Before the availability of artificial light, moonlight was the only source of light sufficient to stimulate nighttime activity; still, evidence for the modulation of sleep timing by lunar phases is controversial. Here, we use wrist actimetry to show a clear synchronization of nocturnal sleep timing with the lunar cycle in participants living in environments that range from a rural setting with an

When severely or chronically injured, the liver loses its ability to regenerate. A new study led by researchers at the Center for Regenerative Medicine at Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) now describes a safe new potential therapeutic tool for the recovery of liver function in chronic and acute liver diseases.

Kraftige magneter i de nye iPhones kan forhindre ICD-pacemaker i at virke.

A new study led by a University at Buffalo researcher has identified how specific communication among different brain regions, known as brain connectivity, can serve as a biomarker for attention deficit hyperactivity disorder (ADHD).

New research demonstrates that hypnosis–the process of focusing a person's attention on a specific task or sensation–can turn a normally difficult visual task into a far easier one by helping individuals mentally "fill in the gaps" of missing visual cues.

A new paper published Jan. 11 in Nature Sustainability quantifies the tradeoffs between hydroelectric generation capacity and the impacts on river connectivity for thousands of current and projected future dams across Brazil. The findings confirm that small hydropower plants are far more responsible for river fragmentation than their larger counterparts due to their prevalence and distribution.

The widespread use of cashless payments including credit cards, debit cards, and mobile apps has made transactions more convenient for consumers. However, results from previous research have shown that such cashless payments can increase consumers' spending on unhealthy food.

NPR's Ari Shapiro speaks with Judette Louis, president of the Society for Maternal-Fetal Medicine, about the lack of data on how COVID-19 vaccines affect pregnant people.

Early on Wednesday, a vaccine manufacturing facility in the U.K. had to go into lockdown mode after a suspicious package arrived on the site. The pharmaceutical company Wockhardt UK announced that it shut down and evacuated its Wrexham vaccine factory in Wales. The facility had been responsible for bottling the AstraZeneca coronavirus vaccine into glass vials, according to ABC News , making it a

People believe that they can't change their brains, or their brain health will decline as they age. But the SMART training protocol, created by researchers and clinicians at the Center for BrainHealth®, has demonstrated over the past two decades to improve cognitive function and psychological well-being in laboratory participants. Research suggests that SMART can even make long-lasting improvement

The thought of eating insects is stomach turning for many, but new Edith Cowan University (ECU) research is shedding light on allergy causing proteins which could pose serious health risks for those suffering from shellfish allergy. The research, published in the journal Food Chemistry, identified 20 proteins found in cricket food products which could cause serious allergic reactions.

Oil and gas extraction will be paused and wind energy will expand under Joe Biden's climate plan.

Virgin Hyperloop has released a new video showing what the experience of being shot inside a pod down a vacuum tube at breakneck speeds could one day look and feel like. It's an ambitious vision of the future of transportation. The concept video goes through each step in the travel process, from check-in to disembarking. The experience seems reminiscent of going to an airport to catch a plane. Th

The journal Ethology is the first to adopt the guidelines, aimed at clarifying experimental design and the potential biases within.

A new study examined the effects on crime of budget shortfalls in two New Jersey cities–one of which laid off more than 10 percent of its police force while the other averted layoffs. The study found that the police layoffs were associated with significant increases in overall crime, violent crime, and property crime.

Because the chat app doesn't encrypt conversations by default—or at all for group chats—security professionals often warn against it.

Researchers have used neuroimaging to examine how psychotherapy for people with PTSD changes the brain areas responsible for generating emotional responses to threats. Trauma-focused psychotherapy is widely considered the best available treatment for post-traumatic stress disorder (PTSD). However, the ways in which this method affects the brain to promote recovery from PTSD are not well understoo

Small cell lung cancer (SCLC) cells are missing a surface protein that triggers an immune response, allowing them to hide from one of the body's key cancer defenses, a new study suggests. The findings could lead to new treatments for SCLC, which has no effective therapies.

Members of Syracuse University's College of Arts and Sciences are shining new light on an enduring mystery—one that is millions of years in the making.

