaust heat and cutting down primary energy wastage.
Semiconductors convert energy from photons into an electron current. However, some photons carry too much energy for the material to absorb. These photons produce 'hot electrons', and the excess energy of these electrons is converted into heat. Materials scientists have been looking for ways to harvest this excess energy. Scientists have now shown that this may be easier than expected.
After the Rio Earth Summit in 1992, world leaders committed to pursue a sustainable development agenda. This commitment has resulted in tens of billions of dollars invested in forest conservation to mitigate climate change. But do these financial incentives work? A new study says, yes, but only if payments continue.
In order to orient ourselves in space, and to find our way around, we form mental maps of our surroundings. But what happens if the coordinate system of our brain, which measures our mental maps, is distorted?
Exercise referral schemes are associated with many improvements in health and wellbeing, but the changes aren't as large as hoped, finds an analysis of outcomes data.
Over 6 years, researchers evaluated the cognitive effects of statins in elderly consumers, revealing no negative impact and potential protective effects in those at risk of dementia.
A researcher encountered a colorful creature called a disco clam in an Indonesian reef. Now, recent research suggests that she may be narrowing in on answering why this bivalve looks so wild.
Every drop of fresh water contains thousands of different organic molecules that have previously gone unnoticed. By measuring the diversity of these molecules and how they interact with the environment around them, research has revealed an invisible world that affects the functioning of freshwater ecosystems and can contribute to greenhouse gas emissions.
The Chandra X-Ray Observatory was the heaviest payload to be carried into space by a shuttle. It's been looking at supernovas, black holes and spiral galaxies for two decades. Observatory director Belinda Wilkes gives you a tour of Chandra's universe. From: Scientific American
CONCORD, N.H.—"We! Will! Rise!" Cory Booker's supporters chanted as he made his way down the hallway of the New Hampshire statehouse to file for the primary on Friday morning. "We will rise," Booker wrote on a copy of the primary-ballot announcement that the secretary of state had, for commemorative purposes, asked all the candidates to sign. Booker had a hard time squeezing his words in, because
While gaming GPUs get most of the attention, workstation graphics cards are essential for many kinds of engineering, scientific, AI, and multimedia tasks. So I was eager to get a chance to test out a pre-release version of AMD's new Radeon Pro W5700 workstation GPU ($799). Radeon Pro W5700 By the Numbers First, it was a relief to get a new GPU that sticks to a similar power envelope to prior vers
New research clarifies how one generation transmits mitochondrial DNA, and potentially mitochondrial disease, to the next. The study finds that children born to older mothers carry more mitochondrial mutations than do children born to younger mothers, which could have important implications for the inheritance of disease-related mutations. Mitochondria are cellular subunits that produce energy, a
Vi måste flyga mindre. Skogen, ängarna och städerna kan komma att se lite annorlunda ut. Men i det stora hela blir livet i det fossilfria Sverige ungefär som idag. Och kostnaderna för själva omställningen – den är marginell, menar forskarna. – I stora drag är de tekniska lösningarna redan på gång, även om det återstår att införa dem i full skala. Det svåra är beteendefrågor och att hitta rätt sty
Den rullar in på lagret och scannar av sin omgivning. Den autonoma lagerroboten planerar sitt arbete och är redo att packa och lasta varor på lastpallar – allt i samspel med människor och andra robotar. Forskare vid Örebro universitet testar nu sin robot skarpt. I tre års tid har Örebroforskare inom ramen för EU-projektet Iliad arbetat med att utveckla autonoma lagerrobotar som kan arbeta med män
Special light beams can be used to manipulate molecules or small biological particles. However, these optical tweezers only work with objects in empty space. Any disturbing environment would deflect the light waves and destroy the effect. This is a problem, in particular with biological samples. Now, a special method was developed to calculate the perfect wave form to manipulate small particles in
Scientists at the University of Würzburg have successfully produced human tissues from stem cells. They have a complexity similar to that of normal tissue and are far superior to previous structures.
There has been a substantial increase in food production over the last 50 years, but it has been accompanied by a narrowing in the diversity of cultivated crops. New research shows that diversifying crop production can make food supply more nutritious, reduce resource demand and greenhouse gas emissions, and enhance climate resilience without reducing calorie production or requiring more land.
By understanding how, when, and why badgers move from one social group to another, researchers hope information gleaned from GPS devices will help them tailor vaccination programs to reduce the spread of bovine tuberculosis.
15-meter high waves that pushed boulders the weight of a Leopard tank inland: This is more or less how one can imagine the tsunami that hit the coast of today's Sultanate of Oman about 1,000 years ago, as concluded by a recent study by the universities of Bonn, Jena, Freiburg and RWTH Aachen. The findings also show how urgently the region needs a well-functioning early warning system.
