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nyheder2020januar01

Prevention of tuberculosis in macaques after intravenous BCG immunization

Nature, Published online: 01 January 2020; doi:10.1038/s41586-019-1817-8 The delivery route and dose of the BCG vaccine profoundly alters the protective outcome after Mycobacterium tuberculosis challenge in non-human primates.

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Field-resolved infrared spectroscopy of biological systems

Nature, Published online: 01 January 2020; doi:10.1038/s41586-019-1850-7 A vibrational spectroscopy technique that measures the electric field emitted from organic molecules following infrared illumination allows their molecular fingerprints to be separated from the excitation background, even in complex biological samples.

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Assessing progress towards sustainable development over space and time

Nature, Published online: 01 January 2020; doi:10.1038/s41586-019-1846-3 Systematic methods for evaluating progress towards the 17 United Nations Sustainable Development Goals are developed and tested using 119 indicators at China's national and subnational levels during 2000–2015, showing improvement overall.

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Atomic imaging of the edge structure and growth of a two-dimensional hexagonal ice

Nature, Published online: 01 January 2020; doi:10.1038/s41586-019-1853-4 Real-space imaging of the edge structures and growth of a two-dimensional ice on a gold substrate is achieved using noncontact atomic-force microscopy with a carbon monoxide tip.

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Delivering TB vaccine intravenously dramatically improves potency, study shows

Worldwide, more people die from tuberculosis than any other infectious disease, even though the vast majority were vaccinated. The vaccine just isn't that reliable. But a new Nature study finds that simply changing the way the vaccine is administered could dramatically boost its protective power.

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Changed route of immunization dramatically improves efficacy of TB vaccine

Tuberculosis (TB), an ancient disease, is the leading infectious cause of death globally, yet the world's only licensed TB vaccine, Bacille Calmette-Guerin (BCG), was developed a century ago. Given to infants via a needle placed just under the skin, BCG protects babies from a form of the disease called disseminated TB but is far less effective at preventing pulmonary TB, the major cause of illness

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New study estimates the global extent of river ice loss as Earth warms

A new study from researchers in the University of North Carolina at Chapel Hill Department of Geological Sciences found that annual river ice cover will decline by about six days for every one degree Celsius increase in global temperatures. This decline will have economic and environmental consequences.

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Spectroscopy: A fine sense for molecules

Scientists at the Laboratory for Attosecond Physics have developed a unique laser technology for the analysis of the molecular composition of biological samples. It is capable of detecting minimal variations in the chemical make up of organic systems.

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All global sustainability is local

Groundbreaking ways to quantify progress towards sustainable development goals find sustainability, like politics, is local.

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New Injection Method Makes an Old TB Vaccine Far More Powerful

Giving the vaccine intravenously to monkeys provided 90% protection against tuberculosis. More testing is needed before humans can be inoculated that way.

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A.I. Is Learning to Read Mammograms

Computers that are trained to recognize patterns and interpret images may outperform humans at finding cancer on X-rays.

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Google AI system beats doctors in breast cancer tests

Algorithm reduces both false positives and false negatives

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AI system outperforms experts in spotting breast cancer

Program developed by Google Health tested on mammograms of UK and US women An artificial intelligence program has been developed that is better at spotting breast cancer in mammograms than expert radiologists. The AI outperformed the specialists by detecting cancers that the radiologists missed in the images, while ignoring features they falsely flagged as possible tumours. Continue reading…

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One Decade, a Lot of Writing

Ten years, measured in words on astrobiology, exoplanets and the cosmos in general — Read more on ScientificAmerican.com

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The 10 best canoe trips in the U.S. and Canada

A packed canoe on the shore in Bowron Lake Provincial Park, of Canada. (Mauritius/) This story originally featured on Field & Stream . Everyone should spend a week paddling in a canoe—if not every year, at least once in their life. There's no better way to get to know someone than being stuck in the same boat for days on end, and it's been the boat of choice for hunters and anglers for centuries.

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Flying Lanterns Probably Caused Zoo Fire in Germany, Police Say

The blaze burned down a primate enclosure, killing at least 30 animals. Three women told the police that they were sorry for using flying lanterns on New Year's Eve.

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A New Way to Establish Cause and Effect in Epidemiology?

A technique called Mendelian randomization is overturning the conclusions of observational studies in public health. But researchers question whether the method can overcome its fundamental limitations.

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7 (more) board games to help kids think big

The number of board games being released each year is unprecedented. Among the deluge of new and interesting titles, many can help develop life-critical skills, such as creativity, problem solving, and lateral thinking. We look at seven more board games that help teach children to think big. We are living in a board game renaissance. Where once families had a paltry selection of dice rollers to c

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The Simple Truth about Physics

Theoretical models can be complex—but the most successful ones are usually not — Read more on ScientificAmerican.com

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Navy scientist known for "UFO-like tech" patents fusion reactor

submitted by /u/eyefish4fun [link] [comments]

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The Simple Truth about Physics

Theoretical models can be complex—but the most successful ones are usually not — Read more on ScientificAmerican.com

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Mobile robotter er noget, man leaser

PLUS. Robotproducenten MiR vil udvikle nye forretningsmodeller inden for service og vedligehold. Det skal en forretningsudviklingschef hjælpe med.

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The Embassy Attack Revealed Trump's Weakness

Over the past 18 months, Donald Trump has picked a fight with Iran that he won't end and can't win. That fight has had horrifying consequences for the Iranian people, led Tehran to restart its nuclear program, and now left parts of the American embassy compound in Baghdad in flames. In the days and weeks to come, Trump's policy will likely lead either to war or to additional American humiliation,

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Podcast: Our reporters' top picks of 2019

Nature, Published online: 01 January 2020; doi:10.1038/d41586-019-03868-8 The podcast team share some of their highlights from the past 12 months.

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Here's What the World Will Look Like in 2030 … Right?

These six visions from humans today span space colonies, a genetic panopticon, and straight-up apocalypse.

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Unforced variations: Jan 2020

The new open thread on climate science for a new year, and a new decade – perhaps the Soaring Twenties ? What precisely will be soaring is yet to be decided though. Two things will almost go up – CO 2 emissions and temperatures: As 2019 wraps up, what can we look forward to in 2020? More of the same, plus a little bit more… pic.twitter.com/nmMP6riIjZ — Gavin Schmidt (@ClimateOfGavin) December 22,

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America Loves Its Unregulated Wellness Chemicals

The middle-aged woman in front of me in the Atlanta airport's check-in line surely meant well. "You should try some CBD for your dog if she gets nervous," she said, motioning to my chihuahua, who sat atop my suitcase, peering uneasily through the mesh panels of her travel carrier. "They say it's great for that." She didn't say who "they" were, but at this point, it could be anyone: her teenage ki

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Chandrayaan-3: India plans third Moon mission

Plans for a new mission come months after the Chandrayaan-2 failed to land on the Moon.

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Palau is first country to ban 'reef toxic' sun cream

The move is designed to protect marine life around the Pacific island state.

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Scientific American's Colorful Covers Reveal 175 Years of Change

The magazine's hues provide a record of publishing technology and trends — Read more on ScientificAmerican.com

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The Amazon Has Lost More Than Ten Million Football Fields of Forest in a Decade

The Royal Statistical Society's stat of the decade is 24,000 square miles of deforestation in the Amazon rainforest

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What's in Your Water?

Download this infographic to learn about the potential contaminants in your lab water, their effects on the accuracy of chromatography-based separation techniques, and how to remove them!

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The game

Nature, Published online: 01 January 2020; doi:10.1038/d41586-019-03903-8 Playing by the rules.

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Predictions for 2020 that weren't exactly right…

submitted by /u/craigiest [link] [comments]

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What U.S. Intelligence Thought 2020 Would Look Like

submitted by /u/ngt_ [link] [comments]

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Beat the clock: the surprising psychology behind being perpetually late

There are as many reasons for unpunctuality as there are habitually tardy people – and the underlying reasons can be complex Sometimes, one of my psychotherapy clients will be late. "The tube got stuck; I do apologise." If it happens once, I don't treat it as significant. But some clients are perpetually late – perhaps just five or 10 minutes, but always – and out of breath when they get to the d

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Brugsanvisningen er på vej i papirkurven

PLUS. Ud med brugsanvisninger på papir og ind med regulering af kunstig intelligens og bedre it-sikkerhed. Sådan ser skitserne til et nyt maskindirektiv ud.

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Why it's tough to sleep in after a night of drinking

There's a scientific reason why you're wide awake only a few hours after finally ending the night. (DepositPhotos/) It's New Years Day. You've just woken up to a barely lit sky, perhaps only a few hours after finally making it to bed covered in glitter and full of champagne. But why are you so darn awake? Part of the problem is that alcohol lowers the quality of your sleep . Several studies have

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How to actually detox

Hint: soothing cucumbers aren't involved (Sarah Gualtieri/Unsplash/) The turn of the decade is mere hours away, but it can be hard to imagine your 2020 self when you're in a ham and egg-nog-induced lethargy. After weeks of inundating our bodies with treats and drinks, nothing is more enticing that the hope of a quick fix, the promise that you'll be back to your best with a little activated charco

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One Way the New Little Women Film Is Radical

This article contains spoilers about the film Little Women. At a pivotal moment in Greta Gerwig's outstanding new screen adaptation of Louisa May Alcott's Little Women , the heroine, Jo March, exclaims to Marmee, "Women have minds and they have souls as well as just hearts. They've got ambition and they've got talent as well as just beauty. I am so sick of people saying that love is just all a wo

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Cities Race to Slow Climate Change—and Improve Life for All

Mayors across the world say we all need to consider how urban planning and climate intersect with well-being.

