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Toward a better multi-model ensemble prediction of East Asian and Australasian precipitation during non-mature ENSO seasons
7dScientific Reports, Published online: 20 November 2020; doi:10.1038/s41598-020-77482-4
Positron annihilation localization by nanoscale magnetization
7dScientific Reports, Published online: 20 November 2020; doi:10.1038/s41598-020-76980-9
Polyrhythmic foraging and competitive coexistence
7dScientific Reports, Published online: 20 November 2020; doi:10.1038/s41598-020-77483-3
A simple score derived from bone marrow immunophenotyping is important for prognostic evaluation in myelodysplastic syndromes
7dScientific Reports, Published online: 20 November 2020; doi:10.1038/s41598-020-77158-z
Plant health status effects on arbuscular mycorrhizal fungi associated with Lavandula angustifolia and Lavandula intermedia infected by Phytoplasma in France
7dScientific Reports, Published online: 20 November 2020; doi:10.1038/s41598-020-77240-6
Two-year outcomes of intravitreal aflibercept in a Swiss routine treat and extend regimen for patients with neovascular age-related macular degeneration
7dScientific Reports, Published online: 20 November 2020; doi:10.1038/s41598-020-76354-1
Induction of TOC and TIC genes during photomorphogenesis is mediated primarily by cryptochrome 1 in Arabidopsis
7dScientific Reports, Published online: 20 November 2020; doi:10.1038/s41598-020-76939-w
Effects of precipitation and temperature on precipitation use efficiency of alpine grassland in Northern Tibet, China
7dScientific Reports, Published online: 20 November 2020; doi:10.1038/s41598-020-77208-6
Are humans cruel by nature?
7dHow have humans managed to accomplish significantly more than any other species on the planet? Historian Rutger Bregman believes the quality that makes us special is that we "evolved to work together and to cooperate on a scale that no other species in the whole animal kingdom has been able to do." Pushing back against the millennia-old idea that humans are inherently evil beneath their civilized
Do digital contact tracing apps work? Here's what you need to know.
7dIn the early days of the covid-19 pandemic, several competing projects launched around a deceptively simple concept: your phone could alert you if you'd crossed paths with someone who later tested positive. One system for these exposure notifications quickly caught on. It was designed, in an improbable act of cooperation, by Apple and Google, which released the first version in May . How do the A
On Thin Ice: Climate Change Is Making Winter More Dangerous
7dA new study found that winter drownings are increasing sharply in warmer parts of the Northern Hemisphere.
Kræftpatienter med alvorlig psykisk lidelse skal have bedre behandlingsforløb
7dKræftens Bekæmpelse har tildelt et projekt for kræftpatienter med svære psykiske lidelser over en halv mio. kr. Pengene skal gå til, at forskere kan analysere patienternes forhold og dermed skabe bedre forhold for både patienter og læger.
Now we need to vaccinate the world
7dEnsuring equitable distribution is essential to defeating coronavirus
Oxford-vaccine overgår Pfizer og skal ikke fryses til -70 grader
7d208 ud af 209 forsøgspersoner dannede neutraliserende antistoffer i Oxford Universitys fase-2-studie af en mulig corona-vaccine.
Armering i Langelandsbroen er tæret igennem. Forstærkning på vej
7dPLUS. Mange års saltning har fået forspændingskabler til at ruste, og sidste år fandt Vejdirektoratet et gennemtæret kabel.
Dansk studie sår tvivl om seneste årtiers forskning i blærebetændelse
7dMed verdens første grisemodel for blærebetændelse sår danske forskere tvivl om de seneste årtiers forskning på området. Og så baner forskningen vej for nye behandlingsformer ifølge lægen bag studiet.
China's new coal plants risk 2060 climate target: researchers
7dChina must stop building new coal power plants and ramp up its wind and solar capacity if it wants to become carbon neutral by 2060, researchers said Friday.
Who should get a covid-19 vaccine first?
7dThis article was originally published on Undark . Read the original article . If the book of nature is written in the language of mathematics, as Galileo once declared, the covid-19 pandemic has brought that truth home for the world's mathematicians, who have been galvanized by the rapid spread of the coronavirus. So far this year, they have been involved in everything from revealing how contagio
Australia signals shift away from climate credit 'cheating'
7dAustralia's prime minister said the country may no longer rely on a much-criticised accounting tactic to meet its emissions targets, stepping away from an approach international partners had labelled "cheating".
Rederier sætter ny kurs: Skibe skal skifte til nye brændstoffer, sol og sejl
7dPLUS. De fleste af fremtidens store skibe vil stadig have gigantiske stempelmotorer i maskinrummet. Men løsninger baseret på autonomi, bæredygtige brændstoffer, vind og sol skal gøre skibene klimavenlige.
UK coronavirus live: Christmas household mixing could lead to tens of thousands more cases, expert warns
7dLatest updates: Prof Sir David Spiegelhalter warns relaxing restrictions over Christmas could lead to a spike in cases and deaths NHS prepares dozens of Covid mass vaccination centres Unions call for frontline workers to be prioritised for vaccine Spending row as Sunak puts squeeze on public sector salaries Bullying inquiry 'found evidence Priti Patel broke ministerial code' Coronavirus – latest
Simple, no-cost ways to help the public care for the commons
7dResearchers from University of Wisconsin-Madison, New York Institute of Technology, University of Iowa, and Cornell University published a new paper in the Journal of Marketing that examines whether it is possible to make people feel as if the property is theirs—a feeling known as psychological ownership—and how this affects their stewardship behaviors.
The microbiome of Da Vinci's drawings
7dThe work of Leonardo Da Vinci is an invaluable heritage of the 15th century. From engineering to anatomy, the master paved the way for many scientific disciplines. But what else could the drawings of Da Vinci teach us? Could molecular studies reveal interesting data from the past? These questions led an interdisciplinary team of researchers, curators and bioinformaticians, from both the University
The microbiome of Da Vinci's drawings
7dThe work of Leonardo Da Vinci is an invaluable heritage of the 15th century. From engineering to anatomy, the master paved the way for many scientific disciplines. But what else could the drawings of Da Vinci teach us? Could molecular studies reveal interesting data from the past? These questions led an interdisciplinary team of researchers, curators and bioinformaticians, from both the University
Climate change and 'atmospheric thirst' to increase fire danger and drought in NV and CA
7dClimate change and a "thirsty atmosphere" will bring more extreme wildfire danger and multi-year droughts to Nevada and California by the end of this century, according to new research from the Desert Research Institute (DRI), the Scripps Institution of Oceanography at the University of California, San Diego, and the University of California, Merced.
College students are less food insecure than non-students
7dCollege students are significantly less likely to be food insecure than non-students in the same age group, according to a new study from the University of Illinois.
Spill-over effects show prioritising education of very poorest improves attainment of all
7dInternational development projects that target the education of the world's very poorest children and marginalised girls also significantly improve other young people's attainment, according to new research that suggests such initiatives should become a priority for international aid.
Artificial intelligence and satellite technologies reveal detailed map of air pollution across UK
7dA novel method that combines artificial intelligence with remote sensing satellite technologies has produced the most detailed coverage of air pollution in Britain to date.
Derfor er champagne og østers et godt makkerpar
7dPLUS. Og hvorfor er skinke og ost en fremragende kombination? Det har tre forskere fra Københavns Universitet nu en videnskabelig forklaring på.
Databaseformænd: Styrk det tværsektorielle lungesamarbejde
7dBedre sektorsamarbejde kan løfte behandlingen af store grupper af lungepatienter som KOL- og astmapatienter, mener formændene for henholdsvis lungecancer-, KOL- og astmaregistret.
Computer vision can estimate calorie content of food at a glance
7dA neural network fed with 300,000 photographs of meals and information from 70,000 recipes can now estimate the calorie content of food from a photo
Ancient parasites in a titanosaur's bones made it look like a zombie
7dThe first discovery of parasites in a dinosaur bone reveals some of the oldest evidence of bone disease, which left a titanosaur with open wounds
Potent new antifungal discovered in the microbiome of marine animals
7dA new antifungal compound that is effective against multidrug-resistant fungi has been isolated from bacteria living in filter-feeding marine animals called sea squirts
Ebola outbreak in the DRC ended thanks to vaccine distribution efforts
7dThe 11th outbreak of Ebola virus in the Democratic Republic of the Congo has ended after six months. Ultracold devices for vaccine distribution played a key role, and could help with the coronavirus pandemic
Covid-19 news: Socialising at Christmas poses 'substantial risks'
7dThe latest coronavirus news updated every day including coronavirus cases, the latest news, features and interviews from New Scientist and essential information about the covid-19 pandemic
Very hangry caterpillars could help reveal genetic basis of aggression
7dMonarch caterpillars get more aggressive when they are hungry, resulting in them headbutting and lunging at other caterpillars in an attempt to secure food
Your eyes can reveal your decisions before you've even made them
7dDeciding whether to complete a task that requires physical effort can trigger a change in your pupil size and brain activity, and these signals can reveal your ultimate choice
Capuchin monkeys spotted eating infant in rare act of cannibalism
7dCannibalism is extremely rare among the primates living in the Americas – but some capuchin monkeys have now been spotted eating a dead infant
California's latest erosion of gig worker rights could be going global
7dA measure passed in California removes many employment rights for gig workers. Similar rules could soon come to a place near you, writes Annalee Newitz
Our supposed earliest human relative may have walked on four legs
7dThe femur of Sahelanthropus tchadensis, generally regarded as the oldest known hominin, has finally been scientifically examined. The results suggest it walked on four legs, so may not actually be a close human relative at all
Magnetic spray turns objects into mini robots that can deliver drugs
7dA glue-like magnetic spray can turn objects, such as pills, into mini robots that can be controlled by magnets and navigated through the body
AI that can diagnose tinnitus from brain scans may improve treatment
7dTinnitus is usually diagnosed by a hearing test, by self-reporting or based on a subjective questionnaire, but now an AI can make a more objective assessment from brain scans
Warehouse robots upgraded to make packing decisions 350 times faster
7dRobotic arms for packing boxes in warehouses work out which path to take more than 350 times faster when using a neural network that predicts how quickly they can safely transport items
Is Boris Johnson's climate plan enough for the UK to hit net zero?
7dThe UK's new 10-point climate plan is the first big step towards meeting a target of net zero emissions by 2050, but it doesn't have the funding to make new climate policies a reality
Portable device uses solar power to sterilise medical equipment
7dA solar-powered device can generate enough high-pressure steam to sterilise medical instruments, and could be used by medics in resource-limited areas
What are mRNA vaccines and how useful will they be?
