Proteasome inhibitors, such as bortezomib (BTZ), are highly effective and widely used treatments for multiple myeloma. One proposed reason for myeloma cells' exceptional sensitivity to proteasome inhibition is that they produce and continually degrade unusually large amounts of abnormal immunoglobulins. We, therefore, hypothesized that, heat shock may also be especially…
Syntaxin17, a key autophagosomal N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) protein, can associate with ATG8 family proteins SNAP29 and VAMP8 to facilitate the membrane fusion process between the double-membraned autophagosome and single-membraned lysosome in mammalian macroautophagy. However, the inherent properties of Syntaxin17 and the mechanistic basis underlying the
Loss of the von Hippel–Lindau (VHL) tumor suppressor is a hallmark feature of renal clear cell carcinoma. VHL inactivation results in the constitutive activation of the hypoxia-inducible factors (HIFs) HIF-1 and HIF-2 and their downstream targets, including the proangiogenic factors VEGF and PDGF. However, antiangiogenic agents and HIF-2 inhibitors have…
Arabidopsis AINTEGUMENTA (ANT), an AP2 transcription factor, is known to control plant growth and floral organogenesis. In this study, our transcriptome analysis and in situ hybridization assays of maize embryonic leaves suggested that maize ANT1 (ZmANT1) regulates vascular development. To better understand ANT1 functions, we determined the binding motif of…
Rod photoreceptors are composed of a soma and an inner segment (IS) connected to an outer segment (OS) by a thin cilium. OSs are composed of a stack of ∼800 lipid discs surrounded by the plasma membrane where phototransduction takes place. Intracellular calcium plays a major role in phototransduction and…
We tested cis-ApcΔ716/Smad4+/− and cis-ApcΔ716/Smad4+/− KrasG12D mice, which recapitulate key genetic abnormalities accumulating during colorectal cancer (CRC) tumorigenesis in humans, for responsiveness to anti-VEGF therapy. We found that even tumors in cis-ApcΔ716/Smad4+/− KrasG12D mice, although highly aggressive, were suppressed by anti-VEGF treatment. We tested the hypothesis that inflammatio
Organic electronic devices implemented on flexible thin films are attracting increased attention for biomedical applications because they possess extraordinary conformity to curved surfaces. A neuronal device equipped with an organic light-emitting diode (OLED), used in combination with animals that are genetically engineered to include a light-gated ion channel, would enable…
A new study is helping scientists piece together the ancient climate of Mars by revealing how much rainfall and snowmelt filled its lake beds and river valleys 3.5 billion to 4 billion years ago.
Are there parallels between the furthest reaches of our universe, and the foundations of thought, awareness, perception, and emotion? What are the connections between the webs and structures that define both? What are the differences? "As Above As Below" was an exhibition that examined these questions. It consisted of six artworks, each of them the product of a collaboration that included at least
Every weekday evening, our editors guide you through the biggest stories of the day, help you discover new ideas, and surprise you with moments of delight. Subscribe to get this delivered to your inbox . Getty / Paul Spella / The Atlantic Today, Ed Yong, our staff writer whose coverage of this pandemic has been essential to understanding it , is back with a new piece about long-haulers. It's wort
Women with a history of high blood pressure disorders during pregnancy are more likely to experience bothersome menopausal symptoms such as hot flashes and night sweats, according to a new study.
Encouraging the public to see face masks as a social practice, which they can use to express their cultural background or their personality, could encourage more people to use them regularly, say researchers writing in The BMJ today.
What do anti-vaxxers and anti-GMO campaigners have in common? Underpinning both "antis" is a shared belief that because vaccines and GMOs are "unnatural," they're bad, which for many people—whatever their feelings about vaccines and GMOs—segues into its inverse: What's natural is good. Shades of Rousseau's exaltation of the noble savage, within us and without. It's an easy conclusion, often appro
Our human world is soaked in light. For starters there are the 100,000 trillion photons arriving every second at every square centimeter of Earth's dayside surface, after racing here from the outer envelope of a natural giant thermonuclear reactor we call the sun. There are also the photons that zip every which way through any cubic centimeter of open space. Some of these are the microwave leftov
In January, Robert Williams, an African-American man, was wrongfully arrested due to an inaccurate facial recognition algorithm, a computerized approach that analyzes human faces and identifies them by comparison to database images of known people. He was handcuffed and arrested in front of his family by Detroit police without being told why, then jailed overnight after the police took mugshots,
Preterm and early term delivery are independent risk factors for premature death in women up to 40 years later, finds a study from Sweden published by The BMJ today.
Children exposed to higher levels of fine particles in the air (known as PM2.5) are more likely to develop asthma and persistent wheezing than children who are not exposed, finds a study published by The BMJ today.
What's new: Dozens of countries have rolled out automated contact tracing apps, but a new study confirms what experts already knew: they can't beat the pandemic on their own. According to a new systematic review of 15 published studies, the technology still requires manual contact tracing, social distancing, and mass testing in order to be effective. The new research , from University College Lon
Rising temperatures due to our greenhouse gas emissions can cause greater damages to our economies than previous research suggested, a new study shows.
Hi everyone. I am The Economist's deputy editor, and editor of our annual future-gazing supplements, The World If and The World In. This year's World If supplement presented a series of imagined scenarios around the topic of climate change. We explored what might happen if technology tracked all carbon emissions , the Republican party got serious about climate change , or carbon removal became th
From now on with the exception of – news of new technological developments or major unique news events relating to climate change – we're going to put all other climate change posts in their own weekly mega thread. 17/08 – Coal's Days May Be Over in the U.S 19/08 – City Councilor Michelle Wu Pitches 'Green New Deal' for Boston submitted by /u/FuturologyModBot [link] [comments]
There are three solutions to this maze. Can you solve them all? (Glenn Orzepowski/) We know you are bored at home right now—we are too. Here are some puzzles and brainteasers to challenge your family and friends with, either in person or over video chat. Humans have meandered through mazes for thousands of years, whether they be ancient Egyptian labyrinths, a Minotaur's lair, passageways carved i
Like biological fat reserves store energy in animals, a new rechargeable zinc battery integrates into the structure of a robot to provide much more energy, researchers have shown.
Between 2017 and 2030, an estimated 6.8 million fewer female births will be recorded in India than would be by chance, due to sex-selective abortions, according to a new study.
Nature, Published online: 19 August 2020; doi:10.1038/d41586-020-02324-2 Researchers call for more rigorous clinical trials as rumours abound that US regulators are considering widening access to the potential therapy.
Geographers offer first-hand accounts of what is required for GIS instructors and IT administrators to set up virtual computing specifically for providing state-of-the-art geographic information systems (GIS) instruction.
A recent study suggests transmission of COVID-19 through breast milk is not likely. The infectious virus was not detected in 64 samples of breast milk tested.
The flashy Flamboyant Cuttlefish is among the most famous of the cephalopods (octopus, squid, and cuttlefish) – but it is widely misunderstood by its legions of fans. A new article sets the record straight.
How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist. The research has implications for how epigenetic factors relate to aging.
A retro game champion is suspected of killing an ex-girlfriend and then himself. Gamers now say they warned others about his threatening behavior for years.
Skilled in the conciseness of Instagram, TikTok, and Twitter, the congressperson said all she needed to say in the short time she was given at the DNC.
Many academic institutions are failing to address the most common forms of gender-based harassment: behaviors that communicate derision, disgust or disrespect for members of one sex or gender group.
A new study from The University of Texas at Austin is helping scientists piece together the ancient climate of Mars by revealing how much rainfall and snowmelt filled its lake beds and river valleys 3.5 billion to 4 billion years ago.
A longstanding theory has suggested that gastric bypass surgery may have unique, weight loss-independent effects in treating type 2 diabetes. But new research from Washington University School of Medicine in St. Louis indicates that weight loss after surgery, rather than the surgery itself, drives metabolic improvements, such as the remission of diabetes.
Widespread layoffs amid the COVID-19 pandemic threaten to cut off millions of people from their employer-sponsored health insurance plans. But the Affordable Care Act (ACA) will protect many of these people and their families from losing coverage, according to a new study.
A team of scientists at the University of Michigan have created "biomorphic batteries" that allow robots to store energy like humans — in fat reserves spread across their bodies. The idea is to greatly increase the battery capacity of robots by mimicking the distributed energy sources of living beings, and as it turns out, the new batteries may also hold far more power than the conventional lithi
How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist at the University of California, Riverside. The research has implications for how epigenetic factors relate to aging.
The flashy Flamboyant Cuttlefish is among the most famous of the cephalopods (octopus, squid, and cuttlefish) – but it is widely misunderstood by its legions of fans. A new paper from the Roger Hanlon laboratory at the Marine Biological Laboratory, Woods Hole, sets the record straight.
A new analysis published in Public Administration found that student graduation rates improve as more faculty employed by a college or university share sex and race/ethnic identities with students.
The rapid pace that invasive shrubs infiltrate forests in the northeastern United States makes scientists suspect they have a consistent advantage over native shrubs, and the first region-wide study of leaf timing supports those suspicions.
For decades, physicians have known that many kinds of cancer cells often spread first to lymph nodes before traveling to distant organs through the bloodstream. New research provides insight into why this occurs, opening up new targets for treatments that could inhibit the spread of cancer.
Bacteria that can help defuse highly toxic dioxin in sediments in the Passaic River – a Superfund hazardous waste site – could eventually aid cleanup efforts at other dioxin-contaminated sites around the world, according to scientists.
Medical researchers are tracking the onset of ataxias. The results provide valuable data for prevention studies. The data were collected by a research network, which includes scientific institutions from Austria, France, Germany, Hungary, Italy, Poland and Spain.
Physicians have discovered how the communication between individual cells can be influenced with the help of a specific protein. These findings are an important approach to improving the treatment of diseases such as arteriosclerosis (calcified blood vessels), which causes heart attacks.
Bacteria that can help defuse highly toxic dioxin in sediments in the Passaic River – a Superfund hazardous waste site – could eventually aid cleanup efforts at other dioxin-contaminated sites around the world, according to scientists.
Policy reforms and technological improvements could drive seafood production upward by as much as 75% over the next three decades, research by Oregon State University and an international collaboration suggests.
An open-source educational biotechnology called the "Genetic Code Kit" has been developed by California Polytechnic State University researchers to allow students to interact with the molecular process inside cells in new ways. Researchers show that adapting state-of-the-art biotechnology for the classroom could transform how biology and biochemistry are taught to high school and undergraduate stu
Crews were battling wildfires in the San Francisco Bay Area and thousands of people were under orders to evacuate as dozens of wildfires blazed across the state amid a blistering heat wave now in its second week.
In an important step toward practical implementation of secure quantum-based communication, researchers have demonstrated secure measurement-device-independent quantum key distribution (MDI-QKD) transmission over a record-breaking 170 kilometers.
An open-source educational biotechnology called the "Genetic Code Kit" has been developed by California Polytechnic State University researchers to allow students to interact with the molecular process inside cells in new ways. Researchers show that adapting state-of-the-art biotechnology for the classroom could transform how biology and biochemistry are taught to high school and undergraduate stu
Astronomers have used NASA's Chandra X-ray Observatory to record material blasting away from the site of an exploded star at speeds faster than 20 million miles per hour. This is about 25,000 times faster than the speed of sound on Earth.
The rapid pace that invasive shrubs infiltrate forests in the northeastern United States makes scientists suspect they have a consistent advantage over native shrubs, and the first region-wide study of leaf timing, conducted by Penn State researchers, supports those suspicions.
The rapid pace that invasive shrubs infiltrate forests in the northeastern United States makes scientists suspect they have a consistent advantage over native shrubs, and the first region-wide study of leaf timing, conducted by Penn State researchers, supports those suspicions.
A robust, low-cost imaging platform utilizing lab-on-a-chip technology may be available for rapid coronavirus diagnostic and antibody testing throughout the nation by the end of the year.
Researchers have discovered that removing copper from the blood can destroy some of the deadliest cancers that are resistant to immunotherapy using models of the disease.
Researchers have found their previous discovery of bacteria living on air in Antarctica is likely a process that occurs globally, further supporting the potential existence of microbial life on alien planets.
A research group elucidated the brain circuit mechanism that cause of spatial memory impairment in Alzheimer's disease. In the future, improving brain remapping function may reverse spatial memory impairment in patients with Alzheimer's disease.
The size of salmon returning to rivers in Alaska has declined dramatically over the past 60 years because they are spending fewer years at sea, scientists report. Salmon are critically important to both people and ecosystems in Alaska, supporting commercial and subsistence fisheries and transporting nutrients from the ocean to inland areas. Smaller salmon provide less food for people who depend on
Science is suffering from a replication crisis. Too many landmark studies can't be repeated in independent labs, a process crucial to separating flukes and errors from solid results. The consequences are hard to overstate: Public policy, medical treatments and the way we see the world may have been built on the shakiest of foundations.
In a new paper this week, geographer Forrest Bowlick at the University of Massachusetts Amherst and colleagues at Texas A&M offer first-hand accounts of what is required for GIS instructors and IT administrators to set up virtual computing specifically for providing state-of-the-art geographic information systems (GIS) instruction.
A robust, low-cost imaging platform utilizing lab-on-a-chip technology created by University of California, Irvine scientists may be available for rapid coronavirus diagnostic and antibody testing throughout the nation by the end of the year.
A recent study by researchers at University of California San Diego School of Medicine suggests transmission of COVID-19 through breast milk is not likely. The infectious virus was not detected in 64 samples of breast milk tested.
An open-source educational biotechnology called the 'Genetic Code Kit' allows students to interact with the molecular process inside cells in new ways. Researchers show that adapting state-of-the-art biotechnology for the classroom could transform how biology and biochemistry are taught to high school and undergraduate students.
