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One Big Challenge for Biden? China's Push for Tech Supremacy | WIRED
submitted by /u/onlyartist6 [link] [comments]
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There Could Be 300 Million (or More) Earth-Like Planets in Our Galaxy
submitted by /u/izumi3682 [link] [comments]
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Virgin Hyperloop completes first test ride with passengers
submitted by /u/solar-cabin [link] [comments]
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Coal Consumption In U.S. Electricity Sector Plunges 30%
submitted by /u/auscrisos [link] [comments]
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Virgin Hyperloop Completes Its First Ever Passenger Test
submitted by /u/auscrisos [link] [comments]
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'Robot soldiers could make up quarter of British army by 2030s'
submitted by /u/MesterenR [link] [comments]
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What societal 'norm' of today would be an unethical or just wrong thing in the future?
So, hi, it's my first time posting and I just thought this would be a great memorable post to start my account with, so I do apologise if I'm a bit awkward. Anways, back to the question; me and my brother were just having one of those dinner talks together and as our conversations drifted from memes and randomness, we found ourselves talking about political and societal issues; which of course, c
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Transparent Wood Could Be the Window of the Future
submitted by /u/Gari_305 [link] [comments]
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Microbe "rewiring" technique promises a boom in biomanufacturing
Berkeley Lab researchers have achieved unprecedented success in modifying a microbe to efficiently produce a compound of interest using a computational model and CRISPR-based gene editing. Their approach could dramatically speed up the research and development phase for new biomanufacturing processes, getting advanced bio-based products, such as sustainable fuels and plastic alternatives, on the s
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Do consumers enjoy events more when commenting on them?
Generating content increases people's enjoyment of positive experiences.
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Efforts needed to better integrate family caregivers into health care teams
An estimated 53 million family members and friends provide care assistance to loved ones in the United States, yet family caregivers face significant barriers coordinating their efforts with the formal health care team. A new study suggests changes the health care system can make to better integrate family members into the health care team.
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Covid-19: what's up with the coronavirus cough?
Linda Geddes speaks to Prof Jacky Smith about one of Covid-19's most consistent symptoms: the persistent dry cough. As winter arrives in the northern hemisphere, how do we tell the difference between the possible onset of the virus and the kind of routine coughs normally experienced at this time of year?. Help support our independent journalism at theguardian.com/sciencepod
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Covid-19: what's up with the coronavirus cough? – podcast
Linda Geddes speaks to Prof Jacky Smith about one of Covid-19's most consistent symptoms: the persistent dry cough. As winter arrives in the northern hemisphere, how do we tell the difference between the possible onset of the virus and the kind of routine coughs normally experienced at this time of year? Continue reading…
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Mink slaughter seeks to save Denmark from being a new Wuhan
A preventive Covid cull of 17m minks sets a crucial health precedent: the importance of overreacting
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Forskere opdager to nye arter af svævende kæmpe-pungdyr
Et af verdens største svævende pungdyr er i virkeligheden tre forskellige arter.
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What does the Pfizer Covid vaccine breakthrough mean for Australia?
Interim results show vaccine to be 90% effective, but findings have not been peer-reviewed, Australia has only secured enough for five million people, and there are concerns around its storage temperature • Pfizer says vaccine is 90% effective • What has Pfizer's vaccine trial found? • Vaccine announcement is cause for cautious celebration News that pharmaceutical giant Pfizer and partner company
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Champagne and questions greet first data showing that a COVID-19 vaccine works
Pfizer and BioNTech announced groundbreaking mRNA vaccine is 90% effective but provide little data so far
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Two-million-year-old skull of human 'cousin' unearthed
The fossil from a large-toothed species helps shed more light on how humans evolved, researchers say.
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Tre år efter kritik – Region Syd lukker for administratorrettigheder til 27.000 brugere
Rigsrevisionen kritiserede tilbage i 2017 Region Syddanmark for manglende it-sikkerhed – blandt andet ved at være meget generøs med lokaladministrator-titlerne. Nu har regionen, tre år efter, lukket for medarbejdernes lokale administrationsrettigheder.
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Eli Lilly's Antibody Treatment Gets Emergency F.D.A. Approval
The authorization raised immediate questions about who would get access to the antibody treatments, which are in short supply.
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Forbrændingsanlæg kan ikke følge med – nu skal mink i massegrave
PLUS. Det viser sig, at mink har en »rigtig god« brændværdi efter at affaldsforbrændingsanlæg i hele Danmark er begyndt at modtage nedslåede minkbesætninger til destruktion.
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The Atlantic Daily: Trump Won't Go Quietly
Every weekday evening, our editors guide you through the biggest stories of the day, help you discover new ideas, and surprise you with moments of delight. Subscribe to get this delivered to your inbox . MARK MAKELA / GETTY Donald Trump isn't going away. A majority of Americans served the 45th president an electoral rebuke, denying him a second term in the White House. But don't expect him to qui
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Eli Lilly receives authorisation for Covid-19 antibody treatment
US FDA gives emergency approval to bamlanivimab therapy designed to boost immune system
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Joe Biden: How the president-elect plans to tackle climate change
What will a Joe Biden presidency mean for the global battle against rising temperatures?
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Diet and lifestyle during pregnancy linked to modifications in infants' DNA
A new study has shown pregnant women with obesity could reduce the health risks for their infants through improved diet and more physical activity.
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New insight into a placental gene pathway and its association with vitamin D
Vitamin D status during pregnancy has multifaceted effects on maternal health. Researchers found that vitamin D sufficiency lowered the expression of placental genes related to preeclampsia – a severe, and sometimes fatal, condition. Their findings shed new light on the development of preeclampsia during pregnancy and how it may correlate with maternal vitamin D status.
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Operation Warp Speed's Logistics Chief Weighs In On Vaccine Progress
Gen. Gustave Perna says as soon as the FDA deems a vaccine safe and effective, his team is ready to coordinate deployment of tens of millions of doses as early as next month. (Image credit: Chip Somodevilla/AP)
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Why do bats fly into walls?
Bats sometimes collide with large walls even though they detect these walls with their sonar system. Researchers from Tel Aviv University have concluded that these collisions do not result from a sensory limitation but rather from an error in acoustic perception.
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Researchers identify new Rickettsia bacteria species in dogs
Researchers have identified a new species of Rickettsia bacteria that may cause significant disease in dogs and humans. This new yet unnamed species, initially identified in three dogs, is part of the spotted-fever group Rickettsia which includes Rickettsia rickettsii, the bacteria that cause Rocky Mountain Spotted Fever (RMSF).
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Warrior women: New evidence of ancient female big-game hunters
A recent archaeological dig in the Peruvian mountains uncovered evidence of ancient female big-game hunters. This adds to a growing consensus that women played a much bigger role in hunting than previously assumed. Gender assumptions are a constant throughout history, with culture often playing a more important role than biology. You've likely heard it like this: for most of history, women forage
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Tropical Storm Eta Makes Landfall in the Florida Keys
The 28th named storm of the Atlantic season brought strong winds and heavy rains late Sunday, the National Hurricane Center said.
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Skull Fossil Shows How Human Cousin Adapted to Changing Climate
A skull found in a South African cave suggests that the species went through a process of microevolution during a chaotic environmental shift.
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Coronavirus live news: WHO warns Covid 'not tired of us' as top UK scientist says vaccine 'feels like watershed moment'
US passes 10m cases; Italy extends restrictions in five regions; Biden announces Covid-19 advisory board Scientists react to vaccine news Covid-19 vaccine candidate is 90% effective, says manufacturer What has Pfizer's vaccine trial found and is this a breakthrough? New Covid lockdown in Hungary as Belgium passes second peak Italy 'faces 10,000 Covid deaths in a month' with no lockdown Follow all
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Loneliness a leading cause of depression in older adults
Loneliness is responsible for 18% of depression among people over 50 in England, according to a new study led by UCL researchers published in The Lancet Psychiatry.
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Severe COVID-19 infection rare in newborns
Severe COVID-19 infection appears rare in newborn babies, suggests a new study.
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'Diseases of despair' have soared over past decade in US
'Diseases of despair', such as substance abuse, alcohol dependency, and suicidal thoughts and behaviours, have soared in the US over the past decade, reveals an analysis of health insurance claims data published in the online journal BMJ Open.
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Pfizer claims its COVID-19 vaccine is 90 percent effective. Here's what that actually means.