7dCoronavirus vaccines being developed by Pfizer and Moderna could be the first mRNA vaccines to get approval. Here's how these vaccines work and how might they change the world
We can't be certain the coronavirus vaccines will stop the pandemic
7dHeadlines about safe and effective covid-19 vaccines seem simple, but the truth is that the trials tell us far less than we assume about who will benefit from a vaccine
US Navy's huge uncrewed robot ship has journeyed through Panama Canal
7dAn uncrewed vessel that can carry 540 tonnes of cargo and cruise at 65 kilometres per hour has just become the first robotic vessel to pass through the Panama Canal
Toads on tropical islands are rapidly shrinking as they evolve
7dToads that were introduced to two tropical islands in the 1920s are now a third smaller than their mainland peers, possibly a sign of remarkably rapid evolution
UK 10-point climate plan bans new petrol and diesel car sales by 2030
7dThe UK will ban sales of new petrol and diesel cars by 2030, ten years earlier than planned, under prime minister Boris Johnson's ten-point plan for more ambitious action on climate change
The sale of the duelling dinosaurs fossil may be bad news for science
7dThe Duelling Dinosaurs are a fossil hunter's dream. After a decade-long saga, a museum has now purchased the specimen but that may do palaeontology more harm than good, says Riley Black
We've seen a planet being born while its star is still forming
7dAstronomers may have seen a Jupiter-like planet begin to form while its host star is still growing, proving a long-held theory about planet formation
Moderna coronavirus vaccine trial produces best results yet
7dPfizer BioNTech FDA
Early results suggest the Moderna vaccine is even more effective than the Pfizer vaccine, including in older people, boosting hopes that we might end up with several vaccines against covid-19
Repeated radio bursts from nearby star suggest such signals are common
7dThe first source of fast radio bursts inside our galaxy is also producing much weaker signals, suggesting FRBs could be common throughout the universe
Heidi Larson interview: How to stop covid-19 vaccine hesitancy
7dPfizer Covid Vaccine FDA
Heidi Larson at the Vaccine Confidence Project explains how we can tackle public hesitancy around the first covid-19 vaccines
Your own sweat could be used to produce a natural antiperspirant
7dMinerals found naturally in sweat may be able to act as an antiperspirant by clogging your sweat ducts
Three-metre-long dinosaur may have swum across a wide ocean
7dA fossil duck-billed dinosaur has been found in Africa for the first time, suggesting these dinosaurs could cross expanses of ocean to reach new lands
How-to guide for CPR in space may help treat astronaut cardiac arrest
7dNobody has experienced cardiac arrest in space yet, but such a medical emergency might occur in future – and now we have some tips for how to handle the problem
The covid-19 pandemic has reignited questions about population size
7dA pandemic assisted by our incursions into nature has given questions about human population size a renewed focus, but advocates for limiting population also have questions to answer
Et tarm-molekyle kan reducere effekt af diabetesbehandling
7dForskere fra blandt andet Sverige har fundet ud af, at effekten af metformin kan blokeres af et molekyle, som nogle bakterier i tarmene producerer.
JAMA promotes the false equivalence of 'focused protection'
7dOn November 11 JAMA hosted a podcast with Dr. Jay Bhattacharya, one of the authors of the Great Barrington Declaration. The discussion included factual inaccuracies and created a false equivalence between the fringe idea of 'focused protection' versus ongoing public health efforts to restrain community spread. The post JAMA promotes the false equivalence of 'focused protection' first appeared on
Hur finner vi tid för fysisk aktivitet i vardagslivet?
7dUndrar du också hur du ska få till fysisk aktivitet i ditt vardagsliv? Varför inte lyssna på en inspirationsföreläsning där neuroforskaren Martina Svensson berättar om hur fysisk aktivitet påverkar hjärnhälsa. Nyfiken på mer? Då kan du lyssna på ett efterföljande panelsamtal där forskare som alla studerat fysisk aktivitet utifrån sina expertområden diskuterar hur vi konkret kan göra för att öka vå
Scientists race to find 'warm' Covid vaccine to solve issue of cold storage
7dPfizer BioNTech FDA
With potential injectable vaccines estimated to be out of reach for two-thirds of world's population, scientists hope to find less-heat-sensitive formulations News that one of the potential coronavirus vaccines had at least a 90% efficacy rate was a "victory for science", said K Srinath Reddy, a cardiologist and president of the Public Health Foundation of India. But it meant little to his countr
China has given almost a million people experimental Covid vaccine, says company
7dPfizer BioNTech FDA
Sinopharm chairman claims there has not been a single case of infection after inoculation of officials, students and workers heading overseas Almost a million people in China have taken an emergency Covid-19 vaccine that is still in its testing phase, the company that developed the vaccine has said. Chinese authorities released the vaccine, developed by China National Pharmaceutical Group (Sinoph
Social Fragmentation Resembles The Melting of Ice – And We May Be Near Tipping Point
7dSociety's breakdown is mirrored in nature.
Photos of the Week: Tiger Check, Spanish Fog, Duck Shields
7dThe Bailong Elevator in China, continued wildfires in California, hats on display in Russia, dancers in Australia and Italy, damaging storms in Honduras and the Philippines, a surge in COVID-19 cases in the U.S., Christmas preparations during a pandemic, a rocket launch to the International Space Station, and much more
Medical technology gives healthcare a shot in the arm
7dDoctors have been spurred by Covid-19 to experiment with tech but it is not a cure-all
Limited access to buprenorphine restricts resident physicians treating opioid abusers
7dA University of South Florida Health-led survey of resident physicians in Florida indicates they are interested in treating opioid addiction but face barriers to offering patients treatment using buprenorphine, an FDA-approved medication shown to successfully decrease opioid use, overdose events, and deaths associated with opioids. Many states have reported increased deaths from opioids since the
Simple, no-cost ways to help the public care for the commons
7dBy fostering visitors' individual feelings of ownership of a public resource, visitors will feel more responsible for it, take better care of it, and donate more time and money for its benefit.
Near-infrared probe decodes telomere dynamics
7dA new synthetic probe offers a safe and straightforward approach for visualizing chromosome tips in living cells. The probe was designed by scientists at the Institute for Integrated Cell-Material Science (iCeMS) and colleagues at Kyoto University, and could advance research into aging and a wide range of diseases, including cancers. The details were published in the Journal of the American Chemic
Coaching sales agents? Use AI and human coaches
7dInstead of simply applying an AI coach to the entire workforce, managers ought to prudently design it for targeted sales agents.
CHOP researchers reverse severe lymphatic disorder in patient with Noonan syndrome
7dResearchers at Children's Hospital of Philadelphia (CHOP) have resolved a severe lymphatic disorder in a girl with Noonan Syndrome that had led to upper gastrointestinal bleeding, fluid collection around the lungs, and numerous surgeries that had been unable to resolve her symptoms. By identifying a genetic mutation along a pathway related to lymphatic vessel development and function, the research
The microbiome of Da Vinci's drawings
7dThe microbiome study of seven drawings from Leonardo Da Vinci reveals that conservation work, geographical location, and past contaminations leave invisible traces on drawings despite their optimal storage conditions: a novel aspect of art objects that could be monitored to establish a bioarchive of our artistic heritage.
Study evaluates new World Health Organization Labor Care Guide for maternity care providers
7dThe World Health Organization developed the new Labor Care Guide to support clinicians in providing good quality, women-centered care during labor and childbirth. In a study published in Birth, researchers evaluated the usability, feasibility, and acceptability of the new Labor Care Guide for maternity care providers in six countries.
Secret ingredients behind the breakthrough Covid vaccines
7dModerna and BioNTech-Pfizer's shots use same mRNA technology but with key differences
The Mystery of This Strange, Blue Nebula May Have Finally Been Solved
7dA 'missing link' of star mergers.
7d
Researchers recommend more transparency for gene-edited crops
7dTo gain trust, researchers recommend a wide-ranging coalition that would provide more transparency on the presence and use of gene editing in food supplies.
Can animals use iridescent colors to communicate?
7dA new paper sheds light on the colorful world of animal communication, highlighting the challenges of studying accurately how iridescent colors work in nature.
Mikroorganismer i sengen kan måske gavne børns sundhed
7dI det største studie af sin slags har forskere fra Københavns Universitet i samarbejde med…
Adfærdsforskning rakte direkte ind i corona-ramte Rom
7dTo forskere fra Økonomisk Institut har modtaget takkebrev fra borgmesteren i Rom for deres indsats…
How will future humans perceive our culture?
7dThis is kinda a weird question, and I probably sound stupid because I don't ever really do anything with futurology, I'm just in this sub because it's an interesting premise. How do you think future humans will perceive our culture? To clarify, by "future humans" I mean humans from thousands of years in the future, when all our current traditions and ways of life have most likely died out, and po
New Magnetic Spray Transforms Objects Into Insect-Scale Robots for Biomedical Applications
7dsubmitted by /u/NineteenSkylines [link] [comments]
A neural network learns when it should not be trusted – "Alexander Amini and his colleagues at MIT and Harvard University developed a quick way for a neural network to crunch data, and output not just a prediction but also the model's confidence level based on the quality of the available data."
7dsubmitted by /u/StcStasi [link] [comments]
Scientists reprogram immune B cells using CRISPR to produce same broadly neutralizing HIV antibodies found in rare HIV patients. These engineered immune cells elicit broad response to HIV in mice, offering hope for vaccine or functional cure against numerous strains of the fast-evolving virus.
7dsubmitted by /u/mvea [link] [comments]
Biomimicry has looked to natural systems to inspire new product designs- now some are turning to Nature to uncover new business models
7dsubmitted by /u/zipsweep [link] [comments]
Another big steel producer turns to solar power "Nucor marks the second major steel manufacturer this fall to turn to solar to power its operation"
7dsubmitted by /u/V2O5 [link] [comments]
NYC-area nuclear plant sale for decommissioning is approved
7dsubmitted by /u/redingerforcongress [link] [comments]
Scientists create diamonds at room temperature in minutes – Both fine jewelry quality and industrial quality
7dsubmitted by /u/izumi3682 [link] [comments]
Big electric trucks and buses are coming. Here's how to speed up the transition. Financing, policy, and private sector tools can fund vehicle costs and new charging infrastructure.
7dsubmitted by /u/altmorty [link] [comments]
Introducing Douglas – Autonomous Digital Human | Digital Domain
7dsubmitted by /u/William9166 [link] [comments]
Solar power stations in space could be the answer to our energy needs
7dsubmitted by /u/altmorty [link] [comments]
Scientists Discover Outer Space Isn't Pitch Black After All
7dsubmitted by /u/Memetic1 [link] [comments]
Molten Salt Reactor using Thorium,it could use spent fuel rods with 90% efficiency lower their half life in half/THorium is more abundant than Uranium and safer
7dsubmitted by /u/gillbeats [link] [comments]
Bose-Einstein condensation superconductivity induced by disappearance of the nematic state – This is the first time a Bose-Einstein condensate has been verified to work as a superconductor.
7dsubmitted by /u/Gari_305 [link] [comments]
CRISPR-based genome editing system treatment destroys cancer cells (in mice) – Researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic manipulation (CRISPR-LNPs).
7dsubmitted by /u/izumi3682 [link] [comments]
Mushroom cultivation produces three times its weight in waste. It's now being turned into burgers and fertiliser
7dsubmitted by /u/MichaelTen [link] [comments]
7d
CRISPR-based genome editing system targets cancer cells and destroys them by genetic manipulation. A single treatment doubled the average life expectancy of mice with glioblastoma, improving their overall survival rate by 30%, and in metastatic ovarian cancer increased their survival rate by 80%.
7dsubmitted by /u/mvea [link] [comments]
Bill Gates Says In-Person Meetings Aren't The 'Gold Standard' Anymore And That 50% Of Business Travel Will Go Away Even After Pandemic
7dsubmitted by /u/auscrisos [link] [comments]
New effective and safe antifungal isolated from sea squirt microbiome
7dBy combing the ocean for antimicrobials, scientists have discovered a new antifungal compound that efficiently targets multi-drug-resistant strains of deadly fungi without toxic side effects in mice.
