Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans [Biochemistry]
Feline infectious peritonitis virus (FIPV) is an alphacoronavirus that causes a nearly 100% mortality rate without effective treatment. Here we report a 3.3-Å cryoelectron microscopy (cryo-EM) structure of the serotype I FIPV spike (S) protein, which is responsible for host recognition and viral entry. Mass spectrometry provided site-specific compositions of…
22h
Trump Rule Would Exclude Climate Change in Infrastructure Planning
The administration will propose that federal agencies be allowed to disregard climate change when assessing the environmental effects of major projects.
1d
Watching Pornography Can 'Rewire' The Brain to a More Juvenile State, Says Scientist
There are neurological consequences.
1h
Sustainable supply of minerals and metals key to a low-carbon energy future
submitted by /u/ngt_ [link] [comments]
2h
The Decade of Mars: How the 2020s May Be a New Era of Red Planet Exploration
submitted by /u/lughnasadh [link] [comments]
2h
Why the quantum internet should be built in space – The best way to distribute quantum entanglement around the globe is via a massive constellation of orbiting satellites, physicists say.
submitted by /u/ngt_ [link] [comments]
2h
Fresh Cambridge Analytica leak 'shows global manipulation is out of control' – More than 100,000 documents relating to work in 68 countries that will lay bare the global infrastructure of an operation used to manipulate voters on "an industrial scale" – a dystopian approach to mass mind control?
submitted by /u/mvea [link] [comments]
2h
Australia's bushfires push countless species to extinction – ecologists fear the bushfires represent the catastrophic beginning of a bleak future for the country's native flora and fauna. "It feels like we have hit a turning point that we predicted was coming as a consequence of climate change".
submitted by /u/mvea [link] [comments]
2h
US limits AI exports over fears it will fall into Chinese hands – Companies will need a license to send certain software abroad.
submitted by /u/mvea [link] [comments]
2h
Geoengineering Wouldn't Be Enough to Stop Greenland From Melting – if the world pumped particles high into the atmosphere that would reflect sunlight back into space, it would bring down the global average temperature, but would not stop the melting of the ice sheet, finds new study.
submitted by /u/mvea [link] [comments]
2h
What do you think will be the biggest changes in the next decade REALISTICALLY?
With this being an overall optimistic and (not particularly grounded) sub, many predictions tend to be overly optimistic and sensationalist. if you guys crank up the skepticism, what do you think will be the biggest things in the next decade? submitted by /u/beti88 [link] [comments]
2h
Airbnb claims its AI can predict whether guests are psychopaths
submitted by /u/lughnasadh [link] [comments]
2h
Microbes from humics lakes surprise – bacteria and algae produced omega-3 fatty acids from microplastics
The environmental fate of microplastics has been difficult to trace. A research group used carbon isotope labeling to follow the fate of polyethylene in the food chain. To the researchers surprise, plastic carbon was transformed into beneficial fatty acids, omega-3 and omega-6, by the microbes originating from humic lakes.
4h
Kids twice as likely to eat healthy after watching cooking shows with healthy food
Television programs featuring healthy foods can be a key ingredient in leading children to make healthier food choices now and into adulthood. A new study found kids who watched a child-oriented cooking show featuring healthy food were 2.7 times more likely to make a healthy food choice than those who watched a different episode of the same show featuring unhealthy food.
4h
Bile acids may help regulate gut immunity and inflammation
Could bile acids — the fat-dissolving juices churned out by the liver and gallbladder — also play a role in immunity and inflammation? The answer appears to be yes, according to two separate studies.
4h
Supercharging tomorrow: World's most efficient lithium-sulfur battery
Researchers are on the brink of commercializing the world's most efficient lithium-sulfur (Li-S) battery, which could outperform current market leaders by more than four times.
4h
The Time of Giants
Envisioning the Jurassic world requires a lot of fossil detective work — Read more on ScientificAmerican.com
4h
Study explains why some creams and cosmetics may cause a skin rash
Some compounds found in many personal care products displace natural fat-like molecules in skin cells, which may explain how they cause an allergic skin rash.
5h
Clusters of gold atoms form peculiar pyramidal shape
Freestanding clusters of twenty gold atoms take the shape of a pyramid, researchers discovered. This is in contrast with most elements, which organize themselves by forming shells around one central atom.