A 90 percent effectiveness is very impressive, but the rate is based on a relatively small number of people. (Pixabay/) Follow all of PopSci's COVID-19 coverage here , including the truth about herd immunity , advice for pregnant women , and a tutorial on making your own mask . On Monday, pharmaceutical company Pfizer announced the latest results for their coronavirus vaccine, which is now in lat
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Republicans spent millions on last-minute voting ads on Facebook
On midnight of October 26, Facebook stopped accepting all new advertisements about "social issues, elections, or politics in the US." The intention was to prevent Facebook from being overwhelmed by a blitz of last-minute ads that would require fact-checking, and to limit the ability of political groups to sow confusion or violence. Advertisers were not blocked from running old ads, however: Faceb
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A normal tourist map, "but everything is negative"
Your standard tourist map is irrepressibly positive about its location—but not this one. Norwegian activist/artist Markus Moestue reveals the dark and shameful sides of Oslo. He hopes his 'Critical Tourist Map' will inspire others to reveal the dark side of their cities. "Only negative stuff about Oslo" Tourism is a conspiracy of euphemisms. Visitors only want to see the best parts of the places
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Human Evolution Isn't Over Yet
We shouldn't look at evolution as a thing of the past — it's happening right before our eyes.
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Top General Says "Robot Soldiers" Could Make Up 25 Percent of British Army
BattleBots Over the next decades, the British army may enlist tens of thousands of robotic soldiers . General Nick Carter, chief of defense staff for the British army, suggests that new drones and robots could make up a significant fraction of the armed forces, The Guardian reports . Part of the plan is to compensate for a drop in the number of human recruits — but, at the same time, Carter admit
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Build A Better Brain With This Memory Mastery Course
We've all experienced the bizarre quirks of memory — like where you can't recall your boss' wife's name, but you can… somehow sing an ad jingle that's been off the air for years. Why? Too often we think of memory as one vast file cabinet. The reality: We have multiple forms of memory. The memory you draw on to remember how to ride a bike is different from the type you use to recognize that it's t
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Large, delayed outbreaks of endemic diseases possible following COVID-19 controls
Measures such as mask wearing and social distancing that are key to reducing coronavirus infection have also greatly reduced the incidence of other diseases, such as influenza and respiratory syncytial virus (RSV). But Princeton researchers report that current reductions in these common respiratory infections, however, may increase people's susceptibility to these diseases, resulting in large futu
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Researchers identify new Rickettsia species in dogs
Researchers have identified a new species of Rickettsia bacteria that may cause significant disease in dogs and humans. This new yet unnamed species, initially identified in three dogs, is part of the spotted-fever group Rickettsia which includes Rickettsia rickettsii, the bacteria that cause Rocky Mountain Spotted Fever (RMSF).
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Foolproofing Microbiome Workflows
Simplifying microbiome research: from sample storage and management to sharing data across the globe!
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Elevate Your Mind With A One-Year Subscription To Omvana
By now, we all know how critical meditation and mindfulness are in reducing stress, managing negative emotions, and keeping a cool head under constant stimuli. But meditation can be so, so much more than that. And now, you can explore how that is — and all the benefits others using other courses are missing — for less with a 58% discount on one year of Omvana . More Than Stress Relief Meditation
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More Damage Reported at Alien-Hunting SETI Facility
Match SETI More bad news for the alien-hunting Arecibo Observatory in Puerto Rico. A second cable has fallen, crushing the intricate reflector dish below. A first auxiliary cable failed over the massive dish on August 10, crushing a portion of the dish and representing a significant setback for the observatory. The dish was mainly used to hunt for extraterrestrial life — but research had to be pu
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Pfizer's COVID-19 Vaccine 90 Percent Effective: Initial Data
Vaccine experts say the results surpass their expectations, but the study is not complete, and the data have not been peer reviewed.
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Don't be fooled by pretty food, USC research warns
Consumers confuse pretty food with healthy food, largely due to highly stylized presentations and marketing that appeal to aesthetics and appetite. Disclaimers could help people make more nutritious choices.
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Researchers isolate and decode brain signal patterns for specific behaviors
A standing challenge has been isolating patterns in brain signals that relate to a specific behavior, such as finger movements. Researchers have developed a machine learning algorithm that resolved this challenge by uncovering neural patterns missed by other methods. This could both enable new neuroscience discoveries and enhance future brain-machine interfaces.
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With inauguration 10 weeks away, Biden's pandemic plans face agonizing wait
Crisis could get much worse before new administration takes power
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Coughs of Many Colors: When Should You Be Worried About Phlegm?
Disgusting though they may be, phlegm and mucus are nothing to sneeze at. Here's what their appearance can tell you about your health.
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Micron Announces 176-Layer NAND, Volume Shipments Underway
Micron announced its 176-layer NAND flash today, and declared volume shipments to customers have already begun. This marks a new high-water point for commercial NAND density in absolute terms, and it will have a positive impact on the price of solid state storage in both the computing and the mobile phone markets. Micron is claiming a number of firsts with this 5th Generation 3D NAND, including a
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Asteroid Bennu Might Be Hollow and Doomed to Crumble
Bennu, one of the two objects used as a test case in the MIT study. NASA's OSIRIS-REx spacecraft has successfully scooped up a bucket-full of the asteroid Bennu , and it'll begin its journey back to Earth soon. Scientists will learn a great deal about the space rock once they get their hands on that sample, but we're already learning some surprising things based on data collected by OSIRIS-REx. A
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Why do bats fly into walls?
Bats sometimes collide with large walls even though they detect these walls with their sonar system. Researchers from Tel Aviv University have concluded that these collisions do not result from a sensory limitation but rather from an error in acoustic perception.
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All weight loss isn't equal for reducing heart failure risk
DALLAS – Nov. 9, 2020 – Reducing the level of body fat and waist size are linked to a lower risk of heart failure in patients with type 2 diabetes, a study led by UT Southwestern researchers indicates. The findings, reported today in Circulation , suggest that all weight loss isn't equal when it comes to mitigating the risk of heart disease.
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Oregon decriminalizes drugs: Here are 3 metrics other states will track
Oregon voted to decriminalize possession of small amounts of all drugs, including heroin, cocaine and methamphetamine. The state also legalized the therapeutic use and sale of psilocybin mushrooms. As the laws go into effect, other U.S. states will be watching to see how the experiment plays out, influencing future votes across the country. Amid the uncertainty of the unfolding U.S. 2020 presiden
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Researchers use 'big data' approach to identify melatonin as possible COVID-19 treatment
A new study suggests that melatonin, a hormone that regulates the sleep-wake cycle and is commonly used as an over-the-counter sleep aid, may be a viable treatment option for COVID-19.
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Amazon fires cause Brazil's CO2 emissions to jump amid pandemic
Forest fires have sent carbon dioxide emissions soaring in Brazil over the past two years, undermining efforts by the government of President Jair Bolsonaro to restore the country's environmental credentials.
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Groups fight to keep gray wolf protections for most of US
Wildlife advocates and environmental groups have announced that they are challenging the removal of federal protections for gray wolves across most of the U.S.
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Groups fight to keep gray wolf protections for most of US
Wildlife advocates and environmental groups have announced that they are challenging the removal of federal protections for gray wolves across most of the U.S.
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Researchers decode thermal conductivity with light
Groundbreaking science is often the result of true collaboration, with researchers in a variety of fields, viewpoints and experiences coming together in a unique way. One such effort by Clemson University researchers has led to a discovery that could change the way the science of thermoelectrics moves forward.