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#1: A mind-blowing explanation of the speed of light | Top 10 2019

Taking the #1 spot on Big Think's 2019 top 10 countdown, NASA's Michelle Thaller reminds us the only things that travel at the speed of light are photons. Nothing with any mass at all can travel at the speed of light because as it gets closer and closer to the speed of light, its mass increases. And if it were actually traveling at the speed of light, it would have an infinite mass. Light does no

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Everything You Need to Know About the CCPA

The California Consumer Privacy Act, which goes into effect today, gives state residents some new rights over their data.

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In Iraq, the U.S. Gets Hit Where It Hurts

When Iranian student revolutionaries seized the U.S. embassy in Tehran in 1979 and took dozens of American diplomats hostage, it destroyed U.S.-Iranian relations and ruined Jimmy Carter politically. When Islamist militants attacked the U.S. consulate in Benghazi in 2012, killing several Americans including the U.S. ambassador, it became the rallying cry for Republicans (including Donald Trump and

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York to ban cars from city centre

The measure would ban all "non-essential" private car journeys in the city centre by 2023.

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A Bigger Foreign-Policy Mess Than Anyone Predicted

Every four years, after the U.S. presidential election, the National Intelligence Council publishes a report looking ahead to the next two decades in global affairs. We do not have a report to mark the beginning of the 2010s, but the council's 2012 report, " Alternative Worlds ," described two scenarios—the best plausible case and the worst plausible case. In the best-case scenario, "China and th

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Why The Witcher Is Better Than Game of Thrones

The best verdict on Game of Thrones came from one of its guest stars, Ian McShane. With the nonchalance of an actor who spent the '80s making rent by playing a semimystical antiques dealer in a British teatime drama, McShane declared that everyone needed to calm down about George R. R. Martin's epic saga. It was, after all, "only tits and dragons." The reaction from the HBO program's more hard-co

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The 2020 Election Will Break History

The 2020 election will be unprecedented, no matter what. Either President Donald Trump's victory will shatter expectations and academic theories, or his defeat will. If Trump wins in 2020, he will be the first and only impeached president to win reelection. Barring a major change in national polls, he will also be the first president to be elected twice without once winning the popular vote. And

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VIDEO Av av av! Se, hvad der sker i kroppen, når du har tømmermænd

Din krop kommer på overarbejde, når du har tømmermænd.

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Podcast special: Deepfake-videoer kan få hvem som helst til at sige hvad som helst

PLUS. Om kort tid bliver det umuligt at skelne deepfake-videoer genereret med kunstig intelligens fra den ægte vare. Det udfordrer vores kritiske sans, når nogen vil påvirke opinionen, men rummer også en fare for, at vi ikke længere stoler på fakta.

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Medicare For All: A Scientist's Take

Rachel Madley, a Columbia University PhD student, discusses her views on access to healthcare.

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A Strange Black Hole Is Shooting Out Wobbly Jets Because It's Dragging Spacetime

"One of the most extraordinary black hole systems I've ever come across."

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U.S. research teams aim for long-duration storage at $0.05/kWh

submitted by /u/thinkB4WeSpeak [link] [comments]

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Psychology's Bias Toward Rich Western Societies Limits Findings

In recent years, researchers have repeatedly shown that when it comes to personality, environment can play at least as big a role as genetics. But most psychological studies are still done in rich, Western countries — a bias that could be hindering our ability to understand the drivers behind behavior.

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The Tech That Will Invade Our Lives in 2020

From smart homes to ultrafast wireless speeds, here's what to watch.

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New Cruise Ships to Set Sail for Antarctica

Interested in the southernmost continent? Here's a roundup of some of the new ships and itineraries planned for the bucket-list destination.

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The Power of Bad and How to Overcome It review – professional Pollyannas

We are living in a golden age and can defeat negativity, argue John Tierney and Roy F Baumeister in this complacent, reactionary book Without wishing to sound too Prince Andrew about this, there are hotels in New York where I won't stay. One is called the Casablanca, and is extolled in this book as a fine example of how to stick it to the "power of bad". By "bad", the authors don't mean moral or

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Graphene: pencil it in

Innovation: technological revolutions can take decades to get going

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Nine dead after Indonesian capital hit by New Year flooding (Update)

Nine people died after Indonesia's capital was hit by its deadliest flooding in years, authorities said Wednesday, as torrential rains on New Year's Eve left vast swathes of the megalopolis submerged.

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Australia scrambles to reach thousands stranded by bushfires

A major operation to reach thousands of people stranded in fire-ravaged seaside towns was under way in Australia on Wednesday after deadly bushfires ripped through popular tourist spots and rural areas leaving at least eight people dead.

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Palau bans 'reef-toxic' sunscreen

Palau's pioneering ban on "reef-toxic" sunscreens took effect Wednesday as the tiny Pacific island nation introduced strict environmental measures that also include one of the world's largest marine sanctuaries.

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Synthetic spider silk: positive spin

Innovation: bioengineering the stuff makes spidey sense

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Palau bans 'reef-toxic' sunscreen

Palau's pioneering ban on "reef-toxic" sunscreens took effect Wednesday as the tiny Pacific island nation introduced strict environmental measures that also include one of the world's largest marine sanctuaries.

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International Space Station astronauts play with fire for research

Tests to study behaviour of flames in zero gravity suggest fires could be more dangerous on moon than Earth Playing with fire can be dangerous and never more so than when confined in a space capsule floating 250 miles above the Earth. But in the past week astronauts onboard the International Space Station have intentionally lit a series of blazes in research designed to study the behaviour of fla

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Deepfakes breder sig: Den AI-skabte uvirkelighed eroderer vores tillid til fakta

PLUS. I de seneste ni måneder er antallet af florerende deepfake-videoer fordoblet, mens kvaliteten er steget med en fart, der kommer bag på selv eksperterne. Vi skal ruste os til en verden, hvor deep learning på rekordfart producerer falske videoer, kunstige stemmer og troværdige tekster.

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Inside the risky venture of Spaceport America

submitted by /u/samtart [link] [comments]

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What do you think New Years Eve 2119 Will Be Like?

Just curious what do you think human beings will be up to on New Years in the year 2119? Will we still be around? Half machine/half robot? In a vr simulation? Bombed back to the stone age? submitted by /u/DreaminDemon177 [link] [comments]

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Skeptical Science New Research for Week #52, 2019

The other side of the coin Last week's New Research mentioned a New York Times article describing how academic researchers plow straight through holidays with work. On the publishing side: not so much. Argue about priorities but clearly there's a difference in attitudes between the input hopper and the output conveyor. This week's posting presents a starved appearance reflective of a slowdown in

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The joy audit: how to have more fun in 2020

This is the year to start taking happiness seriously. But how – and where do you find the time? Here are the tips and advice you need for a pleasure-filled year The last time I felt joy was at an event that would be many people's vision of hell: a drunken Taylor Swift club-night singalong in the early hours of the morning a few weekends ago. I certainly experience joy, either as peaks of euphoria

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Pro-lifers exploiting civil rights struggles in bid to ban abortions, says new research

New research launches as state legislatures begin reconvening where bans are likely to be introduced.Anti-abortionists 'appropriating' laws that protect same-sex couples and Black citizens.

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Don't know if this is real or not but it seems legit

submitted by /u/Lockkkk [link] [comments]

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Rocket Launches, Trips to Mars and More 2020 Space and Astronomy Events

A year full of highs and lows in space just ended, and the 12 months to come will be full of new highlights in orbit and beyond.

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Meteor Showers in 2020 That Will Light Up Night Skies

All year long, Earth passes through streams of cosmic debris. Here's a list of major meteor showers and how to spot one.

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Computational Psychiatry, Self-Care, and The Mind-Body Problem

Schematic example of how the "mind" (cerebral cortex) is connected to the "body" (adrenal gland) – modified from Fig. 1 ( Dum et al., 2016 ): "Modern medicine has generally viewed the concept of ' psychosomatic ' disease with suspicion. This view arose partly because no neural networks were known for the mind, conceptually associated with the cerebral cortex, to influence autonomic and endocrine

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Drink more recycled wastewater

Nature, Published online: 31 December 2019; doi:10.1038/d41586-019-03913-6 There is no room for squeamishness in the face of the world's growing water shortage — three steps could vastly improve the image of reused water for drinking.

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The super-cool materials that send heat to space

Nature, Published online: 31 December 2019; doi:10.1038/d41586-019-03911-8 Paints, plastics and even wood can be engineered to stay cool in direct sunlight — but their role in displacing power-hungry air conditioners remains unclear.

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U.S. Chief Justice warns of social media's danger to democracy

submitted by /u/izumi3682 [link] [comments]

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The Spider Scientist Who Hates Spiders, And Other Strange Tales

Why some scientists love the seemingly unloveable.