Scientists at Aalto University, Finland, and Nagoya University, Japan, have found a new way to make ultra-clean carbon nanotube transistors with superior semiconducting properties.
Chang'E-4 research team lead by Prof. Yangting Lin from Key Laboratory of Earth and Planetary Physics, Institute of Geology and Geophysics, Chinese Academy of Sciences, suggested that olivine-norite rock detected by the lunar rover Yutu-2 likely crystallized from the SPA impact melt pool. This work is published in National Science Review.
A recent paper from the lab of Professor Sudhir Krishna at the National Centre for Biological Sciences, Bangalore, reviews the progress made in cervical cancer research over the past 25 years. This extensive coverage published in the journal of Experimental Cell Research highlights the role of a popular signaling molecule called Notch in human cervical cancer progression.
Presented in a study published in the journal Medical Image Analysis by Mariana Nogueira and Mathieu De Craene, first authors, within the framework of the CardioFunxion project, led by Bart Bijnens (ICREA) and Gemma Piella, members of the Physense and SiMBioSys research groups at BCN MedTech, experts in Machine Learning for clinical decision-making.
SUTD researchers developed an N-shaped electrode-based microfluidic impedance cytometry device for the simultaneous measurement of the lateral position and physical properties of single cells and particles in continuous flows. This novel microdevice can be easily integrated with other microfluidic platforms as a downstream approach for the real-time characterization of the sorting efficiency and b
A new group of symbiotic bacteria in deep-sea mussels surprises with the way they fix carbon: They use the Calvin cycle to turn carbon into tasty food. The bacteria acquired the genes for this process from neighboring symbiotic bacteria in the mussel. These results from a recent study by scientists from the Max Planck Institute for Marine Microbiology, now published in ISME Journal, call into ques
Researchers at the National Institute of Standards and Technology (NIST) have made one of the highest-performance cameras ever composed of sensors that count single photons, or particles of light.
While exercise offers benefits for a wide range of health conditions, it has historically been considered too dangerous for people living with sickle cell disease (SCD). However, a new study published today in the journal Blood adds to mounting evidence that low- to moderate-intensity exercise may be not only safe, but beneficial for these patients.
PLUS. I 2019 indsættes første Airbus A321LR, som kan flytte 157 passagerer op til 6.700 kilometer. Det er nok til at nå til Alaska, Congo, Oman, Nepal og Mongoliet.
A team of researchers from the University of North Carolina at Charlotte and Universidad Técnica de Manabí in Ecuador has found and reported on ancient infant skulls that were excavated at a site in Salango, Ecuador. In their paper published in the journal Latin American Antiquity, the group describes how the infant skulls were encased in the skulls of older children.
With the polarization of America's media and politics reaching a fever pitch, many news consumers—"worn out by a fog of political news," as a recent New York Times feature put it – are responding by tuning out altogether.
Managing reservoirs for water quality, not just flood control, could be part of the solution to the growth of toxic algal blooms in the Great Lakes, especially Lake Erie, every summer.
Nature, Published online: 19 November 2019; doi:10.1038/d41586-019-03529-w Some researchers have their manuscripts screened for errors before they go to journals.
Months after being fitted with a bionic eye — a camera hooked up to a neural implant — a man named Jason Esterhuizen was able to see for the first time since he was blinded by a car accident. Esterhuizen is one of six people in the world to be outfitted with the Orion , an experimental device that takes video footage, converts it into electrical activity, and stimulates the pattern onto the visua
Our personalities impact almost everything we do, from the career path we choose to the way we interact with others to how we spend our free time. But what about the way we drive—could personality be used to predict whether a driver will cut someone off, speed, or, say, zoom through a yellow light instead of braking? There must be something to the idea that those of us who are more mild-mannered
An international team of researchers has found that people in space for long durations can experience blood flowing in the wrong direction in the jugular vein. In their paper published on JAMA Network Open, the group describes their study of blood flow in astronauts.
Nanooptical traps are a promising building block for quantum technologies. Austrian and German scientists have now removed an important obstacle to their practical use. They were able to show that a special form of mechanical vibration heats trapped particles in a very short time and knocks them out of the trap.
Researchers from the Universities of Granada and Zaragoza and the Edinburgh Cancer Research Center have developed a new tool in the fight against cancer. Their study, recently published in the prestigious journal Nature Catalysis, delivers palladium catalysts directly into cancer cells inside tiny vesicles (exosomes) to activate the chemotherapeutic drug in situ.
Malicious third-party advertisers or hackers expose web users to a security threat by injecting malicious JavaScript code to intercept user clicks and trick them into visiting untrusted web content.
Researchers at Tohoku University have, for the first time, successfully demonstrated a formation and current-induced motion of synthetic antiferromagnetic magnetic skyrmions. The established findings are expected to pave the way towards new functional information processing and storage technologies.