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Biden May Slow Down Moon Program to Focus NASA on Climate Change
Looking Inward When Joe Biden takes office, NASA may find itself making a hard pivot. The Trump administration brought about a major drive to explore outward, with ambitious goals like sending crewed missions to the Moon and and eventually Mars . But Biden may be less interested in crewed missions, SpaceNews reports , potentially putting them on the backburner for a renewed focus on studying clim
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The impact of COVID-19 nonpharmaceutical interventions on the future dynamics of endemic infections [Ecology]
Nonpharmaceutical interventions (NPIs) have been employed to reduce the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), yet these measures are already having similar effects on other directly transmitted, endemic diseases. Disruptions to the seasonal transmission patterns of these diseases may have consequences for the timing and severity of…
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Identification of a brainstem locus that inhibits tumor necrosis factor [Immunology and Inflammation]
In the brain, compact clusters of neuron cell bodies, termed nuclei, are essential for maintaining parameters of host physiology within a narrow range optimal for health. Neurons residing in the brainstem dorsal motor nucleus (DMN) project in the vagus nerve to communicate with the lungs, liver, gastrointestinal tract, and other…
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Superconductivity, correlated insulators, and Wess-Zumino-Witten terms in twisted bilayer graphene [Physics]
Recent experiments on twisted bilayer graphene have shown a high-temperature parent state with massless Dirac fermions and broken electronic flavor symmetry; superconductivity and correlated insulators emerge from this parent state at lower temperatures. We propose that the superconducting and correlated insulating orders are connected by Wess–Zumino–Witten terms, so that defects…
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Selection on phenotypic plasticity favors thermal canalization [Evolution]
Climate change affects organisms worldwide with profound ecological and evolutionary consequences, often increasing population extinction risk. Climatic factors can increase the strength, variability, or direction of natural selection on phenotypic traits, potentially driving adaptive evolution. Phenotypic plasticity in relation to temperature can allow organisms to maintain fitness in response to
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Profile of Masayori Inouye [Profiles]
Masayori Inouye, a distinguished professor at the Rutgers Robert Wood Johnson Medical School, has cut a wide swath in biochemistry and molecular biology. His wide-ranging accomplishments include the determination of genetic codons in a protein and thus, for the first time, a partial DNA sequence of a gene, elucidation of…
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Observation of non-Hermitian topology and its bulk-edge correspondence in an active mechanical metamaterial [Physics]
Topological edge modes are excitations that are localized at the materials' edges and yet are characterized by a topological invariant defined in the bulk. Such bulk–edge correspondence has enabled the creation of robust electronic, electromagnetic, and mechanical transport properties across a wide range of systems, from cold atoms to metamaterials,…
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Neuropsychological and neuropathological observations of a long-studied case of memory impairment [Neuroscience]
We report neuropsychological and neuropathological findings for a patient (A.B.), who developed memory impairment after a cardiac arrest at age 39. A.B. was a clinical psychologist who, although unable to return to work, was an active participant in our neuropsychological studies for 24 y. He exhibited a moderately severe and…
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Coupling of light and mechanics in a photonic crystal waveguide [Applied Physical Sciences]
Observations of thermally driven transverse vibration of a photonic crystal waveguide (PCW) are reported. The PCW consists of two parallel nanobeams whose width is modulated symmetrically with a spatial period of 370 nm about a 240-nm vacuum gap between the beams. The resulting dielectric structure has a band gap (i.e.,…
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Scaling confirmation of the thermodynamic dislocation theory [Applied Physical Sciences]
The thermodynamic dislocation theory (TDT) is based on two highly unconventional assumptions: first, that driven systems containing large numbers of dislocations are subject to the second law of thermodynamics and second, that the controlling inverse timescale for these systems is the thermally activated rate at which entangled pairs of dislocations…
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Ammonium transporter expression in sperm of the disease vector Aedes aegypti mosquito influences male fertility [Cell Biology]
The ammonium transporter (AMT)/methylammonium permease (MEP)/Rhesus glycoprotein (Rh) family of ammonia (NH3/NH4+) transporters has been identified in organisms from all domains of life. In animals, fundamental roles for AMT and Rh proteins in the specific transport of ammonia across biological membranes to mitigate ammonia toxicity and aid in osmoregulation, acid–base…
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Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis [Microbiology]
Kinetoplastids are unicellular eukaryotic parasites responsible for such human pathologies as Chagas disease, sleeping sickness, and leishmaniasis. They have a single large mitochondrion, essential for the parasite survival. In kinetoplastid mitochondria, most of the molecular machineries and gene expression processes have significantly diverged and specialized, with an extreme example being…
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The potassium channel subunit Kv{beta}1 serves as a maȷor control point for synaptic facilitation [Neuroscience]
Analysis of the presynaptic action potential's (APsyn) role in synaptic facilitation in hippocampal pyramidal neurons has been difficult due to size limitations of axons. We overcame these size barriers by combining high-resolution optical recordings of membrane potential, exocytosis, and Ca2+ in cultured hippocampal neurons. These recordings revealed a critical and…
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Increasing risk of another Cape Town "Day Zero" drought in the 21st century [Earth, Atmospheric, and Planetary Sciences]
Three consecutive dry winters (2015–2017) in southwestern South Africa (SSA) resulted in the Cape Town "Day Zero" drought in early 2018. The contribution of anthropogenic global warming to this prolonged rainfall deficit has previously been evaluated through observations and climate models. However, model adequacy and insufficient horizontal resolution make it…
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Deep learning in deep time [Commentaries]
Digitized natural history records, now numbering in the billions (1), span widely across the tree of life and provide the foundation for numerous recent advances in biodiversity research (2, 3). Mechanistic insights are emerging for old questions, including how diversity has expanded and contracted through Earth's history (4), how species…
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A facile method of mapping HIV-1 neutralizing epitopes using chemically masked cysteines and deep sequencing [Applied Biological Sciences]
Identification of specific epitopes targeted by neutralizing antibodies is essential to advance epitope-based vaccine design strategies. We report a facile methodology for rapid epitope mapping of neutralizing antibodies (NAbs) against HIV-1 Envelope (Env) at single-residue resolution, using Cys labeling, viral neutralization assays, and deep sequencing. This was achieved by the…
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Pest pressure relates to similarity of crops and native plants [Commentaries]
Since the Green Revolution, scientists have documented countless unanticipated consequences of widespread pesticide use in agriculture. These consequences are balanced by the growing necessity to manage agricultural pests. The trade-offs have motivated research to produce inexpensive and accessible food while simultaneously improving the sustainability of agriculture from field to fork….
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Rerouting of ribosomal proteins into splicing in plant organelles [Plant Biology]
Production and expression of RNA requires the action of multiple RNA-binding proteins (RBPs). New RBPs are most often created by novel combinations of dedicated RNA-binding modules. However, recruiting existing genes to create new RBPs is also an important evolutionary strategy. In this report, we analyzed the eight-member uL18 ribosomal protein…
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Deafness mutation D572N of TMC1 destabilizes TMC1 expression by disrupting LHFPL5 binding [Neuroscience]
Transmembrane channel-like protein 1 (TMC1) and lipoma HMGIC fusion partner-like 5 (LHFPL5) are recognized as two critical components of the mechanotransduction complex in inner-ear hair cells. However, the physical and functional interactions of TMC1 and LHFPL5 remain largely unexplored. We examined the interaction between TMC1 and LHFPL5 by using multiple…
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On the way to understanding Yb2Ti2O7 [Commentaries]
As the history of science shows, research is rarely a linear process. Rather, it is built more like the roots of a tree, which branches out, retraces its steps, hesitates, and stammers, even if, on a larger scale, progress is palpable. Often, research is slow to provide answers, but, over…
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Michler's hydrol blue elucidates structural differences in prion strains [Biophysics and Computational Biology]
Yeast prions provide self-templating protein-based mechanisms of inheritance whose conformational changes lead to the acquisition of diverse new phenotypes. The best studied of these is the prion domain (NM) of Sup35, which forms an amyloid that can adopt several distinct conformations (strains) that confer distinct phenotypes when introduced into cells…
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Correction for Polymenidou et al., Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection [Corrections]
Colloquium Correction for "Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection," by Magdalini Polymenidou, Frank L. Heppner, Erica C. Pellicioli, Eduard Urich, Gino Miele, Nathalie Braun, Franziska Wopfner, Hermann M. Schätzl, Burkhard Becher, and Adriano Aguzzi, which was first published August 3, 2004; 10.1073/pnas.0404772101 (Proc. Natl….
