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'Thousands' of coronavirus cases expected in UK
Medical officer says infections will rise rapidly but defends government policy
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A coronavirus vaccine will take at least 18 months—if it works at all
A fast-track vaccine will be tried on people soon but it uses an unproven technology.
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A Disease Tracker Backed by Gates and Zuckerberg Tackles Covid-19 in Cambodia
The two tech titans funded an effort to bring metagenomic sequencing and software to poor countries. Now, it's helping trace the spread of the new coronavirus.
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Airlines slash flights as coronavirus hits travel demand
Qantas warns slump will be 'survival of the fittest' as American, Delta and United lower forecasts
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Amid Coronavirus Fears, Startups Rethink the Virtual Conference
As more gatherings get shut down due to Covid-19, a new group of companies are trying to re-create the experience online. Hotel cocktail not included.
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As Covid-19 Fears Mount, a Face Mask Shortage Imperils Research
As cases of Covid-19 continue to bleed supplies of N95 respirators dry, infectious disease researchers are scrambling to amass the safety equipment that keeps them safe during high-risk work — a process further jeopardized by panicked purchasing of the masks by members of the general public.
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As the Coronavirus Rages, Airlines Fly Near-Empty "Ghost Flights"
Ghost Flights A number of airlines are being forced to operate near-empty "ghost flights" after the coronavirus outbreak caused sweeping cancellations and demand for airfare to plummet across the globe. "Passenger demand for air travel has dramatically fallen due to COVID-19 and in some instances we are being forced to fly almost empty planes or lose our valuable slots," CEO of Virgin Atlantic Sh
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Bacteria suit up with virus armor [Commentaries]
Particularly with the recent outbreak of coronavirus disease 2019 (COVID-19), viruses have a bad reputation these days. However, it is important to note that viruses come in many types and can infect not only humans but almost all life forms, and their infections are not always detrimental to the host….
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Bank investors confront a new fear: oil company defaults
'Unmitigated selling' of small lenders with energy exposure and double-digit falls for big groups
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Bank of England must issue firm instructions to soften the coronavirus fallout
It's nice of a few high street banks to offer repayment holidays but it's a piecemeal approach. Threadneedle Street must step up The Italian view of mortgages in the age of the coronavirus is big, bold and serious: payments can be suspended , says the government in Rome. So what about the UK? Where are our equivalent emergency measures, should they be needed? Well, there was a flurry of announcem
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Begræns coronasmitten: Stå op på morgenmøderne
Lægerne bør stå op på morgenkonferencen og holde god afstand, siger koncernchef i Region Midtjylland.
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Can Political Reporters Handle the Covid-19 Disinformation Machine?
If the press is ever going to figure out how to report on the mendacity of this administration, now's the time.
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Caxton chief calls for 'overwhelming' coronavirus response
Hedge fund head Andrew Law says policymakers must take stronger action to avoid panic
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China Is Using a Mr. Bean Impersonator to Spread Virus Propaganda
An extraordinary scoop by Sky News : the Chinese government is using a professional Mr. Bean impersonator to spread propaganda about its response to the deadly, COVID-19-causing coronavirus SARS-CoV-2. Sky reports that the impersonator, a British man named Nigel Dixon, was trapped in Wuhan by the outbreak. Now, for some reason, he's appeared in a video by the state-run Xinhua News Agency, to prai
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Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection [Immunology and Inflammation]
Chronic infection provokes alterations in inflammatory and suppressive pathways that potentially affect the function and integrity of multiple tissues, impacting both ongoing immune control and restorative immune therapies. Here we demonstrate that chronic lymphocytic choriomeningitis virus infection rapidly triggers severe thymic depletion, mediated by CD8 T cell-intrinsic type I interferon…
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College Class Cancellations Skyrocket Amid Coronavirus Concerns
Dozens of schools across 11 states have announced emergency policies to help curb the spread of COVID-19.
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Comprehensive testing is key to containing virus
Diagnosing Covid-19 is a vital first step to combating its global spread
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Coronasmittet var til fredagsbar på medicinstudiet
En coronasmittet var i fredags til fredagsbar på Panum Instituttet i København. Alle, der var til stede, bør blive hjemme i 14 dage, opfordrer Styrelsen for Patientsikkerhed.
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Coronavirus and climate change are obvious risks we ignore. Forget black swans. We're getting run over by two gray rhinos: coronavirus and climate change. A gray rhino is a metaphor coined by risk expert Michele Wucker to describe "highly obvious, highly probable, but still neglected" dangers.
submitted by /u/ngt_ [link] [comments]
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Coronavirus and debt: a toxic mix
The combined supply and demand shock could not have come at a worse time
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Coronavirus causes collapse in UK business confidence
Survey finds one in five directors says outbreak poses severe threat
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Coronavirus exposes disparities in US-China healthcare
People moving abroad may reconsider their target country in light of how it deals with outbreak
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Coronavirus Fears Spark a Run on Nintendo's Ring Fit Adventure
The home exercise videogame retails for $80, but increased demand and a manufacturing crunch have sent it skyrocketing.
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Coronavirus Hot Zone: The View from the U.S. Epicenter
Scientific American contributing editor W. Wayt Gibbs reports from the U.S. epicenter of the coronavirus outbreak: Kirkland, Wash. In this first installment of an ongoing series, he looks at why… — Read more on ScientificAmerican.com
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Coronavirus Is Very Different From the Spanish Flu of 1918. Here's How.
The fear is similar, but the medical reality is not.
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Coronavirus Live Updates: Italy Is Locked Down; Global Deaths Top 4,000
Nationwide restrictions on travel and public gatherings began in Italy on Tuesday. China's leader, Xi Jinping, visited Wuhan, where the outbreak began.
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Coronavirus live updates: Italy under lockdown as WHO says threat of pandemic 'very real'
UK and US had worst days trading since 2008 GFC; Global cases near 110,000; Grand Princess passengers disembark. Follow the latest news. Cruise ship carrying at least 21 with coronavirus docks in California US pledges more testing as Trump hints at aid for workers Quarantined US congressman flew with Trump on Air Force One Global stock markets post biggest falls since 2008 financial crisis Italia
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Coronavirus map: all the confirmed US cases
As of Tuesday morning, the US has more than 500 confirmed cases across 35 states Coronavirus: live updates Coronavirus symptoms: what are they and should I see a doctor? The number of cases of Covid-19 (coronavirus) continues to grow in the US. Mike Pence, the US vice-president, is overseeing the US response to coronavirus. So far, 80% of patients experience a mild form of the illness, which can
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Coronavirus puts electric carmakers on alert over lithium supplies
Battery maker Livent says industry is looking to diversify away from China
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Coronavirus risks the return of currency wars
US monetary easing should be done with Japan and the eurozone and not to them
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Coronavirus sufferers symptom-free for five days on average – study
Findings suggest the 14-day quarantine period used around world strikes a good balance Coronavirus – live updates People infected with coronavirus are symptom-free for an average of five days, according to a study that reinforces the need for strict quarantine measures. The analysis found that 5.1 days was the median length of time before people started showing signs of illness, although there wa
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Coronavirus symptoms: what are they and should I see a doctor?
What is Covid-19, how does it spread, what are the symptoms, and at what point should you call a doctor? Find all our coronavirus coverage here How to protect yourself from infection Coronavirus – live news updates It is caused by a member of the coronavirus family that has never been encountered before. Like other coronaviruses, it has come from animals. Continue reading…
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Coronavirus: China's risky plan to revive the economy
Beijing is targeting a second-quarter rebound but the crisis has exposed the limitations of the system under Xi Jinping
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Coronavirus: Universities are shifting classes online, but it's not as easy as it sounds
In response to the novel coronavirus, many South Korean universities have moved their teaching online. Students are still provided with the required number of class hours but without face-to-face contact with teachers.
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COVID-19 symptoms pop up 5 days after exposure
The average time from exposure to onset of COVID-19 symptoms is 5.1 days, researchers report. This suggests that the 14-day quarantine period the US Centers for Disease Control and Prevention are using for individuals with likely exposure to SARS-CoV-2, the new coronavirus that causes the respiratory illness COVID-19, is a reasonable amount of time to monitor individuals for development of the di
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Covid-19: New Zealand government accused of 'flat-footed' response
Opposition claims not enough is being done to stimulate economy, despite Jacinda Ardern saying nation is in robust position to fight coronavirus The New Zealand government's economic response to coronavirus has been criticised as "startlingly flat-footed" and a symptom of "complacency". On Tuesday, the New Zealand stock market dropped 4.85% in the first half hour of trading, prompting opposition
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COVID-19: time for WHO to reconsider its stance towards Taiwan
Nature, Published online: 10 March 2020; doi:10.1038/d41586-020-00693-2
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Critics take aim at 'failure' of pandemic bond
Instruments issued by World Bank have yet to pay out to combat the coronavirus
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Despite Coronavirus, Washington Isn't Worried About Its Primary
The state conducts its elections almost entirely by mail. The rest of the country should pay attention.
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Disruption of cellular proteostasis by H1N1 influenza A virus causes {alpha}-synuclein aggregation [Medical Sciences]
Neurodegenerative diseases feature specific misfolded or misassembled proteins associated with neurotoxicity. The precise mechanisms by which protein aggregates first arise in the majority of sporadic cases have remained unclear. Likely, a first critical mass of misfolded proteins starts a vicious cycle of a prion-like expansion. We hypothesize that viruses, having…
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Does closing schools slow the spread of coronavirus? Past outbreaks provide clues
A researcher who forecasts epidemic spread argues that proactive closures, though disruptive, could help
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EU eyes coronavirus measures for business
Ursula von der Leyen promises exceptional measures to tackle 'vast impact' of crisis
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EU vows to use all tools available to battle coronavirus impact
Some countries, including Germany, are sceptical about budgetary loosening
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F.D.A. Halts Overseas Inspections of Drugs and Devices, Citing Coronavirus
The agency said the spread of the virus globally prompted its decision. It had already pulled back from China, but this move will also affect India, a major generics manufacturer.
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Fighting coronavirus's economic effects will take more than interest rate cuts | Barry Eichengreen
Political leaders and central banks must listen to experts' advice on containing the outbreak Coronavirus – latest updates Last week, G7 finance ministers and central bank governors vowed to use "all appropriate policy tools" to contain the economic threat posed by the coronavirus. The question left unanswered is what is appropriate and what will work. The immediate response took the form of cent
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Finding 'patient zero': The challenges of tracing the origins of coronavirus
Every country that confirms a local case of COVID-19 – and there are more than 70 such countries now – faces the daunting task of tracking down its initial patient. This is an important means to safeguard the broader population because locating everyone that this "patient zero" has come into contact with can help curb further transmission. But the people contracting this particular coronavirus do
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Forskning: Coronavirus förväntas bryta ut efter fem dagar
En ny studie pekar på en förväntad inkubationstid för det nya coronaviruset på ungefär fem dagar. Studien ger ett starkare underlag för hur samhällen bör agera i fråga om coronaviruset.
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Gates Foundation Will Make Home Coronavirus Testing Kits Available
Public Domain: NIAID Rocky Mountain Laboratories (RML), U.S. NIH One of the problems with tackling the coronavirus epidemic is that in the United States at least, a severe shortage of test kits has prevented doctors across the nation from measuring which individuals have coronavirus and which do not. As a result, the official US tally of roughly 700 cases is believed to be a significant undercoun
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Gates Foundation, Wellcome set up coronavirus drug fund
Research foundations join forces with Mastercard-backed charity to develop treatments
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Get rich or die trying: the people trying to make money from coronavirus | Arwa Mahdawi
While most of us are attempting to stay calm and protect ourselves from the disease, others are keen to make a quick buck from the panic The coronavirus crisis has revealed five distinct personality types. First, the paper panickers (PPs): the people stockpiling toilet paper . While most PPs are well aware that loo roll is inedible and does not wipe away the virus, they do not seem to care; they a
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Good News: Experts Say There's Still No Evidence You Can Catch Coronavirus From Pets
One less thing to worry about.
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Hopes rise over experimental drug's effectiveness against coronavirus
Many see remdesivir as one of few drugs that has reasonable prospect of helping patients A US biotech firm has ramped up production of an experimental drug that has become a focal point for hopes of an effective treatment for coronavirus. The first clinical trial of the antiviral medicine remdesivir in Covid-19 patients is due to report its findings next month according to Gilead Sciences, which
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How a virus forms its symmetric shells
Viruses have been well studied, but many mysteries linger. One such mystery is how a spherical virus circumvents energy barriers to form symmetric shells. A research team has made progress is solving this mystery. The team reports that an interplay of energies at the molecular level makes the formation of a shell possible.
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How an Australian researcher ended up in the spotlight at a White House coronavirus briefing
Preprint led by epidemiologist Craig Dalton becomes basis for major education effort
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How countries around the world are battling coronavirus
Measures taken differ markedly with some draconian and others falling short
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How do we adapt if COVID moves teaching online?
How can K-12 school leaders prepare for weeks or months of teaching online? "…this is not like an extended snow day. Some of the teachers are going to get sick." The COVID-19 virus has started to close schools and college campuses in the United States. Public health officials predict that coronavirus cases will only continue to rise. Here, Ryan Baker, director of the Penn Center for Learning Anal
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How the Coronavirus Is Hampering Science
Research meetings are being canceled left and right over epidemic fears, slowing the work of scientists—especially those who are early in their career — Read more on ScientificAmerican.com
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In the Coronavirus, Historians See Echoes of Past Pandemics
When a mysterious new coronavirus started to spread out of Wuhan, China, last year, fear began to grow that it would turn into a new global pandemic. Now, months after reports of an outbreak began, the SARS-CoV-2 coronavirus has infected nearly 100,000 and killed just over 3,300 people around the world — a rapid spread in which some historians see parallels to deadly historical diseases. Graham M
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Informa to postpone or scrap events worth £450m over virus
Shares drop by almost a quarter in three weeks and chief warns of revenue hit
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Italy boosts aid package as Europe battles outbreak
Measures designed to mitigate impact of severe movement restrictions across country
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Italy Imposes Nationwide Travel Restrictions as Death Toll Soars
In a televised address today, Italian prime minister Giuseppe Conte announced that coronavirus quarantine measures would be extended nationwide with travel only permitted for work or family emergencies, as the BBC reports . In the address, Conte said that the best thing was for citizens to stay at home, in large part to protect the most fragile members of society. Outside of China, Italy now has
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Italy on full lockdown to slow the spread of coronavirus
The Italian government has put the entire population of 60 million people on lockdown. People must limit travel except for work or medical reasons or risk prison or a fine
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Italy Shut Down. Which Country Will Be Next?
"We are out of time," Italian Prime Minister Giuseppe Conte said yesterday evening. "We have to stay home." With those words , he announced the most stringent restrictions on freedom of movement imposed in Europe since the Second World War: 60 million Italians can now move around only for pressing reasons of work, health, or other extenuating necessity—and then only with written permission. Conte
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Johnson's handling of virus crisis put in spotlight
PM says draconian action is at best ineffective, at worst counter-productive
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Keep up with the latest coronavirus research
Nature, Published online: 10 March 2020; doi:10.1038/d41586-020-00694-1
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Knowing more about a virus threat may not satisfy you
People who rate themselves as highly knowledgeable about a new infectious disease threat could also be more likely to believe they don't know enough, a new study suggests. In the case of this study, the infectious disease threat was the Zika virus. But the authors of the new study say the results could apply to the recent novel coronavirus (COVID-19) outbreak.
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Labs rush to study coronavirus in transgenic animals — some are in short supply
Nature, Published online: 09 March 2020; doi:10.1038/d41586-020-00698-x Mice originally bred for SARS research are in high demand.
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Latest Research Says The Average Incubation Time For The New Coronavirus Is 5.1 Days
Some good news for once.
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Ledende overlæge om coronavirussen: Det er stilhed før stormen
Alt er stadig normalt på organkirurgisk afdeling på Kolding Sygehus, men det kan hurtigt ændre sig, siger ledende overlæge.
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Message Received: Italians Are Staying Home
Italy Italian Lockdown
Italy is under Europe's first nationwide restriction on movement. 'Surreal,' said one citizen.
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Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses [Biophysics and Computational Biology]
The 1918 influenza A virus (IAV) caused the most severe flu pandemic in recorded human history. Nonstructural protein 1 (NS1) is an important virulence factor of the 1918 IAV. NS1 antagonizes host defense mechanisms through interactions with multiple host factors. One pathway by which NS1 increases virulence is through the…
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My Coronavirus Comment For the Day
Randall Munroe nails our current situation:
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New study on COVID-19 estimates 5.1 days for incubation period
An analysis of publicly available data on infections from the new coronavirus, SARS-CoV-2, that causes the respiratory illness COVID-19 yielded an estimate of 5.1 days for the median disease incubation period, according to a new study.
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New York sends in National Guard to contain coronavirus
Troops to help check spread of virus in hard-hit suburban community of New Rochelle
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No elevated risk of coronavirus in pregnancy, experts say
No evidence virus passes to foetus during pregnancy, according to latest research Coronavirus – latest updates Pregnant women do not appear to be more susceptible to severe Covid-19 symptoms and there is no evidence that the virus can pass to a baby during pregnancy, according to new guidance . The guidelines, issued by the Royal College of Obstetricians and Gynaecologists, Royal College of Midwi
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Oil and gas companies invest in legislators that vote against the environment [Environmental Sciences]
Do campaign contributions from oil and gas companies influence legislators to vote against the environment, or do these companies invest in legislators that have a proven antienvironmental voting record? Using 28 y of campaign contribution data, we find that evidence consistently supports the investment hypothesis: The more a given member…
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Oil and stock markets bounce after historic rout
Investors bet on stimulus as China signals outbreak has peaked with Xi Wuhan visit
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Oil price war puts $110bn of US energy bonds on the brink
Debt issued by US producers plummets in price, mirroring crude
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Oil price war will hit virus fight, says energy chief
Russia and Saudi branded 'irresponsible' for timing of spat amid global crisis
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OVERBLIK: Disse arrangementer på sundhedsområdet bliver aflyst som følge af corona
Få overblikket over, hvilke møder eller arrangementer der bliver aflyst eller udskudt som følge af coronavirussen. Listen opdateres løbende.
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Remote teaching becomes vital during virus outbreak
Universities and business schools are facing unprecedented challenges across the world
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Scientists: This Is How Long It Takes to Show Coronavirus Symptoms
Part of the challenge during the ongoing COVID-19 outbreak has been that scientists and public health officials are still struggling to understand what makes the coronavirus tick. Now, though, researchers are starting to examine the growing dataset of cases — and fill in the gaps about how the SARS-CoV-2 virus moves through individual bodies and society at large. In a new paper published in the A
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Secret U.S. Intel Report: America Unprepared for Global Pandemic
A secret report by the Director of National Intelligence says that the United States is starkly unprepared for a global pandemic — and the White House is blocking its release. At least, that's according to two senior government officials who blabbed to Time about the report, which was scheduled to be released early February, according to the magazine. But, says Time , plans to release it were scr
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Should I shave my beard, can I get COVID-19 twice, and every other question you might have about the coronavirus
Our answers to some of the most common questions we've been getting about COVID-19. (Pexels/) Follow all of PopSci's COVID-19 coverage here , including travel advice , pregnancy concerns , and the latest findings on the virus itself . Since the novel coronavirus began spreading throughout China in January, it has reached 104 additional countries and infected 109,577 people globally. So far, 3,809
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Spain closes schools in Madrid and hard-hit regions
Shift in stance after earlier reluctance to impose measures to stem coronavirus
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Spain steps up efforts to avoid 'Italian scenario'
Madrid under fire for not acting faster to contain spread of outbreak
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Statsministeren: COVID-19 kan medføre mangel på intensivpladser
Meget syge og behandlingskrævende patienter kan ende med at ligge på hospitalernes gange, hvis danskerne ikke gør alt hvad de kan for at afbøde kraftig epidemi.