Genetic analyses have revealed remarkably higher species diversity in common red seaweed than previously assumed. It was thought that there were only five related species of the Gloiopeltis genus worldwide. However, it has been revealed that there are over ten in Japan alone. The reinstatement of the species Gloiopeltis compressa (Ryukyu-funori) was proposed by this international research collabor
A NASA study reveals new dangers to the human body in space. The absence of gravity caused changes in people's blood flows. Some had blood going in reverse while others developed clots. None Humanity's expansion into space is both a hopeful and risky endeavor. A new study from NASA identified a new danger – low gravity can make blood flow stop and actually go in reverse in some astronauts. The co
An international team of researchers has found what appears to be one of the secrets to evolutionary success for beetles—genes stolen from bacteria and fungi. In their paper published in Proceedings of the National Academy of Sciences, the group describes their study of the beetle genome and what they found.
The predentary bone is one of the most enigmatic skeletal elements in avian evolution. Located at the tip of the lower jaw, this bone is absent in more primitive birds and in living birds; it is thought to have been lost during evolution. For over 30 years, the origin and function of the avian predentary has remained mysterious.
A small, motorized fishing boat heads out to sea from the port of Sinabang, leaving behind the remote island of Simeulue, off the coast of western Sumatra. Noticeable on the deck is a tangle of plastic tubes, linked up to a roaring, spluttering engine. The on-board fishers are going "compressor fishing," a practice that involves divers searching the seabed for lucrative octopus, grouper and sea cu
An international team of researchers has found what appears to be one of the secrets to evolutionary success for beetles—genes stolen from bacteria and fungi. In their paper published in Proceedings of the National Academy of Sciences, the group describes their study of the beetle genome and what they found.
While counterintuitive, engaging in competition with family and friends decreases the odds of long-term use of activity trackers among older adults, perhaps because they feel it's demotivating, according to a new study. Wanting to lose weight, become more active, and monitor health doesn't seem to influence length of use either, the study finds. But tech savvy does. "For older adults, motivation
A small, motorized fishing boat heads out to sea from the port of Sinabang, leaving behind the remote island of Simeulue, off the coast of western Sumatra. Noticeable on the deck is a tangle of plastic tubes, linked up to a roaring, spluttering engine. The on-board fishers are going "compressor fishing," a practice that involves divers searching the seabed for lucrative octopus, grouper and sea cu
A strong economic recovery over the past decade has saved many jobs and slowed automation in the United States, but a new report says less-educated, younger and minority workers in the Midwest manufacturing industry are being displaced at the highest rates by robots.
New research from The Australian National University (ANU) has found overconfidence driven by outstanding performance is the decisive factor when companies behave badly.
Using drones deployed in the air and GoPros underwater, Oregon State University marine ecologist Leigh Torres recently completed her fourth field season documenting previously unseen behaviors of gray whales—and gathering their poop—off the Oregon coast.
Using drones deployed in the air and GoPros underwater, Oregon State University marine ecologist Leigh Torres recently completed her fourth field season documenting previously unseen behaviors of gray whales—and gathering their poop—off the Oregon coast.
Lakes and ponds are the final resting place for many of the Earth's plants. Rivers collect much of the planet's dead organic matter, transporting it to rest in calmer waters.
To synthesize high-performance materials for organic photovoltaics (OPVs) that convert solar radiation into direct current, materials scientists must meaningfully establish the relationship between chemical structures and their photovoltaic properties. In a new study on Science Advances, Wenbo Sun and a team including researchers from the School of Energy and Power Engineering, School of Automatio
Nature, Published online: 19 November 2019; doi:10.1038/d41586-019-03505-4 How Nature reported the hatching of a penguin chick at Edinburgh Zoo in 1919, and a golden age for astrophysics in the 1960s.
Forty years ago, a Voyager spacecraft snapped the first closeup images of Europa, one of Jupiter's 79 moons. These revealed brownish cracks slicing the moon's icy surface, which give Europa the look of a veiny eyeball. Missions to the outer solar system in the decades since have amassed enough additional information about Europa to make it a high-priority target of investigation in NASA's search f
A review of the iconic Atlantic goliath grouper by a team of Florida State University scientists revealed considerable downsides to proposals to reopen the fishery that has been closed for nearly 30 years.
The two robots each work on their own side of the jet. (Alex Lloyd / US Air Force/) Most of the Air Force's F-16 fleet is painted a shade of grey. In addition to their camouflage effect, the top coats and primer below them prevent the pricy metal planes from corrosion due to moisture. Just like a house needs to be repainted from time to time, so do fighter jets. Sometimes, a maintenance crew can
Close Encounters Neptune has 14 confirmed moons , one of which is so far away from the planet that it needs 27 Earth years to complete a single orbit. But the two closest moons, Naiad and Thalassa, whip around the ice giant every seven and seven-and-a-half hours, respectively — and engage in a strange "dance," according to new research, in order to avoid slamming into one another along their brie
A review of the iconic Atlantic goliath grouper by a team of Florida State University scientists revealed considerable downsides to proposals to reopen the fishery that has been closed for nearly 30 years.