5h
The Soleimani Strike Defied the U.S. Constitution
The drone strike that killed Major General Qassem Soleimani, leader of the Quds Force of the Islamic Revolutionary Guard Corps, raises many legal issues, but one of the most significant—at least to the American constitutional order—is that President Donald Trump ordered the strike without so much as informing Democratic leadership in Congress, disregarding Congress's essential role in initiating
5h
2020 SkS Weekly Climate Change & Global Warming News Roundup #1
A chronological listing of news articles linked to on the Skeptical Science Facebook Page during the past week, i.e., Sun, Dec 29, 2019 through Sat, Jan 4, 2020 Editor's Pick There Is No Safe Global Warming Australia Bushfire – Shutterstock Safety is something we all crave. It's human nature. And so perhaps it's not surprising that we've spent the past decade or so outlining what a "safe" level o
5h
DARPA gets back to work on developing autonomous ships as Navy pushes for unmanned fleets
submitted by /u/Publicize [link] [comments]
5h
This Robot Arm Learned To Assemble Objects It Hasn't Seen Before
submitted by /u/Danj_memes_ [link] [comments]
5h
Physicist's theory shows it's possible to time travel by twisting light into a long, fast-rotating cylinder without violating the rules of General Relativity. But travelers can only go back to when the machine was turned on, and they probably won't be able to change the past.
submitted by /u/chicompj [link] [comments]
5h
CES 2020: What to expect – Consumer Electronics Show 2020 starts Jan. 6
submitted by /u/moon-worshiper [link] [comments]
5h
2019 fusion progress at Tokamak Energy–And how 21st century supercomputing and narrow AI is helping.
submitted by /u/izumi3682 [link] [comments]
5h
Climate change now detectable from any single day of weather at global scale
submitted by /u/lughnasadh [link] [comments]
5h
The case of the elusive Majorana: The so-called 'angel particle' is still a mystery
A 2017 report of the discovery of a particular kind of Majorana fermion — the chiral Majorana fermion, referred to as the 'angel particle' — is likely a false alarm, according to new research.
5h
Research identifies changes in neural circuits underlying self-control during adolescence
Researchers applied tools from network science to identify how anatomical connections in the brain develop to support neural activity underlying executive function.
5h
Female chimps' reproductive success decreases in times of strong territorial conflict
Territorial conflicts can turn violent in humans and chimpanzees, two extremely territorial species. An international team of researchers has studied the effects of territoriality on female reproductive success in wild Western chimpanzees and found that high neighbor pressure at times when females typically reproduce can lead to reproductive delays with longer intervals between births. Having many
5h
Study finds dopamine, biological clock link to snacking, overeating and obesity
A new study finds that the pleasure center of the brain and the brain's biological clock are linked, and that high-calorie foods — which bring pleasure — disrupt normal feeding schedules, resulting in overconsumption.
5h
Tests measure solar panel performance beyond established standards
In testing solar panels, the sun's intensity, the spectral composition and the angle of light are important factors in understanding why certain panels are successful and others degrade more quickly. To address the knowledge gap in degradation mechanisms for various photovoltaic types, researchers performed tests over five years in which they collected weather data and panel performance informatio
5h
Shock, fear and sadness grip Australia's 'bushfire refugees'
Thousands of Australians forced from their homes by rampaging bushfires now find themselves stuck in makeshift camps, fearful for the future and turned refugees in their own country.
5h
Spectroscopy: A fine sense for molecules
Scientists have developed a unique laser technology for the analysis of the molecular composition of biological samples. It is capable of detecting minimal variations in the chemical make up of organic systems.
6h
New radiotracer offers opportunities for earlier intervention after heart attack
A new radiotracer can effectively image fibroblast activation after a heart attack, identifying a window of time during which cardiac fibrosis can be prevented and the disease course altered.
6h
A crack team is just the start for civil service reform
The UK prime minister's chief adviser Dominic Cummings wants to recruit new skills
6h
These Are the Biggest Climate Questions for the New Decade
The 2010s brought major climate science advances, but researchers still want to pin down estimates of Arctic melt and sea level rise — Read more on ScientificAmerican.com
7h
The Rise of Fake News. A Machine Learning challenge
submitted by /u/lughnasadh [link] [comments]
8h
We are a new climate change media channel, and are starting by discussing the recent #teamtrees movement, analysing if this a sustainable way to combat climate change and discussing tree planting methods in general. We have analysed some recent research papers in the topic and discussed these too.
