Old Babylonian tablet likely used for surveying uses Pythagorean triples at least 1,000 years before Pythagoras An Australian mathematician has discovered what may be the oldest known example of applied geometry, on a 3,700-year-old Babylonian clay tablet. Known as Si.427, the tablet bears a field plan measuring the boundaries of some land. Continue reading…
Co-creator of the Oxford/AstraZeneca jab hopes it will inspire young girls to enter Stem careers Coronavirus – latest updates See all our coronavirus coverage Prof Sarah Gilbert has had quite a year. The co-creator of the Oxford/AstraZeneca jab has been made a dame, been given an emotional standing ovation at Wimbledon – and now a Barbie doll has been made in her honour. Gilbert, who led the deve
Around the Svalbard archipelago in the Arctic Ocean, rhodoliths made up of coralline red algae provide ecological niches for a wide variety of organisms. A team of researchers from Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), the University of Bayreuth and Senckenberg Research Institute in Wilhelmshaven has recently discovered a large quantity of microplastics in this ecosystem.
Engine Lock In the near future, you may need to prove to your car that you're sober before you're allowed to take the wheel. Buried on page 1,066 of the newest version of the infrastructure bill currently being debated by Congress is a provision, spotted by Motherboard , that says every new car built from 2027 onward would need to include some sort of monitoring system to catch anyone trying to d
Roll Out SpaceX is getting closer and closer to launching its first massive Starship prototype — into orbit, or at least in its general direction, if something happens to go wrong again . The Elon Musk-led space company just rolled out the first orbital-class prototype of its Super Heavy booster, a 230-foot rocket stage designed to hoist its 160-foot Starship spacecraft into space. pic.twitter.co
Nic spent most of her childhood avoiding people. She was raised by a volatile father and a mother who transferred much of the trauma she'd experienced onto her daughter. The combination left Nic fearful and isolated. "My primitive brain was programmed to be afraid of everybody, because everybody's evil and they're gonna hurt you, " she told me. (Nic asked to be referred to by only her first name
This article was published online on August 4, 2021. It's one of the darkest and bloodiest episodes in Ovid's Metamorphoses . King Tereus of Thrace, having lusted after his sister-in-law, Philomela, inveigles her away from her father's protection, takes her to a forest dungeon, and rapes her. Philomela, towering in eloquence, vows to tell the world what Tereus has done; her raised voice, she prom
"You'll want to read this," my wife said, handing me the Sunday Boston Globe . The cover story that week in late September 2020 was about a 62-year-old woman who had colon cancer that had metastasized. She died in a local hospital; her husband was also in poor health and could not take care of her at home. After she died, he moved into an area facility. Reading of someone so close to my own age s
A mysterious disease is killing off the West Coast's enormous sunflower sea star, so researchers have launched an ambitious effort to breed this species in captivity. (Image credit: Dennis Wise/University of Washington)
At the end of the 2020 election, California's Republicans had reason to feel hopeful. Although Joe Biden won the state by a landslide, Donald Trump won more votes (6 million) there than any other Republican candidate had ever. Increased Republican turnout led to victories in four competitive House races with large Latino populations. One of those districts even elected the state's first Republica
A team of investigators used enhanced carbon dating methods to examine human remains from the site in Peru A scientific discovery about Machu Picchu has cast doubt on the reliability of colonial records for modern western historians trying to piece together an understanding of the Inca people who built the site. For more than 75 years, many historians and scientists have worked on the assumption
Fire Beach New videos show how the devastating wildfires in southern Turkey are turning sandy beach resorts into a scene straight out of an apocalyptic movie. One video shows residents evacuating a beach while a massive wall of fire shoots gargantuan clouds of dark smoke high into the sky. Worldwide, wildfires have been devastating this year — and these videos could be a grim foreshadowing of wha
Crypto Bust It's no secret that the cryptocurrency world has a criminality problem . The technology is regularly being used to launder money, buy illegal contraband, and even demand ransom . In a sense, that's a core premise of blockchain tech: a hyper-libertarian dream of exchanging money and other assets without any form of government intervention. Now, The Verge reports that a libertarian cryp
Dan Caselden was up late on November 3, 2018, playing the video game Counter-Strike, when he made astronomy history. Every time he died, he would jump on his laptop to check in on an automated search he was running of NASA space telescope images. Suddenly, in the early hours of the morning, something bizarre popped into view. "It was very confusing," said Caselden. "It was moving faster than… S
If you've traveled internationally this summer and have had to navigate a labyrinth of COVID-19 tests, quarantines, health-authorization forms, and scarce flights to get there, you are one of the lucky ones. Many people have been unable to travel at all. Few would argue that governments ought to fully reopen travel now, especially with the threat of the Delta variant. But the haphazard, unilatera
Long Haul The US Navy is developing an uncrewed aircraft that can remain airborne for 90 days at a time thanks to massive solar panels on each of its wings, New Scientist reports . The aircraft, evocatively called Skydweller and built by US-Spanish aerospace company Skydweller Aero, could allow the Navy to keep a continuous eye on the surrounding seas while escorting ships months at a time, a maj
AI Unleashed United Nations delegates are currently meeting to debate possible regulations controlling autonomous killer robots — but Russia is having none of it. The Russian delegate, representing a country that has already developed and deployed military robots in real-world conflicts, remained steadfast that the global community doesn't need any new rules or regulations to govern the use of ki
No Hands! Tesla CEO Elon Musk reportedly had a huge disagreement with his engineers over a key aspect of the Model Y back when that was still being developed. The issue? Whether to include a key functionality that comes standard with every other vehicle on the market: a steering wheel. Musk, overconfident in Tesla's ability to create fully autonomous vehicles , reportedly wanted to do away with s
Every weekday evening, our editors guide you through the biggest stories of the day, help you discover new ideas, and surprise you with moments of delight. Subscribe to get this delivered to your inbox. Governor Andrew Cuomo of New York has always loved drawing attention to himself. This is, after all, the man who signed a contract for a book about his leadership during the coronavirus pandemic—e
SARS-CoV-2 nanobodies—microscopic molecules developed at the University of Pittsburgh School of Medicine that neutralize the virus in animals—are remarkably active against mutations found in variants, including Delta, according to new research by Pitt and Case Western Reserve University scientists.
Minister says JCVI experts to update advice 'imminently' on widening access to vaccine to more teenagers Coronavirus – latest updates See all our coronavirus coverage Covid vaccines are expected to be offered to children in the UK aged 16 and 17, in line with many other countries, after a minister confirmed government experts will update their advice "imminently". Michelle Donelan, the universiti
Teenagers in UK could be given green light for vaccine; US moratorium on evictions; Sydney man in his 20s dies from virus US Covid hospitalisations rise as doctors say patients are unvaccinated Nicola Sturgeon expects jab to be recommended for over-16s New York to require vaccination for indoor dining and events Hopes UK vaccine trial in pregnant women will allay jab fears See all our coronavirus
Updated at 9:55 a.m. ET on August 4, 2021. In the next few days and weeks, Americans will read headlines announcing all the lessons learned from Nina Turner's primary loss to Shontel Brown in Ohio's Eleventh Congressional District yesterday. Political writers might treat the race as a parable: a warning for progressives and an endorsement of the Democratic establishment's approach to politics. Tw
The movements of ancient crop and animal domesticates across prehistoric Eurasia are well-documented in the archaeological record. What is less well understood: How Bronze Age farmers and herders incorporated newly introduced domesticates—like cows from southwestern Asia—into their long-standing animal husbandry and culinary traditions.