As blue-green algae proliferates around the world, a University of Saskatchewan (USask) researcher cautions that current municipal drinking water monitoring that focuses on a single toxin associated with the cyanobacteria blooms is likely to miss the true public health risks.
Two common species of small mammals are not significantly disturbed by industrial activity near their homes, according to a new study by University of Alberta scientists.
As blue-green algae proliferates around the world, a University of Saskatchewan (USask) researcher cautions that current municipal drinking water monitoring that focuses on a single toxin associated with the cyanobacteria blooms is likely to miss the true public health risks.
Two common species of small mammals are not significantly disturbed by industrial activity near their homes, according to a new study by University of Alberta scientists.
Iridium is an ideal catalyst for the electrolytic production of hydrogen from water—but it is extremely expensive. But now a new kind of electrode made of highly porous material does an excellent job with just a hint of iridium.
Med den kommende finanslov er der lagt op til, at Innovationsfonden får øremærket 800 millioner kroner til grønne udviklingsprojekter. Fondens klimapanel har derfor kastet lys over, hvilke klimaløsninger Danmark får mest ud af at investere i.
The UK Office for National Statistics says men aged 70 feel as healthy as 65-year-old men did in 1997. Women aged 70 feel as healthy as 65-year-olds did in 1981
Nitrous oxide (N2O) (more commonly known as laughing gas) is a powerful contributor to global warming. It is 265 times more effective at trapping heat in the atmosphere than carbon dioxide and depletes our ozone layer.
Vindkraften har fått medvind. Sedan år 2010 har den globala genomsnittliga vindhastigheten ökat och därmed också tillgången på energi för vindkraftsindustrin. Det visar en internationell forskarstudie. Sedan länge har det för forskarna varit känt att vindhastigheterna på land minskat från och med 1980-talet. Samtidigt har den globala uppvärmningen ökat. – Genom global uppvärmning så minskar tempe
Stor variation i generna är bra för överlevnaden hos arter som förökar sig sexuellt. Nu visar forskare från Uppsala universitet att det är en genetisk dragkamp mellan könen som upprätthåller variationen. Hos arter med sexuell fortplantning finns inte två individer som är exakt lika och forskare har länge kämpat med att förstå varför det finns så mycket genetisk variation. För viktiga egenskaper s
Two-thirds of the childhood sexual-abuse survivors met the criteria for complete mental health, this study found. Greater understanding of factors associated with complete mental health among survivors is an important first step in helping survivors achieve the level of well-being found in the general adult population.
Complications following a procedure to treat tongue-tie in babies are occurring that can result in admission to hospital, something a University of Otago paediatrician says needs to be better understood by both health practitioners and parents.
Rates of new anal cancer diagnoses and deaths related to human papillomavirus (HPV), the most common sexually transmitted infection, have increased dramatically over the last 15 years, according to researchers at The University of Texas Health Science Center at Houston (UTHealth). The results of their study were published in the November issue of the Journal of the National Cancer Institute.
Some continuous glucose monitoring (CGM) alarm features and settings may achieve better blood sugar control for people with type 1 diabetes, according to a study published in the Journal of the Endocrine Society.
University of Adelaide wine researchers say their latest discovery may one day lead to winemakers being able to manipulate the acidity of wines without the costly addition of tartaric acid.
UNSW Sydney researchers have successfully merged 3D/4D printing with a chemical process to produce 'living' resin, which has huge potential for fields as diverse as recycling and biomedicine.
Jupiter is the largest planet in the solar system. In terms of mass, Jupiter dwarfs the other planets. If you were to gather all the other planets together into a single mass, Jupiter would still be 2.5 times more massive. It is hard to understate just how huge Jupiter is. But as we've discovered thousands of exoplanets in recent decades, it raises an interesting question about how Jupiter compare
With increased efforts to create a more dynamic power grid that is cleaner, more reliable and more efficient, utilities are tapping into various new technologies and programs. A popular energy solution is demand response (DR). Typically implemented in the industrial sector where energy use is high and peak energy demand comes at a significant cost to utilities and the grid itself, DR usage is gain
China Number One In 2018, China completed more successful orbital launches than any other nation for the first time, with its 35 flights dwarfing the United States' 29 launches and Russia's 20. Now, Ars Technica reports that the country is on pace to set the record again this year — yet another sign that China is largely shaping the future of space exploration despite U.S. companies like SpaceX d
For older adults, wearable activity trackers may be popular gifts, but they may not be used for very long. While counterintuitive, engaging in competition with family and friends decreases the odds of long-term use among older adults, perhaps because they feel it's demotivating, according to a new study.