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Discovery of small-molecule inhibitors of multidrug-resistance plasmid maintenance using a high-throughput screening approach [Microbiology]
Carbapenem-resistant Enterobacteriaceae (CRE) are multidrug-resistant pathogens for which new treatments are desperately needed. Carbapenemases and other types of antibiotic resistance genes are carried almost exclusively on large, low-copy-number plasmids (pCRE). Accordingly, small molecules that efficiently evict pCRE plasmids should restore much-needed treatment options. We therefore designed a
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The 3 x 120{degrees} rotary mechanism of Paracoccus denitrificans F1-ATPase is different from that of the bacterial and mitochondrial F1-ATPases [Biochemistry]
The rotation of Paracoccus denitrificans F1-ATPase (PdF1) was studied using single-molecule microscopy. At all concentrations of adenosine triphosphate (ATP) or a slowly hydrolyzable ATP analog (ATPγS), above or below Km, PdF1 showed three dwells per turn, each separated by 120°. Analysis of dwell time between steps showed that PdF1 executes…
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Rapid reductions and millennial-scale variability in Nordic Seas sea ice cover during abrupt glacial climate changes [Earth, Atmospheric, and Planetary Sciences]
Constraining the past sea ice variability in the Nordic Seas is critical for a comprehensive understanding of the abrupt Dansgaard-Oeschger (D-O) climate changes during the last glacial. Here we present unprecedentedly detailed sea ice proxy evidence from two Norwegian Sea sediment cores and an East Greenland ice core to resolve…
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Underpotential lithium plating on graphite anodes caused by temperature heterogeneity [Chemistry]
Rechargeability and operational safety of commercial lithium (Li)-ion batteries demand further improvement. Plating of metallic Li on graphite anodes is a critical reason for Li-ion battery capacity decay and short circuit. It is generally believed that Li plating is caused by the slow kinetics of graphite intercalation, but in this…
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Enhanced and stabilized hydrogen production from methanol by ultrasmall Ni nanoclusters immobilized on defect-rich h-BN nanosheets [Chemistry]
Employing liquid organic hydrogen carriers (LOHCs) to transport hydrogen to where it can be utilized relies on methods of efficient chemical dehydrogenation to access this fuel. Therefore, developing effective strategies to optimize the catalytic performance of cheap transition metal-based catalysts in terms of activity and stability for dehydrogenation of LOHCs…
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Reconciling print-size and display-size constraints on reading [Psychological and Cognitive Sciences]
Two fundamental constraints limit the number of characters in text that can be displayed at one time—print size and display size. These dual constraints conflict in two important situations—when people with normal vision read text on small digital displays, and when people with low vision read magnified text. Here, we…
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Water oxidation by photosystem II is the primary source of electrons for sustained H2 photoproduction in nutrient-replete green algae [Biochemistry]
The unicellular green alga Chlamydomonas reinhardtii is capable of photosynthetic H2 production. H2 evolution occurs under anaerobic conditions and is difficult to sustain due to 1) competition between [FeFe]-hydrogenase (H2ase), the key enzyme responsible for H2 metabolism in algae, and the Calvin–Benson–Bassham (CBB) cycle for photosynthetic reductants and 2) inactivation…
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Label-free adaptive optics imaging of human retinal macrophage distribution and dynamics [Medical Sciences]
Microglia are resident central nervous system macrophages and the first responders to neural injury. Until recently, microglia have been studied only in animal models with exogenous or transgenic labeling. While these studies provided a wealth of information on the delicate balance between neuroprotection and neurotoxicity within which these cells operate,…
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Evolution of the genetic code; Evidence from serine codon use disparity in Escherichia coli [Genetics]
Among the 20 amino acids, three of them—leucine (Leu), arginine (Arg), and serine (Ser)—are encoded by six different codons. In comparison, all of the other 17 amino acids are encoded by either 4, 3, 2, or 1 codon. Peculiarly, Ser is separated into two disparate Ser codon boxes, differing by…
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Correction for Kossin et al., Global increase in major tropical cyclone exceedance probability over the past four decades [Corrections]
EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES Correction for "Global increase in major tropical cyclone exceedance probability over the past four decades," by James P. Kossin, Kenneth R. Knapp, Timothy L. Olander, and Christopher S. Velden, which was first published May 18, 2020; 10.1073/pnas.1920849117 (Proc. Natl. Acad. Sci. U.S.A. 117, 11975–11980). The…
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Excess of the NF-ĸB p50 subunit generated by the ubiquitin ligase KPC1 suppresses tumors via PD-L1- and chemokines-mediated mechanisms [Medical Sciences]
Nuclear factor–ĸB (NF-ĸB) transcription factor is a family of essential regulators of the immune response and cell proliferation and transformation. A typical factor is a heterodimer made of either p50 or p52, which are limited processing products of either p105 or p100, respectively, and a member of the Rel family…
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Overkill, glacial history, and the extinction of North America's Ice Age megafauna [Perspectives]
The end of the Pleistocene in North America saw the extinction of 38 genera of mostly large mammals. As their disappearance seemingly coincided with the arrival of people in the Americas, their extinction is often attributed to human overkill, notwithstanding a dearth of archaeological evidence of human predation. Moreover, this…
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Oncogenic allelic interaction in Xiphophorus highlights hybrid incompatibility [Genetics]
Mixing genomes of different species by hybridization can disrupt species-specific genetic interactions that were adapted and fixed within each species population. Such disruption can predispose the hybrids to abnormalities and disease that decrease the overall fitness of the hybrids and is therefore named as hybrid incompatibility. Interspecies hybridization between southern…
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High-resolution land value maps reveal underestimation of conservation costs in the United States [Sustainability Science]
The justification and targeting of conservation policy rests on reliable measures of public and private benefits from competing land uses. Advances in Earth system observation and modeling permit the mapping of public ecosystem services at unprecedented scales and resolutions, prompting new proposals for land protection policies and priorities. Data on…
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The origin of secondary microseism Love waves [Earth, Atmospheric, and Planetary Sciences]
The interaction of ocean surface waves produces pressure fluctuations at the seafloor capable of generating seismic waves in the solid Earth. The accepted mechanism satisfactorily explains secondary microseisms of the Rayleigh type, but it does not justify the presence of transversely polarized Love waves, nevertheless widely observed. An explanation for…
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Exploitative leaders incite intergroup warfare in a social mammal [Evolution]
Collective conflicts among humans are widespread, although often highly destructive. A classic explanation for the prevalence of such warfare in some human societies is leadership by self-serving individuals that reap the benefits of conflict while other members of society pay the costs. Here, we show that leadership of this kind…
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Correction to Supporting Information for Morales-Castilla et al., Diversity buffers winegrowing regions from climate change losses [SI Correction]
SUSTAINABILITY SCIENCE Correction to Supporting Information for "Diversity buffers winegrowing regions from climate change losses," by Ignacio Morales-Castilla, Iñaki García de Cortázar-Atauri, Benjamin I. Cook, Thierry Lacombe, Amber Parker, Cornelis van Leeuwen, Kimberly A. Nicholas, and Elizabeth M. Wolkovich, which was first published January 27, 2020; 10.1073/pnas.1906731117 (Proc. Natl. Acad
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A climatic dipole drives short- and long-term patterns of postfire forest recovery in the western United States [Ecology]
Researchers are increasingly examining patterns and drivers of postfire forest recovery amid growing concern that climate change and intensifying fires will trigger ecosystem transformations. Diminished seed availability and postfire drought have emerged as key constraints on conifer recruitment. However, the spatial and temporal extent to which recurring modes of climatic…
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Insights into coral bleaching under heat stress from analysis of gene expression in a sea anemone model system [Genetics]
Loss of endosymbiotic algae ("bleaching") under heat stress has become a major problem for reef-building corals worldwide. To identify genes that might be involved in triggering or executing bleaching, or in protecting corals from it, we used RNAseq to analyze gene-expression changes during heat stress in a coral relative, the…
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Assembly of the peripheral stalk of ATP synthase in human mitochondria [Biochemistry]
The adenosine triphosphate (ATP) synthase in human mitochondria is a membrane bound assembly of 29 proteins of 18 kinds organized into F1-catalytic, peripheral stalk (PS), and c8-rotor ring modules. All but two membrane components are encoded in nuclear genes, synthesized on cytoplasmic ribosomes, imported into the mitochondrial matrix, and assembled…
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Marine wild-capture fisheries after nuclear war [Sustainability Science]
Nuclear war, beyond its devastating direct impacts, is expected to cause global climatic perturbations through injections of soot into the upper atmosphere. Reduced temperature and sunlight could drive unprecedented reductions in agricultural production, endangering global food security. However, the effects of nuclear war on marine wild-capture fisheries, which significantly contribute…
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Stac protein regulates release of neuropeptides [Neuroscience]
Neuropeptides are important for regulating numerous neural functions and behaviors. Release of neuropeptides requires long-lasting, high levels of cytosolic Ca2+. However, the molecular regulation of neuropeptide release remains to be clarified. Recently, Stac3 was identified as a key regulator of L-type Ca2+ channels (CaChs) and excitation–contraction coupling in vertebrate skeletal…
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Correction for Yaron et al., Forelimb force direction and magnitude independently controlled by spinal modules in the macaque [Corrections]
NEUROSCIENCE Correction for "Forelimb force direction and magnitude independently controlled by spinal modules in the macaque," by Amit Yaron, David Kowalski, Hiroaki Yaguchi, Tomohiko Takei, and Kazuhiko Seki, which was first published October 15, 2020; 10.1073/pnas.1919253117 (Proc. Natl. Acad. Sci. U.S.A. 117, 27655–27666). The authors note that Table 1 appeared…
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Correction for Ahmad et al., Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule [Corrections]