Jeff Bezos is presumably fuming. His space company, Blue Origin, had initially contested NASA's decision in April to award SpaceX with the Human Landing System contract, a multi-billion agreement to build a lander capable of bringing the first astronauts to the surface of the Moon since the Apollo missions. In early May, NASA told SpaceX to cease all work on the contract after Blue Origin and Ala
Following Steven Weinberg's lead, we plunge further back into cosmic history, beyond the formation of atomic nuclei. Today, we discuss the origin of the quark-gluon plasma and the properties of the famous Higgs boson, the "God Particle." Is there a limit? How far can we go back in time? Last week , we celebrated the great physicist Steven Weinberg, bringing back his masterful book The First Three
X-ray imaging is a fast and painless way for doctors to see inside a person. But radiation detectors, which go under the body part being imaged, are rigid panels that contain harmful heavy metals, such as lead and cadmium. Now, researchers in ACS' Nano Letters report a proof-of-concept wearable X-ray detector prepared from nontoxic metal-organic frameworks (MOFs) layered between flexible plastic a
New York City will be the first city in the US to require proof of vaccination to enter a variety of indoor places, the city's mayor announced yesterday. Mayor Bill de Blasio told a press conference that starting September 13, the city will start requiring the proof at indoor venues like bars, restaurants, and gyms. The so-called Key to NYC Pass (which, rather confusingly, is a program, not an ac
An international team has observed an amazing phenomenon in a nickel oxide material during cooling: Instead of freezing, certain fluctuations actually increase as the temperature drops. Nickel oxide is a model system that is structurally similar to high-temperature superconductors. The experiment shows once again that the behavior of this class of materials still holds surprises.
Analysis: official advisers have called for jabs to be given to children aged 16 and 17 in a rethink of policy Coronavirus – latest updates See all our coronavirus coverage Just weeks ago, the Joint Committee on Vaccination and Immunisation (JCVI) recommended that children over the age of 12 should only be vaccinated if they were extremely vulnerable or lived with someone at risk, citing concerns
An international team of researchers has found evidence of multiple waves of ancient brown bears migrating to the Japanese island of Honshu over vast periods of time. In their paper published in the journal Royal Society Open Science, the group describes their genetic analysis of tissue recovered from a brown bear skull found near Tokyo, and what they learned from it.
Over the past 12 days of Olympic competition in and around Tokyo, records have been broken and dreams shattered as more than 11,500 athletes have put forward their best efforts, observed through the lenses of thousands of cameras. Collected here are images from the past week of the Tokyo 2020 Summer Olympics.
Delta cluster rises to 63 as Victoria records one new local case of coronavirus in a Melbourne teacher Follow our Covid live blog for the latest updates Qld hotspots ; Qld restrictons Updated national plan suggests 80% of eligible Australians could be fully vaccinated by end of 2021 Vaccine rollout tracker ; get our free news app ; get our morning email briefing Queensland has cancelled next Wedn
Democracy in ancient Athens looked quite different from democracies today. Instead of elections, most offices—including those in the legislature, governing councils, and magistrates—were filled by citizen volunteers, selected by random lottery. These citizens' assemblies drafted, debated, and passed laws; made major foreign policy decisions; and controlled military budgets.
New research led by NASA provides a closer look at a nearby star thought to resemble our young sun. The work allows scientists to better understand what our sun may have been like when it was young, and how it may have shaped the atmosphere of our planet and the development of life on Earth.
A New Zealand study claims men and women become more satisfied with their bodies over time – bucking the expectations of our youth-obsessed culture Name: Happy retirees. Age: Well, as you know, people retire at different ages, typically from about 60 onwards. Continue reading…
Last week, Senate negotiators released the text of the $1.2 trillion bipartisan infrastructure deal. For the first time since the deal was announced in June, we can actually see what's in it. On its face, this isn't a climate bill. It invests significantly in a federal road and highway system that encourages fossil-fuel-based travel in private cars and trucks. It also just does too little, making
For the average person, math seems to play little to no role in their day-to-day life. But, the fanciest gadgets and technologies are all heavily reliant on mathematics. Without advanced (and often obscure) mathematics, modern society would not be possible. The following is an adapted excerpt from the book What's the Use? It is reprinted with permission of the author and Hachette Book Group. What
Let's start with what harvestmen are not. They are not men, nor do they harvest; they probably get their name from the time of year they're commonly spotted, in late summer or early fall. Though eight-legged , they are not spiders, but they are part of the broader arachnid group, which also includes ticks and mites. And despite some truly slanderous rumors , they are not venomous and pose absolut
Boeing's Starliner won't launch Wednesday as had been planned following problems with its propulsion system that prevented a key uncrewed test flight to the international space station a day earlier—and it's not clear when the troubled spaceship will fly next.
Argentinian astronomers have conducted radio observations of a very-high-energy gamma-ray source known as HESS J1857+026. Results of this study provide new insights into the nature of this mysterious source. The research was detailed in a paper published July 27 on the arXiv pre-print server.
Neuroscientists have released the most detailed 3D map of the mammalian brain ever made, created from an animal whose brain architecture is very similar to our own—the mouse. The map and underlying data set, which are now freely available to the public , depict more than 200,000 neurons and half a billion neural connections contained inside a cube of mouse brain no bigger than a grain of sand. Th
Through job-matching platforms and AI-powered games and interviews, companies are relying more and more on artificial intelligence to streamline the hiring process. But some job seekers feel frustrated and misunderstood by these technologies. Malika Devaux is a student at the HOPE Program , a Brooklyn-based nonprofit that provides job training. Devaux is looking for a job, and we asked her to com
The average American eats roughly 22 teaspoons of added sugar a day — more than three times the recommended amount for women and more than double the recommended amount for men. Although this overconsumption is known to contribute to diabetes and other disorders, the exact ways in which eating too much sugar sets the stage for metabolic diseases on a cellular level has been less clear. Now, a tea
Extreme weather events seem to be getting more common. In the last month in particular, we've seen dramatic flash floods in various parts of the world, including Germany , China , and the US . But while some regions get an excess of rainfall, others are seeing a dearth of it. They're not all waiting for Mother Nature to show them some love, though. Scientists in the United Arab Emirates are takin
When it comes to hiring, it's increasingly becoming an AI's world—we're just working in it. In this, the final episode of Season 2 of our AI podcast "In Machines We Trust" and the conclusion of our series on AI and hiring, we take a look at how AI-based systems are increasingly playing gatekeeper in the hiring process—screening out applicants by the millions, based on little more than what they s
It's a most unlikely habitat and really has no creature comforts to recommend it. But University of Delaware researcher Julie Maresca and students in her lab are studying concrete and the life that stubbornly persists within.