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Shape-controlled single-crystal growth of InP at low temperatures down to 220 {degrees}C [Engineering]

III–V compound semiconductors are widely used for electronic and optoelectronic applications. However, interfacing III–Vs with other materials has been fundamentally limited by the high growth temperatures and lattice-match requirements of traditional deposition processes. Recently, we developed the templated liquid-phase (TLP) crystal growth method for enabling direct growth of shape-controlled s

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Microglial IRF5-IRF4 regulatory axis regulates neuroinflammation after cerebral ischemia and impacts stroke outcomes [Neuroscience]

Microglial activation plays a central role in poststroke inflammation and causes secondary neuronal damage; however, it also contributes in debris clearance and chronic recovery. Microglial pro- and antiinflammatory responses (or so-called M1-M2 phenotypes) coexist and antagonize each other throughout the disease progress. As a result of this balance, poststroke immune…

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Reward does not facilitate visual perceptual learning until sleep occurs [Psychological and Cognitive Sciences]

A growing body of evidence indicates that visual perceptual learning (VPL) is enhanced by reward provided during training. Another line of studies has shown that sleep following training also plays a role in facilitating VPL, an effect known as the offline performance gain of VPL. However, whether the effects of…

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Switching sides—Reengineered primary charge separation in the bacterial photosynthetic reaction center [Biophysics and Computational Biology]

We report 90% yield of electron transfer (ET) from the singlet excited state P* of the primary electron-donor P (a bacteriochlorophyll dimer) to the B-side bacteriopheophytin (HB) in the bacterial photosynthetic reaction center (RC). Starting from a platform Rhodobacter sphaeroides RC bearing several amino acid changes, an Arg in place…

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Proteome-wide observation of the phenomenon of life on the edge of solubility [Biophysics and Computational Biology]

To function effectively proteins must avoid aberrant aggregation, and hence they are expected to be expressed at concentrations safely below their solubility limits. By analyzing proteome-wide mass spectrometry data of Caenorhabditis elegans, however, we show that the levels of about three-quarters of the nearly 4,000 proteins analyzed in adult animals…

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Crystal structure of human LDB1 in complex with SSBP2 [Biophysics and Computational Biology]

The Lim domain binding proteins (LDB1 and LDB2 in human and Chip in Drosophila) play critical roles in cell fate decisions through partnership with multiple Lim-homeobox and Lim-only proteins in diverse developmental systems including cardiogenesis, neurogenesis, and hematopoiesis. In mammalian erythroid cells, LDB1 dimerization supports long-range connections between enhancers and…

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Combinatorial interactions of the LEC1 transcription factor specify diverse developmental programs during soybean seed development [Plant Biology]

The LEAFY COTYLEDON1 (LEC1) transcription factor is a central regulator of seed development, because it controls diverse biological programs during seed development, such as embryo morphogenesis, photosynthesis, and seed maturation. To understand how LEC1 regulates different gene sets during development, we explored the possibility that LEC1 acts in combination with…

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A general-purpose protein design framework based on mining sequence-structure relationships in known protein structures [Biophysics and Computational Biology]

Current state-of-the-art approaches to computational protein design (CPD) aim to capture the determinants of structure from physical principles. While this has led to many successful designs, it does have strong limitations associated with inaccuracies in physical modeling, such that a reliable general solution to CPD has yet to be found….

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F.D.A. Plans to Ban Most E-Cigarette Flavors but Menthol

The tobacco and vaping industries and conservative allies intensively lobbied against a ban on popular flavored e-cigarettes.

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Could relatives of measles virus jump from animals to us?

A group of viruses, of which measles is one, are adept at jumping to species barrier.

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Two radically new drugs bring hope for people with depression. But psychiatrists are skeptical.

"It's clear there are multiple kinds of depression out there with different causes." (Tengy Art/Unsplash/) Depression is complicated, and so is treating it. Of the millions of Americans diagnosed with depressive disorders, up to 30 percent struggle to find relief with existing medications. Even so, the U.S. Food and Drug Administration (FDA) hasn't approved a truly new antidepressant in the past

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Asian countries watch as Singapore expands 'war on diabetes'

Absolute advertising ban proposed on high-sugar drinks as part of fight against disease

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Science Panel Staffed With Trump Appointees Says E.P.A. Rollbacks Lack Scientific Rigor

The Trump administration staffed an E.P.A. advisory panel with its choice of scientists, but they concluded that three significant regulatory rollbacks broke with established science.

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Visualising the amount of microplastic we eat

submitted by /u/yieldingTemporarily [link] [comments]

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Stolen Research: Chinese Scientist Is Accused of Smuggling Lab Samples

Zaosong Zheng, a promising cancer researcher, confessed that he had planned to take the stolen samples to Sun Yat-sen Memorial Hospital, and publish the results under his own name.

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The Antarctic Wonderland | The Impossible Row | Episode 13

The rowers spot land and as they approach the continent, an antarctic wonderland is revealed. Touching ground is both dramatic and emotional as the rowers celebrate their world record achievement. Stream More Episodes of The Impossible Row: https://go.discovery.com/tv-shows/the-impossible-row/ About The Impossible Row: The Drake Passage is the most dangerous 600 miles of open ocean on Earth. Worl

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Story of the Year: Humanity's First Look at a Black Hole

#1 in our top science stories of 2019.

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NASA to Announce New Discoveries at Annual Astronomy Meeting

submitted by /u/jamesgalb [link] [comments]

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When will technology allow for humans to choose how pretty or ugly they are?

Can anyone give any examples? Makeup is a lie.. I'm talking about rejuvenation, cure for baldness, medication for changing eye colour for a few months to nanotech literally allowing your body to reshape… Where are we going in the next 10 years and who's taking us their? submitted by /u/p3opl3 [link] [comments]

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Leaked GPU Specs Suggest Xbox Series X Substantially More Powerful Than PS5

A new set of rumors have leaked regarding the next-generation Xbox and PS5 and the GPUs both consoles will bring to market. We've known the broad specs of both platforms for a bit — both use AMD GPUs and CPUs, with the GPU based on AMD's most recent RDNA architecture, while the CPU is derived from the same 7nm Ryzen CPU cores that launched earlier this summer. What we've lacked is specific detail

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Meet Steve, the winter sky phenomenon

Steve has been around for eons, but has been mis-identified as aurora until now Hands up if you've ever seen Steve. No, not the chap living down the road, but Steve the winter sky phenomenon . First spotted by auroral photographers in 2016, "Steve" is a purple band of light, sometimes accompanied by green lines, nicknamed "picket-fences". Although Steve shares similarities with auroras – the glow

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The Problem With a Host Country Failing to Protect Its Embassies

When hundreds of Iraqi protesters stormed the U.S. embassy in Baghdad today, they were met with little resistance. Though American guards attempted to keep the demonstrators at bay with tear gas and stun grenades , Iraqi authorities ultimately failed to prevent them from breaking through the embassy gates, leaving American personnel trapped inside . That demonstrators were able to breach the larg

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Our favorite science and tech stories of 2019

After writing and editing countless stories this year, we decided to pick out our favorites. (Deposit Photos/) A lot of momentous events went down in 2019, from our first image of a black hole to Greta Thunberg's proliferation of climate activism around the globe. In other words, we've had a busy year at Popular Science covering news that shocked, delighted, and amused us. Here are our favorite s

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Munc13-1 MUN domain and Munc18-1 cooperatively chaperone SNARE assembly through a tetrameric complex [Biophysics and Computational Biology]

Munc13-1 is a large multifunctional protein essential for synaptic vesicle fusion and neurotransmitter release. Its dysfunction has been linked to many neurological disorders. Evidence suggests that the MUN domain of Munc13-1 collaborates with Munc18-1 to initiate SNARE assembly, thereby priming vesicles for fast calcium-triggered vesicle fusion. The underlying molecular mechanism,…

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Variable functional connectivity architecture of the preterm human brain: Impact of developmental cortical expansion and maturation [Neuroscience]

Functional connectivity (FC) is known to be individually unique and to reflect cognitive variability. Although FC can serve as a valuable correlate and potential predictor of (patho-) physiological nervous function in high-risk constellations, such as preterm birth, templates for individualized FC analysis are lacking, and knowledge about the capacity of…

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Altruistic behaviors relieve physical pain [Psychological and Cognitive Sciences]

Engaging in altruistic behaviors is costly, but it contributes to the health and well-being of the performer of such behaviors. The present research offers a take on how this paradox can be understood. Across 2 pilot studies and 3 experiments, we showed a pain-relieving effect of performing altruistic behaviors. Acting…

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Braiding topology and the energy landscape of chromosome organization proteins [Biophysics and Computational Biology]

Assemblies of structural maintenance of chromosomes (SMC) proteins and kleisin subunits are essential to chromosome organization and segregation across all kingdoms of life. While structural data exist for parts of the SMC−kleisin complexes, complete structures of the entire complexes have yet to be determined, making mechanistic studies difficult. Using an…

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Correction for Zhang et al., Elevated signature of a gene module coexpressed with CDC20 marks genomic instability in glioma [Corrections]