Before Arsène Lupin was the inspiration for an out-of-nowhere Netflix smash hit, projected to be watched by 70 million subscribers , the character was a French literary legend, a gentleman thief with the moral code of Robin Hood, the wits of Sherlock Holmes, and the anti-aristocratic instincts of Robespierre. In the 1906 story "The Queen's Necklace," one of Maurice Leblanc's first outings for the

Plastic is ubiquitous in people's lives. Yet, when plastic-containing items have fulfilled their missions, only a small amount is recycled into new products, which are often of lower quality compared to the original material. And, transforming this waste into high-value chemicals requires substantial energy. Now, researchers reporting in ACS' JACS Au have combined a ruthenium-carbon catalyst and m

One of President Joe Biden's first post-inauguration acts was to realign the United States with the Paris climate accord, but a new study led by researchers at the University of California, Irvine demonstrates that rising emissions from human land-use will jeopardize the agreement's goals without substantial changes in agricultural practices.

The development of cost-efficient, portable microscopy units would greatly expand their use in remote field locations and in places with fewer resources, potentially leading to easier on-site analysis of contaminants such as E. coli in water sources as well as other practical applications.

In September, a team led by astronomers in the United Kingdom announced that they had detected the chemical phosphine in the thick clouds of Venus. The team's reported detection, based on observations by two Earth-based radio telescopes, surprised many Venus experts. Earth's atmosphere contains small amounts of phosphine, which may be produced by life. Phosphine on Venus generated buzz that the pl

Car accidents are responsible for approximately a million deaths each year globally. Among the many causes, driving at night, when vision is most limited, leads to accidents with higher mortality rates than accidents during the day. Therefore, improving visibility during night driving is critical for reducing the number of fatal car accidents.

A combination of observational data and sophisticated computer simulations have yielded advances in a field of astrophysics that has languished for half a century. The Dark Energy Survey, which is hosted by the U.S. Department of Energy's Fermi National Accelerator Laboratory, has published a burst of new results on what's called intracluster light, or ICL, a faint type of light found inside galax

Studying past Arctic cultures and working with today's northern communities to address present-day socioeconomic and environmental challenges

This freely available technology tool provides a unique learning experience for budding astronomers and artists alike

A wildfire raging in the south of Argentina has consumed a vast swathe of forestland in three days, local authorities said Wednesday—an area half the size of Liechtenstein.

Silicon Valley's problem is not an excess of frat-house behavior. It's much worse.

NASA's OSIRIS-REx mission has been a smashing success so far. After reaching the asteroid Bennu at the very end of 2018, the spacecraft surveyed the surface and collected a sample. Now, NASA is making plans for OSIRIS-REx to head back to Earth with its precious cargo. According to the team, OSIRIS-REx will begin that journey on May 10th , but there are good reasons for the delay. OSIRIS-REx colle

Cells don't express all the genes they contain all the time. The portion of our genome that encodes eye color, for example, doesn't need to be turned on in liver cells. In plants, genes encoding the structure of a flower can be turned off in cells that will form a leaf.

Cells don't express all the genes they contain all the time. The portion of our genome that encodes eye color, for example, doesn't need to be turned on in liver cells. In plants, genes encoding the structure of a flower can be turned off in cells that will form a leaf.

A new 3-D analysis shows that wildland fires flare up in forests populated by similar-sized trees or checkerboarded by large clearings and slow down where trees are more varied. The research can help fire managers better understand the physics and dynamics of fire to improve fire-behavior forecasts.

With the New Year, many people are making resolutions to eat healthier, by eating more vegetables, for example. But those who don't like the taste or texture of some vegetables might prefer to drink them in a home-squeezed juice. Now, researchers reporting in ACS Food Science & Technology have found that the choice of household juicing technique can influence the phytochemical content and antioxid

Don't limit yourself to one position. (Brooke Cagle via Unsplash/) Buying a new laptop or tablet can be a stressful undertaking. With so many brands and models to choose from, how do you pick the one that best meets your needs? Dear indecisive shoppers: You're in luck. If you are in the market for both a new laptop and a new tablet, the best 2-in-1 laptops will give you both in a single device. T

Presidential pup Major Biden stretches his legs on the White House lawn. (White House photo/Adam Schultz/) Ellen Furlong is an associate professor of Psychology at Illinois Wesleyan University. This story originally featured on The Conversation . On January 24 the White House welcomed two new residents: Champ and Major, the newly minted first dogs of the US. The first dogs are poised to offer spe

Researchers found flights between London and New York could have used up to 16% less fuel by more accurately following jet stream tailwinds or avoiding headwinds, at a fraction of the cost of other emissions-cutting technologies.