In a new paper this week, geographer Forrest Bowlick at the University of Massachusetts Amherst and colleagues at Texas A&M offer first-hand accounts of what is required for GIS instructors and IT administrators to set up virtual computing specifically for providing state-of-the-art geographic information systems (GIS) instruction.
Stroke is the leading cause of disability in the US; new research from UConn Health suggests a promising treatment for patients by successfully inhibited an important receptor implicated in post-stroke damage and recovery.
While movement problems are the main symptoms of Parkinson's disease, people with the disease often have non-motor symptoms such as constipation, daytime sleepiness and depression 10 or more years before the movement problems start. A new study suggests that eating a healthy diet in middle age may be linked to having fewer of these preceding symptoms. The study is published in the August 19, 2020,
Disturbed sleep patterns do not cause Alzheimer's disease but people who are at high genetic risk of developing Alzheimer's disease may be more likely to be a 'morning person,' have shorter sleep duration and other measures of sleep disturbance and are less likely to have insomnia, according to a study published in the August 19, 2020, online issue of Neurology®, the medical journal of the America
The EPA finalized the rule change this week after foreshadowing it for several months. (Environmental Protection Agency/) Jeremy Deaton writes for Nexus Media, a nonprofit climate change news service. You can follow him @deaton_jeremy . This story was published in partnership with Nexus Media . This year, levels of methane, a powerful heat-trapping gas, hit an all-time high , driven in large part
A robust, low-cost imaging platform utilizing lab-on-a-chip technology created by University of California, Irvine scientists may be available for rapid coronavirus diagnostic and antibody testing throughout the nation by the end of the year.
The COVID-19 pandemic has brought about rapid innovation in mental health care, and the move to telemedicine is likely here to stay to at least some degree, but new research cautions that serious barriers still need to be overcome.
Researchers have created and characterized a new mouse replica of Down syndrome, long considered one of the most challenging disorders to simulate in laboratory animals.
Research has shown that two proteins found in deceased donor urine can be measured to define which donor organs — including those with AKI — are the best candidates for saving the lives of patients with kidney failure.
Opioid use among women trying to conceive may be associated with a lower chance of pregnancy, suggests a new study. Moreover, opioid use in early pregnancy may be associated with a greater chance of pregnancy loss.
Incredible Immersion NASA wants to take a fresh look at some distant galaxies. When the James Webb Space Telescope launches, the space agency plans to use it to capture 3D images of three distant quasars and the host galaxies that swirl around them. The new images, NASA hopes, will help finally explain how, exactly, these bizarre supermassive black holes shape and reshape their galaxies. All For
The discovery of an unprecedented physical effect in a new artificial material marks a significant milestone in the lengthy process of developing 'made-to-order' materials and more energy-efficient electronics.
Light Snack While they were trying to find ways to clean the Passaic River Superfund site, a team of scientists discovered a new bacterium that might be able too do some of the heavy lifting on similar sites. The bacteria was found thriving in toxic mud at the bottom of the river, where it was happily munching away on cancer-causing and otherwise dangerous toxins called dioxins, according to rese
An international team of scientists has tested state-of-the-art machine learning algorithms for the challenging tasks of determining the mental workload and affective states of a human brain. Their software can help design smarter brain-computer interfaces for applications in medicine and beyond. In the next steps, researchers plan to use more sophisticated artificial intelligence (AI) methods, es
The Fastest Charger Electric car company Lucid Motors claims that that its Lucid Air luxury sedan "will be the fastest charging electric vehicle ever offered with the capability to charge at rates of up to 20 miles per minute," according to a press release. That's about 300 miles of range in just 20 minutes of charging, according to the company, which is making a pretty big deal out of its upcomi
Panning For Neutrinos When an ambitious new Fermilab experiment called DUNE (Deep Underground Neutrino Experiment) begins its work, physicists believe they'll be able to learn a whole lot more about supernova explosions than ever before. That's because DUNE, an underground facility in Illinois, is expected to be sensitive to an extremely elusive particle called a neutrino that's blasted far and w
Shielding stem cells with a new biomaterial improves their ability to heal heart attack damage, a new study with rodents shows. Researchers showed they could make capsules of wound-healing mesenchymal stem cells (MSCs) and implant them next to wounded hearts using minimally invasive techniques. Within four weeks, they saw heart healing 2.5 times greater in animals treated with shielded stem cells
Data from the first COVID-19 patients treated at three large Massachusetts hospitals reveal important trends, including disproportionate representation of vulnerable populations, high rates of disease-related complications, and the need for post-discharge, post-acute care and monitoring.
A new study calculates the lifetime risk of death from firearms and drug overdoses in the United States. The lifetime risk of death from firearms is about one percent, and the lifetime risk of death from drug overdoses is 1.5 percent, according to the study.
Reporting on the first community-wide assessment of 67 bee species of the Colorado Rockies, ecologists say 'phenological mismatch,' changing timing of life cycles between bees and flowers, caused by climate change, has the potential to disrupt a mutually beneficial relationship.
Scientists provide the first interdisciplinary assessment of human involvement into the terrestrial vertebrate trade in Laos and its impact on the survival of the local fauna populations. Sixty-six traded species found on wildlife trade markets were documented, and more than half of them were found to be the species protected either by national law or international convention.
If you've ever been woken up before sunrise by the chirping of birds outside your window, you may have wondered: why do birds sing so loud, so early in the morning? The cacophony is mostly males, whose songs are meant to impress potential mates and rivals. Researchers say there may be a good reason why birds are most vocal at first light. By singing early and often, birds perform better during the
Even for infants just beginning to speak their first words, the way an object is named guides infants' encoding, representation and memory for that object, according to new research. Encoding objects in memory and recalling them later is fundamental to human cognition and emerges in infancy. Evidence from a new recognition memory task reveals that as they encode objects, infants are sensitive to a
Researchers, in a recent study, were surprised to learn that they could take the exact same number of seeds from the same plants, put them in agricultural fields across the Mid-Atlantic region and get profoundly different stands of cover crops a few months later.
Researchers have developed a new instrument that has, for the first time, measured tiny light-evoked deformations in individual rods and cones in a living human eye. The new approach could one day improve detection of retinal diseases such as age-related macular degeneration, a leading cause of blindness in people over 55 worldwide.
As the climate of the planet is changing, many researchers are looking to more renewable energy sources. Researchers investigate whether the power generated by solar and wind farms would differ between current and future climates. The researchers focused on sites in Australia where variable renewable generators are located or are likely to be located in the future based on the Australian Energy Ma
As soon as the foodborne pathogen Vibrio parahaemolyticus infects a human intestinal cell, the bacteria are already planning their escape. After all, once it is in and multiplies, the bacterium must find a way out to infect new cells.
Just north of the Golden Gate Bridge, yet a world away from San Francisco, in an unincorporated and oft-overlooked area known as Marin City, sea level rise is rarely the first worry that comes to mind.
A new study by investigators from Brigham and Women's Hospital uncovered a group of closely related genes that may capture molecular links between Alzheimer's disease and Limbic-predominant Age-related TDP-43 Encephalopathy, or LATE, a recently recognized common brain disorder that can mimic Alzheimer's symptoms.
The rapid pace that invasive shrubs infiltrate forests in the northeastern United States makes scientists suspect they have a consistent advantage over native shrubs, and the first region-wide study of leaf timing, conducted by Penn State researchers, supports those suspicions.
For many couples, moving in together signifies a big step in the relationship. Traditionally, this meant marriage, although nowadays most cohabit before getting married, or splitting up. But there is a third choice: living apart together. Not only is it surprisingly common , but living apart together is increasingly seen as a new and better way for modern couples to live . Surveys have previously
NASA-NOAA's Suomi NPP satellite kept an eye on Hurricane Genevieve overnight and provided infrared imagery to forecasters who were monitoring the storm's strength, structure and size. Because Genevieve is close to the coast of western Mexico, warnings and watches were still in effect.
Social adversity in early childhood appears to be a significant risk factor for death in early adulthood. Children who have experienced repeated serious adversity such as losing a parent, mental illness in the family, poverty or being placed in foster care have a 4.5 times higher risk of dying in early adulthood than children who have not experienced adversity during childhood.
Combing through historical seismic data, researchers using a machine learning model have unearthed distinct statistical features marking the formative stage of slow-slip ruptures in the earth's crust months before tremor or GPS data detected a slip in the tectonic plates.
A new study upends the widely held belief that a medication used to treat lymphatic filariasis doesn't directly target the parasites that cause the disease. The research shows the medication, diethylcarbamazine, temporarily paralyzes the parasites.
Older adults' regular visits to eateries such as fast food restaurants and coffee shops may be as protective of cognitive health as marriage, according to new research. Researchers interviewed 125 older adults ages 55-92 in the Minneapolis metro area and accompanied them on visits to their neighborhood haunts. Through analysis of the interviews, they found that older adults valued these types of
Multiple major wildfires are currently burning out of control in the state of California, and the resources needed to contain the fires are being stretched thin. Many of the blazes, driven by high winds amid hot and dry conditions, are believed to have been started by lightning. Thousands of residents have been ordered to evacuate, as heavy smoke blankets the San Francisco Bay Area. Gathered here
Wellcome Trust director says government should have waited for public inquiry Coronavirus – latest updates See all our coronavirus coverage The abolition of Public Health England is a kneejerk attempt to blame it for mistakes made over coronavirus, one of the government's key advisers on the crisis has alleged. Jeremy Farrar, a member of the Scientific Advisory Group on Emergencies (Sage), critic
Powerful Hurricane Genevieve began flinging rain at Mexico's Baja California Peninsula on Wednesday and it threatened to bring hurricane-force winds to the tourist region even if its center wasn't likely to hit land.
California staved off another round of rolling blackouts as a searing heat wave strained its electrical grid, but authorities warned of a continuing threat Wednesday.
A new approach to a surgical procedure required for dialysis offers better long-term viability and a lower chance of complications compared with conventional techniques, according to work involving rats and 274 patients.
New research on the fin development of the Australian lungfish by an international team of researchers from the University of Konstanz (Germany), Macquarie University in Sydney (Australia) and the Stazione Zoologica Anton Dohrn in Naples (Italy) elucidates how fins evolved into limbs with hands with digits. The main finding is that in lungfish a primitive hand is already present, but that function
Babies that experience low oxygen levels in the womb due to pregnancy complications often go on to develop heart disease in adulthood. A study using sheep has discovered that a specialised antioxidant called MitoQ can prevent heart disease at its very onset. The results are published today in the journal Science Advances.
An analysis of facial expressions in ancient Mesoamerican sculptures finds that some emotions expressed in these artworks match the emotions that modern US participants would anticipate for each discernible context, including elation, sadness, pain, anger, and determination or strain. For instance, elation was predicted in the context of social touch while anger was
Like biological fat reserves store energy in animals, a new rechargeable zinc battery integrates into the structure of a robot to provide much more energy, a team led by the University of Michigan has shown.
A new study of Black residents of four distinct US cities reveals variations in genetic ancestry and social status that underscore the inadequacy of using skin color as a proxy for race in research. Dede Teteh of City of Hope Medical Center in Duarte, California, and colleagues present these findings in the open-access journal PLOS ONE on August 19, 2020.
Between 2017 and 2030, an estimated 6.8 million fewer female births will be recorded in India than would be by chance, due to sex-selective abortions, according to a new study published August 19, 2020 in the open-access journal PLOS ONE by Fengqing Chao of King Abdullah University of Science and Technology (KAUST), Saudi Arabia, and colleagues.
Researchers have developed the highly sensitive ORIGIN instrument, which can provide proof of the smallest amounts of traces of life, for future space missions. The instrument may be used on missions to the ice moons of Europa (Jupiter) and Enceladus (Saturn), for example.
A radiologist and an evolutionary anatomist have teamed up to show the same techniques used for research on reptile and bird lungs can be used to help confirm the diagnosis of COVID-19 in patients. Their paper demonstrates that 3D models are a strikingly clearer method for visually evaluating the distribution of COVID-19-related infection in the respiratory system.
Researchers have found a treatment that increases the speed of nerve regeneration by three to five times, leading to much better outcomes for trauma surgery patients.
Demand for food is set to rise substantially in the coming decades, which raises a question: How well can the ocean fill the gap between current supply and future need?
NASA JPL are developing autonomous capabilities that could allow future Mars rovers to go farther, faster and do more science. Training machine learning models on the Maverick2, their team developed and optimized models for Drive-By Science and Energy-Optimal Autonomous Navigation.
Unlike chimpanzees in East and West Africa, who use a single tool to extract termites, chimpanzees in Central Africa's Congo Basin use tool sets — puncturing sticks or perforating twigs plus fishing probes — to harvest the insects from underground nests or towering earthen mounds scattered across lowland forests.
Scientists have made a major advance in the pursuit of a safe and effective treatment for type 1 diabetes, an illness that impacts an estimated 1.6 million Americans with a cost of $14.4 billion annually. Using stem cell technology, researchers generated the first human insulin-producing pancreatic cell clusters able to evade the immune system. These 'immune shielded' cell clusters controlled bloo
In infectious disease outbreaks, digital contact tracing alone could reduce the number of cases, but not as much as manual contract tracing, new research reveals.
A new standard for how videos are sent through the internet and read by your computer could make the digital world more inclusive, says media scholar Jason Schmitt.