submitted by /u/Caaaam [link] [comments]
8h
The Year's Most Fascinating Tech Stories From Around the Web
submitted by /u/dwaxe [link] [comments]
8h
Scientists Find Evidence a Strange Group of Quantum Particles Are Basically Immortal
submitted by /u/izumi3682 [link] [comments]
8h
Sex toys, giant TVs and Alexa in everything: The biggest trends to watch for at CES 2020
submitted by /u/izumi3682 [link] [comments]
8h
Wellbeing: six ways to put a smile back on your face in 2020
The best ways to improve your happiness and inner worth, from expressive writing to self-affirmation "Be always at war with your vices, at peace with your neighbours, and let each new year find you a better man," wrote Benjamin Franklin, a lifelong advocate of self-improvement, in 1755. As 2020 kicks off, many of us will be taking a leaf out of Franklin's book. Unfortunately, many new year's reso
8h
Performance benchmark for quantum computers
Researchers have developed a quantum chemistry simulation benchmark to evaluate the performance of quantum devices and guide the development of applications for future quantum computers.
9h
What Are 'Natural Flavors'?
Are natural flavors actually natural? And what does the designation mean?
9h
Airbnb Claims Its AI Can Predict Whether Guests Are Psychopaths
Problem Predictor To protect its hosts, Airbnb is now using an AI-powered tool to scan the internet for clues that a guest might not be a reliable customer. According to patent documents reviewed by the Evening Standard , the tool takes into account everything from a user's criminal record to their social media posts to rate their likelihood of exhibiting "untrustworthy" traits — including narcis
9h
Space Photos of the Week: Postcards From a Martian Winter
NASA's HiRise camera captures white carbon dioxide frost on a scarlet wonderland.
9h
The Top 10 Weather and Climate Stories of 2019
Near-record Arctic melting, a bountiful but deadly monsoon and three highly destructive tropical cyclones highlight the earth's second warmest year on record — Read more on ScientificAmerican.com
9h
The Year's Most Fascinating Tech Stories From Around the Web
Last Saturday we took a look at some of the most-read Singularity Hub articles from 2019 . This week, we're featuring some of our favorite articles from the last year. As opposed to short pieces about what's happening, these are long reads about why it matters and what's coming next. Some of them make the news while others frame the news, go deep on big ideas, go behind the scenes, or explore the
9h
Starting point for designing drugs that cure clostridium difficile
A new article details a research breakthrough that provides a promising starting point for scientists to create drugs that can cure C. diff — a virulent health care-associated infection that causes severe diarrhea, nausea, internal bleeding, and potentially death.
10h
Researchers build a particle accelerator that fits on a chip
For the first time, scientists have created a silicon chip that can accelerate electrons — albeit at a fraction of the velocity of the most massive accelerators — using an infrared laser to deliver, in less than a hair's width, the sort of energy boost that takes microwaves many feet.
10h
Margrethe Vestager: Kunstig intelligens skal belyse – ikke beslutte
PLUS. AI skal tøjles til Europas fordel og formes efter Europas vision, så det fortsat er mennesker og ikke maskiner, der bestemmer. EU-kommissær Margrethe Vestager har fået 100 dage til at finde frem til hvordan.
10h
The Army Bans TikTok
A million-dollar email scam, a Chinese hacking campaign, and more of the week's top security news.
10h
We're Finally Getting a Filmed Version of 'The Subtle Knife'
The second season of HBO's 'His Dark Materials' promises to bring the second book in Philip Pullman's series to life.
10h
In Case You Missed It
Top news from around the world — Read more on ScientificAmerican.com
10h
My latest explainer video deep diving into the causes and implications of ingroup bias
submitted by /u/hsnaras [link] [comments]
11h
It Wasn't the Law That Stopped Other Presidents From Killing Soleimani
Just about nobody in Washington wants to defend Qassem Soleimani—even if they condemn his killing. He was a terrorist kingpin; he destroyed the lives of countless people across an entire region for more than a decade; he had Syrian, Iraqi, Yemeni, Lebanese, and American blood on his hands. Democratic Senator Chris Murphy slammed what he called an assassination as he tweeted , "Soleimani was an en
11h
Weekend reads: Advice from an author with 18 retractions; 'TripAdvisor for peer review'; theft, indictments, and prison
Before we present this week's Weekend Reads — the first of 2020! — a question: Do you enjoy our weekly roundup? If so, we could really use your help. Would you consider a tax-deductible donation to support Weekend Reads, and our daily work? Thanks in advance. The week at Retraction Watch featured: The retraction of a … Continue reading
11h
AI and tech being used to address root causes of homelessness and predict solutions
submitted by /u/TheJaquiLee [link] [comments]
11h
After Indonesia's deadly floods, few hear climate 'wake up call'. At least 53 people were killed after the rains on New Year's Day, Indonesian authorities said on Saturday. Nearly 175,000 people remain evacuated from their homes.