Scientists conducted the first study to examine the fetal health impact of light pollution based on a direct measure of skyglow, an important aspect of light pollution. Using an empirical regularity discovered in physics, called Walker's Law, a team found evidence of reduced birth weight, shortened gestational length and preterm births.

Harvard researchers have developed a two-millimeter achromatic metalenses that can focus RGB (red, blue, green) colors without aberrations and developed a miniaturized display for virtual and augmented reality applications.

In the first national study to assess use of e-cigarettes among adults with disabilities, George Mason University's College of Health and Human Services researchers found that e-cigarette use was more than twice as likely among adults with a cognitive disability (12.0%), an independent living disability (11.0%), or two or more disabilities (9.2%), compared to adults without disabilities (4.8%).

A committee of experts, formed by NIST and FEMA under the direction of Congress, has urged officials at all levels of government to support research and policies that could help get the buildings and services society depends on up and running quickly after an earthquake. In a report delivered to Congress, the committee outlines seven recommendations that, if acted upon, may greatly improve the res

Nature, Published online: 25 January 2021; doi:10.1038/d41586-021-00215-8 A cyborg Venus flytrap manipulates objects with the tap of a smartphone screen.

Drifting Apart The Atlantic Ocean is steadily growing wider, and our conventional understanding of plate tectonics can't quite explain why. When scientists from Italy and the U.K. dropped 39 seismometers to the bottom of the Atlantic to better understand seismic activity beneath the crust back in 2016, they expected their findings to be "very boring," Gizmodo reports . Instead, they say they've u

The right combination of surfactant, water and processing can maximize the quality of 2D hexagonal boron nitride for such products as antibacterial films.

The terrible scale of the tragedy cannot be attributed to misfortune. It is a product of negligent government In Soho, central London, stands a replica of a 19th-century public water pump without a handle. The missing part is not a result of vandalism but a tribute to John Snow, the physician who correctly surmised that the pump, supplying contaminated water, was a super-spreading device for chol

ONS survey finds people more likely to have cough compared with old variants, though loss of taste or smell less likely Coronavirus – latest updates See all our coronavirus coverage Coughs, sore throats and fatigue are more common in people who test positive for the new variant of coronavirus, but a loss of taste or smell is less likely, a study has found. The highly transmissible variant of coro

We present a unifying theory to explain cancer recurrence, therapeutic resistance, and lethality. The basis of this theory is the formation of simultaneously polyploid and aneuploid cancer cells, polyaneuploid cancer cells (PACCs), that avoid the toxic effects of systemic therapy by entering a state of cell cycle arrest. The theory…

Neutralizing antibodies (nAbs), in the time of COVID-19, have received much attention in the lay press owing to their association with vaccine protection against severe acute respiratory syndrome coronavirus 2. The attention is well-deserved and the association of nAbs with protection is true for many viruses (1). For HIV, we…

The United Nations Decade of Ocean Science for Sustainable Development (2021–2030, henceforth the Ocean Decade) aims to galvanize the international community to acquire and apply scientific knowledge of the ocean. The Ocean Decade is specifically intended to help achieve the Sustainable Development Goals (SDGs), including its promise to "leave no…

Locked cabinets, a secret frequency, and the curious magnetism of a particle called the muon

President Joe Biden continues to make good on his campaign pledge to accelerate progress on climate change, rapidly working down the list of what he can accomplish on his own in his early days in office. On Wednesday, January 27, he will sign a second set of executive orders and memorandums on climate change that promise to bring about major changes in US energy policies and priorities: directing

Astronomers revisited and comprehensively reinterpreted the radio telescope observations underlying a widely reported 2019 claim that phosphine gas was present in the atmosphere of Venus. In a paper accepted to the Astrophysical Journal, they report that sulfur dioxide, a common gas in the atmosphere of Venus, is likely what was detected instead of phosphine.

Paleontologists use ancient marine faunas to test long-term changes in our warming oceans.

Scientists have calculated the mass range for Dark Matter – and it's tighter than the science world thought.