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Storms and Covid-19 worries hurt high street retailers
Stores and restaurants suffer most but online sales boost overall spending
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Sundhedsstyrelsen advarer: Corona vil betyde lavere faglig standard
Hvis det ikke lykkes at begrænse omfanget af corona-smitten, kan respirator-kapaciteten til sårbare patienter blive en reel udfordring, når sygdommen topper, siger Søren Brostrøm.
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Superdatorer sätts in mot coronavirus
Med hjälp av Summit, världens mest kraftfulla superdator, har forskare vid Oak Ridge National Laboratory i USA på kort tid lyckats identifiera 77 läkemedelsmolekyler som skulle kunna ha effekt på coronaviruset SARS-CoV-2.
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Særlig regel tvinger selskaber til spøgelsesflyvninger under corona-epidemi
PLUS. Både SAS og Norwegian ønsker at slippe for at overholde den såkaldte 80/20 regel om, at størstedelen af flyvningerne skal gennemføres, selv med halvtomme fly. Minister bakker op.
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Tech groups link with NHS against false virus advice
Google, Twitter and Facebook users will be directed to verified official guidance
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The Atlantic Politics Daily: Running for President During an Epidemic
It's Tuesday, March 10. Ordered here by the number of delegates up for grabs: Michigan, Washington State, Missouri, Mississippi, Idaho, and North Dakota vote (in ND's case, by caucus) today. In the rest of today's newsletter: Out with the handshakes, in with the hand sanitizer—Joe Biden and Bernie Sanders have both canceled rallies planned for tonight. Plus: From "Never Trump" to "Why not Trump."
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The Coronavirus Campaign
Updated on March 10 at 4:58 p.m. ET. T he first thing to go was the rope line. Until this weekend, former Vice President Joe Biden would end his scripted rallies with a far more intimate tradition of campaign politics—by greeting his supporters personally, and physically. He'd press the flesh, high-fiving, shaking hands, leaning in close for photos with dozens, if not hundreds, of people crowded
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The coronavirus may force American schools to teach online. Are they ready?
The COVID-19 virus has started to close schools and college campuses in the United States.
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The Dangerous Delays in U.S. Coronavirus Testing Haven't Stopped
Nearly two weeks after the new coronavirus was first found to be spreading among Americans, the United States remains dangerously limited in its capacity to test people for the illness, an ongoing investigation from The Atlantic has found. After surveying local data from across the country, we can only verify that 4,384 people have been tested for the coronavirus nationwide, as of today at 4 p.m.
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The Voices of the Loneliness Epidemic
In January 2018, Theresa May, then the prime minister of the United Kingdom, made an unusual appointment: Tracey Crouch would serve as the world's first minister for loneliness. The position, May said, would address the fact that, for an estimated 9 million U.K. citizens, "loneliness is the sad reality of modern life." At the time, Alice Aedy , a British filmmaker in her 20s, was disconcerted by
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There Are No Libertarians in an Epidemic
"America vs. Socialism" was the theme of the Conservative Political Action Conference last month, though as fights go this one was pretty one-sided. An anti-socialist message thrummed through the halls while the crowds celebrated free-market capitalism over $4 cups of coffee and $20 chicken-salad sandwiches wrapped in cellophane. As the panelists likened socialism to a disease, an actual disease,
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These self-appointed coronavirus experts really need to pipe down | Eleanor Margolis
Donald Trump, Nigel Farage and the Twitterati should leave the public announcements to the epidemiologists I'm no financial expert, but – if you ask me – why not withdraw every last penny from your bank account, head to your nearest casino and put it all on red? You could literally double your money. Sure, something else could happen entirely. But all investments are risky, right? And, like I said
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This, Not Hand Sanitizer, Will Save Us from the COVID-19 Coronavirus
In the global health war against the COVID-19 coronavirus, there are two measures we know of that effectively prevent the spread of the outbreak while the world waits on a vaccine: Quarantine/social isolation, and cleaning your hands. But what's the best — if not only surefire way — to get that right? Washing them with soap and water. Not hand sanitizer. Not just water. It's soap and water. This
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Trump summons top bankers for coronavirus meeting
Global lenders race to respond to outbreak and risks it poses to business and the economy
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UK lenders provide relief to customers hit by coronavirus
RBS to allow personal borrowers to defer mortgage and loan repayments
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UK shoppers rush to buy frozen food and freezers amid coronavirus outbreak
Freezer sales at AO.com and John Lewis soar as Iceland reports surge in frozen food purchases Coronavirus – latest updates Sales of both freezers and frozen food have surged in the UK amid panic buying by Britons worried about the spread of coronavirus. The online appliance retailer AO.com said freezer sales jumped more than 200% last week as worried shoppers sought to increase their ability to s
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UN chief says drop in emissions from virus will not solve climate crisis
UN Secretary General Antonio Guterres warned Tuesday that while the global outbreak of coronavirus may have caused a temporary drop in emissions that cause global warming, it would not end the problem and might even divert attention from the fight.
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Under coronavirus lockdown, Italy is finding a fragile sense of solidarity | Jamie Mackay
In Florence, where I live, the squares are empty. Despite political infighting, Italy is showing how to quell the panic On Monday evening the Italian prime minister, Giuseppe Conte, announced that the whole of Italy was to be designated a "protected zone", and placed under lockdown as cases of Covid-19 in the country rose to 9,172, with 463 deaths. For the next month, until 3 April, 60 million Ita
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Verdens mest kraftfulde supercomputer bekæmper corona
Verdens mest kraftfulde supercomputer hjælper med at begrænse udbruddet af Covid-19. Forskere har fået hasteadgang til at udføre simuleringer.
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Virus testing to rise 500% as UK boosts preparations
Authorities to process 10,000 tests daily as health minister Nadine Dorries diagnosed with disease
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We don't know why so few Covid-19 cases have been reported in Africa
Experts still don't know why so few coronavirus cases have been reported in Africa, despite the continent's large population and China being its top trading partner
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'We're a bit shocked': Italians on life under coronavirus lockdown
From Milan to Palermo in Sicily, few people are even venturing out for a coffee in the local bar Coronavirus latest | At a glance Bar Il Sant'Andrea is something of a barometer for the liveliness of Orvieto, a hilltop town of about 4,000 people in Italy's central Umbria region. On a typical morning, it would be buzzing with customers having coffee, chatting or reading the newspapers. On Tuesday,
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What Could Warming Mean for Pathogens Like Coronavirus?
submitted by /u/speakhyroglyphically [link] [comments]
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White House pushes tax cut to aid virus-hit economy
Donald Trump fails to make stimulus announcement as promised as Democrats push back on plan
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Who's profiting most from the coronavirus outbreak?
The novel coronavirus has so far infected more than 110,000 people and killed nearly 4,000. "Stay-at-home" companies — like Netflix and Amazon — seem to be uniquely poised to weather the outbreak. Media companies also appear to be profiting from surges in coronavirus-related traffic. The novel coronavirus, which causes the disease COVID-19, has infected 110,000 people and killed 4,000 across six
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Why Deaths from Coronavirus Are So High in Italy
Italy Italian Lockdown
The nation now has the highest number of deaths from COVID-19 outside of mainland China — Read more on ScientificAmerican.com
4h
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Why investors should brace for aftershocks
Good reasons to be wary remain despite bounce in equity markets following day of mayhem
10h
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Why the coronavirus outbreak is terrible news for climate change
It'll sap funding and political will—but actually, it should.
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With Italy in lockdown, fear over coronavirus is natural but we must not be alarmist | Gaby Hinsliff
It's hard not to worry, but we have to hope the epidemiologists are giving the UK government the right advice In a epidemic, nothing spreads as fast as fear. There are only so many pictures of Italy's deserted cafes and empty streets that the average Briton can look at without beginning to wonder why we're not on lockdown too. Social media only feeds the hysteria, spawning endless scary-looking g
7h
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Xi Jinping visits Wuhan as coronavirus cases plummet
President makes first trip to city as Beijing says new infections at lowest level since January
18h
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You Have A Fever And A Dry Cough. Now What?
Whether your mild or moderate symptoms mean you have a cold, the flu, or COVID-19 doesn't change the medical advice right now. Stay home, rest, and call or email your doctor if symptoms worsen. (Image credit: Guido Mieth/Getty Images)
2h
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A Very Unwelcome Wedding Guest
Steven Zarnfaller's elderly cousin couldn't risk attending his wedding. Last week, Zarnfaller got a call from the 78-year-old, who has been like a mother to him. Given the news about the coronavirus, she told him, it was too dangerous for her to fly from New York to Oakland, California, for his April 5 ceremony. Since COVID-19, the disease caused by the coronavirus, appears to be especially deadl
5h
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Adorable Self-Driving Vans Are Disinfecting Roads in China
Driverless in Seattle Driverless delivery vehicle startup Neolix is raking in new customers as cities in China are under full lockdown due to the coronavirus outbreak. The company has gotten orders for 200 tiny robotic vehicles, up from 125 since last May, according to Bloomberg , including commerce juggernauts Alibaba and JD.com. The company's small autonomous delivery vehicles have proven extre
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Business has probably fallen 80%, says Rome café owner
Eternal City falls silent as draconian coronavirus restrictions hobble Italy
4h
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Chinese companies get back to work — but with stricter rules
Coronavirus measures such as anti-crowding restrictions in elevators offer a road map for global peers
11h
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Give People Money Immediately
Financial markets are in meltdown mode as the coronavirus courses rapidly and all too undetectably throughout the world. But there is a simple thing the U.S. government can do right now, which would both slow the viral spread and limit the economic harm. Give people and companies money. Perhaps that intervention strikes you as a non sequitur. Dollar bills aren't medicine, COVID-19 doesn't discrim
8h
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Looking for love? Wash your hands first, say dating apps
How dating apps are adapting to love in the time of coronavirus Dating apps are adapting to love in the time of coronavirus, warning their users of the elevated risks of going on dates while trying to ensure they do not switch off entirely when the time comes to self-isolate. OKCupid, which prides itself on its data-led approach to dating, asking users to fill in detailed questionnaires and match
7h
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Passengers Fought Over Rotten Food on Quarantined Cruise Ship
The cruise ship industry is going through a bit of a PR crisis, courtesy of the coronavirus outbreak. Thousands of passengers have had to be quarantined for weeks on end, trapped inside tight quarters on board a number of ships . Now, it sounds like a number of quarantined passengers have — understandably — caught a bad case of cabin fever (pun intended), with food getting tight while the number
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Studies Estimate Incubation Time, Infectious Period of SARS-CoV-2
It takes a median of five days after infection to get sick, and patients shed the most coronavirus particles early in the illness, according to two new reports.
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Time Scales, Viral and Human
I can tell that the current events are getting a bit overwhelming by the difficulty of writing about other topics here! I'm not specifically on a coronavirus topic today, but rather on what some of the news coverage is saying about our expectations for medical research. One of the things people have noted about my two recent posts on potential therapies is that I have not been too optimistic abou
8h
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Why there are no winners from the oil price plunge
Coronavirus hit to demand will prevent any boost to growth, economists say
19h
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Can Finland's Saimaa seals survive climate change?
This breed of seal is facing extinction but conservationists in Finland are trying to save it.
9min
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Climate change: Carbon-reducing seagrass planted off Welsh coast
The "wonder plant" absorbs carbon dioxide faster than trees and supports wildlife, scientists say.
5h
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Climate change: UK 'can't go climate neutral before 2050'
The UK cannot reach net zero before 2050 unless people stop flying and eating red meat, a report says.
22h
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Climate shifts prompt shrubs and trees to take root in open areas
Wild, treeless landscapes are becoming more wooded as climate change leads to warming temperatures and wetter weather, research suggests.
10h
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Climate variations may impact the base of the food web along the California coast
In a recent study published in Marine Ecology Progress Series, researchers at California Polytechnic State University revealed that in addition to seasonal changes in winds and ocean temperatures, natural climate cycles greatly influenced the base of the food web at the Cal Poly Pier in San Luis Obispo Bay, an embayment located in Central California in the California Current Large Marine Ecosystem
1d
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How awareness about the need for climate change mitigation could be turned into action
Awareness of climate change and its impacts is not enough to move people to action. New research on how people's worldview affects their perceptions and actions could help policymakers and activists reframe the discussion around climate change mitigation.
12h
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Klimaråd: Kontrollører bør tjekke om byggeri overholder krav til energirenovering
Selv om der i årevis har været energikrav, der skal overholdes ved skift af tag, vinduer og døre, har ingen tjekket om de blev overholdt.
12h
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Klimarådets forkærlighed for CO2 lagring vækker undren hos IDA og brintbranchen
Både Brintbranchen og IDA mener, at Klimarådet undervurderer det langsigtede potentiale i power-to-x og at lagring af CO2 er en for kortsigtet løsning. Vi vælger det meste økonomiske, siger Klimarådet
14h
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New carbon membrane generates a hundred times more power
Leiden chemists have created a new ultrathin membrane only one molecule thick. The membrane can produce a hundred times more power from seawater than the best membranes used today. The researchers have published their findings in Nature Nanotechnology.
11h
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New framework factors climate risk into financial valuation
The University of Waterloo has developed a tool to help the capital markets incorporate physical climate change and extreme weather risk into investment decisions.
9h
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New pasture cultivar to tackle effects of climate change
Murdoch University researchers have delivered a new cultivar of French Serradella that is set to increase the sustainability of Wheatbelt crop-pasture rotations and lower the carbon footprint of cropping by as much as 50 percent.
10h
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Planet's largest ecosystems collapse faster than previously forecast
New research has shown that large ecosystems such as rainforests and coral reefs can collapse at a significantly faster rate than previously understood. The findings suggest that ecosystems the size of the Amazon forests could collapse in only 49 years and the Caribbean coral reefs in just 15 years.
7h
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Reply to Santin et al.: Viscoelastic retardant fluids enable treatments to prevent wildfire on landscapes subȷect to routine ignitions [Physical Sciences]
Our recent paper (1) reports the development and pilot-scale validation of viscoelastic carrier fluids for ammonium polyphosphate (APP), the primary retardant used in wildland firefighting, to improve retention on common ignition-prone vegetation to protect through environmental exposure. In response to our paper, Santín et al. (2) state that while our…
7h
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Scientists warn of 'critical gaps' in Australia's climate science capability
Exclusive: Australia needs the expertise to predict changes which have a major impact across the country, a review finds A government-backed review of Australia's climate science capability has identified "critical gaps" in the nation's ability to understand the processes that underpin climate change, with atmospheric modelling lagging other countries. It found Australia was in danger of losing "
7h
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The Hidden Toll of Wildfires
A huge aerial campaign seeks to understand the effects of biomass smoke on human health — Read more on ScientificAmerican.com
11h
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There's no 'deadline' to save the world. Everything we do now has to pass the climate test | Damian Carrington
The climate crisis can't be averted, it's here. And with human suffering now a reality, governments can no longer stand idly by You may have read that there are just eight, or 10, or 12 years to save the world from the climate crisis. There are not. It is already here, gaining strength every day as carbon emissions pour into the atmosphere. It is a slow-motion disaster. Action to avert the worst
10h
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This coral reef is super resilient. Here's the plan to save it
The coral reef ecosystem in the Red Sea's Gulf of Aqaba is strikingly resilient to rising sea temperatures, say researchers. Rapid ocean warming due to climate change is predicted to decimate 70 to 90% of the world's coral reefs by mid-century, cite the researchers in their appeal to UNESCO to declare the Red Sea's 2,500 miles of coral reef as a Marine World Heritage Site. They also recommend add
9h
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Trump's Next Chief of Staff Is Open to Doing More on Climate
While he opposed the Paris climate agreement, Representative Mark Meadows has signaled support for renewables and a possible carbon tax — Read more on ScientificAmerican.com
6h
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Under What Conditions Will Clean Energy Become The Norm?
submitted by /u/Andromedu5 [link] [comments]
13h
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Varmaste vintern i Stockholm på 250 år
Mätningar från observatoriet i Stockholm visar att årets vinter var det varmaste på 250 år.
8h
<><>fakenews
How technology can combat the rising tide of fake science. Neural net technology under development at the University of Arizona will flag science websites with a color code indicating their reliability . A smartphone app version will gamify the process of declaring science articles real or fake
submitted by /u/Wagamaga [link] [comments]
13h
<><>fakenews
Some YouTube science videos are riddled with scams, plagiarism, and misinformation
Upstart video makers have benefited young and old audiences alike. But how do these YouTube science communicators source their facts? (Rachit Tank/Unsplash/) Dan Garisto is a science journalist based in New York. He writes about physics and has been published in outlets including Scientific American , Symmetry , Science News , Hakai , and Nature News . This story originally featured on Undark . S
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<><>fakenews
The Conspiracies Are Coming From Inside the House
F our years ago , when Russia's internet trolls wanted the American electorate to lose confidence in democracy, they had to work hard at it—by recirculating cynical postings from obscure social-media accounts, or by making up their own. The message then was that everything in American society had been rigged: elections, football games, the stock market, primaries, polls, the media, "the system."
12h
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The Lancet HIV: Study suggests a second patient has been cured of HIV
A study of the second HIV patient to undergo successful stem cell transplantation from donors with a HIV-resistant gene, finds that there was no active viral infection in the patient's blood 30 months after they stopped anti-retroviral therapy, according to a case report published in The Lancet HIV journal and presented at CROI (Conference on Retroviruses and Opportunistic Infections).
11h
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Women who were tall and lean in childhood more at risk of endometriosis – study
Study analysed data from more than 170,000 women born in Denmark between 1930 and 1996 Girls who are tall and lean in childhood are more at risk of later developing endometriosis, research has found. Endometriosis is a painful, often debilitating, condition in which tissue similar to that found lining the womb is found elsewhere in the body, such as the bowel or ovaries. When it breaks down and b
23h
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Your coffee and chocolate could increase malaria risk
High demand commodities contribute to deforestation and mosquito proliferation.
8h
*Call of Duty* Will Launch a Free-to-Play, Cross-Platform Game
*Warzone*, whose existence leaked a month ago, was finally announced on the official Activision blog.
13h
'A flawed decision:' What happened when sports scientists tried to correct the scientific record, part 2
Why is it so difficult to correct the scientific record in sports science? In the first installment in this series of guest posts, Matthew Tenan, a data scientist with a PhD in neuroscience, began the story of how he and some colleagues came to scrutinize a paper. In this post, he explains what happened next. … Continue reading
14h
'Star particles' could offer painless treatment for skin diseases
Microscopic particles, called STAR particles, could potentially offer better treatment of skin diseases like psoriasis, warts, and certain kinds of skin cancer. Skin diseases affect half of the world's population, but many treatments are not effective, require frequent injections, or cause significant side effects. In a new study in the journal Nature Medicine , Mark Prausnitz and the researchers
10h
"Healthy Directions" Is a Double Misnomer
Healthy Directions sells dietary supplements without scientific evidence. A better name would be Misdirections that Won't Make You Healthy.
17h
A broad look at plant-environment interactions
Three plant science journals—the American Journal of Botany (AJB), Applications in Plant Sciences (APPS), and the International Journal of Plant Sciences (IJPS)—have joined efforts to provide a broad look at how plants interact with their environment. The journals have published cross-journal special issues featuring research on plant stress, reproduction, and mutualisms (AJB); novel methods a
1d
A cnidarian parasite of salmon (Myxozoa: Henneguya) lacks a mitochondrial genome [Evolution]
Although aerobic respiration is a hallmark of eukaryotes, a few unicellular lineages, growing in hypoxic environments, have secondarily lost this ability. In the absence of oxygen, the mitochondria of these organisms have lost all or parts of their genomes and evolved into mitochondria-related organelles (MROs). There has been debate regarding…
7h
A comparative genomics approach identifies contact-dependent growth inhibition as a virulence determinant [Microbiology]
Emerging evidence suggests the Pseudomonas aeruginosa accessory genome is enriched with uncharacterized virulence genes. Identification and characterization of such genes may reveal novel pathogenic mechanisms used by particularly virulent isolates. Here, we utilized a mouse bacteremia model to quantify the virulence of 100 individual P. aeruginosa bloodstream isolates and performed…
6h
A controlled trial for reproducibility
Nature, Published online: 10 March 2020; doi:10.1038/d41586-020-00672-7 For three years, part of DARPA has funded two teams for each project: one for research and one for reproducibility. The investment is paying off.