Discovery of marked plaquettes at Les Varines points to earliest evidence of human art in British Isles They are small, flat and covered in what appear to be chaotic scratches, but 10 engraved stone fragments unearthed in Jersey, researchers say, could be the earliest evidence of human art in the British Isles. The stones were found at Les Varines, on the island, between 2014 and 2018, and are be
Urban theory models cities as spatial equilibria to derive their aggregate properties as functions of extensive variables, such as population size. However, this assumption seems at odds with cities' most interesting properties as engines of fast and variable processes of growth and change. Here, we build a general statistical dynamics of cities across scales, from single agents to entire urban s
Maternal immune activation increases the risk of neurodevelopmental disorders. Elevated cytokines, such as interferon- (IFN-), in offspring's brains play a central role. IFN- activates an antiviral cellular state, limiting viral entry and replication. Moreover, IFN- is implicated in brain development. We tested the hypothesis that IFN- signaling contributes to molecular and cellular phenotypes as
Brownian motion of particles in fluid is the most common form of collective behavior in physical and biological systems. Here, we demonstrate through both experiment and numerical simulation that the movement of vortices in a rotating turbulent convective flow resembles that of inertial Brownian particles, i.e., they initially move ballistically and then diffusively after certain critical time. M
Central to the study of emotion is evidence concerning its universality, particularly the degree to which emotional expressions are similar across cultures. Here, we present an approach to studying the universality of emotional expression that rules out cultural contact and circumvents potential biases in survey-based methods: A computational analysis of apparent facial expressions portrayed in a
The prenatal origins of heart disease in offspring have been established. However, research in species with developmental milestones comparable to humans is lacking, preventing translation of this knowledge to clinical contexts. Using sheep and chickens, two species with similar cardiovascular developmental milestones to humans, we combined in vivo experiments with in vitro studies at organ, cell
Development of the new-generation membranes for tunable molecular separation requires materials with abilities beyond strict separation. Stimuli response could remotely adjust the membrane selectivity. Azobenzene derivatives can be photo-switched between trans and cis isomers under ultraviolet or visible light. Here, the azobenzenes were implanted as light switches to bridge the flexible cyclen b
Humans learn from their own trial-and-error experience and observing others. However, it remains unknown how brain circuits compute expected values when direct learning and social learning coexist in uncertain environments. Using a multiplayer reward learning paradigm with 185 participants (39 being scanned) in real time, we observed that individuals succumbed to the group when confronted with di
Diagnostic imaging often outperforms the surgeon's ability to identify small structures during therapeutic procedures. Smart soft tissue markers that translate the sensitivity of diagnostic imaging into optimal therapeutic intervention are therefore highly warranted. This paper presents a unique adaptable liquid soft tissue marker system based on functionalized carbohydrates (Carbo-gel). The liqu
Tendon inserts into bone via a fibrocartilaginous interface (enthesis) that reduces mechanical strain and tissue failure. Despite this toughening mechanism, tears occur because of acute (overload) or degradative (aging) processes. Surgically fixating torn tendon into bone results in the formation of a scar tissue interface with inferior biomechanical properties. Progress toward enthesis regenerat
Flexible sensors are highly desirable for tactile sensing and wearable devices. Previous researches of smart elements have focused on flexible pressure or temperature sensors. However, realizing material identification remains a challenge. Here, we report a multifunctional sensor composed of hydrophobic films and graphene/polydimethylsiloxane sponges. By engineering and optimizing sponges, the fa
Three types of seemingly unyielding trade-offs have continued to challenge the rational design for circular polymers with both high chemical recyclability and high-performance properties: depolymerizability/performance, crystallinity/ductility, and stereo-disorder/crystallinity. Here, we introduce a monomer design strategy based on a bridged bicyclic thiolactone that produces stereo-disordered to
Some photonic systems support bound states in the continuum (BICs) that have infinite lifetimes, although their frequencies and momenta are matched to vacuum modes. Using a prototypical system that can be treated analytically, we show that each of these BICs always splits into a pair of new type BIC and lasing threshold mode when a parity-time (PT)–symmetric perturbation is introduced. The radiat
How the hand and digits originated from fish fins during the Devonian fin-to-limb transition remains unsolved. Controversy in this conundrum stems from the scarcity of ontogenetic data from extant lobe-finned fishes. We report the patterning of an autopod-like domain by hoxa13 during fin development of the Australian lungfish, the most closely related extant fish relative of tetrapods. Difference
Maintaining biocatalyst stability and activity is a critical challenge. Chondroitinase ABC (ChABC) has shown promise in central nervous system (CNS) regeneration, yet its therapeutic utility is severely limited by instability. We computationally reengineered ChABC by introducing 37, 55, and 92 amino acid changes using consensus design and forcefield-based optimization. All mutants were more stabl
While N 6 -methyladenosine (m 6 A) is the most prevalent modification of eukaryotic messenger RNA (mRNA) involved in various cellular responses, its role in modulating bacteria-induced inflammatory response remains elusive. Here, we showed that loss of the m 6 A reader YTH-domain family 2 (YTHDF2) promoted demethylation of histone H3 lysine-27 trimethylation (H3K27me3), which led to enhanced prod
Inflammation triggers degradation of intervertebral disc extracellular matrix (ECM), a hallmark of disc degeneration that contributes to back pain. Mechanosensitive nucleus pulposus cells are responsible for ECM production, yet the impact of a proinflammatory microenvironment on cell mechanobiology is unknown. Using gain- and loss-of-function approaches, we show that tumor necrosis factor–α (TNFα
Colliding drops are encountered in everyday technologies and natural processes, from combustion engines and commodity sprays to raindrops and cloud formation. The outcome of a collision depends on many factors, including the impact velocity and the degree of alignment, and intrinsic properties like surface tension. Yet, little is known on binary impact dynamics of low-surface-tension drops on a l
ESCRT-III proteins mediate a range of cellular membrane remodeling activities such as multivesicular body biogenesis, cytokinesis, and viral release. Critical to these processes is the assembly of ESCRT-III subunits into polymeric structures. In this study, we determined the cryo-EM structure of a helical assembly of Saccharomyces cerevisiae Vps24 at 3.2-Å resolution and found that Vps24 adopts a
Catalytically inactive dCas9 fused to transcriptional activators (dCas9-VPR) enables activation of silent genes. Many disease genes have counterparts, which serve similar functions but are expressed in distinct cell types. One attractive option to compensate for the missing function of a defective gene could be to transcriptionally activate its functionally equivalent counterpart via dCas9-VPR. K
Membrane separation technology is dictated by the permeability-selectivity trade-off rule, because selectivity relies on membrane pore size being smaller than that of hydrated ions. We discovered a previously unknown mechanism that breaks the permeability-selectivity trade-off in using a rotating nanoporous graphene membrane with pores of 2 to 4 nanometers in diameter. The results show that the r
In social insects, workers and queens arise from the same genome but display profound differences in behavior and longevity. In Harpegnathos saltator ants, adult workers can transition to a queen-like state called gamergate, which results in reprogramming of social behavior and life-span extension. Using single-cell RNA sequencing, we compared the distribution of neuronal and glial populations be
A new species of isopod with a resemblance to a certain Sith lord was just discovered. It is the first known giant isopod from the Indian Ocean. The finding extends the list of giant isopods even further. Humanity knows surprisingly little about the ocean depths. An often-repeated bit of evidence for this is the fact that humanity has done a better job mapping the surface of Mars than the bottom
The evolution of limbs with functional digits from fish fins happened approximately 400 million years ago in the Devonian. This morphological transition allowed vertebrates to leave the water to conquer land and gave rise to all four-legged animals or tetrapods—the evolutionary lineage that includes all amphibians, reptiles, birds and mammals (including humans). Since the nineteenth century severa
Newly published research in Science Advances by University of Chicago researcher Luis Bettencourt proposes a new perspective and models on several known paradoxes of cities. Namely, if cities are engines of economic growth, why do poverty and inequality persist? If cities thrive on faster activity and more diversity, why are so many things so hard to change? And if growth and innovation are so imp
The evolution of limbs with functional digits from fish fins happened approximately 400 million years ago in the Devonian. This morphological transition allowed vertebrates to leave the water to conquer land and gave rise to all four-legged animals or tetrapods—the evolutionary lineage that includes all amphibians, reptiles, birds and mammals (including humans). Since the nineteenth century severa
Young gay men who are uncomfortable discussing sexual issues with their primary care providers and experience health care discrimination are less likely to seek coordinated care, leading to missed opportunities for early diagnosis of chronic and mental health issues, according to Rutgers researchers.
According to ARRS' American Journal of Roentgenology (AJR), the eConsult electronic consultation system allowed primary care providers to easily consult with radiologists, was perceived as high value by primary care providers, resulted in altered patient management, and avoided unnecessary imaging tests. "We identified follow-up imaging of cystic lesions and imaging workup of pain in patients as o
Data from the first COVID-19 patients treated at three large Massachusetts hospitals reveal important trends, including disproportionate representation of vulnerable populations, high rates of disease-related complications, and the need for post-discharge, post-acute care and monitoring.
NASA-NOAA's Suomi NPP satellite kept an eye on Hurricane Genevieve overnight and provided infrared imagery to forecasters who were monitoring the storm's strength, structure and size. Because Genevieve is close to the coast of western Mexico, warnings and watches were still in effect.
A team of Stanford researchers have created a tiny "hydrodynamic treadmill," essentially an endless loop of water, to closely observe the behavior of marine microorganisms. "This is a completely new way of studying life in the ocean," Deepak Krishnamurthy, Stanford mechanical engineering PhD student, and first author of the paper published in Nature Methods on Monday, said in a statement . "It op
The Pappy Lane shipwreck, as seen from above. (John McCord/) Thousands of vessels are submerged in the waters off the coast of North Carolina. The Outer Banks, with its strong currents and storms that create treacherous conditions for ships, is nicknamed "The Graveyard of the Atlantic." However, many of these wrecks have taken on new duties by providing valuable habitat for fish and other marine
The narrative in the US that the Chinese don't care about data privacy is simply misguided. It's true that the Chinese government has built a sophisticated surveillance apparatus (with the help of Western companies), and continues to spy on its citizenry. But when it comes to what companies can do with people's information, China is rapidly moving toward a data privacy regime that, in aligning wi
They include getting your own Netflix show. Nasser, a science journalist known for his work on "Radiolab," talked about going on-camera for "Connected" and the importance of staying curious.
In a step closer to skyscrapers that serve as power sources, researchers have set a new efficiency record for color-neutral, transparent solar cells. The team achieved 8.1% efficiency and 43.3% transparency with an organic, or carbon-based, design rather than conventional silicon. While the cells have a slight green tint, they are much more like the gray of sunglasses and automobile windows. " Wi
The vaccine is designed to mimic the coronavirus and train the immune system to react if a person is later infected Sign up for Guardian Australia's coronavirus email Download the free Guardian app to get the most important news notifications The vaccine developed and tested by a team at Oxford University is one of the most promising of the many candidates being developed around the world to prot
Most stars begin in binary systems, why not ours? Puzzles posed by the Oort cloud and the possibility of Planet 9 may be solved by a new theory of our sun's lost companion. The sun and its partner would have become separated long, long ago. If most stars form in binary pairs , what about our Sun? A new paper presents a model supporting the theory that the Sun may have started out as one member of
A drug normally used in rheumatoid arthritis and cancer treatments, tocilizumab, improves hospital survival in critically-ill patients admitted to the intensive care unit (ICU). The findings were published in The Lancet Rheumatology on Aug. 14, and Hackensack Meridian Health researchers have updated the U.S. Food and Drug Administration and other national leaders of the findings to potentially acc
When a weather station in Death Valley recorded a high of 130 degrees Sunday, it triggered an inquiry to verify the reading. Here's a look into the exacting process of vetting extreme weather claims. (Image credit: Mario Tama/Getty Images)
Butterflies, fish and frogs sport rear-end eyespots that reduce predation. Painting eye markings on cows similarly seems to ward off predators. — Read more on ScientificAmerican.com
Democrats turned over their convention keynote speech last night to a split-screen array of 17 diverse young leaders one day after news leaked that Republicans had invited to speak at their convention the white suburban couple who brandished guns at a multiracial group of Black Lives Matter protesters outside their St. Louis home in June. Even with all else that has happened during Donald Trump's
A team of mathematicians has finally finished off Keller's conjecture, but not by working it out themselves. Instead, they taught a fleet of computers to do it for them. Keller's conjecture, posed 90 years ago by Ott-Heinrich Keller, is a problem about covering spaces with identical tiles. It asserts that if you cover a two-dimensional space with two-dimensional square tiles, at least two of the
Bacteria that can help defuse highly toxic dioxin in sediments in the Passaic River—a Superfund hazardous waste site—could eventually aid cleanup efforts at other dioxin-contaminated sites around the world, according to Rutgers scientists.
Special metal oxides could one day replace semiconductor materials that are commonly used today in processors. Now, for the first time, an international team of researchers from Martin Luther University Halle-Wittenberg (MLU), the University of Kaiserslautern and the University of Fribourg in Switzerland was able to observe how electronic charge excitation changes electron spin in metal oxides in
Researchers for years have understood how attitudes held with certainty might predict behavior, but psychologists now suggest there may be a more general disposition at work that predicts the certainty of newly formed evaluations, just as they do for pre-existing opinions.
Using high-resolution data, researchers have created the first map of the causes of change in global mangrove habitats between 2000 and 2016 – a valuable tool to aid conservation efforts for these vital coastline defenders.
A new study shows how differentiation of a single gene changes behavior in a wild songbird, determining whether the white-throated sparrow displays more, or less, aggression.
Traditional ways of producing entanglements, necessary for the development of any 'quantum internet' linking quantum computers, are not very well suited for fiber optic telecoms networks used by today's non-quantum internet. However, researchers have come up with a new way to produce such particles that is much more compatible.
Documents reveal that the Secret Service used Locate X as part of a social media tracking package. The service "allows investigators to draw a digital fence around an address or area, pinpoint mobile devices that were within that area, and see where else those devices have traveled, going back months." Other agencies that have used this service include the Immigration and Customs Enforcement, the
Press F According to damning new research, only about 16 percent of the medical misinformation posted on Facebook gets caught by the social media giant's filters. The remaining 84 percent is never labeled as inaccurate, Business Insider reports . That means countless Facebook users are seeing potentially dangerous, misleading medical information without any sort of warning that it isn't accurate.