A pressure sensor at your fingertips
7dResearchers have developed an ultrathin pressure sensor that can be attached directly to the skin. It can measure how fingers interact with objects to produce useful data for medical and technological applications. The sensor has minimal effect on the users' sensitivity and ability to grip objects, and it is resistant to disruption from rubbing. The team also hopes their sensor can be used for the
Livestock plants and COVID-19 transmission [Economic Sciences]
7dPolicy responses to the COVID-19 outbreak must strike a balance between maintaining essential supply chains and limiting the spread of the virus. Our results indicate a strong positive relationship between livestock-processing plants and local community transmission of COVID-19, suggesting that these plants may act as transmission vectors into the surrounding…
Dogmatism manifests in lowered information search under uncertainty [Political Sciences]
7dWhen knowledge is scarce, it is adaptive to seek further information to resolve uncertainty and obtain a more accurate worldview. Biases in such information-seeking behavior can contribute to the maintenance of inaccurate views. Here, we investigate whether predispositions for uncertainty-guided information seeking relate to individual differences in dogmatism, a phenomenon…
Machine-learning iterative calculation of entropy for physical systems [Physics]
7dCharacterizing the entropy of a system is a crucial, and often computationally costly, step in understanding its thermodynamics. It plays a key role in the study of phase transitions, pattern formation, protein folding, and more. Current methods for entropy estimation suffer from a high computational cost, lack of generality, or…
Retinol binding protein 4 primes the NLRP3 inflammasome by signaling through Toll-like receptors 2 and 4 [Immunology and Inflammation]
7dAdipose tissue (AT) inflammation contributes to systemic insulin resistance. In obesity and type 2 diabetes (T2D), retinol binding protein 4 (RBP4), the major retinol carrier in serum, is elevated in AT and has proinflammatory effects which are mediated partially through Toll-like receptor 4 (TLR4). We now show that RBP4 primes…
Modular transient nanoclustering of activated {beta}2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies [Cell Biology]
7dNone of the current superresolution microscopy techniques can reliably image the changes in endogenous protein nanoclustering dynamics associated with specific conformations in live cells. Single-domain nanobodies have been invaluable tools to isolate defined conformational states of proteins, and we reasoned that expressing these nanobodies coupled to single-molecule imaging-amenable tags could..
TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells [Immunology and Inflammation]
7dAntigen-presenting conventional dendritic cells (cDCs) are broadly divided into type 1 and type 2 subsets that further adapt their phenotype and function to perform specialized tasks in the immune system. The precise signals controlling tissue-specific adaptation and differentiation of cDCs are currently poorly understood. We found that mice deficient in…
Event-specific interventions to minimize COVID-19 transmission [Applied Mathematics]
7dCOVID-19 is a global pandemic with over 25 million cases worldwide. Currently, treatments are limited, and there is no approved vaccine. Interventions such as handwashing, masks, social distancing, and "social bubbles" are used to limit community transmission, but it is challenging to choose the best interventions for a given activity….
How rotavirus causes severe gastrointestinal disease
7dUsing intercellular calcium waves, rotavirus amplifies its ability to cause disease beyond the cells it directly infects. This is the first virus identified to activate ADP-mediated intercellular calcium waves.
Artificial intelligence-based tool may help diagnose opioid addiction earlier
7dResearchers have used machine learning, a type of artificial intelligence, to develop a prediction model for the early diagnosis of opioid use disorder.
Long-acting antipsychotic therapy plus cognitive training show promise for schizophrenia
7dScientists have found that the use of long-acting antipsychotic medication combined with the use of cognitive training in group settings led to improved cognition and increased productivity.
Researchers identify features that could make someone a virus super-spreader
7dResearchers used computer-generated models to numerically simulate sneezes in different types of people and determine associations between people's physiological features and how far their sneeze droplets travel and linger in the air. They found that people's features, like a stopped-up nose or a full set of teeth, could increase their potential to spread viruses by affecting how far droplets trav
Predicting forces between oddly shaped nanoparticles
7dMaterials scientists have devised a simplified method for calculating the forces that cause nanoparticles to self-assemble. With this new model and graphical user interface, researchers will be able to make previously impossible predictions about how nanoparticles with a wide variety of shapes will interact with one another. The new method offers opportunities for rationally designing such particl
CLCN6 identified as disease gene for a severe form of lysosomal neurodegenerative disease
7dA mutation in the CLCN6 gene is associated with a novel, particularly severe neurodegenerative disorder. Scientists have now analyzed the effect of a point mutation that was found in three unrelated affected children.
In a First, Scientists Say They've Partially Reversed a Cellular Aging Process in Humans
7dHere's what you need to know.
How the microbiome rouses the body's virus-fighting powers
7dNature, Published online: 18 November 2020; doi:10.1038/d41586-020-03269-2 A molecule on the surface of a common gut microbe helps to activate genes involved in the immune response.
Nemt at udskifte reservedele på ny iPhone: Men kun Apple må gøre det
7dPLUS. Forbrugerrådet Tænk kritiserer den stigende brug af serialisering, hvor enkeltkomponenter låses til serienummeret med software.
Researchers identify features that could make someone a virus super-spreader
7dResearchers used computer-generated models to numerically simulate sneezes in different types of people and determine associations between people's physiological features and how far their sneeze droplets travel and linger in the air. They found that people's features, like a stopped-up nose or a full set of teeth, could increase their potential to spread viruses by affecting how far droplets trav
Predicting forces between oddly shaped nanoparticles
7dMaterials scientists have devised a simplified method for calculating the forces that cause nanoparticles to self-assemble. With this new model and graphical user interface, researchers will be able to make previously impossible predictions about how nanoparticles with a wide variety of shapes will interact with one another. The new method offers opportunities for rationally designing such particl
World Health Organization Rejects Antiviral Drug Remdesivir as Covid-19 Treatment
7dWHO Gilead FDA Covid 19
In a review of several trials, the World Health Organization found that Gilead's drug did not improve survival rates for patients nor did it help them recover.
Giant aquatic bacterium is a master of adaptation
7dThe largest freshwater bacterium, Achromatium oxaliferum, is highly flexible in its requirements, as researchers have now discovered: It lives in places that differ extremely in environmental conditions such as hot springs and ice water. The adaptation is probably achieved by a process which is unique to these bacteria: only relevant genes are enriched in the genomes and transcribed, while others
The secret social lives of giant poisonous rats
7dThe African crested rat is the only mammal known to sequester plant toxins for chemical defense. A new study confirmed that the rabbit-sized rodent licks poison from the bark of Acokanthera schimperi, known as the poison arrow tree, into specialized fur. The researchers also discovered an unexpected social life — the rats appear to be monogamous and may even form small family units with their off
Understanding lung infections in patients with cystic fibrosis
7dFor young people with cystic fibrosis, lung infection with Staphylococcus aureus, MRSA, is common and is treated with antibiotics in the hope that this will prevent a decline in lung function. However there has recently been debate over the role S. aureus plays in CF lung disease. Researchers have used a new model of CF lungs which could be used to make better decisions about future use of antibio
US to shut down famed huge Arecibo space telescope in Puerto Rico jungle
7dArecibo Puerto Rico
The observatory has played a key part in space exploration – and a few movies – but two accidents have rendered the 305m-wide instrument unsafe A huge US space telescope nestled deep in the Puerto Rican jungle will be shut down after suffering two destructive mishaps in recent months, ending 57 years of astronomical discoveries. Operations at the Arecibo observatory, one of the largest in the wor
The Atlantic Daily: The Final Pandemic Surge
7dEvery weekday evening, our editors guide you through the biggest stories of the day, help you discover new ideas, and surprise you with moments of delight. Subscribe to get this delivered to your inbox . SHUTTERSTOCK / PAUL SPELLA / THE ATLANTIC This week brought another round of urgent pandemic updates, both catastrophic and spectacular. Our writers help you process the good and the bad. "Unders
Global map of bees created in conservation first
7dThe data will help protect vital pollinators and could lead to new bee discoveries, say scientists.
Hospitals, Health Care Workers Issue a Call to Arms for Wearing Masks
7dWith the pandemic raging in the U.S., a new ad campaign features frontline medical personnel pleading for everyone to mask up.
The Caribbean islands poisoned by a carcinogenic pesticide
7dOn Martinique and Guadeloupe a pesticide has poisoned the soil and water and caused many cases of prostate cancer.
For The First Time Ever, Scientists Have Created Diamonds in The Lab Without Heat
7dDiamonds in minutes.
Trump's EPA Chief, Andrew Wheeler, Plans 2 Foreign Trips Before Leaving Office
7dAndrew Wheeler, the head of the Environmental Protection Agency, looks to squeeze in two overseas trips in the Trump administration's last days.
Zircon in a meteorite opens the door on Mars' past
7dA meteorite from Mars unexpectedly contains zircons that reveal the planets history. The rock likely comes from one of the solar system's tallest volcanoes. Analyzing the zirconium required smashing some very expensive rock. Just last week, we wrote about one lab's conclusion that water may be a common byproduct in the formation of rocky planets. This week, the same lab has announced that the ver
Climate change and 'atmospheric thirst' to increase fire danger and drought in NV and CA
7dClimate change and a 'thirsty atmosphere' will bring more extreme wildfire danger and multi-year droughts to Nevada and California by the end of this century, according to new research.
Engineered immune cells elicit broad response to HIV in mice, offering hope for vaccine
7dUnlike so many other deadly viruses, HIV still lacks a vaccine. The virus has proven especially tricky to prevent with conventional antibodies, in part because it evolves so rapidly in the body. A solution would require coaxing the body into producing a special type of antibody that can act broadly to defeat multiple strains of the virus at once. Scientists have moved closer to attaining that goal
Breaking the power and speed limit of lasers
7dResearchers have developed a new design of vertical-cavity surface-emitting laser (VCSEL) that demonstrates record-fast temporal bandwidth.
Insights in the search for new antibiotics
7dA collaborative research team published an opinion article that addresses the gap in the discovery of new antibiotics.
First map of bee species around the globe
7dThere are over 20,000 species of bee, but accurate data about how these species are spread across the globe are sparse. However, researchers have now created a map of bee diversity by combining the most complete global checklist of known bee species with the almost 6 million additional public records of where individual species have appeared around the world.
WHO Guideline Development Group advises against use of remdesivir for covid-19
7dThe antiviral drug remdesivir is not suggested for patients admitted to hospital with covid-19, regardless of how severely ill they are, because there is currently no evidence that it improves survival or the need for ventilation, say a WHO Guideline Development Group (GDG) panel of international experts in The BMJ today.
Spill-over effects show prioritising education of very poorest improves attainment of all
7dInternational development projects that target the education of the world's very poorest children also significantly improve other young people's attainment, University of Cambridge research indicates. The findings are based on a study of a programme targeting marginalised girls in Tanzania, which showed the attainment of other boys and girls at these pupils' schools significantly improved through
W.H.O. Rejects Antiviral Drug Remdesivir as a Covid Treatment
7dWHO Gilead FDA Covid 19
In a review of several trials, the World Health Organization found that Gilead's drug did not improve survival rates for patients nor did it help them recover.
Pivot, Visualize, And Succeed With This Data Analysis Bundle
7dIn the history of personal computing, the date of October 17th, 1979, has a special significance. That's the day the first spreadsheet program for consumers, VisiCalc, went on sale and made the personal computer something every business needed. And while a lot has changed in the intervening decades, one thing hasn't: crunching the numbers, regardless of your business, is a lot easier with a compu
Neuroscience… of the bladder
7dWhen we think of neuroscience, we often think of the brain. […] But so much of neuroscience is concerned with happenings outside the brain itself. For instance, neural signaling controls and coordinates our muscle movements, alerts us when our stomach is empty, produces a physiological response to arousal, and sends a painful alarm when we damage our skin. Neural signaling is also important for
WHO advises against prescribing remdesivir to Covid patients
7dGilead drug has no effect on survival or need for ventilation, says health body
Remdesivir: don't use drug Trump took for Covid-19, WHO says
7dAgency says no evidence the intravenous antiviral works for severe infections Coronavirus – latest updates See all our coronavirus coverage Remdesivir, one of the drugs Donald Trump took when he developed Covid-19, should not be used in hospitals because there is no evidence it works, the World Health Organization has advised. The US president was an enthusiastic proponent of the drug, to the poi
Asteroid-Hunting Telescope Is Being Urgently Taken Down to Avoid 'Catastrophic' Collapse
7dThe gut punches just keep coming.
