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Scientists 'strongly condemn' rumors and conspiracy theories about origin of coronavirus outbreak
A statement in The Lancet assails misinformation about the possibility that COVID-19 came from a lab in Wuhan, China
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Controlling CAR T cells with light selectively destroys skin tumors in mice
UC San Diego bioengineers have developed a control system that could make CAR T-cell therapy safer and more powerful when treating cancer. By programming CAR T cells to switch on when exposed to blue light, the researchers controlled the cells to destroy skin tumors in mice without harming healthy tissue.
1h
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CRISPR Can Create Unwanted Duplications During Knock-ins
A new study in mice documents frequent undesirable repeats of DNA insertions that are not detected using standard PCR analysis.
14 min
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Danskledet forskningsgruppe kommer lidt tættere på sandheden om antihydrogen
PLUS. På Cern er fysikerne kommet tættere på at besvare spørgsmålet, om der er en forskel på hydrogen og antihydrogen – og dermed en forklaring på, hvorfor Universet består af stof frem for antistof.
3h
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Fungal pathogens tap human iron stores to survive immunity
Candida species, the most prevalent opportunistic human fungal pathogens, affect severely immunocompromized individuals, and can cause severe invasive infections. The steep increase in infections by multidrug-resistant Candida glabrata pathogens has been posing serious therapeutic challenges. The prime risk factor for Candida infections is a severe immunosuppression, as often seen in the aging pop
6h
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Minister og DTU skyder gratis offentlig transport ned: Voldsomt dyrt og frister få bilister
PLUS. DF-forslaget om gratis offentlig transport skydes nu ned af transportministeren, efter at beregninger viser, at det risikerer at lamme den kollektive transport og kun medfører få procents fald i bilkørsel og CO2-udledning.
6h
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Prenatal phthalate exposure associated with autistic traits in young boys
Exposure in the womb to phthalates, a group of endocrine-disrupting chemicals present in cosmetics and other common household products, was associated with autistic traits in boys, ages 3 and 4, but not in girls, according to a new study led by a University of Massachusetts Amherst environmental epidemiologist.
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Altered potassium levels in neurons may cause mood swings in bipolar disorder
A sweeping new set of findings by Salk researchers reveals previously unknown details explaining why some neurons in bipolar patients swing between being overly or under excited. The researchers used experimental and computational techniques to describe how variations in potassium and sodium currents in the brain cells of people with bipolar disorder may help to further explain why some patients r
3h
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Första svenska transplantationen av livmoder från avliden donator
Det svenska teamet bakom forskningen kring livmodertransplantationer har för första gången genomfört en transplantation med livmoder från avliden donator. Ingreppet skedde utan komplikationer och mottagaren mår bra. Transplantationen gjordes i december 2019, under ledning av Mats Brännström, överläkare och professor i obstetrik och gynekologi på Sahlgrenska akademin vid Göteborgs universitet. Ytt
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Fynske robotter skal bekæmpe coronavirus i Kina
En selvkørende dansk robot fra UVD Robots, er klar til at blive sendt til Kina for at bekæmpe coronavirus på kinesiske hospitaler. Ordren er kommet i hus på kort tid og beløber sig til et tocifret millionbeløb.
5h
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'We must cultivate the natural curiosity and capabilities of children': Alan Finkel's 2020s vision
As Australia's chief science nerd, I found lessons for today in this obscure piece of science history. It can help us map our nation's future About this series Let me share a story with you. It is a story of discovery and exploration. We begin in 1751, in a small village in the north-east of France, when Joseph Lepaute Dagelet was born. Growing up, Dagelet looked up to his brother, Dominique, who
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When parents should worry about teen girls' selfies
Adolescent girls who invest a lot of time in editing and selecting the perfect selfie may feel more body shame and appearance anxiety, researchers found.
3h
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CEA declares Anne Peyroche's data fakery scientifically correct
Former CNRS president Anne Peyroche has been symbolically sanctioned for research misconduct. Despite previous fraud findings, conclusions are not affected, and so is her employment by the Atomic Energy Commission. I present two more falsified figures.
9h
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In YouTube 'Edutainment,' Minimal Control for Scientific Accuracy
While Youtuber Siraj Raval's videos have been praised for their high production quality and accessibility, the self-described technology activist's work has recently been criticized, raising questions about qualifications, substance, and accuracy on a platform that provides science education for millions.
11h
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Public Attitude Toward Science
New Pew research findings show confidence in science remains high, but there are some important caveats.
8h
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The psychology of infidelity: Why do we cheat?
Results of a 2005 study show that there is a significant difference between cheaters and non-cheaters when it comes to the Big Five model of personality traits. Poor self control, selfishness, anger, boredom, and attention-seeking are the most common reasons a person is unfaithful in their relationship. However, a 2018 study suggests that even infidelity, which is inherently a selfish behavior, i
2h
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You can't fight feelings with facts: start with a chat
Nature, Published online: 19 February 2020; doi:10.1038/d41586-020-00452-3 I donned a sandwich board inviting questions on evolution and learnt three crucial lessons about public engagement on divisive issues, writes Maggie Ryan Sandford.
8h
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YouTube Gaming's Most-Watched Videos Are Dominated by Scams and Cheats
YouTube is littered with bot-driven videos promising big in-game riches—that also try to steal your personal information.
20h
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Forskere lokaliserer nye koordinater i hjernen på ansigts-blinde
Danske og norske forskere er kommet et skridt nærmere på at forstå, hvor i hjernen problemet…
10h
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A new world record for the conversion of solar energy to electricity using quantum dots
submitted by /u/cake_donut [link] [comments]
10h
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Climate and plant community diversity in space and time [Ecology]
Climate strongly shapes plant diversity over large spatial scales, with relatively warm and wet (benign, productive) regions supporting greater numbers of species. Unresolved aspects of this relationship include what causes it, whether it permeates to community diversity at smaller spatial scales, whether it is accompanied by patterns in functional and…
20h
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Climate change: Fertiliser could be used to power ocean-going ships
Ammonia, the key ingredient of fertiliser, can be burned in ships' engines in place of polluting diesel.
13h
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Could Earth's Heat Solve Our Energy Problems?
submitted by /u/mytwm [link] [comments]
16h
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Could water solve the renewable energy storage challenge?
Seasonally pumped hydropower storage could provide an affordable way to store renewable energy over the long-term, filling a much needed gap to support the transition to renewable energy, according to a new study from IIASA scientists.
5h
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Extremväder slår värst på förnybara energikällor
Klimatförändringar med tilltagande stormar och värmeböljor, får också följder för vår energiförsörjning. Ett internationellt forskarlag har nu tagit fram en ny metod för att beräkna hur extremväder inverkar på energisystemen. Ofta beskrivs klimatförändringar i termer av genomsnittliga temperaturförändringar. Men det är i första hand extrema väderhändelser, som köldknäppar, höststormar och sommarh
6h
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Focus on food would help solve climate change, says study
A paper released today by the journal Nature Food presents a new global food system approach to climate-change research that brings together agricultural production, supply chains and consumption. When these activities are considered together, they represent 21 to 37 percent of total human-caused greenhouse gas emissions, the paper notes. It says that the new approach would enable a fuller assessm
6h
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Fossil Fuels Are to Blame for Soaring Methane Levels, Study Shows
The findings add urgency of efforts to cut emissions of methane, a powerful greenhouse gas routinely leaked or intentionally released into the atmosphere.
4h
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Fossil Fuels Contributes More Methane Than Previously Estimated
Knowing how much methane comes from where has been challenging, but new ice cores have revealed new info.
35 min
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Geus: Vi ser klimaændringer, som vi først havde forventet om 20-30 år
De vandmængder, der har oversvømmet flere veje og byområder, er af en størrelse, som vi først havde forventet at se om 20-30 år, siger seniorrådgiver Hans Jørgen Henriksen fra Geus.
9h
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Global airborne sampling reveals a previously unobserved dimethyl sulfide oxidation mechanism in the marine atmosphere [Earth, Atmospheric, and Planetary Sciences]
Dimethyl sulfide (DMS), emitted from the oceans, is the most abundant biological source of sulfur to the marine atmosphere. Atmospheric DMS is oxidized to condensable products that form secondary aerosols that affect Earth's radiative balance by scattering solar radiation and serving as cloud condensation nuclei. We report the atmospheric discovery…
20h
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Global relationships that determine bird diversity on islands uncovered
It is known that biodiversity is unevenly distributed across the planet. But why do some islands such as the Galápagos and Hawaii harbour so many unique species of birds? In the 1960's, Robert MacArthur & Edward Wilson proposed what was to become a highly influential theory in biology: the Theory of Island Biogeography. This theory predicts the number of species expected on any given island as a f
5h
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Global resource potential of seasonal pumped hydropower storage for energy and water storage
Nature Communications, Published online: 19 February 2020; doi:10.1038/s41467-020-14555-y The potential of seasonal pumped hydropower storage (SPHS) plant to fulfil future energy storage requirements is vast in mountainous regions. Here the authors show that SPHS costs vary from 0.007 to 0.2 US$ m−3 of water stored, 1.8 to 50 US$ MWh−1 of energy stored and 0.37 to 0.6 US$ GW−1 of installed power
10h
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Global warming causing 'irreversible' mass melting in Antarctica. The hottest temperature ever recorded in Antarctica of 18.3 deg C ( 64. 94 F) was taken at a research base there on Feb 6. If hotter temperatures were to sustain, they could cause an extreme global sea level rise.
submitted by /u/Wagamaga [link] [comments]
12h
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Here are 5 practical ways trees can help us survive climate change
As the brutal reality of climate change dawned this summer, you may have asked yourself a hard question: am I well-prepared to live in a warmer world?
6h
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How to heal our planet
Four new books on climate change offer answers to one of the 21st century's most pressing dilemmas
15h
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Humanity's methane problem could be way bigger than scientists thought. According to a new study, far less of the powerful greenhouse gas comes from natural sources than previously understood.
submitted by /u/ngt_ [link] [comments]
2h
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India's annual coal power output falls for first time in a decade
submitted by /u/nirjhari [link] [comments]
2h
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Jeff Bezos spytter 70 milliarder i klimakampen: Hvad bør han bruge pengene på?
Vi har spurgt klimaforskere, hvad den bedste investering ville være for klimaet.
2h
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Klimatavtrycket från norsk lax kan minskas
Klimatavtrycket av odlad lax har ökat, medan det för vildfångad fisk har minskat. Det visar en livscykelanalys av norsk vildfångad och odlad fisk samt skaldjur. Det finns stora möjligheter att minska klimatavtrycket inom fiskenäringen, särskilt för laxodling. Norsk sjömat utgör en stor del av sjömaten vi äter i Sverige. Sedan 2009 har norsk laxodling vuxit kraftigt och anläggningarna har blivit s
5h
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NRL researchers monitor changing Arctic using sound
U.S. Naval Research Laboratory scientists developed Ice-tethered Acoustic Buoys to monitor the acoustic and oceanographic environment in the changing Arctic. The buoys provide critical oceanographic data to improve prediction capabilities of ocean and climate models.
1h
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Preindustrial 14CH4 indicates greater anthropogenic fossil CH4 emissions
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-1991-8 Isotopic evidence from ice cores indicates that preindustrial-era geological methane emissions were lower than previously thought, suggesting that present-day emissions of methane from fossil fuels are underestimated.
5h
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Researchers uncover the genetics of how corn can adapt faster to new climates
Maize is a staple food all over the world. In the United States, where it's better known as corn, nearly 90 million acres were planted in 2018, earning $47.2 billion in crop cash receipts.
5h
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Supercool materials that send heat to space: Every object on Earth radiates heat, but the planet's blanket-like atmosphere absorbs most of it and radiates it back. Infrared rays between 8 and 13 micrometres in wavelength, however, are not captured by the atmosphere and escape into cold outer space.
submitted by /u/ngt_ [link] [comments]
4h
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Time-evolving sea-surface warming patterns modulate the climate change response of subtropical precipitation over land [Environmental Sciences]
Greenhouse gas (GHG) emissions affect precipitation worldwide. The response is commonly described by two timescales linked to different processes: a rapid adjustment to radiative forcing, followed by a slower response to surface warming. However, additional timescales exist in the surface-warming response, tied to the time evolution of the sea-surface-temperature (SST)…
20h
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Timing and magnitude of Southern Ocean sea ice/carbon cycle feedbacks [Earth, Atmospheric, and Planetary Sciences]
The Southern Ocean (SO) played a prominent role in the exchange of carbon between ocean and atmosphere on glacial timescales through its regulation of deep ocean ventilation. Previous studies indicated that SO sea ice could dynamically link several processes of carbon sequestration, but these studies relied on models with simplified…
20h
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Vejdirektoratet: Lavere hastighed på motorvejen vil kun give lille klimaeffekt
En hastighedsnedsættelse fra 130 km/t til 110 km/t vil kun reducere CO₂-udledningen fra trafikken med 0,7 procent.
10h
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Virtually all the world's demand for electricity to run transport and to heat and cool homes and offices, as well as to provide the power demanded by industry, could be met by renewable energy by mid-century. This is the consensus of 47 peer-reviewed research papers from 13 independent groups
submitted by /u/Wagamaga [link] [comments]
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We've Vastly Underestimated How Much Methane Humans Are Spewing Into The Atmosphere
But there's a silver lining, too.
2h
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What to do when cutting emissions alone is no longer enough
Global emissions reach about 40 billion tons each year. Such a massive number can be hard to conceptualize, but chemical engineer Jennifer Wilcox offers some context: Approximately 10 billion of these come from the transportation sector alone.
5h
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Adidas and Puma warn of coronavirus sales drag
German sportswear makers generate about a third of revenues in Asia
8h
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Breakthrough in coronavirus research results in new map to support vaccine design
Researchers have made a critical breakthrough toward developing a vaccine for the 2019 novel coronavirus by creating the first 3D atomic scale map of the part of the virus that attaches to and infects human cells. Mapping this part, called the spike protein, is an essential step so researchers around the world can develop vaccines and antiviral drugs to combat the virus. The paper is publishing We
5h
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China is using mass surveillance tech to fight new coronavirus spread
QR codes, tracking apps and drones at toll booths are just some of the tech tools China is deploying to monitor the spread of the new coronavirus
9h
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China to expel three Wall Street Journal reporters
Decision comes a day after US designates Chinese media outlets as propaganda agents
8h
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Chinese government bond yields hit four-year low
US, European investors bet that Beijing will deploy stimulus to counter virus effects
8h
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Chinese Insurance Firms are using Blockchain for Coronavirus (COVID-19) Claims
The Coronavirus is all anyone has spoken about for weeks now. Mostly, it has been for negative reasons, but there is something positive to come out of the whole ordeal – another use case of Blockchain Technology! Insurance providers in China are using blockchain tech to fast track claims amid the coronavirus (covid-19) outbreak, and here is exactly how they have done that: https://4king.com/chine
34 min
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Coronavirus Epidemic Keeps Growing, but Spread in China Slows
The World Health Organization said China's drastic limits on people's movement had helped, but experts cautioned against predicting that the worst was over.
20h
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Coronavirus Is Devastating Chinese Tourism
YANGON—Last month, on January 19, Myanmar's state-run newspaper left no question as to what was the biggest story of the day. The paper carried page after page of dry reports documenting the movements and meetings of visiting Chinese President Xi Jinping. Inside were photos of Xi and Myanmar's leader, Aung San Suu Kyi , sitting in gilded chairs behind a table draped in red, yellow, and green fabr
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Coronavirus Live Updates: Cambodia Says Cruise Ship Passengers Are Virus-Free
The authorities said they had tested 740 passengers from the Westerdam, a cruise ship that was permitted to dock in the country last week after being turned away from ports across Asia.
15h
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Coronavirus name, animal-research data and a Solar System snowman
Nature, Published online: 19 February 2020; doi:10.1038/d41586-020-00453-2 The latest science news, in brief.
7h
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Coronavirus outbreak slashes China carbon emissions: study
The coronavirus epidemic that has paralysed the Chinese economy may have a silver lining for the environment.
8h
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Coronavirus/Singapore: hotels half-empty
The swift rebound that followed the Sars epidemic cannot be expected this time
8h
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Coronavirus: cruise industry caught in the eye of the storm
Quarantined passengers, cancelled sailings and worries over infection weigh on the $45bn sector
8h
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Coronavirus: Diamond Princess exodus begins amid criticism over quarantine
More than 3,000 people to disembark over three days after ship proved a fertile breeding ground for Covid-19 Deaths rise over 2,000 in China – latest updates Hundreds of passengers have begun leaving the stricken Diamond Princess in Japan after testing negative for the coronavirus Covid-19, ending two weeks of quarantine that experts say failed to prevent the virus spreading onboard. Japanese TV
15h
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Coronaviruset: Genombrott i sökandet efter vaccin
Forskare har gjort ett viktigt framsteg i utvecklandet av ett vaccin mot det nya coronaviruset covid-19. De har lyckats skapa en 3D-kopia av den del av viruset som fäster vid och infekterar människans celler.