Artificial light at night negatively impacts thousands of species: beetles, moths, wasps and other insects that have evolved to use light levels as cues for courtship, foraging and navigation. Scientists reviewed 229 studies to document the myriad ways that light alters the living environment such that insects are unable to carry out crucial biological functions.
Scientists leveraged LISA Pathfinder's record-setting sensitivity (designed to ripples in space-time produced by, among other things, merging black holes) for a different purpose much closer to home — mapping microscopic dust shed by comets and asteroids.
A new study from an international group of scientists finds we are releasing more of the greenhouse gas nitrous oxide into the atmosphere than previously thought.
This is not going to be a reassuring story – not for the biomedical literature, and not for the Chinese scientific establishment. But the head of the official Research Integrity initiative there, Xuetao Cao, a former head of the Chinese Academy of Medical Sciences and current president of Nankai University, is now thoroughly involved in a faked-research scandal of his own. Here's a post from Leon
Nanooptical traps are a promising building block for quantum technologies. Austrian and German scientists have now removed an important obstacle to their practical use. They were able to show that a special form of mechanical vibration heats trapped particles in a very short time and knocks them out of the trap.
Styrelsen forklarer og forsvarer sig, mens lægerne bl.a. opfordrer styrelsen til at fokusere mere på læring. Det er vanskeligt at se, hvordan denne form for debat kan fremmane kvalificerede løsninger, skriver professor Mette Hartlev.
Genetic analyses have revealed remarkably higher species diversity in common red seaweed than previously assumed. It was thought that there were only five related species of the Gloiopeltis genus (known as 'funori' in Japanese) worldwide. However, genetic analyses of historic and modern specimens have revealed that there are over ten in Japan alone. The reinstatement of the species Gloiopeltis com
Genetic analyses have revealed remarkably higher species diversity in common red seaweed than previously assumed. It was thought that there were only five related species of the Gloiopeltis genus (known as 'funori' in Japanese) worldwide. However, genetic analyses of historic and modern specimens have revealed that there are over ten in Japan alone. The reinstatement of the species Gloiopeltis com
Down syndrome, due to an extra chromosome 21, occurs in 250,000 children and adults in the United States, making it the country's most common chromosomal disorder. Inherited heart defects, thyroid cancer, celiac disease and developmental disabilities are common Down syndrome complications. Only recently has catatonia, a behavioral condition marked by new onset immobility, mutism, withdrawal and ot
Professor Kaoru Minoshima from the University of Electro-Communications and NEOARK Corporation have succeeded in prototyping a greatly improved magneto-optic effect measurement device as part of the ERATO MINOSHIMIA Intelligent Optical Synthesizer Project, under the JST Strategic Basic Research Programs. An exhibition of the prototype device is planned for the Science Photonics Fair 2019 being hel
University of Adelaide wine researchers say their latest discovery may one day lead to winemakers being able to manipulate the acidity of wines without the costly addition of tartaric acid.
Simply planting a hedge in front of a park can halve the amount of traffic pollution that reaches children as they play, finds a new study by the University of Surrey.
Metal nanoclusters that bear tunable surface ligands could help develop next-generation imaging and photocatalytic approaches, suggests work by KAUST researchers.
University of Adelaide wine researchers say their latest discovery may one day lead to winemakers being able to manipulate the acidity of wines without the costly addition of tartaric acid.
Mitochondria, often thought of as the powerhouses of cells, are just one part of a larger living thing, but they are unique among cellular structures in that they have their own DNA that is distinct from that of their parent cells. And just like their parent cells, mitochondria need quality-control mechanisms to maintain their DNA and preserve their normal function.
Lamprey are blood-sucking vampire-like fish that attach to and eventually kill game fish, making them the bane of many a fisherman's existence. Like something out of a horror film, these parasites use radial rows of sharp teeth to dig into the skin of their host and extract blood and other fluids for food. But to Caltech scientists, these gruesome pests hold important clues to the evolution and su
Want your pipes fixed? Call a plumber. Need an illness diagnosed? See a doctor. Looking to boost your country's economy? Choose a leader who was educated in economics.
Using the Cooled Mid-Infrared Camera and Spectrometer (COMICS) on the Subaru Telescope, astronomers have detected an unidentified infrared emission band from comet 21P/Giacobini-Zinner (hereafter, comet 21P/G-Z) in addition to the thermal emissions from silicate and carbon grains. These unidentified infrared emissions are likely due to complex organic molecules, both aliphatic and aromatic hydroca
Mitochondria, often thought of as the powerhouses of cells, are just one part of a larger living thing, but they are unique among cellular structures in that they have their own DNA that is distinct from that of their parent cells. And just like their parent cells, mitochondria need quality-control mechanisms to maintain their DNA and preserve their normal function.