submitted by /u/Wagamaga [link] [comments]
11h
AI-Generated Articles Entitled to Copyright Protection
submitted by /u/Arzu_1982 [link] [comments]
11h
China ramps up tech education to become artificial intelligence leader
submitted by /u/Arzu_1982 [link] [comments]
11h
Your Next Salad Could Be Grown by a Robot
submitted by /u/Arzu_1982 [link] [comments]
11h
Ads can now be "inserted" into films and television shows streamed online using AI to recognise objects in a scene and spot slots where branded goods and posters can be added without looking out of place, ultimately tailoring product placements to individual viewers' interests.
submitted by /u/mvea [link] [comments]
11h
Lethal algae blooms – an ecosystem out of balance: Toxic formations across the US and the Baltic are part of a worrying trend linked to the climate crisis and farming methods, becoming more common into the future
submitted by /u/mvea [link] [comments]
11h
Physicist Proposes Turning the Sun Into a Gigantic Engine – "That's the new result of the paper: What exactly is possible if you have a Dyson sphere and you want to use it to drive a jet to push a star around?"
submitted by /u/mvea [link] [comments]
11h
This startup is raising $7 million for a technology that can authenticate people based on their typing style – TypingDNA asserts that the typing pattern recognition technology it has developed has an accuracy rate of between 99% and upwards of 99.9%.
submitted by /u/mvea [link] [comments]
11h
The Former CEO of Nissan Was Likely Smuggled Out of Japan
The Japanese government still doesn't know exactly how Carlos Ghosn, who was under house arrest, managed to flee to Lebanon.
11h
New Particle Accelerator Fits on a Silicon Chip
The device uses lasers to accelerate electrons along an etched channel — Read more on ScientificAmerican.com
11h
New Particle Accelerator Fits on a Silicon Chip
The device uses lasers to accelerate electrons along an etched channel — Read more on ScientificAmerican.com
11h
Australia Will Lose to Climate Change
Australia is caught in a climate spiral. For the past few decades, the arid and affluent country of 25 million has padded out its economy—otherwise dominated by sandy beaches and a bustling service sector—by selling coal to the world. As the East Asian economies have grown, Australia has been all too happy to keep their lights on. Exporting food, fiber, and minerals to Asia has helped Australia a
12h
Hope, Happiness And Social Connection: Hidden Benefits Of Regular Exercise
A new book, The Joy of Movement, offers more motivation to exercise. It's not just about getting fit or looking good: Exercise can give you courage, pleasure and better friendships. (Image credit: Boris Austin/Getty Images)
12h
CES 2020 Trends We're Expecting: 5G, E-Scooters, Foldables, Privacy
The annual consumer tech showcase will be awash in shiny gadgets, but it's what those products tell us about the future that matters most.
12h
How to Secure Your Wi-Fi Router and Protect Your Home Network
Router security has improved a bunch in recent years, but there are still steps you can take to lock yours down even better.
12h
NASA Has Reportedly Proposed Taking Japanese Astronauts to The Moon
A global collaboration could be in the works.
13h
The Blueprint Iran Could Follow After Soleimani's Death
The Iranian government's swift pledge to avenge the Trump administration's killing of its infamous military commander Qassem Soleimani, and the U.S. government's deployment of thousands of additional troops to the Middle East and urgent call for Americans to leave Iraq, has left a distinct impression: that some fearsome Iranian retaliation is coming any minute and that it could quickly spiral int
13h
Trump Is Playing Chess One Turn at a Time
Few who served in Iraq, or who had a loved one serving there, can avoid a spasm of gratification at learning that an American drone blew up Qassem Soleimani and half a dozen of his henchmen. The Iranian general's hands were covered with the blood of thousands—Americans, Iraqis, Iranians, Israelis, and their allies. As Carl von Clausewitz wrote, because war involves violence, the emotions cannot h
13h
Imagining a Better End to The Rise of Skywalker
This post contains spoilers for Star Wars: The Rise of Skywalker. Earlier this week, the actor John Boyega riled up Star Wars fans by pointing out that in the Galaxy Far, Far Away, love is rarely kind. "Star Wars romance 😗👀🙂," he tweeted , along with images of Rey and Kylo Ren—the hero and (mostly) villain of Disney's trilogy that just concluded —battling. In one picture from the latest film,
13h
Museet, hvor alle kan se ind i fremtiden, er blevet en turistmagnet
Et museum for ting, som sker om 100 eller 1000 år – Berlins nye attraktion er allerede blevet byens nye turistmagnet.