5h
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Foreign Office tells Britons not to leave cruise ship struck by coronavirus
Passengers who disembark Diamond Princess may not be allowed to board evacuation flight later in week, FCO warns Coronavirus: live updates British passengers stuck on the cruise ship in Japan where more than 600 people have been infected with the coronavirus have have been told to stay onboard by the Foreign Office, while those who are evacuated face a 14-day quarantine in the UK. Japanese author
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Hunt For New Coronavirus Treatments Includes Gene-Silencing And Monoclonal Antibodies
The new coronavirus has spurred biotech labs in universities and companies to try to find new approaches to stopping the virus — from blocking its key enzymes to interfering with its genetics. (Image credit: Rani Levy)
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Is a coronavirus vaccine on the way?
Researchers have created the first 3D atomic scale map of the part of the 2019 coronavirus that attaches to and infects human cells. Mapping this part, called the spike protein, is an essential step so researchers around the world can develop a vaccine and antiviral drugs to combat the coronavirus. The researchers are also working on a related viable vaccine candidate stemming from the research.
1h
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Scientist decries 'completely chaotic' conditions on cruise ship Japan quarantined after viral outbreak
Japanese government also slow to release epidemiological data about the Diamond Princess , critics say
1h
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The Lancet: Egypt, Algeria and South Africa estimated to be at highest risk of new coronavirus cases in Africa
Increased resources, surveillance, and capacity building should be urgently prioritised in African countries with moderate risk of importing cases of novel coronavirus disease 2019 (COVID-19), as these countries are estimated to be ill-prepared to detect cases and limit transmission.
4h
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To Prevent Next Coronavirus, Stop the Wildlife Trade, Conservationists Say
China Wall Street Journal
Conservationists see a persistent threat of epidemics so long as tens of millions of animals are traded in Southeast Asia.
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US warns against releasing cruise ship passengers in Japan
Centers for Disease Control says those disembarking vessel pose 'ongoing risk'
17h
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Vast Majority of Coronavirus Infections Are Mild, Huge Study Has Revealed
Only some people are more at risk.
19h
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New test identifies poisonous mushrooms
A simple, portable test that can detect the deadliest of the mushroom poisons in minutes has been developed by Agricultural Research Service (ARS) scientists and their colleagues.
3h
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A new way to assess male fertility
Current tests for male fertility include measuring the concentration and motility of spermatozoa. However, other characteristics of sperm, such as their ability to follow a chemical trail to the egg, can influence the likelihood of fertilization. Now, researchers have devised a quick and convenient microfluidic chip to assess this chemotactic response of spermatozoa, which could help provide a mor
4h
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First baby born to cancer patient from eggs matured in the lab and frozen
Fertility doctors in France have announced the birth of the first baby to be born to a cancer patient from an immature egg that was matured in the laboratory, frozen, then thawed and fertilized five years later. The report is published in Annals of Oncology.
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Watch 2 robots work together to make a hot dog
An advance in machine learning allows two robots, named Jaco and Baxter, to make a hot dog. Teaching robots to perform complex tasks involves a framework that could apply to a host of tasks, like identifying cancerous spots on mammograms or better understanding spoken commands to play music. But first, as a proof of concept, they're making franks. Researchers still don't fully understand exactly
6h
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What birdsong tells us about brain cells and learning
New research by neuroscientists at the University of Chicago uses a unique model — the intricate mating songs of birds — to show how the intrinsic properties of neurons are closely tied to the complex processes of learning.
10h
#77 Musik på recept
Mød to personer, der drømmer om at se mange flere instumenter og musikere på Danmarks hospitaler. Bl.a. Anna Lidell, formand i dansk kompinistforening, der vil musikken ud på hospitalsgangen.
4h
{beta}-Arrestin2 oligomers impair the clearance of pathological tau and increase tau aggregates [Neuroscience]
Multiple G protein-coupled receptors (GPCRs) are targets in the treatment of dementia, and the arrestins are common to their signaling. β-Arrestin2 was significantly increased in brains of patients with frontotemporal lobar degeneration (FTLD-tau), a disease second to Alzheimer's as a cause of dementia. Genetic loss and overexpression experiments using genetically…
20h
'Electronic nose' sniffs out bad flavors in beer
A low-cost "electronic-nose," or "e-nose," uses machine learning to quickly assess beer quality based on its aroma, researchers report. The device is portable, allowing brewers to use it for rapid and reliable quality assessment on the production line. It also has the potential to be used to assess other food and beverages at all stages of production and has already been tested to detect smoke ta
5h
2 km high backpack jet flight over Dubai
submitted by /u/SFinTX [link] [comments]
4h
3-D imaging the flavor content of the nucleon
The Jefferson Lab Hall A Collaboration, in an experiment led by researchers at Faculté des Sciences de Monastir in Tunisia, Institut de Physique Nucléaire d'Orsay in France and Old Dominion University in the United States, has recently gathered the first experimental observations of deeply virtual Compton scattering (DVCS) in neutrons. Their experiment, whose results were published in Nature Physi
5h
8 tips to make your gadget's battery last longer
These best practices can make the lithium-ion batteries in your devices last longer, researchers say. Researchers plowed through scores of academic papers and manufacturers' user manuals, as well as information on customer-support websites, to develop the list. "By minimizing exposure to the conditions that accelerate degradation, batteries can last longer. And this has a positive environmental i
5h
A Coding School Tuition Model Spreads to 4-Year Colleges
Income share agreements first gained popularity with tech bootcamps. Now some traditional universities are offering the tools as substitutes for student loans.
10h
A Far-Right Warning From Germany
The far right in Germany may be confined to the opposition benches, but they are proving just how disruptive they can be. Earlier this month, in the country's eastern state of Thuringia, the Alternative for Germany (AfD) joined Chancellor Angela Merkel's ruling center-right Christian Democrats and the pro-business Free Democrats to elect the latter party's candidate for state governor. That a reg
14h
A High Throughput Approach to Reconstruct Partial-Body and Neutron Radiation Exposures on an Individual Basis
Scientific Reports, Published online: 19 February 2020; doi:10.1038/s41598-020-59695-9
11h
A molecular gradient along the longitudinal axis of the human hippocampus informs large-scale behavioral systems
Nature Communications, Published online: 19 February 2020; doi:10.1038/s41467-020-14518-3 The human hippocampus plays a role in many different cognitive systems. Here the authors find that a single pattern of brain gene expression can predict how different parts of the hippocampus interact with the rest of the brain.
10h
A molecular switch regulating transcriptional repression and activation of PPARγ
Nature Communications, Published online: 19 February 2020; doi:10.1038/s41467-020-14750-x Structural studies of nuclear receptor transcription factors revealed that nearly all nuclear receptors share a conserved helix 12 dependent transcriptional activation mechanism. Here the authors present two crystal structures of peroxisome proliferator-activated receptor gamma (PPARγ) in an inverse agonist/
11h
A new model of the worm C. elegans to progress in the study of a rare disease
he IDIBELL Neurometabolic Diseases group, with international collaboration, has identified a model of chromosome X-linked adrenoleukodystrophy (x-ALD) in the earthworm C. elegans, this is a rare disorder of the nervous system with no treatment available.
5h
A novel anti-HER2 antibody GB235 reverses Trastuzumab resistance in HER2-expressing tumor cells in vitro and in vivo
Scientific Reports, Published online: 19 February 2020; doi:10.1038/s41598-020-59818-2
11h
A randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared…
The objective of this study was to compare the safety and antitumor activity of F14512 and etoposide phosphate in dogs with spontaneous non-Hodgkin lymphoma and to investigate the potential benefit of F14512 in P-glycoprotein overexpressing lymphomas.
50 min
A salamander named Egoria: Palaeontologists identify new Jurassic amphibian
A group of Russian and German palaeontologists have described a previously unknown genus and species of prehistoric salamanders. The new amphibian is named Egoria malashichevi — in honor of Yegor Malashichev a talented scientist and associate professor of the Department of Vertebrate Zoology at St Petersburg University, who passed away at the end of 2018.
1h
A salary in exchange for our data, new economic system proposed by a researcher from IMDEA Networks
Data and the economy stemming from them are the engine for the fourth industrial revolution. However, and according to Nikolaos Laoutaris, there is a very important leading player who currently receives absolutely nothing of the huge profits generated by the activity: the people who provide these data. Only in a very few cases do the humans producing data receive a measly compensation in kind for
6h
A self-activating orphan receptor
Nature, Published online: 19 February 2020; doi:10.1038/d41586-020-00411-y The first 3D structure of a full-length G-protein-coupled receptor whose natural activator is unknown has been determined, providing insights into an unusual mode of activation and a basis for discovering therapeutics.
5h
A simple dynamic model explains the diversity of island birds worldwide
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2022-5 Using a global molecular phylogenetic dataset of birds on islands, the sensitivity of island-specific rates of colonization, speciation and extinction to island features (area and isolation) is estimated.
5h
A spin wave detective story: Researchers verify surprising behavior in a 2-D magnet
Researchers at the National Institute of Standards and Technology (NIST) have discovered a surprising feature in two-dimensional (2-D) magnets, a new class of materials receiving a great deal of attention. Their finding is the first verification that a signal long thought to be due to vibrations in the lattice—the structure of the material itself—is actually due to a wave of electron spins.
6h
A spookily good sensor
Researchers at The University of Tokyo show how quantum entanglement can be used to produce single-shot detectors with the ability to measure an individual magnon in a magnetic sphere. This work may assist in the study of the foundations of magnetism, as well as the development of sensors that reach the fundamental limit of detection.
6h
AB569, a nontoxic chemical tandem that kills major human pathogenic bacteria [Microbiology]
Antibiotic-resistant superbug bacteria represent a global health problem with no imminent solutions. Here we demonstrate that the combination (termed AB569) of acidified nitrite (A-NO2−) and Na2-EDTA (disodium ethylenediaminetetraacetic acid) inhibited all Gram-negative and Gram-positive bacteria tested. AB569 was also efficacious at killing the model organism Pseudomonas aeruginosa in biofilms an
20h
African Americans forged free lives in Civil War refugee camps
Civil War refugee camps show how African Americans built a future from the ashes of slavery, a historian explains. More than 300 refugee camps sprang up during the war with more than 800,000 African Americans passing through them at some point. Most residents were slaves or ex-slaves fleeing the clutches of their enslavers and the Confederate army , estimates Abigail Cooper, an assistant professo
7h
AI could help make fast-charging, long-lasting electric car batteries
Artificial intelligence is helping optimise the recharging batteries in electric vehicles, balancing speed while maximising lifespan
4h
Air pollution control strategies directly limiting national health damages in the US
Nature Communications, Published online: 19 February 2020; doi:10.1038/s41467-020-14783-2 Decoupling emission reduction target determination, air pollution modelling, and health benefit estimation complicates control strategy design. Here an integrated approach identifies strategies to reduce health damages of air pollution, showing that benefits can be achieved cost-effectively by electrifying s
11h
Algorithms Were Supposed to Fix the Bail System. They Haven't
A nonprofit group encouraged states to use mathematical formulas to try to eliminate racial inequities. Now it says the tools have no place in criminal justice.
8h
Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet
Nature Communications, Published online: 19 February 2020; doi:10.1038/s41467-020-14796-x Metabolic adaptation to different diets results in changes to gene expression. Here, the authors characterise the chromatin landscape and transcriptional network in mice on a diet of high saturated fat, compared to a diet high in carbohydrate, finding a dramatic reprogramming of the liver transcriptional net
10h
Amplification of Duffy binding protein-encoding gene allows Plasmodium vivax to evade host anti-DBP humoral immunity
Nature Communications, Published online: 19 February 2020; doi:10.1038/s41467-020-14574-9 Duffy binding protein (DBP) of Plasmodium vivax is important for invasion and is a potential vaccine candidate. Here, the authors show that PvDBP gene amplification protects P vivax in vitro against invasion inhibitory human monoclonal antibodies and is associated to infection of patients with PvDBP binding
10h
An apple a day might help keep bothersome menopause symptoms away
A healthy diet rich in fruits and vegetables is known to benefit the human body in so many ways. Now a new study suggests that it may also play a role in lessening various menopause symptoms. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).
3h
An experimental test of the area-heterogeneity tradeoff [Ecology]
A fundamental property of ecosystems is a tradeoff between the number and size of habitats: as the number of habitats within a fixed area increases, the average area per habitat must decrease. This tradeoff is termed the "area–heterogeneity tradeoff." Theoretical models suggest that the reduction in habitat sizes under high…
20h
An optimized structure of memristive device for neuromorphic computing systems implemented
Lobachevsky University scientists have implemented a new variant of the metal-oxide memristive device, which holds promise for use in RRAM (Resistive Random Access Memory) and novel computing systems, including neuromorphic ones.
5h
An organic/inorganic electrode-based hydronium-ion battery
Nature Communications, Published online: 19 February 2020; doi:10.1038/s41467-020-14748-5 The authors show a hydronium-ion battery with an organic pyrene-4,5,9,10-tetraone anode and a MnO2@graphite cathode and H3O+ as the charge carrier. In addition to exhibiting promising energy density and power density, this battery works well even under low temperatures ranging from −40 °C to −70 °C.
11h
An update on the Jupiter water mystery
Juno provides more information than Galileo could.
2h
Analytical distributions for detailed models of stochastic gene expression in eukaryotic cells [Biophysics and Computational Biology]
The stochasticity of gene expression presents significant challenges to the modeling of genetic networks. A two-state model describing promoter switching, transcription, and messenger RNA (mRNA) decay is the standard model of stochastic mRNA dynamics in eukaryotic cells. Here, we extend this model to include mRNA maturation, cell division, gene replication,…
20h
Ancient fish dinners chart Sahara's shift from savannah to desert
Bones of fish eaten by humans thousands of years ago offer clue to region's ancient climate The Sahara's shift from savannah with abundant lakes to a largely arid expanse has been traced in the remains of fish eaten thousands of years ago. Researchers analysing material found in a rock shelter in the Acacus mountains in south-west Libya say they have found more than 17,500 animal remains dating f
2h
Ancient gut microbiomes shed light on human evolution
The microbiome of our ancestors might have been more important for human evolution than previously thought. By comparing data from prior studies, the authors revealed that an adaptive gut microbiome could have been critical for human dispersal, allowing our ancestors to survive in new geographic areas.
15h
Ancient humans in the Sahara ate fish before the lakes dried up
As a changing climate dried out the Sahara desert, ancient humans transitioned from eating lots of tilapia and catfish to more mammal-heavy meals
1h
Antidote to pain and negativity? Let it be
Merely a brief introduction to mindfulness helps people deal with physical pain and negative emotions, a new study by researchers at Yale, Columbia, and Dartmouth shows. The effect of mindfulness was so pronounced, they found, that even when participants were subjected to high heat on their forearm, their brain responded as if it was experiencing normal temperature.
1h
Antimatter looks just like matter – which is a big problem for physics
A difference in the properties of matter and antimatter could help explain our universe – but a property called the Lamb shift is similar in particles of both
4h
Assessing aneuploidy with repetitive element sequencing [Genetics]
We report a sensitive PCR-based assay called Repetitive Element AneupLoidy Sequencing System (RealSeqS) that can detect aneuploidy in samples containing as little as 3 pg of DNA. Using a single primer pair, we amplified ∼350,000 amplicons distributed throughout the genome. Aneuploidy was detected in 49% of liquid biopsies from a…
16 min
Author Correction: Near-infrared tunable metalens based on phase change material Ge2Sb2Te5
Scientific Reports, Published online: 19 February 2020; doi:10.1038/s41598-020-60082-7 Author Correction: Near-infrared tunable metalens based on phase change material Ge 2 Sb 2 Te 5
11h
Bacteria on the International Space Station no more dangerous than earthbound strains
Two particularly tenacious species of bacteria have colonized the potable water dispenser aboard the International Space Station (ISS), but a new study suggests that they are no more dangerous than closely related strains on Earth. Aubrie O'Rourke of the J. Craig Venter Institute and colleagues report these findings in a new paper published February 19, 2020 in the open-access journal PLOS ONE.