Coronavirus live news: China has given 1m people Sinopharm vaccine; US CDC warns against Thanksgiving travel
7dCEO of state-owned Sinopharm says there have been 'no adverse effects'; US has recorded 1m cases in past week; Russia and Japan on 'maximum alert' California enacts coronavirus curfew for majority of state's 40m residents One death from Covid every 17 seconds in Europe 'Massive headache': European leaders put off Christmas decisions Brexit trade talks suspended after negotiator's Covid infection
C.D.C. Pleads With Americans to Stay Home on Thanksgiving
7dEven as the White House downplays the coronavirus threat, health officials warned against traditional gatherings with those from outside the immediate household.
The Lancet Microbe: Infectiousness peaks early in COVID-19 patients, emphasising the need to rapidly isolate cases
7dAlthough SARS-CoV-2 genetic material may still be detected in respiratory or stool samples for several weeks, no live virus (that can cause infection) was found in any type of sample collected beyond nine days of symptoms starting and people with SARS-CoV-2 are mostly likely to be highly infectious from symptom onset and the following five days, according to a systematic review and meta-analysis o
Artificial intelligence & satellite technologies reveal detailed map of air pollution across UK
7dA novel method that combines artificial intelligence with remote sensing satellite technologies has produced the most detailed coverage of air pollution in Britain to date.Highlighted by new research led by the London School of Hygiene & Tropical Medicine (LSHTM) and published in Remote Sensing, the methodology provides accurate estimates of concentrations of air pollution across Great Britain.
The Final Pandemic Surge Is Crashing Over America
7dEditor's Note: The Atlantic is making vital coverage of the coronavirus available to all readers. Find the collection here . Updated at 11:51 a.m. ET on November 20, 2020. Understanding the pandemic this week requires grasping two thoughts at once. First, the United States has never been closer to defeating the pandemic. Second, some of the country's most agonizing days still lie ahead. Long term
Publisher Correction: Room-temperature superconductivity in a carbonaceous sulfur hydride
7dNature, Published online: 20 November 2020; doi:10.1038/s41586-020-2955-8
Author Correction: Determination of RNA structural diversity and its role in HIV-1 RNA splicing
7dNature, Published online: 20 November 2020; doi:10.1038/s41586-020-2949-6
Your pee could be the golden ticket to a greener world
7dWe're flushing a lot of valuable nutrients down the drain. (Markus Spiske/) While many of us simply flush and forget about it, our pee has the potential to be a valuable resource. Urine contains the nutrients nitrogen, phosphorus, and potassium—a trio known in agriculture as NPK—in soluble forms that plants can take up, similar to synthetic fertilizers widely used in crop production. As it's curr
New tool to combat terrorism
7dForensic science experts are refining an innovative counter-terrorism technique that checks for environmental DNA in the dust on clothing, baggage, shoes or even a passport.
Putting 'Wonder Woman 1984' on HBO Max Is a Smart Move
7dIt'll be a while before US theaters are back to full capacity. Offering the 'Wonder Woman' sequel on its streaming service is Warner Bros.' best option.
Northern Ireland's executive imposes new Covid-19 curbs
7dNon-essential shops to close for a fortnight from November 27
New tool to combat terrorism
7dForensic science experts are refining an innovative counter-terrorism technique that checks for environmental DNA in the dust on clothing, baggage, shoes or even a passport.
Stem cell transplantation: Undesirable rejection mechanism identified
7dIn the treatment of leukemia, stem cell transplantation subsequent to chemotherapy and radiation can often engender severe adverse inflammatory reactions – especially in the skin or in the gut, since these so-called barrier organs are more frequently affected. Up until now, the reason for this was unclear. A team of researchers has now identified an immune mechanism that is partially responsible f
'Oasis effect' in urban parks could contribute to greenhouse gas emissions
7dFollowing a year of on-site analyses at a Phoenix-area park, hydrologists identified that the park showed what meteorologists call the 'oasis effect,' a microclimate that is cooler than a surrounding dry area due to the evaporation of a water source.
Solving a mystery: How the TB bacterium develops rapid resistance to antibiotics
7dThese slow growing bacteria have long puzzled TB researchers with their fairly rapid resistance to antibiotics. Researchers may have been barking up the wrong tree in exploring genetics, because the answer seems to lie in the epigenetic domain.
Cellular pathway of genetic heart disease similar to neurodegenerative disease
7dResearch on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy.
Missing the radiological forest for the trees
7dEven experienced radiologists, when looking for one abnormality, can completely miss another. The results show that inattentional blindness can befall even experts.
New understanding of mobility paves way for tomorrow's transport systems
7dResearchers have developed a ground-breaking model that provides a completely new understanding of our movement patterns. The model can come to play an important role when designing tomorrow's green modes of transport.
Does air pollution increase women's risk of dementia?
7dOlder women who live in locations with higher levels of air pollution may have more brain shrinkage, the kind seen in Alzheimer's disease, than women who live in locations with lower levels, according to a new study.
The Tragedy of a Ruined Telescope
7dOne of the most powerful telescopes in the world is on the brink of collapse. Arecibo, a giant radio observatory nestled in the lush mountains of Puerto Rico, did some of the dreamiest work in astronomy. But it was forced to stop operations this year after suffering unprecedented damage, and officials now believe that it is beyond repair. Instead of trying to fix it, they're going to tear it down
NASA Admits It Probably Won't Be Able to Land Moon Astronauts by 2024
7dArtemis 202x In a recent report, NASA admitted that landing the first astronauts on the Moon since the Apollo era in 2024 might be a bit of a stretch, as The Guardian reports . The report , released by the agency's inspector general last week, elucidates the budgetary challenges involved in realizing its Artemis program. NASA would need to request "approximately $28 billion between 2021 and 2025,
Mediastinal tuberculoma mimicking malignant cardiac tumor
7dIn a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0587, Yiqian Ding, Wei Li, Yanqiu Liu, Min Ye, Liangping Cheng, Donghong Liu, Hong Lin and Fengjuan Yao from The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China consider mediastinal tuberculoma mimicking malignant cardiac tumors.
Importance of mitochondrial-related genes in dilated cardiomyopathy
7dImportance of Mitochondrial-Related Genes in Dilated Cardiomyopathy Based on Bioinformatics Analysis. In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0588, Yukuan Chen, Xiaohui Wu, Danchun Hu and Wei Wang, from the Shantou University Medical College, Shantou, China and Second Affiliated Hospital of Shantou University Medical College, Sh
In-stent thrombosis after antiplatelet therapy conversion while awaiting coronary bypass
7dIn a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0589, Nathan Burke, Tawanna Charlton, Hussam Hawamdeh, and Ki Park from the University of Florida College of Medicine, Gainesville, Florida, USA consider a case study of in-stent thrombosis after antiplatelet therapy conversion while awaiting coronary bypass.
A case of pediatric heart failure caused by anomalous origin of the left coronary artery from the pulmonary artery
7dIn a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0585, Lei Zhang, Tiewei Lv, Xiaoyan Liu, Chuan Feng, Min Zheng, Jie Tian and Huichao Sun from the Children's Hospital of Chongqing Medical University, Chongqing, China and the Chongqing Key Laboratory of Pediatrics, Chongqing, China consider a case of pediatric heart failure caused by anom
Expand Your Mind as an Adult with Brilliant's Unique Learning Platform
7dWe spend much of our early lives surrounded by math, programming, logic, and other qualitative skills. But once we hit a certain age, that math takes on a certain tone, driven by spreadsheets and emails, instead of joy and creativity. What makes Brilliant, an online learning platform, so fascinating is that it brings the joy and creativity back to learning and honing your qualitative and analytic
How Lil Nas X Obtained an Actual SpaceX Helmet
7dLoaner Helmet Musician Lil Nas X, of " Old Town Road " fame, recently starred in a photoshoot for the magazine Highsnobiety . Lil Nas X was the subject of the cover story of the magazine's new offshoot, HIGHTech , so the photoshoot had an appropriately-futuristic theme inspired by the film "2001: A Space Odyssey." The piece de resistance of the shoot, however, was a genuine SpaceX astronaut helme
Three reasons why COVID-19 can cause silent hypoxia
7dTo crack the mystery of what causes silent hypoxia, a condition when oxygen levels in the body are abnormally low, biomedical engineers used computer modeling to test out three different scenarios that help explain how and why the lungs stop providing oxygen to the bloodstream.
Cesarean section-born children may face higher risk of infection-related hospitalization
7dChildren born via cesarean section may be more likely to be hospitalized for infection during early childhood. A new study suggests that compared to vaginally born children, cesarean-born children may have a higher risk of infection-related hospitalization for up to five years of age.
How the flu virus spreads within cities
7dNew insights into the local transmission of seasonal influenza may be valuable for planning interventions to combat the spread of respiratory diseases within cities, according to a new study.
Breathing problems in teens: COVID-19 or lung injury due to vaping?
7dIn a case series of three teen patients, pediatricians present common manifestations of COVID-19 and lung injury due to vaping (EVALI). As EVALI and COVID-19 share many symptoms, it is critical for health providers to get the vaping history of teenagers with unexplained breathing problems.
Ovarian cancer cells cooperate to metastasize
7dIn a study on human ovarian cancer cells in mice, researchers discovered a transient, cooperative interaction between cell subpopulations that allows otherwise nonmetastatic tumor cells to become aggressive and spread.
Revolutionary CRISPR-based genome editing system treatment destroys cancer cells
7dResearchers have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer. The researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic manipulation. The system, called CRISPR-LNPs, carries a genetic messenger (messenger RNA)
Scientists defy nature to make insta-bling at room temperature
7dAn international team of scientists has defied nature to make diamonds in minutes in a laboratory at room temperature – a process that normally requires billions of years, huge amounts of pressure and super-hot temperatures.
Implantation of an S-ICD in a patient with a DDD pacemaker and congenitally corrected transposition
7dImplantation of an S-ICD in a Patient with a DDD Pacemaker and Congenitally Corrected Transposition of the Great Arteries. In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0597, Yu Zhang, Wen-Long Dai, Can-Can Lin, Qiao-Yuan Li and Cheng-Jun Guo from Beijing Anzhen Hospital, Capital Medical University, Beijing, China consider implantatio
A meta-analysis of major complications between traditional pacemakers and leadless pacemakers
7dA Meta-analysis of Major Complications between Traditional Pacemakers and Leadless Pacemakers. In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0596, Diyu Cui, Yimeng Liao, Jianlin Du and Yunqing Chen from The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China consider major complications between traditional pac
Risk of target organ damage in patients with masked hypertension versus sustained hypertension
7dIn a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.1261, Yue Wu, Guoyue Zhang, Rong Hu and Jianlin Du from The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China consider the risk of target organ damage in patients with masked hypertension versus sustained hypertension.
In a Wild Twist, Asymptomatic Children Can Spread Malaria to Mosquitoes
7dThey can become superspreaders.