12h
A Guide to Real-Time Live-Cell Imaging & Analysis
[no content]
11h
A novel biofuel system for hydrogen production from biomass
A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has presented a new biofuel system that uses lignin found in biomass for the production of hydrogen.
19h
A rare natural phenomenon brings severe drought to Australia. Climate change is making it more common
Weather-wise, 2019 was a crazy way to end a decade. Fires spread through much of southeast Australia, fuelled by dry vegetation from the ongoing drought and fanned by hot, windy fire weather.
9h
Active learning narrows achievement gaps for underrepresented students in undergraduate science, technology, engineering, and math [Psychological and Cognitive Sciences]
We tested the hypothesis that underrepresented students in active-learning classrooms experience narrower achievement gaps than underrepresented students in traditional lecturing classrooms, averaged across all science, technology, engineering, and mathematics (STEM) fields and courses. We conducted a comprehensive search for both published and unpublished studies that compared the performance of
6h
Advances in Immune Cell Profiling
Profiling immune cells can help us understand how they impact cancer prognosis and responsiveness to treatment
5h
Affordable waterproof Bluetooth speakers for the outdoor party season
Splish splash and have a blast. (Jakob Owens via Unsplash/) We have become a culture that demands our music, our way, at all times. Not only do our devices need to stream whatever song we come up with on a whim, we need wireless, portable speakers to blow it out when we do so. And if we want to do all of this in a pool? You'd better believe we will demand that, too. Finding Bluetooth-enabled spea
1h
After 90 years, scientists reveal the structure of benzene. 'Benzene is the fundamental building-block of many opto-electronic materials, which are revolutionizing renewable energy and telecommunications, with implications for future designs of solar cells and next-gen tech'
submitted by /u/dannylenwinn [link] [comments]
13h
AI makes detecting methane leaks less confusing
A system that uses hyperspectral imaging and machine learning could detect the specific wavelength of methane emissions, researchers propose. Though not as prevalent in the atmosphere as carbon dioxide, methane is a far more potent greenhouse gas. Occurring naturally as well as being humanmade, methane is much shorter-lived than CO 2 , but it is fast acting and 20 to 80 times as effective at trap
11h
AI paves the way for automated diabetes kit
'DIY' monitoring systems are one answer to regulatory delays
19h
Alterations in chromatin at antigen receptor loci define lineage progression during B lymphopoiesis [Immunology and Inflammation]
Developing lymphocytes diversify their antigen receptor (AgR) loci by variable (diversity) joining (V[D]J) recombination. Here, using the micrococcal nuclease (MNase)-based chromatin accessibility (MACC) assay with low-cell count input, we profile both small-scale (kilobase) and large-scale (megabase) changes in chromatin accessibility and nucleosome occupancy in primary cells during lymphoid deve
7h
Amazon now selling patented "Just walk out" technology to other retailers (
submitted by /u/amuka [link] [comments]
13h
Amazon offers cashierless tech to rival retailers. "Just Walk Out technology enables shoppers to simply enter a store, grab what they want, and just go, the installation can be done in "as little as a few weeks." Amazon says.
submitted by /u/dannylenwinn [link] [comments]
13h
Amazon rainforest could be gone within a lifetime
Researchers reveal the speed at which ecosystems of different sizes will disappear, once they have reached a point beyond which they collapse — transforming into an alternative ecosystem.
6h
An implant uses machine learning to give amputees control over prosthetic hands
submitted by /u/lokujj [link] [comments]
13h
An integrative approach to the facile functional classification of dorsal root ganglion neuronal subclasses [Neuroscience]
Somatosensory neurons have historically been classified by a variety of approaches, including structural, anatomical, and genetic markers; electrophysiological properties; pharmacological sensitivities; and more recently, transcriptional profile differentiation. These methodologies, used separately, have yielded inconsistent classification schemes. Here, we describe phenotypic differences in respo
7h
An Interview With James Dyson: Hair Care Products, EVs, Sustainability
One Dyson Corrale Hair
In a wide-ranging interview, the British entrepreneur talks about hair dryers, plastics, electric cars, and why he's not bothered by political controversy.
10h
An MXD1-derived repressor peptide identifies noncoding mediators of MYC-driven cell proliferation [Cell Biology]
MYC controls the transcription of large numbers of long noncoding RNAs (lncRNAs). Since MYC is a ubiquitous oncoprotein, some of these lncRNAs probably play a significant role in cancer. We applied CRISPR interference (CRISPRi) to the identification of MYC-regulated lncRNAs that are required for MYC-driven cell proliferation in the P493-6…
6h
An ultimate one-dimensional electronic channel in hexagonal boron nitride
In the field of 2-D electronics, the norm used to be that graphene is the main protagonist and hexagonal boron nitride (hBN) is its insulating passive support. Researchers of the Center for Multidimensional Carbon Materials (CMCM) within the Institute for Basic Science (IBS, South Korea) made a discovery that might change the role of hBN. They have reported that stacking of ultrathin sheets of hBN
12h
Ancient amber contains a cockroach—and a surprise
Ninety-nine-million-year-old fossil is a rare specimen indeed
2h
Ancient Shell Has Revealed Exactly How Much Shorter Days Were 70 Million Years Ago
The Moon was closer, too.
17h
Ants with giant heads show evolution can go 'backward'
Evolution isn't always a one-way street toward increasing specialization, according to new research. Occasionally, evolution can take a species back to a more generalist stage, the researchers report. Turtle ant soldiers scuttle around sporting shiny, adorably oversized heads. They use their heads to block the entrances of their nests—essentially acting as living doors. Not all heads are shaped a
11h
Approximating a kernel of truth
Machine learning tasks using very large data sets can be sped up significantly by estimating the kernel function that best describes the data.
10h
APS tip sheet: correlating matter's distribution in the universe with gamma rays
Scientists present the first direct cross-correlation between dark matter and gamma ray emissions.
9h
APS tip sheet: Understanding the tears of wine
New research explores the fluid dynamics behind a phenomenon known as tears of wine
9h
Are non-smoking young adults who use e-cigarettes more likely to smoke in the future?
Young people who have tried e-cigarettes but have never smoked before are nearly five times more likely to go on to try smoking, a new study has found. However, the findings do not provide clear support for the claim that e-cigarettes cause young people to start smoking (the so-called possible 'gateway effect').
49min
Arming the body's immune cells
Researchers at UC have discovered a previously unknown mechanism that could explain the reason behind decreased immune function in cancer patients and could be a new therapeutic target for immunotherapy for those with head and neck cancers.
9h
Around 100,000 convicted felons across US likely still own guns, say researchers
Around 100,000 convicted felons across the US still likely own a gun, despite being banned from doing so, concludes the first study of its kind, published online in Injury Prevention.
31min
Arrestin domain-containing 3 (Arrdc3) modulates insulin action and glucose metabolism in liver [Medical Sciences]
Insulin action in the liver is critical for glucose homeostasis through regulation of glycogen synthesis and glucose output. Arrestin domain-containing 3 (Arrdc3) is a member of the α-arrestin family previously linked to human obesity. Here, we show that Arrdc3 is differentially regulated by insulin in vivo in mice undergoing euglycemic-hyperinsulinemic…
6h
Asian inland wildfires driven by glacial-interglacial climate change [Earth, Atmospheric, and Planetary Sciences]
Wildfire can influence climate directly and indirectly, but little is known about the relationships between wildfire and climate during the Quaternary, especially how wildfire patterns varied over glacial–interglacial cycles. Here, we present a high-resolution soot record from the Chinese Loess Plateau; this is a record of large-scale, high-intensity fires over…
7h
Assessing the reliability of a clothing-based forensic identification [Computer Sciences]
A 2009 report by the National Academy of Sciences was highly critical of many forensic practices. This report concluded that significant changes and advances were required to ensure the reliability across the forensic sciences. We examine the reliability of one such forensic technique used for identification based on purported distinct…
7h
Astronauter odlar sallad i rymden
Sedan 2014 har man med framgång odlat sallat i rymden. I en ny studie visar forskare att den är ätbar och lika nyttig som på jorden. Tillgången till annat än dagens paketerade mat i rymden är avgörande för längre resor i rymden. Vad kommer egentligen stå på rymdmenyn i framtiden?
12h
Astronomers Have Found a Peculiar New Type of Star That Only Pulses on One Side
The first time we've ever seen something like this.
18h
Astronomers pinpoint rare binary brown dwarf
Astronomers working on 'first light' results from a newly commissioned telescope in Chile made a chance discovery that led to the identification of a rare eclipsing binary brown dwarf system.
6h
Astronomers use slime mold model to reveal dark threads of the cosmic web
A computational approach inspired by the growth patterns of a bright yellow slime mold has enabled a team of astronomers and computer scientists to trace the filaments of the cosmic web that connects galaxies throughout the universe.
6h
Atomic force microscopy: New sensing element for high-speed imaging
With atomic force microscopy, tiny structures can be imaged. But usually there is a trade of: In order to create pictures quickly, very stiff materials have to be used in the microscope, but they can damage delicate structures such as living cells. Scientists have now found a way around this dilemma.
21h
Author Correction: A dog oviduct-on-a-chip model of serous tubal intraepithelial carcinoma
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61782-w
1d
Author Correction: A novel homozygous mutation in GAD1 gene described in a schizophrenic patient impairs activity and dimerization of GAD67 enzyme
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61779-5
1d
Author Correction: A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61783-9
1d
Author Correction: A semi-automated virtual workflow solution for the design and production of intraoral molding plates using additive manufacturing: the first clinical results of a pilot-study
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61778-6
1d
Author Correction: Accurate signal-source localization in brain slices by means of high-density microelectrode arrays
Scientific Reports, Published online: 11 March 2020; doi:10.1038/s41598-020-61780-y
58min
Author Correction: Clinical and serological evaluation of capybaras (Hydrochoerus hydrochaeris) successively exposed to an Amblyomma sculptum-derived strain of Rickettsia rickettsii
Scientific Reports, Published online: 11 March 2020; doi:10.1038/s41598-020-61342-2 Author Correction: Clinical and serological evaluation of capybaras ( Hydrochoerus hydrochaeris ) successively exposed to an Amblyomma sculptum -derived strain of Rickettsia rickettsii
58min
Author Correction: Influence of the magnetic field on bandgap and chemical composition of zinc thin films prepared by sparking discharge process
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61009-y
13h
Author Correction: Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-14964-z
13h
Author Correction: Subsurface ocean flywheel of coupled climate variability in the Barents Sea hotspot of global warming
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61544-8
1d
Author Correction: Synthesis and characterization of polyethylene glycol-phenol-formaldehyde based polyurethane composite
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61553-7
13h
Author Correction: Targeted memory reactivation during sleep boosts intentional forgetting of spatial locations
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61784-8
1d
Backyard in Mexico yields lost Maya kingdom
The long-lost capital of the ancient Maya kingdom Sak Tz'i' has turned up in the backyard of a Mexican cattle rancher. Charles Golden, associate professor of anthropology at Brandeis University, in collaboration with Brown University bioarchaeologist Andrew Scherer, and a team of researchers from Mexico, Canada, and the United States, began excavating the site in June 2018. Among their findings i
5h
Bacteria sacrifice themselves when under attack to save their colonies
Some bacteria sacrifice themselves when their colony is attacked by rivals, to save their relatives and make sure their shared genes are passed on
7h
Banebrydende forskning: Nu kan uddøde arter snart vækkes til live
Op mod en million dyre- og plantearter er lige nu truet af udryddelse.
19h
Behind the mask: In search of gorilla-friendly tourism
Rwanda, land of a thousand invisible hills. It's an overcast morning in Kigali, capital of Africa's most densely populated country. The sound of a bamboo broom scraping the tarmac accompanies a solitary sweeper engaged in the Sisyphean task of keeping the hotel frontage spick and span. Overhead, a black kite looms into view. Then another, then a third, swooping down like dementors out of the mist.
9h
Bioinspired underwater locomotion of light-driven liquid crystal gels [Applied Physical Sciences]
Soft-bodied aquatic invertebrates, such as sea slugs and snails, are capable of diverse locomotion modes under water. Recapitulation of such multimodal aquatic locomotion in small-scale soft robots is challenging, due to difficulties in precise spatiotemporal control of deformations and inefficient underwater actuation of existing stimuli-responsive materials. Solving this challenge and…
7h
Biology researchers capture shape-shifting delivery structures in body's 'cellular FedEx system'
A new cellular biology study, published last month in the journal Structure by scientists at Vanderbilt, reports a shape-shifting structure in the human body which plays an important role in the timely delivery of fats and proteins.
11h
Biomass fuels can significantly mitigate global warming. When compared with petroleum only emissions, ethanol with bioenergy was 78-290% better in reducing carbon emissions; ethanol was 204-416% improved, biomass powered electric vehicles powered by biomass was 74-303% cleaner
submitted by /u/Wagamaga [link] [comments]
13h
Birds of a feather really do flock together
A species of tiny bird, found on a small island has evolved into five different color variations depending on where on the island it lives.
10h
Bologna cover-up at Oxford University Press
This is the second part of the Bologna whistleblower account. As the university was burying their own misconduct findings, Oxford University Press and their ignoble editor were busy punishing and gaslighting the whistleblower.
18h
Boosting stability of perovskites helps silicon solar cells
A change in chemical composition enabled scientists to boost the longevity and efficiency of a perovskite solar cell.
8h
Bottlebrush polymers in the melt and polyelectrolytes in solution share common structural features [Chemistry]
Uncharged bottlebrush polymer melts and highly charged polyelectrolytes in solution exhibit correlation peaks in scattering measurements and simulations. Given the striking superficial similarities of these scattering features, there may be a deeper structural interrelationship in these chemically different classes of materials. Correspondingly, we constructed a library of isotopically labeled bot
7h
Bouquets of nanoflowers with a golden touch
Using nano-sized spheres as a starting point, researcher Juan Wang of the University of Twente (MESA+ Institute) creates fascinating structures that can have a wide range of shapes and functionalities. They can even achieve a beautiful flower-like appearance with nanowires connected by gold nanospheres. The new nanostructures can be designed for detecting chemical or biological substances at their
9h
Brain activity forecasts video engagement in an internet attention market [Psychological and Cognitive Sciences]
The growth of the internet has spawned new "attention markets," in which people devote increasing amounts of time to consuming online content, but the neurobehavioral mechanisms that drive engagement in these markets have yet to be elucidated. We used functional MRI (FMRI) to examine whether individuals' neural responses to videos…
6h
Brazilian toads that eat scorpions can survive the venom of 10 stings
Brazil's yellow cururu toads eat scorpions, and they can survive five times the dose of scorpion venom that would kill a mouse – the same as 10 stings
6h
Bread machines for any toasty kitchen
Stay fresh. (Jude Infantini via Unsplash/) Think for a second how ingrained bread is in our culture. We "break bread" with family, friends, and frenemies as a way of problem solving. It's a slang term for money. The value of new inventions is still rated against sliced bread. So, if you're going to start making such a time-honored concoction as the humble loaf of bread, you'll want a gadget that
4h
Bulb size matters: Uncovering the evolution of the plant kingdom's doomsday preppers
Bulbs are doomsday preppers, storing up resources underground to ride out disaster. The bigger the bulb, the bigger the stockpile. So, how come their sizes vary so much?
1d
Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-15061-x Synthetic RNA-based circuits allow for gene regulation without the risk of mutagenesis. Here the authors demonstrate a Caliciviral VPg-based Translational activator which allows translational activation of synthetic mRNAs.
13h
California Cracks Down on Alternative Health Plans
State insurance regulators accused a ministry offering an alternative to traditional insurance of misleading consumers.
6h
Cancer cells spread using a copper-binding protein
Researchers at Chalmers University of Technology, Sweden, have shown that the Atox1 protein, found in breast cancer cells, participates in the process by which cancer cells metastasise. The protein could therefore be a potential biomarker for assessing the aggressiveness of the disease, as well as a possible target for new drugs. The research was recently published in the journal PNAS.
19h
Cancerceller bildar metastaser med hjälp av kopparbindande protein
Proteinet Atox1, som finns i bröstcancerceller, deltar i den process som gör att cancercellerna bildar metastaser. Det kopparbindande proteinet kan därmed både bli en möjlig biomarkör för sjukdomens aggressivitet, och en möjlig måltavla för nya läkemedel, enligt forskare vid Chalmers. Bröstcancer är den vanligaste cancerformen hos kvinnor världen över. Tidig diagnostisering och behandling är avgö
9h
Cancerous tumors, surrounding cells illuminated by new imaging agent
Scientists at Washington University School of Medicine in St. Louis have developed a new imaging agent that could let doctors identify not only multiple types of tumors but the surrounding normal cells that the cancer takes over and uses as a shield to protect itself from attempts to destroy it.
11h
Can't Stop Touching Your Face? Science Has Some Theories Why
Ground squirrels do it. So do human fetuses. How did we all end up with this unhygienic habit?
13h
Capillary transfer of soft films [Engineering]
Existing transfer technologies in the construction of film-based electronics and devices are deeply established in the framework of native solid substrates. Here, we report a capillary approach that enables a fast, robust, and reliable transfer of soft films from liquid in a defect-free manner. This capillary transfer is underpinned by…
7h
Carbon emissions from the global electricity system fell by 2% last year, the biggest drop in almost 30 years, as countries began to turn their backs on coal-fired power plants.
submitted by /u/Wagamaga [link] [comments]
13h
Case Western Reserve University research finds high rates of trauma exposure, PTSD symptoms for those in drug court
Nearly 94% of defendants in Cuyahoga County drug court have been exposed to trauma and many suffer from symptoms of post-traumatic stress disorder (PTSD), according to a new Case Western Reserve University study.
8h
CD300f immunoreceptor is associated with major depressive disorder and decreased microglial metabolic fitness [Immunology and Inflammation]
A role for microglia in neuropsychiatric diseases, including major depressive disorder (MDD), has been postulated. Regulation of microglial phenotype by immune receptors has become a central topic in many neurological conditions. We explored preclinical and clinical evidence for the role of the CD300f immune receptor in the fine regulation of…
6h
Cerebellar plasticity and associative memories are controlled by perineuronal nets [Neuroscience]
Perineuronal nets (PNNs) are assemblies of extracellular matrix molecules, which surround the cell body and dendrites of many types of neuron and regulate neural plasticity. PNNs are prominently expressed around neurons of the deep cerebellar nuclei (DCN), but their role in adult cerebellar plasticity and behavior is far from clear….
6h
Chemists create new artificial enzyme
Computational chemists have created a novel, synthetic, three-stranded molecule that functions just like a natural metalloenzyme, or an enzyme that contains metal ions.
3h
Children and teens worry about political issues
A new psychological study suggests that children and teens are worried about political issues, though it's unclear that children's and teens' worry is a cause for concern, or that it is interfering with their mental health functioning.
5h
Chip for liquid biopsy will help to detect prostate cancer
Researchers of Sechenov University together with their colleagues from Australia used the microfluidics technology to develop a device able to isolate cancer cells from urine of patients with prostate cancer. The study showed high sensitivity and specificity of the new method in diagnosing prostate cancer. The results obtained were published in Cancers.