Since its isolation in 2004 by Geim and Novoselov from the University of Manchester (Nobel Prize in Physics in 2010), graphene has been termed a 'wonder material' due to its exceptional properties, which have already been exploited in many applications and products. However, the use of graphene in the form of tiny flakes in polymer composites limits the full exploitation of its excellent propertie
A team of researchers from the University of Wisconsin, the Smithsonian Institution's National Museum of Natural History, and Western Connecticut State University, has assembled the first draft genome of Phalangium opilio—the daddy longlegs spider. In their paper published in Proceedings of the Royal Society B, the group describes clues they found that explain why the spider developed such long le
A novel route to tune and control the magnetic domain wall motions employing combinations of useful magnetic effects inside very thin film materials, has been demonstrated by researchers from Daegu Gyeongbuk Institute of Science and Technology (DGIST) in Korea. The research, published in the journal Advance Science, offers a new insights into spintronics and a step towards new ultrafast, ultrasmal
A new study has revealed changes in healthy lung tissue which indicate preparation to receive metastases. The changes were identified in the area known as 'the micro-environment' of the tumor, and specifically in connective tissue known as fibroblasts.
Adults infected with SARS-CoV-2 exhale different metabolites in their breath than uninfected people. Now, researchers have shown that children infected with SARS-CoV-2 also show breath metabolite changes, but they're largely different from the ones in adults. Someday, this information could be used to quickly and easily screen children for infection, the researchers say.
Research could lead to doctors being able to tell women how long they have got left to start a family A series of genetic signals that influences the age women begin menopause has been identified, potentially paving the way to fertility treatment that could extend the natural reproductive lifespan of women. Researchers scanned the genes of more than 200,000 women and found nearly 300 genetic sign
X-ray imaging is a fast and painless way for doctors to see inside a person. But radiation detectors, which go under the body part being imaged, are rigid panels that contain harmful heavy metals, such as lead and cadmium. Now, researchers report a proof-of-concept wearable X-ray detector prepared from nontoxic metal-organic frameworks (MOFs) layered between flexible plastic and gold electrodes fo
Some artists are embracing 3D printing as a new medium, allowing them to create intricate 3D compositions that are difficult to produce in any other way. But the rigid, plastic-based materials used in many 3D printers require high heat for workability. Now, researchers reporting in ACS Omega have developed a colorful new ink for 2D and 3D art made of mica pigments in alginate, a sugar from seaweed
An artificial pancreas could soon help people living with type 2 diabetes and who also require kidney dialysis. Tests show that the device can help patients safely and effectively manage their blood sugar levels and reduce the risk of low blood sugar levels.
Small electronics, including smartwatches and fitness trackers, aren't easily dismantled and recycled. So when a new model comes out, most users send the old devices into hazardous waste streams. To simplify small electronics recycling, researchers have developed a two-metal nanocomposite for circuits that disintegrates when submerged in water. They demonstrated the circuits in a prototype transie
Epstein Connection Even now, months after it was revealed that Bill Gates' relationship with Jeffrey Epstein was likely a driving factor in his divorce and a great source of personal turmoil, more troubling details about the duo continue to emerge. New reporting from Rolling Stone reveals a greater insight into the disgraced financier and convicted sex criminal's playbook for ingratiating himself
Researchers have developed a molecule that fluoresces where new tissue is forming in the body. Alongside helping to detect tumors, the molecule could play a significant role in research of wound healing disorders.
In a proof-of-concept study, researchers have created a coating that can be applied to endotracheal tubes and release antimicrobial peptides that target infectious bacteria with specificity. The innovation could reduce upper-airway bacterial inflammation during intubation, a situation that can lead to chronic inflammation and a condition called subglottic stenosis, the narrowing of the airway by a
Ask any space explorer, and they'll have a favorite photo or two from their mission. For Kevin Hand, a scientist at NASA's Jet Propulsion Laboratory in Southern California and co-lead of the Perseverance rover's first science campaign, his latest favorite is a 3D image of low-lying wrinkles in the surface of Jezero Crater. The science team calls this area "Raised Ridges." NASA's Ingenuity Mars Hel
Whole-genome sequencing efforts around the world have offered important insights into human diversity, historical migrations, and the relationships between people of different regions — but scientists still don't have a complete picture because some regions and people remain understudied. A new study helps to fill one of these big gaps by generating more than 100 high-coverage genome sequences fr
Scientists have identified nearly 300 gene variations that influence reproductive lifespan in women. Additionally, in mice, they have successfully manipulated several key genes associated with these variants to extend their reproductive lifespan. Their findings substantially increase our knowledge of the reproductive ageing process, as well as providing ways to improve the prediction of which wome
Since receiving a $25 million grant in 2019 to become the first National Science Foundation (NSF) Quantum Foundry, UC Santa Barbara researchers affiliated with the foundry have been working to develop materials that can enable quantum information-based technologies for such applications as quantum computing, communications, sensing, and simulation.
This week, NASA's airborne Oceans Melting Greenland (OMG) mission begins its final survey of glaciers that flow from Greenland into the ocean. OMG is completing a six-year mission that is helping to answer how fast sea level is going to rise in the next five, 10, or 50 years.
Air quality on Toronto subway platforms has improved substantially with the rollout of new cars on Line 1, according to a new study by the University of Toronto's Faculty of Applied Science & Engineering and Health Canada.
Some kinds of water pollution, such as algal blooms and plastics that foul rivers, lakes, and marine environments, lie in plain sight. But other contaminants are not so readily apparent, which makes their impact potentially more dangerous. Among these invisible substances is uranium. Leaching into water resources from mining operations, nuclear waste sites, or from natural subterranean deposits, t
Using data from two large, long-running study projects in the Puget Sound region — one that began in the late 1970s measuring air pollution and another on risk factors for dementia that began in 1994 — researchers identified a link between air pollution and dementia.