Nature Communications looking into paper on mentorship after strong negative reaction
7dA Nature journal has announced that it is conducting a "priority" investigation into a new paper claiming that women in science fare better with male rather than female mentors. The article, "The association between early career informal mentorship in academic collaborations and junior author performance," appeared in Nature Communications on November 17, and was written … Continue reading
Retraction Note: Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction
7dScientific Reports, Published online: 19 November 2020; doi:10.1038/s41598-020-77205-9
A new paper in JEP:General looks at the ability to perceive value in a group of objects. Interesting extension of work on ensemble perception.
7dsubmitted by /u/markmana [link] [comments]
How Animals see the world comparison with Humans. Amazing facts of Animals youtube video by ThoughtCtrl
7dsubmitted by /u/thoughtctrl_official [link] [comments]
College students are less food insecure than non-students
7dCollege students are significantly less likely to be food insecure than non-students in the same age group, according to a new study from the University of Illinois.
China prepares to launch mission to collect moon rocks
7dLong March-5 rocket has been rolled into position for ignition expected this month China is preparing to launch its lunar sample return mission, Chang'e-5 . On Tuesday the 57-metre Long March-5 rocket was rolled into position at the Wenchang spacecraft launch site in south China's Hainan province. This will be the fifth launch of the Long March-5. According to the China National Space Administrat
The promise of the fourth industrial revolution
7dNew technologies can optimize the way people work. When implemented thoughtfully, such innovations can improve overall business processes. Those changes are accepted as part of progress. But when a technology changes how and where people live and their relationships to one another and upends economies, it merits the term "revolution." Because it changes everything. The technology behind the First
Children's Hospital Los Angeles conducts largest pediatric genomic COVID-19 study to date
7dScientists at Children's Hospital Los Angeles analyze the largest group of genetically-sequenced Sars-CoV-2 samples to date. Their findings suggest a potential link between certain mutations and disease severity.
How rotavirus causes severe gastrointestinal disease
7dUsing intercellular calcium waves, rotavirus amplifies its ability to cause disease beyond the cells it directly infects. This is the first virus identified to activate ADP-mediated intercellular calcium waves.
Climate change and 'atmospheric thirst' to increase fire danger and drought in NV and CA
7dClimate change and a "thirsty atmosphere" will bring more extreme wildfire danger and multi-year droughts to Nevada and California by the end of this century, according to new research from the Desert Research Institute (DRI), the Scripps Institution of Oceanography at the University of California, San Diego, and the University of California, Merced.
Analysis of the relations between Spanish civil society organizations and science
7dResearchers at UPF have analysed the relationship between civil society organizations and the Spanish science and technology system. The study has been published in Public Understanding of Science and conducted by Carolina Llorente and Gema Revuelta, at the Science, Communication and Society Studies Centre (CCS-UPF), and Mar Carrió, of the Health Sciences Educational Research Group (GRECS).
Revolutionary CRISPR-based genome editing system treatment destroys cancer cells
7dResearchers have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer. The researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic manipulation. The system, called CRISPR-LNPs, carries a genetic messenger (messenger RNA)
Scientists defy nature to make insta-bling at room temperature
7dAn international team of scientists has defied nature to make diamonds in minutes in a laboratory at room temperature – a process that normally requires billions of years, huge amounts of pressure and super-hot temperatures.
Elephant genetics guide conservation
7dA large-scale study of African elephant genetics in Tanzania reveals the history of elephant populations, how they interact, and what areas may be critical to conserve in order to preserve genetic diversity for species conservation. The study, by researchers at Penn State, appears online in the journal Ecology & Evolution and is the first to explore gene flow—a process vital to maintain necessary
Expanding Cell Growth Capabilities
7dDownload this eBook to learn how to optimize large-scale cell growth using culture shakers, incubators, and bioreactors!
Drug curbs drinking for people with alcohol withdrawal
7dA drug once used to treat high blood pressure can help alcoholics with withdrawal symptoms reduce or eliminate their drinking, researchers report. In a double-blind study, researchers gave the drug prazosin or a placebo to 100 people entering outpatient treatment after receiving an alcohol use disorder diagnosis. All of the patients had experienced varying degrees of withdrawal symptoms prior to
How pigs and manure helped bring down East Germany
7dThe East German communist state's approach to industrial pig farming foreshadowed its demise, a historian argues in a new book. Thomas Fleischman has been obsessed with pigs for the better part of the last decade. Tracing the history of East Germany's birth in the immediate aftermath of World War II to its sudden collapse in 1989, the assistant professor of history at the University of Rochester
Here's How Kids Are Meeting Santa in the Age of the Coronavirus
7dThis year, sitting on Santa's lap could get you a deadly virus for Christmas. But to make sure kids get the same mall Santa tradition that's continued for decades — or at least something resembling it — some companies have adapted to the dangers of the COVID-19 pandemic to find a safe alternative. That means video calls with AI Santas, and for those who would venture out to the mall , lots of pro
Canada govt seeks carbon neutrality by 2050
7dThe government of Canadian Prime Minister Justin Trudeau on Thursday submitted draft legislation that it said would allow the country to be carbon neutral by 2050, but his opponents dismissed the initiative as "smoke and mirrors."
Astronaut: SpaceX Dragon beats shuttle, Soyuz for launching
7dThe most experienced astronaut on SpaceX's newly launched crew said Thursday that riding a Dragon capsule to orbit is like being inside the actual mythical beast, and a lot more fun than NASA's shuttles or Russian flights.
Increasing diversity and community participation in environmental engineering
7dBlack, Hispanic, and Native American students and faculty are largely underrepresented in environmental engineering programs in the United States. A pathway for increasing diversity and community participation in the environmental engineering discipline is proposed in the peer-reviewed journal Environmental Engineering Science.
Elephant genetics guide conservation
7dA large-scale study of African elephant genetics in Tanzania reveals the history of elephant populations, how they interact, and what areas may be critical to conserve in order to preserve genetic diversity for species conservation. The study, by researchers at Penn State, appears online in the journal Ecology & Evolution and is the first to explore gene flow—a process vital to maintain necessary
Researchers identify features that could make someone a virus super-spreader
7dNew research from the University of Central Florida has identified physiological features that could make people super-spreaders of viruses such as COVID-19.
Researchers invent novel vertical-cavity surface-emitting laser
7dResearchers at the George Washington University have developed a new design of vertical-cavity surface-emitting laser (VCSEL) that demonstrates record-fast temporal bandwidth. This was possible by combining multiple transverse coupled cavities, which enhances optical feedback of the laser. VCSELs have emerged as a vital approach for realizing energy-efficient and high-speed optical interconnects i
Predicting forces between oddly shaped nanoparticles
7dMaterials scientists at Duke University have devised a simplified method for calculating the attractive forces that cause nanoparticles to self-assemble into larger structures.
Students discover hidden 15th-century text on medieval manuscripts
7dRochester Institute of Technology students discovered lost text on 15th-century manuscript leaves using an imaging system they developed as freshmen. By using ultraviolet-fluorescence imaging, the students revealed that a manuscript leaf held in RIT's Cary Graphic Arts Collection was actually a palimpsest, a manuscript on parchment with multiple layers of writing.
'Strange rays' crowdsourced on social media shed light on black hole illumination
7dSparked by an image uploaded to Twitter, new research indicates that the light produced by black hole accretion may be bright enough to reflect off of dust, illuminating the host galaxy, and creating light and dark rays similar to the effect of crepuscular rays on Earth. The research is published in The Astrophysical Journal Letters.
NSF plans to decommission Arecibo Observatory's 305m telescope due to safety concerns
7dFollowing a review of engineering assessments that found damage to the Arecibo Observatory cannot be stabilized without risk to construction workers and staff at the facility, the U.S. National Science Foundation will begin plans to decommission the 305-meter telescope, which for 57 years has served as a world-class resource for radio astronomy, planetary, solar system and geospace research.
Vibrations of coronavirus proteins may play a role in infection
7dWhen someone struggles to open a lock with a key that doesn't quite seem to work, sometimes jiggling the key a bit will help. Now, new research from MIT suggests that coronaviruses, including the one that causes COVID-19, may use a similar method to trick cells into letting the viruses inside. The findings could be useful for determining how dangerous different strains or mutations of coronaviruse
The CDC says not to travel on Thanksgiving
7dThe plane isn't the only dangerous part of the equation. (Unsplash/) Follow all of PopSci's COVID-19 coverage here , including the truth about herd immunity , advice for pregnant women , and a tutorial on making your own mask . COVID-19 is on the rise across the United States . This week's new cases have averaged at 162,816 per day, which represents a 77 percent increase from two weeks ago. On Th
Hidden 15th-century text on medieval manuscripts
7dStudents have discovered lost text on 15th-century manuscript leaves using an imaging system they developed as freshmen. By using ultraviolet-fluorescence imaging, the students revealed that a manuscript leaf held in RIT's Cary Graphic Arts Collection was actually a palimpsest, a manuscript on parchment with multiple layers of writing.
Showing robots how to drive a car…in just a few easy lessons
7dResearchers have designed a system that lets robots autonomously learn complicated tasks from a very small number of demonstrations — even imperfect ones. While current state-of-art methods need at least 100 demonstrations to nail a specific task, this new method allows robots to learn from only a handful of demonstrations.
Elephant genetics guide conservation
7dA large-scale study of African elephant genetics in Tanzania reveals the history of elephant populations, how they interact, and what areas may be critical to conserve in order to preserve genetic diversity of the species.
Novel magnetic spray transforms objects into millirobots for biomedical applications
7dAn easy way to make millirobots by coating objects with a glue-like magnetic spray has been developed. Driven by the magnetic field, the coated objects can crawl, walk, or roll on different surfaces. As the magnetic coating is biocompatible and can be disintegrated into powders when needed, this technology demonstrates the potential for biomedical applications, including catheter navigation and dr
Study finds matriarchal societies are good for women's health
7dAn isolated ethnic group in China maintains a matriarchal society, much to the benefit of their health. The Mosuo women were not only healthier than women living under patriarchy, but were healthier than the men too. The findings support the idea that having a degree of autonomy and resource control is good for your health Every debate about what is innate to humans and what is learned from socie
Vibrations of coronavirus proteins may play a role in infection
7dWhen someone struggles to open a lock with a key that doesn't quite seem to work, sometimes jiggling the key a bit will help. Now, new research from MIT suggests that coronaviruses, including the one that causes COVID-19, may use a similar method to trick cells into letting the viruses inside. The findings could be useful for determining how dangerous different strains or mutations of coronaviruse
The secret social lives of giant poisonous rats
7dThe African crested rat (Lophiomys imhausi) is hardly the continent's most fearsome-looking creature—the rabbit-sized rodent resembles a gray puffball crossed with a skunk—yet its fur is packed with a poison so lethal it can fell an elephant and just a few milligrams can kill a human. In a Journal of Mammology paper published today, the University of Utah, Smithsonian Conservation Biology Institut
Green hydrogen: Buoyancy-driven convection in the electrolyte
7dHydrogen produced by using solar energy could contribute to a climate neutral energy system of the future. But there are hurdles on the way from laboratory scale to large-scale implementation. A team at HZB has now presented a method to visualize convection in the electrolyte and to reliably simulate it in advance with a multiphysics model. The results can support the design and scaling up of this
Researchers have succeeded in directly observing the formation and interaction of highly ionized krypton plasma
7dThe last decade has been marked by a series of remarkable discoveries identifying how the universe is composed. It is understood that the mysterious substance dark matter makes up 85 % of the matter in the universe. Observable matter in the universe consists of ionized particles. Thus, a profound understanding of ionized matter and its interaction with light, could lead to a deeper understanding o
Sky survey reveals newborn jets in distant galaxies
7dAstronomers using data from the ongoing VLA Sky Survey (VLASS) have found a number of distant galaxies with supermassive black holes at their cores that have launched powerful, radio-emitting jets of material within the past two decades or so. The scientists compared data from VLASS with data from an earlier survey that also used the National Science Foundation's Karl G. Jansky Very Large Array (V
Program successful in increasing private donations to public universities, study shows
7dA new study suggests that the Texas Research Incentive Program (TRIP) has succeeded in boosting the amount of private donations to public universities, indicating that policymakers can effectively leverage public investment to spur private donations.