Climate change mitigation is about more than just CO2. So-called 'short-lived climate-forcing pollutants' such as soot, methane, and tropospheric ozone all have harmful effects. Climate policy should be guided by a clearer understanding of their differentiated impacts.

Promising early results from several studies have encouraged researchers around the world to develop and expand canine programs that may screen people for COVID-19 infection at places like airports, hospitals, or sports venues. While these early experiments appear to demonstrate high levels of accuracy by the sniffer dogs, researchers also caution that peer-review processes and larger-scale studi

uOttawa Professor Benoît Lessard and his team are developing carbon-based technologies which could lead to improved flexible phone displays, make robotic skin more sensitive and allow for wearable electronics that could monitor the physical health of athletes in real-time.

People who are pregnant, breastfeeding or trying to conceive should be offered the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine based on ethical grounds, argue authors of a commentary in CMAJ ( Canadian Medical Association Journal )

A study led by a University of Illinois Chicago researcher uses a new approach to measure precarious, or low-quality, employment in the United States. And, according to those findings, precarious employment has increased 9% between 1988 and 2016. Precarious employment, or P.E., is defined as low-quality employment, which is often characterized by low wages, job insecurity and irregular hours, maki

The hormone acts as a barrier against SARS-CoV-2, blocking the expression of genes that encode proteins in cells serving as viral entry points, according to a study by researchers at the University of São Paulo.

A study has revealed for the first time the ancient origins of one of the world's most important ecosystems by unlocking the mechanism which determined the evolution of its mountains and how they shaped the weather there as well as its flora and fauna.

A study presented today by Dr. Nobuyuki Takahashi of the Center for Cancer Research (CCR), National Cancer Institute (NCI), Bethesda, Md. at the IASLC World Conference on Lung Cancer Singapore demonstrates that small cell lung cancer (SCLC) may have an inherited predisposition and lays the foundation for understanding the interaction between genotype and tobacco exposure in exacerbating SCLC risk

In a recent study, a joint research team led by scientists from Xishuangbanna Tropical Botanical Garden (XTBG) of the Chinese Academy of Sciences, the University of Bristol (UK) and the Open University (UK) has revealed the first direct mechanism explaining how the growth of mountains in Northern Tibet drastically altered climate, vegetation and plant diversity in East Asia.

Larvae of a new malaria mosquito species are abundantly present in water containers in cities in Ethiopia. The mosquito, Anopheles stephensi, is the main malaria mosquito in India but only appeared on the African continent a few years ago. It has now been found in cities and towns in urban settings in Ethiopia, Sudan, and Djibouti. Malaria can become an increasing problem for urban areas in Ethiop

An analysis of long-term menstrual cycle records kept by 22 women for up to 32 years shows that women with cycles lasting longer than 27 days intermittently synchronized with cycles that affect the intensity of moonlight and the moon's gravitational pull. This synchrony was lost as women aged and when they were exposed to artificial light at night. The

Organelles continue to thrive after the cells within which they exist die, a team of University of Bristol scientists have found, overturning previous assumptions that organelles decay too quickly to be fossilised.

A study has revealed for the first time the ancient origins of one of the world's most important ecosystems by unlocking the mechanism which determined the evolution of its mountains and how they shaped the weather there as well as its flora and fauna.

Does the moon affect women's menstrual cycles? This question has been controversial for a long time. A new study by chronobiologists from Würzburg (Germany) now suggest that such an influence does exist. It's complicated, though.

Researchers at Washington University School of Medicine in St. Louis have engineered cartilage cells to release an anti-inflammatory drug in response to stresses such cells undergo when they are compressed during weight bearing and movement.

A new machine learning algorithm based on mammograms can estimate the risk of breast cancer in women more accurately than current risk models, according to a study from Adam Yala and colleagues.