MEDICAL SCIENCES Correction for "Elevated signature of a gene module coexpressed with CDC20 marks genomic instability in glioma," by Yunqiu Zhang, Jiuyi Li, Kaikai Yi, Jing Feng, Zhengmin Cong, Zheng Wang, Yanfei Wei, Fan Wu, Wen Cheng, Ayaz Ali Samo, Paolo Salomoni, Qiong Yang, Yu Huang, Chunsheng Kang, Tao Jiang,…

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Sensitivity of self-reported noncognitive skills to survey administration conditions [Economic Sciences]

Noncognitive skills (e.g., persistence and self-control) are typically measured using self-reported questionnaires in which respondents rate their own skills. In many applications—including program evaluation and school accountability systems—such reports are assumed to measure only the skill of interest. However, self-reports might also capture other dimensions aside from the skill, such…

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Sadness, but not all negative emotions, heightens addictive substance use [Psychological and Cognitive Sciences]

Do negative feelings in general trigger addictive behavior, or do specific emotions play a stronger role? Testing these alternative accounts of emotion and decision making, we drew on the Appraisal Tendency Framework to predict that sadness, specifically, rather than negative mood, generally, would 1) increase craving, impatience, and actual addictive…

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Structure and regulation of human epithelial cell transforming 2 protein [Biophysics and Computational Biology]

Epithelial cell transforming 2 (Ect2) protein activates Rho GTPases and controls cytokinesis and many other cellular processes. Dysregulation of Ect2 is associated with various cancers. Here, we report the crystal structure of human Ect2 and complementary mechanistic analyses. The data show the C-terminal PH domain of Ect2 folds back and…

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Evolutionarily conserved peptides coordinate lunar phase and metabolism [Commentaries]

The family of peptides controlling metabolism and reproduction in vertebrate and invertebrate animals has deep evolutionary roots. In vertebrates, the primary peptide controlling sexual differentiation and reproduction is gonadotropin-releasing hormone (GnRH), a decapeptide with "relatives" extending to the alpha factor, a tridecapeptide mating pheromone of yeast (Saccharomyces cerevisiae) (1). Th

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A carbonate-rich lake solution to the phosphate problem of the origin of life [Earth, Atmospheric, and Planetary Sciences]

Phosphate is central to the origin of life because it is a key component of nucleotides in genetic molecules, phospholipid cell membranes, and energy transfer molecules such as adenosine triphosphate. To incorporate phosphate into biomolecules, prebiotic experiments commonly use molar phosphate concentrations to overcome phosphate's poor reactivity with organics in…

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QnAs with H. Michael Shepard and Dennis J. Slamon [QnAs]

On September 10, 2019, the Albert and Mary Lasker Foundation announced that H. Michael Shepard of San Diego-based Biooncology Consultants, Dennis J. Slamon of the University of California, Los Angeles (UCLA), and Axel Ullrich of the Max Planck Institute of Biochemistry in Martinsried, Germany had been awarded the 2019 Lasker–DeBakey…

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Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer [Immunology and Inflammation]

Reprogramming the tumor microenvironment to increase immune-mediated responses is currently of intense interest. Patients with immune-infiltrated "hot" tumors demonstrate higher treatment response rates and improved survival. However, only the minority of tumors are hot, and a limited proportion of patients benefit from immunotherapies. Innovative approaches that make tumors hot can…

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Structure of the cytochrome aa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site [Biochemistry]

Virtually all proton-pumping terminal respiratory oxygen reductases are members of the heme-copper oxidoreductase superfamily. Most of these enzymes use reduced cytochrome c as a source of electrons, but a group of enzymes have evolved to directly oxidize membrane-bound quinols, usually menaquinol or ubiquinol. All of the quinol oxidases have an…

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Optimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapy [Immunology and Inflammation]

Cancer immunotherapies are increasingly combined with targeted therapies to improve therapeutic outcomes. We show that combination of agonistic anti-CD40 with antiangiogenic antibodies targeting 2 proangiogenic factors, vascular endothelial growth factor A (VEGFA) and angiopoietin 2 (Ang2/ANGPT2), induces pleiotropic immune mechanisms that facilitate tumor rejection in several tumor models. On the

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The proton electrochemical gradient induces a kinetic asymmetry in the symport cycle of LacY [Biochemistry]

LacY catalyzes accumulation of galactosides against a concentration gradient by coupling galactoside and H+ transport (i.e., symport). While alternating access of sugar- and H+-binding sites to either side of the membrane is driven by binding and dissociation of sugar, the electrochemical H+ gradient (∆μ∼H+) functions kinetically by decreasing the Km…

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Correction for Yu et al., Wildfire prevention through prophylactic treatment of high-risk landscapes using viscoelastic retardant fluids [Corrections]

APPLIED PHYSICAL SCIENCES Correction for "Wildfire prevention through prophylactic treatment of high-risk landscapes using viscoelastic retardant fluids," by Anthony C. Yu, Hector Lopez Hernandez, Andrew H. Kim, Lyndsay M. Stapleton, Ruben J. Brand, Eric T. Mellor, Cameron P. Bauer, Gregory D. McCurdy, Albert J. Wolff III, Doreen Chan, Craig S….

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Fin ray patterns at the fin-to-limb transition [Evolution]

The fin-to-limb transition was marked by the origin of digits and the loss of dermal fin rays. Paleontological research into this transformation has focused on the evolution of the endoskeleton, with little attention paid to fin ray structure and function. To address this knowledge gap, we study the dermal rays…

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Biotic and anthropogenic forces rival climatic/abiotic factors in determining global plant population growth and fitness [Ecology]

Multiple, simultaneous environmental changes, in climatic/abiotic factors, interacting species, and direct human influences, are impacting natural populations and thus biodiversity, ecosystem services, and evolutionary trajectories. Determining whether the magnitudes of the population impacts of abiotic, biotic, and anthropogenic drivers differ, accounting for their direct effects and effects medi

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Mechanistic insights into the interactions of dynein regulator Ndel1 with neuronal ankyrins and implications in polarity maintenance [Neuroscience]

Ankyrin-G (AnkG), a highly enriched scaffold protein in the axon initial segment (AIS) of neurons, functions to maintain axonal polarity and the integrity of the AIS. At the AIS, AnkG regulates selective intracellular cargo trafficking between soma and axons via interaction with the dynein regulator protein Ndel1, but the molecular…

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Behavioral evidence for geomagnetic imprinting and transgenerational inheritance in fruit flies [Physiology]

Certain long-distance migratory animals, such as salmon and sea turtles, are thought to imprint on the magnetic field of their natal area and to use this information to help them return as adults. Despite a growing body of indirect support for such imprinting, direct experimental evidence thereof remains elusive. Here,…

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Evidence of tool use in a seabird [Evolution]

Documenting novel cases of tool use in wild animals can inform our understanding of the evolutionary drivers of the behavior's emergence in the natural world. We describe a previously unknown tool-use behavior for wild birds, so far only documented in the wild in primates and elephants. We observed 2 Atlantic…

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Australasian impact crater buried under the Bolaven volcanic field, Southern Laos [Earth, Atmospheric, and Planetary Sciences]

The crater and proximal effects of the largest known young meteorite impact on Earth have eluded discovery for nearly a century. We present 4 lines of evidence that the 0.79-Ma impact crater of the Australasian tektites lies buried beneath lavas of a long-lived, 910-km3 volcanic field in Southern Laos: 1)…

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Correction for Wu et al., Machine learning-assisted directed protein evolution with combinatorial libraries [Corrections]

APPLIED BIOLOGICAL SCIENCES, COMPUTER SCIENCES Correction for "Machine learning-assisted directed protein evolution with combinatorial libraries," by Zachary Wu, S. B. Jennifer Kan, Russell D. Lewis, Bruce J. Wittmann, and Frances H. Arnold, which was first published April 12, 2019; 10.1073/pnas.1901979116 (Proc. Natl. Acad. Sci. U.S.A. 116, 8852–8858). The authors note…

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Extreme offspring ornamentation in American coots is favored by selection within families, not benefits to conspecific brood parasites [Evolution]

Offspring ornamentation typically occurs in taxa with parental care, suggesting that selection arising from social interactions between parents and offspring may underlie signal evolution. American coot babies are among the most ornamented offspring found in nature, sporting vividly orange-red natal plumage, a bright red beak, and other red parts around…

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Hazard from Himalayan glacier lake outburst floods [Environmental Sciences]

Sustained glacier melt in the Himalayas has gradually spawned more than 5,000 glacier lakes that are dammed by potentially unstable moraines. When such dams break, glacier lake outburst floods (GLOFs) can cause catastrophic societal and geomorphic impacts. We present a robust probabilistic estimate of average GLOFs return periods in the…

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Middle Holocene expansion of Pacific Deep Water into the Southern Ocean [Earth, Atmospheric, and Planetary Sciences]

The Southern Ocean is a key region for the overturning and mixing of water masses within the global ocean circulation system. Because Southern Ocean dynamics are influenced by the Southern Hemisphere westerly winds (SWW), changes in the westerly wind forcing could significantly affect the circulation and mixing of water masses…

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Gene Therapies Make It to Clinical Trials

#2 in our top science stories of 2019.

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From crab studies, a broader approach to identifying brain cells

In a new study, a team tests the notion that a cell's identity can be described solely by the genes it expresses. The study advocates a more 'multimodal' approach to defining cell identity.