13h
Ikke længere i tvivl: Dværg-art var i virkeligheden en teenage t-rex
Ny undersøgelse viser, at de små t-rex'er, som man tidligere troede var en ny art, i stedet er t-rex'er i voksealderen.
13h
Why the quantum internet should be built in space
The best way to distribute quantum entanglement around the globe is via a massive constellation of orbiting satellites, physicists say.
13h
Brain in love: The science of attachment in relationships
With evolution came the brain circuitry for feelings of deep attachment to a partner. This circuitry changes within the duration of a relationship, and feelings of attachment grow over time. In a healthy relationship, that attachment system sustains itself even through hard times.
13h
The Other Reason Republicans Won't Cross Trump
If President Donald Trump is booted from office, the catalyst looks certain to be the November election, not impeachment. The Senate has yet to convene an impeachment trial, and the recent killing of an Iranian general could further complicate lawmakers' timing. But with a GOP firewall in the chamber holding firm, Trump's acquittal seems preordained, even though plenty of Republicans appear uneas
14h
After Indonesia's deadly floods, few hear climate 'wake up call'. At least 53 people were killed after the rains on New Year's Day, Indonesian authorities said on Saturday. Nearly 175,000 people remain evacuated from their homes.
submitted by /u/Wagamaga [link] [comments]
14h
Engineers have developed a mineral-coated sand that can soak up toxic metals like lead and cadmium from water. Along with its ability to destroy organic pollutants like bisphenol A (BPA), this material could help cities tap into stormwater, an abundant but underused water source.
submitted by /u/mvea [link] [comments]
14h
Elon Musk: The City of the Future
submitted by /u/mind_bomber [link] [comments]
14h
Most Popular Websites from 1991 to 2020 on a visualisation timeline or race chart
submitted by /u/hassaneliwa [link] [comments]
14h
480,464 citizens of Arizona have signed a state initiative to create a state constitutional amendment that would require 50% of electricity to come from renewable sources by 2030.
submitted by /u/rmanila [link] [comments]
14h
How I learned to love the real Neil Armstrong and embrace the space race | Maggie Aderin Pocock
The Apollo 11 commander taught me to look beyond the stereotype of astronauts as simply white, male daredevils • Dr Maggie Aderin-Pocock is a space scientist and presenter of the Sky at Night Throughout 2019, many of us indulged in a sort of moon madness as we relived the historic moment, on 20 July 1969, when Neil Armstrong stepped out on to the lunar surface and uttered the now immortal words: "
15h
De store virksomheder opretter egne kurser – hvad gør de små?
PLUS. Små og mellemstore virksomheder risikerer at sakke bagud, frygter IDA, som vil satse på mere faglig efteruddannelse til ingeniører.
16h
60 dead in landslides, flash floods in Indonesia's capital
Landslides and floods triggered by torrential downpours have left at least 60 people dead in and around Indonesia's capital, as rescuers struggled to search for people apparently buried under tons of mud, officials said Saturday.
17h
Power supply fears as troops called to battle Australia bushfires (Update)
Skies turned black and ash rained down as fires raged across southeastern Australia on Saturday, threatening power supplies to major cities and prompting the call-up of 3,000 military reservists.
17h
Forskere slår fast: Unikt havdyr kan se uden øjne
Som det kun andet kendte væsen i dyreriget kan en slangestjerneart se, selv om det ikke har øjne.
18h
This wireless power startup says it can charge your phone using only radio waves – Guru is promising a bold future without wires
submitted by /u/mvea [link] [comments]
18h
Kig op! 2020-himlen er klar med otte store astronomiske begivenheder – og én menneskeskabt
I år kan du blandt andet se to sammensmeltede planeter og et 'satellit-tog'.
18h
Part of Real Paleo Diet: It's a Tuber
In South Africa archaeologists found the charred remains of a roasted root vegetable. Christopher Intagliata reports.