To reduce cases of child neglect, provide economic relief to struggling families, research indicates. A 10% increase in a common benefit for low- to moderate-income working families, the Earned Income Tax Credit, led to a 9% decrease in the annual number of reports of child neglect made to child welfare agencies over a 14-year study period. That's a significant impact, researchers say, and can in

Puerto Rico was identified as suffering the greatest climate impacts over that time period — Read more on ScientificAmerican.com

Spacetime Modification Weapon According to documents obtained by The War Zone , the US Navy performed experiments on far-fetched technologies including a "spacetime modification weapon" which, researchers claimed internally, could revolutionize power and propulsion systems. The mysterious technologies were meant to take advantage of the "Pais effect," patented by American aerospace engineer Salva

Research finds people stay up later and sleep less before full moon, and do the opposite before new moon Folklore has saddled the moon with major responsibilities: moods, spikes in crime and even psychosis are blamed on the Earth's only constant natural satellite. But could the "lunar effect" interfere with sleep? Scientists have long understood that human activity is facilitated by light, be it

The invasiveness and high immune suppression of glioblastoma multiforme (GBM) produce poor survival of afflicted patients. Unfortunately, in the past decades, no therapeutic approach has remarkably improved the survival time of patients with GBM. Our analysis of the TCGA database and brain tumor tissue arrays indicated that CXCL1 and CXCL2 overexpression is closely associated with GBM's aggressiv

Na + /K + -ATPase (NKA) plays important roles in maintaining cellular homeostasis. Conversely, reduced NKA activity has been reported in aging and neurodegenerative diseases. However, little is known about the function of NKA in the pathogenesis of Parkinson's disease (PD). Here, we report that reduction of NKA activity in NKAα1 +/– mice aggravates α-synuclein–induced pathology, including a reduc

Heme is the endogenous ligand for the constitutively repressive REV-ERB nuclear receptors, REV-ERBα (NR1D1) and REV-ERBβ (NR1D2), but how heme regulates REV-ERB activity remains unclear. Cellular studies indicate that heme is required for the REV-ERBs to bind the corepressor NCoR and repress transcription. However, fluorescence-based biochemical assays suggest that heme displaces NCoR; here, we s

Endothelial cell injury leading to microvascular rarefaction is a characteristic feature of chronic kidney disease (CKD). However, the mechanism underlying endothelial cell dropout is poorly defined. Here, we show a central role of the extracellular microenvironment in controlling endothelial cell survival and proliferation in CKD. When cultured on a decellularized kidney tissue scaffold (KTS) fr

The growth of the Tibetan Plateau throughout the past 66 million years has profoundly affected the Asian climate, but how this unparalleled orogenesis might have driven vegetation and plant diversity changes in eastern Asia is poorly understood. We approach this question by integrating modeling results and fossil data. We show that growth of north and northeastern Tibet affects vegetation and, cr

Artificial nucleic acid circuits with precisely controllable dynamic and function have shown great promise in biosensing, but their utility in molecular diagnostics is still restrained by the inability to process genomic DNA directly and moderate sensitivity. To address this limitation, we present a CRISPR-Cas–powered catalytic nucleic acid circuit, namely, CRISPR-Cas–only amplification network (

Ubiquitin protein ligase E3 component N-recognin 7 (UBR7) is the most divergent member of UBR box–containing E3 ubiquitin ligases/recognins that mediate the proteasomal degradation of its substrates through the N-end rule. Here, we used a proteomic approach and found phosphoibosyl pyrophosphate synthetases (PRPSs), the essential enzymes for nucleotide biosynthesis, as strong interacting partners

Antibiotic resistance is now a major threat to human health, and one approach to combating this threat is to develop resistance-resistant antibiotics. Synthetic antimicrobial polymers are generally resistance resistant, having good activity with low resistance rates but usually with low therapeutic indices. Here, we report our solution to this problem by introducing dual-selective mechanisms of a

This paper reports a flexible electronics-based epidermal biomicrofluidics technique for clinical continuous blood glucose monitoring, overcoming the drawback of the present wearables, unreliable measurements. A thermal activation method is proposed to improve the efficiency of transdermal interstitial fluid (ISF) extraction, enabling extraction with a low current density to notably reduce skin i

The physical behavior of anisotropic charged colloids is determined by their material dielectric anisotropy, affecting colloidal self-assembly, biological function, and even out-of-equilibrium behavior. However, little is known about anisotropic electrostatic screening, which underlies all electrostatic effective interactions in such soft or biological materials. In this work, we demonstrate anis

Spatially resolved RNA and protein molecular analyses have revealed unexpected heterogeneity of cells. Metabolic analysis of individual cells complements these single-cell studies. Here, we present a three-dimensional spatially resolved metabolomic profiling framework (3D-SMF) to map out the spatial organization of metabolic fragments and protein signatures in immune cells of human tonsils. In th