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Combining neurologic and blood pressure drugs reduces breast tumor development in mice

Adding a medication used to treat epilepsy, bipolar disorder and migraines to a blood pressure medicine reversed some aspects of breast cancer in the offspring of mice at high risk of the disease because of the high fat diet fed to their mothers during pregnancy. Conversely, this treatment combination increased breast cancer development in the offspring whose mothers had not been fed a high fat di

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The mysterious case of the ornamented coot chicks has a surprising explanation

The American coot is a somewhat drab water bird with gray and black feathers and a white beak, common in wetlands throughout North America. Coot chicks, however, sport outrageously bright orange and red feathers, skin, and beaks. A new study explains how the bright coloring of coot chicks fits in with the reproductive strategy of their less colorful parents.

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Objective subtle cognitive difficulties predict amyloid accumulation and neurodegeneration

Researchers report that accumulating amyloid protein occurred faster among persons deemed to have 'objectively-defined subtle cognitive difficulties' (Obj-SCD) than among persons considered to be 'cognitively normal,' offering a potential new early biomarker for Alzheimer's disease.

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Novel combination of antibodies leads to significant improvement in cancer immunotherapy

The simultaneous use of antibodies based on two differing mechanisms of action leads to a more effective destruction of tumors. This has been demonstrated by a study in animal models by medical oncologists and scientists. Patients who do not respond to current immunotherapy options could benefit most from this new treatment.

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The Atlantic Daily: Our Culture Desk's Favorite Listening of 2019 ⏯

It's Monday, December 30. In today's issue: First, reflections on the aftermath of Monsey, New York. Plus: Our culture desk's favorite music and podcasts from 2019. (AP) "It's tapping into every fear." A recent machete attack at a rabbi's Hanukkah celebration in Monsey, New York capped a month of brutal anti-Semitic violence. New York State, home to the largest Jewish population outside of Israel

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Reporters Pick Their Favorite Global Stories Of The Decade

The topics range from a ticking time bomb in the Arctic to the art of taking selfies in an ethical way. Here are the stories selected by our contributors. (Image credit: From left: John Poole/NPR; Jason Beaubien/NPR; Courtesy of Be Girl Inc.; SAIH Norway/Screenshot by NPR; Marc Silver/NPR )

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The Most Memorable Family and Education Interviews of the Year

As reporters, we spend a lot of our time learning and synthesizing a whole bunch of new information, trying to figure out what's most important to convey to readers. But every now and again, we hear something during an interview that causes us to stop what we're doing, makes us laugh or weep, or comes back to us when we're off the clock, maybe even days or weeks later. As the year comes to a clos

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A Pop-Culture Time Capsule of the 2010s

In an attempt to do the impossible and sum up the last decade of pop culture in a single list, we gave our writers a prompt: Choose three works or moments that captured the last 10 years for you. First, pick a personal favorite. Second, pick something that mattered to the zeitgeist. Third, name something that offered a warning about what was to come. The result is a completely subjective and hard

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Choose the best streaming device for your needs

When your only window is the size of a two-by-four, sometimes streaming a nature documentary is the best option. (SimpleFoto via Depositphotos/) You've got more music, movies, and shows to pick from than ever before—and an increasing number of gadgets to watch them on. With streaming boxes and streaming sticks galore, it's a congested market. We've spent a lot of time thinking about the best opti

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MRI and 'radiomics' predict the chance breast cancer will return

Using imaging to characterize the genetic makeup of tumors may pave the way for individualized, non-invasive treatment—and could predict a woman's chance of breast cancer recurrence 10 years down the road, researchers report. Diverse diseases like breast cancer can present challenges for clinicians, specifically on a cellular level. While one patient's tumor may differ from another's, the cells w

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Photos of Australia's Raging Bushfires

Southeast Australia's recent extreme weather conditions—record-setting heat and powerful winds—have spawned more than 100 bushfires. These fires recently drove thousands of tourists and locals, cut off from overland escape routes, to seek shelter on nearby beaches. Heavy smoke has reddened skies across Australia's two most populous states, as hundreds of firefighters battle the blazes. Below, a r

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Blazar variability

Active galactic nuclei (AGN) are supermassive black holes at the centers of galaxies that are accreting material. These AGN emit jets of charged particles that move at speeds close to that of light, transporting huge amounts of energy away from the central black hole region and radiating across the electromagnetic spectrum. Blazars are extreme examples of AGN in which the collimated jets are coinc

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eDNA expands species surveys to capture a more complete picture

Tiny bits of DNA collected from waters off the West Coast allowed scientists to identify more species of marine vertebrates than traditional surveys with trawl nets. They also reflect environmental shifts such as unusual ocean temperatures that affect the organisms present, new research shows.

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Lawsuit: Asbestos, mold, fumes make fire station hazardous

A firefighter says asbestos, mold and toxic fumes inside a fire station in Alabama's largest city have sickened him and other firefighters.

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Egypt draws ire with artifacts' move to busy Tahrir Square

Egypt's recent decision to transport ancient Pharaonic artifacts to a traffic circle in the congested heart of Cairo has fueled fresh controversy over the government's handling of its archaeological heritage.

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eDNA expands species surveys to capture a more complete picture

Tiny bits of DNA collected from waters off the West Coast allowed scientists to identify more species of marine vertebrates than traditional surveys with trawl nets. They also reflect environmental shifts such as unusual ocean temperatures that affect the organisms present, new research shows.

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NASA finds Tropical Storm Calvinia moving away from Mauritius

Visible imagery from NASA's Aqua satellite on Dec. 31 revealed that Tropical Cyclone Calvinia had moved south of the island of Mauritius in the Southern Indian Ocean.

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NASA finds a weaker Sarai now a depression

NASA-NOAA's Suomi NPP satellite provided forecasters with an image of Tropical Cyclone Sarai and it showed a much weaker storm near Tonga in the South Pacific Ocean.

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In leap for quantum computing, silicon quantum bits establish a long-distance relationship

In an important step forward in the quest to build a quantum computer using silicon-based hardware, researchers have succeeded in making possible the exchange of information between two qubits located relatively far apart — about the length of a grain of rice, which is a considerable distance on a computer chip. Connecting two silicon qubits across this distance makes possible new and more comple

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Old Wikipedia predictions for the 2010s

As more and more discussions about what the 2020s will be like appear on futurology I thought I would take a look at Wikipedia editors' predictions about the 2010s. Here is the Wikipedia-article from December 31, 2009 . Let's see how accurate some of those predictions had been: World population is likely to reach around 7.5 billion by the end of the decade According to Wikipedia the current world

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Out of every 100 people that make it to 2020, more than 7 will not see 2030.

That is over 590 million people alive now. Maybe even you and I are one of them. Data given on the UN website (given below) shows that 640 million people will die between 2020 and 2030, of which 49.8 million would have born in the same period (ages 1 – 10), which means 640 – 49.8 million people alive today would die that gives us over 590 million people. On a more positive note (depending on your

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Yanis Varoufakis: Imagining a world without capitalism

submitted by /u/My_reddit_strawman [link] [comments]

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A Substance Like Nothing Else on Earth

Amber is precious, but it's not a gem. It's fossilized tree resin—a substance that forms over millions of years, capturing ancient detail as the sap oozes. Amber specimens have led to a "mind-blowing" number of scientific discoveries, the writer Katharine Gammon says. "The amount of detail you can get in fossilized specimens inside the amber is eons ahead of other types of fossils." Why, then, ha

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Around the World, Countries Are Racing to the Moon

#3 in our top science stories of 2019.

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Can We Target Weight Loss to a Specific Part of Our Body?

The truth behind "belly-busting" and other weight loss claims.

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Simple method protects more NICU babies from Staph germs

A relatively simple strategy can reduce the chance of parents exposing their babies in the neonatal intensive care unit to one of the most commonly diagnosed and potentially deadly microbial scourges in a hospital: Staphylococcus aureus . For sick or premature babies spending their first days of life in a hospital's neonatal intensive care unit (NICU), the soothing voice and gentle touch of a lov

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eDNA expands species surveys to capture a more complete picture

Tiny bits of DNA collected from waters off the West Coast allowed scientists to identify more species of marine vertebrates than traditional surveys with trawl nets. They also reflect environmental shifts such as unusual ocean temperatures that affect the organisms present, new research shows.

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Mayo clinic researchers test novel injection of gene therapy vectors into the kidney

Before gene therapy can be used to treat renal diseases, delivery of therapeutic genes to the kidney must become much more efficient.

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Making blood on demand: How far have we come?

The authors conclude the review with a summary of future perspectives, in which they discuss how newly developed techniques, like the deactivated-Cas9 (dCas9) gene-expression control system, can be utilized during the course of hematopoietic differentiation of pluripotent stem cells for precise temporal control of the aforementioned master regulators to achieve functional HSCs.

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Let's Get To It

Another year! And another decade, for that matter. Before Neil DeGrasse Tyson swoops down and tells us all that these are arbitrary calendrical units, I'll stipulate that they are, and that they're still worthwhile opportunities to take stock. So how's drug research going? Honestly, pretty well. We still have a lot of terrible unsolved problems out there, but on that ever-present other hand, ther

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MuttMentor – Smart Dog Collar: Part 2

submitted by /u/smellslikeml [link] [comments]

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What to Expect in the Publishing World in 2020

Publishers' efforts to reduce "leakage," funder-driven open-access schemes, the growth of academic publishing in China, and more.