10h
Circulatory failure is predictable
Researchers have developed a method for predicting circulatory failure in patients in intensive care units — enabling clinicians to intervene at an early stage. Their approach uses machine learning methods to evaluate an extensive body of patient data.
8h
Cirklens kvadratur – og tre andre uløselige geometriske problemer
PLUS. I en ny bog tager en amerikansk matematikprofessor os med på en 2.000 år lang geometrisk rejse.
10h
Collagen can withstand more strain than previously known
Researchers in the Department of Physics at King's College London have discovered that collagen fibrils can withstand a significantly higher amount of strain than previously thought, broadening our understanding of tissue mechanics.
9h
Collective dynamics of active matter systems
A study provides new details about the collective motion of individual agents in a liquid-crystal-like system, which could help in better understanding bacterial colonies, structures and systems in the human body, and other forms of active matter.
1d
Columbia study evaluates cervical cancer risks of IUDs
Patients who used copper intrauterine devices were found to have a lower risk of cervical cancer compared to users of the levonorgestrel-releasing intrauterine system.
5h
Common feed ingredient tested safe in bulls
Cattle feeders choose distillers grains in feedlot diets as an inexpensive alternative to corn and soybean meal. But until now, no one had studied the effects of the common feed ingredient on bull development and fertility. With bull fertility to blame for a significant portion of reproductive failures in cow-calf operations, University of Illinois researchers decided it was worth a look.
9h
Community factors influence how long you'll live, study shows
While lifestyle choices and genetics go a long way toward predicting longevity, a new study shows that certain community characteristics also play important roles. American communities with more fast food restaurants, a larger share of extraction industry-based jobs, or higher population density have shorter life expectancies, according to researchers.
6h
Confessions of an Ex–Never Trumper
She had to sleep on it. The letter was in her inbox; friends and colleagues, throughout the Republican national-security circles where Rebeccah Heinrichs had made her career, were signing on. It called then-candidate Donald Trump "fundamentally dishonest" and claimed that if elected president, he would use his power "in ways that make America less safe." She wasn't crazy about the tone in some sp
12h
Construction Workers Embrace the Robots That Do Their Jobs
A robotic excavator can dig a pipeline trench without a human in the cab. An engineers' union is partnering with the company that makes the tech.
9h
Core Concept: Liquid metal renaissance points to wearables, soft robots, and new materials [Chemistry]
When chemical engineer Michael Dickey talks about his research on liquid metals, he knows what to expect. "People usually say mercury or the Terminator," he says, alluding to the shape-shifting killer robot from the 1992 movie Terminator 2: Judgment Day. Even many researchers, he says, aren't familiar with the unique…
7h
Correction for Cristopher Bragg et al., Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1 [Corrections]
NEUROSCIENCE Correction for "Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1," by D. Cristopher Bragg, Kotchaphorn Mangkalaphiban, Christine A. Vaine, Nichita J. Kulkarni, David Shin, Rachita Yadav, Jyotsna Dhakal, Mai-Linh Ton, Anne Cheng, Christopher T. Russo, Mark Ang, Patrick Acuña,…
6h
Correction for Hsu et al., Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration [Corrections]
IMMUNOLOGY AND INFLAMMATION Correction for "Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration," by Alan Y. Hsu, Decheng Wang, Sheng Liu, Justice Lu, Ramizah Syahirah, David A. Bennin, Anna Huttenlocher, David M. Umulis, Jun Wan, and Qing Deng, which was first published August 26, 2019;…
6h
Correction for Jiang et al., Reactivation of Epstein-Barr virus by a dual-responsive fluorescent EBNA1-targeting agent with Zn2+-chelating function [Corrections]
CELL BIOLOGY Correction for "Reactivation of Epstein–Barr virus by a dual-responsive fluorescent EBNA1-targeting agent with Zn2+-chelating function," by Lijun Jiang, Hong Lok Lung, Tao Huang, Rongfeng Lan, Shuai Zha, Lai Sheung Chan, Waygen Thor, Tik-Hung Tsoi, Ho-Fai Chau, Cecilia Boreström, Steven L. Cobb, Sai Wah Tsao, Zhao-Xiang Bian, Ga-Lai Law,…
7h
Correction for Shi et al., Deep elastic strain engineering of bandgap through machine learning [Corrections]
ENGINEERING Correction for "Deep elastic strain engineering of bandgap through machine learning," by Zhe Shi, Evgenii Tsymbalov, Ming Dao, Subra Suresh, Alexander Shapeev, and Ju Li, which was first published February 15, 2019; 10.1073/pnas.1818555116 (Proc. Natl. Acad. Sci. U.S.A. 116, 4117–4122). The authors note that "In Fig. 2A, the 6D…
6h
Correction to Supporting Information for Zhou et al., Perfluorocarbon nanoparticle-mediated platelet inhibition promotes intratumoral infiltration of T cells and boosts immunotherapy [SI Correction]
MEDICAL SCIENCES Correction to Supporting Information for "Perfluorocarbon nanoparticle-mediated platelet inhibition promotes intratumoral infiltration of T cells and boosts immunotherapy," by Zaigang Zhou, Baoli Zhang, Wenjing Zai, Lin Kang, Ahu Yuan, Yiqiao Hu, and Jinhui Wu, which was first published May 29, 2019; 10.1073/pnas.1901987116 (Proc. Natl. Acad. Sci. U.S.A. 116,…
7h
Crosstalk captured between muscles, neural networks in biohybrid machines
A platform designed for coculturing a neurosphere and muscle cells allows scientists to capture the growth of neurons toward muscles to form neuromuscular junctions.
8h
Cryo-EM reveals unexpected diversity of photosystems
Annemarie Perez Boerema from Alexey Amunts lab has reconstructed the atomic models of new forms of Photosystem I in collaboration with scientists from Israel and China. The studies, published in two Nature Plants articles, expand on the fundamental understanding of how bioenergetic complexes are assembled and regulated in the photosynthetic membranes of cyanobacteria and algae.
12h
Cryo-EM structure of rhinovirus C15a bound to its cadherin-related protein 3 receptor [Microbiology]
Infection by Rhinovirus-C (RV-C), a species of Picornaviridae Enterovirus, is strongly associated with childhood asthma exacerbations. Cellular binding and entry by all RV-C, which trigger these episodes, is mediated by the first extracellular domain (EC1) of cadherin-related protein 3 (CDHR3), a surface cadherin-like protein expressed primarily on the apical surfaces…
6h
Custom-Made Bones Are Being 3D Printed in a Lab Then Implanted in People
submitted by /u/dwaxe [link] [comments]
13h
CUX1 and I{kappa}B{zeta} (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts [Systems Biology]
The role of stromal fibroblasts in chronic inflammation is unfolding. In rheumatoid arthritis, leukocyte-derived cytokines TNF and IL-17A work together, activating fibroblasts to become a dominant source of the hallmark cytokine IL-6. However, IL-17A alone has minimal effect on fibroblasts. To identify key mediators of the synergistic response to TNF…
7h
Daily briefing: Two physicists' playful bet hinges on topological quantum computer
Nature, Published online: 10 March 2020; doi:10.1038/d41586-020-00713-1 A pizza hangs in the balance in a bet over the progress of quantum computing. Plus, how transgenic animal models are advancing the fight against the coronavirus and a chance to win one of the most-loved Quirks of Nature cartoons ever.
6h
Danske læger skal engagere sig i klimadebatten
Sundhedsvæsenet bidrager til mere end seks pct. af den samlede danske CO2-udledning mod flyindustriens tre pct. Derfor skal læger engagere sig i klimadebatten, skriver en række læger.
9h
Day Was Shorter 70 Million Years Ago
What does an extinct mollusk have to do with the Moon? This is one of those amazing science stories that ties together multiple disciplines and lines of evidence into one elegant narrative. In this case a detailed analysis of a 70 million year old mollusk shell has given scientists a critical piece of information that will help them model the Earth-Moon system. Let's start with the Moon – astrono
12h
DBC1, p300, HDAC3, and Siah1 coordinately regulate ELL stability and function for expression of its target genes [Biochemistry]
Among all of the Super Elongation Complex (SEC) components, ELL1 (also known as ELL) is the only bona fide elongation factor that directly stimulates transcription elongation by RNA polymerase II. However, the mechanism(s) of functional regulation of ELL1 (referred to as ELL hereafter), through its stabilization, is completely unknown. Here,…
6h
Debat: Skal fornuften eller grådigheden sejre?
PLUS. EU står ved en skillevej, hvor det skal afgøres, om forædlingen af planter skal komme alle til gode, eller om det skal gøres til en ulidelig juridisk slagmark i de kommende mange år.
8h
'Deceptively simple' process could boost plastics recycling
Plastics are a victim of their own success, so inexpensive, easy to use and versatile that the world is awash in plastic waste. Now researchers have reported a new method of producing polyolefins — made from hydrocarbons and the most common building block of plastics — structured to address one of the biggest stumbling blocks to plastics recycling.
1d
Deciphering disorder: 2-D materials are surprisingly imperfect
The next wave of quantum, optical and electronic devices will be built from powerful two-dimensional materials. These materials can host room temperature qubits thereby enabling solid-state quantum technologies that are inherently more powerful than their classical counterparts.
10h
Decorating bacteria with self-assembled synthetic receptors
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-14336-7 Cell surface proteins mediate the interactions between cells and their extracellular environment. Here the authors design synthetic biomemetic receptor-like sensors that facilitate programmable interactions between bacteria and their target.
13h
Defects in nanosilica catalytically convert CO2 to methane without any metal and ligand [Engineering]
Active and stable metal-free heterogeneous catalysts for CO2 fixation are required to reduce the current high level of carbon dioxide in the atmosphere, which is driving climate change. In this work, we show that defects in nanosilica (E′ centers, oxygen vacancies, and nonbridging oxygen hole centers) convert CO2 to methane…
6h
Delayed negative effects of prosocial spending on happiness [Economic Sciences]
Does prosocial behavior promote happiness? We test this longstanding hypothesis in a behavioral experiment that extends the scope of previous research. In our Saving a Life paradigm, every participant either saved one human life in expectation by triggering a targeted donation of 350 euros or received an amount of 100…
6h
Demographics linked to choice not to vaccinate children in Texas, study finds
Texans who are college-educated, live in suburban or urban areas, have higher median incomes and are ethnically white are less likely to vaccinate their children, according to analysis by researchers at the University of Texas at Austin.
5h
Designing heterotropically activated allosteric conformational switches using supercharging [Biophysics and Computational Biology]
Heterotropic allosteric activation of protein function, in which binding of one ligand thermodynamically activates the binding of another, different ligand or substrate, is a fundamental control mechanism in metabolism and as such has been a long-aspired capability in protein design. Here we show that greatly increasing the magnitude of a…
7h
Detailed Tests Show Space-Grown Lettuce Is as Safe And Nutritious as Earth Lettuce
Astronauts' diets are about to get more varied.
23h
Developing the Ternary ZnO Doped MoS2 Nanostructures Grafted on CNT and Reduced Graphene Oxide (RGO) for Photocatalytic Degradation of Aniline
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61367-7 Developing the Ternary ZnO Doped MoS 2 Nanostructures Grafted on CNT and Reduced Graphene Oxide (RGO) for Photocatalytic Degradation of Aniline
13h
Diabetes risk: what's driving the global rise in obesity rates?
The 'urbanisation of rural life' may be more significant than migration to cities
19h
Dietary modification, penetrance, and the origins of congenital malformation [Medical Sciences]
Molecular genetic diagnostics refers to the branch of clinical medicine dedicated to finding the proximate mutational cause of an abnormality (1). More for practical than theoretical reasons, it generally assumes that a genetic variant is both necessary and sufficient to cause the defect, and hence that there is no need…
7h
Differences between self-identified general practitioners and board-certified family doctors
Physicians who identify as 'general practitioners' are a group distinct from board-certified 'family physicians,' according to a new study that was supported, in part, by the American Board of Family Medicine Foundation. The authors recommend that GPs and FPs be considered separate groups for research, workforce and policy purposes.
1d
Dinoflagellates with relic endosymbiont nuclei as models for elucidating organellogenesis [Evolution]
Nucleomorphs are relic endosymbiont nuclei so far found only in two algal groups, cryptophytes and chlorarachniophytes, which have been studied to model the evolutionary process of integrating an endosymbiont alga into a host-governed plastid (organellogenesis). However, past studies suggest that DNA transfer from the endosymbiont to host nuclei had already…
7h
Disaster-zone research: participants should benefit too
Nature, Published online: 10 March 2020; doi:10.1038/d41586-020-00696-z
13h
Discovered: Why obesity causes high blood pressure — and potential ways to fix
Researchers have determined precisely how obesity causes high blood pressure and even reversed it in lab models.
9h
Discovery points to origin of mysterious ultraviolet radiation
Lyman-alpha blobs (LABs) are gigantic clouds of hydrogen gas that produce a special type of ultraviolet light known as Lyman-alpha emission. An extremely powerful energy source must produce this radiation, but scientists debate what that energy source is. A study of Lyman-alpha blob 6 (LAB-6) is the first LAB with strong evidence of an infalling gas feature. The findings suggest that star-forming
1d
Disease-causing virus manipulates crop plants to favor its vector
The virus that causes barley yellow dwarf, the most widespread disease of cereal crops, manipulates its host plant and insect vector to promote its own survival, according to an international team of researchers. The group found that the virus raises the temperature of its host plants along with the heat-tolerance of its aphid vectors to create regions on the plants where aphids can feed free from
9h
Disturbed retinal gene function underlying canine blindness
A canine study carried out at the University of Helsinki has described a gene variant in the regulatory region of the retina resulting in the abnormal function of retinal genes and, eventually, in the loss of vision in dogs. The study can benefit the diagnostics and treatment of retinitis pigmentosa, a disease suffered by two million human beings globally.
10h
Diverse nanostructures underlie thin ultra-black scales in butterflies
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-15033-1 Nature has developed the ability to produce a wide range of optical effects most notably in the butterfly wing. Here, the authors report on the analysis of the structures responsible for ultra-black coloration across different butterflies and combine this with modelling to identify the key characteristics
13h
Division of labor and growth during electrical cooperation in multicellular cable bacteria [Microbiology]
Multicellularity is a key evolutionary innovation, leading to coordinated activity and resource sharing among cells, which generally occurs via the physical exchange of chemical compounds. However, filamentous cable bacteria display a unique metabolism in which redox transformations in distant cells are coupled via long-distance electron transport rather than an exchange…
7h
Do Your DNA Duty: Collect Wild Animal Poop and Dog Saliva for Science
You can help collect data for scientific studies by mailing researchers your dog's saliva, samples of the forest floor and even spiny anteater scat.
21h
Docking, rendezvous and Newton's third law – the challenge of servicing satellites in space
If you want to build or fix something in space, you might think you'd need a human to do it. But what if you didn't? What if robotic spacecraft could be used to refuel satellites in orbit, add new instruments to outdated machinery and even build entire structures while in space?
9h
Does lack of paid sick time make US susceptible to global health crisis?
Robert Bruno is a professor of labor and employment relations at the Urbana campus of the University of Illinois and the director of the Labor Education Program in Chicago. Bruno, an expert in labor history and politics, spoke with News Bureau business and law editor Phil Ciciora about the lack of paid sick leave in the U.S.
11h
Don't blame tech for your distracted brain. Take control.
Technology and devices aren't inherently distracting, says behavioral design expert Nir Eyal. Distraction comes from internal triggers of discomfort. So, the answer to avoiding distraction isn't a total digital detox, but instead developing healthy ways of identifying and coping with these internal triggers. Eyal points to three main strategies: reimagining the trigger as a sensation of curiosity
14h
Dramatic increase in bowel cancer in young adults in England
There has been a dramatic increase in the incidence of bowel cancer in adults under the age of 50, according to new research from the University of Bristol, UWE Bristol and University Hospitals Bristol NHS Foundation Trust (UH Bristol).
10h
Drones, Bio-economy, and Io T to change perception, function, and role of Amazon rain forest and the communities it homes.
submitted by /u/MannySol123 [link] [comments]
13h
Dynamics of life expectancy and life span equality [Social Sciences]
As people live longer, ages at death are becoming more similar. This dual advance over the last two centuries, a central aim of public health policies, is a major achievement of modern civilization. Some recent exceptions to the joint rise of life expectancy and life span equality, however, make it…
7h
Dyson Corrale Hair Straightener: Features, Release Date, Price
One Dyson Corrale Hair
We tried the company's $500 Corrale straightener, which claims to smooth hair with more precision—and less damage.
10h
Electrical power generation from moderate-temperature radiative thermal sources
Moderate-temperature thermal sources often radiate waste heat as a by-product of mechanical work, chemical or nuclear reactions, or information processing. In a new report in Science, Paul S. Davids and a research team at the Sandia National Laboratory in the U.S., demonstrated the conversion of thermal radiation into electrical power. For this, they used a bipolar grating-coupled complimentary me
10h
Elon Musk dismisses astronomy concerns over Starlink network
Musk SpaceX Starlink
SpaceX founder Elon Musk on Monday dismissed scientists' concerns that his company's Starlink constellation of internet satellites would obscure the view of the night sky, predicting the network "will not cause any impact whatsoever in astronomical discoveries."
15h
Elon Musk: My Main Goal Is to Get Humanity to Mars Before I Die
Mars or Die At the Satellite 2020 conference in Washington Monday, SpaceX CEO Elon Musk told a crowd of industry insiders and journalists that his biggest concern is to get people to Mars before he dies. "If we don't improve our pace of progress, I'm definitely going to be dead before we go to Mars," Musk said, as quoted by Bloomberg . "If it's taken us 18 years just to get ready to do the first
6h
EPA's proposed transparency rule: Factors to consider, many; planets to live on, one [Editorials]
"In God we trust. All others bring data." So reads a T-shirt sold by the American Statistical Association. This pithy quip encapsulates a fundamental principle of science: Scientists rely on evidence rather than authority. Indeed, "doubt has been considered essential to science since long before the scientific method was established…
7h
Equity valuations: keep your powder dry
Even on optimistic assumptions US shares are still too expensive
7h
Estimation and model selection in general spatial dynamic panel data models [Statistics]
Commonly used methods for estimating parameters of a spatial dynamic panel data model include the two-stage least squares, quasi-maximum likelihood, and generalized moments. In this paper, we present an approach that uses the eigenvalues and eigenvectors of a spatial weight matrix to directly construct consistent least-squares estimators of parameters of…
7h
Etiopisk havariundersøgelse giver Boeing den fulde skyld for MAX-styrt
De etiopiske piloter måtte opgive manuelt at rette haleplan ud, da de havde slukket for det automatiske MCAS, der var ved at sende deres fly i jorden.
9h
Evaluation of a concerted vs. sequential oxygen activation mechanism in {alpha}-ketoglutarate-dependent nonheme ferrous enzymes [Biochemistry]
Determining the requirements for efficient oxygen (O2) activation is key to understanding how enzymes maintain efficacy and mitigate unproductive, often detrimental reactivity. For the α-ketoglutarate (αKG)–dependent nonheme iron enzymes, both a concerted mechanism (both cofactor and substrate binding prior to reaction with O2) and a sequential mechanism (cofactor binding and…
7h
Every part of Blue Origin's new Glenn rocket is gigantic, including its nose cone
Massive. Enormous. Huge. Gigantic. And whatever other words you find in the thesaurus all do the job when it comes to describing Blue Origin's New Glenn Rocket. Especially its nosecone.
9h
Evidence of metasomatism in the interior of Vesta
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-15049-7 The authors here analyse the petrology of the meteorite NWA 8321 (parent body Vesta). They find sulfidation processes of olivine suggesting metasomatism in the Vestan interior and a partial melting origin for the host noritic diogenite.