The majority of drug delivery systems use nano carriers to transport drugs due to their small size and ability to distribute drugs to otherwise inaccessible sites of the body. The downside to this small size, however, is that large quantities are needed to match the required dosage.
Researchers, who remotely videotaped a generation of wild chimpanzees learning to use tools, gain insights into how technology came to define human culture.
Marine pollutants are taken up by corals directly from seawater as well as through accumulation in their food, shows research from KAUST that uses a state-of-the-art spectroscopy technique known as cavity ring-down spectroscopy. This is the first time the approach has been used to measure pollutant accumulation.
PIM kinases are enzymes that promote metastatic growth and spread of cancer cells. Researchers from the University of Turku, Finland, have obtained new information on how PIM kinases enhance cancer cell motility by regulating the formation of actin fibers in the cytoskeleton. The published results support the development of PIM-targeted therapies to prevent metastasis formation in cancer patients.
Researchers, who remotely videotaped a generation of wild chimpanzees learning to use tools, gain insights into how technology came to define human culture.
Scientists from the ESRF, together with teams from CEA and CNRS/Sorbonne Université, have found the proof for a liquid-to-liquid transition in sulfur and of a new kind of critical point ending this transition. Their work is published in Nature.
The latest research from the University of Tennessee Institute of Agriculture indicates that the COVID-19 pandemic has affected all aspects of agricultural commodity production and distribution, leading to substantial price declines and reduced income for farmers.
A new study appearing in The American Journal of Medicine, published by Elsevier, calculates the lifetime risk of death from firearms and drug overdoses in the United States. The lifetime risk of death from firearms is about one percent, meaning that approximately one out of every 100 children will die from firearms if current death rates continue. The lifetime risk of death from drug overdoses is
Researchers used artificial intelligence and genetic analyses to examine the structure of the inner surface of the heart using 25 000 MRI scans. They found that the complex network of muscle fibres lining the inside of the heart, called trabeculae, allows blood to flow more efficiently and can influence the risk of heart failure. The study answers old questions in human physiology and leads to new
NASA JPL are developing autonomous capabilities that could allow future Mars rovers to go farther, faster and do more science. Training machine learning models on the Maverick2 supercomputer at the Texas Advanced Computing Center, their team developed and optimized models for Drive-By Science and Energy-Optimal Autonomous Navigation. The team presented results of their work at the IEEE Aerospace C
For some years now, Biomarin has been working on a gene therapy for hemophilia A. That's the form of the disease caused by a deficiency in Factor VIII, which is a necessary part of the blood-clotting cascade. Like many such conditions, it comes in a wide range of phenotypes. One group of patients (around 10%) makes a nonfunctional version of the protein, while the majority just make insufficient
Marine pollutants are taken up by corals directly from seawater as well as through accumulation in their food, shows research from KAUST that uses a state-of-the-art spectroscopy technique known as cavity ring-down spectroscopy. This is the first time the approach has been used to measure pollutant accumulation.
Dry soils in Germany, heat records in the Arctic and thawing permafrost soils in Siberia. The consequences of climate change are visible across the globe. To reduce the concentration of carbon dioxide (CO2) in the atmosphere, numerous research groups are investigating how CO2 can be used as a raw material for the production of chemicals.
PIM kinases are enzymes that promote metastatic growth and spread of cancer cells. Researchers from the University of Turku, Finland, have obtained new information on how PIM kinases enhance cancer cell motility by regulating the formation of actin fibers in the cytoskeleton. The published results support the development of PIM-targeted therapies to prevent metastasis formation in cancer patients.
Researchers at the University of Bern have developed the highly sensitive ORIGIN instrument, which can provide proof of the smallest amounts of traces of life, for future space missions. Space agencies such as NASA have already expressed interest in testing ORIGIN for future missions. The instrument may be used on missions to the ice moons of Europa (Jupiter) and Enceladus (Saturn), for example.
Demand for food is set to rise substantially in the coming decades, which raises a question: How well can the ocean fill the gap between current supply and future need?
Few people who have undergone nasopharyngeal swabs for coronavirus testing would describe it as a pleasant experience. The procedure involves sticking a long swab up the nose to collect a sample from the back of the nose and throat, which is then analyzed for SARS-CoV-2 RNA by the reverse-transcription polymerase chain reaction (RT-PCR). Now, researchers reporting in ACS Nano have developed a prot
Supermassive black holes, which likely reside at the centers of virtually all galaxies, are unimaginably dense, compact regions of space from which nothing—not even light—can escape. As such a black hole, weighing in at millions or billions of times the mass of the Sun, devours material, it is surrounded by a swirling disk of gas. When gas from this disk falls towards the black hole, it releases a
Companies are developing brain-machine interfaces that aim to connect humans to computers. One major challenge is finding materials that can accomplish this without damaging human tissue. At a recent event, a team of researchers presented a specialized version of a polymer that could someday make brain-machine interfaces safer and more effective. Elon Musk's Neuralink has a straightforward outloo
Special metal oxides could one day replace semiconductor materials that are commonly used today in processors. Now, for the first time, researchers were able to observe how electronic charge excitation changes electron spin in metal oxides in an ultrafast and inphase manner.
Trace vapor detection technologies are crucial for ensuring reliable and safe detection of explosives and illegal drugs. Researchers have developed a compact testing device called the Trace Vapor Generator for Explosives and Narcotics, which is portable and can be used for non-contact sampling of these vapors. The team reports the TV-Gen can accurately generate trace vapors of low vapor pressure c
Researchers have discovered the Hawaiian tiger cowrie is a voracious predator of sponges. Among preferred sponge prey is the invasive Orange Keyhole sponge (Mycale grandis).
The majority of drug delivery systems use nano carriers to transport drugs due to their small size and ability to distribute drugs to otherwise inaccessible sites of the body. The downside to this small size, however, is that large quantities are needed to match the required dosage.
Scientists have developed an RNA molecule that can be used in bone marrow cells to correct genetic errors that affect protein production. Patients suffering from a rare hereditary disease that causes a painful hypersensitivity to sunlight could benefit in future.
Unlike broadleaf trees, conifers are evergreen and retain their photosynthesis structure throughout the year. Especially in late winter, the combination of freezing temperatures and high light intensity exposes the needles to oxidative damage that could lead to the destruction of molecules and cell structures that contribute to photosynthesis. Researchers have discovered a previously unknown mecha
A group of theoretical physicists have proposed a 'table-top' device that could measure gravity waves. However, their actual aim is to answer one of the biggest questions in physics: is gravity a quantum phenomenon? The key element for the device is the quantum superposition of large objects.
New evidence may debunk the idea that Columbus brought syphilis to Europe. Europeans could already have been infected with this sexually transmitted disease before the 15th century, according to a new study. In addition, the researchers have discovered a hitherto unknown pathogen causing a related disease. The predecessor of syphilis and its related diseases could be over 2,500 years old. "It see
A handful of new studies suggest that people who had been infected with COVID-19 had "memory" T cells that were able to facilitate a unique immune response against subsequent exposure to the virus. "This calls for some optimism about herd immunity, and potentially a vaccine," Smita Iyer, an immunologist at the University of California, Davis told The New York Times. Still, many questions remain a
Unlike chimpanzees in East and West Africa, who use a single tool to extract termites, chimpanzees in Central Africa's Congo Basin use tool sets–puncturing sticks or perforating twigs plus fishing probes–to harvest the insects from underground nests or towering earthen mounds scattered across lowland forests.
The latest research from the University of Tennessee Institute of Agriculture indicates that during late April and early May 2020, approximately 525,000 Tennessee households were food insufficient, meaning they sometimes or often did not have enough to eat – that's one in 10 families. About 30% of these struggling households were food sufficient prior to the onset of the pandemic.
A University of Alberta researcher has found a treatment that increases the speed of nerve regeneration by three to five times, leading to much better outcomes for trauma surgery patients.
Demand for food is set to rise substantially in the coming decades, which raises a question: How well can the ocean fill the gap between current supply and future need?
Researchers for years have understood how attitudes held with certainty might predict behavior, but a series of new studies led by a University at Buffalo psychologist suggest there may be a more general disposition at work that predicts the certainty of newly formed evaluations, just as they do for pre-existing opinions.
An LSU Health New Orleans radiologist and evolutionary anatomist have teamed up to show the same techniques used for research on reptile and bird lungs can be used to help confirm the diagnosis of COVID-19 in patients. Their paper published in BMJ Case Reports demonstrates that 3D models are a strikingly clearer method for visually evaluating the distribution of COVID-19-related infection in the r
New research led by Dr. Jeff Biernaskie, PhD, has made an exciting leap forward in understanding how skin heals, which could lead to drug treatments to vastly improve wound healing. The study, published in the scientific journal Cell Stem Cell, was co-led by Dr. Sepideh Abbasi, PhD, Sarthak Sinha, MD/PhD candidate and Dr. Elodie Labit, PhD, postdoctoral fellow.
If you're making one of each kind of wipe, make sure you label them. You really don't want a 70% alcohol solution on your baby's skin. (Sandra Gutierrez G. /) Follow all of PopSci 's COVID-19 coverage here , including tips on cleaning groceries , ways to tell if your symptoms are just allergies , and a tutorial on making your own mask . Shortages have been a big side effect of the pandemic. They
Stream Full Episodes of Dodgeball Thunderdome: https://go.discovery.com/tv-shows/dodgeball-thunderdome/ Watch Dodgeball Thunderdome hosted by David Dobrik, Erin Lim, and Andrew "Hawk" Hawkins Wednesdays at 9P on Discovery. Dodgeball Thunderdome host David Dobrik challenges the Vlog Squad's Jonah, Suzy, Zane, and Mariah to compete against each other for $1,000. Enter for a chance to win $5,000 Dis
According to researchers at the University of Illinois, a supernova 65 light-years from Earth likely caused a mass extinction event during the Late Devonian period, 359 million years ago. The researchers found radioactive isotopes in rocks that may be able to confirm such an event, as detailed in a new paper published in the journal Proceedings of the National Academy of Sciences . During the Lat
Researchers used artificial intelligence and genetic analyses to examine the structure of the inner surface of the heart using 25,000 MRI scans. They found that the complex network of muscle fibers lining the inside of the heart, called trabeculae, allows blood to flow more efficiently and can influence the risk of heart failure. The study answers very old questions in basic human physiology and l
Researchers have reached an important milestone on the road to the particle accelerator of the future. For the first time, a laser plasma accelerator has run for more than a day while continuously producing electron beams. The LUX beamline achieved a run time of 30 hours.
Researchers create a centralized electronic medical records tool to gather, monitor, analyze clinical trends in COVID-19 across multiple countries. Proof-of-concept platform overcomes key hurdles of decentralized EMR systems.
In smaller spacecraft such as CubeSat satellites, a salt-based monopropellant is showing promise. It can be used both in high-thrust chemical propulsion for fast time-sensitive maneuvers, and electric mode for slow maneuvers, such as orbit maintenance. Now, researchers have more knowledge about how it performs under pressure to inform rocket design.
Nature, Published online: 19 August 2020; doi:10.1038/d41586-020-02448-5 A new way to shape aerogels opens up their use, and understanding how sulfur can change state between two liquids.
Few people who have undergone nasopharyngeal swabs for coronavirus testing would describe it as a pleasant experience. The procedure involves sticking a long swab up the nose to collect a sample from the back of the nose and throat, which is then analyzed for SARS-CoV-2 RNA by the reverse-transcription polymerase chain reaction (RT-PCR). Now, researchers reporting in ACS Nano have developed a prot
PIM kinases are enzymes that promote metastatic growth and spread of cancer cells. Researchers from the University of Turku, Finland, have obtained new information on how the PIM kinases enhance cancer cell motility by regulating the formation of actin fibres in the cytoskeleton. The published results support the development of PIM-targeted therapies to prevent metastasis formation in cancer patie
Researchers at the University of Bern have developed the highly sensitive ORIGIN instrument, which can provide proof of the smallest amounts of traces of life, for future space missions. Space agencies such as NASA have already expressed interest in testing ORIGIN for future missions. The instrument may be used on missions to the ice moons of Europa (Jupiter) and Enceladus (Saturn), for example.
New stud shows high levels of some cytokines seen in COVID-19 patients, as part of a cytokine storm, may prevent the development of long-term immunity to SARS-CoV-2.
Penn State research suggests the language young adults use to describe the effects they feel from drinking may give insight into their drinking habits.
A new study by researchers from the National Centre for Biological Sciences (NCBS), Bengaluru, published today in the Royal Society's journal Biology Letters, shows that dispersals, when undertaken by butterflies in search of unpredictable resources, selectively burden the egg-carrying females on their long flights.
Bacteria that can help defuse highly toxic dioxin in sediments in the Passaic River – a Superfund hazardous waste site – could eventually aid cleanup efforts at other dioxin-contaminated sites around the world, according to Rutgers scientists. Their research, published in the journal Environmental Science & Technology, needs further work to realize the full potential of the beneficial bottom-dwell
When it comes to brain cells, one size does not fit all. Neurons come in a wide variety of shapes, sizes, and contain different types of brain chemicals. A new study in Nature suggests that the identities of all the neurons in a worm are linked to unique members of a single gene family that control the process of converting DNA instructions into proteins, known as gene expression.
Scientists from the ESRF, together with teams from CEA and CNRS/Sorbonne Université, have found the proof for a liquid-to-liquid transition in sulfur and of a new kind of critical point ending this transition. Their work is published in Nature.
UC San Diego scientists using leading-edge technologies have produced the first visualizations of LRRK2, the elusive protein that many consider the key of fully understanding the causes of genetic Parkinson's disease, inside its natural cellular environment and the first high-resolution blueprint of the protein. They leveraged these depictions to describe how LRRK2 binds to cellular tracks called
A touch of gold – or another noble metal – can change the structure of a crystal and its intrinsic properties, physicists at the University of Warwick have demonstrated in a display of modern-day alchemy.