17 min
Bacterial coexistence driven by motility and spatial competition
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2033-2 In mixed bacterial populations that colonize nutrient patches, a growth–migration trade-off can lead to spatial exclusion that provides an advantage to populations that become rare, thereby stabilizing the community.
5h
'Beat Saber' Is a VR Workout for People Who Don't Like Exercise
The game turns music and sword-fighting into a hardcore fitness activity.
8h
BECEP array installed at South Pole
Professor Clem Pryke and his group are on their way back to Minnesota from the South Pole in Antarctica after completing installation of the new BICEP Array Telescope. Over the next few years this specialized radio telescope will study the Cosmic Microwave Background—an afterglow from the Big Bang—looking for the imprint of gravitational waves from the beginning of time. The project, which has bee
7h
Biodiversity theory backed by island bird data
Nature, Published online: 19 February 2020; doi:10.1038/d41586-020-00426-5 Analysis of a unique global data set reveals how the species diversity of birds is affected by the properties of archipelagos and offers a way to test an influential theory. Has this improved our understanding of island biodiversity patterns.
5h
Biologists develop new defense in fight against crop infections
A team of researchers at the University of Toronto has successfully tested a new strategy for identifying genetic resources critical for the ongoing battle against plant pathogens such as bacteria, fungi, and viruses that infect and destroy food crops worldwide.
12h
Bisphenol A and bisphenol S disruptions of the mouse placenta and potential effects on the placenta-brain axis [Applied Biological Sciences]
Placental trophoblast cells are potentially at risk from circulating endocrine-disrupting chemicals, such as bisphenol A (BPA). To understand how BPA and the reputedly more inert bisphenol S (BPS) affect the placenta, C57BL6J mouse dams were fed 200 μg/kg body weight BPA or BPS daily for 2 wk and then bred….
20h
Boys with inattention-hyperactivity face increased risk for traumatic brain injuries
McGill-led research shows that boys exhibiting inattention-hyperactivity at age 10 have a higher risk for traumatic brain injuries (TBIs) in adolescence and adulthood. Treatments to reduce these behaviours may decrease the risk for TBIs.
5h
BPA-free plastic may still not be safe
Is BPA-free plastic safe? New findings with mice suggest the alternative chemical BPS could be just as harmful. For decades, scientists have studied BPA extensively in animal models with results indicating the chemical plays a role in early pregnancy loss, placental diseases, and various negative health outcomes after birth. As these adverse health effects have become more widely known, companies
1h
Brain and arteries, working together
Researchers shed light on how they communicate to supply blood to areas of heightened neural activity.
2h
Brain measurements can reveal success of alcohol risk messages
By studying how our brains 'synchronise' during shared experiences, social neuroscientists at the University of Konstanz show if alcohol risk messages catch on in an audience and lead to a reduction in drinking.
3h
Breast cancer surgery: Better results with higher case numbers
Increased chances of survival and fewer follow-up operations — positive correlation between volume and quality in the surgical treatment of breast cancer.
4h
Bævere ødelægger buske og træer og skaber kaos: Men det er kaos på den gode måde
Undersøgelse viser, at bævere beriger dyrelivet og mindsker forurening i floder.
10h
Can we quit cobalt batteries fast enough to make electric cars viable?
Electric cars depend on cobalt as a key ingredient in their batteries, but a new analysis reveals we may run out by 2030, while car firm Tesla is moving to other types of battery in China
6h
Cannabis use during pregnancy
The large health care system Kaiser Permanente Northern California provides universal screening for prenatal cannabis use in women during pregnancy by self-report and urine toxicology testing. This observational study used data to examine the association of depression, anxiety, and trauma diagnoses and symptoms with cannabis use by women during pregnancy.
4h
Carrots plus sticks: Study looks at what works to reduce low-value care
The old story of a farmer trying to get a stubborn mule to pull a wagon by dangling a carrot in front of its nose, or hitting its rump with a stick, may not seem to have much to do with the practice of medicine. But a new study suggests that when it comes to making the best use of healthcare dollars, it will take a combination of carrots and sticks to move things forward.
4h
Caveolae in CNS arterioles mediate neurovascular coupling
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2026-1 Caveolae in arteriolar endothelial cells—but not those in neighbouring smooth muscle cells—have a key role in neurovascular coupling, an essential function for meeting acute brain energy demand.
5h
Certain factors linked with discontinuing breast cancer therapy
For women with hormone receptor-positive breast cancer, long-term endocrine therapy can greatly reduce the risk of recurrence. Many women, especially those in underserved populations, do not continue treatment, however. A new Psycho-Oncology study uncovers some of the factors that may be involved.
3h
Changes to Title X mean contraception access for teens could worsen nationwide, study shows
Texas teens lost access to confidential family planning services due to family planning budget cuts and loss of Title X funds, says a new study led by the University of Colorado College of Nursing just published in the Journal of Adolescent Health. This research suggests that contraception access for teens throughout the nation could worsen as new changes to Title X are implemented.
5h
Cheap Nanoparticles Pave the Way for Carbon-Neutral Fuel
A new way to produce nanoparticles—which convert carbon dioxide emissions into fuel—may help a niche green-energy technology go mainstream.
9h
Chlamydia's covert reproduction
UF researchers have resolved a two-decade old mystery centered upon how the bacteria chlamydia divide and reproduce. Newly published results from the lab of Anthony Maurelli, a microbiologist in UF's College of Public Health and Health Professions and the EPI, reveal that how these parasitic pathogens replicate diverges from a nearly universal norm.
7h
Chromatin remodeling factor ARID2 suppresses hepatocellular carcinoma metastasis via DNMT1-Snail axis [Cell Biology]
Recurrence and metastasis remain the major obstacles to successful treatment of hepatocellular carcinoma (HCC). Chromatin remodeling factor ARID2 is commonly mutated in HCC, indicating its important role in cancer development. However, its role in HCC metastasis is largely elusive. In this study, we find that ARID2 expression is significantly decreased…
20h
Closed-loop optimization of fast-charging protocols for batteries with machine learning
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-1994-5 A closed-loop machine learning methodology of optimizing fast-charging protocols for lithium-ion batteries can identify high-lifetime charging protocols accurately and efficiently, considerably reducing the experimental time compared to simpler approaches.
5h
Cobalt supply can meet demand for electric vehicle and electronics batteries
Greater use of electric vehicles might be good for the environment, but further growth hinges on continued availability of critical battery components such as cobalt. Cell phones and other electronics also depend on the element's availability. Supplies of the metal are adequate in the short term, but shortages could develop down the road if refining and recycling aren't ramped up or made more effi
3h
Cognitive experiments give a glimpse into the ancient mind
New study published in PNAS shed light on some of the earliest examples of human symbolic behavior: Ancient engravings were likely produced with aesthetic intent and marked group identity.
6h
Color-Changing Material Unites the Math and Physics of Knots – Facts So Romantic
Reprinted with permission from Quanta Magazine's Abstractions blog . Mathematicians have studied knots for centuries, but a new material is showing why some knots are better than others. Image by karlibri / Shutterstock One sunny day in the summer of 2019, Mathias Kolle, a professor at the Massachusetts Institute of Technology, took a couple of eminent colleagues out sailing. They talked about th
9h
Communicating science can benefit from scientists 'being human'
As social beliefs and values change over time, scientists have struggled with effectively communicating the facts of their research with the public. Now, a team of researchers from the University of Missouri and the University of Colorado believe scientists can gain trust with their audience by showing their human side. The researchers say it can be as simple as using 'I' and first-person narrativ
3h
Comparing outcomes between African-American, white women after mammography-detected triple-negative breast cancer
Researchers compared treatment and survival rates between African American and white women following early detection with mammography of triple-negative breast cancer. African-American women have a higher rate of death from breast cancer compared with white women, a disparity partly explained by a higher rate of this aggressive breast cancer.
4h
Conflicts at Conservation Group IUCN: Investigation
Buzzfeed uncovers trophy hunters among the ranks of the International Union for Conservation of Nature, which, critics say, may be impeding wildlife protection.
55 min
Controversy swirls around adipose-derived cell therapies for reparative medicine
Challenging the US Food and Drug Administration's current approach to evaluating and approving adipose-based cell therapies used in reparative medicine, a group of researchers proposes a new path forward that focuses on patient safety and includes evidence-based medical practice.
3h
Corporate Buzzwords Are How Workers Pretend to Be Adults
If there's anything corporate America has a knack for, it's inventing new, positive words that polish up old, negative ones. Silicon Valley has recast the chaotic-sounding " break things " and " disruption " as good things. An anxious cash grab is now a "monetization strategy," and if you mess up and need to start over, just call it a "pivot" and press on. It's the Uber for BS, you might say. Clo
5h
Count me out of counting seeds
One, two, three, four, five. One, two, three, four, five. Over and over and over. That's the dull routine of any researcher or student tasked with counting weed seeds. But just like technology has made many things in life faster and easier, relief may be coming for seed counters as well.
12h
Cryo-chip overcomes obstacle to large-scale quantum computers
QuTech has resolved a major issue on the road toward a working large-scale quantum computer. QuTech, a collaboration of TU Delft and TNO, and Intel have designed and fabricated an integrated circuit that can controlling qubits at extremely low temperatures. This paves the way for the crucial integration of qubits and their controlling electronics in the same chip. The scientists have presented the
5h
Daily briefing: True random-number generator powered by crystals
Nature, Published online: 19 February 2020; doi:10.1038/d41586-020-00485-8 Really random numbers from crystal growth, caution greets signs that the coronavirus epidemic has peaked and the next chapter for African genomics is being written in Nigeria.
2h
Der er forskel på fejlskøn og fejlbehandling
De fleste læger går på arbejde for at gøre deres bedste. Og når det ikke er nok, er det ikke kun patienten – men også de fleste læger – der lider, skriver speciallæge i almen medicin i kommentar til meningitis-sagen.
9h
Diabetes patients who use online tools manage disease better
In a study published in JAMA Network Open today, Kaiser Permanente scientists report that diabetes patients who used the Kaiser Permanente patient portal and mobile phone app improved their diabetes management outcomes. The large study, involving more than 111,000 patients, was unique in assessing the relationship between the use of online tools and medication adherence and blood glucose levels.
4h
Dietary modification, penetrance, and the origins of congenital malformation [Commentaries]
Molecular genetic diagnostics refers to the branch of clinical medicine dedicated to finding the proximate mutational cause of an abnormality (1). More for practical than theoretical reasons, it generally assumes that a genetic variant is both necessary and sufficient to cause the defect, and hence that there is no need…
20h
Different tick, same repellents: Study shows how to avoid Asian longhorned tick
While the invasive Asian longhorned tick (Haemaphysalis longicornis) has now appeared in 12 states since its first detection in the United States in 2017, new research offers some good news about its potential as a public health threat. The same insect repellents and other personal protective measures recommended to prevent bites from native tick species also appear to be equally effective against
5h
Digital work design will benefit future workforce
New Curtin University-led research has found that the introduction of new technologies such as artificial intelligence, robots and automation into the workforce could potentially benefit employees, rather than replace them, if the right steps are taken.
5h
Direct observation of ligand migration within human hemoglobin at work [Biophysics and Computational Biology]
Hemoglobin is one of the best-characterized proteins with respect to structure and function, but the internal ligand diffusion pathways remain obscure and controversial. Here we captured the CO migration processes in the tense (T), relaxed (R), and second relaxed (R2) quaternary structures of human hemoglobin by crystallography using a high-repetition…
20h
Discovery may illuminate a missing link between atherosclerosis and aging
Using a preclinical model of atherosclerosis, Feinberg and colleagues have uncovered a long, noncoding RNA (lncRNA) that may point the way toward new therapies for atherosclerosis and shed light on why the likelihood of the disease increases with age.
1h
Divergent selection and genetic introgression shape the genome landscape of heterosis in hybrid rice [Agricultural Sciences]
The successful application of heterosis in hybrid rice has dramatically improved rice productivity, but the genetic mechanism for heterosis in the hybrid rice remains unclear. In this study, we generated two populations of rice F1 hybrids with present-day commercial hybrid parents, genotyped the parents with 50k SNP chip and genome…
20h
Divided, we fall: How ant behavior mimics political polarization. "Our findings suggest that division of labor and political polarization—two social phenomena not typically considered together—may actually be driven by the same process."
submitted by /u/ngt_ [link] [comments]
6h
Do Fans of Cartoon Porn Stars Hate (Real) Women?
The fanbase of Projekt Melody—an anime camgirl and the next step in digital sexuality—may overlap with the more misogynistic corners of the internet.
9h
DTU: Sådan kan IC3 genopstå som el- eller hybridtog
PLUS. Ombygning af IC3-tog fra diesel til batteri- eller hybriddrift kan være et kærkommen vej til at få eldrift ind på de ikke-elektricificerede strækninger. Og så kan IC3-e højne serviceniveauet.
7h
Ecuador's "Throat of Fire" Volcano Terrifyingly Near Collapse
Fire. Throat. In Ecuador, one of South America's most active, angry volcanos — given the not-at-all-terrifying name "Throat of Fire" — is on the verge of collapse. While this isn't about to happen tomorrow, it's at serious risk of an event in the near future, one that could no doubt carry potentially devastating ecological and economic consequences. The news comes via ScienceAlert off the publica
3h
EIA Releases 2050 Projections For Energy
submitted by /u/Supersubie [link] [comments]
6h
Electronically driven collapse of the bulk modulus in {delta}-plutonium [Applied Physical Sciences]
Plutonium metal exhibits an anomalously large softening of its bulk modulus at elevated temperatures that is made all the more extraordinary by the finding that it occurs irrespective of whether the thermal expansion coefficient is positive, negative, or zero—representing an extreme departure from conventional Grüneisen scaling. We show here that…
20h
Eliminating viruses in our food with cranberries and citrus fruit
Fresh produce is a major vehicle for noroviruses, a group of viruses that are the most common cause of gastroenteritis in developed countries. However, the viruses are quite resistant to cold pasteurization treatments such as irradiation, which are used to destroy bacteria, moulds, parasites, and insects. The irradiation process uses gamma rays or X-rays to destroy these viruses but at the dose ne
1h
Emergency Recovery Plan could halt catastrophic collapse in world's freshwater biodiversity
With biodiversity vanishing from rivers, lakes and wetlands at alarming speed, a new scientific paper outlines an Emergency Recovery Plan to reverse the rapid decline in the world's freshwater species and habitats—and safeguard our life support systems.
7h
Endothelial-specific YY1 governs sprouting angiogenesis through directly interacting with RBPJ [Developmental Biology]
Angiogenesis, the formation of new blood vessels, is tightly regulated by gene transcriptional programs. Yin Ying 1 (YY1) is a ubiquitously distributed transcription factor with diverse and complex biological functions; however, little is known about the cell-type-specific role of YY1 in vascular development and angiogenesis. Here we report that endothelial…
16 min
Engineering light-controllable CAR T cells for cancer immunotherapy
T cells engineered to express chimeric antigen receptors (CARs) can recognize and engage with target cancer cells with redirected specificity for cancer immunotherapy. However, there is a lack of ideal CARs for solid tumor antigens, which may lead to severe adverse effects. Here, we developed a light-inducible nuclear translocation and dimerization (LINTAD) system for gene regulation to control C
1h
Engineers devise a decision map to identify the best mission type to deflect an incoming asteroid
On April 13, 2029, an icy chunk of space rock, wider than the Eiffel Tower is tall, will streak by Earth at 30 kilometers per second, grazing the planet's sphere of geostationary satellites. It will be the closest approach by one of the largest asteroids crossing Earth's orbit in the next decade.
8h
Enhanced CRISPR-Cas9 correction of Duchenne muscular dystrophy in mice by a self-complementary AAV delivery system
Duchenne muscular dystrophy (DMD) is a lethal neuromuscular disease caused by mutations in the dystrophin gene ( DMD ). Previously, we applied CRISPR-Cas9–mediated "single-cut" genome editing to correct diverse genetic mutations in animal models of DMD. However, high doses of adeno-associated virus (AAV) are required for efficient in vivo genome editing, posing challenges for clinical application
1h
Enriching newborns' environment in the right way helps heal young, injured brains
Preclinical model of oxygen deprivation, a common consequence of prematurity, showed better recovery when exposed to a combination of increased physical activity, socialization and cognitive stimulation.
6h
Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery
Nature Communications, Published online: 19 February 2020; doi:10.1038/s41467-020-14762-7 Hypoxic brain damage associated with premature birth causes lasting neurological impairments. Here, the authors use environmental enrichment to rescue white matter dysmaturation following hypoxia, while identifying a critical window of intervention and oligodendrocyte-specific changes in gene expression.