13h
Exciting apparatus helps atoms see the light
Researchers have generated Rydberg atoms – unusually large excited atoms – near nanometer-thin optical fibers. Their findings mark progress toward a new platform for quantum information processing, which has the potential to revolutionize material and drug discoveries and provide more secure quantum communication.
7h
Exciting tweaks for organic solar cells
A molecular tweak has improved organic solar cell performance, bringing us closer to cheaper, efficient, and more easily manufactured photovoltaics. The new design approach targets the molecular backbone of the cell's power-generating layer.
21h
Exclusive: How Google Uses Machine Learning to Analyze Soccer Moves
How powerful is your kick? Did you pass effectively? The latest Jacquard wearable uses machine learning to scrutinize a player's footwork in real time.
15h
Exclusive: Ricoh's 360 Camera Division Spins Out to Form Vecnos
Vecnos wants to make 360-degree content mainstream, starting with its first compact and wand-like camera.
1d
Experts call for more support for parents of children with genetic learning disabilities
Parents of children with genetic conditions that cause learning disabilities are at risk of mental health problems, suggests new research published today in the British Journal of Psychiatry. The teams behind the study have called for greater support for parents whose child receives a genetic diagnosis for their learning disability.
49min
Exploring long-range cooperativity in the 20S proteasome core particle from Thermoplasma acidophilum using methyl-TROSY-based NMR [Biophysics and Computational Biology]
The 20S core particle (CP) proteasome is a molecular assembly catalyzing the degradation of misfolded proteins or proteins no longer required for function. It is composed of four stacked heptameric rings that form a barrel-like structure, sequestering proteolytic sites inside its lumen. Proteasome function is regulated by gates derived from…
7h
Fatal overproduction of antibodies
Bone marrow plasma cells produce antibodies. These comprise two long and two short protein chains. The pathological proliferation of plasma cells can lead to an overproduction of the short chains. These associate to fibrils and deposit in organs. The result is fatal organ failure. A research team from the Technical University of Munich (TUM) and Heidelberg University has now identified the mutatio
10h
Feeding fusion: hydrogen ice pellets prove effective for fueling fusion plasmas
Injecting pellets of hydrogen ice rather than puffing hydrogen gas improves fusion performance. Studies by PPPL and ORNL physicists compared the two methods on the DIII-D National Fusion Facility, looking ahead to the fueling to be used on ITER.
4h
Feeding wildlife can disrupt animal social structures
A team of researchers from the University of Georgia and San Diego State University has found that the practice of feeding wildlife could be more detrimental to animals than previously thought.
9h
Fluctuation-response inequality out of equilibrium [Physics]
We present an approach to response around arbitrary out-of-equilibrium states in the form of a fluctuation–response inequality (FRI). We study the response of an observable to a perturbation of the underlying stochastic dynamics. We find that the magnitude of the response is bounded from above by the fluctuations of the…
6h
Footprints of natural selection at the mannose-6-phosphate isomerase locus in barnacles [Evolution]
The mannose-6-phosphate isomerase (Mpi) locus in Semibalanus balanoides has been studied as a candidate gene for balancing selection for more than two decades. Previous work has shown that Mpi allozyme genotypes (fast and slow) have different frequencies across Atlantic intertidal zones due to selection on postsettlement survival (i.e., allele zonation)….
7h
Four angles on the global struggle against diabetes
Healthcare workers, scientists and politicians are contending with a big increase in patient numbers
19h
Fragment of Planet That Hit Earth May Be Buried Inside Moon
Where did the Moon come from and how was it formed? It's a question that scientists have been scratching their heads over for decades. According to the widely-accepted " giant-impact hypothesis ," the Moon was formed billions of years ago when a Mars-sized planet called Theia collided with the Earth, breaking off a large chunk in the process. Now, researchers from the University of New Mexico say
3h
Fresh groundwater flow important for coastal ecosystems
Groundwater is the largest source of freshwater, one of the world's most precious natural resources and vital for crops and drinking water. It is found under our very feet in the cracks and pores in soil, sediments and rocks. Now an international research team led by the University of Göttingen has developed the first global computer model of groundwater flow into the world's oceans. Their analysi
12h
From darkness to light: New findings unravel how plants control energy generation
Researchers at Western Sydney University and The Australian National University have discovered new chemical communication pathways that determine how a plant changes when it emerges from darkness in the soil to light.
12h
From the archive
Nature, Published online: 10 March 2020; doi:10.1038/d41586-020-00577-5 How Nature reported efforts in 1970 to assess the economic benefits of scientific discoveries, and an update from 1870 on the search for the cause of malaria.
10h
Frost-free zone on macrotextured surfaces [Applied Physical Sciences]
Numerous studies have focused on designing functional surfaces that delay frost formation or reduce ice adhesion. However, solutions to the scientific challenges of developing antiicing surfaces remain elusive because of degradation such as mechanical wearing. Inspired by the discontinuous frost pattern on natural leaves, here we report findings on the…
6h
FT Health: Combating Diabetes
Over 460m people worldwide have diabetes, a figure that is projected to reach 700m by 2045. This report looks at the factors behind this rise, the latest high-tech solutions, and how health services are coping — or failing to
19h
Fågelfamiljen astrilders släktträd nu rekonstruerat
Den mest omfattande studien av släktträdet för fågelfamiljen astrilder, eller praktfinkar, visar att den gemensamme förfadern levde för 11 miljoner år sedan. Forskare vid Göteborgs och Uppsala universitet har analyserat drygt 80 procent av världens cirka 145 arter av astrilder ( Estrildidae ) med hjälp av DNA. Gruppen omfattar några av de mest populära burfåglarna. Den nya studien drar slutsatsen
12h
Global analysis of LARP1 translation targets reveals tunable and dynamic features of 5' TOP motifs [Cell Biology]
Terminal oligopyrimidine (TOP) motifs are sequences at the 5′ ends of mRNAs that link their translation to the mTOR Complex 1 (mTORC1) nutrient-sensing signaling pathway. They are commonly regarded as discrete elements that reside on ∼100 mRNAs that mostly encode translation factors. However, the full spectrum of TOP sequences and…
7h
God, science, Mendel and Freeman Dyson | Letter
Brendan O'Brien points out that science and religion are not incompatible It is rather ironic that, in an editorial honouring the physicist Freeman Dyson, you should refer to another scientist, Gregor Mendel, as having "left science for God", as if science and religion were incompatible ( Thinkers make progress by getting things wrong as well as getting them right , Journal, 9 March). Your obitua
6h
Grad student names new treehopper species after Lady Gaga
According to Brendan Morris, a graduate student at the University of Illinois, treehoppers are the wackiest, most astonishing bugs most people have never heard of. They are morphological wonders, sporting bizarre protuberances that look like horns, gnarled branches, antlers or dead plant leaves. To draw attention to this group, Morris named a newly discovered treehopper species after Lady Gaga, a
10h
Green glow shows changes in gene expression
A new, versatile gene signal amplifier can do a better job of detecting the expression of target genes than current methods, researchers report. Ultimately, the researchers hope the two-module system will simplify the diagnosis of diseases like Alzheimer's, diabetes, and some cancers characterized by distinctive patterns of protein expression. They say it could also enable cell-based therapies by
9h
Hackinggrupper infiltrerer email-servere
Hackinggrupper med deres regering i ryggen er begyndt at udnytte en sårbarhed ved Microsoft Exchange, som skal give dem adgang til virksomheders kommunikation.
2h
Haunted by a Gene
For the first time, Nancy Wexler reveals that she has inherited the disease she has spent her life studying.
17h
Higher-rank zeta functions and SLn-zeta functions for curves [Mathematics]
In earlier papers L.W. introduced two sequences of higher-rank zeta functions associated to a smooth projective curve over a finite field, both of them generalizing the Artin zeta function of the curve. One of these zeta functions is defined geometrically in terms of semistable vector bundles of rank n over…
6h
Highly efficient organic photovoltaics with enhanced stability through the formation of doping-induced stable interfaces [Engineering]
Flexible organic photovoltaics (OPVs) are promising power sources for wearable electronics. However, it is challenging to simultaneously achieve high efficiency as well as good stability under various stresses. Herein, we demonstrate the fabrication of highly efficient (efficiency, 13.2%) and stable OPVs based on nonfullerene blends by a single-step postannealing treatment….
6h
High-throughput, combinatorial synthesis of multimetallic nanoclusters [Applied Physical Sciences]
Multimetallic nanoclusters (MMNCs) offer unique and tailorable surface chemistries that hold great potential for numerous catalytic applications. The efficient exploration of this vast chemical space necessitates an accelerated discovery pipeline that supersedes traditional "trial-and-error" experimentation while guaranteeing uniform microstructures despite compositional complexity. Herein, we rep
6h
HIV-1 uncoats in the nucleus near sites of integration [Microbiology]
HIV-1 capsid core disassembly (uncoating) must occur before integration of viral genomic DNA into the host chromosomes, yet remarkably, the timing and cellular location of uncoating is unknown. Previous studies have proposed that intact viral cores are too large to fit through nuclear pores and uncoating occurs in the cytoplasm…
7h
HKU paleontologists discover solid evidence of formerly elusive abrupt sea-level jump
Meltwater pulses (MWPs) known as abrupt sea-level rise will inevitably affect cities especially those on coastal plains of low elevation. A recent study published in Quaternary Science Reviews presented evidence of abrupt sea level change between 11,300-11,000 years ago in the Arctic Ocean, solving the puzzle of second largest meltwater pulse (labelled as "MWP-1B" next to the largest and already w
10h
HNRNPA1-induced spliceopathy in a transgenic mouse model of myotonic dystrophy [Medical Sciences]
Studies on myotonic dystrophy type 1 (DM1) have led to the RNA-mediated disease model for hereditary disorders caused by noncoding microsatellite expansions. This model proposes that DM1 disease manifestations are caused by a reversion to fetal RNA processing patterns in adult tissues due to the expression of toxic CUG RNA…
7h
Holi week and Italy on lockdown: Tuesday's best photos
The Guardian's picture editors select photo highlights from around the world Continue reading…
11h
Hospices struggle to deliver specialized support to children when a parent is dying
Support available to children experiencing the death of a parent varies across the country, new research published in the BMJ Supportive & Palliative Care finds.
1d
Hot time in the city: Urban lizards evolve heat tolerance
Faced with a gritty landscape of metal fences, concrete walls and asphalt pavement, city lizards in Puerto Rico rapidly and repeatedly evolved better tolerance for heat than their forest counterparts, according to new research. Studies that delve into how animals adapt in urban environments are still relatively rare. But anoles are becoming a model system for urban evolutionary research.
9h
Hotels benefit from marijuana legalization, study finds
Legalization of recreational marijuana may lead to increased hotel revenues, according to a Penn State researcher, who found that after legalizing marijuana, the City of Denver, Colorado, saw roughly $130 million in new hotel revenues.
11h
How a healthy sex life can earn you more money
A 2013 study associated more frequent sex with higher income rates. The initial hypothesis suggested that medical, psychological and physical positive effects of sexual activity could influence wage factors in working adults. Maslow's Hierarchy of Needs all tie in with a healthy sex life, according to several studies listed below. Scoring high on Maslow's Hierarchy of Needs is directly linked to
6h
How does the Brain Retrieve Memories?
submitted by /u/smallpocketlibrary [link] [comments]
2h
How heartbreak and hardship shape growing old
From being raised by an emotionally cold mother to experiencing violence, war and bereavement, difficult life events have a profound effect on our physical and mental wellbeing in later life — according to new research from the University of East Anglia.A new study published today shows how a range of life inequalities and hardships are linked to physical and mental health inequalities in later l
49min
How intermittent fasting changes liver enzymes and helps prevent disease
Research on mice reveals the surprising impact on fat metabolism and the role played by a regulator protein in the liver.
8h
How Long Could the World Run on Geothermal Power?
If everyone went 100 percent geothermal today, Earth's store of thermal energy would still outlive the sun.
10h
How menopause affects the brain | Lisa Mosconi
Many of the symptoms of menopause — hot flashes, night sweats, insomnia, memory lapses, depression and anxiety — start in the brain. How exactly does menopause impact cognitive health? Sharing groundbreaking findings from her research, neuroscientist Lisa Mosconi reveals how decreasing hormonal levels affect brain aging — and shares simple lifestyle changes you can make to support lifelong brai
9h
How plants protect themselves from sun damage
Chemists have observed, for the first time, one of the possible mechanisms that have been proposed for how plants dissipate energy when they are exposed to excess sunlight.
9h
How Rational Math Catches Slippery Irrational Numbers
When my students grow too dependent on their calculators, I ask them to find a number that, when multiplied by itself, gives them 2. Students quickly see that since 1² = 1 and 2² = 4, the answer has to be between 1 and 2. They square 1.1, 1.2, 1.3, and so on and discover that 1.4² = 1.96 and 1.5² = 2.25. "It's between 1.4 and 1.5," they say. "Good to know," I reply. "But come back when you can te
7h
How refugees succeed in visa reviews: New research reveals the factors that matter
Asylum seekers with legal representation are seven times more likely to succeed before the government tribunal tasked with reviewing refugee cases than those who represent themselves.
9h
How the moon formed: New research sheds light on what happened
How the Earth got its moon is a long debated question. The giant impact theory – which states that the moon formed from the a collision between the early Earth and a rocky body called Theia—has become the front runner among the explanations. But the details around how this happened are blurry and there are many observations that scientists are still struggling to explain.
11h
Här är framtidens bläck för tryckt elektronik
Genom att blanda två polymerer med olika egenskaper har en grupp forskare vid Linköpings universitet, fått fram ett organiskt material med superb ledningsförmåga, utan att det är dopat. För att öka ledningsförmågan och därmed få högre effektivitet i organiska solceller, lysdioder eller olika bioelektroniska applikationer har forskarna hittills "dopat" materialen med olika ämnen. Det här görs vanl
8h
I Really Wanted You to Love Warren
E lizabeth Warren's outgoing words to her staffers evoked the image of a boxing ring: "We left plenty of blood and teeth on the floor," she told them. Her voice didn't crack from sorrow, but just from making itself heard through whatever was left of her vocal cords. She went down a fighter, exhausted but not beaten. Exiting the primary race as the last plausible female nominee, she knew she didn'
7h
IKBFU Physicists keep improving 'smart' composites for biomedical sensors
The new composites are related to the multiferroic-class materials which have mutually controlled magnetic and electric properties. The effects observed in the compositions are considered to be a perspective platform for creating new devices from energy converters to highly sensitive sensors.
10h
Image of the Day: Scorpionfly Fossils
A piece of ancient amber found in a small Burmese village holds preserved remains that indicate this family of insects survived longer than the Early Cretaceous, as previously believed.
12h
Image: The foam-coarsening experiment aboard the ISS
Another fluid experiment joins long running research on foam stability on the International Space Station. The Foam-Coarsening experiment, developed by Airbus for ESA, is scheduled to be activated this month in the Fluid Science Laboratory in the European Columbus module.
12h
Immune cells against Alzheimer's?
German researchers have developed a novel, experimental approach against Alzheimer's. For this they collaborated with a US company. The approach is based on the stimulation of immune cells of the brain (microglia) by means of an antibody. The findings are reported in EMBO Molecular Medicine.
12h
Immuno-OpenPET: a novel approach for early diagnosis and image-guided surgery for small resectable pancreatic cancer
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61056-5
13h
Improving the collection of birth and death data worldwide
University of Melbourne researchers have identified and implemented the key interventions and tools that countries can — and should — use to improve the quality and availability of critical birth and death data and ultimately, improve health outcomes. Published in BMC Medicine, it is the first Civil Registration and Vital Statistics collection to report on experience in implementing technical in
10h
In This Issue [This Week in PNAS]
Animal lacking a mitochondrial genome Light microscope image of spores of H. salminicola from Chinook salmon. Aerobic respiration is a hallmark of eukaryotes but has been lost in several single-celled eukaryotic lineages adapted to low-oxygen environments. Whether certain animals also rely exclusively on anaerobic metabolism and have mitochondrion-related organelles (MROs)…
7h
Incompetence Exacerbated by Malevolence
Throughout the many disasters that have befallen the Trump administration, one theme has remained a constant: malevolence tempered by incompetence . That description emerged from a text-message conversation between the two of us in January 2017, the day after the release of the president's first travel ban. Chaos was erupting at ports of entry around the country. U.S. permanent residents were bei
13h
Increasing incidence of macular edema in excessive morning blood pressure surge in patients with retinal vein occlusion
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61386-4
13h
Indian Ocean phenomenon spells climate trouble for Australia
New international research by Woods Hole Oceanographic Institution (WHOI) and colleagues has found a marked change in the Indian Ocean's surface temperatures that puts southeast Australia on course for increasingly hot and dry conditions.
9h
Infographic: The Neurobiology of Suicidal Behavior
submitted by /u/smallpocketlibrary [link] [comments]
2h
Inherited arrhythmia in young Finnish Leonbergers under investigation
Inherited malignant ventricular arrhythmia is a fairly common disorder among Finnish Leonbergers under three years of age, with the most severe cases potentially resulting in sudden death. Researchers are striving to identify the gene mutation underlying the disorder.
10h
Injection strategies are crucial for geothermal projects
The fear of earthquakes is one of the main reasons for reservations about geothermal energy. In order to get hot water from the depths, crevices in the rock underground often have to be created. This is done by injecting large quantities of water under high pressure. The problem is that such hydraulic stimulation is accompanied by vibrations in the underground, known as "induced seismicity". A new
8h
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-14968-9 Non-canonical HLA-bound peptides from presumed non-coding regions are potential targets for cancer immunotherapy, but their discovery remains challenging. Here, the authors integrate exome sequencing, transcriptomics, ribosome profiling, and immunopeptidomics to identify tumor-specific non-canonical HLA-bound p
13h
Intel processors are still vulnerable to attack
Computer scientists at KU Leuven have once again exposed a security flaw in Intel processors. Jo Van Bulck, Frank Piessens, and their colleagues in Austria, the United States, and Australia gave the manufacturer one year's time to fix the problem.
6h
Interactions between changing climate and biodiversity: Shaping humanity's future [Commentaries]
Scientists have known for more than a century about potential human impacts on climate (1). In the last 30 y, estimates of these impacts have been confirmed and refined through increasingly precise climate assessments (2). Other global-scale human impacts, including land use change, overharvesting, air and water pollution, and increased…
6h
Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus [Immunology and Inflammation]
Type III IFN lambdas (IFN-λ) have recently been described as important mediators of immune responses at barrier surfaces. However, their role in autoimmune diseases such as systemic lupus erythematosus (SLE), a condition characterized by aberrant type I IFN signaling, has not been determined. Here, we identify a nonredundant role for…
7h
Intestinal bile acids directly modulate the structure and function of C. difficile TcdB toxin [Microbiology]
Intestinal bile acids are known to modulate the germination and growth of Clostridioides difficile. Here we describe a role for intestinal bile acids in directly binding and neutralizing TcdB toxin, the primary determinant of C. difficile disease. We show that individual primary and secondary bile acids reversibly bind and inhibit…
6h
Intralipid improves efficacy of chemotherapy treatment
Pairing chemotherapy nanodrugs with a nutritional supplement can lessen devastating side-effects while reducing the amount of the expensive drugs needed to treat cancer according to a study from Carnegie Mellon University and Taiwan's National Health Research Institutes. In addition, pretreatment with the supplement promotes the production of tumor-killing macrophages, making it a promising comple
9h
Intrinsically disordered protein RBM14 plays a role in generation of RNA:DNA hybrids at double-strand break sites [Cell Biology]
Accumulating evidence suggests participation of RNA-binding proteins with intrinsically disordered domains (IDPs) in the DNA damage response (DDR). These IDPs form liquid compartments at DNA damage sites in a poly(ADP ribose) (PAR)-dependent manner. However, it is greatly unknown how the IDPs are involved in DDR. We have shown previously that…
7h
Introducing the light-operated hard drives of tomorrow
What do you get when you place a thin film of perovkite material used in solar cells on top of a magnetic substrate? More efficient hard drive technology. EPFL physicist László Forró and his team pave the way for the future of data storage.