The secret social lives of giant poisonous rats
7dThe African crested rat (Lophiomys imhausi) is hardly the continent's most fearsome-looking creature—the rabbit-sized rodent resembles a gray puffball crossed with a skunk—yet its fur is packed with a poison so lethal it can fell an elephant and just a few milligrams can kill a human. In a Journal of Mammology paper published today, the University of Utah, Smithsonian Conservation Biology Institut
Researchers present insights in the search for new antibiotics
7dA collaborative research team from the University of Oklahoma, the Memorial Sloan Kettering Cancer Center and Merck & Co. published an opinion article in the journal, Nature Chemical Biology, that addresses the gap in the discovery of new antibiotics.
Plastic film used to protect foods and surfaces inactivates novel coronavirus
7dTransparent stretchable PVC film for use in packaging meat, fruit, cold cuts, and other foods, and to protect surfaces, can inactivate the novel coronavirus.
Researchers present insights in the search for new antibiotics
7dA collaborative research team from the University of Oklahoma, the Memorial Sloan Kettering Cancer Center and Merck & Co. published an opinion article in the journal, Nature Chemical Biology, that addresses the gap in the discovery of new antibiotics.
Tel Aviv University study finds hyperbaric oxygen treatments reverse aging process
7dA new study from Tel Aviv University (TAU) and the Shamir Medical Center in Israel indicates that hyperbaric oxygen treatments (HBOT) in healthy aging adults can stop the aging of blood cells and reverse the aging process. In the biological sense, the adults' blood cells actually grow younger as the treatments progress.
Increasing diversity and community participation in environmental engineering
7dBlack, Hispanic, and Native American students and faculty are largely underrepresented in environmental engineering programs in the ) States. A pathway for increasing diversity and community participation in the environmental engineering discipline
UCF researchers identify features that could make someone a virus super-spreader
7dIn a study in Physics of Fluids, UCF researchers used computer-generated models to numerically simulate sneezes in different types of people and determine associations between people's physiological features and how far their sneeze droplets travel and linger in the air. They found that people's features, like a stopped-up nose or a full set of teeth, could increase their potential to spread virus
Three reasons why COVID-19 can cause silent hypoxia
7dTo crack the mystery of what causes silent hypoxia, a condition when oxygen levels in the body are abnormally low, BU biomedical engineers used computer modeling to test out three different scenarios that help explain how and why the lungs stop providing oxygen to the bloodstream.
Breaking the power and speed limit of lasers
7dResearchers at the George Washington University have developed a new design of vertical-cavity surface-emitting laser (VCSEL) that demonstrates record-fast temporal bandwidth.
Long-acting antipsychotic therapy plus cognitive training show promise for schizophrenia
7dUCLA scientists and colleagues found the use of long-acting antipsychotic medication combined with the use of cognitive training in group settings led to improved cognition and increased productivity.
Italian Lambo Police Car Covers 300 Miles in 2 Hours to Deliver Kidney
7dAn intrepid Italian police officer got a cool task, Jalopnik reports : cover 300 miles in just two hours, while driving an official police-issued Lamborghini Huracán , to deliver a donor kidney. That's an average speed of 143 mph, cutting a six hour journey from Rome to Padua to a mere third of its usual time. Grazie alla nostra @Lamborghini Huracan abbiamo trasportato in tempo il rene di un dona
Protect Yourself with Two Years of NordVPN And Password Protection
7dWhile the websites and social media platforms and apps we use constantly reassure us that our data's safe with them, there seem to be relentless data breaches and questionable uses of what should be private data. As we become more mobile, working remotely, and staying in touch via Zoom and other tools, privacy and protection will only become more important. Fortunately, Nord's now making it easy
Very hungry and angry, caterpillars head-butt to get what they want
7dWhen food is scarce, monarch butterfly caterpillars go from docile to domineering. The results look something like a combination of boxing and 'bumper' cars. The less food, the more likely caterpillars were to try to head-butt each other out of the way to get their fill, lunging and knocking aside other caterpillars to ensure their own survival. And, they are most aggressive right before the final
Maraxilibat reduces debilitating itching in children with Alagille syndrome
7dOn behalf of Childhood Liver Disease Research Network (ChiLDReN), Texas Children's Hospital and Baylor College of Medicine researchers report that prolonged treatment with Maraxilibat resulted in clinically meaningful improvements in debilitating itching (pruritus) and related quality of life outcomes in children with Alagille syndrome. The novel pharmacological approach addresses a major unfulfil
Elephant genetics guide conservation
7dA large-scale study of African elephant genetics in Tanzania reveals the history of elephant populations, how they interact, and what areas may be critical to conserve in order to preserve genetic diversity of the species.
Engineered immune cells elicit broad response to HIV in mice, offering hope for vaccine
7dUnlike so many other deadly viruses, HIV still lacks a vaccine. The virus has proven especially tricky to prevent with conventional antibodies, in part because it evolves so rapidly in the body. A solution would require coaxing the body into producing a special type of antibody that can act broadly to defeat multiple strains of the virus at once. Scientists at Scripps Research moved closer to atta
Oncotarget: IGF2 expression in breast cancer tumors and in breast cancer cells
7d"The Oncotarget authors propose that methylation of DVDMR represents a novel epigenetic biomarker that determines the levels of IGF2 protein expression in breast cancer."
Showing robots how to drive a car…in just a few easy lessons
7dUSC researchers have designed a system that lets robots autonomously learn complicated tasks from a very small number of demonstrations–even imperfect ones.While current state-of-art methods need at least 100 demonstrations to nail a specific task, this new method allows robots to learn from only a handful of demonstrations.
Predicting forces between oddly shaped nanoparticles
7dMaterials scientists at Duke University have devised a simplified method for calculating the forces that cause nanoparticles to self-assemble. With this new model and graphical user interface, researchers will be able to make previously impossible predictions about how nanoparticles with a wide variety of shapes will interact with one another. The new method offers opportunities for rationally des
RIT students discover hidden 15th-century text on medieval manuscripts
7dRochester Institute of Technology students discovered lost text on 15th-century manuscript leaves using an imaging system they developed as freshmen. By using ultraviolet-fluorescence imaging, the students revealed that a manuscript leaf held in RIT's Cary Graphic Arts Collection was actually a palimpsest, a manuscript on parchment with multiple layers of writing.
What Will Happen to the Far-Right After Trump?
7dAs president-elect Biden's inauguration approaches, experts are keeping an eye on extremist groups.
Could kelp help relieve ocean acidification?
7dA new analysis of California's Monterey Bay evaluates kelp's potential to reduce ocean acidification, the harmful fallout from climate change on marine ecosystems and the food they produce for human populations.
Mystery solved: 'New Kind of Electrons'
7dWhy do certain materials emit electrons with a very specific energy? This has been a mystery for decades – scientists have now found an answer.
Study identifies reasons for soaring nuclear plant cost overruns in the US
7dResearchers have analyzed the causes of many cost overruns on new nuclear power plants in the US, which have soared in the past 50 years. The findings may help designers of new plants build in resilience to prevent such added costs.
Versatile building blocks make structures with surprising mechanical properties
7dResearchers have created tiny building blocks that exhibit unique mechanical properties, such as the ability to produce a twisting motion when squeezed. These subunits could potentially be assembled by robots into a nearly limitless variety of objects with built-in functionality, including vehicles, large industrial parts, or specialized robots that can be repeatedly reassembled in different forms
Lethal brain infections in mice thwarted by decoy molecule
7dResearchers have identified a molecule that protects mice from brain infections caused by Venezuelan equine encephalitis virus (VEEV), a mosquito-borne virus notorious for causing fast-spreading, deadly outbreaks in Mexico, Central America and northern South America.
A genetic link to molecular events that precede symptoms in Alzheimer's disease
7dResearchers find a key mutation causing abnormal transport of BACE1, the enzyme responsible for processing the Alzheimer's disease-linked amyloid protein. Identification of this mutation, which is more common among African Americans with Alzheimer's, may allow early intervention.
Leftover Milk Could be the Key Ingredient for Carbon Capture Tech
7dSpilt Milk One elusive white whale in the fight against climate change has been carbon capture: tech that could scrub carbon dioxide out of the atmosphere, but hasn't yet been developed at scale . The trick is finding the right material that can bind to carbon atoms released into the air. Now, scientists from Clarkson University say they've found the best one yet — waste milk. The unpleasant-soun
H.I.V. Death Rates Fell by Half 2010-2018, C.D.C. Says
7dFrom 2010 to 2018, significantly fewer people died of H.I.V.-related causes, although survival rates for women and people of color did not improve as much.
No Flying Cars Yet, But How About a $300 Toaster With a Touch Screen?
7dToast. It's typically prepared by carefully burning both sides of a piece of fungus-infused grain paste that's been previously cooked until it formed a solid mass. Once this intermediate stage, known as "bread" has been produced, a second piece of equipment called a "toaster" is deployed. This second appliance is responsible for transforming bread into its scorched, dehydrated form. Dedicated har
Can eating mangoes reduce women's facial wrinkles?
7dA new study from researchers at the University of California, Davis, finds eating Ataulfo mangoes, also known as honey or Champagne mangoes, may reduce facial wrinkles in older women with fairer skin. But too much mango may increase wrinkles.
Information Overload Helps Fake News Spread, and Social Media Knows It
7dUnderstanding how algorithm manipulators exploit our cognitive vulnerabilities empowers us to fight back — Read more on ScientificAmerican.com
Plastics an 'unfolding disaster' for US marine life
7dFor the first time, advocates have tracked how animals in US waters are harmed by plastic pollution.
Could kelp help relieve ocean acidification?
7dA new analysis of California's Monterey Bay evaluates kelp's potential to reduce ocean acidification, the harmful fallout from climate change on marine ecosystems and the food they produce for human populations.
A neural network learns when it should not be trusted
7dMIT researchers have developed a way for deep learning neural networks to rapidly estimate confidence levels in their output. The advance could enhance safety and efficiency in AI-assisted decision making, with applications ranging from medical diagnosis to autonomous driving.
DeepER tool uses deep learning to better allocate emergency services
7dResearchers at Binghamton University, State University of New York has used deep-learning techniques to analyze statistics on emergencies in NYC to suggest improved public safety through re-allocation of resources.
Chemicals banned for decades still show up in terns
7dChemicals not manufactured in the US for years or even decades still turn up in the bodies of migratory terns in the Great Lakes region, a new study finds. The research focused on three types of compounds: polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), and the breakdown products, called metabolites, of dichlorodiphenyltrichloroethane (DDT). "These chemicals are still th
Newborn jets in distant galaxies
7dComparing data from VLA sky surveys made some two decades apart revealed that the black hole-powered 'engines' at the cores of some distant galaxies have launched new, superfast jets of material during the interval between the surveys.
Study finds low risk of pregnancy complications from COVID-19
7dPregnant women who test positive for COVID-19 and their newborn babies have a low risk of developing severe symptoms, according to a new study.
Vibrations of coronavirus proteins may play a role in infection
7dNew research finds vibrations of the protein spikes on coronaviruses, including SARS-CoV-2, play a crucial part in allowing the virus to penetrate human cells. The findings could help determine how dangerous different strains or mutations of coronaviruses may be, and might point to a new approach to developing treatments.