Lamprey are blood-sucking vampire-like fish that attach to and eventually kill game fish, making them the bane of many a fisherman's existence. Like something out of a horror film, these parasites use radial rows of sharp teeth to dig into the skin of their host and extract blood and other fluids for food. But to Caltech scientists, these gruesome pests hold important clues to the evolution and su
Undervisningen av skönlitteratur på svenska gymnasieskolor är instrumentell och styrs ofta av lärarnas behov av att kunna kontrollera eleverna. Det visar en studie från Umeå universitet, som undersöker gymnasielärares syn på litteraturundervisning inom svenskämnet. Språkutveckling anges som ett vanligt skäl till att läsa skönlitteratur, liksom möjligheten att genom läsningen skapa sammanhang och
Are you excited about the massive research integrity hypocrisy around China's first immunologist Xuetao Cao? Smut Clyde will explain to you the Flaw Cytometry and other naughtiness they uncovered, led by Elisabeth Bik.
Using advanced metagenomics techniques, researchers have found that conventional culture-based lab tests may misdiagnose as many as half of the microbial causes of diarrheal diseases in children. The study, based on samples from Ecuadorian children, also found that a common strain of the E. coli bacterium may be more virulent than previously believed.
India is the No. 1 cotton producer in the world, but its crop is in distress. Heavy use of pesticides, new genetically modified seeds, suicides, and an overabundance of seed choices have interacted within the past decade to create an environment for farmers that is dangerous and potentially even fatal.
Using advanced metagenomics techniques, researchers have found that conventional culture-based lab tests may misdiagnose as many as half of the microbial causes of diarrheal diseases in children. The study, based on samples from Ecuadorian children, also found that a common strain of the E. coli bacterium may be more virulent than previously believed.
Repairing and reusing plastics and delivering cancer drugs more effectively are only two of many of the potential applications a new 3-D/4-D printing technology might have, thanks to the pioneering work of a research collaboration between UNSW Sydney and The University of Auckland.
Concrete is the most widely used man-made material, commonly used in buildings, roads, bridges and industrial plants. But producing the Portland cement needed to make concrete accounts for 5-8% of all global greenhouse emissions. There is a more environmentally friendly cement known as MOC (magnesium oxychloride cement), but its poor water resistance has limited its use—until now. We have develope
Despite mounting attention to the threat of "fake news" on the internet and efforts nationwide to improve digital media literacy, high school students still have difficulty discerning fact from fiction online, according to new research from scholars at Stanford Graduate School of Education.
Intermittent exposure to high levels of alcohol in adolescent animals leads to increased levels of microRNA-137 in the brains of adults. Blocking microRNA-137 helps to reverse or the lasting effects of youth drinking, such as increased alcohol use and anxiety.
Young people who attend diverse schools are more likely later in life to befriend or date people of a different race, according to a new book. In studying the forces that divide Americans along racial lines, Grace Kao, professor of sociology and chair of the sociology department at Yale University, examines two universal desires that bind us—friendship and romance. Her new book, The Company We Ke
Supermassive black holes, weighing millions or even billions of times our Sun's mass, are still only a tiny fraction of the mass of the galaxies they inhabit. But in some cases, the central black hole is the tail wagging the dog. It seems that black holes can run hot or cold when it comes to either enhancing or squelching star birth inside a cluster of galaxies.
Lægeformand Andreas Rudkjøbing ryster på hovedet over Vangsted udmelding om, at lægeformanden skulle skabe unødig frygt for tilsynet. En tilsynssag er både alvorlig og indgribende, skriver han.
Indian Ocean dipole events, linked to bushfires and floods, are becoming stronger and more frequent, scientists say Global heating is "supercharging" an increasingly dangerous climate mechanism in the Indian Ocean that has played a role in disasters this year including bushfires in Australia and floods in Africa. Scientists and humanitarian officials say this year's record Indian Ocean dipole , a
Intel made some significant announcements at Supercomputing 19 on Sunday, including new details on its Xe GPU architecture and a programming model it calls oneAPI. Both products are critical to the company's future plans; Xe represents Intel's first-ever push into data center GPUs and its first discrete GPU in nearly a decade. OneAPI is part of Intel's effort to expand both its total addressable
Bill Ford Jr., right, at media scrum. Can this be more than the merest of coincidences? (Probably. Yeah.) Ford held its biggest car introduction of 2019 Sunday night: the unveiling of the Mustang Mach-E battery-electric SUV. Hundreds of media, analysts and bloggers gathered to see the car firsthand and hear Ford's logic in transplanting the name from one of America's most iconic sports cars and e
In species with sexual reproduction, no two individuals are alike and scientists have long struggled to understand why there is so much genetic variation. A new study shows that a genetic tug-of-war between the sexes acts to maintain variation.