10h
Episode 3: can we trust science to police itself? – podcast
In our third and final episode, we talk about trust in science. In particular, how historical cases of abuse led many in our groups to question gene editing , science and medicine. If we focus on the past, will we ever move forward? Continue reading…
8h
Essential requirement for nicastrin in marginal zone and B-1 B cell development [Immunology and Inflammation]
γ-secretase is an intramembrane protease complex that catalyzes the proteolytic cleavage of amyloid precursor protein and Notch. Impaired γ-secretase function is associated with the development of Alzheimer's disease and familial acne inversa in humans. In a forward genetic screen of mice with N-ethyl-N-nitrosourea-induced mutations for defects in adaptive immunity, we…
20h
Estimating effects of indoor tanning regulations
This analysis estimated the health and economic consequences of indoor tanning regulations, such as banning indoor tanning devices or prohibiting their use by minors, in North America and Europe compared with current levels of use.
4h
EU proposes rules for artificial intelligence to limit risks
submitted by /u/Captain-Blitzed [link] [comments]
8h
Europe plans to strictly regulate high-risk AI technology
European Commission's artificial intelligence plan also promises to pump billions into R&D
4h
Europe takes on China, U.S with plan to regulate global tech. "It's not us that need to adapt to today's platforms. It's the platforms that need to adapt to Europe," European Industry Commissioner Thierry Breton said at a press conference in Brussels.
submitted by /u/ngt_ [link] [comments]
2h
Evaluating risk of cancer in patients with psoriasis, psoriatic arthritis
This observational study was a systematic review and meta-analysis that included 112 studies and examined the association between risk of cancer in patients with psoriasis or psoriatic arthritis, including the risk of specific cancers.
4h
Expert-augmented machine learning [Medical Sciences]
Machine learning is proving invaluable across disciplines. However, its success is often limited by the quality and quantity of available data, while its adoption is limited by the level of trust afforded by given models. Human vs. machine performance is commonly compared empirically to decide whether a certain task should…
20h
Fetal balloon treatment for lung-damaging birth defect works best when fetal and maternal care are highly coordinated
Researchers from The Johns Hopkins Center for Fetal Therapy report new evidence that fetuses with severe congenital diaphragmatic hernia (CDH), a rare but life-threatening, lung-damaging condition, experience a significantly high rate of success for the fetal treatment known as FETO, if they and their mothers receive coordinated and highly experienced care in the same expert setting.
4h
Findings from NASA's Juno update Jupiter water mystery
NASA's Juno mission has provided its first science results on the amount of water in Jupiter's atmosphere. Published recently in the journal Nature Astronomy, the Juno results estimate that at the equator, water makes up about 0.25% of the molecules in Jupiter's atmosphere—almost three times that of the Sun. These are also the first findings on the gas giant's abundance of water since the agency's
8h
Fish in the Sahara? Yes, in the early Holocene
Catfish and tilapia make up many of the animal remains uncovered in the Saharan environment of the Takarkori rock shelter in southwestern Libya, according to a study published Feb. 19, 2020, in the open-access journal PLOS ONE by Wim Van Neer from the the Natural History Museum in Belgium, Belgium and Savino di Lernia, Sapienza University of Rome, Italy, and colleagues.
1h
Five millimeter diameter motor is powered directly with light
Researchers at the Faculty of Physics at the University of Warsaw, with colleagues from Poland and China used liquid crystal elastomer technology to demonstrate a rotary micromotor powered with light. The 5-millimeter diameter ring, driven and controlled by a laser beam, can rotate and perform work, e.g. by rotating another element installed on the same axis.
5h
'Flapping wings' powered by the sun (video)
In ancient Greek mythology, Icarus' wax wings melted when he dared to fly too close to the sun. Now, researchers reporting in ACS Applied Materials & Interfaces have made artificial wings that are actually powered by the sun. The tiny wings, which can flap even faster than those of butterflies, could someday be used in robots or devices for solar energy harvesting, the researchers say.
5h
For The Last Time, No, A NASA Engineer Has Not Broken Physics With An Impossible Engine
submitted by /u/Futurycon [link] [comments]
6h
From obesity to liver cancer: Can we prevent the worst?
Hepatocellular carcinoma, a liver cancer linked to the presence of fat in the liver, is one of the leading causes of cancer death worldwide. Scientists (UNIGE) have discovered a protein involved in the progression of a "fatty liver" towards cancer. This protein could allow early detection of the risk of developing liver cancer and open the way to new targeted therapies. These results highlight the
6h
Functional lipid pairs as building blocks of phase-separated membranes [Biophysics and Computational Biology]
Biological membranes exhibit a great deal of compositional and phase heterogeneity due to hundreds of chemically distinct components. As a result, phase separation processes in cell membranes are extremely difficult to study, especially at the molecular level. It is currently believed that the lateral membrane heterogeneity and the formation of…
20h
Fundamental symmetry tested using antihydrogen
Nature, Published online: 19 February 2020; doi:10.1038/d41586-020-00384-y The breaking of a property of nature called charge–parity–time symmetry might explain the observed lack of antimatter in the Universe. Scientists have now hunted for such symmetry breaking using the antimatter atom antihydrogen.
5h
Future soldiers may get improved helmet padding
Army researchers and industry partners recently published a study showing how they developed new materials and manufacturing methods to create higher performing helmet padding that reduces the likelihood of head injury in combat and recreational helmets.
1h
Galaxy Cruise—Your galactic journey as a citizen scientist
The Universe is full of galaxies of various shapes; some galaxies have spiral arms and others don't. Why do galaxies show such diversity? Galaxies are thought to grow by interacting and merging with other galaxies; and the galaxy mergers may be the key process creating the variety. Why don't you explore the Universe as a citizen scientist to help unlock the secrets of galaxies?
6h
GDF11 promotes osteogenesis as opposed to MSTN, and follistatin, a MSTN/GDF11 inhibitor, increases muscle mass but weakens bone [Medical Sciences]
Growth and differentiation factor 11 (GDF11) and myostatin (MSTN) are closely related transforming growth factor β (TGF-β) family members, but their biological functions are quite distinct. While MSTN has been widely shown to inhibit muscle growth, GDF11 regulates skeletal patterning and organ development during embryogenesis. Postnatal functions of GDF11, however,…
20h
Gene expression and cell identity controlled by anaphase-promoting complex
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2034-1 WDR5 and TBP recruit anaphase-promoting complex to specific transcription start sites in mitosis, initiating a ubiquitin-dependent mechanism that preserves cell identity by linking gene expression and cell division.
5h
Gene genies: new Guardian podcast explores the tech reshaping our human identity
A year-long Guardian multimedia project investigates the scientific, philosophical and ethical impacts that gene editing technology could have on society, and asks: Whose vision of the future are we trying to create? Lindsay Poulton is head of Guardian documentaries. Max Sanderson is the Guardian's lead producer in audio. Gene editing could be one of the most interesting and relevant scientific s
8h
Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases
Effector functions of immunoglobulin G (IgG) are regulated by the composition of a glycan moiety, thus affecting activity of the immune system. Aberrant glycosylation of IgG has been observed in many diseases, but little is understood about the underlying mechanisms. We performed a genome-wide association study of IgG N-glycosylation ( N = 8090) and, using a data-driven network approach, suggeste
1h
Green chemistry of fullerene: Scientists invented an environmentally friendly way to realize organic
Scientists from the Skoltech Center for Energy Science and Technology (CEST) and the Institute for Problems of Chemical Physics of Russian Academy of Sciences have developed a novel approach for preparing thin semiconductor fullerene films. The method enables fabrication of organic electronics without using toxic organic solvents and costly vacuum technologies, thus reducing the environmental risk
5h
Growing crystals to generate random numbers
A team at the University of Glasgow has developed a novel way to generate random numbers by using the randomness inherent in crystal growth. In their paper published in the journal Matter, the group describes using chemistry to generate random numbers for use in other applications.
7h
Hackers can trick a Tesla into accelerating by 50 miles per hour
A two inch piece of tape fooled the Tesla's cameras and made the car quickly and mistakenly speed up.
15h
Hackers Stick Tape on Speed Sign, Trick Teslas Into Going Faster
That's Not a Three In a troubling experiment , researchers at security firm McAfee were able to trick two 2016 Teslas, with cruise control enabled, into driving up to 50 mph in a 35 mph zone — simply by sticking two inches of black tape over the three on the speed sign, making the vehicles think they were in an 85 mph zone. It's a scary indication that contemporary autonomous driving features mig
5h
Hans Clevers (Hubrecht I., UU) 1: Discovery and Characterization of Adult Stem Cells in the Gut
https://www.ibiology.org/development-and-stem-cells/organoids Dr. Hans Clevers provides a historical perspective on the discovery of adult stem cells in the gut, and explains how his lab developed a technique to grow from a single stem cell an organoid or mini-organ, a structure that recapitulates the normal structure of the gut. In his first talk, Dr. Hans Clevers provides a historical perspecti
13h
Hans Clevers (Hubrecht I., UU) 2: Generating Epithelial Organoids from Adult Tissue
https://www.ibiology.org/development-and-stem-cells/organoids Dr. Hans Clevers provides a historical perspective on the discovery of adult stem cells in the gut, and explains how his lab developed a technique to grow from a single stem cell an organoid or mini-organ, a structure that recapitulates the normal structure of the gut. In his first talk, Dr. Hans Clevers provides a historical perspecti
13h
Hans Clevers (Hubrecht I., UU) 3: Organoid Technology for Disease Modeling
https://www.ibiology.org/development-and-stem-cells/organoids Dr. Hans Clevers provides a historical perspective on the discovery of adult stem cells in the gut, and explains how his lab developed a technique to grow from a single stem cell an organoid or mini-organ, a structure that recapitulates the normal structure of the gut. In his first talk, Dr. Hans Clevers provides a historical perspecti
13h
Have Humans Evolved Beyond Nature—and Do We Even Need It?
Such is the extent of our dominion on Earth, that the answer to questions around whether we are still part of nature, and whether we even need some of it, rely on an understanding of what we want as Homo sapiens . And to know what we want, we need to grasp what we are. It is a huge question, but they are the best. And as a biologist, here is my humble suggestion to address it, and a personal conc
6h
Heather Couper: Broadcaster and astronomer dies at 70
She appeared on TV shows ranging from Blue Peter to The Sky At Night, as well as documentaries.
3h
High rate of extrapair paternity in a human population demonstrates diversity in human reproductive strategies
Among nonhuman species, social monogamy is rarely accompanied by complete fidelity. Evolutionary theory predicts that the rate of extrapair paternity (EPP) should vary according to socioecological conditions. In humans, however, geneticists contend that EPP is negligible and relatively invariable. This conclusion is based on a limited set of studies, almost all of which describe European-descent
1h
Higher-rank zeta functions for elliptic curves [Mathematics]
In earlier work by L.W., a nonabelian zeta function was defined for any smooth curve X over a finite field Fq and any integer n≥1 bywhere the sum is over isomorphism classes of Fq-rational semistable vector bundles V of rank n on X with degree divisible by n. This function,…
20h
Historical comparison of gender inequality in scientific careers across countries and disciplines [Social Sciences]
There is extensive, yet fragmented, evidence of gender differences in academia suggesting that women are underrepresented in most scientific disciplines and publish fewer articles throughout a career, and their work acquires fewer citations. Here, we offer a comprehensive picture of longitudinal gender differences in performance through a bibliometric analysis of…
20h
Homeless in Siberia: Surviving the Winter
Alexey Malgavko, a photojournalist working with Reuters, spent time this winter among the homeless population of the Russian city of Omsk. Life is extremely difficult for those living rough in a city where wintertime-low temperatures can reach –22 degrees Fahrenheit (–30 Celsius) at night. Many survive the cold by finding or making shelters along industrial heating pipes that run through the city
2h
How Are Exoplanets Discovered?
The exoplanets outside our solar system are practically invisible. So, how do astronomers find them?
18h
How does long-term quality of life, patient satisfaction compare for appendicitis treatments?
Researchers compared long-term quality of life and patient satisfaction among those patients who were treated with antibiotics or who had their appendix removed for uncomplicated acute appendicitis. Evidence in recent years has indicated antibiotic treatment is a safe and efficient alternative to appendectomy.
4h
How genetic testing is helping scientists save animals from disease and illegal hunting
DNA testing kits for humans and their pets are a growing business. The draw for consumers ranges from understanding why their dog looks like a Labrador but acts like a German Shepherd, or what diseases they might be prone to.
6h
How overseas stag parties are hurting the environment
About half the flights young men take each year are for stag dos – and that generates a lot of emissions.
9h
How plant cells sense the outside world through hydrogen peroxide
Nature, Published online: 19 February 2020; doi:10.1038/d41586-020-00403-y The discovery of a sensor that detects hydrogen peroxide at the surface of a cell provides insights into the mechanisms by which plant cells perceive and respond to environmental stress.
5h
How the Pink Princess and the Pink Congo Scam Flourished Online
The pink princess philodendron is the ultimate Instagram plant, with three-digit price tags to match. The following it cultivated was also ripe for deception.
9h
How to deflect an asteroid
MIT engineers devise a decision map to identify the best mission type to deflect an incoming asteroid.
2h
How to keep your bones strong—and even make them stronger
Bones are alive—and they require maintenance work. (Deposit Photos/) For February, we're focusing on the body parts that shape us, oxygenate us, and power us as we take long walks on the beach. Bony bonafide bones. These skeletal building blocks inspire curiosity and spark fear in different folks—we hope our stories, covering everything from surgeries and supplements to good old-fashioned boning,
8h
How to Maximize Your Workout with Push-Pull Strength Training
Do you want a flexible, balanced, easy-to-remember workout that doesn't require spending all day at the gym? Push-pull strength training is for you! — Read more on ScientificAmerican.com
6h
How to Murder Harry Potter
When Rachel was growing up in upstate New York, she was what she calls "a creepy girl child"—one prone to wild crying jags that often baffled her mother. Rachel was also, like something to close to all American 13-year-olds in the early aughts, an ardent fan of Harry Potter. She read the books, obviously. And once she had exhausted those, she turned to the internet, where she found a seemingly en
3h
Humanity will need to make some drastic changes if it wants to keep the 'good life' going
submitted by /u/jcaraway [link] [comments]
8h
Hunt through satellite images of Earth with an AI search engine
This AI search engine takes one tenth of a second to search more than 2 billion satellite images, identifying similar natural or built features such as forests or military bases
2h
Hurricanes fertilize mangrove forests in the Gulf of Mexico (Florida Everglades, USA) [Ecology]
Hurricanes are recurring high-energy disturbances in coastal regions that change community structure and function of mangrove wetlands. However, most of the studies assessing hurricane impacts on mangroves have focused on negative effects without considering the positive influence of hurricane-induced sediment deposition and associated nutrient fertilization on mangrove productivity and resilience
20h
Hurricanes lay waste to mangroves, but they also help them flourish
The same hurricanes that batter mangroves also help these forests withstand sea level rise and deliver nutrients that allow the trees to bounce back after the storm. (Edward Castañeda-Moya/) On September 10, 2017, Hurricane Irma made landfall in southwestern Florida as a category 3 storm with 115 mile-per-hour winds that swept up the coast. Along the way, it plowed through the mangrove forests in
5h
Hydrogen peroxide sensor HPCA1 is an LRR receptor kinase in Arabidopsis
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2032-3 HPCA1, a member of a previously uncharacterized subfamily of leucine-rich-repeat receptor-like kinases, is the hydrogen-peroxide sensor at the plasma membrane in Arabidopsis.
5h
ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2015-4 Tumour-infiltrating group 2 innate lymphoid cells prime CD8+ T cells and amplify the anti-tumour effects of PD-1 blockade in pancreatic ductal adenocarcinoma.
5h
Image of the Day: Flock in the Night
The National Weather Service's radar in Key West captures a spectacular moment in bird migration.
8h
Impact of Lasers on Warfare
4 US Navy ships are now equipped with lasers able to destroy small boats and drones. It's not hard to imagine more powerful ones having enough range to take out missiles. The greatest sci-fi cliche is set to become reality with enormous implications for warfare and foreign policy. The laser's biggest advantage is the extremely low cost of each shot. The missiles of Israel's Iron Dome system each
14h
Improved access to Midwifery Units is urgently needed, says new study
A high number of pregnant women in England cannot access the maternity care most appropriate for them, according to a new study, which could be costing the NHS millions of pounds a year. The research, which is published in the BMJ Open, reviewed NHS maternity services in different areas of England and identified a number of key factors that limit the availability and use of Midwifery Units, (home-
5h
Improving assessments of an endangered lion population in India
An alternative method for monitoring endangered lions in India could improve estimates of their abundance and help inform conservation policy and management decisions. Keshab Gogoi and colleagues at the Wildlife Institute of India present their findings in the open-access journal PLOS ONE on Feb. 19, 2020.