A team including Wei Liu, assistant professor in ASU's School of Molecular Sciences (SMS) and the Biodesign Institute's Center for Applied Structural Discovery, has published a paper today in Molecular Cell that offers promising details for improved therapeutic treatments for cardiac disease.
This observational study examined the association between state participation in Medicaid expansion through the Affordable Care Act and changes in the use of surgical care for common outpatient procedures.
Researchers used artificial intelligence and genetic analyses to examine the structure of the inner surface of the heart using 25,000 MRI scans. They found that the complex network of muscle fibers lining the inside of the heart, called trabeculae, allows blood to flow more efficiently and can influence the risk of heart failure. The study answers very old questions in basic human physiology and l
Salk Institute scientists have made a major advance in the pursuit of a safe and effective treatment for type 1 diabetes, an illness that impacts an estimated 1.6 million Americans with a cost of $14.4 billion annually. Using stem cell technology, Salk researchers generated the first human insulin-producing pancreatic cell clusters able to evade the immune system. These "immune shielded" cell clus
For decades, physicians have known that many kinds of cancer cells often spread first to lymph nodes before traveling to distant organs through the bloodstream. New research from Children's Medical Center Research Institute at UT Southwestern (CRI) provides insight into why this occurs, opening up new targets for treatments that could inhibit the spread of cancer.
Potenshöjande läkemedel av typen Viagra har potential att förbättra prognosen hos män med tjock- och ändtarmscancer. Dessa så kallade PDE5-hämmare tycks ha en cancerhämmande förmåga, enligt en studie från Lunds universitet och Region Skåne. En ny studie från Centrum för Primärvårdsforskning, ett samarbete mellan Lunds universitet och Region Skåne, visar att de potenshöjande läkemedlen fosfodieste
It's been several months since I wrote an update on my ongoing efforts to restore Deep Space Nine. I took a break from the project through much of June due to a move and an associated injury but jumped back into it in July and have been at work steadily since then. The majority have my time has been focused on understanding how shifting the episode into various alternative frame rates would impac
Nature, Published online: 19 August 2020; doi:10.1038/d41586-020-02382-6 A mutation in the C9orf72 gene is the most common genetic cause of two neurodegenerative diseases. A newly identified immunological function for the C9orf72 protein points to a potential therapeutic strategy for these diseases.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2592-2 Reconstitution of the activation of the MLH1–MLH3 endonuclease shows how crossovers are formed during meiosis.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2618-9 Each one of the complete set of 118 neuron classes in Caenorhabditis elegans can be specified individually by the expression of unique combinations of homeodomain proteins.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2624-y The PAT complex, an intermembrane chaperone complex comprising the ER-resident membrane proteins CCDC47 and Asterix, directly interacts with nascent transmembrane domains to facilitate the biogenesis of multi-spanning membrane proteins.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2603-3 Quantum error correction of Gottesman–Kitaev–Preskill code states is realized experimentally in a superconducting quantum device.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2631-z Metabolically-mature human islet-like organoids generated from induced pluripotent stem cells are able to recapitulate insulin-responsive pancreatic islet function and avoid immunologic cell death in diabetic mouse transplantation models.
Nature, Published online: 19 August 2020; doi:10.1038/d41586-020-02380-8 Diodes are devices that conduct electric current mainly in one direction. An electrically polar film that acts as a diode for superconducting current could lead to electronic devices that have ultralow power consumption.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2590-4 A superconducting diode that has zero resistance in only one direction is realized in an artificially engineered superlattice without inversion symmetry, enabling directional charge transport without energy loss.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2595-z Observations of a cold molecular gas associated with the atomic hydrogen outflow from the centre of our Galaxy indicate that this gas has a surprisingly high mass but unclear origin.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2635-8 A genome-wide association study shows that myocardial trabeculae are an important determinant of cardiac performance in the adult heart, identifies conserved pathways that regulate structural complexity and reveals the influence of trabeculae on the susceptibility to cardiovascular disease.
Nature, Published online: 19 August 2020; doi:10.1038/d41586-020-02383-5 A cellular condition called oxidative stress can kill cancer cells. The finding that skin cancer cells evade such destruction using lipids acquired while passing through lymphatic vessels reveals a mechanism that boosts cancer spread.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2593-1 Under high pressure, elemental sulfur shows a sharp density discontinuity that evolves with pressure and temperature and terminates at a critical point, indicating a first-order liquid–liquid phase transition.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2625-x Studies of mice and humans suggest a role for loss of the C9orf72 protein in some neurodegenerative disorders: with reduced C9orf72 levels, there is more inflammation mediated by the STING protein in immune and brain cells.
Nature, Published online: 19 August 2020; doi:10.1038/d41586-020-02381-7 A molecule produced by the metabolism of proteins and fats has been found to accumulate in the blood of older people, and to endow cancer cells with the ability to spread from one site in the body to others.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2591-3 Observed global-mean sea-level rise since 1900 is reconciled with estimates based on the contributing processes, revealing budget closure within uncertainties and showing ice-mass loss from glaciers as a dominant contributor.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2629-6 Single-cell RNA-sequencing analysis of embryogenesis and X chromosome inactivation in the opossum (Monodelphis domestica) resolves the developmental trajectory of a marsupial, and sheds light on the evolution of embryogenesis in mammals.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2630-0 Ageing in humans is associated with an increase in circulating methylmalonic acid, which induces expression of SOX4 and promotes tumour progression.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2616-y Modelled supply curves show that, with policy reform and technological innovation, the production of food from the sea may increase sustainably, perhaps supplying 25% of the increase in demand for meat products by 2050.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2636-7 Structural studies of the dimerization quality control E3 ubiquitin ligase SCF–FBXL17 indicate that its selectivity for aberrant complex formation is based on recognizing both shape and complementarity of interacting domains.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2594-0 A direct ink writing protocol for silica aerogels enables 3D printing of lightweight, miniaturized objects with complex shapes, with the possibility to easily add functionality by incorporating nanoparticles.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2623-z Melanoma cells undergo less oxidative stress and less ferroptosis in lymph than in blood, owing to higher levels of oleic acid in lymph, and thus exposure to the lymphatic environment increases subsequent metastasis through blood.
Nature, Published online: 19 August 2020; doi:10.1038/s41586-020-2602-4 A built-in electric field at the interface of metals and centrosymmetric semiconductors is shown to induce polar structures in the semiconductors and generate substantial piezoelectric and pyroelectric effects.
When talking to babies, humans slow down their speech, raise their pitch and change the "color" of their voice. This 'baby talk,' as people know it, increases the infant's attention and facilitates language learning. Among animals, mothers often engage in pup-directed vocalizations too, but does this also imply voice changes? A team of scientists that included Smithsonian Tropical Research Institu
Pioneering new research has highlighted some of the political difficulties with the UK's energy transition, in particular around vested fossil fuel interests.
As a typical representative of air plants, Tillandsia species can absorb moisture from the air with their leaves. Inspired by this hygroscopic foliage, Prof. Chen Tao's team at the Ningbo Institute of Materials Technology and Engineering (NIMTE) of the Chinese Academy of Sciences (CAS), has developed a new type of hygroscopic photothermal organogel (POG).
The giant pumice raft created by an underwater volcanic eruption last August in Tonga has begun arriving on the Australian eastern seaboard, delivering millions of reef-building organisms that researchers say could be a 'vitamin boost' for the Great Barrier Reef.
Unconventional monetary policy does not lead to greater risk-taking by banks, according to new research. This will be welcome news for central banks and policymakers as they ramp up efforts to limit the economic fallout of the pandemic.
Over the past two decades, a new area at the interface of semiconductor physics, electronics and quantum mechanics has been gaining popularity among theoretical physicists and experimenters. This new field is called spintronics, and one of its main tasks is to learn how to control the spin of charge carriers in well known semiconductor structures. Many theoretical efforts are always required befor
A team of researchers at DESY has reached an important milestone on the road to the particle accelerator of the future. For the first time, a so-called laser plasma accelerator has run for more than a day while continuously producing electron beams. The LUX beamline, jointly developed and operated by DESY and the University of Hamburg, achieved a run time of 30 hours. "This brings us a big step cl
When talking to babies, humans slow down their speech, raise their pitch and change the "color" of their voice. This 'baby talk,' as people know it, increases the infant's attention and facilitates language learning. Among animals, mothers often engage in pup-directed vocalizations too, but does this also imply voice changes? A team of scientists that included Smithsonian Tropical Research Institu
This year's Democratic convention is heavy on biography, light on history. Speaker after speaker has told the story of Joe Biden's personal life: his working-class roots, his family tragedies, his resilience. The message is that Biden cares about ordinary Americans because he sees their struggles as an echo of his own. What no speaker has done is put Biden's personal history in the context of Ame
Cancer cells become super-charged when exposed to methylmalonic acid, a chemical that builds up in older people's bodies. cancer-cell-illustration_cropped.jpg Image credits: SciePro/ Shutterstock Human Wednesday, August 19, 2020 – 11:00 Brian Owens, Contributor (Inside Science) — Many forms of cancer become more common and deadlier as we get older. There are several reasons behind this, includi
A touch of gold—or another noble metal—can change the structure of a crystal and its intrinsic properties, physicists at the University of Warwick have demonstrated in a display of modern-day alchemy.
Som de første i verden er kinesiske mobilproducent ZTE på vej med et kamera gemt under en OLED-skærm. Det betyder et farvel til den forhadte skærmudskæring.
New database of cell lines helps expand the current way of doing research — enabling the development of better therapies through the evaluation of the entire genomic signature.
Southeastern Tibet is a major area for transport of the Tibetan Plateau materials. Recently, researchers from University of Science and Technology of China obtained the high-resolution crust and upper mantle velocity structure of this area from ambient noise and surface wave tomography. The results reveal three major dynamic modes in southeastern Tibet: rigid extrusion of upper crustal material, c
In a scathing CNN interview Tuesday, Anderson Cooper absolutely eviscerated MyPillow creator Mike Lindell for pushing the compound oleandrin as a cure for COVID-19 — even though it's not backed by any sort of scientific evidence. Cooper begins the interview guns blazing, immediately questioning the credentials and motivations of Lindell, who is on President Trump's coronavirus task force and serv
Most stars begin in binary systems, why not ours? Puzzles posed by the Oort cloud and the possibility of Planet 9 may be solved by the new theory. The sun and its partner would have become separated long, long ago. If most stars form in binary pairs , what about our Sun? A new paper presents a model supporting the theory that the Sun may have started out as one member of a temporary binary system
Refugees fleeing persecution endure unimaginable hardships in search of a better life. Physician Joseph Shin explains the essential collaboration of doctors and lawyers working together to help asylum seekers in the United States, sharing promising pathways toward securing the human dignities they deserve.
Pioneering new research has highlighted some of the political difficulties with the UK's energy transition, in particular around vested fossil fuel interests.
The mechanism behind salt-intake and hypertension has been elucidated for the first time, through vascular non-canonical Wnt5a/RhoA under Klotho deficiency.
With implementation of conservative treatment methods like physiotherapy and individually tailored, adjusted exercises, quality of osteoarthritis care can improve and patients can delay the need for an artificial hip or knee joint. This has been demonstrated by a clinical study from Norway that was recently presented at the European League Against Rheumatism (EULAR 2020) Online Annual Congress.
The giant pumice raft created by an underwater volcanic eruption last August in Tonga has begun arriving on the Australian eastern seaboard, delivering millions of reef-building organisms that researchers say could be a "vitamin boost" for the Great Barrier Reef.
Covid-19 patients with hypoxia respond positively to icatibant treatment, Radboud university medical center researchers wrote in JAMA Network Open. These findings have led to a follow-up study at ten Dutch hospitals into a drug that may be even more effective. The current study has been funded by ZonMw.
Despite one foraging trip landing him in hospital, the avant garde composer held a lifelong passion for mycology, using his expertise to supply New York restaurants – and surprise Italian quiz show audiences In February 1959, while on a visit to fellow composer Luciano Berio in Milan, John Cage appeared five times on a popular Italian television quiz show called Lascia o Raddoppia? (Double or Not
It's almost as though US universities have been living under a rock for the last six months. Sure, they're limiting in-person classes and telling students to stay quarantined inside their dorms — but, at the same time, many are welcoming students back to campus. Unsurprisingly, countless clusters of new coronavirus cases are cropping up at institutes of higher learning across the entire country.
New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma, researchers report. Suppressing the OSMR gene can improve the effectiveness of radiation therapy, according to their new study. "To improve patient response to glioblastoma treatment, we must find new vulnerabilities in cancer stem cells and overco
The Covid-19 pandemic has brought about rapid innovation in mental health care, and the move to telemedicine is likely here to stay to at least some degree, but new research led by UCL and King's College London cautions that serious barriers still need to be overcome.
The release of massive amounts of proteins called cytokines can lead to some of the most severe symptoms of COVID-19. An August 19 study in the journal Cell now suggests that high levels of some cytokines may also prevent people who are infected from developing long-term immunity as affected patients were observed to make very few of the type of B cells needed to develop a durable immune response.
The team is led by Associate Professor Ayrat Kayumov (Department of Genetics, Kazan Federal University). In this research, the scientists not only performed genome sequencing, but also found a completely new type of PII-Like Protein PotN.
Over the past two decades, a new area at the interface of semiconductor physics, electronics and quantum mechanics has been gaining popularity among theoretical physicists and experimenters. This new field is called spintronics, and one of its main tasks is to learn how to control the spin of charge carriers in well known semiconductor structures.
A team of researchers at DESY has reached an important milestone on the road to the particle accelerator of the future. For the first time, a laser plasma accelerator has run for more than a day while continuously producing electron beams. The LUX beamline, jointly developed and operated by DESY and the University of Hamburg, achieved a run time of 30 hours. The scientists are reporting on their r
New research looking at voters' perception of gender and aspiration suggests that voters do not penalize ambitious women candidates seeking political office, contrary to popular belief.