Uncapping of actin filaments is essential for driving polymerization and depolymerization dynamics from capping protein–associated filaments; however, the mechanisms of uncapping leading to rapid disassembly are unknown. Here, we elucidated the x-ray crystal structure of the actin/twinfilin/capping protein complex to address the mechanisms of twinfilin uncapping of actin filaments. The twinfilin/

The keratin network of intermediate filaments provides keratinocytes with essential mechanical strength and resilience, but the contribution to mechanosensing remains poorly understood. Here, we investigated the role of the keratin cytoskeleton in the response to altered matrix rigidity. We found that keratinocytes adapted to increasing matrix stiffness by forming a rigid, interconnected network

Transparent wood is considered a promising structural and light management material for energy-efficient engineering applications. However, the solution-based delignification process that is used to fabricate transparent wood generally consumes large amounts of chemicals and energy. Here, we report a method to produce optically transparent wood by modifying the wood's lignin structure using a sol

Many free-living and pathogenic enterobacteria secrete biofilm-promoting cellulose using a multicomponent, envelope-embedded Bcs secretion system under the control of intracellular second messenger c-di-GMP. The molecular understanding of system assembly and cellulose secretion has been largely limited to the crystallographic studies of a distantly homologous BcsAB synthase tandem and a low-resol

Next-generation nano- and quantum devices have increasingly complex 3D structure. As the dimensions of these devices shrink to the nanoscale, their performance is often governed by interface quality or precise chemical or dopant composition. Here, we present the first phase-sensitive extreme ultraviolet imaging reflectometer. It combines the excellent phase stability of coherent high-harmonic sou

Lung adenocarcinomas (LUAD) that radiologically display as subsolid nodules (SSNs) exhibit more indolent biological behavior than solid LUAD. The transcriptomic features and tumor microenvironment (TME) of SSN remain poorly understood. Here, we performed single-cell RNA sequencing analyses of 16 SSN samples, 6 adjacent normal lung tissues (nLung), and 9 primary LUAD with lymph node metastasis (mL

Mechanobiologic signals regulate cellular responses under physiologic and pathologic conditions. Using synthetic biology and tissue engineering, we developed a mechanically responsive bioartificial tissue that responds to mechanical loading to produce a preprogrammed therapeutic biologic drug. By deconstructing the signaling networks induced by activation of the mechanically sensitive ion channel

Paramyxovirus membrane fusion requires an attachment protein that binds to a host cell receptor and a fusion protein that merges the viral and host membranes. For Nipah virus (NiV), the G attachment protein binds ephrinB2/B3 receptors and activates F-mediated fusion. To visualize dynamic events of these proteins at the membrane interface, we reconstituted NiV fusion activation by overlaying F- an

Many species synchronize reproductive behavior with a particular phase of the lunar cycle to increase reproductive success. In humans, a lunar influence on reproductive behavior remains controversial, although the human menstrual cycle has a period close to that of the lunar cycle. Here, we analyzed long-term menstrual recordings of individual women with distinct methods for biological rhythm ana

Cancer stem cells (CSCs) are involved in tumorigenesis, recurrence, and therapy resistance. To identify critical regulators of sarcoma CSCs, we performed a reporter-based genome-wide CRISPR-Cas9 screen and uncovered Kruppel-like factor 11 (KLF11) as top candidate. In vitro and in vivo functional annotation defined a negative role of KLF11 in CSCs. Mechanistically, KLF11 and YAP/TEAD bound to adja

Virtual and augmented realities are rapidly developing technologies, but their large-scale penetration will require lightweight optical components with small aberrations. We demonstrate millimeter-scale diameter, high-NA, submicron-thin, metasurface-based lenses that achieve diffraction-limited achromatic focusing of the primary colors by exploiting constructive interference of light from multipl

Chronic activation and dysregulation of the neuroendocrine stress response have severe physiological and psychological consequences, including the development of metabolic and stress-related psychiatric disorders. We provide the first unbiased, cell type–specific, molecular characterization of all three components of the hypothalamic-pituitary-adrenal axis, under baseline and chronic stress condi

Neurotensin receptor 1 (NTSR1) and related G protein–coupled receptors of the ghrelin family are clinically unexploited, and several mechanistic aspects of their activation and inactivation have remained unclear. Enabled by a new crystallization design, we present five new structures: apo-state NTSR1 as well as complexes with nonpeptide inverse agonists SR48692 and SR142948A, partial agonist RTI-