1h
Improving innovation: Assessing the environmental impacts of emerging technology
Although many new technologies offer the promise to improve human welfare, they can also produce unintended environmental consequences. And while applying the principles of life cycle assessment (LCA) early in technology development can provide important insights about how to avoid damage to the environment, existing methods focus on products or processes that are already commercially established.
1h
Improving the electrical and mechanical properties of carbon-nanotube-based fibers
The Lyding Group recently developed a technique that can be used to build carbon-nanotube-based fibers by creating chemical crosslinks. The technique improves the electrical and mechanical properties of these materials.
12h
In-Depth Look At The Future Of Wireless EV- Charging
submitted by /u/BENshakalaka [link] [comments]
19h
Infection in Advanced Chronic Kidney Disease and Subsequent Adverse Outcomes after Dialysis Initiation: A Nationwide Cohort Study
Scientific Reports, Published online: 19 February 2020; doi:10.1038/s41598-020-59794-7
11h
Inhibition of TGF-β signalling in combination with nal-IRI plus 5-Fluorouracil/Leucovorin suppresses invasion and prolongs survival in pancreatic tumour mouse models
Scientific Reports, Published online: 19 February 2020; doi:10.1038/s41598-020-59893-5
11h
Insignificant effect of Arctic amplification on the amplitude of midlatitude atmospheric waves
Whether Arctic amplification has contributed to a wavier circulation and more frequent extreme weather in midlatitudes remains an open question. For two to three decades starting from the mid-1980s, accelerated Arctic warming and a reduced meridional near-surface temperature gradient coincided with a wavier circulation. However, waviness remains largely unchanged in model simulations featuring st
1h
Insurance industry CEO pay tied more closely to firm performance since financial crisis
Compensation packages for insurance industry CEOs changed in the wake of the 2008 financial crisis, with bonuses reduced and other incentives increased, according to a new study from FIU Business.
6h
Interfering MSN-NONO complex-activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer
Triple-negative breast cancer (TNBC) is life-threatening because of limited therapies and lack of effective therapeutic targets. Here, we found that moesin (MSN) was significantly overexpressed in TNBC compared with other subtypes of breast cancer and was positively correlated with poor overall survival. However, little is known about the regulatory mechanisms of MSN in TNBC. We found that MSN si
1h
Investigating Medicaid expansion's association with insurance status, diagnosis, treatment among patients with cancer
More than 925,000 adults in the National Cancer Database with a new diagnosis of invasive breast, colon or lung cancer were included in this observational study that examined how Medicaid expansion under the Patient Protection and Affordable Care Act (ACA) was associated with insurance status, cancer stage at diagnosis and timely treatment.
4h
Investigation of the fine structure of antihydrogen
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2006-5 Precision measurements of the 1S–2P transition in antihydrogen that take into account the standard Zeeman and hyperfine effects confirm the predictions of quantum electrodynamics.
5h
IRE1{alpha} kinase-mediated unconventional protein secretion rescues misfolded CFTR and pendrin
The most prevalent pathogenic mutations in the CFTR ( F508 ) and SLC26A4 /pendrin ( p.H723R ), which cause cystic fibrosis and congenital hearing loss, respectively, evoke protein misfolding and subsequent defects in their cell surface trafficking. Here, we report that activation of the IRE1α kinase pathway can rescue the cell surface expression of F508-CFTR and p.H723R-pendrin through a Golgi-in
1h
Is the Mesentery an Organ?
Watch surgeon Calvin Coffey deliver a TEDx talk on his recent discovery that the large abdominal tissue is a single, coordinated structure.
3h
Japan Lets Cruise Passengers Walk Free. Is That Safe?
As a two-week quarantine over a coronavirus outbreak ended, experts expressed alarm over the protocols on the ship, which now has 621 confirmed infections.
4h
Jet stream not getting 'wavier' despite Arctic warming
Rapid Arctic warming has not led to a "wavier" jet stream around the mid-latitudes in recent decades, pioneering new research has shown.
2h
Keeping it simple — Synthesizing useful organic compounds now made easier and cheaper
Organic boronic acids are widely used as starting material in the synthesis of various useful chemicals. But, some organic boronic acids are unstable and lead to unwanted 'side reactions.' Thus, they need to be protected with a functional group, which needs to be removed afterwards. A research team from Tokyo University of Science recently uncovered how this unnecessary step (removal of the functi
5h
Kilometers of "Dark Cable" Form the Newest Seismic Sensors
Fiber-optic cables stretching below cities, through glaciers and along the seafloor could record earthquakes and more — Read more on ScientificAmerican.com
9h
LATS kinase-mediated CTCF phosphorylation and selective loss of genomic binding
Chromatin topological organization is instrumental in gene transcription. Gene-enhancer interactions are accommodated in the same CTCF-mediated insulated neighborhoods. However, it remains poorly understood whether and how the 3D genome architecture is dynamically restructured by external signals. Here, we report that LATS kinases phosphorylated CTCF in the zinc finger (ZF) linkers and disabled i
1h
Lensless on-chip microscopy platform shows slides in full view
Guoan Zheng, a University of Connecticut professor of biomedical engineering, recently published his findings on a successful demonstration of a lensless on-chip microscopy platform that eliminates several of the most common problems with conventional optical microscopy and provides a low-cost option for the diagnosis of disease.
4h
Ljudvågsanalys lär oss mer om revolutioner
När någonting kallas för en revolution backas det sällan upp med data – oavsett om det handlar om teknik, musik eller demokrati. Nu har forskare från bland annat Imperial College i London föresatt sig att ändra på det. De har utvecklat en ny mjukvara som kan analysera stora datamängder från en period och upptäcka tillfällen med ovanligt snabb förändring – som när vers blir refräng i musik, vilket
6h
Local lattice distortions and dynamics in extremely overdoped superconducting YSr2Cu2.75Mo0.25O7.54 [Physics]
A common characteristic of many "overdoped" cuprates prepared with high-pressure oxygen is Tc values ≥ 50 K that often exceed that of optimally doped parent compounds, despite O stoichiometries that place the materials at the edge or outside of the conventional boundary between superconducting and normal Fermi liquid states. X-ray…
20h
Machine learning identifies personalized brain networks in children
Machine learning is helping Penn Medicine researchers identify the size and shape of brain networks in individual children, which may be useful for understanding psychiatric disorders. In a new study published in the journal Neuron, a multidisciplinary team showed how brain networks unique to each child can predict cognition. The study is the first to show that functional neuroanatomy can vary gre
4h
Madame Yale Made a Fortune With the 19th Century's Version of Goop
A century before today's celebrity health gurus, an American businesswoman was a beauty with a brand
6h
Making new online accounts is the ultimate privacy power play
Aaaand… delete. (BestPhotoStudio via Depositphotos/) If you've spent any time on the web or on a smartphone in the last few years, chances are that advertisers and tech firms have amassed a substantial amount of information about you, including your life, habits, and interests. There are multiple ways you can protect your privacy from within your various accounts (including these guides on how
3h
Maternal obesity linked to ADHD and behavioral problems in children, NIH study suggests
Maternal obesity may increase a child's risk for attention-deficit hyperactivity disorder (ADHD), according to an analysis by researchers from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health.
3h
Measurement of the quantum geometric tensor and of the anomalous Hall drift
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-1989-2 Direct measurement of the Berry curvature and the quantum metric of photonic modes in a high-finesse planar microcavity is achieved, enabling quantitative prediction of the independently measured anomalous Hall drift.
5h
Measuring a dynamical topological order parameter in quantum walks
Nonequilibrium dynamical processes are central in many quantum technological contexts. However, it has remained a key challenge to identify concepts for their characterization and classification, as the resulting quantum states purposely defy a description in terms of equilibrium statistical physics in order to realize states not accessible by conventional means. Scientists have now achieved a cha
5h
Meet the Virtual, Anime Camgirl the Internet's Most Toxic Men Are Obsessed With
Waifu Guys Earlier this month, a virtual, anime-inspired avatar named Melody started hosting sexually explicit livestreams — a cartoony recreation of how many adult entertainers and sex workers make money online. Since then, Wired reports that Projekt Melody has amassed a following of nearly 20,000 horny fans on the adult streaming site Chaturbate and has an even bigger audience on social media.
1h
Mesentary, Tissue or Organ?
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3h
Methane emitted by humans vastly underestimated, researchers find
Methane is a powerful greenhouse gas and large contributor to global warming. Methane emissions to the atmosphere have increased by approximately 150 percent over the past three centuries, but it has been difficult for researchers to determine exactly where these emissions originate; heat-trapping gases like methane can be emitted naturally, as well as from human activity.
5h
Microbial feedbacks optimize ocean iron availability [Earth, Atmospheric, and Planetary Sciences]
Iron is the limiting factor for biological production over a large fraction of the surface ocean because free iron is rapidly scavenged or precipitated under aerobic conditions. Standing stocks of dissolved iron are maintained by association with organic molecules (ligands) produced by biological processes. We hypothesize a positive feedback between…
20h
MIT Engineers devise the best way to deflect an incoming planet-killer asteroid. Their decision method takes into account an asteroid's mass and momentum, its proximity to a gravitational keyhole, and the amount of warning time that scientists have of an impending collision.
submitted by /u/ngt_ [link] [comments]
6h
MIT Proposes New Plans for Deflecting Killer Asteroids
Corner Pocket A team of MIT scientists has a new plan to prevent cataclysmic asteroid impacts — and it boils down to a precise game of cosmic billiards. The scientists suggest that they could nudge killer asteroids off course well in advance, rather than hoping that some last-minute attempt — think the sci-fi trope of launching nukes into space — will pan out. Scouting Ahead If an asteroid is spo
4h
Mixed-signal hardware security thwarts powerful electromagnetic attacks
A Purdue University team developed technology to use mixed-signal circuits to embed critical information that is suppressed at a lower level.
15h
Motsättningar mellan matteboken och digitala läromedel
Digitala läromedel i skolan är tänkta att skapa mer tid för lärarna och individuell kunskapsutveckling för eleverna. Men användandet leder inte automatiskt till förbättringar utan skapar också tydliga motsättningar, visar pedagogisk forskning. Den tryckta läroboken som tidigare har varit en av de primära resurserna i klassrummet för att lära sig matematik, samt vägledande i hur ämnet ska läras ut
7h
MRI findings predict shoulder stiffness for rotator cuff tears
Two MRI findings–joint capsule edema and thickness at the axillary recess, specifically–proved useful in predicting stiff shoulder in patients with small to large (< 5 cm) full-thickness rotator cuff tears, according to an ahead-of-print article in the May issue of the American Journal of Roentgenology (AJR). This study is important because it is the first to highlight joint capsule abnormality
4h
Multiple lipid binding sites determine the affinity of PH domains for phosphoinositide-containing membranes
Association of peripheral proteins with lipid bilayers regulates membrane signaling and dynamics. Pleckstrin homology (PH) domains bind to phosphatidylinositol phosphate (PIP) molecules in membranes. The effects of local PIP enrichment on the interaction of PH domains with membranes is unclear. Molecular dynamics simulations allow estimation of the binding energy of GRP1 PH domain to PIP 3 -conta
1h
Mussels 'cooked alive' in balmy New Zealand ocean
Up to half a million mussels were effectively cooked in the wild in unusually balmy waters on the New Zealand coast in a massive "die-off" that marine experts have linked to climate change.
12h
Mystisk radiostøj er stadig en gåde: Eksperter tog tomhændede fra Bornholm
Energistyrelsen har været på Bornholm for at finde mystisk støjkilde, som generer bredbånd og wifi. Besøget gav dog ikke noget resultat.
5h
Nanomaterials derived from cellulose could make renewable energy cheaper
Nature isn't always generous with its secrets. That's why some researchers look into unusual places for solutions to our toughest challenges, from powerful antibiotics hiding in the guts of tiny worms, to swift robots inspired by bats.
8h
Neanderthal Skeleton Find Supports Idea of Intentional Burials
Microscopic plant remnants found near the bones indicate that the ancient humans practiced burying rituals, but the archaeological field is not in full agreement.
21 min
Neighborhood features and one's genetic makeup interact to affect cognitive function
Few studies have examined how the neighborhood's physical environment relates to cognition in older adults. Researchers categorized 4,716 individuals by apolipoprotein E (APOE) genotype — a genetic risk factor for Alzheimer's disease (AD) to determine if there are cognitive benefits of living in neighborhoods with greater access to social, walking and retail destinations. Results showed that the
6h
Neuroscientist Phil Haydon Sets Sail to Talk About Epilepsy
After an accident as a teenager, he developed the disorder. He then studied the brain to better understand his own seizures, and now plans to sail around the world to show others with the condition how to push their limits.
47 min
New 3D chirality discovered and synthetically assembled
Multi-layer 3D chirality of C2-symmetry has been revealed and enantioselectively synthesized. This chirality is a new addition to the family of known chirality consisting of element central, axial/helical, spiro and double planar types. In this 3D chiral framework, the top and bottom layers restrict each other from free bond rotation. These chiral 3D molecules showed strong luminescence of various
6h
New class of enzymes could lead to bespoke diets, therapeutics
Everyone seems to have an opinion about which foods to eat or avoid, how to lose weight (and keep it off!), and which superfood to horde. But there's a better place to search for health secrets than in a tropical berry: the human gut.
8h
New engine would use an explosion to blast spacecraft into orbit
A new mathematical model describes how a type of rocket engine known as a rotating detonation engine would work, researchers report. The new engine promises to make rockets not only more fuel-efficient but also more lightweight and less complicated to construct. There's just one problem: Right now this engine is too unpredictable to be used in an actual rocket. With the new model, engineers can,
6h
New machine learning method could supercharge battery development for electric vehicles
New machine learning method from Stanford, with Toyota and MIT researchers, has slashed battery testing times — a key barrier to longer-lasting, faster-charging batteries for electric vehicles — by nearly fifteenfold.
2h
New mathematical model reveals how major groups arise in evolution
Researchers at Uppsala University and the University of Leeds presents a new mathematical model of patterns of diversity in the fossil record, which offers a solution to Darwin's "abominable mystery" and strengthens our understanding of how modern groups originate. The research is published in the journal Science Advances.
1h
New mechanism involved in senescence modulates inflammation, response to immunotherapy
Wistar scientists discovered a novel pathway that enables detection of DNA in the cytoplasm and triggers inflammation and cellular senescence.
10h
New Rocket Design Is Powered by a Ring of Literal Explosions
Exploding Rocket Researchers at the University of Washington have dreamed up a new type of rocket they call a "rotating detonation engine" that they say could allow for the construction of far lighter and fuel-efficient spacecraft. The catch: it's powered by literal explosions, which are difficult to control — for obvious reasons. "A rotating detonation engine takes a different approach to how it
3h
New study finds cellular immunotherapy treatment associated with improved quality of life
Adult lymphoma patients whose disease was effectively treated with chimeric antigen receptor T-cell (CAR-T) therapy showed marked improvement on a variety of self-reported quality of life measures, according to a study published today in Blood Advances. The study offers evidence that CAR-T may not only extend cancer patients' survival, but also improve their quality of life after treatment.
3h
New study results consistent with dog domestication during ice age
Analysis of Paleolithic-era teeth from a 28,500-year-old fossil site in the Czech Republic provides supporting evidence for two groups of canids — one dog-like and the other wolf-like – with differing diets, which is consistent with the early domestication of dogs.
4h
New type of heart valve may be the only replacement a child needs
Current prosthetic heart valves for children with congenital heart disease are fixed in size, requiring repeated open-heart surgeries during childhood to replace the valve with a larger version. But a surprising new design created at Boston Children's Hospital could allow children to keep the same prosthetic valve until adulthood, and could also benefit adults with heart valve defects. The new dev
1h
Nitrifier adaptation to low energy flux controls inventory of reduced nitrogen in the dark ocean [Ecology]
Ammonia oxidation to nitrite and its subsequent oxidation to nitrate provides energy to the two populations of nitrifying chemoautotrophs in the energy-starved dark ocean, driving a coupling between reduced inorganic nitrogen (N) pools and production of new organic carbon (C) in the dark ocean. However, the relationship between the flux…
20h
No need to give up on crowded cities: We can make density so much better
The idea that we should decentralize our population has come up many times in Australia. Recently, the National Farmers' Federation president pushed the notion, calling for a shift to the regions. And the premise is this: city living is unpleasant. Roads are jammed, housing is expensive and it's all so much nicer out in the country. We need to "spread out."