Loneliness in youth could impact mental health over the long term
7dA new review reports on the available evidence about children and young people specifically, stating that loneliness is associated with mental health problems, including depression and anxiety-potentially affecting them years later.
Early details of brain damage in COVID-19 patients
7dLooking at six patients using a specialized magnetic resonance technique, researchers found that COVID-19 patients with neurological symptoms show some of the same metabolic disturbances in the brain as other patients who have suffered oxygen deprivation from other causes, but there are also notable differences.
US emissions plummeted this year—for all the wrong reasons
7dThe good news: US greenhouse-gas emissions are on track to fall 9% this year, marking the lowest levels of climate pollution in at least three decades, according to the research group BloombergNEF . The bad news: The dramatic decline is almost entirely attributable to the pandemic-driven economic downturn, not to any fundamental and lasting shifts in our policies, behaviors, and practices. BNEF e
Learn The Future of Finance with the Ultimate FinTech Bundle
7dThe future of finance is digital. You know this by now. While cryptocurrencies and blockchain draw plenty of attention, there's even more going on inside the finance industry rapidly changing how we invest, spend, and transfer money around the world — without even realizing it. The Ultimate FinTech & Blockchain Bootcamp Bundle, just $39.99, a 97% discount , will get you caught up to the cutting e
Vibrations of coronavirus proteins may play a role in infection
7dNew research finds vibrations of the protein spikes on coronaviruses, including SARS-CoV-2, play a crucial part in allowing the virus to penetrate human cells. The findings could help determine how dangerous different strains or mutations of coronaviruses may be, and might point to a new approach to developing treatments.
Ice Drownings Expected to Rise as Winters Warm
7dRising temperatures could put cold-climate pastimes like skating on thin ice—literally — Read more on ScientificAmerican.com
Scientists discover roles for a cellular motor in cancer
7dUtah scientists have discovered new functions of a key cellular machine that regulates gene packaging and is mutated in 20% of human cancers. The study was published in print today in the journal Molecular Cell.
CLCN6 identified as disease gene for a severe form of lysosomal neurodegenerative disease
7dA mutation in the CLCN6 gene is associated with a novel, particularly severe neurodegenerative disorder. Scientists from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and the Max Delbrück Center für Molekulare Medizin (MDC), together with an international team of researchers, have now analyzed the effect of a point mutation that was found in three unrelated affected children.
Two liquids of water exist
7dUsing x-ray lasers, researchers at Stockholm University have been able to follow the transformation between two distinct different liquid states of water, both being made of H2O molecules. At around -63 Centigrade the two liquids exist at different pressure regimes with a density difference of 20%. By rapidly varying the pressure before the sample could freeze, it was possible to observe one liqui
Researchers prove water has multiple liquid states
7dWhen water reaches approximately -63 degrees centigrade it can separate into two liquid states, with one liquid being 20% more dense than the other. This is a fundamental finding that explains many of the anomalous properties of water at low temperatures. The finding has potential implications in low-temperature chemical and biochemical processes in aqueous environments.
Researchers recommend more transparency for gene-edited crops
7dTo gain trust, NC State researchers recommend a wide-ranging coalition that would provide more transparency on the presence and use of gene editing in food supplies.
Cesarean-born babies at increased risk of infection-related hospitalisation in childhood
7dCesarean-born babies are at increased risk during early childhood of being hospitalised due to an infection, according to a new study of over seven million births from four countries.
'Domestication' increases mosquito's zika virus susceptibility
7dThe Aedes aegypti aegypti subspecies of mosquito, which has become a "domestic" pest worldwide, can acquire and transmit Zika virus more easily than its African forerunner.
Building a better electronic touch
7dTwo new studies introduce materials that improve the capabilities of electronic 'touch,' boosting the multimodality of artificial skin so that it more resembles the capabilities of human skin.
Marine bacterium yields promising new antifungal
7dA molecule extracted from a bacterium living inside a sea squirt acts as a potent antifungal, even against multidrug-resistant fungal pathogens such as Candida auris, according to Fan Zhang and colleagues.
Climate warming increases infectious disease risk in cooler-climate species
7dAccelerated climate warming may increase the risk for infectious disease outbreaks in many species adapted to mild and cooler climates, whereas species from warmer climates could experience reductions in disease risk, reports a new study.
Greater mosquito susceptibility to Zika virus fueled the epidemic
7dBy experimentally comparing wild populations of Ae. aegyptithe researchers discovered that the invasive subspecies is very effective at transmitting the Zika virus not only because it has more frequent contacts with humans for blood meals, but also as a result of its greater susceptibility to the virus relative to the African subspecies.
A pressure sensor at your fingertips
7dResearchers have developed an ultrathin pressure sensor that can be attached directly to the skin. It can measure how fingers interact with objects to produce useful data for medical and technological applications. The sensor has minimal effect on the users' sensitivity and ability to grip objects, and it is resistant to disruption from rubbing. The team also hopes their sensor can be used for the
Molecular telegraphy: precisely sending and receiving single molecules
7dResearchers of the University of Graz, Austria, managed to send single molecules to a distant location and receive them from there. The study appears as the cover story in the current issue of the magazine Science.
New effective and safe antifungal isolated from sea squirt microbiome
7dBy combing the ocean for antimicrobials, scientists at the University of Wisconsin-Madison have discovered a new antifungal compound that efficiently targets multi-drug-resistant strains of deadly fungi without toxic side effects in mice.
Cesarean section-born children may face higher risk of infection-related hospitalization
7dChildren born via cesarean section may be more likely to be hospitalized for infection during early childhood. A study published in PLOS Medicine by Jessica Miller at the Murdoch Children's Research Institute, Australia and colleagues suggests that compared to vaginally-born children, cesarean-born children may have a higher risk of infection-related hospitalization for up to five years of age.
How the flu virus spreads within cities
7dNew insights into the local transmission of seasonal influenza may be valuable for planning interventions to combat the spread of respiratory diseases within cities, according to a study published November 19, 2020 in the open-access journal PLOS Pathogens by Nicola Müller and Tanja Stadler of ETH Zürich, and colleagues.
Dementia risk may be higher for lesbian, gay, bi adults
7dLesbian, gay and bisexual—or LGB—people are more vulnerable to dementia, according to new research. "Our study speaks to the unaddressed questions about whether members the LGB community are more likely to develop cognitive impairment at older ages and, if so, what factors contribute to their poorer cognitive health, " says Ning Hsieh, an assistant professor of sociology at Michigan State Univers
Experts fear Thanksgiving COVID spikes—Can you have your turkey and stay healthy too ?
7dHoliday travel and family gatherings will bolster America's already growing number of coronavirus cases, experts warn. The CDC recommends families celebrating with people outside their quarantine households follow extra precautions. For families staying physically distant, there remain many ways to connect with each other this Thanksgiving. Like any holiday, Thanksgiving has always had challenges
CT scans and X-rays may up testicular cancer risk
7dEarly and repeated exposures to diagnostic imaging, such as X-rays and CT scans, may increase the risk of testicular cancer, according to a new study. "The steady rise in testicular germ cell tumor (TGCT) cases over the past three or four decades suggests there is an environmental exposure risk at play, but no definitive risk factor has ever been identified," says Katherine L. Nathanson, deputy d
Elon Musk: First Mars City Will Start With Glass Domes
7dSpaceX CEO Elon Musk has some ambitious plans to turn humanity into an multiplanetary species. With the aid of a fleet of Starship spacecraft, the intrepid billionaire wants to establish a permanent foothold on Mars, one million people strong, by 2050 . Now, Musk is publicly fleshing out his vision further. "Life in glass domes at first," Musk wrote in a Thursday tweet, responding to a question a
Famed Arecibo Radio Telescope to be Decommissioned After Cable Failures
7dEngineers have concluded Arecibo Observatory cannot be safely repaired after the failure of two cables.
Fire and biodiversity in the Anthropocene
7dFire has been a source of global biodiversity for millions of years. However, interactions with anthropogenic drivers such as climate change, land use, and invasive species are changing the nature of fire activity and its impacts. We review how such changes are threatening species with extinction and transforming terrestrial ecosystems. Conservation of Earth's biological diversity will be achieve
Response to Comment on "Ancient origins of allosteric activation in a Ser-Thr kinase"
7dPark et al . question one out of seven findings from Hadzipasic et al .: whether TPX2 allosterically regulates the oldest Aurora. We had already addressed the two concerns raised—sparse sequence sampling and not forcing the gene to the species tree—before publication. Moreover, we believe their ancestral sequence reconstruction would be consistent with a nonallosteric common ancestor, and we show
An extremely metal-deficient globular cluster in the Andromeda Galaxy
7dGlobular clusters (GCs) are dense, gravitationally bound systems of thousands to millions of stars. They are preferentially associated with the oldest components of galaxies, so measurements of their composition can constrain the build-up of chemical elements in galaxies during the early Universe. We report a massive GC in the Andromeda Galaxy (M31), RBC EXT8, that is extremely depleted in heavy
A marine microbiome antifungal targets urgent-threat drug-resistant fungi
7dNew antifungal drugs are urgently needed to address the emergence and transcontinental spread of fungal infectious diseases, such as pandrug-resistant Candida auris. Leveraging the microbiomes of marine animals and cutting-edge metabolomics and genomic tools, we identified encouraging lead antifungal molecules with in vivo efficacy. The most promising lead, turbinmicin, displays potent in vitro a
Experimental observation of the liquid-liquid transition in bulk supercooled water under pressure
7dWe prepared bulk samples of supercooled liquid water under pressure by isochoric heating of high-density amorphous ice to temperatures of 205 ± 10 kelvin, using an infrared femtosecond laser. Because the sample density is preserved during the ultrafast heating, we could estimate an initial internal pressure of 2.5 to 3.5 kilobar in the high-density liquid phase. After heating, the sample expanded
Oceanic plateau of the Hawaiian mantle plume head subducted to the uppermost lower mantle
7dThe Hawaiian-Emperor seamount chain that includes the Hawaiian volcanoes was created by the Hawaiian mantle plume. Although the mantle plume hypothesis predicts an oceanic plateau produced by massive decompression melting during the initiation stage of the Hawaiian hot spot, the fate of this plateau is unclear. We discovered a megameter-scale portion of thickened oceanic crust in the uppermost lo
Tissue topography steers migrating Drosophila border cells
7dMoving cells can sense and respond to physical features of the microenvironment; however, in vivo, the significance of tissue topography is mostly unknown. Here, we used Drosophila border cells, an established model for in vivo cell migration, to study how chemical and physical information influences path selection. Although chemical cues were thought to be sufficient, live imaging, genetics, mod
Enhanced Zika virus susceptibility of globally invasive Aedes aegypti populations
7dThe drivers and patterns of zoonotic virus emergence in the human population are poorly understood. The mosquito Aedes aegypti is a major arbovirus vector native to Africa that invaded most of the world's tropical belt over the past four centuries, after the evolution of a "domestic" form that specialized in biting humans and breeding in water storage containers. Here, we show that human speciali
Divergent impacts of warming weather on wildlife disease risk across climates
7dDisease outbreaks among wildlife have surged in recent decades alongside climate change, although it remains unclear how climate change alters disease dynamics across different geographic regions. We amassed a global, spatiotemporal dataset describing parasite prevalence across 7346 wildlife populations and 2021 host-parasite combinations, compiling local weather and climate records at each locat
Rotavirus induces intercellular calcium waves through ADP signaling