Rising temperatures due to our greenhouse gas emissions can cause greater damages to our economies than previous research suggested, a new study shows. Scientists from the Potsdam Institute for Climate Impact Research (PIK) and the Mercator Research Institute for Global Commons and Climate Change (MCC) took a closer look at what climate change does to regions at the sub-national level, such as US
Capacitors that rapidly store and release electric energy are key components in modern electronics and power systems. However, the most commonly used ones have low energy densities compared to other storage systems like batteries or fuel cells, which in turn cannot discharge and recharge rapidly without sustaining damage.
When computers share information with one another, the information gets encoded into bits, then decoded back into its original form. In the process, pieces of the information sometimes get scrambled, or lost. As a simplified example, an improperly decoded email that says "I am now sending you the money" could arrive at its destination saying "I am not sending you the money."
Light is known to have a number of fundamental properties, including color, brightness, and direction, most of which are immediately apparent and can be observed with the naked eye. There are now several instruments to detect and measure these properties, such as photon counters, detectors often used in research that measure brightness by counting individual light quanta. Crucially, some existing
The UN population forecast predicts that by 2050 there will be almost 10 billion people on the planet. They'll live mostly in cities and have an older median age than the current global population. One looming questions is, what will they eat? The Green Revolution of the 1960s used selective breeding to double crop yields of rice and wheat in some areas of the world, rescuing millions of people f
A new study into voter behaviour in the US and UK argues that electorates value aspiration and ambition among female candidates seeking office challenging common assumptions.
A European research alliance headed by the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn tracks the onset of ataxias. The results published in "The Lancet Neurology" provide valuable data for prevention studies. The data were collected by a research network, which includes scientific institutions from Austria, France, Germany, Hungary, Italy, Poland and Spain.
Rising temperatures due to our greenhouse gas emissions can cause greater damages to our economies than previous research suggested, a new study shows. Scientists from the Potsdam Institute for Climate Impact Research (PIK) and the Mercator Research Institute for Global Commons and Climate Change (MCC) took a closer look at what climate change does to regions at the sub-national level, such as US
Special metal oxides could one day replace semiconductor materials that are commonly used today in processors. Now, for the first time, an international team of researchers from Martin Luther University Halle-Wittenberg (MLU), the University of Kaiserslautern and the University of Fribourg in Switzerland was able to observe how electronic charge excitation changes electron spin in metal oxides in
Traditional ways of producing entanglements, necessary for the development of any 'quantum internet' linking quantum computers, are not very well suited for fiber optic telecoms networks used by today's non-quantum internet. However, researchers have come up with a new way to produce such particles that is much more compatible.
This F-16 in Florida is being flown by a real human. (US Air Force / Tech. Sgt. John Raven/) Fighter jets need humans to fly them, but someday, that could change. This week, the Defense Advanced Research Project Agency—better known as DARPA—is hosting a virtual Top Gun -style competition in which various artificial intelligence algorithms fly simulated jets in digital dogfights. No actual planes
Accountability, demilitarization and the transfer of responsibilities to social workers are needed to remake our overly antagonistic law-enforcement agencies — Read more on ScientificAmerican.com
If you were to stack up all the electronic waste produced annually around the world it would weigh as much as all the commercial aircrafts ever produced, or 5,000 Eiffel towers. This is a growing "tsunami" according to the UN, and it's fed by all the phones, tablets and other electronic devices that are thrown away each day.
With COVID-19 cases and deaths rising in the U.S. and globally, identifying new therapies to prevent and combat the virus is a top priority. Natural products from plants are an attractive option in the search for a cure. Approximately 374,000 plant species are on Earth; humans have used more than 28,000 of them as a form of medicine.
With COVID-19 cases and deaths rising in the U.S. and globally, identifying new therapies to prevent and combat the virus is a top priority. Natural products from plants are an attractive option in the search for a cure. Approximately 374,000 plant species are on Earth; humans have used more than 28,000 of them as a form of medicine.
With fertility rates falling as first-time parents get older, and the costs of treatments out of reach, a steady stream of Americans with perfectly good health insurance are traveling to countries they otherwise might never have set foot in to pursue a fundamental part of life: starting a family.
You live in a crowded underground city with everyone you know. A relative comes home, and you can tell that they've been exposed to something that could get you all sick. Unchecked, a disease could wipe out your whole civilization. So you do what needs to be done.
Comfortable strain gages can be directly placed on human skin to monitor continuous motion activity with widespread applications in robotics, human motion detection, and personal health care. However, it is challenging to develop an on-skin strain gage to monitor long-term human body motions without disturbing the natural movement of skin. In a new report now on Science Advances, Yan Wang, and a t
You live in a crowded underground city with everyone you know. A relative comes home, and you can tell that they've been exposed to something that could get you all sick. Unchecked, a disease could wipe out your whole civilization. So you do what needs to be done.
Rereading the Mueller report more than a year after its publication is an exercise in disappointment. One gets the feeling that Robert Mueller didn't press his inquiry to its end. Instead of settling the questions that haunt the 2016 campaign, he left them dangling, publishing a stilted document riddled with insinuation and lacunae. He rushed his work, closing up shop before finishing his assignm
In K-12 music classes and performances may look different this fall, but creativity and music-making technology will mean classes won't be silenced, one expert says. "There are so many online tools out there that music educators can use to bring students together during the COVID-19 pandemic," says Christopher Cayari, assistant professor of music education in the Patti and Rusty Rueff School of D
A research group elucidated the brain circuit mechanism that cause of spatial memory impairment in Alzheimer's disease.In the future, improving brain remapping function may reverse spatial memory impairment in patients with Alzheimer's disease.
Researchers at Berkeley Lab and UC Berkeley have demonstrated that a common material can be processed into a top-performing energy storage material. Their discovery could improve the efficiency, reliability, and robustness of personal electronics, wearable technologies, and car audio systems.
Through their basic research, physicians at the Heart Center of the University Hospital Bonn have discovered how the communication between individual cells can be influenced with the help of a specific protein. These findings are an important approach to improving the treatment of diseases such as arteriosclerosis (calcified blood vessels), which causes heart attacks. The study was published onlin
Social adversity in early childhood appears to be a significant risk factor for death in early adulthood. Children who have experienced repeated serious adversity such as losing a parent, mental illness in the family, poverty or being placed in foster care have a 4.5 times higher risk of dying in early adulthood than children who have not experienced adversity during childhood. This is the conclus
With the global COVID-19 pandemic shifting more and more of our work and school online, virtual communities are more important than ever — but how do we know, without bias, that our online groups are actually successful in helping us with our goals? A team of researchers based in Italy think has proposed the first objective metric to assess the effectiveness of virtual groups.
City of Hope and TGen have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on FDA-approved immunotherapy regimens. A potential takeaway: Oncologists might encourage patients to eat a high-fiber diet, including fruits and vegetables high in fructo-oligosaccharides such as bananas, dried fruit, onions, leeks, garlic, a
ESA astronaut Alexander Gerst during his 2018 stay on the International Space Station, with two floating SPHERES robots tethered to a container of liquid, serving to simulate the experience of pulling a derelict satellite out of orbit.
All-inorganic zero-dimensional (0D) metal halides are widely applied in the fields of display and solid-state lighting due to their excellent photoluminescence (PL) properties and high stability.
Heavy monsoon rains lashed New Delhi Wednesday, inundating roads and piling on misery for commuters in the chaotic Indian capital, as the death toll from the annual deluge across South Asia rose to nearly 1,300.
Many colleges are welcoming students back for in-person learning and dormitory living this fall semester. Looming over everything: Campuses could shut back down at any time.
Unconventional monetary policy does not lead to greater risk-taking by banks, according to new research. This will be welcome news for policymakers and central banks as they ramp up efforts to limit the economic fallout of the pandemic.
Leading coma experts have created an ambitious plan to help doctors better care for comatose patients and answer that most awful question: 'Will my loved one wake up?'
When addressing infants, human adults tend to change the speed, pitch and "color" of their voice. This "baby talk" is known to facilitate language learning. According to new research at the Smithsonian Tropical Research Institute, it may not be exclusive of humans. Some bats have their own version of "baby talk" to communicate with their pups.
Australian researchers have discovered that removing copper from the blood can destroy some of the deadliest cancers that are resistant to immunotherapy using models of the disease.
UNSW researchers have found their previous discovery of bacteria living on air in Antarctica is likely a process that occurs globally, further supporting the potential existence of microbial life on alien planets.
In infectious disease outbreaks, digital contact tracing alone could reduce the number of cases, but not as much as manual contract tracing, new University of Otago-led research published in the Cochrane Library reveals.
Nature, Published online: 19 August 2020; doi:10.1038/d41586-020-02414-1 In the first of a series of editorials, we look back at some of the key findings from scientists' race to demystify SARS-CoV-2.
Wellbeing and decision-making during recovery from disasters such as Australia's summer bushfires and the coronavirus (COVID-19) pandemic are supported by a new researched-backed resource.
Using NASA's Kepler spacecraft, astronomers have detected a new bright transient event. After further analysis, the newly found transient source turned out to be a cataclysmic variable (CV) star. The finding is detailed in a paper published August 10 on the arXiv pre-print server.
The prevalence of intimate partner violence has been the hidden and often unspoken impact of the COVID-19 pandemic, researchers report. Many of the strategies critical to ensuring public health, such as lockdowns, stay-at-home orders, social isolation, and social distancing, have a profound impact on families experiencing intimate partner violence, also known as IPV, according to a new paper in P
Government health leaders including Dr. Francis S. Collins and Dr. Anthony S. Fauci urged caution last week, citing weak data from the country's largest plasma study.
UNSW researchers have found their previous discovery of bacteria living on air in Antarctica is likely a process that occurs globally, further supporting the potential existence of microbial life on alien planets.
Displaying family photos in the workplace cuts down on employee fraud and other unethical behavior, new Washington University in St. Louis research finds.
Some of the cringiest articles in Scientific American's history reveal bigger questions about scientific authority — Read more on ScientificAmerican.com
Editor in chief Nicholas Thompson sits down with WIRED reporters to talk about how another round of remote learning could deepen education inequality in the US.
For Asiatic lionesses, sex may be a way of protecting their cubs from murderous males. lions-top-image_cropped.jpg An Asiatic lioness and her cubs. Image credits: Milan Zygmunt/ Shutterstock Creature Wednesday, August 19, 2020 – 09:00 Nala Rogers, Staff Writer (Inside Science) — On a bright day in 2015, an Asiatic lioness hid her cubs in a thicket and went to meet two strangers. The strange mal
Tasty treat for a healthy life. (Kelly Sikkema via Unsplash/) Protein shakes are not just used by serious athletes and bodybuilders. They are quick and easy additions to your diet and can replace meals packed with protein, vitamins, and probiotics—or they can act as a supplement for after your workout to help your muscles recover and strengthen. For meals on the go you can buy your shakes pre-mix
In a letter to James AH Murray in 1879, the writer ME Lewes wrote "I wish always to be quoted as George Eliot." She perhaps would not have been pleased by a new campaign from The Women's Prize for Fiction and its sponsor, Baileys called Reclaim Her Name campaign.
A German icebreaker carrying scientists on a year-long international expedition in the high Arctic has reached the North Pole, after making an unplanned detour because of lighter-than-usual sea ice conditions.
Work or play with minimal interruption. (ConvertKit via Unsplash/) Dependable WiFi access is crucial when working or unwinding at home. If your signal constantly drops when presenting in meetings or leaves you with unexpected cliffhangers watching shows, you can expand the coverage area of your WiFi network with an extender. Improve the strength and range of your connection with these affordable
Now you just need a podcast idea. ( Jonathan Farber via Unsplash/) It seems like someone starts a podcast every day. And that's because they do. Podcasts are fairly simple to start but challenging to maintain at a high quality. If you sound like you are recording in the closet on an iPhone 6 people probably won't hang around for your witty banter. Start on the right foot with a decent mixer/recor
Sheltering under translucent quartz stones shields the moss from heat, cold, drought and intense ultraviolet rays A small moss growing in the Mojave desert in California uses a remarkable protection from the desert sun – it shelters under translucent quartz stones. It is a miniature greenhouse that shields the moss from heat, cold, drought and intense ultraviolet rays. The desert gets extremely h
Kamala Harris' candidacy as vice president of the United States provoked familiar criticism, based in part on her identity as a woman. Critics find her too angry, too confident, too competitive. But when women do act less competitively, they are seen as less capable of leadership. This is the "double-bind" women face when aspiring to leadership positions.
The bushfire royal commission is examining ways Indigenous land and fire management could improve Australia's resilience to national disasters. On the face of it, this offers an opportunity to embrace Indigenous ways of knowing.
DNA is not only the blueprint of life, it has become the backbone for making tiny structures that can be inserted into the human body to diagnose and treat disease. In particular, researchers are setting their sights on a technique known as DNA origami, in which they meticulously assemble hundreds of strands of DNA to build a Lilliputian collection of structures that could include drug delivery co
Two EPFL students have compared the ability of a forest in Vaud Canton to protect against avalanches before and after it was ravaged by fire in 2018. Their method could be applied to other forested slopes, helping to enhance local reforestation strategies.
Croplands are a valuable, yet scarce natural resource. To guard against serious and potentially irreversible environmental harm, croplands should not extend beyond 15% of the earth's ice-free surface.
When a massive star reaches the end of its life, it can explode in a process known as a supernova. The massive star—much more massive than our sun—runs out of fuel in its core. Gravity forces the core to collapse on itself, causing a shockwave to form and spew stellar material into space. Metals, along with heavy elements such as carbon, are expelled into the universe.
On the surface, the humble melon may just look like a tasty treat to most. But researchers from Japan have found that this fruit has hidden depths: retrotransposons (sometimes called "jumping sequences") may change how genes are expressed.