BIOCHEMISTRY Correction for "Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule," by Md. Faiz Ahmad, Intekhab Alam, Sarah E. Huff, John Pink, Sheryl A. Flanagan, Donna Shewach, Tessianna A. Misko, Nancy L. Oleinick, William E. Harte, Rajesh Viswanathan, Michael E. Harris, and Chris Godfrey Dealwis, which…
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Correction for Huang et al., Mechanism of water extraction from gypsum rock by desert colonizing microorganisms [Corrections]
BIOPHYSICS AND COMPUTATIONAL BIOLOGY, MICROBIOLOGY Correction for "Mechanism of water extraction from gypsum rock by desert colonizing microorganisms," by Wei Huang, Emine Ertekin, Taifeng Wang, Luz Cruz, Micah Dailey, Jocelyne DiRuggiero, and David Kisailus, which was first published May 4, 2020; 10.1073/pnas.2001613117 (Proc. Natl. Acad. Sci. U.S.A. 117, 10681–10687). The…
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Potential for sustainable irrigation expansion in a 3 {degrees}C warmer climate [Agricultural Sciences]
Climate change is expected to affect crop production worldwide, particularly in rain-fed agricultural regions. It is still unknown how irrigation water needs will change in a warmer planet and where freshwater will be locally available to expand irrigation without depleting freshwater resources. Here, we identify the rain-fed cropping systems that…
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Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein [Biochemistry]
P-glycoprotein (P-gp), also known as ABCB1, is a cell membrane transporter that mediates the efflux of chemically dissimilar amphipathic drugs and confers resistance to chemotherapy in most cancers. Homologous transmembrane helices (TMHs) 6 and 12 of human P-gp connect the transmembrane domains with its nucleotide-binding domains, and several residues in…
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Master curve of boosted diffusion for 10 catalytic enzymes [Biophysics and Computational Biology]
Molecular agitation more rapid than thermal Brownian motion is reported for cellular environments, motor proteins, synthetic molecular motors, enzymes, and common chemical reactions, yet that chemical activity coupled to molecular motion contrasts with generations of accumulated knowledge about diffusion at equilibrium. To test the limits of this idea, a critical…
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The quest for improved air quality may push China to continue its CO2 reduction beyond the Paris Commitment [Environmental Sciences]
China is challenged with the simultaneous goals of improving air quality and mitigating climate change. The "Beautiful China" strategy, launched by the Chinese government in 2020, requires that all cities in China attain 35 μg/m3 or below for annual mean concentration of PM2.5 (particulate matter with aerodynamic diameter less than…
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A breakthrough in understanding the molecular basis of coral heat tolerance [Commentaries]
Reef-building corals are cnidarian animals (Anthozoa, Scleractinia) that mostly live in colonies composed of hundreds of thousands of tiny coral polyps. The polyps house dinoflagellate algal photosymbionts of the family Symbiodiniaceae inside their gastrodermal cells (Fig. 1A), and this mutualistic association builds the three-dimensional structure of the reefs via deposition…
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A majority of Rhodobacter sphaeroides promoters lack a crucial RNA polymerase recognition feature, enabling coordinated transcription activation [Biochemistry]
Using an in vitro transcription system with purified RNA polymerase (RNAP) to investigate rRNA synthesis in the photoheterotrophic α-proteobacterium Rhodobacter sphaeroides, we identified a surprising feature of promoters recognized by the major holoenzyme. Transcription from R. sphaeroides rRNA promoters was unexpectedly weak, correlating with absence of −7T, the very highly…
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Reduced thermal tolerance in a coral carrying CRISPR-induced mutations in the gene for a heat-shock transcription factor [Genetics]
Reef-building corals are keystone species that are threatened by anthropogenic stresses including climate change. To investigate corals' responses to stress and other aspects of their biology, numerous genomic and transcriptomic studies have been performed, generating many hypotheses about the roles of particular genes and molecular pathways. However, it has not…
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REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks [Genetics]
REV1/POLζ-dependent mutagenic translesion synthesis (TLS) promotes cell survival after DNA damage but is responsible for most of the resulting mutations. A novel inhibitor of this pathway, JH-RE-06, promotes cisplatin efficacy in cancer cells and mouse xenograft models, but the mechanism underlying this combinatorial effect is not known. We report that,…
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Social media can influence stock returns, finance professor says
Twitter's impact is not limited to news, sports and political opinions.
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Study finds surprising diversity in early child care
A new study of kindergarteners in one Midwestern state identified seven different pathways the children took in their early education and care before arriving at school. The researchers were surprised by the diverse experiences that kids brought with them to kindergarten: While some received care only in their home or mainly in a child care center, others switched back and forth between different
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'A great day for humanity' – and not bad for the stock market either | Nils Pratley
We mustn't get carried away but the strong reaction to the Pfizer-BioNTec trial results makes sense "A great day for science and humanity," said the Pfizer chief executive, Albert Bourla. It was a decent one for stock markets too. The FTSE 100 index rose almost 5% as the US firm and its German partner, BioNTech, reported promising initial results from their Covid vaccine trial. There is an obviou
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Scientists Discover a "Failed Star" Too Cold to Show up in Normal Scans
Tuning In For the first time, scientists discovered a brown dwarf — sometimes referred to as failed stars or super-planets because they exist in a gray area between gas giant planets and small stars — using an unprecedented technique. Typically, these bizarre celestial objects get picked up on infrared sweeps of the night sky . But a team of astronomers from Hawaii and the Netherlands used a new
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New insight into a placental gene pathway and its association with vitamin D
Vitamin D status during pregnancy has multifaceted effects on maternal health. In an article in Pregnancy Hypertension , researchers at the Medical University of South Carolina found that vitamin D sufficiency lowered the expression of placental genes related to preeclampsia – a severe, and sometimes fatal, condition. Their findings shed new light on the development of preeclampsia during pregnanc
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11 Things You Need to Know About Pfizer's Covid Vaccine
What's the big deal? Was it part of Operation Warp Speed? When can you get one?
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Clemson researchers decode thermal conductivity with light
Clemson researchers examine a highly efficient thermoelectric material in a new way – by using light.
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COVID Misinformation a Roadblock to Curbing Pandemic
Two new studies suggest that the spread of misinformation about COVID-19 will make it harder for communities to bring the pandemic under control. stereotypes and fears of stigma may be barriers to COVID testing, a finding that confirms previous studies about stigma around HIV and Ebola. And believing COVID conspiracies makes people less likely to support public health policies to reduce the spread
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Putting stock into Twitter: Social media can influence returns, WVU finance professor says
Alexander Kurov, Fred T. Tattersall Research Chair and Professor of Finance in the John Chambers College of Business and Economics, found that firm-level Twitter content has information useful for predicting next-day stock returns, and that it is a stronger predictor of returns for firms with less analyst coverage.
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Female mongooses start battles for chance to mate
Female banded mongooses lead their groups into fights then try to mate with enemy males in the chaos of battle, new research shows.
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A better understanding of coral skeleton growth suggests ways to restore reefs
In a new study, University of Wisconsin-Madison physicists observed reef-forming corals at the nanoscale and identified how they create their skeletons. The results provide an explanation for how corals are resistant to acidifying oceans and suggest that controlling water temperature, not acidity, is crucial to mitigating loss and restoring reefs.
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Global fisheries could alleviate a global food emergency in extreme situations
A new international study argues that, if managed sustainably in advance, global fisheries could alleviate food shortages even after a nuclear war.
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Just 1 month in greener play areas could boost kids' immune systems, study says
Making outdoor play areas greener and more biodiverse could improve children's immune systems in one month, a new study suggests. Scientists in Finland covered the playgrounds of city preschools with forest undergrowth, lawn turf and planter boxes. After 28 days, the experimental study found the children (aged three to five) in the modified playgrounds appeared to have a greater diversity of micr
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Stream Everything With This Complete Entertainment Bundle
Winter's coming up, and no matter how the rest of 2020 goes, you're probably going to be spending more time inside — and thus, more time streaming. The Complete Entertainment Bundle, featuring a year of PlayStation Plus , will keep you learning, streaming, relaxing, and sleeping well for $199.99, a savings of 80%. PlayStation Plus: 1-Yr Subscription Get free games, play multiplayer with friends,
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New black hole merger simulations could help power next-gen gravitational wave detectors
Scientists have developed new simulations of black holes with widely varying masses merging that could help power the next generation of gravitational wave detectors.
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Global analysis of forest management shows local communities often lose out
Maintaining forest cover is an important natural climate solution, but new research shows that too often, communities lose out when local forest management is formalized.
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Menstrual cycle length and body temperature change with age and seasons
Researchers using Big Data have shown that the average length of the menstrual cycle in Japanese women peaks at 23 years with a trough at 45. Body temperature was consistent for the follicular phase of the cycle, but the average during the luteal phase peaks and stabilizes in the thirties, declining after 42. These findings replace outdated statistics and are relevant for research into female repr
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You drive like a girl: Study shows gender bias in perceptions of ride-sharing performance
Gender discrimination continues to plague organizations, and "gig economy" businesses, which have thrived over the last decade, are not immune, according to new research from the University of Notre Dame.
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Female banded mongooses lead battle for chance to find mates
When families of banded mongooses prepare to fight, they form battle lines.