11h
Inverse design software automates design process for optical, nanophotonic structures
Stanford University researchers created an inverse design codebase called SPINS that can help researchers explore different design methodologies to find fabricable optical and nanophotonic structures. In the journal Applied Physics Reviews, Logan Su and colleagues review inverse design's potential for optical and nanophotonic structures, as well as present and explain how to use their own inverse
8h
Investigation underway: Inherited arrhythmia leading to sudden deaths in young Finnish Leonbergers
A new study in Finland has revealed that inherited malignant ventricular arrhythmia is fairly common among Finnish Leonbergers under three years of age. At its worst, such arrhythmia can result in the dog's sudden death.
9h
IPyA glucosylation mediates light and temperature signaling to regulate auxin-dependent hypocotyl elongation in Arabidopsis [Plant Biology]
Auxin is a class of plant hormone that plays a crucial role in the life cycle of plants, particularly in the growth response of plants to ever-changing environments. Since the auxin responses are concentration-dependent and higher auxin concentrations might often be inhibitory, the optimal endogenous auxin level must be closely…
6h
Is social media killing intellectual humility?
Social media echo chambers have made us overconfident in our knowledge and abilities. Social psychologists have shown that publicly committing to an opinion makes you less willing to change your mind. To avoid a descent into epistemic arrogance and tribalism, we need to use social media with deep humility. "Every liberal loves the figure of Socrates," Jonathan Rauch writes in his 1991 book Kindly
1d
Jack Dorsey's Reprieve as Twitter CEO May Not Last
Twitter Elliott Dorsey
A deal with activist investor Elliott Management preserves Dorsey's job. But it gives him—and Twitter—tough targets to meet this year.
14h
Johnson's majority slashed as 38 Tory rebels fire warning shot over Huawei's involvement in 5G – as it happened
MPs vote down Iain Duncan Smith's amendment by 306 votes to 282, cutting Boris Johnson's working majority of 87 Government majority cut as almost 40 Tories rebel over Huawei 5.45pm GMT Related: Coronavirus live updates: number of deaths outside China passes 1,000 as Italy records highest one-day toll 5.20pm GMT The official division list for the Huawei vote is now up. Some 38 Tory MPs actively re
6h
Joint profiling of chromatin accessibility and CAR-T integration site analysis at population and single-cell levels [Immunology and Inflammation]
Chimeric antigen receptor (CAR)-T immunotherapy has yielded impressive results in several B cell malignancies, establishing itself as a powerful means to redirect the natural properties of T lymphocytes. In this strategy, the T cell genome is modified by the integration of lentiviral vectors encoding CAR that direct tumor cell killing….
7h
Killer whale presence drives bowhead whale selection for sea ice in Arctic seascapes of fear [Ecology]
The effects of predator intimidation on habitat use and behavior of prey species are rarely quantified for large marine vertebrates over ecologically relevant scales. Using state space movement models followed by a series of step selection functions, we analyzed movement data of concurrently tracked prey, bowhead whales (Balaena mysticetus; n…
6h
Kommunerne køber færre og færre elbiler
PLUS. Selvom elbiler kan være et godt redskab til grøn omstilling i kommunerne, køber de færre og færre af dem. En mulig forklaring er et stop for støtteordninger og en nedprioritering af grøn transport.
20h
Land-atmosphere interaction and cloud-precipitation characteristics in Tibetan plateau
Land surface processes and summer cloud-precipitation characteristics in the Tibetan Plateau (TP) can impact downstream weather and climate changes. They are also the key to understand Asian monsoon system and atmospheric circulation changes in the Northern Hemisphere.
9h
Large study confirms diet linked to anxiety disorders
Ten percent of the global population currently suffers from an anxiety disorder. A Canadian-based team discovered a link between anxiety and high-sugar, processed foods. Subjects whose diets were high in fruits and vegetables were less likely to suffer from such a disorder. If there were ever a week in which anxiety disorders were peaking, this would be it. As if we needed the extra stress. Rough
5h
Leaf-inspired surface prevents frost formation
By tweaking the texture of any material's surface, researchers experimentally reduced frost formation by up to 60%. They theoretically predict they could reduce formation by up to 80%.
5h
Leaving your baby to 'cry it out' has no adverse effects on child development
Leaving an infant to 'cry it out' from birth up to 18 months does not adversely affect their behaviour development or attachment, researchers from the University of Warwick have found, they also discovered that those left to cry cried less and for a shorter duration at 18 months of age.
49min
Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine [Immunology and Inflammation]
A comprehensive understanding of the development and evolution of human B cell responses induced by pathogen exposure will facilitate the design of next-generation vaccines. Here, we utilized a high-throughput single B cell cloning technology to longitudinally track the human B cell response to the yellow fever virus 17D (YFV-17D) vaccine….
6h
Low-dose chest CT leaves DNA intact
The low-dose chest CT scans used in lung cancer screening do not appear to damage human DNA, according to a new study. The results could help allay fears that such screenings will lead to an increase in radiation-induced cancer.
9h
Lysosomal degradation products induce Coxiella burnetii virulence [Microbiology]
Coxiella burnetii is an intracellular pathogen that replicates in a lysosome-like vacuole through activation of a Dot/Icm-type IVB secretion system and subsequent translocation of effectors that remodel the host cell. Here a genome-wide small interfering RNA screen and reporter assay were used to identify host proteins required for Dot/Icm effector…
6h
Machine learning predicts circulatory failure hours in advance
A new method that uses machine learning to evaluate patient data in intensive care units can predict circulatory failure hours before it occurs, researchers report. Patients in a hospital's intensive care unit stay under close observation: clinicians continuously monitor their vital signs such as their pulse, blood pressure, and blood oxygen saturation. This furnishes doctors and nurses with a we
11h
Mad eller ad? Petra og Carolin redder de grimme grøntsager
For store, for modne, for skæve. Næsten hver tredje grøntsag er 'for grim' til supermarkederne.
12h
Madagascar's mysterious, lemur-eating cats started as ship stowaways
Ancestors of large forest cats likely hopped off Arabian trading ships more than a millennium ago
2h
Magic Act: Steamboats Make Wilderness Disappear
Originally published in March 1880 — Read more on ScientificAmerican.com
13h
Magnetic teeth revealed using quantum imaging
Biology provides us with a constant source of inspiration for designing and exploring new functional materials.
9h
Making more MXene: Researchers unveil a scalable production system for the promising, 2-D nanomaterials
For more than a decade, two-dimensional nanomaterials, such as graphene, have been touted as the key to making better microchips, batteries, antennas and many other devices. But a significant challenge of using these atom-thin building materials for the technology of the future is ensuring that they can be produced in bulk quantities without losing their quality. For one of the most promising new
8h
Male size advantage drives evolution of sex change in reef fish
Some species of fish, notably parrotfish and wrasses living on coral reefs, change their biological sex as they age, beginning life as females and later becoming functionally male. New work shows that this sequential hermaphroditism evolves when bigger males gain an advantage in reproductive success — for example by defending a permanent mating territory.
8h
Malnourished bugs: Higher carbon levels make plants less nutritious, hurting insect populations
Grasshopper populations, like those of many other insects, are declining. My colleagues and I identified a new possible culprit: The plants grasshoppers rely on for food are becoming less nutritious due to increased levels of carbon dioxide in the air.
10h
Mangrove conservation can pay for itself in flood protection
The natural coastal defenses provided by mangrove forests reduce annual flooding significantly in critical hotspots around the world. Without mangroves, flood damages would increase by more than $65 billion annually, and 15 million more people would be flooded, according to a new study.
9h
Massively parallel variant characterization identifies NUDT15 alleles associated with thiopurine toxicity [Genetics]
As a prototype of genomics-guided precision medicine, individualized thiopurine dosing based on pharmacogenetics is a highly effective way to mitigate hematopoietic toxicity of this class of drugs. Recently, NUDT15 deficiency was identified as a genetic cause of thiopurine toxicity, and NUDT15-informed preemptive dose reduction was quickly adopted in clinical settings….
7h
Mechanism of murderous mushrooms paves path for parasitic helminth halt [Commentaries]
"In the animal kingdom, the rule is, eat or be eaten" (ref. 1, p. 20). We will expand academic Thomas Szasz's statement to include the fungi, because in the multifaceted interactions of fungi and nematodes, this is often a steadfast rule. Indeed, soil systems that appear inert or lifeless to…
6h
Mechanistic approaches for chemically modifying the coordination sphere of copper-amyloid-{beta} complexes [Biochemistry]
Neurotoxic implications of the interactions between Cu(I/II) and amyloid-β (Aβ) indicate a connection between amyloid cascade hypothesis and metal ion hypothesis with respect to the neurodegeneration associated with Alzheimer's disease (AD). Herein, we report a mechanistic strategy for modifying the first coordination sphere of Cu(II) bound to Aβ utilizing a…
7h
Meet Carlo, an ancient reptile who had part of his face bitten off
A fossil of a predatory reptile from the dinosaur era is missing the front of its jaws, suggesting it was attacked by a rival that bit them off
17h
Meet LUVOIR, which might become one of NASA's next big space telescopes
submitted by /u/TheExoplanetsChannel [link] [comments]
13h
Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress [Genetics]
A more comprehensive understanding of the molecular mechanisms underlying pancreatic diseases, including pancreatitis and cancer, is essential to improve clinical management. MEN1 has established roles in epigenetic regulation and tumor suppression in the endocrine pancreas; however, intriguing recent data suggest MEN1 may also function in the exocrine pancreas. Using physiologically…
6h
Mennonites turned Paraguay into a mega beef producer: Now Indigenous people must pay the price
The "new Panama Canal"—that's how some are hailing a highway now under construction in South America that spans the continent, from the Atlantic to the Pacific.
9h
Method yields high rate of D-lactate using cyanobacteria, could revolutionize bioplastic production
A Kobe University led research team has illuminated the mechanism by which cyanobacteria (Synechocystis sp. PCC 6803) produces D-lactate, showing that malic enzyme facilitates this production. Subsequently, they succeeded in producing the world's highest rate (26.6g/L) of D-lactate directly from CO2 and light by modifying the D-lactate synthesis pathway using genetic engineering .
11h
Microplastics affect the survival of amphibians and invertebrates in river ecosystems
In collaboration with the National Museum of Natural Sciences (CSIC) in Madrid, the UPV/EHU's Stream Ecology research group has conducted two parallel studies to look at how the larvae of one freshwater amphibian and one invertebrate evolved during 15 days' exposure to microplastics at different concentrations. The highest concentrations used had lethal effects and the intermediate ones reduced th
8h
Mild depolarization of the inner mitochondrial membrane is a crucial component of an anti-aging program [Biochemistry]
The mitochondria of various tissues from mice, naked mole rats (NMRs), and bats possess two mechanistically similar systems to prevent the generation of mitochondrial reactive oxygen species (mROS): hexokinases I and II and creatine kinase bound to mitochondrial membranes. Both systems operate in a manner such that one of the…
6h
Mind Reading and Mind Control Technologies Are Coming
We need to figure out the ethical implications before they arrive — Read more on ScientificAmerican.com
13h
Mining gold from implicit models to improve likelihood-free inference [Statistics]
Simulators often provide the best description of real-world phenomena. However, the probability density that they implicitly define is often intractable, leading to challenging inverse problems for inference. Recently, a number of techniques have been introduced in which a surrogate for the intractable density is learned, including normalizing flows and density…
7h
Mitotic and pheromone-specific intrinsic polarization cues interfere with gradient sensing in Saccharomyces cerevisiae [Cell Biology]
Polarity decisions are central to many processes, including mitosis and chemotropism. In Saccharomyces cerevisiae, budding and mating projection (MP) formation use an overlapping system of cortical landmarks that converges on the small G protein Cdc42. However, pheromone-gradient sensing must override the Rsr1-dependent internal polarity cues used for budding. Using this…
6h
Modern virtual and augmented reality device can help simulate sight loss
Published today, during World Glaucoma Week 2020, a new study demonstrates how commercially available head mounted displays (HMD) can be used to simulate the day-to-day challenges faced by people with sight loss from glaucoma. The study, from the Crabb Lab, at City, University of London, suggests potential applications of the technology could include helping policymakers better assess the impact o
10h
Momentum-resolved superconducting energy gaps of Sr2RuO4 from quasiparticle interference imaging [Physics]
Sr2RuO4 has long been the focus of intense research interest because of conjectures that it is a correlated topological superconductor. It is the momentum space (k-space) structure of the superconducting energy gap Δi(k) on each band i that encodes its unknown superconducting order parameter. However, because the energy scales are…
7h
More choice means higher prices for American diabetics
Innovative drugs promise to make life easier — yet many people struggle to afford even insulin
19h
More than a nice coating
Researchers at the Netherlands Institute for Neuroscience (NIN) have shown that specialized aggregates of molecules enwrapping nerve cells in the brain, the perineuronal nets, are crucial for regulating the connections between nerve cells that control motor memories. The discovery, published in the PNAS, provide novel insight into how memories are formed and stored in the brain.
10h
More time visualizing an action improves your learning
Visualizing an action in the moments just before it takes place may influence learning, a new study suggests. We've all heard the saying: "Practice makes perfect." But the new research into the neurological process of learning how to move suggests that it might be more accurate to say "mindful practice makes perfect." This may not sound revolutionary to anyone who's ever shot a free throw like Le
8h
Most Medical Imaging Devices Run Outdated Operating Systems
The end of Windows 7 support has hit health care extra hard, leaving several machines vulnerable.
14h
Moving beyond the West vs. the rest: Understanding variation within Asian groups and its societal consequences [Psychological and Cognitive Sciences]
After decades of focusing almost exclusively on Western populations, psychology and other social sciences have at last begun to diversify their samples. Massive efforts have been made to compare cultures around the globe on basic psychological processes, and researchers have amassed much evidence for differences between "the West and the…
7h
MRI monitoring of energy storage in vivo using magnetization pathways [Medical Sciences]
Primary storage of energy in mammalian tissue is glycogen, a branched polysaccharide form of glucose. Glycogen serves a central role in glucose homeostasis and is crucial for proper system functioning. Altered glycogen metabolism is manifested in a variety of disorders such as diabetes, liver diseases, glycogen storage diseases, and cancer….
7h
Muscle stem cells compiled in 'atlas'
A team of Cornell researchers led by Ben Cosgrove, assistant professor in the Meinig School of Biomedical Engineering, used a new cellular profiling technology to probe and catalog the activity of almost every kind of cell involved in muscle repair. They compiled their findings into a 'cell atlas' of muscle regeneration that is one of the largest datasets of its kind.
8h
Music shows promise in decreasing delirium in critically ill patients
Mechanically ventilated ICU patients — more than a million adults annually in the US — are at increased risk for delirium, which is associated with prolonged ICU stays, higher healthcare costs and increased mortality. A study from Indiana University School of Medicine and Regenstrief Institute researchers reports that music appears to decrease delirium in ICU patients on mechanical ventilators.
9h
Människokroppen kan lösa upp guld
Metalliskt guld anses ju vara mycket motståndskraftigt mot kemisk påverkan, och har länge använts för olika medicinska ändamål i tron att det inte skulle lägga sig i människokroppens biokemiska processer. Men nyligen rapporterade Alice Balfourier och medarbetare i den amerikanska vetenskapsakademins tidskrift, att de s.k. lysosomerna i mänskliga celler kan lösa upp små guldpartiklar, troligen med
10h
Nanoscale precipitates as sustainable dislocation sources for enhanced ductility and high strength [Engineering]
Traditionally, precipitates in a material are thought to serve as obstacles to dislocation glide and cause hardening of the material. This conventional wisdom, however, fails to explain recent discoveries of ultrahigh-strength and large-ductility materials with a high density of nanoscale precipitates, as obstacles to dislocation glide often lead to high…
7h
NASA, South Korea, and the European Space Agency are working together on a "virtual constellation" of space-based instruments to document global air quality in unprecedented detail. For the first time, scientists will be able to track pollution from space on an hourly basis
submitted by /u/Wagamaga [link] [comments]
13h
NASA's Asteroid-Sampling Spacecraft Just Made The Closest Pass of Its Target Yet
Bennu, it's almost time.
17h
Natural contaminant threatens groundwater quality
Climate change and urbanisation drive the looming crisis.
8h
Necroptosis-blocking compound NBC1 targets heat shock protein 70 to inhibit MLKL polymerization and necroptosis [Biochemistry]
Necroptosis is a regulated necrotic cell death pathway involved in development and disease. Its signaling cascade results in the formation of disulfide bond-dependent amyloid-like polymers of mixed lineage kinase domain-like protein (MLKL), which mediate proinflammatory cell membrane disruption. We screened compound libraries provided by the National Cancer Institute and identified…
6h
Neonicotinoid and sulfoximine pesticides differentially impair insect escape behavior and motion detection [Neuroscience]
Insect nervous systems offer unique advantages for studying interactions between sensory systems and behavior, given their complexity with high tractability. By examining the neural coding of salient environmental stimuli and resulting behavioral output in the context of environmental stressors, we gain an understanding of the effects of these stressors on…
7h
Neuronal, stromal, and T-regulatory cell crosstalk in murine skeletal muscle [Immunology and Inflammation]
A distinct population of Foxp3+CD4+ regulatory T (Treg) cells promotes repair of acutely or chronically injured skeletal muscle. The accumulation of these cells depends critically on interleukin (IL)-33 produced by local mesenchymal stromal cells (mSCs). An intriguing physical association among muscle nerves, IL-33+ mSCs, and Tregs has been reported, and…
7h
Neurotransmitter map may lead to new drugs
A new map of a neurotransmitter may lead to better drugs for ADHD, depression, epilepsy, and more, researchers report. The discovery also adds to the researchers' knowledge of neurotransmitters in the brain. The map is of a new conformation of LeuT, a bacterial protein that belongs to the same family of proteins as the brain's neurotransmitter transporters. These transporters are special proteins
6h
Neutron star with measured at 11 kilometers radius
An international research team led by members of the Max Planck Institute for Gravitational Physics (Albert Einstein Institute; AEI) has obtained new measurements of how big neutron stars are. To do so, they combined a general first-principles description of the unknown behavior of neutron star matter with multi-messenger observations of the binary neutron star merger GW170817. Their results, whic
9h
New acoustic smart material inspired by shark skin
Researchers created a new sharkskin-inspired smart material that allows shifts in acoustic transmission on demand using magnets. As a result the new material can achieve multiple properties in one structure by switching between states, for example transmitting and also damping external noise transmission in a submarine through a single device. This smart material can recreate properties intrinsic
9h
New Character Test
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4h
New clinical trial examines a potential noninvasive solution for overactive bladders
Keck Medicine of USC urologists are launching a clinical trial to evaluate the effectiveness of spinal cord stimulation in patients with an overactive bladder due to neurological conditions, such as a spinal cord injury or stroke, and idiopathic (unknown) causes.
19h
New colony of rare freshwater pearl mussels found in Highlands
The species was uncovered during a watercourse survey being carried out in north Highland.
5h
New LHCb analysis still sees previous intriguing results
At a seminar today at CERN, the LHCb collaboration presented a new analysis of data from a specific transformation, or "decay," that a particle called B0 meson can undergo. The analysis is based on twice as many B0 decays as previous LHCb analyses, which had disclosed some tension with the Standard Model of particle physics. The tension is still present in the new analysis, but more data are neede
9h
New research finds infant cereal consumption is associated with improved nutrient intake
An investigation of infant feeding patterns found infants and toddlers consuming baby cereal, such as rice cereal, had higher intakes of key nutrients of concern, such as calcium, magnesium, iron, zinc and vitamin E. The study illustrates the importance of rice baby cereal in the diets of infants and toddlers in achieving proper nutrition.