Ischemic stroke, which results in loss of neurological function, initiates a complex cascade of pathological events in the brain, largely driven by excitotoxic Ca2+ influx in neurons. This leads to cortical spreading depolarization, which induces expression of genes involved in both neuronal death and survival; yet, the functions of these…
Many zooplankton and fishes vertically migrate on a diel cycle to avoid predation, moving from their daytime residence in darker, deep waters to prey-rich surface waters to feed at dusk and returning to depth before dawn. Vertical migrations also occur in response to other processes that modify local light intensity,…
Defining protein–protein interactions (PPIs) in their native environment is crucial to understanding protein structure and function. Cross-linking–mass spectrometry (XL-MS) has proven effective in capturing PPIs in living cells; however, the proteome coverage remains limited. Here, we have developed a robust in vivo XL-MS platform to facilitate in-depth PPI mapping by…
Many complex networks depend upon biological entities for their preservation. Such entities, from human cognition to evolution, must first encode and then replicate those networks under marked resource constraints. Networks that survive are those that are amenable to constrained encoding—or, in other words, are compressible. But how compressible is a…
Family with sequence similarity 20C (Fam20C), the major protein kinase in the secretory pathway, generates the vast majority of the secreted phosphoproteome. However, the regulatory mechanisms of Fam20C transport, secretion, and function remain largely unexplored. Here, we show that Fam20C exists as a type II transmembrane protein within the secretory…
The regulator of capsule synthesis (Rcs) is a complex signaling cascade that monitors gram-negative cell envelope integrity. The outer membrane (OM) lipoprotein RcsF is the sensory component, but how RcsF functions remains elusive. RcsF interacts with the β-barrel assembly machinery (Bam) complex, which assembles RcsF in complex with OM proteins…
The concentration of atmospheric methane (CH4) continues to increase with microbial communities controlling soil–atmosphere fluxes. While there is substantial knowledge of the diversity and function of prokaryotes regulating CH4 production and consumption, their active interactions with viruses in soil have not been identified. Metagenomic sequencing of soil microbial communities enables…
Sitting in a static railway carriage can produce illusory self-motion if the train on an adjoining track moves off. While our visual system registers motion, vestibular signals indicate that we are stationary. The brain is faced with a difficult challenge: is there a single cause of sensations (I am moving)…
The transfer of topological concepts from the quantum world to classical mechanical and electronic systems has opened fundamentally different approaches to protected information transmission and wave guidance. A particularly promising emergent technology is based on recently discovered topolectrical circuits that achieve robust electric signal transduction by mimicking edge currents in…
Going beyond conventional approaches, researchers are using carefully cultured bacterial communities to improve sewage treatment—and create useful products in the process When it comes to the murky-looking water tanks in Kartik Chandran's laboratory, fume hoods are essential. Not only do the tanks get regular top-ups of sewage sludge and food…
New research links a close, supportive relationship with parents, especially fathers, at key points during adolescence with fewer adjustment issues. The researchers examined how "parental intimacy" in families with mothers and fathers affected the children's self-esteem, weight concerns, and depressive symptoms at different points across adolescence. They found that closeness with fathers had bro
Is organic farming the only alternative to conventional agriculture to promote biodiversity in agricultural landscapes? An international research team questions this. According to the authors, a landscape mosaic of natural habitats and small-scale and diverse cultivated areas is the key to promoting biodiversity on a large scale in both conventional and organic agriculture. They state that politic
Researchers at University of Notre Dame are developing an artificial neural network to read complex ancient handwriting based on human perception to improve capabilities of deep learning transcription.
Groups commonly targeted by voting restriction laws—those with low incomes, who are racial minorities, and who are young—are also less likely to be insured in states with more voting restrictions, according to a study by researchers at Columbia University Mailman School of Public Health and University of Alberta School of Public Health, Edmonton, Canada. However, those who are wealthier, white or
Polymer semiconductors—materials that have been made soft and stretchy but still able to conduct electricity—hold promise for future electronics that can be integrated within the body, including disease detectors and health monitors.
The human brain holds the secret to our unique personalities. But did you know that it can also form the basis of highly efficient computing devices? Researchers recently showed how to do this, through graphene-diamond junctions that mimic some of the human brain's functions.
Recent record-breaking rainfall across the northeastern United States is part of a larger trend. From Maine to West Virginia, the Northeast has seen an abrupt increase in extreme precipitation—heavy rain and snow resulting in about 1 to 2 inches of water in a day depending on location since 1996, which has coincided with warming sea surface temperatures in the North Atlantic. Northeast extreme pre
Sand and mud subducted off the coast of California around 75 million years ago returned to the Earth's crust by rising up through the mantle as enormous diapirs, like blobs in a lava lamp, new research shows.
Researchers have developed a new way to detect a potentially life-threatening condition that can occur during pregnancy. The condition, placenta accreta spectrum disorder, occurs when the placenta grows too deeply into the uterine wall and fails to detach from the uterus after childbirth. It can lead to significant blood loss during pregnancy and delivery, requiring blood transfusions and intensiv
The study of RNA modifications in large clinical cohorts can reveal relationships between the epitranscriptome and human diseases, although this is especially challenging. We developed ModTect ( https://github.com/ktan8/ModTect ), a statistical framework to identify RNA modifications de novo by standard RNA-sequencing with deletion and mis-incorporation signals. We show that ModTect can identify
DNA double-strand break (DSB) repair is initiated by MRE11 nuclease for both homology-directed repair (HDR) and alternative end joining (Alt-EJ). Here, we found that GRB2, crucial to timely proliferative RAS/MAPK pathway activation, unexpectedly forms a biophysically validated GRB2-MRE11 (GM) complex for efficient HDR initiation. GRB2-SH2 domain targets the GM complex to phosphorylated H2AX at DS
Posttranscriptional gene silencing (PTGS) is a regulatory mechanism to suppress undesired transcripts. Here, we identified Flowering locus VE ( FVE ), a well-known epigenetic component, as a new player in cytoplasmic PTGS. Loss-of-function fve mutations substantially reduced the accumulation of transgene-derived small interfering RNAs (siRNAs). FVE interacts with suppressor of gene silencing 3 (S
Eukaryotic initiation factor 4A-III (eIF4A3), a core helicase component of the exon junction complex, is essential for splicing, mRNA trafficking, and nonsense-mediated decay processes emerging as targets in cancer therapy. Here, we unravel eIF4A3's tumor-promoting function by demonstrating its role in ribosome biogenesis (RiBi) and p53 (de)regulation. Mechanistically, eIF4A3 resides in nucleoli
Cement is the most produced material in the world. A major player in greenhouse gas emissions, it is the main binding agent in concrete, providing a cohesive strength that rapidly increases during setting. Understanding how such cohesion emerges is a major obstacle to advances in cement science and technology. Here, we combine computational statistical mechanics and theory to demonstrate how ceme
We investigated the influence of Bacillus Calmette-Guérin (BCG) vaccination on the unstimulated plasma levels of a wide panel of cytokines, chemokines, acute-phase proteins (APPs), matrix metalloproteinases (MMPs), and growth factors in a group of healthy elderly individuals (age, 60 to 80 years) at baseline (before vaccination) and 1 month after vaccination as part of our clinical study to exami
Cointegration of multistate single-transistor neurons and synapses was demonstrated for highly scalable neuromorphic hardware, using nanoscale complementary metal-oxide semiconductor (CMOS) fabrication. The neurons and synapses were integrated on the same plane with the same process because they have the same structure of a metal-oxide semiconductor field-effect transistor with different function
Slow slip events (SSEs) represent a slow faulting process leading to aseismic strain release often accompanied by seismic tremor or earthquake swarms. The larger SSEs last longer and are often associated with intense and energetic tremor activity, suggesting that aseismic slip controls tremor genesis. A similar pattern has been observed for SSEs that trigger earthquake swarms, although no compara
Heliconius butterflies have undergone adaptive radiation and therefore serve as an excellent system for exploring the continuum of speciation and adaptive evolution. However, there is a long-lasting paradox between their convergent mimetic wing patterns and rapid divergence in speciation. Here, we characterize a locus that consistently displays high divergence among Heliconius butterflies and act
Fisheries encompass complex interplays between social, economic, and environmental factors, but limitations on historical fisheries data can hamper efforts to identify and contextualize the long-term spatiotemporal patterns that shape them. We integrate 2500 years of stable isotope ( 34 S, 13 C, and 15 N) and zooarchaeological evidence from Gulf of Mexico fisheries to assess cultural, demographic
Efficient energy transport is desirable in organic semiconductor (OSC) devices. However, photogenerated excitons in OSC films mostly occupy highly localized states, limiting exciton diffusion coefficients to below ~10 –2 cm 2 /s and diffusion lengths below ~50 nm. We use ultrafast optical microscopy and nonadiabatic molecular dynamics simulations to study well-ordered poly(3-hexylthiophene) nanof
Direct CO 2 hydrogenation to methanol using renewable energy–generated hydrogen is attracting intensive attention, but qualifying catalysts represents a grand challenge. Pure-/multi-metallic systems used for this task usually have low catalytic activity. Here, we tailored a highly active and selective InNi 3 C 0.5 /ZrO 2 catalyst by tuning the performance-relevant electronic metal-support interac
Determining the presence or absence of a past long-lived lunar magnetic field is crucial for understanding how the Moon's interior and surface evolved. Here, we show that Apollo impact glass associated with a young 2 million–year–old crater records a strong Earth-like magnetization, providing evidence that impacts can impart intense signals to samples recovered from the Moon and other planetary b
Host antibody responses are pivotal for providing protection against infectious agents. We have pioneered a new class of self-assembling micelles based on pentablock copolymers that enhance antibody responses while providing a low inflammatory environment compared to traditional adjuvants. This type of "just-right" immune response is critical in the rational design of vaccines for older adults. H
Nature, Published online: 04 August 2021; doi:10.1038/d41586-021-02128-y Study provides hints about the factors that govern reproductive lifespan — and how they could eventually be harnessed to extend fertility.