Researchers have demonstrated that an imbalance in the gut microbiota, also known as 'dysbiosis', promotes the onset of colorectal cancer. The teams demonstrated that transplanting fecal flora from patients with colon cancer into mice caused lesions and epigenetic changes characteristic of the development of a malignant tumor. The pilot study led to the development of a non-invasive blood test whi
Synthetic protocells can be made to move toward and away from chemical signals, an important step for the development of new drug-delivery systems that could target specific locations in the body.
Researchers have developed a method that dramatically reduces the amount of water needed to flush a conventional toilet, which usually requires 6 liters.
Ret til få købt sit hus, årlige betalinger, forbedret kompensation for tab af ejendomsværdi og kontant betaling til kommuner, hvor der opstilles vindmøller og solcelleanlæg, skal gøre det lettere at få opstillet vindmøller, solceller og andre grønne energianlæg.
Face blindness often becomes apparent in early childhood, but people occasionally acquire it from a brain injury later in life. A new study of people who became face-blind after a stroke, led by Alexander Cohen, MD, PhD, of Boston Children's Hospital, provides clues to what goes wrong in the brain.
Newly diagnosed prostate cancer patients have multiple standard-of-care treatment options available, but many are not fully informed of their choices. A study led by researchers at The University of Texas MD Anderson Cancer Center found men who seek treatment at a multidisciplinary (MultiD) prostate cancer clinic are more likely to be advised about treatment choices and to receive care that compli
There's new hope that we aren't alone in the universe, that advanced beings may exist on exoplanets. But they're probably not close by, says a new study on the stability of planetary tilts — and orbits — needed to encourage the evolution of complex life.
Researchers have designed multiplayer games occupants of autonomous vehicles can play with other players in nearby self-driving cars. A new study details three games created for level three and higher semi-autonomous vehicles. The researchers also made suggestions for many exciting types of in-car games for future exploration.
Semiconductors convert energy from photons into an electron current. However, some photons carry too much energy for the material to absorb. These photons produce 'hot electrons', and the excess energy of these electrons is converted into heat. Materials scientists have been looking for ways to harvest this excess energy. Scientists have now shown that this may be easier than expected.
At safe injection sites, medical staff are on hand at all times to reverse overdoses or treat injection-related wounds like collapsed veins and soft tissue infections. Kensington, a Northeastern Philadelphia neighborhood is one of the largest East Coast narcotic markets for opioids. Walking down the area's main street, Kensington Avenue, it is impossible to ignore the impact of opioids. Carelessl
There is plenty of fraud and corruption in the world, even in the halls of science. No one has a monopoly. But there are some hot spots that deserve specific attention. Recently significant concerns have been raised about the published research of Xuetao Cao, a Chinese Immunologist. This story is newsworthy because Cao is not just any immunologist – he is also the President of Nankai University,
The study marks the first instance of successfully using light to decode the activity of specific neuronal populations as well as manipulation of different brain regions with the use of an optical probe. The optical fibre is capable of capturing light from single neurons along regions as long as 2 millimetres (0.07 inches). The method enriches researchers' methodological repertoire and augments th
Facebook's NPE Team, a division inside the social networking giant that will build experimental consumer-facing social apps, has now added a third app to its lineup with the launch of …
Margays (Leopardus wiedii), small wild cats living in forest areas fragmented by agriculture near Campinas and Botucatu in São Paulo State, Brazil, prey on animals inhabiting nearby sugarcane plantations such as birds and small rodents.
Scientists at the TSU Laboratory of Biophotonics, working with Tomsk National Research Medical Center (TNIMC) oncologists, have developed a new approach to the diagnosis of adenocarcinoma, a malignant tumor of the prostate gland, that uses artificial intelligence to identify oncopathology and determine the stage of the disease. Using machine learning, a computer model was taught to distinguish bet
Margays (Leopardus wiedii), small wild cats living in forest areas fragmented by agriculture near Campinas and Botucatu in São Paulo State, Brazil, prey on animals inhabiting nearby sugarcane plantations such as birds and small rodents.
A better understanding of what gases to search for in exoplanet atmospheres is key to locating extraterrestrial life — Read more on ScientificAmerican.com
Nature, Published online: 19 November 2019; doi:10.1038/d41586-019-03527-y It's time to trust students to handle doubt and diversity in science, says Jerry Ravetz.
Over the past two decades, Americans have proved willing to do lots of things at Martha Stewart's behest. They will decoupage. They will make their own holiday wreaths. They will boil pasta and tomatoes in the same pot, at the same time . Perhaps most important for Stewart, they will buy things with her name on them—bedding, cookware, magazines. Soon they might even buy Martha Stewart–branded wee
A better understanding of what gases to search for in exoplanet atmospheres is key to locating extraterrestrial life — Read more on ScientificAmerican.com
Researchers at TU Delft's department of Precision and Microsystems Engineering (PME) have designed a dilation method that can be applied to any curved surface. This universal method may have a range of applications, including medical braces for children, expandable furniture or aortic stents. The method was published in Nature Communications on 15 November 2019.