For decades, greater than 60% of the human genome was believed to be "junk DNA" that served little or no purpose in the course of human development. Recent research by Colorado State University is challenging this notion to show that junk DNA might be important after all.
Although tiger sharks have a reputation as swift and fierce predators, new research by The University of Western Australia, Australian Institute of Marine Science and Murdoch University has revealed that they actually prefer life in the slow lane.
Achieving pregnancy has been shown to be more likely between partners who carry dissimilar human leucocyte antigen (HLA) immune genes. Accordingly, humans are expected to choose HLA dissimilar reproductive partners. Earlier studies have demonstrated that HLA dissimilarity preferences are mediated either by body odors or facial preferences. However, it has been unclear whether HLA-based mating pref
Bluefin tuna, swordfish and Atlantic mackerel are among the fish species considered commercially extinct or extirpated on the Turkish side of the Marmara and Black Seas.
DNA is not only the blueprint of life, it has become the backbone for making tiny structures that can be inserted into the human body to diagnose and treat disease. In particular, researchers are setting their sights on a technique known as DNA origami, in which they meticulously assemble hundreds of strands of DNA to build a Lilliputian collection of structures that could include drug delivery co
Not just metals, hierarchical societies and fortified settlements: a new food also influenced economic transformations in the Bronze Age around 3,500 years ago. This is evidenced by frequent archeological discoveries of remains of broomcorn millet (Panicum miliaceum L.), a cereal with small, roundish grains. A major study by the Collaborative Research Center 1266 at Kiel University (CAU) was publi
On the surface, the humble melon may just look like a tasty treat to most. But researchers from Japan have found that this fruit has hidden depths: retrotransposons (sometimes called "jumping sequences") may change how genes are expressed.
For decades, greater than 60% of the human genome was believed to be "junk DNA" that served little or no purpose in the course of human development. Recent research by Colorado State University is challenging this notion to show that junk DNA might be important after all.
Black women with natural hairstyles, such as curly afros, braids, or twists, are often perceived as less professional than Black women with straightened hair, new research suggests. This is particularly true in industries where norms dictate a more conservative appearance, according to the study. The findings offer empirical evidence that societal bias against natural Black hairstyles infiltrates
Light-emitting diodes, or LEDs, are nearly ubiquitous in modern life, providing the brightness in phone displays, televisions, and lights. A new form of LEDs, made of a class of materials called halide perovskites, promises higher color quality and ease of manufacture, but has been known to fail when subjected to the kind of electrical current typically needed for practical uses. Now, Barry Rand,
Although tiger sharks have a reputation as swift and fierce predators, new research by The University of Western Australia, Australian Institute of Marine Science and Murdoch University has revealed that they actually prefer life in the slow lane.
Achieving pregnancy has been shown to be more likely between partners who carry dissimilar human leucocyte antigen (HLA) immune genes. Accordingly, humans are expected to choose HLA dissimilar reproductive partners. Earlier studies have demonstrated that HLA dissimilarity preferences are mediated either by body odors or facial preferences. However, it has been unclear whether HLA-based mating pref
On August 16, the Zwicky Transient Facility (ZTF), a robotic survey camera located at Palomar Observatory near San Diego, spotted an asteroid that had, just hours earlier, traveled only 1,830 miles (2,950 kilometers) above Earth's surface. Designated 2020 QG, it is the closest known asteroid to fly by Earth without impacting the planet. The previous known record-holder is asteroid 2011 CQ1, discov
On August 10, 2020, JAXA was informed that the Authorization of Return of Overseas-Launched Space Object (AROLSO) for the re-entry capsule from Hayabusa2 was issued by the Australian Government. The date of the issuance is August 6, 2020.
Bluefin tuna, swordfish and Atlantic mackerel are among the fish species considered commercially extinct or extirpated on the Turkish side of the Marmara and Black Seas.
The Korea Institute of Science and Technology (KIST) has made an announcement about the technology to extract high-purity hydrogen from ammonia and generate electric power in conjunction with a fuel cell developed by a team led by Young Suk Jo and Chang Won Yoon from the Center for Hydrogen and Fuel Cell Research. This confirms the possibility of using ammonia as a hydrogen carrier to transport la
While some options eliminate COVID-19 concerns, they still may be worrisome for other reasons. (Julia M Cameron from Pexels/) Follow all of PopSci 's COVID-19 coverage here , including breakdowns of the safest swimming options , safest dining options , and a tutorial on safest long-distance travel options . School is back in session for many students across the country, which means tough decision
Covid patients are reporting persistent, long-term symptoms of chronic fatigue. Let's get to the bottom of this "Long-haulers" is no longer just a job description for truckers. This term now refers to the growing number of people who contracted Covid-19 and have continued to have symptoms for more than 100 days – even though tests reveal no virus left in the body. Covid-19 "long-haulers" continue
Nature, Published online: 19 August 2020; doi:10.1038/d41586-020-02433-y President Jair Bolsonaro has threatened deep cuts to research budgets — now scientists hope legislation will give them protected funds.
A few young patients also develop strange inflammatory symptoms. A CDC report sheds light on how widespread this syndrome is, and what it could mean for vaccines.
Thousands protest in the UK after a formula replaced a test that influences college placement. It's led to broader scrutiny of automation and inequality.
Editor's Note: Every Wednesday, James Hamblin takes questions from readers about health-related curiosities, concerns, and obsessions. Have one? Email him at paging.dr.hamblin@theatlantic.com . Dear Dr. Hamblin, I'm a healthy 72-year-old living in Berkeley, California. My daughter, son-in-law, and grandkids recently moved here across the country, and now we have a bubble together. I offered to he
An old house. Sleepaway camp. The woods outside Burkittsville, Maryland . Every generation has its dark places, settings where horror filmmakers stage the zeitgeist's fears. During a pandemic, just about any spot where people congregate will do. But the new film Host takes an unexpected approach. The director Rob Savage sets his movie in a familiar virtual zone—a Zoom session—flipping the script
Tiden er kommet til at tage kampen for den gode hverdag med krav om arbejdsforhold på de offentlige arbejdspladser, som gør det muligt at være med, til man fylder 75.
We need a global debate on the best way to respond to these demographic changes. Photo illustration by Arthimedes / Shutterstock In their 1968 book The Population Bomb , biologists Paul Ehrlich and his wife Anne foretold a Malthusian future of famine and disease if humanity failed to control its growth. The Ehrlichs' warning made sense. At the time, the global population sat at about 3.5 billion,
Skogens eget metoo-upprop #slutavverkat och ett öppet brev från kvinnliga studenter i jägmästarprogrammet 2018 gjorde det tydligt att sexuella trakasserier är en del av kulturen vid skogsutbildningen. Forskare vid SLU har undersökt vad som hänt på utbildningen efter uppropet. En ny studie visar att både ledning, lärare och studenter alltför ofta avstått från att agera vid sexuella trakasserier so
The news: Pages spreading health misinformation got an estimated 3.8 billion views on Facebook this year as of May, according to analysis by human rights group Avaaz . Views peaked at nearly half a billion in April 2020 alone, just as the pandemic was rapidly escalating globally, it found. Content from 10 websites spreading health misinformation received almost four times as many estimated views
Att vara socialt aktiv ökar generellt chansen till god nattsömn. Men om du är aktiv sent på kvällen ger det kortad sömn – och kan därmed även påverka ditt sociala liv. Sömnighet påverkar kognitiv förmåga, motivation och beteende. Fler och fler lider av sömnstörningar, men effekterna av sömnighet på sociala interaktioner, som spelar en viktig roll för hälsa och välbefinnande, har varit rätt okända
The new book Adverse Events by Jill Fisher shows the reality behind phase 1 clinical trials in USA and the "healthy volunteers" who participate in those. Clue: they are not White middle-class university students with a penchant for altruism.
Shalev Hulio wants to explain himself. Normally, silence and secrecy are inherent in the spy business. For nine full years, Hulio never talked publicly about his billion-dollar hacking company—even when his hacking tools were linked to scandal or he was accused of being complicit in human rights abuses around the world. Lately, though, he's speaking up. "People don't understand how intelligence w
Until the beginning of August, Vietnam, population 97 million, was the world's largest country with zero coronavirus deaths. A small number of people have died since then. The one- party state implemented aggressive quarantines. It also funneled most of its coronavirus patients into one central hospital in Saigon. 25 Covid deaths as of August 19, 2020. Source: WHO Dashboard It was in December 201
Sweden's controversial, less-stringent lockdown has made an unlikely star of its state epidemiologist. He told us why he still believes in the national strategy and why he thinks a classic second wave is unlikely. Proportionately, Sweden has suffered many more deaths than its neighbors. Norway has had 48 coronavirus deaths per million people, Finland 60, Denmark 107, and Sweden 573. It's strange
Uruguay has been a rare bright spot in coronavirus-ravaged South America, thanks to a highly developed research infrastructure, a tradition of at-home medical care, and a strong public health system. Two key advisors to the government's pandemic response team explain how they scaled up their tests so fast and why they are now encouraging people to go outside more. The first cases in Uruguay were
Covid-19 was the second pandemic of the decade for Liberia, which was devastated by Ebola just five years ago. A US-trained public health officer who served in both emergencies explains how some institutional knowledge was carried over, as well as how the virus entered the country despite considerable precautions. The moment we heard that there was this new disease in China, we knew there was no
The government-run Robert Koch Institute for public health research in Berlin has been at the forefront of the country's robust pandemic response, leading the search for a vaccine and racing to push out vast stocks of tests. A career epidemiologist at the institute explains the challenges of reopening, communicating risk, and contact tracing in the German context. 9,232 Covid deaths as of August
For many years, Latin America's largest democracy was a leader on data governance. In 1995, it created the Brazilian Internet Steering Committee , a multi-stakeholder body to help the country set principles for internet governance. In 2014, impelled by Edward Snowden's revelations about surveillance by the US National Security Agency of countries including Brazil, Dilma Rousseff's government pion
Maâti Monjib speaks slowly, like a man who knows he's being listened to. It's the day of his 58th birthday when we speak, but there's little celebration in his voice. "The surveillance is hellish," Monjib tells me. "It is really difficult. It controls everything I do in my life." A history professor at the University of Mohammed V in Rabat, Morocco, Monjib vividly remembers the day in 2017 when h
China doesn't only collect enormous amounts of data on its own citizens: it also sucks up data from around the world that might one day be useful for its national security, using both domestic and foreign companies as conduits. Samantha Hoffman of the Australian Strategy Policy Institute, one of the leading experts on the Chinese surveillance state, shed light on this phenomenon last year with a
Late in the summer of 2016, Xu Yuyu received a call that promised to change her life. Her college entrance examination scores, she was told, had won her admission to the English department of the Nanjing University of Posts and Telecommunications. Xu lived in the city of Linyi in Shandong, a coastal province in China, southeast of Beijing. She came from a poor family, singularly reliant on her fa
Since the pandemic's beginning, scientists have argued over how respiratory viruses can spread. Now an experiment with guinea pigs and influenza is adding a new wrinkle.
You should never invest without fully understanding the risks, but tax prep and stock trading services often obfuscate the things you really need to know.
A heart journal has issued an expression of concern about a 2017 paper which looks suspiciously like a 2016 article by some of the same researchers that appeared in an anesthesiology publication. The 2017 paper, "Efficacy of prophylactic dexmedetomidine in preventing postoperative junctional ectopic tachycardia after pediatric cardiac surgery," was written by a group led … Continue reading
Editor's Note: Editor's Note: The Atlantic is making vital coverage of the coronavirus available to all readers. Find the collection here . Lauren Nichols has been sick with COVID-19 since March 10, shortly before Tom Hanks announced his diagnosis and the NBA temporarily canceled its season. She has lived through one month of hand tremors, three of fever, and four of night sweats. When we spoke o
America is seeing only the beginning of the attacks that Kamala Harris will face. Voters will expect her to be supportive of Joe Biden, of course, but they will inevitably find her insufficiently loyal and deferential. They will dismiss her as angry , cold, and schoolmarmish. They will hear her voice as shrill and grating . They will call her inauthentic, a liar, and a phony. Many people will wan
Nature, Published online: 19 August 2020; doi:10.1038/d41586-020-02418-x Paratek Pharmaceuticals successfully brought a new antibiotic to the market. So why is the company's long-term survival in question?
The size of salmon returning to rivers in Alaska has declined dramatically over the past 60 years because they are spending fewer years at sea, according to a new study led by researchers at the University of California, Santa Cruz, and the University of Alaska Fairbanks.
The size of salmon returning to rivers in Alaska has declined dramatically over the past 60 years because they are spending fewer years at sea, according to a new study led by researchers at the University of California, Santa Cruz, and the University of Alaska Fairbanks.
Kommunerne kan forbedre deres tilbud om rehabilitering og genoptræning, hvis de blev enige om, hvordan de skal måle effekten af tilbuddene, mener sundhedsøkonom.
R obert Gibbs had just woken up when his boss called. It was about 6 a.m., and Barack Obama, who was not normally a morning person, had written yet another draft of his keynote speech for the 2004 Democratic National Convention. Obama wanted to know what Gibbs, who had recently joined his campaign for the U.S. Senate, thought. After sheepishly admitting that he had not read his boss's latest effo
With former Vice President Joe Biden leading in the polls and Democratic control of the Senate possible, the United States may soon have the chance, for the first time in more than a decade, to enact urgently needed legislation to address global climate change—but only if Democrats don't repeat the mistakes they made at the start of the Obama administration. In June 2009, the House of Representat
Den internationale Bluetooth-organisation arbejder på at gøre wearables til en del af den digitale smitteopsporing. Den første udgave forventes at lande i løbet af få måneder.
DTU's fødevareinstitut har fundet pesticidrester i kontrollen for årets 1. kvartal. Tre fødevarer udgør en decideret sundhedsmæssig risiko, mens prøverne for fire andre ikke kan udelukkes.