18h
Part of Real Paleo Diet: It's a Tuber
In South Africa archaeologists found the charred remains of a roasted root vegetable. Christopher Intagliata reports. — Read more on ScientificAmerican.com
20h
Identification and characterization of extrachromosomal circular DNA in maternal plasma [Medical Sciences]
We explored the presence of extrachromosomal circular DNA (eccDNA) in the plasma of pregnant women. Through sequencing following either restriction enzyme or Tn5 transposase treatment, we identified eccDNA molecules in the plasma of pregnant women. These eccDNA molecules showed bimodal size distributions peaking at ∼202 and ∼338 bp with distinct…
22h
Highly efficient binary copper-iron catalyst for photoelectrochemical carbon dioxide reduction toward methane [Chemistry]
A rational design of an electrocatalyst presents a promising avenue for solar fuels synthesis from carbon dioxide (CO2) fixation but is extremely challenging. Herein, we use density functional theory calculations to study an inexpensive binary copper−iron catalyst for photoelectrochemical CO2 reduction toward methane. The calculations of reaction energetics suggest that…
22h
Fast oxidation of sulfur dioxide by hydrogen peroxide in deliquesced aerosol particles [Earth, Atmospheric, and Planetary Sciences]
Atmospheric sulfate aerosols have important impacts on air quality, climate, and human and ecosystem health. However, current air-quality models generally underestimate the rate of conversion of sulfur dioxide (SO2) to sulfate during severe haze pollution events, indicating that our understanding of sulfate formation chemistry is incomplete. This may arise because…
22h
The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia [Cell Biology]
The circadian clock regulates many aspects of immunity. Bacterial infections are affected by time of day, but the mechanisms involved remain undefined. Here we show that loss of the core clock protein BMAL1 in macrophages confers protection against pneumococcal pneumonia. Infected mice show both reduced weight loss and lower bacterial…
22h
Translation of the intrinsically disordered protein {alpha}-synuclein is inhibited by a small molecule targeting its structured mRNA [Biochemistry]
Many proteins are refractory to targeting because they lack small-molecule binding pockets. An alternative to drugging these proteins directly is to target the messenger (m)RNA that encodes them, thereby reducing protein levels. We describe such an approach for the difficult-to-target protein α-synuclein encoded by the SNCA gene. Multiplication of the…
22h
Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments [Biophysics and Computational Biology]
Members of the cofilin/ADF family of proteins sever actin filaments, increasing the number of filament ends available for polymerization or depolymerization. Cofilin binds actin filaments with positive cooperativity, forming clusters of contiguously bound cofilin along the filament lattice. Filament severing occurs preferentially at boundaries between bare and cofilin-decorated (cofilactin) segmen
22h
The effector mechanism of siRNA spherical nucleic acids [Biochemistry]
Spherical nucleic acids (SNAs) are nanostructures formed by chemically conjugating short linear strands of oligonucleotides to a nanoparticle template. When made with modified small interfering RNA (siRNA) duplexes, SNAs act as single-entity transfection and gene silencing agents and have been used as lead therapeutic constructs in several disease models. However,…
22h
Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiation [Biochemistry]
Translation initiation controls protein synthesis by regulating the delivery of the first aminoacyl-tRNA to messenger RNAs (mRNAs). In eukaryotes, initiation is sophisticated, requiring dozens of protein factors and 2 GTP-regulated steps. The GTPase eIF5B gates progression to elongation during the second GTP-regulated step. Using electron cryomicroscopy (cryo-EM), we imaged an…
22h
The rhizobial autotransporter determines the symbiotic nitrogen fixation activity of Lotus japonicus in a host-specific manner [Plant Biology]
Leguminous plants establish endosymbiotic associations with rhizobia and form root nodules in which the rhizobia fix atmospheric nitrogen. The host plant and intracellular rhizobia strictly control this symbiotic nitrogen fixation. We recently reported a Lotus japonicus Fix− mutant, apn1 (aspartic peptidase nodule-induced 1), that impairs symbiotic nitrogen fixation. APN1 encodes…
22h
NK cells clear {alpha}-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of {alpha}-synucleinopathy [Neuroscience]
The pathological hallmark of synucleinopathies, including Lewy body dementia and Parkinson's disease (PD), is the presence of Lewy bodies, which are primarily composed of intracellular inclusions of misfolded α-synuclein (α-syn) among other proteins. α-Syn is found in extracellular biological fluids in PD patients and has been implicated in modulating immune…
22h
Present-day drivers do not explain biodiversity patterns in mammals [Commentaries]
Mammals are an obvious choice for analyses of global biodiversity patterns. They are not too diverse, disproportionately well studied, and even nonspecialists will be interested in the results. They are also fairly good indicators of overall vertebrate diversity (1). Moreover, the limited ability of most mammals to cross oceanic barriers…
22h
Global shape of Toll activation is determined by wntD enhancer properties [Developmental Biology]
Buffering variability in morphogen distribution is essential for reproducible patterning. A theoretically proposed class of mechanisms, termed "distal pinning," achieves robustness by combining local sensing of morphogen levels with global modulation of gradient spread. Here, we demonstrate a critical role for morphogen sensing by a gene enhancer, which ultimately determines…
22h
Linking calcium signaling and mitochondrial function in fungal drug resistance [Commentaries]
The host range for Aspergillus fumigatus is wide, including mammals, aves, and insecta (stonebrood). This is linked to the significant adaptability of this important fungal pathogen. It is thermotolerant, able to grow up to 70 °C, and astonishingly also remains viable down to −20 °C (1). It is microaerophilic and…
22h
A Massive 'Blob' of Hot Water Is Threatening New Zealand's Marine Life
Scientists don't have an explanation for it.