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A better understanding of coral skeleton growth suggests ways to restore reefs
Coral reefs are vibrant communities that host a quarter of all species in the ocean and are indirectly crucial to the survival of the rest. But they are slowly dying—some estimates say 30 to 50 percent of reefs have been lost—due to climate change.
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Nuclear war could take a big bite out of the world's seafood
A new study reveals the damage that a nuclear war might take on wild-caught seafood around the world, from salmon and tuna to the shrimp in shrimp cocktails.
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In a warming world, Cape Town's 'Day Zero' drought won't be an anomaly
Today, the lakes around Cape Town are brimming with water, but it was only a few years ago that South Africa's second-most populous city made global headlines as a multi-year drought depleted its reservoirs, impacting millions of people. That kind of extreme event may become the norm, researchers now warn.
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Gene editing study finds gene for heat tolerance in corals
An international research project has used gene-editing technology to examine the heat tolerance of Great Barrier Reef coral with the results set to guide efforts in combatting the effects of climate change.
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Study finds surprising diversity in early child care
A new study of kindergarteners in one Midwestern state identified seven different pathways the children took in their early education and care before arriving at school.
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New study defines life cycle of a destructive plant pathogen 142 years after its discovery
Found in more than 60 countries, cruciferous clubroot disease is one of the most destructive plant diseases, causing so-called tumors on the roots of Brassicaceae crops and resulting in huge yield losses annually. The causal agent of this disease, Plasmodiophora brassicae, was first discovered by Russian biologist M. S. Woronin in 1878. Despite this early discovery, the life history of the pathoge
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A second cable fails at NSF's Arecibo Observatory in Puerto Rico
A main cable that supports the Arecibo Observatory broke Friday at 7:39 p.m. Puerto Rico time.
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Female banded mongooses lead battle for chance to find mates
When families of banded mongooses prepare to fight, they form battle lines.
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Is It Possible to Replace Alex Trebek?
Alex Trebek at a book signing in New York City in 1990 (Ron Galella / Getty) When Alex Trebek began hosting Jeopardy , Ronald Reagan was in his first term, Ghostbusters was a recent box-office hit, and most Millennials hadn't been born yet. Now, after nearly four decades, his time behind the podium is done. Trebek, a TV icon, died over the weekend from pancreatic cancer that he was diagnosed with
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Free birth control cut unintended pregnancy income gap
Research links the Affordable Care Act's elimination of out-of-pocket costs for contraception with fewer births, especially among low-income families. Nearly half of pregnancies in the US are unplanned, and there's a wide gap between the most affluent women who are likely to have access to the most reliable forms of birth control and those from lower income households. "Reducing unintended pregna
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Correct Weight Handling: Ten Practical Tips
Download this infographic to learn how accurate balance testing starts with proper reference weight handling and storage!
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Cleveland Clinic researchers identify melatonin as possible COVID-19 treatment
CLEVELAND – Results from a new Cleveland Clinic-led study suggest that melatonin, a hormone that regulates the sleep-wake cycle and is commonly used as an over-the-counter sleep aid, may be a viable treatment option for COVID-19.
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Study finds patients prefer doctors who share their same race/ethnicity
Patients who shared the same racial or ethnic background as their physician were more likely to give the maximum patient rating score, according to a new analysis of 117,589 patient surveys from 2014 to 2017.
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Gene editing study finds gene for heat tolerance in corals
An international research project has used gene-editing technology to examine the heat tolerance of Great Barrier Reef coral with the results set to guide efforts in combatting the effects of climate change.
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New study defines life cycle of a destructive plant pathogen 142 years after its discovery
Found in more than 60 countries, cruciferous clubroot disease is one of the most destructive plant diseases, causing so-called tumors on the roots of Brassicaceae crops and resulting in huge yield losses annually. The causal agent of this disease, Plasmodiophora brassicae, was first discovered by Russian biologist M. S. Woronin in 1878. Despite this early discovery, the life history of the pathoge
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Second cable breaks at Puerto Rico's Arecibo telescope
Researchers worried for future of iconic radio telescope after second cable tears through its dish
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New black hole merger simulations could help power next-gen gravitational wave detectors
Rochester Institute of Technology scientists have developed new simulations of black holes with widely varying masses merging that could help power the next generation of gravitational wave detectors. RIT Professor Carlos Lousto and Research Associate James Healy from RIT's School of Mathematical Sciences outline these record-breaking simulations in a new Physical Review Letters paper.
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Fossil feces hows fishy lunches from 200 million years ago
A new study of coprolites, fossil feces, shows the detail of food webs in the ancient shallow seas around Bristol in south-west England. One hungry fish ate part of the head of another fish before snipping off the tail of a passing reptile.
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3D model shows bacterial motor in action
Scientists have constructed a high-resolution 3D model that shows what happens when a bacterial motor switches directions.
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Genetic disposition protects immune system from aging
A genetic disposition that plays a role in the development of the heart in the embryo also appears to play a key role in the human immune system.
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First brown dwarf discovered by radio observations confirmed
New research has led to the first direct discovery of a cold brown dwarf from its radio wavelength emission. Along with paving the way for future brown dwarf discoveries, this result is an important step towards applying radio astronomy to the exciting field of exoplanets.
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US president-elect Joe Biden must quickly restore science to government
Nature, Published online: 09 November 2020; doi:10.1038/d41586-020-03081-y The election of Biden and Kamala Harris is a win for facts, research and empathy. Each of these must be deployed to fight the pandemic, combat misinformation, mitigate climate change and rebuild the United States' global relationships.
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Single cancer cell samples may boost custom treatment
Thanks to a new 3D cell culture technique, it may be possible to personalize treatment by understanding the contributions of different cell types in a tumor to the cancer's behavior. Each cancer patient's tumors have cells that look and act differently, making it difficult for scientists to determine treatments based on tumors grown from generic cell cultures in the lab. "Creating specific treatm
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Electric Wingsuit Lets You Fly at 186 MPH
Powered Wingsuit Engineers at German carmaker BMW's Designworks studio have created a chest-mounted set of electric impellers that allow a wingsuit to accelerate to a blistering 186 mph, New Atlas reports . Rather than just gliding, like a conventional wingsuit, the BMW propulsion system can put out 20 horsepower, allowing its wearer to actually gain back altitude — albeit only as long as the sui
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Noise may up chance of Alzheimer's disease
Ten decibels more daytime neighborhood noise is associated with 36% higher odds of mild cognitive impairment and 30% higher odds of Alzheimer's disease, according to a new study. Alzheimer's disease and other forms of dementia affect millions of older adults in the US—but not equally. Past research has identified risk factors including genes, education, racism, and air pollution, and a growing nu
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Optimizing Samples for RNA Sequencing
Download this ebook to learn how reliable RNA sequencing data starts with quality single-cell isolation approaches!
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NYUAD researchers develop protocol for a more accurate COVID-19 testing technique
Researchers from NYU Abu Dhabi's Biology Program and Center for Genomics and Systems Biology (CGSB) have implemented a new three-step testing approach that promises to significantly – and cost-effectively — improve testing accuracy.
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New discovery may change how dexamethasone is prescribed for some COVID-19 patients
New insights into the way the body distributes dexamethasone could mean that patients with high blood sugar may see diminished effects.
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Study finds surprising diversity in early child care
A new study of kindergarteners in one Midwestern state identified seven different pathways the children took in their early education and care before arriving at school.The researchers were surprised by the diverse experiences that kids brought with them to kindergarten: While some received care only in their home or mainly in a child care center, others switched back and forth between different t
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Could SARS-CoV-2 evolve resistance to COVID-19 vaccines?
Similar to bacteria evolving resistance to antibiotics, viruses can evolve resistance to vaccines, and the evolution of SARS-CoV-2 could undermine the effectiveness of vaccines that are currently under development, according to a paper published November 9 in the open-access journal PLOS Biology by David Kennedy and Andrew Read from Pennsylvania State University, USA. The authors also offer recomm
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Rise of the relationship herbivore — Japanese increasingly single, disinterested in dates
In 2015 in Japan, 1 in 4 women and 1 in 3 men in their 30s were single, and half of the singles say they are not interested in heterosexual relationships. Public health experts at the University of Tokyo found that those who are disinterested in relationships are more likely to have lower incomes and less education than their romantically minded peers, potentially pointing towards socioeconomic fa
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A first glimmer of hope for a Covid vaccine
A preventive drug looks promising, but the virus battle is far from over
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Watch: Apple Expected to Unveil New Laptops Today
The company will hold a media event at 10 am PST to announce the debut of Apple-made silicon in its computers.