The timing of origin of eukaryotes and the sequence of eukaryogenesis are poorly constrained because their fossil record is difficult to interpret. Claims of fossilized organelles have been discounted on the unsubstantiated perception that they decay too quickly for fossilization. We experimentally characterized the pattern and time scale of decay of nuclei, chloroplasts, and pyrenoids in red and

Biologists believe they are one step closer to a long-held goal of making a cheap, widely available plant a source for energy and fuel, meaning one of the next big weapons in the battle against climate change may be able to trace its roots to the side of a Texas highway.

By parsing data on weather, deer populations and deer-vehicle collisions in Wisconsin, investigators show spatial synchrony could be driving population cycles, rather than the reverse.

Reaching zero net emissions of carbon dioxide from energy and industry by 2050 can be accomplished by rebuilding U.S. energy infrastructure to run primarily on renewable energy, at a net cost of about $1 per person per day, according to new research.

Storskalig trädplantering för att motverka klimatkrisen är inte problemfri. Restaurera förstörd skog i stället för att skapa nya planteringar. Skydda befintlig skog och lyft lokalbefolkningens roll. Det menar forskare som granskat olika försök att återställa skövlad regnskog. – Skogar är avgörande för livet på jorden, 75 procent av planetens växter och djurarter har sitt hem där. Skogarna ger oss

A new University of California, Irvine-led study finds a new method for identifying biomarkers may aid in early cancer diagnosis. The study focused on lung cancer, however the Cell Heterogeneity-Adjusted cLonal Methylation (CHALM) method has been tested on aging and Alzheimer's diseases as well and is expected to be effective for studying other diseases.

Syracuse University paleontologists use ancient marine faunas to test long-term changes in our warming oceans.

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified how breast cancer cells hide from immune cells to stay alive. The discovery could lead to better immunotherapy treatment for patients.

A new study led by scientists at La Jolla Institute for Immunology (LJI) suggests that T cells try to fight SARS-CoV-2 by targeting a broad range of sites on the virus–beyond the key sites on the virus's spike protein. By attacking the virus from many angles, the body has the tools to potentially recognize different SARS-CoV-2 variants.

As surgeons balance the need to control their patients' post-surgery pain with the risk that a routine operation could become the gateway to long-term opioid use or addiction, a new study shows the power of an approach that takes a middle way.

Araceli Biosciences, a provider of advanced biological imaging platforms, today announced the launch of its flagship product, the Araceli EndeavorTM. Endeavor revolutionizes drug discovery by delivering high speed, high resolution, full well scanning of cell-based assays.

For centuries, humans have blamed the moon for our moods, accidents and even natural disasters. But new research indicates that our planet's celestial companion impacts something else entirely—our sleep.

A study has revealed for the first time the ancient origins of one of the world's most important ecosystems by unlocking the mechanism which determined the evolution of its mountains and how they shaped the weather there as well as its flora and fauna.

Organelles continue to thrive after the cells within which they exist die, a team of University of Bristol scientists have found, overturning previous assumptions that organelles decay too quickly to be fossilized.

For centuries, humans have blamed the moon for our moods, accidents and even natural disasters. But new research indicates that our planet's celestial companion impacts something else entirely—our sleep.

A study has revealed for the first time the ancient origins of one of the world's most important ecosystems by unlocking the mechanism which determined the evolution of its mountains and how they shaped the weather there as well as its flora and fauna.

Organelles continue to thrive after the cells within which they exist die, a team of University of Bristol scientists have found, overturning previous assumptions that organelles decay too quickly to be fossilized.

During the pandemic, thousands of women have skipped scans and check-ups. So physicians tapped an algorithm to predict those at the highest risk.