The number of people exposed to floods worldwide has surged almost a quarter over the last two decades, according to satellite-based data that shows an additional 86 million now live within flood-prone regions.
Researchers from Johns Hopkins Medicine say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals. Their experiments working with mice and fruit flies, however, found that the gene for CaMKII also contributes to an evolutionary tradeoff: increased susceptibility to age-associated diseases, frailty and mortality.
Pour One Out Last week, Russia's Pirs module was retired and detached from the International Space Station, one month before its 20th work anniversary. As it fell back to the Earth, space station crew members got to watch a six-minute light show as the module incinerated and broke apart in the atmosphere like a slow-burning shooting star, according to Space.com . Thankfully, for those of us who d
Researchers from Columbia University, University of Southern California, and Sotheby's published a paper in the Journal of Marketing that introduces a new tool that measures the relevance of academic marketing articles to marketing practice, both in terms of topical and timely relevance.
New research provides a closer look at a nearby star thought to resemble our young Sun. The work allows scientists to better understand what our Sun may have been like when it was young, and how it may have shaped the atmosphere of our planet and the development of life on Earth.
Mutually beneficial relationships are common, but what happens when one partner stops enforcing the other's good behavior? An exception to the usual relationship between figs and their pollinator-wasps, may hold the answer.
Scientists have identified two proteins that could be used for a potential vaccine against nontypeable Haemophilus influenzae (NTHi). Working in a mouse model, the investigators found that administering two bacterial adhesive proteins that play a key role in helping the bacteria to latch on to respiratory cells and initiate respiratory tract infection stimulated protective immunity against diverse
Researchers have developed unique, interactive, 3D narrated diagrams to help students learn about the structure and function of perceptual systems in the human brain. A new study exploring how students responded to these lessons on desktop PCs and in virtual reality (VR) offers new insights into the benefits of VR as an educational tool.
An experiment finds that even generous people are willing to steal half the earnings of a large group if their personal gain exceeds 100 euro, report researchers. In the recent years, the general public has steadily lost confidence in financial institutions, economic authorities, and corporate managers in particular. People hold a view that key economic actors will do anything for profits, includ
A system in the brain used in the processing of information and the storing of memories works similarly to railroad switches controlling a train's destination, researchers report. The findings offer new insights into how the brain functions and reveal coordination the brain uses to avoid neurological clashes. "Researchers have sought to identify neural circuits that have specialized functions, bu
Deploying residential heat pumps more widely across the United States has the potential to help reduce carbon pollution while also saving homeowners money, according to a new study. However, in most parts of the country the electricity grid will have to get cleaner and electric heat pumps will have to get cheaper before these devices become both environmentally and financially compelling, says Pa
Researchers are comprehensively surveying the short RNA molecules that regulate genome function during embryonic development. Information gained from human ova and embryos helps to understand problems occurring during pregnancy and develop increasingly effective infertility treatments.
Farmers around the world rely on antibiotics to keep livestock healthy, but increased bacterial resistance has created problems for both animals and humans. Instead of expensive new drugs, scientists have found a potential affordable solution that comes from nature. A new article in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society, details how bacteriophages co
Many students have been out of their classrooms for a year and a half, and though this fall is shaping up to be more "normal," there are still plenty of questions about what back to school will look like. Gearing up for this year's back-to-school season means thinking about a lot more than notebooks and highlighters. "We may be quarantined at different times or back to e-learning. We may or may n
To better estimate flood risks, risk maps should also consider historical data. This is recommended by researchers of CEDIM—Center for Disaster Management and Risk Reduction Technology of Karlsruhe Institute of Technology (KIT). CEDIM has now presented its first report on the flood disaster in Rhineland-Palatinate and North Rhine-Westphalia. As regards the role of climate change, the combination o
Empathetic people generally make better leaders, previous management research has shown, but there is one critical area where they might struggle compared to leaders who have lower levels of empathy—giving negative feedback.
DNA testing is one of modern medicine's most significant breakthroughs. Today, anyone can receive personalized information about their genes and ancestry with just a little saliva. Now, a Seattle-based company is working to bring equally deep analysis to another set of complicated molecules in humans: the trillions of proteins circulating within our bodies.
Losses of important eelgrass meadows in western Sweden since the 1980s have led to considerable bottom erosion and the release of carbon and nitrogen; substances that contribute to increasing climate change and eutrophication.
Even as climate change and urbanization make floods more frequent and their consequences more severe, a higher proportion of people are living in areas that experience them. In a new study published today in Nature, researchers used satellite images to map over 900 flood events that occurred between 2000 and 2018, affecting between 255 million and 290 million people. And while the global populati
Nature, Published online: 04 August 2021; doi:10.1038/d41586-021-02149-7 Satellite imaging has shown population increases are 10x higher in flood prone areas than previously thought, and a new way to introduce fairness into a democratic process.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03706-w High-resolution observations confirm that Jupiter's global upper atmosphere is heated by transport of energy from the polar aurora.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03682-1 A macroscopic analogue of a spin system is shown to emerge in an ensemble of droplets bouncing on the surface of a vibrating bath, revealing symmetry-breaking phenomena such as 'magnetic' ordering.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03779-7 Hundreds of genetic loci associated with age at menopause, combined with experimental evidence in mice, highlight mechanisms of reproductive ageing across the lifespan.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03789-5 The cryo-electron microscopy structure of a newly identified, early spliceosomal complex reveals the mechanism by which the RNA helicase Prp5 enhances the fidelity of the excision of introns from precursor mRNAs.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03683-0 A back-bending band structure and an emerging pseudogap are observed at the interface between a crystalline solid (black phosphorus) and disordered alkali-metal dopants.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03747-1 Analyses of samples from 728 women with uterine leiomyomas (uterine fibroids), and public data, show that somatic and germline mutations in the SRCAP histone-loading complex genes are associated with the condition.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03695-w Satellite imagery for the period 2000–2018 reveals that population growth was greater in flood-prone regions than elsewhere, thus exposing a greater proportion of the population to floods.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03782-y The cryo-electron microscopy structure of mouse MFSD2A sheds light on the mechanism that underlies its lipid transport functions, which have a pivotal role in regulating the blood–brain barrier.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03787-7 A meta-analysis of studies in which bees were exposed to combinations of agrochemicals, nutritional stressors and/or parasites revealed evidence for synergistic effects on mortality when bees were exposed to multiple agrochemicals at field-realistic levels.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03688-9 Nonlinearity is shown to induce quantized topological transport via soliton motion; specifically, we demonstrate nonlinear Thouless pumping of photons in waveguide arrays with a non-uniformly occupied energy band.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03794-8 Structural and functional analysis of an insect olfactory receptor shed light on how receptors can be activated by diverse odorants.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03542-y This Review discusses how the activity of retrotransposons influences ageing and the role of these mobile genetic elements in age-related diseases and their treatment.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03778-8 Serial-section electron microscopy is used to reconstruct the full brain connectome of eight individual Caenorhabditis elegans at various stages of development, providing insight into the principles underlying brain maturation.