23h
Dr. Heather Ashton, 90, Dies; Helped People Quit Anxiety Drugs
Her "Ashton Manual," published in 1999, has become a cornerstone for people all over the world dealing with benzodiazepine dependence.
1d
How the US Prepares Its Embassies for Potential Attacks
In addition to securing physical structures, the Diplomatic Security Service runs simulations of protests in a model city in Virginia.
1d
Google and Amazon (and Microsoft) are now in the oil business
submitted by /u/YourEmptyWallet [link] [comments]
1d
Impossible Foods is teasing a major announcement coming next week, and it's likely to be a plant-based pork sausage
submitted by /u/mvea [link] [comments]
1d
How Long is a Day on Venus? The Answer Keeps Changing
Researchers have spent decades trying to pin down exactly how long a day on Venus lasts. Finding the answer cuts to the core of fundamental mysteries about the planet.
1d
Make your own concrete flower pots
It's a simple design, but quite effective. (Jeremy S. Cook/) If you've got access to a 3D printer , some concrete, and a few days to let it dry, you won't have to buy flower pots ever again. With a 3D-printed mold, you can create custom vessels that are exactly the size and shape your plants need. Once you have the process down, you'll be able to cast multiple containers and even design unique ho
1d
Breakthrough study on molecular interactions could improve development of new medicines
A first-of-its-kind study on molecular interactions by biomedical engineers will make it easier and more efficient for scientists to develop new medicines and other therapies for diseases such as cancer, HIV, and autoimmune diseases.
1d
Air pollution can worsen bone health
A new study with over 3,700 people in India associates air pollution with a higher risk to develop osteoporosis.
1d
An Unexpected Gold Rush in Small-Town Maine
In the dark of the night, a group of fishermen huddles around a net. They're gathered at a riverbank in Ellsworth, Maine, collecting one of the most lucrative seafood in the world: elvers, or baby glass eels. A 5-gallon bucket brimming with these translucent creatures is worth $32,500—higher than prices for gold . "It's like Christmas!" exclaims Rick Sibley, one of the fishermen. "I can't wait to
1d
Brassica crops best for crop rotation and soil health in potato production systems
Crop rotation is vital to any crop production system. Rotating crops maintains crop productivity and soil health by replenishing organic matter, nutrients, soil structure, and other properties while also improving water management and reducing erosion. Rotating crops also reduces the buildup of soilborne pathogens and diseases.
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A massive clean-up starts to heal China's polluted waters
Nature, Published online: 03 January 2020; doi:10.1038/d41586-019-03966-7 A far-reaching effort to restore lakes and rivers to health finds success in some areas.
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Addictive Behavior Control Circuit Discovered in Rat Brains
Some rats showed a decrease in addictive tendencies when researchers activated the pathway, while the behavior of others became more addictive when the pathway was inhibited.
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Hearing develops in tandem with form and function
New research reveals a key insight into the development of hair bundles, the intricately complex assemblies in the inner ear responsible for hearing. Researchers found that stereocilia, roughly 100 of which are assembled into a hair bundle, widened simultaneously with the onset of mechanotransduction. The stereocilia only elongated to their mature lengths after transduction had been established.
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Keep exercising: New study finds it's good for your brain's gray matter
A study provides new evidence of an association between cardiorespiratory fitness and brain health, particularly in gray matter and total brain volume — regions of the brain involved with cognitive decline and aging.
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Researchers learn more about teen-age T.Rex
A team studied two mid-sized tyrannosaur skeletons and concluded they were in fact teenage T.Rex and not a new pygmy species. They also studied the interior of the leg bones to determine age and how the dinosaurs grew and matured.
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Delivering TB vaccine intravenously dramatically improves potency
Worldwide, more people die from tuberculosis than any other infectious disease, even though the vast majority were vaccinated. The vaccine just isn't that reliable. But a new study finds that simply changing the way the vaccine is administered could dramatically boost its protective power.
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Spectroscopy: A fine sense for molecules
Scientists have developed a unique laser technology for the analysis of the molecular composition of biological samples. It is capable of detecting minimal variations in the chemical make up of organic systems.