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Marketing Psychiatric Drugs to Jailers and Judges

On a rainy Monday morning in April, more than a hundred sheriffs, doctors, nurses, and jail guards from around the country sat in a ballroom on the outskirts of Nashville, sipping on coffees and listening to Daniel Potenza, a psychiatrist from New Hampshire, describe one of their most vexing problems: treating schizophrenia. The conference, on medical care inside America's jails and prisons, had

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Did life on Earth start in 'soda lakes'?

New research may solve a problem with some theories of the origins of life on Earth. Life as we know it requires phosphorus. It's one of the six main chemical elements of life, it forms the backbone of DNA and RNA molecules, acts as the main currency for energy in all cells, and anchors the lipids that separate cells from their surrounding environment. But how did a lifeless environment on the ea

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GM golden rice gets landmark safety approval in the Philippines

The Philippines is the first country with a serious vitamin A deficiency problem to approve genetically modified golden rice as safe for humans and animals to eat

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Mass Production of Solid-State xEV Batteries to Begin by 2024

submitted by /u/cake_donut [link] [comments]

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Mysterious Swarms of Giant Drones Have Officials Baffled

Giant Drones On December 24, The Denver Post reported that fleets of up to 17 drones, each with an estimated wingspan of six feet, had been spotted flying over Colorado's Phillips and Yuma counties at night for more than a week. Since then, the sightings have expanded to six counties in Colorado and Nebraska, with as many as 30 drones spotted in the sky at once — and, ominously, no one seems to k

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How fish fins evolved on the way to land-ready limbs

Fossilized fish from the late Devonian period, roughly 375 million years ago, are shedding light on the evolution of fins as they began to transition into limbs fit for walking on land. The study uses CT scanning to examine the shape and structure of fin rays still encased in surrounding rock. The imaging tools allowed the researchers to construct digital 3D models of the entire fin of the fishap

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Trial suggests babies in intensive care can be better protected from parental bacteria

Now, a Johns Hopkins Medicine research team reports it has developed and tested a relatively simple strategy for reducing the chance of parents exposing their babies in the NICU to one of the most commonly diagnosed and potentially deadly microbial scourges in a hospital: Staphylococcus aureus. The researchers detailed the positive findings from their preliminary clinical trial in the Dec. 30, 201

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How the brain balances pleasure and pain

The region of the brain called the ventral pallidum balances signals that either excite or inhibit neurons to influence the motivation of an animal to seek pleasure or avoid pain. An imbalance skews positive vs. negative motivation and may explain behaviors associated with psychiatric disorders like depression or anxiety.

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Chinese Scientist Responsible for Genetically Engineered Babies Gets 3 Years in Prison

The international medical community was aghast last year when a Chinese scientists announced the first ever genetically engineered babies. He Jiankui and his team used the CRISPR/Cas9 gene editing tool to make two twin girls immune to HIV infection but did so without authorization from medical authorities. Now, Chinese state media reports that He Jiankui has been sentenced to three years in priso

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Driverless cars and the other biggest sci and tech fails of the decade

Whether it was driverless cars, lab-grown meat or faster-than-light neutrinos, some things just didn't live up to the hype in the 2010s

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Six photography projects to try in the new year

Kickstart your creativity in the new decade with these photo projects. (Benjamin Combs/Unsplash/) The new year is a great time to get experimental with your photography and try out some new things. For many photographer's it can be a slow time that offers a moment to get your backups, your books, and your goals for the next year in order. All that time also makes it a great place to try your hand

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Betrayed by bile: bile acids help norovirus sneak into cells

Human noroviruses, the leading viral cause of foodborne illness and acute diarrhea around the world, infect cells of the small intestine by piggybacking on a normal cellular process called endocytosis that cells use to acquire materials from their environment.

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What U.S. Intelligence Thought 2020 Would Look Like

In 2004, Mark Zuckerberg launched Facebook. George W. Bush was reelected president of the United States. And American intelligence analysts consulted with hundreds of experts across five continents to try to predict what the world would look like in 2020. The result, a 119-page report by the National Intelligence Council titled "Mapping the Global Future," is an eerie and illuminating read with 2

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The Top Ten Scientific Discoveries of the Decade

Breakthroughs include measuring the true nature of the universe, finding new species of human ancestors, and unlocking new ways to fight disease

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Start Fresh: 6 Tips For Emotional Well-Being In 2020

Joy can be cultivated. Hostility often masks depression. As one year ends and another begins, these six insights and tips from psychologists offer hope for a good new year. (Image credit: Michael Driver for NPR)

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Check out our top 10 posts of the past decade

Over the past decade, Futurity has shared thousands of posts about research discoveries. Here are the 10 that drew in the most readers: 10. Common painkiller doesn't ease chronic pain after nerve injury "Given the rising rates of surgery and shrinking reliance on opioids, it is critical that we understand how to study new drugs that work differently in patients like the ones included in this stud

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NASA finds a weaker Sarai now a depression

NASA-NOAA's Suomi NPP satellite provided forecasters with an image of Tropical Cyclone Sarai and it showed a much weaker storm near Tonga in the South Pacific Ocean.

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NASA finds Tropical Storm Calvinia moving away from Mauritius

Visible imagery from NASA's Aqua satellite on Dec. 31, 2019 revealed that Tropical Cyclone Calvinia had moved south of the island of Mauritius in the Southern Indian Ocean.

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2 ways to deal with invasive species without toxic stuff

Two new studies focus on taking an integrated approach to the management of aquatic invasive species. Though small and somewhat nondescript, quagga and zebra mussels pose a huge threat to local rivers, lakes, and estuaries. Stewards of local waterways, reservoirs, and water recreation areas remain vigilant to the possibility of infestation by these and other non-native organisms. Now, researchers

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Earthshot Prize: William and Kate launch prize to 'repair the Earth'

The Duke and Duchess of Cambridge unveil a global prize to tackle climate issues in the next decade.

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50+ Reasons Our Favorite Emerging Technologies Had an Amazing 2019

For most of history, technology was about atoms, the manipulation of physical stuff to extend humankind's reach. But in the last five or six decades, atoms have partnered with bits, the elemental "particles" of the digital world as we know it today. As computing has advanced at the accelerating pace described by Moore's Law, technological progress has become increasingly digitized. SpaceX lands a

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'Detours' might lead to better batteries

Defects in cathode crystals may speed lithium absorption to create better batteries, electronics, and solar energy storage, researchers report. For a new study in Computational Materials , they show how placing specific defects in the crystalline lattice of lithium iron phosphate-based cathodes broadens the avenues through which lithium ions travel. The theoretical calculations could improve perf

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Let it breed: why desexing dogs isn't always the best thing to do

In pet-loving nations such as Australia, nobody likes the idea of dogs churning out litters in squalid conditions or sitting homeless in a shelter.

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Giant magnetic ropes seen in Whale Galaxy's halo

Using the National Science Foundation's Karl G. Jansky Very Large Array radio telescope, a team of astronomers has captured for the first time an image of large-scale, coherent, magnetic fields in the halo of a faraway spiral galaxy, confirming theoretical modeling of how galaxies generate magnetic fields and potentially increasing knowledge of how galaxies form and evolve.

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Plants model more efficient thermal cooling method

When drops of water touch the surface of a lotus flower leaf, they form beads and roll off, collecting dust particles along the way. In contrast, water droplets on a rose petal also form beads, but remain pinned to the petal's surface. A mechanical engineer at Washington University in St. Louis combined the two concepts to find a more efficient way for droplets to evaporate from a surface.

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New cultures, new experiences: 4 ways to keep kids learning while travelling

The school year is over and holidays are upon us. But that doesn't mean your children's learning experiences can't continue.

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Let it breed: why desexing dogs isn't always the best thing to do

In pet-loving nations such as Australia, nobody likes the idea of dogs churning out litters in squalid conditions or sitting homeless in a shelter.

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Hot and bothered: heat affects all of us, but older people face the highest health risks

Australian summer temperatures have risen by 1.66℃ over the past 20 years. In the past century we've seen a significant increase in the number, intensity and duration of heatwaves during our summers.

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Wildfire modeling helps predict fires in Colombia

A new wildfire model helps predict where and when wildfires will start in the Aburrá Valley of Colombia. This research, presented earlier this month at the 2019 American Geophysical Union Fall Meeting in San Francisco, is helping local cities avoid the devastating environmental and health impacts of fires.

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Topological semimetals can generate sizable transverse thermoelectric figure of merit

Thermoelectric materials can convert temperature difference in a conducting solid into electrical energy, or vice versa. However, the conventional thermoelectric effect, i.e., the longitudinal Seebeck effect, meets some severe limitations in promoting its conversion efficiency. Now, scientists in Chinese Academy of Sciences have found large transverse thermoelectric effect in a topological semimet

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Pharmacies leave customers hanging when it comes to disposing of antibiotics and opioids

A telephone survey conducted by researchers at UC San Francisco found that fewer than half of California pharmacies provided disposal instructions meeting US Food and Drug Administration guidelines, and just 10% followed the FDA's preferred recommendation to take back unused medications from their customers.