6h
noise-tolerant single photon sensitive three-dimensional imager
submitted by /u/quantumcat1984 [link] [comments]
4h
Noninvasive muscle activity imaging using magnetography [Neuroscience]
A spectroscopic paradigm has been developed that allows the magnetic field emissions generated by the electrical activity in the human body to be imaged in real time. The growing significance of imaging modalities in biology is evident by the almost exponential increase of their use in research, from the molecular…
20h
Nu kan forældre låse TikTok-appen. 'Falsk tryghed', lyder kritik
Børn kan let hacke app-lås, lyder kritik fra ekspert.
33 min
Nya kolesterolsänkande riktlinjer kan stå svensk sjukvård dyrt
Ett införande av nya riktlinjer för kolesterolsänkande behandling från europeiska expertorganisationer skulle drastiskt öka kostnaden för hälso- och sjukvården, visar en simuleringsstudie från Karolinska institutet. Detta skulle innebära en bred användning av en ny typ av kolesterolsänkande terapi, så kallade PCSK9-hämmare. – PCSK9-hämmare är helt klart väldigt effektiva vid behandling av blodfet
4h
Once cyber grooming starts, the first five days are critical
Cybercriminal phenomena seem to have caught society and authorities unprepared and off guard. As a quick response to explain the phenomena, research has tried to transfer existing theories and solutions about crime and deviant human behavior from the physical world to cyberspace.
5h
Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination [Neuroscience]
The brain's endogenous capacity to restore damaged myelin deteriorates during the course of demyelinating disorders. Currently, no treatment options are available to establish remyelination. Chronic demyelination leads to damaged axons and irreversible destruction of the central nervous system (CNS). We identified two promising therapeutic candidates which enhance remyelination: oncostatin M…
20h
On-device lead sequestration for perovskite solar cells
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2001-x Using lead-absorbing materials to coat the front and back of perovskite solar cells can prevent lead leaching from damaged devices, without affecting the device performance or long-term operation stability.
5h
One drug, many diseases
It seems too good to be true: a single drug that could treat humanity's worst afflictions, including atherosclerosis, cancer, Alzheimer's, Parkinson's and arthritis. All of these diseases have one thing in common—they involve an inflammatory protein called NLRP3. Now, biotech start-ups and pharmaceutical companies are racing to develop drugs that inhibit the function of this protein, according to
4h
Ordkrig efter kvælstofbrøler: Universitet afviser regnefejl
PLUS. Aarhus Universitet erkender at have lavet en fejl i forbindelse med estimatet af den danske kvælstofudledning, men klager over, at miljøministeriet omtaler det som en regnefejl. Ministeriet mangler »forståelse og respekt« for forskernes arbejde, lyder det.
16h
Palaeontologists identify new Jurassic amphibian
A group of Russian and German palaeontologists have described a previously unknown genus and species of prehistoric salamanders. The new amphibian is named Egoria malashichevi—in honor of Yegor Malashichev a talented scientist and associate professor of the Department of Vertebrate Zoology at St Petersburg University, who passed away at the end of 2018.
2h
Parenting elective lets physicians spend more time with their babies
A novel, four-week parenting rotation designed for pediatric residents has dramatically increased the amount of time resident parents can spend at home with their babies, according to a study by researchers at the University of Colorado Anschutz Medical Campus.
5h
Parlor Trick Keeps Monorails on Track
Originally published in January 1914 — Read more on ScientificAmerican.com
9h
Pentagon to Adopt Detailed Principles for Using AI
submitted by /u/Arzu_1982 [link] [comments]
34 min
People who eat a big breakfast may burn twice as many calories
Eating a big breakfast rather than a large dinner may prevent obesity and high blood sugar, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.
6h
Perth Pictish find offers glimpse into Scotland's warrior past
Archaeologists have carefully recreated images of a figure on a Pictish stone, discovered during the construction of a road in 2017, with the details uncovered offering new insights into Scotland's warrior past.
7h
Phage liquid crystalline droplets form occlusive sheaths that encapsulate and protect infectious rod-shaped bacteria [Biophysics and Computational Biology]
The opportunistic pathogen Pseudomonas aeruginosa is a major cause of antibiotic-tolerant infections in humans. P. aeruginosa evades antibiotics in bacterial biofilms by up-regulating expression of a symbiotic filamentous inoviral prophage, Pf4. We investigated the mechanism of phage-mediated antibiotic tolerance using biochemical reconstitution combined with structural biology and high-resolution
20h
Phenotypic plasticity of carbon fixation stimulates cyanobacterial blooms at elevated CO2
Although phenotypic plasticity is a widespread phenomenon, its implications for species responses to climate change are not well understood. For example, toxic cyanobacteria can form dense surface blooms threatening water quality in many eutrophic lakes, yet a theoretical framework to predict how phenotypic plasticity affects bloom development at elevated p CO 2 is still lacking. We measured phen
1h
Phone App Unlocks Rental Car, Then Strands Driver in California Boondocks
It was the perfect storm: A technology reporter rents a car-share Toyota hybrid that's accessed and unlocked by the renter's smartphone and an onboard modem. Rented in California, no less, which is ground zero for technology. Reporter and partner then drive into a remote coastal area, but still in California, hike to the beach, return, and the app won't unlock the car. Reporter calls carshare com
2h
Physicists Come Closer to Answering Question of Antimatter's Scarcity
Researchers have confirmed a long-predicted key similarity between hydrogen and antihydrogen — Read more on ScientificAmerican.com
5h
Physicists Come Closer to Answering Question of Antimatter's Scarcity
Researchers have confirmed a long-predicted key similarity between hydrogen and antihydrogen — Read more on ScientificAmerican.com
5h
Physicists Take Their Closest Look Yet at an Antimatter Atom
Scientists at CERN found a way to trap hydrogen's mirror twin, antihydrogen, long enough to study it in greater detail than ever before.
5h
Plantwatch: how urban trees and hedges help cut air pollution
The plants trap polluting particles like natural air filters, and protect against flooding, too Hedges and trees in towns and cities are more than just attractive, they can behave like natural air filters, trapping traffic pollution made up of dangerous microscopic particles blamed for a range of serious health problems, ranging from heart disease, asthma and strokes to diabetes, obesity and deme
12h
Podcast: Improving battery charging, and harnessing energy from the air
Nature, Published online: 19 February 2020; doi:10.1038/d41586-020-00482-x Listen to the latest science news, with Nick Howe and Benjamin Thompson.
5h
PR-branschen skolar politiker i näringslivstänk
Politiker som roterat mellan politik och PR förändrar sina värderingar i grunden, enligt en intervjustudie av 25 politiker. – De socialiseras in i marknadens logik, säger Anna Tyllström, forskare vid Institutet för framtidsstudier. Det blir allt vanligare att politiker går från politik till PR- och lobbyuppdrag. Åtskilliga återvänder också till politiken. Men inte utan att förändras. Efter valet
7h
Predicting 50,000 years of bird migrations
Neither wind, nor rain—nor massive sheets of ice—have kept Earth's birds from their appointed rounds of migrating to better climes, according to a new study.
5h
Predicting clinical benefit of immunotherapy by antigenic or functional mutations affecting tumour immunogenicity
Nature Communications, Published online: 19 February 2020; doi:10.1038/s41467-020-14562-z Predicting response to cancer immunotherapy is still a challenge. Here, the authors show that their method of predicting MHC-binding peptides, combined with profiling anti-immunogenic mutations, can better predict the clinical benefit of immunotherapy.
10h
Primary cell wall inspired micro containers as a step towards a synthetic plant cell
Nature Communications, Published online: 19 February 2020; doi:10.1038/s41467-020-14718-x Assembling synthetic plant cell is difficult due to the presence of primary cell wall. Here, the authors describe the assembly of lipid-containing bodies that can be coated with cellulose and pectin, and show how these so-called plantosomes can be manipulated by changing surrounding milieu.
10h
Progress or pinkwashing: Who benefits from women-focused capital funds?
An increase in the number of women-focused capital funds promises to help address gender gaps in the provision of financial capital.
6h
Publisher Correction: Frequency and Clinical Associating Factors of Valvular Heart Disease in Asymptomatic Korean Adults
Scientific Reports, Published online: 19 February 2020; doi:10.1038/s41598-020-58889-5
11h
Publisher Correction: Integrated exome and RNA sequencing of dedifferentiated liposarcoma
Nature Communications, Published online: 19 February 2020; doi:10.1038/s41467-020-14680-8
10h
Racial Inequalities in Housing Extend to Flood Buyout Programs
Whiter, wealthier communities disproportionately benefit from government programs to purchase flood-damaged homes — Read more on ScientificAmerican.com
3h
Rainbow Proof Shows Graphs Have Uniform Parts
On January 8, three mathematicians posted a proof of a nearly 60-year-old problem in combinatorics called Ringel's conjecture. Roughly speaking, it predicts that graphs — Tinkertoy-like constructions of dots and lines — can be perfectly built out of identical smaller parts. Mathematicians are excited that the new proof finds it's true. "A big reason for happiness is that this solves a very old co
6h
Rambøll: Elektrofuels kan blive god businesscase for Grønland
Rådgiveren vil nu undersøge potentialet for a bruge overskydende vandkraft og CO2 fra et kommende affaldsenergianlæg i Nuuk til fabrikation af metanol
6h
Random gene pulsing generates patterns of life
A team of Cambridge scientists working on the intersection between biology and computation has found that random gene activity helps patterns form during development of a model multicellular system.
10h
Real-time frequency-encoded spatiotemporal focusing through scattering media using a programmable 2D ultrafine optical frequency comb
Optical wavefront shaping is a powerful tool for controlling photons in strongly scattering media. Its speed, however, has been the bottleneck for in vivo applications. Moreover, unlike spatial focusing, temporal focusing from a continuous-wave source has rarely been exploited yet is highly desired for nonlinear photonics. Here, we present a novel real-time frequency-encoded spatiotemporal (FEST)
1h
Receiving the news of Down syndrome in the era of prenatal testing
Most of the mothers of a child with Down Syndrome born in the Netherlands between 2010-16 have consciously chosen not to have prenatal testing. This may be considered as an informed choice, as the majority of these mothers felt that a child with DS was welcome in their family.
19 min
Reducing noise below the sound of silence
Researchers manipulate quantum light with telling effect.
2h
Regionsrådsformand indleder dialog om serviceforringelse ved ny lægevagtsaftale
Regionsrådformand i Nordjylland er gået i dialog med tre borgmestre om, hvordan borgere kan kompenseres for de serviceforringelser, den nye lægevagtsaftale medfører.
12h
Reply to Vargas and Farhat: Mycobacterium tuberculosis glpK mutants in human tuberculosis [Letters (Online Only)]
We thank Vargas and Farhat (1) for their analyses confirming that reversible glpK frameshifts are common within human Mycobacterium tuberculosis infections. In their thoughtful comments they suggest that additional forces, other than antibiotic pressure, may contribute to the emergence of these mutants. We agree that the mechanisms by which glpK…
16 min
Reporting the facts on indigenous STIs
Young Aboriginal and Torres Strait Islander people are being discouraged from seeking medical help due to public assumptions that sexually transmissible infections (STIs) are the result of sexual abuse.
5h
Research identifies barriers to development of seawater electrolysis technologies
Researchers at the University Of Liverpool, in collaboration with NUI Galway and TU Berlin, have identified the key technological and scientific challenges of producing hydrogen through seawater electrolysis.
5h
Research shows the way to more efficient EPO production
EPO, an important drug for treating anemia, can now be produced in higher quantities and with better quality in mammalian cells designed using CRISPR.
4h
Researchers discover new mechanism for the coexistence of species
Researchers from AMOLF (Amsterdam, the Netherlands) and Harvard University (USA) show how the ability of organisms to move around plays a role in stabilizing ecosystems. In their paper published Feb. 19, 2020, in Nature, they describe how the competition between 'movers' and 'growers' leads to a balance in which both types of bacteria can continue to exist alongside each other.
4h
Researchers have created an "EpiPen" for spinal cord injuries that can potentially prevent paralysis. Injecting specially designed nanoparticles immediately after the injury can stop the body's immune system from forming a scar that blocks the regeneration of the spinal cord's nerve cells.
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34 min
Researchers Tape Speed Limit Sign to Make Teslas Accelerate to 85 MPH
The future of driving is not driving; at least that's what companies like Tesla think. Elon Musk's electric car company has focused on aggressively deploying self-driving technology in its cars, but as we've seen before, Autopilot isn't perfect. A team of security researchers from McAfee has managed to trick Tesla vehicles into speeding up by 50 miles per hour with a little bit of electrical tape
2h
Responses to "Cancer Industry: Hype vs. Reality"
Readers critique a journalist's critique of cancer medicine. — Read more on ScientificAmerican.com
1h
Responsiveness of various reservoir species to oral rabies vaccination correlates with differences in vaccine uptake of mucosa associated lymphoid tissues
Scientific Reports, Published online: 19 February 2020; doi:10.1038/s41598-020-59719-4
11h
Rice boosts 'internet of things' security — again
Rice University engineers develop a new type of security system for the 'internet of things.' The system leverages on-chip power management to greatly complicate breaching a device to break into a network.
17h
Right place, right time
Harvard researchers have discovered a new mechanism for how the brain and its arteries communicate to supply blood to areas of heightened neural activity. The findings enable new avenues of study into the role of this process in neurological diseases.
4h
Rising water raises climate change fears in the Great Lakes
Record high levels in Lake Michigan have prompted dark mutterings about global warming
10h
Risk för spridd njurcancer bedöms med DNA-markör
Det är möjligt att förutsäga risken för att njurcancer ska spridas utanför njuren genom att analysera skillnader i så kallad DNA-metylering i tumören vid diagnos. Det visar en ny avhandling vid Umeå universitet. – Ett framtida mål är att vidareutveckla de modeller vi har skapat för att kunna selektera patienterna med hög risk för tumörspridning. Nya behandlingsalternativ för patienter med hög ris
7h
Robots are not the job killers we all feared
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34 min
Scientists develop more accurate stem-cell model of early developing mouse embryo
Scientists from the Hubrecht Institute (KNAW) and the University of Cambridge (UK) have managed to generate complex embryo-like structures from mouse embryonic stem cells. These structures, called gastruloids, can now for the first time grow somites, the blocks of tissue that later develop into the vertebrae and muscles of the embryo. This model system, published in Nature on Feb. 19, can be used
4h
Scientists develop safer lead-based perovskite solar cell
Researchers at Northern Illinois University and the US Department of Energy's (DOE) National Renewable Energy Laboratory are reporting today (Feb. 19) in the journal Nature on a potential breakthrough in the development of hybrid perovskite solar cells. The scientists developed a technique to sequester the lead used to make perovskite solar cells and minimize potential toxic leakage.
35 min
Scientists Scanned Brains of Bullies and Found Something Grim
An international team of neuroscientists scanned the brains of lifelong bullies and found something grim: Bullies' brains appear to be physically smaller than other brains. "Our findings support the idea that, for the small proportion of individuals with life-course-persistent antisocial behaviour, there may be differences in their brain structure that make it difficult for them to develop social
52 min
Selective loading and processing of prespacers for precise CRISPR adaptation
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2018-1 Cas1–Cas2 selects precursor prespacers from DNA fragments in a length- and PAM-sequence-dependent manner, and these precursors are trimmed by DnaQ exonucleases to enable integration into the CRISPR locus in the correct orientation.