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First COVID-19 Vaccine Doses To Go To Health Workers, Say CDC Advisers
A team of independent advisers to the Centers for Disease Control and Prevention has a science-based outline for deploying a vaccine when it's ready. The goal is to stop deaths and viral spread fast. (Image credit: Go Nakamura/Getty Images)
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Is a Negative COVID-19 Test Result Truly Negative?
If your coronavirus test came back negative, you might not be out of the woods just yet. The trustworthiness of a negative result depends on the type of test you took, when you tested, and how much contact you've had with other people.
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Biden calls for major investments into carbon removal tech
President-elect Joe Biden wasted little time setting a new tone on climate change. On Sunday, one day after major outlets called the presidential election for the former vice president, the Biden-Harris transition team released documents laying out the incoming administration's early priorities, including a blueprint for "tackling the climate crisis. " Most of the details were drawn directly from
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Taking action for the common good
In 1979, a federally commissioned study led by meteorology pioneer and MIT professor Jule Charney helped alert the world to the processes driving global warming—at the time, a looming but not yet imminent threat. Today, climate change is no longer a challenge for some distant future; it is a present and accelerating crisis requiring swift, far-reaching action. There is room and reason for every o
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Covid testing, MIT style
MELANIE GONICK Seniors arriving on campus for the fall term headed to MIT's custom-designed covid testing trailer, which lets caregivers swab noses using gloves protruding through height-adjustable panels. On August 31, MIT Medical administered over 2,700 tests—more than many states did that day—and topped that with a record 4,979 tests on September 14. Of the 22,176 tests given at MIT between Au
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The Deafening Silence of Republican Leaders
The waiting is over. Now comes … the waiting. The first stage of the presidential interregnum, from Tuesday night through Saturday, was the slow but inexorable march toward Joe Biden being declared the winner of the presidential race. No one knew quite when that would happen, but there was an objective end point: whenever enough votes were counted for the outcome to be clear. The second stage is
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BioNTech and Pfizer raise hopes with breakthrough Covid-19 vaccine
Positive trial data is milestone for experimental products using new mRNA technology
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How a communist physics teacher flattened the COVID-19 curve in southern India
In Kerala state, health minister K. K. Shailaja is fighting to stem a new surge
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Japanese increasingly single, disinterested in dating: study
In Japan, the proportion of the population who are single has increased dramatically in the past three decades. In 2015, one in four women and one in three men in their 30s were single, and half of the singles say they are not interested in heterosexual relationships. Public health experts at the University of Tokyo found that those who are disinterested in relationships are more likely to have lo
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Coming out as bisexual linked to smoking risk
Being bisexual is the identity most associated with smoking, especially around the time of coming out, research finds. For many years, lesbian, gay, bisexual , and other non-heterosexual (LGB+) folks have been known to be more likely to smoke than their straight counterparts. The new study paints a more precise picture by looking at LGB+ identities separately and over time. Published in the journ
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How memorable melodies can make your research sing
Nature, Published online: 09 November 2020; doi:10.1038/d41586-020-03175-7 Writing songs for open-mic sessions at a Boston bar helped scientist-songwriter Saurja DasGupta to communicate his research more confidently.
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What Pfizer's landmark COVID vaccine results mean for the pandemic
Nature, Published online: 09 November 2020; doi:10.1038/d41586-020-03166-8 Scientists welcome the first compelling evidence that a vaccine can prevent COVID-19. But questions remain about how much protection it offers, to whom and for how long.
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Scientists Are Thrilled About President-Elect Biden
New Chapter Vice President Joe Biden is now the new president-elect, and scientists are thrilled about the notion of having a president who actually takes the threats of climate change and COVID-19 seriously. "Our long national nightmare is over," University of Wisconsin Law School bioethicist Alta Charo told Nature , quoting former President Gerald Ford. "I couldn't say it any better than that."
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Study suggests greater social support linked to lower diabetes distress
Perceived lack of support from family and friends affects a patient's ability to manage type 2 diabetes, according to a study published in The Journal of the American Osteopathic Association.
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Implantable sensor could measure bodily functions — and then safely biodegrade
Sensors that monitor a patient's condition during and after medical procedures can be expensive, uncomfortable and even dangerous. Now, an international team of researchers has designed a highly sensitive flexible gas sensor that can be implanted in the body — and, after it's no longer needed, safely biodegrade into materials that are absorbed by the body.
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Biden has a bold agenda, but a divided Congress could constrain him
The new president will likely cancel a host of Trump executive orders
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Why Haven't We Found Alien Life? Blame Our Closed Minds
Are we looking for life in the wrong places, in the wrong way? Would we recognize the signs? Why out there ideas may point the way to E.T.
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Coronavirus Business Update: Biden lays out plans for tackling virus
US president-elect urges caution over potential new vaccine, saying other actions are essential
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McDonald's Is Making a Huge, High Tech Push Into Fake Meats
McPlant Fast food chain McDonald's is making a huge push into plant-based foods with a "platform" it's calling McPlant . New menu items based on it, including a sandwich, will be made available next year, according to USA Today . "McPlant is crafted exclusively for McDonald's, by McDonald's," Ian Borden, McDonald's international president, said during a Monday meeting with investors. "In the futu
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Modern Approaches to qPCR
Download this ebook to learn how updated qPCR instruments provide optimal thermal performance and data connectivity!
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Clinicians who prescribe unnecessary antibiotics fuel future antibiotic use
Receipt of antibiotics for acute respiratory infections makes it more likely that patients and their families will seek care and receive antibiotics for future respiratory viral infections. In the year after their visit, patients randomly assigned to clinicians who prescribed more antibiotics got 15 percent more antibiotics for viral respiratory infections compared with patients seen by clinicians
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Key to piercing harmful bacteria's armor
Researchers have identified a new bacterial protein that assists in delivering components to the outer membrane of the Gram-negative bacterium Escherichia coli.
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Remote learning adds pressure for teachers who work second shift as mothers
The transition to remote learning coupled with an unequal distribution of second-shift responsibilities has placed teachers who are also mothers under immense stress, according to new research.
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Trees set sixth-graders up for success
The transition to middle school is undeniably tough for many sixth-graders, even in the best of times. Mounting academic demands, along with changes in peer dynamics and the onset of puberty, result in a predictable and sometimes irreversible slump in academic performance. A new study suggests an unexpected but potentially potent remedy: trees.
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The ecology of crop pests
Ecological theory provides insights on pesticide use in agriculture
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Researchers examine if online physician reviews indicate clinical outcomes
Dr. Atanu Lahiri and Dr. Zhiqiang Zheng studied the relationship between online reviews of physicians and their patients' actual clinical outcomes. They wanted to know how much consumers can rely on the reviews, specifically in regard to chronic-disease care.
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New 'genomic' method reveals atomic arrangements of battery material
Scientists have developed a new way to decipher the atomic-level structure of materials based on data gleaned from ground-up powder samples. They describe their approach and demonstrate its ability to solve the structure of a material that shows promise for shuttling ions through sodium-ion batteries.
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Researchers discover bacterial DNA's recipe for success
Biomedical engineers have developed a way of modeling how potentially beneficial packages of DNA called plasmids circulate and accumulate through a complex environment that includes many bacterial species. The researchers hope that their new model will lay the groundwork for others to better model and predict how important traits such as antibiotic resistance in pathogens or metabolic abilities in
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Electrified magnets: Researchers uncover a new way to handle data
The properties of synthesized magnets can be changed and controlled by charge currents as suggested by a study and simulations conducted by physicists. The team reports on how magnets and magnetic signals can be coupled more effectively and steered by electric fields. This could result in new, environmentally friendly concepts for efficient communication and data processing.
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Half-a-billion year old microfossils may yield new knowledge of animal origins
When and how did the first animals appear? Science has long sought an answer. Researchers have now jointly found, in Greenland, embryo-like microfossils up to 570 million years old, revealing that organisms of this type were dispersed throughout the world.
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BioNTech's Covid vaccine: a shot in the arm for Germany's Turkish community
Couple who set up and run firm are children of long-maligned 'guest workers' from Turkey Coronavirus – latest updates See all our coronavirus coverage When the German biotechnology company BioNTech picked a street called An der Goldgrube or At the Goldmine in the western city of Mainz for its headquarters, the couple behind it could not have predicted how prophetic the address would turn out to b
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Study confirms spit testing may help doctors diagnose concussions
Doctors may soon be able to more accurately diagnose concussions by measuring the number of certain molecules in a person's saliva, according to Penn State College of Medicine researchers. The results of a recent clinical study confirmed that a patient's spit may be used to aid concussion diagnosis in a non-invasive, non-biased fashion.