Nature, Published online: 04 August 2021; doi:10.1038/s41586-021-03788-6 Principles from the field of fair division are used to develop selection algorithms for citizens' assemblies that produce panels that are representative of the population while simultaneously selecting individuals with near-equal probabilities.
Nature, Published online: 04 August 2021; doi:10.1038/d41586-021-02079-4 Pollinators are under threat. A meta-analysis reveals that the combination of agrochemicals, parasites and malnutrition has a cumulative negative effect on bees, and that pesticide–pesticide interactions increase bee mortality.
Nature, Published online: 04 August 2021; doi:10.1038/d41586-021-01710-8 A broad analysis has identified genetic variants that influence age at natural menopause. The results implicate mechanisms such as DNA-damage repair and give insights into the potential for predicting and treating early menopause.
Nature, Published online: 04 August 2021; doi:10.1038/d41586-021-02006-7 An innovative algorithm provides a way of fairly selecting representative individuals for citizens' assemblies to learn about and deliberate on certain topics. Such groups hold promise for closing the gap between democracy and expertise.
Nature, Published online: 04 August 2021; doi:10.1038/d41586-021-02077-6 Experiments show that a collection of bouncing fluid droplets can behave like a microscopic system of spins — the intrinsic angular momenta of particles. This discovery could lead to a better understanding of the physics of spin systems.
Nature, Published online: 04 August 2021; doi:10.1038/d41586-021-01974-0 Satellite imaging combined with population data shows that, globally, the number of people living in flood-prone areas is growing faster than is the number living on higher ground — greatly increasing the potential impact of floods.
Nature, Published online: 04 August 2021; doi:10.1038/d41586-021-02005-8 A previously unknown subgroup of uterine fibroid tumours is driven by mutations that result in disruption of the DNA–protein complex chromatin. The findings could inform the management of this common condition.
Nature, Published online: 04 August 2021; doi:10.1038/d41586-021-02076-7 In insects, odorant receptor proteins form membrane ion channels that open on binding to an odorant molecule. The structures of an inactive and an active channel lend insights into how insects detect and distinguish between odours.
Russian literature has a knack for precisely capturing and describing the human condition. Fyodor Dostoevsky, Leo Tolstoy, and Aleksandr Solzhenitsyn are among the greatest writers who ever lived. If you want to be a wiser person, spend time with the great Russian novelists. In Fyodor Dostoevsky's 1864 novella Notes from Underground , an unnamed narrator asks the following question: "What can be
We live in a call-out culture, says activist and scholar Loretta J. Ross. You're probably familiar with it: the public shaming and blaming, on social media and in real life, of people who may have done wrong and are being held accountable. In this bold, actionable talk, Ross gives us a toolkit for starting productive conversations instead of fights — what she calls a "call-in culture" — and shar
Researchers are taking advantage of hydras' transparency to manipulate the remarkably resilient creatures in just about every possible way to learn how they sense touch. The new comprehensive analysis of hydra is a small step toward understanding neural networks in all living creatures. Hydra vulgaris , freshwater cnidarians that look like miniature jellyfish polyps, expand and contract as they n
A team of researchers from Villanova University, the Thackeray Wildlife Foundation and Museu de História Natural e da Ciência da Universidade do Porto has found evidence that the African house gecko made its way to the New World by riding aboard slave trading ships hundreds of years ago. In their paper published in the journal Royal Society Open Science, the group describes their DNA analysis of g
Is organic farming the only alternative to conventional agriculture to promote biodiversity in agricultural landscapes? An international research team led by the University of Göttingen questions this. According to the authors, a landscape mosaic of natural habitats and small-scale and diverse cultivated areas is the key to promoting biodiversity on a large scale in both conventional and organic a
A University of Wyoming professor has used computer modeling to propose that sand and mud subducted off the coast of California around 75 million years ago returned to the Earth's crust by rising up through the mantle as enormous diapirs, like blobs in a lava lamp.
Earlier this month, New York City and other cities along the east coast experienced some of the worst air pollution in the world. The cause? Wildfires in California and Oregon so large they produced smoke that drifted thousands of miles. If smoke that dense can travel from one end of the U.S. to the other, imagine what it could do to your lungs.
They look simple enough, light gray and about the size of a loaf of bread. On their face, a label sports a colorful "C" stylized to resemble a molecular structure along with the words "Carbon Census at USC."
Stream Full Episodes of Deadliest Catch: discovery+ ► https://www.discoveryplus.com/show/deadliest-catch Discovery ► https://go.discovery.com/tv-shows/deadliest-catch/ Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Follow Us on TikTok: https://www.tiktok.com/@Discovery We're on Instagram! https://instagram.com/Discovery Join Us on Facebook: https://www.facebook.com/Discovery Follow Us o
Space engineers will analyze whether a glitch that caused the International Space Station to spin out of its normal orientation could have impacted any of its systems, a Russian space official said Wednesday.
Giant bird-eating centipedes may sound like something out of a science-fiction film—but they're not. On tiny Phillip Island, part of the South Pacific's Norfolk Island group, the Phillip Island centipede (Cormocephalus coynei) population can kill and eat up to 3,700 seabird chicks each year.
Researchers at ETH Zurich have developed a molecule that fluoresces where new tissue is forming in the body. Alongside helping to detect tumors, the molecule could play a significant role in research of wound healing disorders.
Roadside ditches are a catchall for water, from both sheets of rain that fall on roads and runoff from lawns or fields. Although ditches are ubiquitous in the landscape, they have the potential to be much more than a storm water conduit. In fact, ditches are human-made lowlands that often act as wetlands, complete with fluctuating water levels and a broad array of vegetation and microbes.
A CRISPR-Cas9 variant with deactivated DNA-cutting function—known as "dCas9"—is a powerful tool to help researchers understand what genes do when their expression is dialed up or down, but it has some limitations.