5h
Sensory neuron-derived NaV1.7 contributes to dorsal horn neuron excitability
Expression of the voltage-gated sodium channel Na V 1.7 in sensory neurons is required for pain sensation. We examined the role of Na V 1.7 in the dorsal horn of the spinal cord using an epitope-tagged Na V 1.7 knock-in mouse. Immuno–electron microscopy showed the presence of Na V 1.7 in dendrites of superficial dorsal horn neurons, despite the absence of mRNA. Rhizotomy of L5 afferent nerves low
1h
Sequence and structural determinants of ligand-dependent alternating access of a MATE transporter [Biophysics and Computational Biology]
Multidrug and toxic compound extrusion (MATE) transporters are ubiquitous ion-coupled antiporters that extrude structurally and chemically dissimilar cytotoxic compounds and have been implicated in conferring multidrug resistance. Here, we integrate double electron–electron resonance (DEER) with functional assays and site-directed mutagenesis of conserved residues to illuminate principles of ligan
16 min
Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke [Neuroscience]
Apoptosis and necroptosis are two regulated cell death mechanisms; however, the interaction between these cell death pathways in vivo is unclear. Here we used cerebral ischemia/reperfusion as a model to investigate the interaction between apoptosis and necroptosis. We show that the activation of RIPK1 sequentially promotes necroptosis followed by apoptosis…
20h
Sexual misconduct legal battle raises questions about microbe researcher's work
Defamation lawsuit brings allegations and past legal problems to light
3h
Sexually dimorphic role of oxytocin in medaka mate choice [Ecology]
Oxytocin is a central neuromodulator required for facilitating mate preferences for familiar individuals in a monogamous rodent (prairie vole), irrespective of sex. While the role of oxytocin in mate choice is only understood in a few monogamous species, its function in nonmonogamous species, comprising the vast majority of vertebrate species,…
20h
Share your views on gene editing
We would like to find out what you think about gene editing. What are the benefits – and the downsides for society? Gene editing is a group of technologies that gives scientists the ability to change an organism's DNA. These technologies have the power to change life as we know it, but what do people really think about how we should use them? Continue reading…
4h
Shocker: The Western World's Diet Is Making Everyone Scientifically Brain-Dumber
A "Western diet" (or the "Western pattern diet") is exactly what you think: Fatty, sugary, salty, and lousy with red meat and processed products — in stark contrast to diets comprised mostly of whole grains, or plants, or legumes, or natural fats. As you also might guess, the Western diet is regularly linked to historical upticks in obesity, diabetes, high blood pressure, cardiovascular disease,
2h
Should we edit our DNA? An imagined future of gene editing – video
There are decisions being made right now that could have an effect on global populations for generations to come. As part of this project, we commissioned an artist to investigate some of the themes raised in the podcasts. This work of fiction imagines a future where gene editing has become mainstream and discusses the moral, ethical and political divides that this might create Continue reading..
8h
Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2024-3 Single-cell RNA sequencing and spatial transcriptomics reveal that the somitogenesis clock is active in mouse gastruloids, which can be induced to generate somites with the correct rostral–caudal patterning.
5h
Single-Sex Wedding Parties Don't Make Sense Anymore
Every weekday at 7:40 a.m., the hosts of a program called The Anna & Raven Show give early-rising commuters in Connecticut and New York the opportunity to weigh in on a local couple's dispute in a recurring segment called "Couple's Court." "Couple's Court" is precisely the kind of thing that's irresistible to the hopelessly nosy—and a few weeks ago, on a Monday morning, an engaged couple named Ad
8h
Size-adjustable prosthetic heart valve accommodates heart growth in sheep
Taking a step towards a major goal in heart valve prosthetics, scientists have created an adaptable heart valve replacement that can be expanded over time as the heart grows.
1h
Skeptical Science New Research for Week #7, 2020
"You're going to need a longer runway" Gratton et al explore the ongoing effects of upward-creeping temperatures on aviation in Greece in the period since 1955 at a range of airports in that country. For longer runways impacts are measurable but with little impact on operations. For airports with shorter runways, there's quite a difference, measurable over the service life of a single model of ai
15h
Slithering snakes on a 2D plane
Snakes live in diverse environments ranging from unbearably hot deserts to lush tropical forests, where they slither up trees, rocks and shrubbery every day. By studying how these serpents move, Johns Hopkins engineers have created a snake robot that can nimbly and stably climb large steps.
20h
Smart contact lens sensor developed for point-of-care eye health monitoring
A research group led by Prof. DU Xuemin from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has developed a "smart" contact lens that can show real-time changes in moisture and pressure by altering colors.
6h
Snakes in the lab, but all is well
Engineers develop a robot that can climb like a kingsnake.
2h
Spanish modified Story Memory Technique efficacious for Mexicans with multiple sclerosis
Researchers adapted the English language Kessler Foundation modified Story Memory Technique into Spanish. 'This is an example of how cultural adaptation can extend evidence-based interventions to non-English speaking populations,' said Dr. Krch. 'The positive outcomes of this pilot study of urban-based Mexicans have important implications. While further testing is needed, we anticipate that this a
3h
Spatial mapping of tissue properties in vivo reveals a 3D stiffness gradient in the mouse limb bud [Engineering]
Numerous hypotheses invoke tissue stiffness as a key parameter that regulates morphogenesis and disease progression. However, current methods are insufficient to test hypotheses that concern physical properties deep in living tissues. Here we introduce, validate, and apply a magnetic device that generates a uniform magnetic field gradient within a space…
20h
sphingotec's biomarker penKid® shows best representation of true glomerular filtration rate and has utility in patients with severe burns two studies show
In-depth method comparison by Dutch group shows that sphingotec's proprietary kidney function biomarker penKid® is currently the most accurate surrogate marker for true glomerular filtration rate in patients with renal impairment
12h
Spontaneous cures, seeing the stars, and secrets of invisible aircraft: Books in brief
Nature, Published online: 19 February 2020; doi:10.1038/d41586-020-00445-2 Andrew Robinson reviews five of the week's best science picks.
11h
Stitching the synapse: Cross-linking mass spectrometry into resolving synaptic protein interactions
Synaptic transmission is the predominant form of communication in the brain. It requires functionally specialized molecular machineries constituted by thousands of interacting synaptic proteins. Here, we made use of recent advances in cross-linking mass spectrometry (XL-MS) in combination with biochemical and computational approaches to reveal the architecture and assembly of synaptic protein com
1h
Store huller i 'sikker' mail: Simpel fejl har medført 251 anmeldelser til Datatilsynet
PLUS. Uvedkommende har kunnet læse alt på en dansk mailløsning, der bruges af kommuner, forsikringsselskaber, advokater og mange andre til at sende fortrolige oplysninger.
11h
Stort ingrepp i organismernas släktträd
Vetenskapen är aldrig färdig. Länge har man ansett att den gren på evolutionsträdet som ledde till växter grenades av först från den som ledde till både svampar och djur (och oss människor). Nu skriver forskare i en ny artikel i den amerikanska vetenskapsakademins tidskrift, att man efter jämförelse av hela genuppsättningar och proteininnehåll kommit fram till att svamparna grenades av först från
11h
15h
Stressed corals set up progeny for a better life
First evidence that animal DNA methylation patterns can be passed to the next generation.
5h
Structural basis of energy transfer in Porphyridium purpureum phycobilisome
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2020-7 The cryo-electron microscopy structure of a phycobilisome from the red alga Porphyridium purpureum reveals how aromatic interactions between the linker proteins and the chromophores drive a unidirectional transfer of energy.
5h
Structural basis of ligand recognition and self-activation of orphan GPR52
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2019-0 Structures of the orphan G-protein-coupled receptor GPR52 in ligand-free, G-protein-coupled and ligand-bound states reveal that extracellular loop 2 occupies the orthosteric binding pocket and functions as a built-in agonist to activate the receptor.
5h
Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation [Microbiology]
Paramyxoviruses are enveloped, nonsegmented, negative-strand RNA viruses that cause a wide spectrum of human and animal diseases. The viral genome, packaged by the nucleoprotein (N), serves as a template for the polymerase complex, composed of the large protein (L) and the homo-tetrameric phosphoprotein (P). The ∼250-kDa L possesses all enzymatic…
16 min
Study finds disparities in timing and type of treatment in colorectal cancer patients
A new study from George Mason University published in Cancer Epidemiology found racial disparities in how the presence of cancer-related diagnostic and treatment technology is related to the time-to-treatment for whites and blacks with colorectal cancer (CRC) in Georgia. The study evaluated the time-to-treatment and survival rates of patients in relation to cancer-related technologies of the diagn
6h
Surface reservoirs dominate dynamic gas-surface partitioning of many indoor air constituents
Human health is affected by indoor air quality. One distinctive aspect of the indoor environment is its very large surface area that acts as a poorly characterized sink and source of gas-phase chemicals. In this work, air-surface interactions of 19 common indoor air contaminants with diverse properties and sources were monitored in a house using fast-response, on-line mass spectrometric and spect
1h
Sustained IFN-I stimulation impairs MAIT cell responses to bacteria by inducing IL-10 during chronic HIV-1 infection
Mucosal-associated invariant T (MAIT) cells in HIV-1–infected individuals are functionally impaired by poorly understood mechanisms. Single-cell transcriptional and surface protein analyses revealed that peripheral MAIT cells from HIV-1–infected subjects were highly activated with the up-regulation of interferon (IFN)–stimulated genes as compared to healthy individuals. Sustained IFN-α treatment
1h
Sweet beaks: What Galapagos finches and marine bacteria have in common
Ecological niches are a concept well known from higher animals. Apparently, bacteria act accordingly. Researchers from the Max-Planck-Institute for Marine Microbiology in Bremen have found that marine Polaribacter bacteria find their ecological niche by specializing on their favorite sugar. They now present their results in ISME Journal.
5h
Tadpole hatchlings suck bubbles to breathe
High-speed camera catches them in the act.
2h
Team breaks reciprocity in acoustic waves
Engineers have demonstrated the ability to break reciprocity in acoustic waves, which advances an emerging field of spacetime-varying metamaterials. In physics, for example, reciprocity concerns electromagnetic and acoustic waves . The idea is that waves travel the same way backward as they do forward. Which is fine, except that waves encounter obstacles (skyscrapers, wind, people) that cause the
1h
Tel Aviv University researchers discover receptor chain involved in atopic dermatitis
A new Tel Aviv University study identifies the precise receptor chain involved in the development of atopic dermatitis, the most common cause of eczema. The researchers hope to develop an antibody based on this research to create a therapeutic drug.
4h
The 'ancestral diet' doesn't make sense and relies on lazy stereotypes
Eating like your ancestors did 5000 years ago is a fad on the rise. James Wong wonders if following the "ancestral diet" means he should eat pangolins or live a life of abject poverty
2h
The beautiful, hard work of co-parenting | Joel Leon
"Co-parenting" isn't a buzzword — it's a way of showing up for your family openly, consistently and lovingly, says storyteller and father Joel Leon. In this moving talk, he challenges all parents to play an equal, active role in their children's daily lives, even in a world that often places the weight of sacrifice on mothers alone. Leon encourages nuanced conversations about parenting and remind
5h
The Broadband Industry Is Suing Maine Over a Web Privacy Law
Groups claim the state law, scheduled to take effect in July, violates First Amendment protections and the Supremacy Clause of the constitution.
1h
The Delicate and Demanding World of Emma
This might sound like a ludicrous complaint, but moviegoers have been bereft of Jane Austen adaptations of late. Yes, almost all of the celebrated author's works have been committed to film at one point or another; a boom began in the '90s and ran into the early 2000s, yielding such memorable efforts as Ang Lee's Sense and Sensibility , Douglas McGrath's Emma , Patricia Rozema's Mansfield Park ,
9h
The dynamics of stem and crown groups
The fossil record of the origins of major groups such as animals and birds has generated considerable controversy, especially when it conflicts with timings based on molecular clock estimates. Here, we model the diversity of "stem" (basal) and "crown" (modern) members of groups using a "birth-death model," the results of which qualitatively match many large-scale patterns seen in the fossil recor
1h
The evolution of early symbolic behavior in Homo sapiens [Psychological and Cognitive Sciences]
How did human symbolic behavior evolve? Dating up to about 100,000 y ago, the engraved ochre and ostrich eggshell fragments from the South African Blombos Cave and Diepkloof Rock Shelter provide a unique window into presumed early symbolic traditions of Homo sapiens and how they evolved over a period of…
20h
The grain boundary mobility tensor [Engineering]
The grain-boundary (GB) mobility relates the GB velocity to the driving force. While the GB velocity is normally associated with motion of the GB normal to the GB plane, there is often a tangential motion of one grain with respect to the other across a GB; i.e., the GB velocity…
20h
The green chemistry of fullerene
Scientists from the Skoltech Center for Energy Science and Technology (CEST) and the Institute for Problems of Chemical Physics of Russian Academy of Sciences have developed a novel approach for preparing thin semiconductor fullerene films. The method enables fabrication of organic electronics without using toxic organic solvents and costly vacuum technologies, thus reducing the environmental risk
5h
The Killer Robot Takeover is Inevitable
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16h
The Many Meanings of "I Can't"
So much can hide behind those two little words — Read more on ScientificAmerican.com
6h
LATEST
Scientists Announce Fresh Experiments On Antimatter
Researchers have conducted a new test on antimatter — matter's weird opposite. The researchers found that anti-hydrogen atoms behave exactly the same as regular hydrogen. But many questions remain.
now
Baby Born from Egg that Was Matured and Frozen in the Lab
A cancer patient who underwent the new fertility preservation procedure successfully gave birth five years after her immature eggs were collected.
6 min
The New Explosive Theory About What Doomed the Crew of the 'Hunley'
A blast-injury expert takes aim at the mystery of what sank the most famous—and lethal—submarine of the Civil War
5h
The next chapter for African genomics
Nature, Published online: 19 February 2020; doi:10.1038/d41586-020-00454-1 Nigeria is poised to become a hub for genetics research, but a few stubborn challenges block the way.
9h
The ones who got away from Time and Loss
Nature, Published online: 19 February 2020; doi:10.1038/d41586-020-00470-1 A moment to reflect.
7h
The potentially deadly paradox of diabetes management
Diabetes affects nearly 1 in 10 adults in the US, of these millions, more than 90% have Type 2 diabetes. Controlling blood sugar and glycosylated hemoglobin levels — or HbA1c, which is sometimes referred to as A1C — is key to diabetes management and necessary to prevent its immediate and long-term complications. However, new Mayo Clinic research shows that diabetes management may be dangerously
6h
The process of Lewy body formation, rather than simply {alpha}-synuclein fibrillization, is one of the maȷor drivers of neurodegeneration [Neuroscience]
Parkinson's disease (PD) is characterized by the accumulation of misfolded and aggregated α-synuclein (α-syn) into intraneuronal inclusions named Lewy bodies (LBs). Although it is widely believed that α-syn plays a central role in the pathogenesis of PD, the processes that govern α-syn fibrillization and LB formation remain poorly understood. In…
16 min
The role of sex work laws and stigmas in increasing HIV risks among sex workers
Nature Communications, Published online: 18 February 2020; doi:10.1038/s41467-020-14593-6 HIV incidence among sex workers remains high in many settings. Here, the authors utilize individual-level data across ten countries in sub-Saharan Africa and suggest that increasingly punitive and non-protective laws are associated with HIV, and that stigmas and sex work laws may operate jointly in increasin
11h
The Show That Actually Understands Modern Romance
The final scene of Hulu's High Fidelity seems poised to play out a classic rom-com moment: The lonely record-store owner Robin, a.k.a. "Rob" (played by Zoë Kravitz), shows up at the apartment of her love interest, Clyde (Jake Lacy), who's been avoiding her calls since a falling-out a few episodes back. The inevitable seems to be coming: She'll confess her feelings, he'll accept them, and they'll
10h
The size of the immune repertoire of bacteria [Biophysics and Computational Biology]
Some bacteria and archaea possess an immune system, based on the CRISPR-Cas mechanism, that confers adaptive immunity against viruses. In such species, individual prokaryotes maintain cassettes of viral DNA elements called spacers as a memory of past infections. Typically, the cassettes contain several dozen expressed spacers. Given that bacteria can…
20h
The Surprisingly Fraught Question of Who Pays for Birth Control
In 2017, Taylor Kay Phillips was debating two things: whether she wanted to switch from the pill to an IUD, and, if she did, whether she should ask her boyfriend, Felipe Torres, to help pay for it. At the time, Phillips—now a comedy writer in New York City—was unemployed, and her insurance plan wouldn't cover the $1,100 bill. But she was hesitant to ask Torres to pitch in. Phillips didn't know an
6h
The vortex gas scaling regime of baroclinic turbulence [Earth, Atmospheric, and Planetary Sciences]
The mean state of the atmosphere and ocean is set through a balance between external forcing (radiation, winds, heat and freshwater fluxes) and the emergent turbulence, which transfers energy to dissipative structures. The forcing gives rise to jets in the atmosphere and currents in the ocean, which spontaneously develop turbulent…
20h
The Women's Health Pioneer You've Probably Never Heard Of
The 19th-century black "doctress" Rebecca Davis Lee Crumpler should be on everyone's radar — Read more on ScientificAmerican.com
8h
There could be meteors traveling at close to the speed of light when they hit the atmosphere
It's no secret that planet Earth is occasionally greeted by rocks from space that either explode in the atmosphere or impact on the surface. In addition, Earth regularly experiences meteor showers whenever it passes through clouds of debris in the solar system. However, it has also been determined that Earth is regularly bombarded by objects that are small enough to go unnoticed—about 1 mm or so i
5h
These 10 must-have digital subscriptions are on sale today
Check out 10 digital subscription offers available right now. These offers include language training, cloud storage, VPN protection and more. The deals all come with discounts up to 98% off. If you got a nice holiday check from a relative or even a tidy little Christmas bonus from your employer, think twice before you decide what to do with your windfall. Do you spend it on a spur of the moment i
6h
These Tiny, Solar-Powered Wings Flap Faster Than a Butterfly's
Flappy Bot A team of Chinese researchers has created tiny wings that are capable of flapping faster than butterfly wings — and which need only sunlight as a power source. According to the researchers, the design could allow robots to fly without the need for batteries or could even be used to harvest solar energy. The "flexible bio-butterfly wing" is essentially a thin coated polymer sheet with a
2h
This is our 5,000th post — and we have a $5,000 matching pledge if you can help us for the next 5,000
Nine and a half years ago, Adam Marcus and I had an idea: A blog about retractions. Apparently, we needed to convince ourselves that it was a good idea. Otherwise, why would our first post, on Aug. 3, 2010, be titled "Why write a blog about retractions?" That was post #1. And this, dear reader, … Continue reading
10h
This Is What It Looks Like When a Colossal Bird Migration Obscures a Rain Radar
That's no rain cloud…
15h
This is your brain on air pollution | María Neira
Air pollution knows no borders — even in your own body, says public health expert María Neira. In this startling talk, she describes how the microscopic particles and chemicals you breathe affect all your major organs (including your brain) and calls on both the public and those in power to take action to stop the sources of pollution.