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What comes first, beta-amyloid plaques or thinking and memory problems?

The scientific community has long believed that beta-amyloid, a protein that can clump together and form sticky plaques in the brain, is the first sign of Alzheimer's disease. Beta-amyloid then leads to other brain changes including neurodegeneration and eventually to thinking and memory problems. But a new study challenges that theory. The study suggests that subtle thinking and memory difference

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When automotive assembly plants close, deaths from opioid overdoses rise

Closing of local automotive assembly plants may lead to increases in deaths from opioid overdose, according to a study led by researchers at the Perelman School of Medicine at the University of Pennsylvania and the Massachusetts General Hospital. The findings highlight fading economic opportunity as a driving factor in the ongoing national opioid epidemic, and build on previous research that links

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Novel combination of antibodies leads to significant improvement in cancer immunotherapy

The simultaneous use of antibodies based on two differing mechanisms of action leads to a more effective destruction of tumors. This has been demonstrated by a study in animal models by medical oncologists and scientists at the University of Basel that has been published in the scientific journal PNAS. Patients who do not respond to current immunotherapy options could benefit most from this new tr

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Persistent organic pollutants in mother's blood linked to smaller fetal size

Pregnant women exposed to persistent organic pollutants, or POPs, had slightly smaller fetuses than women who haven't been exposed to these chemicals, according to an analysis of ultrasound scans by researchers at the National Institutes of Health and other institutions.

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How fish fins evolved just before the transition to land

Research on fossilized fish details the evolution of fins as they began to transition into limbs fit for walking on land.

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The mysterious case of the ornamented coot chicks has a surprising explanation

The American coot is a somewhat drab water bird with gray and black feathers and a white beak, common in wetlands throughout North America. Coot chicks, however, sport outrageously bright orange and red feathers, skin, and beaks. A new study explains how the bright coloring of coot chicks fits in with the reproductive strategy of their less colorful parents.

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Life could have emerged from lakes with high phosphorus

Life as we know it requires phosphorus, and lots of it. But phosphorus is scarce. A University of Washington study, published Dec. 30 in the Proceedings of the National Academy of Sciences, reports that certain types of carbonate-rich lakes, which could have formed on early Earth, have the right chemistry to keep phosphorous levels high and available to organisms.

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MIV-711 not associated with pain reduction, but may reduce disease progression in osteoarthritis

MIV-711, a novel selective cathepsin K inhibitor, was not more effective than placebo for reducing pain related to knee osteoarthritis. However, MIV-711 significantly reduced bone and cartilage progression. Findings from a randomized, placebo-controlled study are published in Annals of Internal Medicine.

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Fewer than half of California pharmacies provide correct drug disposal info

Fewer than half of California pharmacies provided correct prescription drug disposal details, a percentage that dropped if 'secret shoppers' made their call on a weekend, according to a brief research report published online Dec. 31, 2019, in Annals of Internal Medicine.

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From the archive

Nature, Published online: 31 December 2019; doi:10.1038/d41586-019-03867-9 How Nature reported a successful treatment for rattlesnake bites in 1870, and ambitions to modernize the Indian sugar industry in 1869.

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New study reveals higher microplastics in London air compared to other cities

Researchers from King's have carried out the first study of microplastics in the atmosphere in London to determine what people within the city might be exposed to and where this comes from.

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Image: Hubble views a galaxy with an active center

This swirling mass of celestial gas, dust and stars is a moderately luminous spiral galaxy named ESO 021-G004, located just under 130 million light-years away.

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Rewriting quantum mechanics in their spare time

As students, Jussi Lindgren and Jukka Liukkonen had found one element of their quantum mechanics lectures unsatisfying. "When we were taught physics, there were some fundamental elements you were told were true, and you had to accept they were true without it being shown why," said Jussi Lindgren, "and I didn't really like this".

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Simulations show thousands of lakes in Himalaya Mountains at risk of flooding due to global warming

Three researchers with the University of Potsdam report that thousands of natural lakes in the Himalayas are at risk of bursting their moraines due to global warming and causing flooding downriver. In their paper published in Proceedings of the National Academy of Sciences, Georg Veh, Oliver Korup and Ariane Walz describe simulations they ran on lake models and what they showed.

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The Historian of Moral Revolution

Economists measure economic change and journalists describe political change, but who captures moral change? Who captures the shifts in manners, values, and mores, how each era defines what is admirable and what is disgraceful? Gertrude Himmelfarb, who died at 97 last night, made this her central concern. She was a physician for the national soul. Himmelfarb was born in 1922 and grew up with her

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Opinion: Health Reform in America–Where Are the Scientists?

Medicare for All could expand access to medical interventions–the very goal of biomedical research.

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My Top 10 Columns of the Decade

Cross-Check began a decade ago. Here are columns that the author liked, even if readers didn't — Read more on ScientificAmerican.com

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Scientists link La Niña climate cycle to increased diarrhea

A study finds that spikes in cases of life-threatening diarrhea in young children are associated with La Niña climate conditions. The findings could provide the basis for an early-warning system that would allow public health officials to prepare for periods of increased diarrhea cases as long as seven months ahead of time.

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How do conifers survive droughts? Study points to existing roots, not new growth

As the world warms, a new study is helping scientists understand how coniferous forests may respond to drought. The research addresses a classic question in the field: When conditions are dry for long periods of time, do trees survive by growing new roots to tap water sources, or by relying on established roots that already go deep?

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Reverse your bad habits with just a handful of tiny changes

Fast food is great sometimes, but if you're always eating it, changing your habits could help (Deposit Photos/) The following is an excerpt adapted from Tiny Habits by BJ Fogg. On a work trip to Ghana, Juni (whose sweet tooth was legendary) went looking for a place to buy ice cream at seven a.m. After reminding her that she was in West Africa, her colleagues asked why on earth she wanted ice crea

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Did Honda's CEO Say EVs Make No Sense? Not Exactly

2018 Clarity Electric Honda CEO Takahiro Hachigo says there's no future for EVs. Or maybe he didn't. Comments Hachigo made recently indicate he doesn't see "a dramatic increase in demand for battery vehicles." Much of the confusion comes from analysis / commentary from other media outlets reacting to a recent interview with Automotive News Europe . Hachigo appears, at worst, to be honest in notin

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CoolBitts Launches $2450 PC Immersion Cooling Kit

Immersion cooling manufacturer CoolBitts thinks there might be a market for immersion cooling systems at the ultra-high-end of the market. The company has announced a kit including chassis, coolant, fans, PCIe tray, power meter, pump, radiator, and rear IO panel. Total price? Just $2450 — though the five gallons of EC-120 coolant that you get does typically retail for about $500. There are two ty

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A new breakthrough in developing effective antimalarial drugs

Parasites in the genus Plasmodium, which cause malaria, are transmitted to humans through bites from infected mosquitoes. The parasites manage to acclimatize to these two completely different hosts because the plasticity of their genome enables them to adapt as necessary. Scientists decided to investigate the epigenetic mechanisms behind this plasticity, in particular DNA methylation. They identif

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Seven Books, and a Universe Worth of Perspective

An all-ages reading list to expand the way you look at the world around you

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3D TV Tells You Everything About This Decade's Tech

You don't need special glasses to see what it looks like when smart people run out of ideas.

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Doctors and Suicide

The rate among students, residents and physicians is significantly higher than average—but so-called wellness initiatives can help — Read more on ScientificAmerican.com

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Skomer Island managers seek 'fit and hardy' staff

The Wildlife Trust is looking to recruit a deputy warden and a visitor officer to work on the island.

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The 10 Best Movie Scenes of the 2010s

Every December, I dissect some of my favorite sequences from my favorite movies of the year for a series called "And, Scene." But because it is the end of the decade, I'm instead presenting my favorite moments from 10 of the best films of the 2010s. Many more could have made this list, and some I've written about in years past. What follows are cinematic memories that have stuck with me over 10 y

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From crab studies, a broader approach to identifying brain cells

In a new study, a team born in part at the Neural Systems & Behavior course in Woods Hole tests the notion that a cell's identity can be described solely by the genes it expresses. The study, published in Proceedings of the National Academy of Sciences, advocates a more 'multimodal' approach to defining cell identity.

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Objective subtle cognitive difficulties predict amyloid accumulation and neurodegeneration

Researchers report that accumulating amyloid protein occurred faster among persons deemed to have 'objectively-defined subtle cognitive difficulties' (Obj-SCD) than among persons considered to be 'cognitively normal,' offering a potential new early biomarker for Alzheimer's disease.