8h
New research shows children and teens worry about political issues
A new psychological study suggests that children and teens are worried about political issues, though it's unclear that children's and teens' worry is a cause for concern, or that it is interfering with their mental health functioning.
10h
New study confirms value of family meals
A new study published in The Journal of Nutrition Education and Behavior (JNEB) builds on years of previous research studies and demonstrates the value of family meals. This study showed that more frequent family meals were associated with better dietary outcomes and family functioning outcomes. While Americans celebrate the month of March as National Nutrition Month, these findings underscore the
8h
New study identifies valuable tool for treating pancreatic cancer patients
Today, new research published in Annals of Surgery from the University of Colorado Department of Surgery at the Anschutz Medical Campus offers a roadmap to new guidelines for physicians in prioritizing treatments for pancreatic cancer and improving outcomes through surgery.
6h
New study presents ion concentrate electrolyte using solvent containing fluorine atoms
A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has unveiled an ion concentrate electrolyte using a solvent containing fluorine atoms.
19h
New study unveils the mechanism of DNA high-order structure formation
A joint research team led by Professor Ja Yil Lee (School of Life Sciences, UNIST) and Professor Ji-Joon Song (Department of Biological Sciences, KAIST) has unveiled the structure and mechanism of proteins that are highly overexpressed in cancers and associated with poor patient prognoses. The findings could speed up the discovery and development of new cancer drugs.
12h
New technique could elucidate earliest stages of planet's life
A new kind of astronomical observation helped reveal the possible evolutionary history of a baby Neptune-like exoplanet.
11h
New test is a better gauge of how much nitrogen corn needs
A new test that uses soil biology to measure how much nitrogen corn needs yields more accurate results than previous tests, researchers say. The soil fertility tests farmers have used for decades don't account for the vast majority of the nitrogen in soils. Nitrogen plays an essential role in plant growth, and farmers need to know how much nitrogen is present in their soil to optimize their appli
5h
New test measures corn nitrogen needs with greater accuracy
The soil fertility tests farmers have used for decades to measure nitrogen levels don't account for the vast majority of the nitrogen in soils, so Iowa State University scientists helped develop a new test that yields more accurate results by using soil biology.
11h
New York Is Using Prison Labor to Make Emergency Hand Sanitizer
100,000 Gallons New York governor Andrew Cuomo has an idea to tackle a hand sanitizer shortage, The New York Times reports : use prison labor to make more of the stuff. Cuomo has enlisted the help of Corcraft, New York's prison-based product company to produce about 100,000 gallons per week — a response, he said, spiking product prices . "You don't even have the floral bouquet," Cuomo said at a b
9h
Next generation water splitter could help renewables power the globe
Devices that forgo expensive metals could turn renewable electricity into hydrogen
4h
NIST study uncovers a potential driver of premature solar panel failures
Manufacturers typically guarantee that solar panels will make it past their 25th birthday, however, recent reports indicate that the protective backsheets of many are cracking decades early. The source of their rapid degradation has been unclear but new research from NIST may offer answers that could support the development of longer-lived panels.
5h
Nitrogen pollution interacts with heat stress to increase coral bleaching across the seascape [Ecology]
Climate change is increasing the frequency and magnitude of temperature anomalies that cause coral bleaching, leading to widespread mortality of stony corals that can fundamentally alter reef structure and function. However, bleaching often is spatially variable for a given heat stress event, and drivers of this heterogeneity are not well…
7h
No evidence of suitability of prophylactic fluids for wildfire prevention at landscape scales [Physical Sciences]
Yu et al. (1) propose a viscoelastic fluid as a prophylactic fire-retardant treatment in landscapes at high risk of wildfires. We argue that, while the idea is worth exploring further, their data do not support its suitability for real landscape-scale applications. First, they report their fluid is environmentally benign because…
7h
Noncitizens are undertreated for heart attack, stroke risk factors
A new study published in Circulation, a journal of the American Heart Association, shows that noncitizens in the United States are less likely to receive treatment for cardiovascular disease risk factors when compared with born or naturalized US citizens.
14h
Non-thermal plasma can inactivate airborne viral threat to pigs
One of the most costly diseases facing the pork industry is caused by a virus that new research shows can be rendered harmless in a fraction of a second by a cold plasma reactor developed at the University of Michigan.
9h
Norway wants to successfully complete its first fully electric domestic flight by 2030. By 2040, it wants all civil domestic aviation in Norway to be electric. If this pans out, it says greenhouse gas emissions will be cut by 80% compared with 2020.
submitted by /u/ngt_ [link] [comments]
13h
Not a Tempest in a Teapot
When NASA climate scientists speak in public, they're often asked about possible connections between climate change and extreme weather events such as hurricanes, heavy downpours, floods, blizzards, heat waves and droughts. After all, it seems extreme weather is in the news almost every day of late, and people are taking notice. How might particular extreme weather and natural climate phenomena,
9h
Novel blood test points to risk of weight gain and diabetes
The blood test method makes use of machine learning and can be used to predict whether patients will put on weight, unless they change their habits. The project was conducted in Brazil with funding from FAPESP.
7h
NREL research boosts stability of perovskites, helps silicon solar cells
A change in chemical composition enabled scientists to boost the longevity and efficiency of a perovskite solar cell developed at the U.S. Department of Energy's (DOE's) National Renewable Energy Laboratory (NREL).
8h
NUS study reveals positive connection between nature experiences and happiness globally
An AI analysis of photographs posted on social media revealed a positive association between nature and happiness globally.
10h
Nutrient dilution and climate cycles underlie declines in a dominant insect herbivore [Ecology]
Evidence for global insect declines mounts, increasing our need to understand underlying mechanisms. We test the nutrient dilution (ND) hypothesis—the decreasing concentration of essential dietary minerals with increasing plant productivity—that particularly targets insect herbivores. Nutrient dilution can result from increased plant biomass due to climate or CO2 enrichment. Additionally, when…
6h
Nye tal: Langt de fleste udvikler symptomer inden for 11,5 dage
Tallene bekræfter, at en karantæneperiode på 14 dage er sikker, siger ekspert.
18h
När läraren planerat bra lär sig eleverna bättre
Hur lärare planerar lektioner kan ha stor betydelse för hur eleverna lär sig. I en ny avhandling har olika sätt att planera lektioner för att lära ut det matematiska begreppet derivata testats. – Lärares olika sätt att behandla innehållet leder till olika sorts lärande hos eleverna. Det kan låta självklart. Men oftast har läraren ingen exakt koll på vad eleverna lär sig under en lektion. Det är f
10h
Observation of dissipative chlorophyll-to-carotenoid energy transfer in light-harvesting complex II in membrane nanodiscs
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-15074-6 Resolving the kinetics of energy dissipation during photosynthesis is challenging due to complex photophysics and the coexistence of multiple antenna proteins. Here Son et al. overcome this by applying ultrabroadband 2D spectroscopy to LHCII reconstituted in lipid nanodiscs, revealing mechanisms of dissipation
13h
Observed: An occultation of a brown dwarf by another
An international team of astronomers in the project SPECULOOS, dedicated to the search for habitable planets, with scientists participating from the Instituto de Astrofísica de Canarias (IAC) has discovered an eclipse (termed an occultation) in a peculiar brown dwarf formed by two stars orbiting around each other. The results are just published in the journal Nature Astronomy.
9h
Older women with breast cancer may benefit from genetic testing, study suggests
About 1 in 40 postmenopausal women diagnosed with breast cancer before age 65 have cancer-associated mutations in their BRCA1 or BRCA2 genes, according to a Stanford-led study of more than 4,500 participants in the long-running Women's Health Initiative.
8h
On the Way to the Radically Superintelligent Civilization: Why Is It Important to Implement UBI?
submitted by /u/EcstadelicNET [link] [comments]
13h
Online shoppers swayed by customer reviews of physical products—not experiences
Amazon Walk Out Retailers
We live in a world of online reviews. Before spending on everything from restaurant meals to a new pair of jeans or even a European vacation, many of us often check Amazon, Yelp or TripAdvisor first.
10h
Opening of smaller toxin pores by lipid micelle formation [Biological Sciences]
While pore-forming toxins (PFTs) are a large class of molecular weapons employed by organisms across the animal kingdom (1), notably, pathogenic bacteria, many mechanistic steps of pore formation in target membranes are unknown. In PNAS, using molecular dynamics (MD) simulations, Vӧgele et al. (2) observed how central lipids corresponding to…
7h
Optofluidic control of rodent learning using cloaked caged glutamate [Chemistry]
Glutamate is the major excitatory neurotransmitter in the brain, and photochemical release of glutamate (or uncaging) is a chemical technique widely used by biologists to interrogate its physiology. A basic prerequisite of these optical probes is bio-inertness before photolysis. However, all caged glutamates are known to have strong antagonism toward…
6h
Ostrich eggshell bead strontium isotopes reveal persistent macroscale social networking across late Quaternary southern Africa [Anthropology]
Hunter-gatherer exchange networks dampen subsistence and reproductive risks by building relationships of mutual support outside local groups that are underwritten by symbolic gift exchange. Hxaro, the system of delayed reciprocity between Ju/'hoãn individuals in southern Africa's Kalahari Desert, is the best-known such example and the basis for most analogies and…
6h
Our brains are powerful — but secretive — forecasters of video virality
Our brains can predict the popularity of online videos, without us even knowing it.
8h
Our Intimacy with Technology May Enhance Humanity
Many scholars now think we're entering into a dehumanizing "artificial intimacy" with gadgets, algorithms, and interfaces. But our bonds with technology may actually have roots in an ancient and natural tendency called animism, which exists to hone our empathetic skills for real human bonding.
15h
Pain researchers get a common language to describe pain
Pain researchers around the world have agreed to classify pain in the mouth, jaw and face according to the same system. According to a participant from Aarhus University in Denmark, this means more precise diagnoses and improved treatment of people suffering from pain.
8h
Paleontologists discover solid evidence of formerly elusive abrupt sea-level jump
Meltwater pulses (MWPs) known as abrupt sea-level rise will inevitably affect cities especially those on coastal plains of low elevation. A recent study presented evidence of abrupt sea level change between 11,300-11,000 years ago in the Arctic Ocean, solving the puzzle of second largest meltwater pulse (labelled as "MWP-1B" next to the largest and already well understood MWP-1A).
9h
Palm oil must be made more sustainable while replacements are made scalable, engineers warn
Efforts to create synthetic replacements for palm oil are still likely to take several years, so immediate attention should be focused on making the existing production process more sustainable, researchers at the University of Bath's Centre for Integrated Bioprocessing Research (CIBR) and Centre for Sustainable Circular Technologies (CSCT) have found.
8h
Paper sheds light on infant universe and origin of matter
A new study of the QCD axion, conducted to better understand the origin of the universe, has provided insight into some of the most enduring questions in fundamental physics.
9h
Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers [Applied Biological Sciences]
We sought to define the landscape of alternative pre-mRNA splicing in prostate cancers and the relationship of exon choice to known cancer driver alterations. To do so, we compiled a metadataset composed of 876 RNA-sequencing (RNA-Seq) samples from five publicly available sources representing a range of prostate phenotypes from normal…
7h
Pentagon awards contracts to design mobile nuclear reactor
submitted by /u/Metlman13 [link] [comments]
13h
Photoperiod and temperature separately regulate nymphal development through JH and insulin/TOR signaling pathways in an insect [Physiology]
Insects living in the temperate zone enter a physiological state of arrested or slowed development to overcome an adverse season, such as winter. Developmental arrest, called diapause, occurs at a species-specific developmental stage, and embryonic and pupal diapauses have been extensively studied in mostly holometabolous insects. Some other insects overwinter…
7h
Physicists keep improving 'smart' composites for biomedical sensors
IKBFU Physicists have successfully tested the new magnetic micro wire-based concept of "smart" composites production. The new composites are related to the multiferroic-class materials which have mutually controlled magnetic and electric properties. The effects observed in the compositions are considered to be a perspective platform for creating new devices from energy converters to highly sensiti
10h
Pinching a glass reveals key properties of its soft spots [Physics]
It is now well established that glasses feature quasilocalized nonphononic excitations—coined "soft spots"—, which follow a universal ω4 density of states in the limit of low frequencies ω. All glass-specific properties, such as the dependence on the preparation protocol or composition, are encapsulated in the nonuniversal prefactor of the universal…
7h
Poor countries struggle to get the insulin they need
High prices and patchy supplies make life hard for diabetics in the developing world
19h
Possible treatment for breast cancer patients could roll out to clinical trial immediately
A worldwide collaborative study involving scientists at the University of Sussex has proposed a new treatment strategy for patients with a rare but aggressive subtype of cancer known as triple negative breast cancer.
7h
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes [Biochemistry]
Anti-CRISPRs (Acrs) are small proteins that inhibit the RNA-guided DNA targeting activity of CRISPR-Cas enzymes. Encoded by bacteriophage and phage-derived bacterial genes, Acrs prevent CRISPR-mediated inhibition of phage infection and can also block CRISPR-Cas-mediated genome editing in eukaryotic cells. To identify Acrs capable of inhibiting Staphylococcus aureus Cas9 (SauCas9), an…
6h
Potential for release of pulmonary toxic ketene from vaping pyrolysis of vitamin E acetate [Chemistry]
A combined analytical, theoretical, and experimental study has shown that the vaping of vitamin E acetate has the potential to produce exceptionally toxic ketene gas, which may be a contributing factor to the upsurge in pulmonary injuries associated with using e-cigarette/vaping products. Additionally, the pyrolysis of vitamin E acetate also…
6h
Predicting appropriate opioid prescriptions post-cesarean delivery
Knowing the amount of opioids taken following cesarean section surgery and before discharge can inform individualized prescriptions and cut down on unnecessary, leftover pills that could be used for non-medical purposes, according to a new study from the University of Colorado Anschutz Medical Campus.
1d
Predicting the president: Two ways election forecasts are misunderstood
There are two common misconceptions that muddy people's understanding of election forecasting, says Eric Siegel: Blaming the prognosticator and predicting candidates versus predicting voters. In 2016, Nate Silver's forecast put about 70% odds on Clinton winning. Despite people's shock at the election results, that forecast was not wrong. As predictions for the 2020 presidential election ramp up,
3h
Probing the Possibilities of Ergodicity in the 1D Spin-1/2 XY Chain with Quench Dynamics
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61037-8
13h
PRR proteins of the circadian clock call time on shade avoidance [Plant Biology]
Light limitation represents a significant threat to plant survival. Shade-intolerant species have, therefore, evolved mechanisms to detect and avoid shading by neighbors. Plants detect the proximity and density of neighboring vegetation by monitoring alterations in light quality (1). Phytochrome photoreceptors detect changes in the ratio of red (R) to far-red…
7h
Publisher Correction: Population reference and healthy standard blood pressure range charts in pregnancy: findings from the Born in Bradford cohort study
Scientific Reports, Published online: 11 March 2020; doi:10.1038/s41598-020-61787-5
58min
Publisher Correction: Research on oral microbiota of monozygotic twins with discordant caries experience – in vitro and in vivo study
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61785-7
1d
Publisher Correction: Resolving the positions of defects in superconducting quantum bits
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61788-4
1d
Publisher Correction: Signatures of self-organized criticality in an ultracold atomic gas
Nature, Published online: 11 March 2020; doi:10.1038/s41586-020-2091-5
42min
Publishing in English Presents Challenges for International Authors
When submitting manuscripts to Western journals, authors face issues that go beyond language barriers.
2h
Quantifying snowfall from orographic cloud seeding [Earth, Atmospheric, and Planetary Sciences]
Climate change and population growth have increased demand for water in arid regions. For over half a century, cloud seeding has been evaluated as a technology to increase water supply; statistical approaches have compared seeded to nonseeded events through precipitation gauge analyses. Here, a physically based approach to quantify snowfall…
7h
Radiative absorption enhancements by black carbon controlled by particle-to-particle heterogeneity in composition [Earth, Atmospheric, and Planetary Sciences]
Black carbon (BC) absorbs solar radiation, leading to a strong but uncertain warming effect on climate. A key challenge in modeling and quantifying BC's radiative effect on climate is predicting enhancements in light absorption that result from internal mixing between BC and other aerosol components. Modeling and laboratory studies show…
7h
Radio galaxy NGC 3894 investigated with Fermi
Using the Large Area Telescope (LAT) onboard NASA's Fermi spacecraft, astronomers have investigated a nearby radio galaxy known as NGC 3894. Results of the study, presented in a paper published March 3, confirm the galaxy's young age and provide more insights into its properties.
11h
Regulation of Cullin-RING E3 ligase dynamics by Inositol hexakisphosphate [Commentaries]
Perhaps in a decade or so, researchers may look back on current times and view it as an inflection point for the development of novel therapeutic modalities for the treatment of various human diseases. One particularly innovative approach involves targeting disease-modifying proteins for degradation by the proteasome, the large multisubunit…
6h
Reply to Desikan et al.: Micelle formation among various mechanisms of toxin pore formation [Biological Sciences]
Pore-forming toxins (PFTs) are a diverse class of membrane-active proteins employed primarily by bacteria for unregulated perforation of lipid membranes (1). Based on molecular dynamics (MD) simulations (2), electron cryo-microscopy (cryoEM) structures (3), and atomic force microscopy (AFM) experiments (4), we recently identified two distinct pathways for lipid efflux from…
7h
Reply to Geiger and Stomper: On capital intensity and observed increases in the economic damages of extreme natural disasters [Letters (Online Only)]
We thank Geiger and Stomper (1) for the opportunity to clarify and further test the robustness of the results in Coronese et al. (2). Their comments reveal misinterpretations of our study and propose an alternative (but untested) hypothesis. Here we redress these misinterpretations and test their hypothesis. Geiger and Stomper…
6h
Representation of distinct reward variables for self and other in primate lateral hypothalamus [Neuroscience]
The lateral hypothalamus (LH) has long been implicated in maintaining behavioral homeostasis essential for the survival of an individual. However, recent evidence suggests its more widespread roles in behavioral coordination, extending to the social domain. The neuronal and circuit mechanisms behind the LH processing of social information are unknown. Here,…
7h
Research on soldier ants reveals that evolution can go in reverse
Turtle ant soldiers look like real-life creatures straight out of a Japanese anime film. These tree-dwelling insects scuttle to and fro sporting shiny, adorably oversized heads, which they use to block the entrances of their nests—essentially acting as living doors.
1d
Research shows mangrove conservation can pay for itself in flood protection
The natural coastal defenses provided by mangrove forests reduce annual flooding significantly in critical hotspots around the world. Without mangroves, flood damages would increase by more than $65 billion annually, and 15 million more people would be flooded, according to a new study published March 10, 2020 in Scientific Reports.
13h
Researchers create a new acoustic smart material inspired by shark skin
USC researchers created a new sharkskin-inspired smart material that allows shifts in acoustic transmission on demand using magnets. As a result the new material can achieve multiple properties in one structure by switching between states, for example transmitting and also damping external noise transmission in a submarine through a single device. This smart material can recreate properties intrin
11h
Researchers from US and Brazil develop a technique to quickly and sensitively characterize defects in 2-D materials (such as graphene).
submitted by /u/dannylenwinn [link] [comments]
13h
Researchers solve mystery of Tuvan throat singing
An international research team has uncoupled the mystery of how Tuvan throat singers produce distinctive sounds in which you can hear two different pitches at once—a low rumble and a high whistle-like tone.
9h
Researchers use microwaves to measure signs of dehydration
London and the National Physical Laboratory (NPL) has successfully used microwaves to measure blood-based molecules known to be influenced by dehydration.