21 min
Thousands of uninsured kidney disease patients strain Texas emergency departments
More than 10,000 uninsured patients sought care at Texas emergency departments for lifesaving kidney dialysis in 2017, incurring more than $21.8 million in hospital costs, according to researchers from UTHealth.
4h
'Throat of Fire' Volcano in Ecuador Shows Early Signs of Collapse, Scientists Warn
A catastrophe not witnessed for 3,000 years.
15h
Tilsynet med almen praksis er i gang: Det bliver lægerne målt på
Efter et års pause fører Styrelsen for Patientsikkerhed igen tilsyn med almen praksis. I år fylder dialogen med lægerne mere end tidligere. Det betyder dog ikke, at venlighedskasketten er trukket helt ned over øjnene.
10h
Time-resolved measurement in a memory device
Researchers at ETH have measured the timing of single writing events in a novel magnetic memory device with a resolution of less than 100 picoseconds. Their results are relevant for the next generation of main memories based on magnetism.
14h
Tombaugh's discovery of Pluto revolutionized knowledge of our solar system
Ninety years ago today, Clyde Tombaugh, a young astronomer working at Lowell Observatory in Flagstaff, Arizona, discovered Pluto. In doing so he unknowingly opened the door to the vast "third zone" of the solar system we now know as the Kuiper Belt, containing countless planetesimals and dwarf planets—the third class of planets in our solar system.
5h
Training the mind in resilience
Two new studies from University of Miami researchers found that offering mindfulness training in high-demand settings bolsters attention and resilience.
3h
Transient invaders can induce shifts between alternative stable states of microbial communities
Microbial dispersal often leads to the arrival of outsider organisms into ecosystems. When their arrival gives rise to successful invasions, outsider species establish within the resident community, which can markedly alter the ecosystem. Seemingly less influential, the potential impact of unsuccessful invaders that interact only transiently with the community has remained largely ignored. Here,
1h
Traumatic brain injury risk is higher for hyperactive boys
Boys who are inattentive and hyperactive at age 10 have a higher risk for traumatic brain injuries in adolescence and adulthood, researchers report. Treatments to reduce these behaviors may decrease the risk for traumatic brain injuries (TBIs), according to the new study. "Traumatic brain injuries are the leading cause of death and disability in children and young adults…" "Traumatic brain injuri
3h
Tricky reaction sequence gets a major boost from a flow setup and statistics
Researchers from Osaka University have shown that the enantioselective organocatalyzed Rauhut-Currier and [3+2] annulation sequence in a microflow system can rapidly produce functionalized chiral spirooxindoles (up to 89% yield, 98% ee) within one minute. Although conventional methods for developing a flow synthesis procedure can be costly and labor-intensive, the researchers efficiently optimized
6h
Tumor blood vessel detection by a gripping force feedback system
Avoiding unnecessary bleeding during neuroendoscopic surgeries is crucial. When blood vessel location in a tumor cannot be visually confirmed, unintentional damage to the vessel and subsequent bleeding may occur. We propose a method for tumor blood vessel detection using a surgical robot system equipped with a force sensor in the gripper. Using this method, pulsation of a simulated artery inside a
5h
Tunable and precise miniature lithium heater for point-of-care applications [Engineering]
Point-of-care diagnostic assays often involve multistep reactions, requiring a wide range of precise temperatures. Although precise heating is critical to performing these assays, it is challenging to provide it in an electricity-free format away from established infrastructure. Chemical heaters are electricity-free and use exothermic reactions. However, they are unsuitable for…
20h
Twenty-six cadets in their final year at West Point are conducting bio-printing research that aims to create stem-cell laden bandages for burns in the field, bio-printed menisci and livers, and one day even build bio-engineered blood vessels to make organs viable
submitted by /u/quantumcipher [link] [comments]
6h
Tyrosine phosphorylation of the AMPA receptor subunit GluA2 gates homeostatic synaptic plasticity [Neuroscience]
Hebbian plasticity, comprised of long-term potentiation (LTP) and depression (LTD), allows neurons to encode and respond to specific stimuli; while homeostatic synaptic scaling is a counterbalancing mechanism that enables the maintenance of stable neural circuits. Both types of synaptic plasticity involve the control of postsynaptic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) recep
20h
UArizona Health Sciences researchers uncover potential new therapy for concussion-related headaches
Now a Tucson physical therapist and soccer coach, Kelly Farrell collided skulls with a teammate while heading a ball during her junior year of college. She was diagnosed with a concussion, which proved to be severely debilitating. Researchers at the University of Arizona's College of Medicine – Tucson have teamed with scientists at two other institutions to identify the cause of post-brain injury
6h
UCLA researchers discover new compound that promotes lung health
A molecule identified by UCLA researchers helps maintain a healthy balance of cells in airway and lung tissue. If the compound, so far only studied in isolated human and mouse cells, has the same effect in people, it may lead to new drugs to treat or prevent lung cancer.
5h
UCLA researchers find new method for measuring treatment of rare liver disease in children
UCLA researchers who previously found that intravenous administration of fish oil can treat a rare but potentially deadly form of liver disease in children have now monitored levels of a small molecule at the center of the disorder to track treatment results.
6h
Uganda army fights voracious desert locusts
Under a warm morning sun scores of weary soldiers stare as millions of yellow locusts rise into the northern Ugandan sky, despite hours spent spraying vegetation with chemicals in an attempt to kill them.
8h
UK: Hornsea Two green hydrogen plans tested. The world's largest offshore wind farm may produce green hydrogen that will power an oil and gas refinery in the north-east of England as part of an industrial-scale trial of the technology.
submitted by /u/chopchopped [link] [comments]
6h
Unraveling the physics behind tossing fried rice
A pair of researchers at the Georgia Institute of Technology has unraveled the physics behind the optimal way to toss fried rice while it is cooking. In their paper published in Journal of the Royal Society Interface, Hungtang Ko and David Hu describe filming chefs in Chinese restaurants cooking fried rice and what they learned about the physics involved.
5h
Various variability phenomena observed in the binary star DQ Tau
Hungarian astronomers have observed a pre-main sequence (PMS) binary star known as DQ Tau using a set of space telescopes and ground-based facilities, finding numerous variability phenomena in this system, including energetic stellar flares. The findings are detailed in a paper published February 11 on arXiv.org.
7h
Vascular endothelium-targeted Sirt7 gene therapy rejuvenates blood vessels and extends life span in a Hutchinson-Gilford progeria model
Vascular dysfunction is a typical characteristic of aging, but its contributing roles to systemic aging and the therapeutic potential are lacking experimental evidence. Here, we generated a knock-in mouse model with the causative Hutchinson-Gilford progeria syndrome (HGPS) Lmna G609G mutation, called progerin. The Lmna f/f ;TC mice with progerin expression induced by Tie2-Cre exhibit defective mi
1h
Veggie-loving fish could be the new white meat
A secret to survival amid rising global temperatures could be dwelling in the tidepools of the U.S. West Coast. Findings by University of California, Irvine biologists studying the genome of an unusual fish residing in those waters offer new possibilities for humans to obtain dietary protein as climate change imperils traditional sources. Their paper appears in Proceedings of the Royal Society B.
1h
Ventral prostate and mammary gland phenotype in mice with complete deletion of the ER{beta} gene [Medical Sciences]
Disagreements about the phenotype of estrogen receptor β (ERβ) knockout mouse, created by removing the DNA-binding domain of the ERβ gene or interruption of the gene with a neocassette (Oliver Smithies ERβ knockout mice [ERβOS−/−]), prompted us to create an ERβ knockout mouse by deleting the ERβ gene with the…
16 min
Vi skal blive bedre til at se og plukke de lavthængende frugter, når vi vil forbedre sundhedsvæsenet
To projekter havde samme mål, men tilgangen var forskellig. Martin Sandberg Buch forklarer, hvordan to projekter i Odense endte med, at det ene gav en besparelse på ca. 1.150 kr. pr. henvist patient, mens det andet gav et merforbrug på ca. 41.000 kr. pr. henvist patient.
11h
Victims of NIMBYism, Unite
The headline on the cover of Time magazine read "Sky High Housing." Behind it was a graphic of a young couple and their dog looking upward to the sky as their dream home floated away. The story was about rising home prices locking a generation of buyers out of the market. It was published on September 12, 1977, but might as well have been yesterday. The United States has a housing crisis. By now,
10h
Video explaining the causes and implications of present bias. Transcripts and citations – https://www.gonudgeyourself.com/post/present-bias
submitted by /u/hsnaras [link] [comments]
9h
Video Shows Iran's Humanoid Robot Drill Through Wall, Snap Selfie
Oh Yeah! A team of engineers from the University of Tehran just unveiled a surprisingly sophisticated humanoid robot. Dubbed Surena IV, the robot is the latest iteration in the University of Tehran's Center for Advanced Systems and Technologies' decade-long project to build highly-functional human-like robots, according to IEEE Spectrum . In a new highlight reel , Surena IV is seen, among other t
3h
Vinder: Vi stoler mest på egne kvalitetsdata
Thoraxkirurgisk Afdeling på Rigshospitalet er Danmarks bedste til klapoperation med samtidig bypass. Interview med ledende overlæge Jesper Ravn.
9h
Vision for primate neuroimaging to accelerate scientific and medical breakthroughs
A global community of over 150 scientists studying the primate brain has released a blueprint for developing more complete 'wiring diagrams' of how the brain works that may ultimately improve understanding of many brain disorders.
4h
Walking the wire: Real-time imaging helps reveal active sites of photocatalysts
Nanoscale photocatalysts are small, man-made particles that harvest energy from sunlight to produce liquid fuels and other useful chemicals. But even within the same batch, the particles tend to vary widely in size, shape and surface composition. That makes it hard for researchers to tell what's really doing the work.
7h
Watch a Violinist Play While Surgeons Operate on Her Brain
The brain is a delicate instrument. Any neurosurgery risks permanently altering a patient's cognitive capabilities. Protecting a patient's talents during surgery can be a complex task for surgeons — as evidenced by a white-knuckles video shared recently by The Guardian . In the clip, 53-year-old Dagmar Turner plays sections of compositions by Mahler and Gershwin as surgeons work to remove a tumor
2h
Watch tadpoles breathe by sucking in air bubbles at water's surface
Most tadpoles breathe air but they are too weak to break the elastic "skin" on top of ponds created by water tension – so they suck air bubbles from the surface
20h
We were promised flying cars…
submitted by /u/bildungsromance [link] [comments]
4h
Weed-derived compounds in Serbian groundwater could contribute to endemic kidney disease
People living in Balkan farming villages along the Danube River have long suffered from a unique type of kidney disease known as Balkan endemic nephropathy. Recently, scientists linked the disorder to compounds from a local weed that could be taken up into food crops from the soil. Now, researchers reporting in ACS' journal Environmental Science & Technology have discovered that contaminated groun
4h
Whale cams track swimming efficiency of ocean giants
The relatively squat and gangly humpback whale moves more efficiently through the water than its sleeker, larger cousin, the blue whale, according to new research that used devices attached to the animals to collect information about these large creatures.
5h
What AI still can't do: Artificial intelligence won't be very smart if computers don't grasp cause and effect. That's something even humans have trouble with.
submitted by /u/filosoful [link] [comments]
2h
What happen to the Russian billionaire who said he was gonna be immortal ?
The one who made the avatar 2045 thing. submitted by /u/sufyanlol [link] [comments]
14h
What If 'Planetary Alignment' Really Could Make Brooms Balance?
Celestial bodies aren't the reason broomsticks can stand up on end. If they were, it would unleash gravitational chaos.
7h
What if we could teach photons to behave like electrons?
The researchers tricked photons – which are intrinsically non-magnetic – into behaving like charged electrons. They accomplished this by sending the photons through carefully designed mazes in a way that caused the light particles to behave as if they were being acted upon by what the scientists called a "synthetic" or "artificial" magnetic field.
1h
What is classical liberalism? | Classical Liberalism
The moral and political philosophy known as classical liberalism is built around a number of core concepts, including, perhaps most importantly, human dignity and individual liberty. Emily Chamlee-Wright, president of the Institute for Humane Studies, introduces these two principles as forces that shape the liberal notion of justice. This applies to both individuals' treatment of others, as well
10h
Whisker-printing to identify individual lions
New technique better maps their numbers and density.
2h
Why East Asians but not South Asians are underrepresented in leadership positions in the United States [Psychological and Cognitive Sciences]
Well-educated and prosperous, Asians are called the "model minority" in the United States. However, they appear disproportionately underrepresented in leadership positions, a problem known as the "bamboo ceiling." It remains unclear why this problem exists and whether it applies to all Asians or only particular Asian subgroups. To investigate the…
20h
Why the Fastest Growing Population in America Is The Least Likely to Fill Out the Census
submitted by /u/izumi3682 [link] [comments]
8h
Will the latest UK Research Excellence Framework turn out to be the last?
Nature, Published online: 19 February 2020; doi:10.1038/d41586-020-00451-4 The REF is unpopular but researchers should beware unintended consequences if it is abolished.
10h
Yes, the Australian bush is recovering from bushfires—but it may never be the same
As bushfires in New South Wales are finally contained, attention is turning to nature's recovery. Green shoots are sprouting and animals are returning. But we must accept that in some cases, the bush may never return to its former state.
6h
You Can Now Get A Degree In Marijuana At The Colorado State University
submitted by /u/NickyK01 [link] [comments]
10h
Your home's water quality could vary by the room—and the season
Is the water in your home actually safe, given that water utility companies in the U.S. aren't required by law to monitor the water that specifically enters a building at its service line?
1h
Zero's new electric motorcycle directs the wind around the rider for a more comfortable cruise
Zero SR/S Electric
The new electric SR/S street bike. (Zero Motorcycles/) We're well into the age of electric motorcycles . Harley-Davidson makes the electron-fueled LiveWire , and Damon is eyeing 2021 for delivery of its HyperSport . And today, Zero Motorcycles, which has actually been selling electric two-wheelers since 2007, literally took the cover off its latest bike, the SR/S. The SR/S is a street bike with a
15 min
Zinc isotopes in Late Pleistocene fossil teeth from a Southeast Asian cave setting preserve paleodietary information [Biochemistry]
Stable carbon and nitrogen isotope ratios of collagen from bone and dentin have frequently been used for dietary reconstruction, but this method is limited by protein preservation. Isotopes of the trace element zinc (Zn) in bioapatite constitute a promising proxy to infer dietary information from extant and extinct vertebrates. The…
20h
γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis
Nature, Published online: 19 February 2020; doi:10.1038/s41586-020-2028-z Vγ6+ Vδ1+ γδ T cells control tolerance to cold by activating adipocyte IL-17RC and promoting sympathetic innervation of thermogenic adipose tissue in mice.
5h
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