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Doctors and Suicide

The rate among students, residents and physicians is significantly higher than average—but so-called wellness initiatives can help — Read more on ScientificAmerican.com

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When auto assembly plants close, opioid deaths rise

When automotive assembly plants close, deaths from opioid overdose may rise, a new study shows. The findings, in JAMA Internal Medicine , highlight fading economic opportunity as a driving factor in the ongoing national opioid epidemic, and build on previous research that links declining participation in the labor force to increased opioid use in the US, researchers say. "Major economic events, s

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Australia's Angry Summer: This Is What Climate Change Looks Like

The catastrophic fires raging across the southern half of the continent are largely the result of rising temperatures — Read more on ScientificAmerican.com

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Australia's Angry Summer: This Is What Climate Change Looks Like

The catastrophic fires raging across the southern half of the continent are largely the result of rising temperatures — Read more on ScientificAmerican.com

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Here Are the Most Beautiful Science GIFs We Discovered in 2019

Enjoy and loop on — Read more on ScientificAmerican.com

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Here Are the Most Beautiful Science GIFs We Discovered in 2019

Enjoy and loop on — Read more on ScientificAmerican.com

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2020 in Science: A SpaceX Bonanza, Lab-Grown Brains, and More

The number of satellites in orbit will double. Lots more people will get Crispr'd. Organoids might demand of bill of rights. No big deal\!

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The 10 Best Artists of a Decade That Atomized Music

Social media platforms toppled the reign of the album. The 2010s were all about singles—rewriting how we metabolize music and the culture that surrounds it.

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The Survival Advantage of Being a Fancy Baby Coot

As adults, American coots have a drab color scheme, with black bodies and white bills. Their chicks, however, have an aesthetic that's part drunk friar, part disheveled lion, and part tequila sunrise. Their faces and bald pates are bright red, while their necks are encircled in scruffy yellow-orange plumes. These garish colors are very strange. Most bird chicks come in dull, camouflaged hues. And

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Nearly quantized conductance plateau of vortex mode in an iron-based superconductor

When a semiconducting nanowire is coupled to a superconductor, it can be tuned to topological quantum states thought to host localized quasiparticles known as Majorana Zero Modes (MZM). MZMs are their own antiparticles, with promising applications in topological quantum computing. Due to particle-antiparticle equivalence, MZMs exhibit quantized conductance at low temperatures. While many theoretic

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Our solar system may have captured 'alien' comets

A new theory could explain the origins of interstellar comets. According to the most popular theory, proposed by Dutch astronomer Jan Oort, during a very early phase of the solar system's formation, the giant planets scattered objects into the outer regions far away from the sun. There, the icy rocks and dust particles formed a kind of cloud. Passing stars may then scatter these objects back into

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Death toll rises as thousands seek shelter from Australian bush fires

Twelve people have died and thousands more have been displaced by three months of bush fires in Australia, as temperatures have soared to 45°C

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Michigan company to test food-delivery robots in Ann Arbor

submitted by /u/izumi3682 [link] [comments]

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Ford sells out first edition of electric SUV Mustang Mach-E

submitted by /u/izumi3682 [link] [comments]

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Paint-AR app invites creatives to make real time animated augmented reality art & holographic VFX for their own games, VR/AR apps, music videos, 3D printing…

The future of AR art is here… albeit early;) Hurry up with those smartphone-killing next-gen AR glasses Apple, Magic Leap! Check out the Paint-AR app for iPhone/iPad (free): https://apps.apple.com/us/app/paint-ar/id1347083887 Paint-AR is a surreal new augmented reality app. Paint, sculpt, add holograms & live FX. Remix reality & open portals between real & virtual worlds. 3D print or export you

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AI designed, synthesised and validated new drug in 46 days

submitted by /u/Truetree9999 [link] [comments]

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Death toll rises as thousands seek shelter from Australian bushfires

Twelve peopled have died and thousands more have been displaced by three months of bushfires in Australia, as temperatures have soared to 45°C

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#2: Billionaire warlords: Why the future is medieval | Top 10 2019

Big Think's second most popular video of 2019 asks: Russia? China? No. The rising world superpower is the billionaire class. Our problem, says Sean McFate, is that we're still thinking in nation states. Nation states have only existed for the last 300-400 years. Before that, wealthy groups – tribes, empires, aristocracies, etc – employed mercenaries to wage private wars. As wealth inequality reac

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The Most Dangerous People on the Internet This Decade

In the early aughts the internet was less dangerous than it was disruptive. That's changed.

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John Lewis and the Fight That Can't Be Won

John Lewis is dying. On Sunday, the congressman and civil-rights icon disclosed a diagnosis of Stage 4 pancreatic cancer. In his public statement , his tenor remained characteristically triumphant, even optimistic: "I have been in some kind of fight—for freedom, equality, basic human rights—for nearly my entire life. I have never faced a fight quite like the one I have now." He added, "I have dec

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Strange Superconductor Sends Electrons Both Ways

A new material's strange properties could be useful in future quantum computers — Read more on ScientificAmerican.com

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Extending El Niño event predictions to a year

A group of researchers from the Potsdam Institute for Climate Impact Research, Beijing Normal University and Justus-Liebig-Universität Giessen has found a way to predict El Niño events up to a year before they occur. In their paper published in the Proceedings of the National Academy of Sciences, the group describes their complexity-based approach to better predicting the seemingly random weather

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Aviation chief criticises Greta Thunberg and 'flight-shaming' movement

The aviation industry is planning a pushback against the flight-shaming movement and Greta Thunberg, according to the head of the International Air Transport Association

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Radiophysicists study the properties of composites for 5G devices

TSU radiophysicists are forming a database of properties of composite materials that can be used to create 5G and space communication devices operating in the terahertz range. The scientists are creating composite materials from ABS plastic and nanotubes and measuring their properties in a frequency range from 10 MHz to 1 THz.

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Wind conditions influence water circulation and carbon dioxide concentrations in the Southern Ocean

The sea encircling Antarctica acts as a huge mixer for water from all the ocean basins—and this circulating pattern influences the exchange of carbon dioxide (CO2) between the ocean and the atmosphere. A study by an international team of researchers led by Dr. Torben Struve from the University of Oldenburg's Institute for Chemistry and Biology of the Marine Environment (ICBM) has now established t

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China's different shades of greening

Nature, Published online: 31 December 2019; doi:10.1038/d41586-019-03940-3

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The quest for top female academics — a search and destroy mission?

Nature, Published online: 31 December 2019; doi:10.1038/d41586-019-03939-w

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Earthquake prediction: heed the signs and save lives

Nature, Published online: 31 December 2019; doi:10.1038/d41586-019-03941-2

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Testosterone's role in ovulation

Nature, Published online: 31 December 2019; doi:10.1038/d41586-019-03942-1

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How to Travel With Medical Marijuana

Even as more states allow medical marijuana, traveling between states with cannabis can leave patients in legal limbo.

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A look back at Retraction Watch in 2019 — and forward to our 10th anniversary

In August 2020, Retraction Watch will turn 10 — a milestone we still can't quite wrap our minds around. When we started the blog in 2010, we thought we might have enough material for a post or two a month. Little did we know that our little side gig would eventually lead to the world's … Continue reading

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Year in a word: CBD

The cannabis compound is being added to everything from face cream to dog food

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Biologists use the Aeroschup to clean plastic from water

The Aeroschup technology created by TSU biologists to clean petroleum products from the bottom of reservoirs will be used to solve the problem of plastic contamination. The project team has already completed laboratory tests that confirmed the ability of the Aeroschup to extract plastic particles from bottom sediments. The team plans to conduct field tests of the technology in the summer of 2020.

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How nanoparticles from the environment enter the brain

A group of scientists from the Russian Academy of Sciences (ICG SB RAS) and the TSU Biological Institute has established a path through which nanoparticles of viruses and organic and inorganic substances from the environment enter the brain. Additionally, the researchers report a simple and inexpensive way to block their entry. The data obtained by the project could play a large role in medicine a

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Student creates a spray for flash disinfecting of institutions

Alexander Buzaev, a young scientist at the TSU Faculty of Chemistry, is developing a photocatalytic coating for disinfecting indoor surfaces in hospitals, schools, kindergartens, and other institutions. The substance, which forms a very thin film without color or odor, could be used to protect against bacteria.

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The Demagogue's Cocktail of Victimhood and Strength

Editor's Note: This article is part of our "Democracy Undone" series about the erosion of liberal democracy around the world. WARSAW—For the European demagogue, victimhood and strength go hand in hand. In the agitators' worldview, a host of powerful forces—domestic and foreign—is targeting their people, their nation, and their values; and only a single leader, or party, has a chance of holding of

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How Small European Allies See Trump

During my three and a half decades as a career American diplomat, I served as ambassador to Russia and Jordan. Every year, I was responsible for thousands of cables back to the State Department and other readers in the U.S. government, reporting on the efforts of diplomats in our embassy to promote American interests and on developments in the country where we were posted. On relatively rare occa

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The Decade in Which Everything Was Great But Felt Terrible

If I had to pick the story that best captured the economy of the 2010s, it might be the tale of CamperForce : a group of elderly nomads, living in vans and RVs, spending their twilight years temping at Amazon fulfillment centers. There's a positive spin to the story. Some people want the structure and community that work can provide well into retirement age. They may want the freedom and mobility

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Dinosaurs Come Back To Life At The Smithsonian (Rebroadcast)

Life uh, uh, uh, finds a way. (Image credit: Gabrielle Healy/WAMU)

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Pejlevognen er fyldt 50 år: Var det hele bare bluff?

PLUS. Den skræmmende vogn, som udpegede sortseere, har rundet et skarpt hjørne. Vi ser tilbage på starten sammen med manden, der introducerede vognen til Danmark.

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