7dRotavirus causes severe diarrheal disease in children by broadly dysregulating intestinal homeostasis. However, the underlying mechanism(s) of rotavirus-induced dysregulation remains unclear. We found that rotavirus-infected cells produce paracrine signals that manifested as intercellular calcium waves (ICWs), observed in cell lines and human intestinal enteroids. Rotavirus ICWs were caused by th
Architecture of the photosynthetic complex from a green sulfur bacterium
7dThe photosynthetic apparatus of green sulfur bacteria (GSB) contains a peripheral antenna chlorosome, light-harvesting Fenna-Matthews-Olson proteins (FMO), and a reaction center (GsbRC). We used cryo–electron microscopy to determine a 2.7-angstrom structure of the FMO-GsbRC supercomplex from Chlorobaculum tepidum . The GsbRC binds considerably fewer (bacterio)chlorophylls [(B)Chls] than other kno
Comment on "Ancient origins of allosteric activation in a Ser-Thr kinase"
7dHadzipasic et al . (Reports, 21 February 2020, p. 912) used ancestral sequence reconstruction to identify historical sequence substitutions that putatively caused Aurora kinases to evolve allosteric regulation. We show that their results arise from using an implausible phylogeny and sparse sequence sampling. Addressing either problem reverses their inferences: Allostery and the amino acids that c
Gene regulatory networks controlling vertebrate retinal regeneration
7dInjury induces retinal Müller glia of certain cold-blooded vertebrates, but not those of mammals, to regenerate neurons. To identify gene regulatory networks that reprogram Müller glia into progenitor cells, we profiled changes in gene expression and chromatin accessibility in Müller glia from zebrafish, chick, and mice in response to different stimuli. We identified evolutionarily conserved a
Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau
7dNeurodegeneration in Alzheimer's disease (AD) is closely associated with the accumulation of pathologic tau aggregates in the form of neurofibrillary tangles. We found that a p.Asp395Gly mutation in VCP (valosin-containing protein) was associated with dementia characterized neuropathologically by neuronal vacuoles and neurofibrillary tangles. Moreover, VCP appeared to exhibit tau disaggregase act
A human tissue screen identifies a regulator of ER secretion as a brain-size determinant
7dLoss-of-function (LOF) screens provide a powerful approach to identify regulators in biological processes. Pioneered in laboratory animals, LOF screens of human genes are currently restricted to two-dimensional cell cultures, which hinders the testing of gene functions requiring tissue context. Here, we present CRISPR–lineage tracing at cellular resolution in heterogeneous tissue (CRISPR-LICHT),
Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE
7dMast cells (MCs) are central effector cells in allergic reactions that are often mediated by immunoglobulin E (IgE). Allergies commonly start at an early age, and both MCs and IgE are detectable in fetuses. However, the origin of fetal IgE and whether fetal MCs can degranulate in response to IgE-dependent activation are presently unknown. Here, we show that human and mouse fetal MCs phenotypicall
Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
7dEfficient therapeutic options are needed to control the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has caused more than 922,000 fatalities as of 13 September 2020. We report the isolation and characterization of two ultrapotent SARS-CoV-2 human neutralizing antibodies (S2E12 and S2M11) that protect hamsters against SARS-CoV-2 challenge. Cryo–electron microscopy st
Control of long-distance motion of single molecules on a surface
7dSpatial control over molecular movement is typically limited because motion at the atomic scale follows stochastic processes. We used scanning tunneling microscopy to bring single molecules into a stable orientation of high translational mobility where they moved along precisely defined tracks. Single dibromoterfluorene molecules moved over large distances of 150 nanometers with extremely high sp
Artificial multimodal receptors based on ion relaxation dynamics
7dHuman skin has different types of tactile receptors that can distinguish various mechanical stimuli from temperature. We present a deformable artificial multimodal ionic receptor that can differentiate thermal and mechanical information without signal interference. Two variables are derived from the analysis of the ion relaxation dynamics: the charge relaxation time as a strain-insensitive intrin
Nanomesh pressure sensor for monitoring finger manipulation without sensory interference
7dMonitoring of finger manipulation without disturbing the inherent functionalities is critical to understand the sense of natural touch. However, worn or attached sensors affect the natural feeling of the skin. We developed nanomesh pressure sensors that can monitor finger pressure without detectable effects on human sensation. The effect of the sensor on human sensation was quantitatively investi
Fires can kindle biodiversity, sparking new approaches to conservation
7dPreserving natural fires and managing out-of-control blazes helps ecosystems
New genetic tools will deliver improved farmed fish, oysters, and shrimp. Here's what to expect
7dCompanies poised to see big gains from high-tech breeding, but questions remain about gene editing and engineering
Science retracts paper co-authored by high-profile scientist and former Dutch minister
7dScience has retracted a 13-year-old paper, five years after data sleuth Elisabeth Bik first raised questions about issues with the images in the article. The paper, "Secondary siRNAs result from unprimed RNA synthesis and form a distinct class," appeared in 2007 and was written by a group of researchers in the Netherlands and Switzerland. The … Continue reading
VLA sky survey reveals newborn jets in distant galaxies
7dComparing data from VLA sky surveys made some two decades apart revealed that the black hole-powered 'engines' at the cores of some distant galaxies have launched new, superfast jets of material during the interval between the surveys.
Study: Texas program successful in increasing private donations to public universities
7dA new study suggests that the Texas Research Incentive Program (TRIP) has succeeded in boosting the amount of private donations to public universities, indicating that policymakers can effectively leverage public investment to spur private donations.
The secret social lives of giant poisonous rats
7dThe African crested rat is the only mammal known to sequester plant toxins for chemical defense. A new study confirmed that the rabbit-sized rodent licks poison from the bark of Acokanthera schimperi, known as the poison arrow tree, into specialized fur. The researchers also discovered an unexpected social life–the rats appear to be monogamous and may even form small family units with their offsp
Legendary Arecibo Telescope Will Close Forever, and Scientists Are Reeling
7dArecibo Puerto Rico
A new satellite image reveals the damage that shut down the facility, ending an era in astronomical observation — Read more on ScientificAmerican.com
New effective and safe antifungal isolated from sea squirt microbiome
7dBy combing the ocean for antimicrobials, scientists at the University of Wisconsin-Madison have discovered a new antifungal compound that efficiently targets multi-drug-resistant strains of deadly fungi without toxic side effects in mice.
Mosquitos in Asia and the Americas More Susceptible to Zika Virus
7dA study explains how Zika was present among mosquitoes in Africa for decades without causing the harm to human health seen outside the continent in recent years.
An imperceptible thin-film sensor to record movement and the sense of touch
7dResearchers have developed an ultrathin pressure sensor that can be attached directly to the skin and measure how fingers interact with objects to produce useful data for medical and technological applications. The sensor has minimal effect on the users' sensitivity and ability to grip objects, and it is resistant to disruption from rubbing. The team also hopes their sensor can be used for the nov
Researchers prove water has multiple liquid states
7dWater is a ubiquitous liquid with many highly unique properties. The way it responds to changes in pressure and temperature can be completely different from other liquids, and these properties are essential to many practical applications and particularly to life as we know it. What causes these anomalies has long been a source of scientific exploration, but now, an international team of researcher
New effective and safe antifungal isolated from sea squirt microbiome
7dBy combing the ocean for antimicrobials, scientists at the University of Wisconsin-Madison have discovered a new antifungal compound that efficiently targets multi-drug-resistant strains of deadly fungi without toxic side effects in mice.
Researchers recommend more transparency for gene-edited crops
7dResearchers at North Carolina State University call for a coalition of biotech industry, government and non-government organizations, trade organizations, and academic experts to work together to provide basic information about gene-edited crops to lift the veil on how plants or plant products are modified and provide greater transparency on the presence and use of gene editing in food supplies.
Molecular telegraphy: Precisely sending and receiving single molecules
7dThrowing and catching a ball is a familiar activity. But if the ball is replaced with something as tiny as a single molecule, is this task still possible? Can a single molecule be transferred to a specific, distant location, and then thrown back to the starting point? And how fast does it move? These questions were addressed by researchers from the University of Graz in collaboration with scientis
Researchers recommend more transparency for gene-edited crops
7dResearchers at North Carolina State University call for a coalition of biotech industry, government and non-government organizations, trade organizations, and academic experts to work together to provide basic information about gene-edited crops to lift the veil on how plants or plant products are modified and provide greater transparency on the presence and use of gene editing in food supplies.
Molecular telegraphy: Precisely sending and receiving single molecules
7dThrowing and catching a ball is a familiar activity. But if the ball is replaced with something as tiny as a single molecule, is this task still possible? Can a single molecule be transferred to a specific, distant location, and then thrown back to the starting point? And how fast does it move? These questions were addressed by researchers from the University of Graz in collaboration with scientis
Iconic Puerto Rico telescope to be dismantled amid collapse fears
7dThe iconic Arecibo radio telescope in Puerto Rico is to be dismantled, officials announce.
Antimicrobial peptides with anticancer properties
7dAnnouncing a new article publication for BIO Integration journal. In this article the authors Zhong, Cuiyu; Zhang, Lei; Huang, Jiandong; Huang, Songyin; Yao, Yandan from Sun Yat-sen University, Guangzhou, China; Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China and Shenzhen Institutes of Advanced Technology, Guangdong, China review antimicrobial peptides with antica
Insights in the search for new antibiotics
7dA collaborative research team from the University of Oklahoma, the Memorial Sloan Kettering Cancer Center and Merck & Co. published an opinion article in the journal, Nature Chemical Biology , that addresses the gap in the discovery of new antibiotics.
Algae breathe life into 3D engineered tissues
7d3D bioprinted algae can be harnessed as a sustainable source of oxygen for human cells in engineered vascularized tissues, researchers report. They embedded the bioprinted photosynthetic algae, along with human liver-derived cells, in a 3D hydrogel matrix to create honeycomb-shaped tissues with lobules, similar to the human liver.
The second-largest radio telescope in the world is shutting down
8dArecibo NSF Puerto Rico
The US National Science Foundation has just announced it is going to begin decommissioning the famous Arecibo Observatory, the 1,000-foot-wide, 900-ton radio telescope located in Puerto Rico. It's a huge blow to the astronomy community, which used Arecibo for 57 years to conduct an enormous amount of space and atmospheric research. What happened: Arecibo has withstood decades of wear and tear fro
Algae breathe life into 3D engineered tissues
8d3D bioprinted algae can be harnessed as a sustainable source of oxygen for human cells in engineered vascularized tissues, researchers report. They embedded the bioprinted photosynthetic algae, along with human liver-derived cells, in a 3D hydrogel matrix to create honeycomb-shaped tissues with lobules, similar to the human liver.
Curved origami provides new range of stiffness-to-flexibility in robots
8dCurved origami structures provide tunable flexibility to robots.
UK Officials: Useless Emails Are Killing the Planet
8dWarm Regards If you don't have anything to say, perhaps don't press "send." The massive number of useless emails sent every day apparently takes a substantial toll on the environment, the BBC reports . As a result, U.K. officials are expected to soon ask everyone to stop sending out messages unless they actually have something to say. Unfortunately, it's not clear that it will do much to save the
World-Renowned Arecibo Radio Telescope Set To Be Dismantled
8dArecibo has been a vital resource for radio astronomy, astrophysics, atmospheric studies and solar system astronomy. Now, it's set to close due to structural damage. (Image credit: Arecibo Observatory via AP)
Trump's E.P.A. Chief Plans 2 Foreign Trips Before Leaving Office
8dAndrew Wheeler, the head of the Environmental Protection Agency, looks to squeeze in two overseas trips in the Trump administration's last days.
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