Switching to renewables could cut the health impacts of air pollution from power generation as much as 80 percent by mid-century, experts said Tuesday.
Nature, Published online: 19 November 2019; doi:10.1038/d41586-019-03531-2 A hard-hitting study exposes the devastating effects of shame and discrimination. Julie Pulerwitz reviews.
PLUS. P+ er den nye pensionskasse for civilingeniører. Diplomingeniører i ISP har netop skiftet administrationsselskab og ønsker ikke at træffe en beslutning om at tilslutte sig P+, før årsregnskabet for 2020 er klar.
Plants are a rich source of compounds that may prove to have medicinal properties or serve as building blocks for new drugs to treat conditions like high cholesterol, cancer, and even viruses like Ebola. But as tropical rainforests are lost to fires and clearing, so too are diverse, unstudied plants species.
Health campaigns on social media aimed at increasing human papillomavirus (HPV) vaccination may see greater success, according to Drexel University researchers, if they inject a narrative into information-based posts.
A fight in Virginia Beach demonstrates the hard choices cities face when the pressure for new homes collides with the rising toll of natural disasters.
Der er gode penge at hente for kriminelle, hvis det lykkes dem at stjæle kontrollen over andres telefonnumre. Det vidner en ny sag fra USA om. Version2 har flere gange bevist, at denne type angreb er nemme at udføre i Danmark.
"America hired @realDonaldTrump to fire people like the first three witnesses we've seen," Donald Trump Jr. tweeted Friday. "Career government bureaucrats and nothing more." It was the second day of the House Intelligence Committee's impeachment hearings, and Marie Yovanovitch, a career diplomat who had served as the U.S. ambassador to Ukraine, had been called to testify about how the president's
At the core of many of America's most heated debates—affirmative action, voting rights, reparations—is an unsettled question the nation has wrestled with for nearly two centuries: Does the Constitution care about race? Or, put another way, is the Constitution color-blind? Supreme Court justices have weighed in frequently, perhaps most famously in John Marshall Harlan's renowned dissent in Plessy
Like many other correctional professionals, Sheriff Craig Apple of Albany County, New York, was initially suspicious of using drugs to treat drug addiction. He was considering the merits of introducing buprenorphine and methadone—two drugs used to treat opioid-use disorder—into the county's main jail facility, and wasn't sure he should, given that those drugs can become valuable and dangerous con
"A leader is best when people barely know he exists," Lao Tzu, the ancient Chinese philosopher and founder of Taoism, is thought to have said. "When his work is done, his aim fulfilled, they will say: 'We did it ourselves.''' But what if a leader doesn't exist at all? Around the world, leaderless protest movements have emerged, drawing tens of thousands (and, in some cases , millions) of people t
T he bedroom can seem to contain the heart of a marriage. In the 2012 Judd Apatow movie This Is 40 , the epicenter of marital tension is the bedroom of the onscreen couple, played by Paul Rudd and Leslie Mann. Pete and Debbie are as comely as their Los Angeles home, but the couple flirt with divorce fantasies more than with each other. Debbie mourns a loss of mystery; Pete craves independence. Of
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BioNyt Videnskabens Verden (www.bionyt.dk) er Danmarks ældste populærvidenskabelige tidsskrift for naturvidenskab. Det er det eneste blad af sin art i Danmark, som er helliget international forskning inden for livsvidenskaberne.
Bladet bringer aktuelle, spændende forskningsnyheder inden for biologi, medicin og andre naturvidenskabelige områder som f.eks. klimaændringer, nanoteknologi, partikelfysik, astronomi, seksualitet, biologiske våben, ecstasy, evolutionsbiologi, kloning, fedme, søvnforskning, muligheden for liv på mars, influenzaepidemier, livets opståen osv.
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Tegn abonnement på
BioNyt Videnskabens Verden (www.bionyt.dk) er Danmarks ældste populærvidenskabelige tidsskrift for naturvidenskab. Det er det eneste blad af sin art i Danmark, som er helliget international forskning inden for livsvidenskaberne.
Bladet bringer aktuelle, spændende forskningsnyheder inden for biologi, medicin og andre naturvidenskabelige områder som f.eks. klimaændringer, nanoteknologi, partikelfysik, astronomi, seksualitet, biologiske våben, ecstasy, evolutionsbiologi, kloning, fedme, søvnforskning, muligheden for liv på mars, influenzaepidemier, livets opståen osv.
Artiklerne roses for at gøre vanskeligt stof forståeligt, uden at den videnskabelige holdbarhed tabes.
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