Losses of important eelgrass meadows in western Sweden since the 1980s have led to considerable bottom erosion and the release of carbon and nitrogen; substances that contribute to increasing climate change and eutrophication. This is shown in a new study by researchers at the University of Gothenburg, Stockholm University, Åbo Akademi University and the University of Southern Denmark, published i
When animals become parents, they often need to change their behaviors in ways that allow them to protect and ensure the survival of their offspring. What happens in the brain when an animal becomes a new parent?
No link currently exists proving climate change is driving migration out of East Africa, despite a widespread acceptance that human mobility is a key impact of climate change, according to research today from a multi-disciplinary Oxford University team, which maintains the factors driving migration are complex.
Small electronics, including smartwatches and fitness trackers, aren't easily dismantled and recycled. So when a new model comes out, most users send the old devices into hazardous waste streams. To simplify small electronics recycling, researchers reporting in ACS Applied Materials & Interfaces have developed a two-metal nanocomposite for circuits that disintegrates when submerged in water. They
Researchers from Skoltech, KTH Royal Institute of Technology, and Uppsala University have predicted the existence of antichiral ferromagnetism, a nontrivial property of some magnetic crystals that opens the door to a variety of new magnetic phenomena. The paper was published in the journal Physical Review B.
Shortly after it formed, the moon was covered in a global ocean of molten rock (magma). As the magma ocean cooled and solidified, dense minerals sank to form the mantle layer, while less-dense minerals floated to form the surface crust. Later intense bombardment by massive asteroids and comets punched through the crust, blasting out pieces of mantle and scattering them across the lunar surface.
The Perseid meteor shower reaches its peak on the night of 11–12 August, giving skywatchers a potentially impressive summer treat. The meteors are best viewed from the northern hemisphere, and in ideal conditions with no clouds observers could see up to 50 an hour.
Emirati national Aisha Al Yazeedi, a research scientist at the NYU Abu Dhabi (NYUAD) Center for Astro, Particle, and Planetary Physics, has published her first research paper, featuring some key findings on the evolution of galaxies.
This map shows the temperature of the land surface on 2 August 2021. It is clear to see that surface temperatures in Turkey and Cyprus have reached over 50°C, again. A map we published on 2 July shows pretty much the same situation. The Mediterranean has been suffering a heatwave for some weeks, leading to numerous wildfires. Turkey, for example, is reported to be amid the country's worst blazes i
Researchers from Western Sydney University and CSIRO, Australia's national science agency, have discovered strange clouds of electrons surrounding galaxies deep in the cosmos. The clouds, which are about a billion light years away and never been seen before, resemble two ghosts dancing.
One of the constant challenges in education is keeping the learner engaged, motivated and connected in a world increasingly filled with distractions. Social media, streaming TV and video games all compete for students' increasingly fragmented attention.
New research by Surrey's Nuclear Physics Group has shown that it's possible to mimic excited quantum states with exotic nuclei, opening up a host of opportunities for next generation radioactive beam facilities, such as the Facility for Rare Isotope Beams (FRIB).
I'm currently training to become Australia's first woman astronaut. I expect to fly my first suborbital mission sometime in 2023 as a payload specialist on a commercial mission. In other words, I'll be one of few certified crew members who can handle specialized scientific equipment aboard a suborbital spacecraft.
Teams from the Chair of Plant Physiology at Technische Universität Dresden and the Julius Kühn Institute in Braunschweig have been researching biological methods to better control the widespread plant disease 'clubroot' in rapeseed in a joint project. They were able to observe an increase in fresh weight in infected plants through the addition of the fungus Acremonium alternatum. This is a promisi
A research team led by Prof. Dr. Michael Sommer, Professorship of Polymer Chemistry at Chemnitz University of Technology, and PD Dr. Michael Walter, project leader at the Cluster Of Excellence Living, Adaptive, and Energy-autonomous Materials Systems (livMatS) at the University of Freiburg, has succeeded in constructing a new dye molecule from the area of so-called mechanophores.
Record-breaking heat waves and drought have left West Coast rivers lethally hot for salmon, literally cooked millions of mussels and clams in their shells and left forests primed to burn. The extraordinary severity of 2021's heat and drought, and its fires and floods, has many people questioning whether climate change, fueled by human actions, is progressing even faster than studies have predicted
Emperor penguins thrive on Antarctica's coastlines in icy conditions any human would find extreme. Yet, like Goldilocks, they have a narrow comfort zone: If there's too much sea ice, trips to bring food from the ocean become long and arduous, and their chicks may starve. With too little sea ice, the chicks are at risk of drowning.
Researchers, including a North Carolina State University zoologist, found in a new study that three species of weasels once common in North America are likely in decline, including a species that's considered the world's smallest carnivore.
For over ten years, public inquiries, press reports, police whistleblowers—and even chief constables—have been raising the issue of police IT systems not being fit for purpose and ultimately failing victims of crime. This has prompted significant media attention and public scrutiny, as well as the resignation of the head of one force.
The world has become interconnected at a level we never before imagined possible. States, banking, communications, transport, tech and international development organizations have all embraced digital identification. The current conversation hinges on the need to speed up registrations to ensure that every person on this planet has their own digital ID.
Den britiske regering vurderer, at den konceptuelle fjerdegenerationsreaktor HTGR har mest potentiale som et demonstrationsprojekt, fordi designet genererer »ekstremt høje temperaturer«, der blandt andet kan udnyttes til at producere brint og fjernvarme.
The equity in your home, when used correctly, can be a powerful tool in reaching your financial goals. And countless homeowners are looking to take advantage of today's booming housing market. There are numerous ways to get cash for your home equity, including home loans and HELOCs. But a third option is a home equity investment which gives you cash today in exchange for a portion of the future v
LEDs are commonly used for sterilization—you may be using one to clean your electric toothbrush, for example. In the continued effort to combat the coronavirus pandemic, LEDs can also help inactivate SARS-CoV-2.
Parkträff med quiz och grillning! Plats: Pildammsparken i Malmö (närmare platsangivelse kommer inom kort) Vi träffas utomhus, håller avstånd på säkert sätt och pratar vetenskap och skepticism. Barnvänligt! Grillmöjligheter finns, … Continued Inlägget dök först upp på Vetenskap och Folkbildning .
New Zealand's endemic tuatara (Sphenodon punctatus) are the sole survivors of an ancient reptile order called Rhynchocephalia. Once widespread across New Zealand, tuatara survive in only a fraction of their historic range, on small offshore islands and in fenced eco-sanctuaries.
In a non-COVID year, Australia's vineyards host more than eight million wine tourists. While these visitors benefit wine producers and regional communities, they also generate a substantial amount of greenhouse gases.
Modern weather forecasts and climate studies rely heavily on computer simulations implementing physical models. These models need to make cohesive large-scale predictions but also include enough small-scale detail to be relevant and actionable. Given the enormous physical complexity of weather systems and the climate, realistic stochastic simulation of hydroenvironmental events in space and time,
A quick way to identify the "nth" friends of social media users based on spatial data mining of profiles and behavior on a service such as Twitter is described in the International Journal of Advanced Intelligence Paradigms.
The research team led by Prof. Huang Weixin and Assoc. Prof. Zhang Wenhua from University of Science and Technology of China of the Chinese Academy of Sciences, collaborating with Prof. Wang Ye from Xiamen University, investigated on the water gas shift (WGS) and CO hydrogenation reactions.