10h
Residents Rallied to Measure Radiation After Fukushima. Nine Years Later, Many Scientists Still Ignore Their Data
A citizen scientist group now has thousands of radiation monitoring devices all around the world. But nuclear researchers are often reluctant to use the measurements.
2h
Ringmärkning behövs – trots ny teknik
Satellitsändare och så kallade ljusloggar kan ge allt mer information om fåglars liv. Har ringmärkningen spelat ut sin roll? − Nej, ringmärkning ger en hel del annan information som vi inte får med den nya tekniken, säger Thord Fransson på Ringmärkningscentralen vid Naturhistoriska riksmuseet.
16h
Rising economic damages of natural disasters: Trends in event intensity or capital intensity? [Letters (Online Only)]
The recent paper by Coronese et al. (1) reports a rise in economic damages due to extreme natural disasters reported in the Emergency Events Database (EM-DAT) (2). While Coronese et al.'s (1) paper is timely and relevant, we have serious concerns regarding the analysis and the interpretation of the results….
6h
Robotic feelings?
Artificial intelligence that shows vulnerability makes for better human conversation and experience.
8h
Robots that admit mistakes foster better conversation in humans
A new study showed that the humans on teams that included a robot expressing vulnerability communicated more with each other and later reported having a more positive group experience than people teamed with silent robots or with robots that made neutral statements, like reciting the game's score.
8h
Routine childhood vaccination linked to improved schooling among adults in India
In this study, researchers analyzed levels of schooling attainment in years among adults born during or after the implementation of India's Universal Immunization Programme (UIP) (intervention) compared to adults born before the implementation (control). District-level data from the rollout of India's UIP between 1985 and 1990 was matched to schooling data from the National Family Health Survey of
9h
Safeguarding intestine cells against enteropathogenic Escherichia coli by intracellular protein reaction, a preventive antibacterial mechanism [Chemistry]
A critical problem in the fight against bacterial infection is the rising rates of resistance and the lack of new antibiotics. The discovery of new targets or new antibacterial mechanisms is a potential solution but is becoming more difficult. Here we report an antibacterial mechanism that safeguards intestine cells from…
7h
Scientists Discover "Peculiar" Teardrop-Shaped Star
A team of astronomers have discovered a strange star that oscillates in a rhythmic pattern — but only on one side, causing gravitational forces to distort it into a teardrop shape. "We've known theoretically that stars like this should exist since the 1980s," said professor Don Kurtz from the University of Central Lancashire and co-author of the paper published in Nature Astronomy on Monday, in a
8h
Scientists find Earth and moon not identical oxygen twins
Scientists have found that the Earth and moon have distinct oxygen compositions and are not identical in oxygen as previously thought according to a new study.
52min
Scientists Linked Artificial and Biological Neurons in a Network—and Amazingly, It Worked
Scientists have linked up two silicon-based artificial neurons with a biological one across multiple countries into a fully-functional network. Using standard internet protocols, they established a chain of communication whereby an artificial neuron controls a living, biological one, and passes on the info to another artificial one. Whoa. We've talked plenty about brain-computer interfaces and no
10h
Scientists propose a flexible interface design for silicon-graphite dual-ion battery
A research group led by Prof. TANG Yongbing and his team members (Dr. JIANG Chunlei, XIANG Lei, MIAO Shijie etc.) from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences, along with Prof. ZHENG Zijian from the Hong Kong Polytechnic University, have proposed a flexible interface design to reduce alloying stress on silicon anodes in silicon-graphite DIBs.
10h
Scientists propose new method for large-scale production of thermally stable single-atom catalysts
A research group led by Prof. Qiao Botao from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences has proposed a new method for large-scale production of thermally stable single-atom catalysts (SACs) with high metal loading. Their findings were published in Nature Communications on Mar. 9.
12h
Scientists pursue two routes to remaking a pancreas
Advances in transplantation and medical electronics offer hope to people with type-1 diabetes
19h
Scientists shrink fin-width of FinFET to nearly the physical limit
FinFETs are known to be an evolution of metal-oxide-semiconductor field effect transistors (MOSFETs) featuring a semiconducting channel vertically wrapped by conformal gate electrodes. It was first proposed in 1990s in order to avoid the short channel effect and other drawbacks resulted from the shrinking of transistor size. Because of the limitation of nanofabrication, the minimum fin width is ab
10h
Searching For Atlantis | Rob Riggle: Global Investigator
For centuries, experts and archeologists have tried to pinpoint the lost city of Atlantis, but all have failed. Now Rob Riggle is on the case, and Atlantis has nowhere left to hide. Stream Full Episodes of Rob Riggle: Global Investigator: https://go.discovery.com/tv-shows/rob-riggle-global-investigator/ Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Join us on Facebook: https://www.face
7h
Self-help groups empower caregivers of children with disabilities
Caregivers in low-income settings will be able to respond to the challenges of bringing up children with disabilities, thanks to a new model created by the University of East Anglia (UEA) and the Kenya Medical Research Institute (KEMRI).
9h
Sensory information underpins abstract knowledge
What we learn through our senses drives how knowledge is sorted in our brains, according to new research.
8h
Serum microRNA in patients undergoing atrial fibrillation ablation
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-61322-6
13h
Seven apps that make it much easier to work remotely
Many hands make light work. (Perry Grone/Unsplash/) The internet has transformed the way we live and communicate with each other, which means it's likely you have colleagues and clients spread across the world. With the right phone apps, you can make sure this geographical diversity doesn't hurt productivity, and ensure that everyone on your team is on the same page (sometimes literally). These c
7h
Short and simple sequences favored the emergence of N-helix phospho-ligand binding sites in the first enzymes [Biophysics and Computational Biology]
The ubiquity of phospho-ligands suggests that phosphate binding emerged at the earliest stage of protein evolution. To evaluate this hypothesis and unravel its details, we identified all phosphate-binding protein lineages in the Evolutionary Classification of Protein Domains database. We found at least 250 independent evolutionary lineages that bind small molecule…
7h
Sitting, squatting, and the evolutionary biology of human inactivity [Anthropology]
Recent work suggests human physiology is not well adapted to prolonged periods of inactivity, with time spent sitting increasing cardiovascular disease and mortality risk. Health risks from sitting are generally linked with reduced levels of muscle contractions in chair-sitting postures and associated reductions in muscle metabolism. These inactivity-associated health risks…
6h
Sleep-dependent memory consolidation in infants protects new episodic memories from existing semantic memories
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-14850-8 In infants, superiority of semantic over episodic memory formation has been postulated. Here, authors show that both types of memory coexist in one-year-olds, with consolidation during sleep affecting whether an experienced event is recognized as a detailed episode or as general semantic knowledge.
13h
Slime mold simulations used to map dark matter holding universe together
The behavior of one of nature's humblest creatures is helping astronomers probe the largest structures in the universe. There is an uncanny resemblance between the networks single-cell slime molds create to seek food and the vast cobweb structure of filaments gravity builds to tie galaxies and clusters of galaxies together.
6h
Small but powerful air purifiers
Cleaner air, everywhere. (Depositphotos/) Managing the air quality in your home or workplace is important, and you should be able to do so without an eyesore air purifier the size of a piece of furniture. There are compact and powerful air purifiers on the market that can get the job done without crowding your space. Many of them are even portable, so you can bring them with you as you move throu
1d
Solved: The mystery of the expansion of the universe
The Earth, solar system, the entire Milky Way and the few thousand galaxies closest to us move in a vast "bubble" that is 250 million light years in diameter, where the average density of matter is half as high as for the rest of the universe. This is the hypothesis advanced by a theoretical physicist from the University of Geneva (UNIGE) to solve a conundrum that has been splitting the scientific
11h
Some domesticated plants ignore beneficial soil microbes
A review by biologists at UC Riverside and Washington State University, Vancouver finds that plant domestication has often had a negative effect on plant microbiomes, making domesticated plants more dependent on fertilizer and other soil amendments than their wild relatives. To make crops more productive and sustainable, the authors recommend reintroduction of genes from the wild relatives of comm
5h
Space radar movies track motion on Earth's surface
Finnish satellite operator Iceye makes movies of activity on the ground through cloud and at night.
14h
SpaceX President: We Plan to Launch a Crewed Mission in May
May Happen SpaceX president Gwynne Shotwell says the company plans to launch a crewed mission in its Crew Dragon spacecraft sometime in May — just two months away — according to Reuters space reporter Joey Roulette. SpaceX president Gwynne Shotwell: We're looking at a May timeframe to launch crew for the first time on Crew Dragon. — Joey Roulette (@joroulette) March 10, 2020 Announcement Season S
4h
Spatiotemporal gating of SIRT1 functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia [Physiology]
Inefficient physiological transitions are known to cause metabolic disorders. Therefore, investigating mechanisms that constitute molecular switches in a central metabolic organ like the liver becomes crucial. Specifically, upstream mechanisms that control temporal engagement of transcription factors, which are essential to mediate physiological fed–fast–refed transitions are less understood. SIRT
6h
Splice variant of growth hormone-releasing hormone receptor drives esophageal squamous cell carcinoma conferring a therapeutic target [Medical Sciences]
The extrahypothalamic growth hormone-releasing hormone (GHRH) and its cognate receptors (GHRH-Rs) and splice variants are expressed in a variety of cancers. It has been shown that the pituitary type of GHRH-R (pGHRH-R) mediates the inhibition of tumor growth induced by GHRH-R antagonists. However, GHRH-R antagonists can also suppress some cancers…
6h
STAT3 signaling in myeloid cells promotes pathogenic myelin-specific T cell differentiation and autoimmune demyelination [Immunology and Inflammation]
Multiple sclerosis (MS) is an autoimmune inflammatory demyelinating disease of the central nervous system. Dysregulation of STAT3, a transcription factor pivotal to various cellular processes including Th17 cell differentiation, has been implicated in MS. Here, we report that STAT3 is activated in infiltrating monocytic cells near active MS lesions and…
7h
Stop Using Cleaning Products That Damage Your Health and the Environment
Everybody wants a clean house that is free of dirt, grime, and germs. Unfortunately, the vast majority of conventional household cleaning products contain excessively noxious chemicals and are packaged in single use plastic bottles. That means they are terrible for not just for our health, but for the environment, as well. However, there are a few companies out there working hard to change all th
8h
Strong selective effects of mitochondrial DNA on the nuclear genome [Evolution]
Oxidative phosphorylation, the primary source of cellular energy in eukaryotes, requires gene products encoded in both the nuclear and mitochondrial genomes. As a result, functional integration between the genomes is essential for efficient adenosine triphosphate (ATP) generation. Although within populations this integration is presumably maintained by coevolution, the importance of…
6h
Structural and mechanistic insights into secretagogin-mediated exocytosis [Biophysics and Computational Biology]
Secretagogin (SCGN) is a hexa–EF-hand protein that is highly expressed in the pancreas, brain, and gastrointestinal tract. SCGN is known to modulate regulated exocytosis in multiple cell lines and tissues; however, its exact functions and underlying mechanisms remain unclear. Here, we report that SCGN interacts with the plasma membrane SNARE…
6h
Study demonstrates how to collect true incidents from head impact sensors in youth sports
A new study from Children's Hospital of Philadelphia (CHOP) shows that head impact sensors can record a large number of false positive impacts during real game play. The CHOP team's study emphasizes that an extra step to video-confirm the sensor data is essential for research and for use of this data in injury prevention strategies for player safety.
19h
Study reveals a mechanism that plants can use to dissipate excess sunlight as heat
For plants, sunlight can be a double-edged sword. They need it to drive photosynthesis, the process that allows them to store solar energy as sugar molecules, but too much sun can dehydrate and damage their leaves.
14h
Study reveals collective dynamics of active matter systems
Flocks of starlings that produce dazzling patterns across the sky are natural examples of active matter—groups of individual agents coming together to create collective dynamics. In a study featured on the cover of the March 6 issue of the journal Science, a team of researchers that includes Brown University physicists reveals new insights into what happens inside active matter systems.
1d
Study reveals positive connection between nature experiences and happiness globally
The economic and ecological impact of nature on humans have long been established with prevalent environmental issues such as climate change and over-exploitation of natural resources being the first to cross one's mind. On the other hand, much less attention has been paid to the cultural and social values nature brings to humans. Even though natural wonders such as the Great Barrier Reef and the
8h
Study reveals rising colorectal cancer rates among young adults
A population-based analysis from England indicates that the incidence of colorectal cancer is increasing rapidly in young adults. The findings, which are published in BJS (British Journal of Surgery), suggest that colorectal cancer should no longer be considered a disease of older people.
10h
Study shows CRISPR effectiveness against colitis pathogen
Research at North Carolina State University shows that the CRISPR-Cas system can be used to effectively target and eliminate specific gut bacteria, in this case Clostridioides difficile, the pathogen that causes colitis — a chronic, degenerative disease of the colon. In a proof-of-concept study published in the journal mBio, researchers were able to show pathogen reductions in experiments conduct
7h
Study shows how contact with law enforcement, even for family members, decreases political participation
Research has long shown that people who spend time in jail or have high levels of contact with law enforcement are less likely to be politically engaged. University of Kansas researcher Brandon Davis has published a study detailing what types of contact influence participation. He found that network contacts, such as having a family member incarcerated, had a greater negative influence on feelings
9h
Study suggests Earth and Moon not identical oxygen twins
Scientists at The University of New Mexico have found that the Earth and Moon have distinct oxygen compositions and are not identical in oxygen as previously thought according to a new study released today in Nature Geoscience.
4h
Study ties kin selection to host-manipulating behavior in parasites
New research by Texas A&M University biologist Dr. Charles Criscione and collaborators in Canada shows that family ties and traits such as manipulation, sacrifice and selflessness are just as key to survival in parasitic organisms as they are in cognitive species like humans. In essence, when it comes to successful transmission, some parasites get by with a little help from their kin.
4h
Study: Daily avocado consumption improves attention in persons with overweight, obesity
A diet including daily avocado consumption improves the ability to focus attention in adults whose measurements of height and weight are categorized as overweight or obese, a new randomized control trial found. Researchers at the University of Illinois at Urbana-Champaign conducted the 12-week study.
7h
Submit to ESSLLI student session!
submitted by /u/ESSLLIStuS2020 [link] [comments]
2h
Svårt för liv att uppstå på Saturnus måne
Finns det liv utanför jorden? Vad behövs för att liv ska kunna uppstå och överleva? Astrobiologer letar efter svar bland annat på månarna kring solsystemets jätteplaneter. Saturnus måne Titan har hav på ytan och en tjock atmosfär, precis som jorden. Men på Titan består haven av flytande metan. Det är mycket kallt, omkring –180 grader Celsius, men ändå bjuder den speciella miljön på mycket komplex
15h
Tankelyn: Ny podcast går i kødet på tidens største dilemmaer
I Københavns Universitets nye podcast møder de skarpeste hjerner verdens største udfordringer….
18h
Teen bootleggers are making dangerous booze on TikTok
It may shock you to learn that brewing alcohol in your dorm room is not a great idea. (Pexels/) In the latest concerning TikTok trend , teens have documented their DIY alcohol adventures while brewing booze with grocery store ingredients—usually fruit juice, sugar, and active dry yeast. Some videos have racked up hundreds of thousands of likes and inspired others to establish their own bedroom mi
6h
The aging skin microenvironment dictates stem cell behavior [Developmental Biology]
Aging manifests with architectural alteration and functional decline of multiple organs throughout an organism. In mammals, aged skin is accompanied by a marked reduction in hair cycling and appearance of bald patches, leading researchers to propose that hair follicle stem cells (HFSCs) are either lost, differentiate, or change to an…
7h
The ATAD2/ANCCA homolog Yta7 cooperates with Scm3HJURP to deposit Cse4CENP-A at the centromere in yeast [Genetics]
The AAA+ ATPase and bromodomain factor ATAD2/ANCCA is overexpressed in many types of cancer, but how it contributes to tumorigenesis is not understood. Here, we report that the Saccharomyces cerevisiae homolog Yta7ATAD2 is a deposition factor for the centromeric histone H3 variant Cse4CENP-A at the centromere in yeast. Yta7ATAD2 regulates…
7h
The axion solves three mysteries of the universe
A hypothetical particle called the axion could solve one of physics' great mysteries: the excess of matter over antimatter, or why we're here at all.
6h
The best, proven way to make your leather boots last
Properly caring for your leather boots can add years of life. (Steve Johnson/) This story originally feature on Field & Stream . If you're one of those people who's ever found the perfect pair of leather boots, you know how important it can be to enjoy every minute of your time in them. Your favorite shoes are like an old friend—even if you haven't seen them for a while, you can take up right whe
2h
The countries building miniature nuclear reactors
submitted by /u/stormforce7916 [link] [comments]
13h
The fibroblast-derived protein PI16 controls neuropathic pain [Medical Sciences]
Chronic pain is a major clinical problem of which the mechanisms are incompletely understood. Here, we describe the concept that PI16, a protein of unknown function mainly produced by fibroblasts, controls neuropathic pain. The spared nerve injury (SNI) model of neuropathic pain increases PI16 protein levels in fibroblasts in dorsal…
7h
The Film That You Might Not Hear About but Have to See
The journey that Cookie Figowitz (played by John Magaro) took to get to the Oregon territory in 1820 was clearly a difficult one. As Kelly Reichardt's new film, First Cow ,opens, he's near the end of his trek, clambering over challenging terrain and dodging threats from his fur-trapping companions. By comparison, the voyage of the first cow to set foot in Oregon seems graceful: She enters the scr
7h
The habenular G-protein-coupled receptor 151 regulates synaptic plasticity and nicotine intake [Neuroscience]
The habenula, an ancient small brain area in the epithalamus, densely expresses nicotinic acetylcholine receptors and is critical for nicotine intake and aversion. As such, identification of strategies to manipulate habenular activity may yield approaches to treat nicotine addiction. Here we show that GPR151, an orphan G-protein–coupled receptor (GPCR) highly…
7h
The Jazz Great Behind One of the Most Famous Pairings in Music History
Walk into any jazz room, anywhere on Earth, on any night, and you'll probably hear a keyboardist copping McCoy Tyner's licks and tricks. Even though the piano player, who died Friday at 81, played in John Coltrane's classic quartet—one of the most famous and influential combos in history—his towering legacy was not a foregone conclusion. At the height of Tyner's career, his playing was sometimes
9h
The million-dollar trade in trafficked rosewood trees
For a year BBC Africa Eye has been investigating the million-dollar trade in trafficked rosewood.
14h
The Problem with Direct-to-Consumer Genetic Tests
Despite caveats in ads and on packages, users can fail to understand their limitations — Read more on ScientificAmerican.com
8h
The size of the immune repertoire of bacteria [Biophysics and Computational Biology]
Some bacteria and archaea possess an immune system, based on the CRISPR-Cas mechanism, that confers adaptive immunity against viruses. In such species, individual prokaryotes maintain cassettes of viral DNA elements called spacers as a memory of past infections. Typically, the cassettes contain several dozen expressed spacers. Given that bacteria can…
7h
The streetwise charity fighting childhood obesity
Environment blamed for poorest five-year olds being more likely to be overweight than the richest
19h
The temporal structure of the inner retina at a single glance
Scientific Reports, Published online: 10 March 2020; doi:10.1038/s41598-020-60214-z
13h
The Tol-Pal system is required for peptidoglycan-cleaving enzymes to complete bacterial cell division [Microbiology]
Tol-Pal is a multiprotein system present in the envelope of Gram-negative bacteria. Inactivation of this widely conserved machinery compromises the outer membrane (OM) layer of these organisms, resulting in hypersensitivity to many antibiotics. Mutants in the tol-pal locus fail to complete division and form cell chains. This phenotype along with…
6h
These Industrial Robots Get More Adept With Every Task
Vicarious, a secretive 10-year-old startup backed by Mark Zuckerberg, Elon Musk, and Jeff Bezos, reveals its progress and an initial customer.
13h