Flöden av metan från insjöar är lägre nattetid än dagtid. De nordliga sjöarnas bidrag till de globala metanutsläppen därmed är 15 procent lägre än man tidigare trott. Det visar mätningar gjorda av forskare i Linköping. Sötvattensjöar, åar och dammar är den näst största källan till utsläpp av metan, en av de växthusgaser som har störst påverkan på den globala uppvärmningen. Metan är också den växt
South Africa's efforts to contain the virus are tainted by corruption. Top U.S. health officials intervened just as the F.D.A. was prepared to issue an emergency authorization for plasma as a virus treatment.
Researchers create a centralized electronic medical records tool to gather, monitor, analyze clinical trends in COVID-19 across multiple countries. Proof-of-concept platform overcomes key hurdles of decentralized EMR systems.
The size of salmon returning to rivers in Alaska has declined dramatically over the past 60 years because they are spending fewer years at sea, scientists report. Salmon are critically important to both people and ecosystems in Alaska, supporting commercial and subsistence fisheries and transporting nutrients from the ocean to inland areas. Smaller salmon provide less food for people who depend on
For children with Kawasaki disease with higher risk of developing blood vessel complications, adding corticosteroids to standard intravenous immunoglobulin treatment could boost initial treatment response and prevent complications.Researchers used real-world data from large, nationwide Japanese Kawasaki disease surveys to compare combination therapy with the standard treatment.
En genetisk studie av små förkalkningar som hittades i lungorna på lundabiskopen Peder Winstrups mumie visar att sjukdomen tuberkulos inte är äldre än cirka 6000 år och inte 70 000 år som tidigare antagits. Den extremt välbevarade arvsmassan från tuberkulosbakterien berättar att människan inte drabbades av tuberkulos innan hon blev jordbrukare. Tuberkulos är den bakteriella sjukdom som skördat fl
Nature Communications, Published online: 19 August 2020; doi:10.1038/s41467-020-17726-z The average body size of salmon has declined rapidly over recent decades. Here the authors quantify changes in body size distributions for Pacific salmon in Alaska and examine the causes and consequences of size declines for ecosystems, food security, and commercial fisheries.
Nature Communications, Published online: 19 August 2020; doi:10.1038/s41467-020-17814-0 The feasibility of molecular assemblers as a device to control chemical reactions by positioning molecules with atomic precision is a matter of debate in the literature. Here the authors describe of a rudimentary synthetic molecular assembler, supramolecular aggregate of bifunctional surfactants produced by th
Nature Communications, Published online: 19 August 2020; doi:10.1038/s41467-020-17835-9 To optimize operating conditions of large scale semiconductor quantum devices, a large parameter space has to be explored. Here, the authors report a machine learning algorithm to navigate the entire parameter space of gate-defined quantum dot devices, showing about 180 times faster than a pure random search.
Nature Communications, Published online: 19 August 2020; doi:10.1038/s41467-020-17709-0 Swarming bacterial populations can exhibit antibiotic resistance, despite sustaining considerable cell death. Here, Bhattacharyya et al. show that killed cells release periplasmic protein AcrA, which activates efflux pumps on the surface of live cells, thus enhancing antibiotic resistance in the surviving cell
Nature Communications, Published online: 19 August 2020; doi:10.1038/s41467-020-18013-7 Histone methyltransferase, DOTL1 is implicated in the pathogenesis of MLL-rearranged leukemia, however, not much is known of its role in prostate cancer (PCa). Here, the authors report that DOTL1 inhibition suppresses both androgen receptor and MYC pathways in a negative feed forward manner to reduce growth of
Nature Communications, Published online: 19 August 2020; doi:10.1038/s41467-020-17961-4 The relationship between DNA damage response (DDR) and regulation of the tolerance to glucose restriction is currently unclear. Here the authors reveal that maintaining a physiological level of histones by Rad53-Spt21 is necessary for glucose tolerance via multiple parallel pathways, including derepression of
Nature Communications, Published online: 19 August 2020; doi:10.1038/s41467-020-17938-3 Directing the position, orientation, and long-range lateral order of block copolymer domains to produce technologically-useful, sublithographic patterns is a challenge. Here, the authors present a promising approach to overcome the challenge by directing assembly using spatial boundaries between planar, low-re
Nature Communications, Published online: 19 August 2020; doi:10.1038/s41467-020-18023-5 Author Correction: The solute carrier SLC9C1 is a Na + /H + -exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding
Lukningen af lægevagtkonsultationer i Skagen, Brovst og Farsø har fået hård kritik. Region Nordjylland overvejer at lade andre faggrupper træde i stedet for de praktiserende læger.
We are closer than ever to actually putting human beings on Mars, but exactly how close is very much still up for debate. Getting there is one thing, and we eventually may not have a choice, but there are a number of problems that need to be solved before our species can call the Red Planet home. In this video, former NASA astronaut Leland Melvin, educator Bill Nye, science journalist Stephen Pet
Fem frågor till Amy Loutfi, vicerektor för AI och professor i datavetenskap vid Örebro universitet. Amy Loutfi är en av deltagarna i Omstartskommissionen där experter inom olika områden tar fram en handfast plan för hur Sverige kan starta om efter coronakrisen.
The good news is that our natural defences can eliminate the virus and scientists are making progress with antiviral therapies Zania Stamataki is a senior lecturer in viral immunology Coronavirus – latest updates About nine months ago – as we now all know – a new coronavirus jumped to humans, causing a complex respiratory disease called Covid-19. The virus breezed through the planet with ease , h
Hur ser malmkroppen i Kirunaområdet ut? En kartläggning av Kiruna under jord ska ge svar. – Vi sammanställer alla tillgängliga data i en enda modell för att få reda på hur berggrunden ser ut på djupet, säger Tobias Bauer, biträdande professor i malmgeologi vid Luleå tekniska universitet. I januari 2018 kom nyheten att malmkroppen i Kiruna inte fortsätter med samma volym som förväntat. Mineraliser
Health experts say prime minister discussing coercive measures early risked driving hesitant Australians away The health minister Greg Hunt says the federal government will not "force vaccinations on any Australian" and Scott Morrison has clarified they would not be compulsory after experts expressed concern that earlier talk of "mandatory" vaccination might drive hesitant Australians away. The p
California staved off another round of rolling blackouts but faced a renewed threat Wednesday from a searing heat wave, raging wildfires and even a chance of thunderstorms and flooding in some southern areas.
Praktiserende læger bør kunne stille krav til patienter om at bære mundbind, mener praktiserende læge Lise Høyer, der har givet syv positive covid-19 svar på 14 dage.
Researchers have developed a new instrument that has, for the first time, measured tiny light-evoked deformations in individual rods and cones in a living human eye. The new approach could one day improve detection of retinal diseases such as age-related macular degeneration, a leading cause of blindness in people over 55 worldwide.
A year ago this month, the forest around the town of Novo Progresso erupted into flames—the first major blazes in the Brazilian Amazon's dry season that ultimately saw more than 100,000 fires and spurred global outrage against the government's inability or unwillingness to protect the rainforest.
The thylacine, that famous extinct Australian icon colloquially known as the Tasmanian Tiger, is revealed to have been only about half as big as once thought—not a "big" bad wolf after all.
The thylacine, that famous extinct Australian icon colloquially known as the Tasmanian Tiger, is revealed to have been only about half as big as once thought—not a "big" bad wolf after all.
Despite decades of study, exactly how herpesviruses invade our cells remains something of a mystery. Now researchers studying one herpesvirus, the varicella zoster virus (VZV) that causes chicken pox, may have found an important clue: A key protein the virus uses to initiate infection does not operate as previously thought, researchers at Stanford University and the Department of Energy's SLAC Nat
Despite decades of study, exactly how herpesviruses invade our cells remains something of a mystery. Now researchers studying one herpesvirus, the varicella zoster virus (VZV) that causes chicken pox, may have found an important clue: A key protein the virus uses to initiate infection does not operate as previously thought, researchers at Stanford University and the Department of Energy's SLAC Nat
Sorghum, a common food item in regions of Africa and Asia, has one missing puzzle piece. The missing piece? Protein digestibility, which researchers in the Department of Agronomy at Kansas State University are trying to find.
If you've ever been woken up before sunrise by the trilling and chirping of birds outside your window, you may have wondered: why do birds sing so loud, so early in the morning?
Penn State researchers, in a recent study, were surprised to learn that they could take the exact same number of seeds from the same plants, put them in agricultural fields across the Mid-Atlantic region and get profoundly different stands of cover crops a few months later.
Plastic waste in the ocean is an increasing problem for wildlife, including seabirds who frequently mistake it for food. However, ingested plastic does not just pose physical risks for such birds. A new study in open-access journal Frontiers in Environmental Science is the first to show that plastic waste can release chemicals into the stomach oil of seabirds over time, potentially posing a threat
W hat does it mean to call a woman a "Karen"? The origins of any meme are hard to pin down, and this one has spread with the same intensity as the coronavirus, and often in parallel with it. Karens are " the policewomen of all human behavior ." Karens don't believe in vaccines. Karens have short hair. Karens are selfish. Confusingly, Karens are both the kind of petty enforcers who patrol other pe
Shipwrecks act as artificial reefs and provide a substrate and nutrients for a great diversity of microorganisms, which can contribute to either the deterioration or preservation of the ship. Precisely how diverse such communities are, and how they are organized, is still unknown. Here, researchers from East Carolina University in Greenville, North Carolina, identify the bacteria associated with a
Bees and flowers seem inseparable harbingers of spring, but what happens when pollinators emerge later than their sources of nectar and pollen? Reporting on the first community-wide assessment of 67 bee species of the Colorado Rockies, ecologists Michael Stemkovski of Utah State University and Rebecca Irwin of North Carolina State University say "phenological mismatch," changing timing of life cyc
More than 170 teams of researchers are racing to develop a safe and effective vaccine. Here is their progress Researchers around the world are racing to develop a vaccine against Covid-19, with more than 170 candidate vaccines now tracked by the World Health Organization (WHO). Continue reading…
Sorghum, a common food item in regions of Africa and Asia, has one missing puzzle piece. The missing piece? Protein digestibility, which researchers in the Department of Agronomy at Kansas State University are trying to find.
If you've ever been woken up before sunrise by the trilling and chirping of birds outside your window, you may have wondered: why do birds sing so loud, so early in the morning?
Plastic waste in the ocean is an increasing problem for wildlife, including seabirds who frequently mistake it for food. However, ingested plastic does not just pose physical risks for such birds. A new study in open-access journal Frontiers in Environmental Science is the first to show that plastic waste can release chemicals into the stomach oil of seabirds over time, potentially posing a threat
Bees and flowers seem inseparable harbingers of spring, but what happens when pollinators emerge later than their sources of nectar and pollen? Reporting on the first community-wide assessment of 67 bee species of the Colorado Rockies, ecologists Michael Stemkovski of Utah State University and Rebecca Irwin of North Carolina State University say "phenological mismatch," changing timing of life cyc
It's not a surprise to anyone that numerous vertebrate species are being sold at different wildlife markets, but at the moment there is still no comprehensive understanding of how much people are involved in those actions in Laos (Lao PDR), nor what the impact on local wildlife populations really is.
It's not a surprise to anyone that numerous vertebrate species are being sold at different wildlife markets, but at the moment there is still no comprehensive understanding of how much people are involved in those actions in Laos (Lao PDR), nor what the impact on local wildlife populations really is.
Reporting on the first community-wide assessment of 67 bee species of the Colorado Rockies, ecologists Michael Stemkovski of Utah State University and Rebecca Irwin of North Carolina State University say "phenological mismatch," changing timing of life cycles between bees and flowers, caused by climate change, has the potential to disrupt a mutually beneficial relationship.
PLUS. ANALYSE: Mens dansk klimapolitik nærmer sig efterårets sværdslag om CO2-afgift, nordsøolie og madvaner, truer såkaldt CO2-lækage med at punktere indsatsen.
Researchers have designed a new X-ray classification system for adult idiopathic scoliosis that can more precisely define which parts of the spine need correction
Scientists provide the first interdisciplinary assessment of human involvement into the terrestrial vertebrate trade in Laos and its impact on the survival of the local fauna populations. Sixty-six traded species found on wildlife trade markets were documented in the paper, published in the open-access journal Nature Conservation, and more than half of them were found to be the species protected e
A study of 181 patients at 16 sites across the country who test negative for two antibodies long known to cause muscle-weakening myasthenia gravis, found that about 15% test positive for one of two newly discovered antibodies that also attack the point of communication between nerves and muscle.
The Korea Institute of Science and Technology (KIST) has made an announcement about the technology to extract high-purity hydrogen from ammonia and generate electric power in conjunction with a fuel cell developed by a team led by Young Suk Jo and Chang Won Yoon from the Center for Hydrogen and Fuel Cell Research. This confirms the possibility of using ammonia as a hydrogen carrier to transport la
Women with high blood pressure during pregnancy are at an increased risk for chronic hypertension, diabetes, coronary artery disease, stroke, and early cardiovascular death. A new study suggests that they may also be at risk for more bothersome menopause symptoms, including hot flashes. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS
Women with a history of high blood pressure disorders during pregnancy are more likely to experience bothersome menopausal symptoms such as hot flashes and night sweats, according to a study published Wednesday, Aug. 19, in Menopause: The Journal of the North American Menopause Society.
Migration and dispersal are vastly different activities with very different benefits and risks. NCBS Grad student Vaishali Bhaumik and her advisor Dr Krushnamegh Kunte decided to investigate the effects of such activities on the morphology (form and structure) and reproduction of butterflies.
Researchers find distinct differences in the composition of microbial communities on and around the 1960s Pappy Lane shipwreck in Pamlico Sound, North Carolina, suggesting niche partitioning based on biotic and abiotic conditions. The study also identified a new strain of iron-oxidizing bacteria that may contribute to biocorrosion. These results will be useful for the conservation of coastal shall
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