Driven by strict reservation policy and contiguous aggressive anthropogenic activities, the continental coastal wetlands in the reserve area of NE Italy show the polarization phenomenon, according to a study conducted by the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Science.
Since 2011, the United Nations has continually targeted, and largely failed to realize, greater road safety on a global scale. Road deaths are, in fact, increasing. Road safety efforts are nothing new to Japan, which has been conducting seasonal, nationwide education and enforcement campaigns since 1952.
A virtual private network (VPN) helps protect your privacy by routing all your internet traffic through an encrypted connection to a remote server. However, each VPN has its own tools and features to protect you, so you should choose the service that best meets your needs. For a limited time, take your pick from these ten VPN deals, now 30% off with code ANNUAL30. FastestVPN: Lifetime Subscriptio
Der er et stort potentiale for at forbedre tilværelsen for tusindvis af personer med Downs syndrom verden over, siger professor Jacob Sten Petersen fra Novo Nordisk. Det viser resultaterne af et samarbejde mellem danske forskere og en patientforening.
In Bangladesh's coastal districts — including Khulna, Satkhira, and Bagerhat — the effects of climate change have made the water so salty that it can no longer be used for drinking or for other domestic purposes. According to one study, some 70 percent of local residents now depend on water in distant ponds.
Nature Communications, Published online: 04 August 2021; doi:10.1038/s41467-021-25031-6 Precipitation hardening, used as an effective strengthening strategy in various alloy systems, has been usually achieved by coherent precipitates. Here, the authors develop ultrastrong ductile alloys employing structurally dissimilar semicoherent precipitates by shear band-driven precipitation.
Nature Communications, Published online: 04 August 2021; doi:10.1038/s41467-021-24993-x Epithelial cells that organise into structures that contain a lumen are polarised. Here, the authors show that the short intracellular domain of transmembrane protein CD13 is required to capture endosomes at the apical site and is required for the polarisation of cells.
Nature Communications, Published online: 04 August 2021; doi:10.1038/s41467-021-25055-y Bacterial adaptation through frame-shifting insertions and deletions (indels) could be reversed by secondary introduction of a frame-restoring indel. Here, the authors develop ScarTrek, a program that scans genomic data for different indels, and analyze 5977 clinical M. tuberculosis isolates for indel frequenc
Nature Communications, Published online: 04 August 2021; doi:10.1038/s41467-021-25065-w During wound healing and infection in the skin there is a hypoxic environment involving HIF-1α and NK cells. Here the authors show that NK cells through HIF-1α provide a cross-regulatory balance to provide an adequate antimicrobial defence that can inhibit subsequent wound healing.
Nature Communications, Published online: 04 August 2021; doi:10.1038/s41467-021-25006-7 Grouping T-cell receptors (TCRs) by sequence similarity could lead to new immunological insights. Here, the authors propose a tool that allows the rapid clustering of millions of TCR sequences, identifying TCRs potentially associated with the response to cancer, infectious and autoimmune diseases.
Nature Communications, Published online: 04 August 2021; doi:10.1038/s41467-021-25061-0 Single-atom Rh catalysts present superior activity in olefins hydroformylation, yet with limited success in regioselectivity control. Here the authors develop a Rh1 single-atom catalyst with nanodiamond as support, with which good to excellent regioselectivities to branched aldehydes in hydroformylation of ter
Nature Communications, Published online: 04 August 2021; doi:10.1038/s41467-021-25019-2 The linkage between temperature change and extinction rates in the fossil record is well-known qualitatively but little explored quantitatively. Here the authors investigate the relationship of marine animal extinctions with rate and magnitude of temperature change across the last 450 million years, and identi
Nature Communications, Published online: 04 August 2021; doi:10.1038/s41467-021-24964-2 Ribosome biogenesis is crucially dependent on proper rRNA folding, a process assisted by chaperones. Here the authors reveal how Puf6 promotes correct rRNA folding at low temperature, a condition where mis-paired RNA folding intermediates frequently accumulate.
Material som kan suga upp mycket stora mängder vätska, i till exempel blöjor, tillverkas av fossil petroleumolja. Forskare från SLU och KTH har tagit fram vete- och potatisbaserade material med liknande egenskaper. Många småbarnsföräldrar tänker på hälsa och miljö i samband med inköp till sina barn. Vad de ofta inte är medvetna om är att den stora miljöboven vid användning av engångsblöjor är de
The southernmost port in Louisiana is a key place for the U.S. energy industry, but also one of the most vulnerable places in the nation. Port Fourchon in Lafourche Parish serves 90% of the Gulf of Mexico's deepwater oil and gas activities, which is why the U.S. Naval Research Laboratory has invested $25 million in LSU to create a digital dome protecting Port Fourchon and the Louisiana Offshore Oi
Exceptionally hot and dry weather this summer has fueled dozens of wildfires across the western U.S., spewing smoke across the country and threatening to register yet another record-breaking year. More than a century of fire exclusion has created dense forests packed with excess trees and brush that ignite and spread fires quickly under increasingly warm and dry conditions.
As the world staggers through another summer of extreme weather, experts are noticing something different: 2021′s onslaught is hitting harder and in places that have been spared global warming's wrath in the past.
Recently, a pair of NASA studies identified the most likely locations to find pieces of the Moon's mantle on the surface, providing a map for future lunar sample return missions such as those under NASA's Artemis program. If collected and analyzed, these fragments from deep within the Moon can provide a better understanding of how the Moon, the Earth, and many other solar system worlds evolved.
Scientists studied microorganisms from an underwater mountain in the Atlantic Ocean, pioneering a method that could open new windows into our understanding of how life survives deep under the sea — or in space.
Seeing the urgent need for change, a team of scientists from leading research universities, conservation organizations and government laboratories across the West has produced a synthesis of the scientific literature that clearly lays out the established science and strength of evidence on climate change, wildfire and forest management for seasonally dry forests. The goal is to give land managers
A new study provides valuable new data that highlights how species extinction risk is accelerating due to rapid climate change and an increase in extreme climate events, such as glacial calving and sea ice loss.
Researchers report that infantile spasms, a rare but serious seizure disorder in babies, appear to be the result of a molecular pathway gone awry. In their study of a mouse model of the disorder, the researchers discovered that genetic mutations associated with the disease impair a pathway that is involved in building new synapses in the hippocampus, a brain region essential to learning and memory
BioNyt Videnskabens Verden (www.bionyt.dk) er Danmarks ældste populærvidenskabelige tidsskrift for naturvidenskab. Det er det eneste blad af sin art i Danmark, som er helliget international forskning inden for livsvidenskaberne.
Bladet bringer aktuelle, spændende forskningsnyheder inden for biologi, medicin og andre naturvidenskabelige områder som f.eks. klimaændringer, nanoteknologi, partikelfysik, astronomi, seksualitet, biologiske våben, ecstasy, evolutionsbiologi, kloning, fedme, søvnforskning, muligheden for liv på mars, influenzaepidemier, livets opståen osv.
Artiklerne roses for at gøre vanskeligt stof forståeligt, uden at den videnskabelige holdbarhed tabes.