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Rapid test shows 'solid performance' for diagnosing infection around joint implants
The recently FDA-authorized alpha-defensin lateral flow test is a highly accurate, ten-minute test for diagnosis of periprosthetic joint infection (PJI) – a serious and costly complication of total joint replacement, reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
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Bringing drugs to the brain with nanoparticles to treat neurodegenerative diseases
Researchers have shown that nanoparticles could be used to deliver drugs to the brain to treat neurodegenerative diseases.
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The CDC released a COVID-19 test knowing it had a high failure rate
Children have a lower immune response to the coronavirus. (Kelly Sikkema/) It's been a big week for coronavirus news. The US saw record-breaking numbers of COVID-19 infections, with single-day numbers crossing 100,000 several times over the course of the week. Pfizer announced this morning that their coronavirus vaccine is 90 percent effective based on initial trial results, though importantly th
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Sample Processing During a Pandemic
Download this ebook to learn how clinical laboratories adapt to handle large-scale sample accessioning and processing!
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Antiferromagnets are suitable for dissipationless nanoelectronics, contrary to current theories
Sometimes combinations of different things produce effects that no one expects, such as when completely new properties appear that the two combined parts do not have on their own. Dr. Libor Šmejkal from Johannes Gutenberg University Mainz (JGU) found such an unexpected property: He combined antiferromagnetic substances with non-magnetic atoms and found that, contrary to the current doctrine, a Hal
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Half-billion-year-old microfossils may yield new knowledge of animal origins
When and how did the first animals appear? Science has long sought an answer to this question. Uppsala University researchers and colleagues in Denmark have now jointly found, in Greenland, embryo-like microfossils up to 570 million years old, revealing that organisms of this type were dispersed throughout the world. The study is published in Communications Biology.
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Newly discovered fossil shows small-scale evolutionary changes in an extinct human species
Males of the extinct human species Paranthropus robustus were thought to be substantially larger than females — much like the size differences seen in modern-day primates such as gorillas, orangutans and baboons. But a new fossil discovery in South Africa instead suggests that P. robustus evolved rapidly during a turbulent period of local climate change about 2 million years ago, resulting in ana
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Bringing drugs to the brain with nanoparticles to treat neurodegenerative diseases
Researchers have shown that nanoparticles could be used to deliver drugs to the brain to treat neurodegenerative diseases.
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Unsettling Robot Grips Like an Elephant's Trunk
Robo-Dumbo A team of scientists built a tentacle-like robot gripper that they say is more sensitive than a conventional claw or hand-shaped machine — because it wraps around and delicately constricts objects like a python or an elephant's trunk. Modeling an elephant's complex musculature allows it to snugly grip delicate or hard-to-reach objects, according to a press release , in a new, gentler p
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Maunakea telescopes confirm first brown dwarf discovered by radio observations
A collaboration between the LOw Frequency ARray (LOFAR) radio telescope in Europe, the Gemini North telescope, and the NASA InfraRed Telescope Facility (IRTF), both on Maunakea in Hawai'i, has led to the first direct discovery of a cold brown dwarf from its radio wavelength emission. Along with paving the way for future brown dwarf discoveries, this result is an important step towards applying rad
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Young survivors of acute myeloid leukemia have long-term complications from treatment
Adolescent and young adult (AYA) patients treated for acute myeloid leukemia (AML) have a high risk of developing several long-term health complications after treatment, a study led by UC Davis Comprehensive Cancer Center researchers has found. The most common complications were cardiovascular, endocrine and respiratory diseases. The complications – known as late effects – were more present among
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Study finds evidence of neurobiological mechanism for hallucinations and delusions
A new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found evidence of a potential neurobiological mechanism for hallucinations and delusions that fits within the hierarchical model of psychosis and can explain their clinical presentation.
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Genetic disposition protects immune system from aging
A genetic disposition that plays a role in the development of the heart in the embryo also appears to play a key role in the human immune system. This is shown by a recent study led by the University of Bonn (Germany). The study is published in the journal Nature Immunology.
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New study defines life cycle of a destructive plant pathogen 142 years after its discovery
"Using confocal and electron microscopic imaging, we provide compelling evidence to support the proposed life cycle of P. brassicae, making it more convincing and acceptable to the community," explained Liu. "Notably, and most surprisingly, we discovered the existence of a sexual life stage of P. brassicae, starting from the fusion of two secondary zoospores within the infected epidermal cells."
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You drive like a girl: Study shows gender bias in perceptions of ride-sharing performance
While digital brokerages provide a more efficient method for the exchange of goods and services and an improved way for consumers to voice their opinions about the quality of work they receive, bias and discrimination can emerge as part of the review process, according to Notre Dame research.
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Global analysis of forest management shows local communities often lose out
Maintaining forest cover is an important natural climate solution, but new research shows that too often, communities lose out when local forest management is formalised.The new study published today in Nature Sustainability, led by Dr Johan Oldepkop at The University of Manchester and Reem Hajjar at Oregon State University, is based on 643 case studies of community forest management (CFM) in 51 d
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A randomized clinical trial of Greek High Phenolic Early Harvest Extra Virgin Olive Oil in mild cognitive impairment: the MICOIL pilot study
Greek researchers and clinicians investigated for the first time the effect of High Phenolic Early Harvest Extra Virgin Olive Oil (HP-EH-EVOO) versus Moderate Phenolic (MP-EVOO) and Mediterranean Diet (MeDi) as a therapeutic pharmaceutical natural compound for older adults with amnestic Mild Cognitive Impairment (aMCI). Amnestic MCI is usually a prodromal condition of Alzheimer's disease (AD) and
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RUDN University biologist found sex differences in inflammatory reactions in rat pups
A biologist from RUDN University studied the development of the immune response in prepubertal male and female animals. According to her, the severity and mortality of infectious and inflammatory diseases at this age depend not on the sex hormones, but mainly on the chromosome set or karyotype.
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Clinicians who prescribe unnecessary antibiotics fuel future antibiotic use
Receipt of antibiotics for acute respiratory infections makes it more likely that patients and their families will seek care and receive antibiotics for future respiratory viral infections. In the year after their visit, patients randomly assigned to clinicians who prescribed more antibiotics got 15 percent more antibiotics for viral respiratory infections compared with patients seen by clinicians
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Yin and Yang: Two signaling molecules control growth and behavior in bacteria
Bacteria are considered to be true experts in survival. Their rapid adaptive response to changing environmental conditions is based, among other things, on two competing signaling molecules. As the 'Yin and Yang' of metabolic control they decide on the lifestyle of bacteria, as reported by researchers from the University of Basel. The new findings also play a role in the context of bacterial infec
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Researchers find key to piercing harmful bacteria's armor
Bacteria are single-celled organisms that are essential to human health, both in our environment and inside our own bodies. However, certain bacterial species can make us sick.
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Ecological theory provides insights on pesticide use in agriculture
As agriculture in the United States evolves, it's becoming more intensive and less complex. That means larger fields, more cropland and less crop diversity with fewer crops in rotation.
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Yin and Yang: Two signaling molecules control growth and behavior in bacteria
Bacteria are considered to be true experts in survival. Their rapid adaptive response to changing environmental conditions is based, among other things, on two competing signaling molecules. As the 'Yin and Yang' of metabolic control they decide on the lifestyle of bacteria, as reported by researchers from the University of Basel. The new findings also play a role in the context of bacterial infec
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Remote learning adds pressure for teachers who work second shift as mothers
The transition to remote learning coupled with an unequal distribution of second-shift responsibilities has placed teachers who are also mothers under immense stress, according to new University at Buffalo research.
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Researchers find key to piercing harmful bacteria's armor
Bacteria are single-celled organisms that are essential to human health, both in our environment and inside our own bodies. However, certain bacterial species can make us sick.
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Ecological theory provides insights on pesticide use in agriculture
As agriculture in the United States evolves, it's becoming more intensive and less complex. That means larger fields, more cropland and less crop diversity with fewer crops in rotation.
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Trees set sixth-graders up for success
The transition to middle school is undeniably tough for many sixth-graders, even in the best of times. Mounting academic demands, along with changes in peer dynamics and the onset of puberty, result in a predictable and sometimes irreversible slump in academic performance.
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Humlor kan rädda skördarna vid förändrat klimat
Skörden minskade kraftigt i bestånd som stressats av torka, bladlöss eller både och. Bevattning hjälpte inte de redan stressande plantorna. Men oavsett stressnivå åstadkom humlor en rejäl skördeökning, visar forskare vid SLU som undersökt hur odling av åkerböna kan påverkas av ett förändrat klimat. Bevattning av en bladlusangripen gröda under ett torrår gav i princip ingen merskörd alls, vilket b
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Pfizer's and BioNTech's vaccine is the start of the end of the pandemic
Its 90% effectiveness is as good as it gets, and bodes well for other vaccines. But getting them quickly to the right people will be hard
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