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Global extent of river ice loss as Earth warms
A new study found that annual river ice cover will decline by about six days for every one degree Celsius increase in global temperatures. This decline will have economic and environmental consequences.
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How bacteria control their cell cycle
Researchers have demonstrated how bacteria coordinate cell division with the replication of their genetic material. In an interdisciplinary study they explain why the current concept of the bacterial cell cycle has to be rewritten.
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Possible dementia vaccine closer after mice studies
A vaccine to ward off dementia may proceed to clinical trials after successful animal testing. The research is looking to develop effective immunotherapy via a dual vaccine to remove 'brain plaque' and tau protein aggregates linked to Alzheimer's disease. It is showing success in begenic mice models, supports progression to human trials in years to come.
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Crop management study recommends 3-year rotations for potato production systems
Building and maintaining soil health is essential to agricultural sustainability, long-term productivity, and economic viability. Soil health is defined as the continued capacity of soil to function as a vital living system that supports biological productivity, to maintain environmental quality, and to promote plant, animal, and human health.
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Scientists find evidence that Venus has active volcanoes
New research led by Universities Space Research Association (USRA) and published today in Science Advances shows that lava flows on Venus may be only a few years old, suggesting that Venus could be volcanically active today—making it the only planet in our solar system, other than Earth, with recent eruptions.
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The case of the elusive Majorana: The so-called 'angel particle' is still a mystery
A 2017 report of the discovery of a particular kind of Majorana fermion—the chiral Majorana fermion, referred to as the "angel particle"—is likely a false alarm, according to new research. Majorana fermions are enigmatic particles that act as their own antiparticle and were first hypothesized to exist in 1937. They are of immense interest to physicists because their unique properties could allow t
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Tests begin on bones that may be Revolutionary War soldiers
A university laboratory began tests Friday on skeletal remains found beneath an 18th century home in the hopes of identifying the three people believed to be soldiers killed during the Revolutionary War.
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Here's what we really know about CBD's benefits
Assertions about the benefits of CBD often go far beyond what science has shown, according to one expert. Celebrated for its purported therapeutic effects and legal when derived from hemp—a form of the cannabis plant —CBD is in shampoos, hand lotions, skin creams, and even dog treats. Far-reaching medical claims tout its success at treating various conditions such as anxiety , acne, insomnia, add
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Astronomers Carefully Watching Betelgeuse Star, Wondering If It's Nearing Explosion
The star Betelgeuse has been dimming rapidly in recent weeks, leading to speculation that it may soon explode. If it did, that event would be a sight to behold.
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Betrayed by bile: Bile acids help norovirus sneak into cells
Human noroviruses, the leading viral cause of foodborne illness and acute diarrhea around the world, infect cells of the small intestine by piggybacking on a normal cellular process called endocytosis that cells use to acquire materials from their environment.
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Findings strengthen link between vitamin E acetate and vaping-associated lung injuries
New research strengthens prior findings on the link between vitamin E acetate and EVALI (E-cigarette or vaping product use-associated lung injury).
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Long-dormant disease becomes most dominant foliar disease in New York onion crops
Until recently, Stemphylium leaf blight has been considered a minor foliar disease as it has not done much damage in New York since the early 1990s. However, onion growers in New York have recently seen an increase in the dieback of their crops, and scientists were surprised to discover that SLB was the cause.
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North Atlantic Current may cease temporarily in the next century
The North Atlantic Current transports warm water from the Gulf of Mexico towards Europe, providing much of north-western Europe with a relatively mild climate. However, scientists suspect that meltwater from Greenland and excessive rainfall could interfere with this ocean current. Simulations showed that there is a 15 percent likelihood that there will be a temporary change in the current in the n
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Diet has rapid effects on sperm quality
Sperm are influenced by diet, and the effects arise rapidly. This is the conclusion of a new study in which healthy young men were fed a diet rich in sugar. The study gives new insight into the function of sperm, and may in the long term contribute to new diagnostic methods to measure sperm quality.
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Venture capitalist Fred Wilson made an ominous prediction that climate change will be this century's world war
submitted by /u/mvea [link] [comments]
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Samsung's 'artificial human' project: Neon, a realistic CGI human that users can interact with. It could be used for entertainment purposes or by businesses to create digital receptionists, customer service, and so on.
submitted by /u/mvea [link] [comments]
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Oil & Petrochemical Companies Want YOU To Pay To Protect Them From Climate Change
submitted by /u/ngt_ [link] [comments]
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