With online scams, data theft, and censorship on the rise, virtual private networks (VPNs) have practically become essential tools for safely browsing the Internet. While the benefits of VPN are numerous, the main purpose is to encrypt your data and help you stay anonymous online, protecting you from would-be hackers, intrusive marketers, and even your own Internet Service Provider (ISP). Though

[no content]

Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global leader in life science research and clinical diagnostic products, today announced the launch of the Bio-Rad Western Blotting Learning Center, an online library that provides comprehensive resources, information, and guidance to help researchers improve their experimental western blotting (or immunoblotting) approaches to obtain high-quality

Sage panel member says PM's claim of doing everything to minimise deaths "so transparently untrue" Coronavirus – latest updates See all our coronavirus coverage Bereaved families, government scientific advisers and public health experts have attacked Boris Johnson's claim that ministers "did everything [they] could … to minimise loss of life and to minimise suffering" during the coronavirus eme

Y ou couldn't have blamed Anthony Fauci if at any point over the past year he'd told Donald Trump he'd had enough, thank you , and quit. Everyone has a breaking point. There was the time the former president called him "a disaster" on a call with Trump-campaign staff. Or the day a White House official gave reporters an oppo-research-style memo claiming that Fauci had been "wrong on things" relate

Technology Allows Faster Creation of Knock-In Cell Lines with Multiple Genes Inserted

It is not too early to learn lessons from Britain's 100,000 death toll

Faint light from rogue stars not bound to galaxies has been something of a mystery to scientists. The dimness of this intracluster light makes it difficult to measure, and no one knows how much there is. Scientists on the Dark Energy Survey, led by Fermilab, have made the most radially extended measurement of this light ever, and they've found that its distribution might point to the distribution

In a recent study published in the Journal of Optical Microsystems, researchers from Japan have come up with an alternative to conventional adaptive driving beam systems: a microelectromechanical systems (MEMS) optical scanner that relies on the piezoelectric effect of electrically induced mechanical vibrations.

A University of Washington-led team has revisited and comprehensively reinterpreted the radio telescope observations underlying a widely reported 2019 claim that phosphine gas was present in the atmosphere of Venus. In a paper accepted to the Astrophysical Journal, they report that sulfur dioxide, a common gas in the atmosphere of Venus, is likely what was detected instead of phosphine.

One potential approach to developing a low-cost portable microscopy system is to use transparent microspheres in combination with affordable low-magnification objective lenses to increase image resolution and sensitivity.

In Nature, a team led by researchers at the University of Texas at Austin, the HudsonAlpha Institute for Biotechnology, and the DOE Joint Genome Institute has produced a high-quality reference sequence of the complex switchgrass genome. Building off this work, researchers at DOE Bioenergy Research Centers are exploring targeted genome editing techniques to customize the crop.

UC Irvine Earth system science researchers conducted an analysis of greenhouse gas emissions from agriculture and land use since 1961, finding some opportunities for mitigation as well as areas where curtailment will require sacrifices.

To start the process of unpacking tightly bundled genetic material, plants depend on the LEAFY pioneer protein, according to work led by University of Pennsylvania biologist Doris Wagner.

Mount Sinai researchers have published one of the first studies using a machine learning technique called "federated learning" to examine electronic health records to better predict how COVID-19 patients will progress.

A new study from Tel Aviv University (TAU) shows, for the first time, how an abnormal number of chromosomes (aneuploidy) — a unique characteristic of cancer cells that researchers have known about for decades — could become a weak point for these cells. The study could lead to the development of future drugs that will use this vulnerability to eliminate the cancer cells.

Plastic is ubiquitous in people's lives. Yet, when plastic-containing items have fulfilled their missions, only a small amount is recycled into new products, which are often of lower quality compared to the original material. And, transforming this waste into high-value chemicals requires substantial energy. Now, researchers reporting in ACS' JACS Au have combined a ruthenium-carbon catalyst and m

Lasers are great for measuring—if they can get a clear view of their target. In biomedical applications, there's often disordered stuff in the way of objects needing measurement. A new technique leverages that disorder to formulate a custom-made, optimal laser light beam. Lasers can make amazingly precise measurements. Invaluable for precision construction and manufacturing, they also allow biome

I Sverige screenas alla kvinnor mellan 40 och 74 år för bröstcancer med mammografi ungefär vartannat år. För de som deltar upptäcks i dag 70 procent av bröstcancerfallen vid screening, medan resten hittas i mellantiden – så kallad "intervallcancer". Dessa är ofta allvarliga, då de utvecklats snabbt. Nu hoppas Fredrik Strand, forskare vid institutionen för onkologi-patologi på Karolinska Institutet

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00256-z Scientists welcome the US's science-based plan, but see a tough road ahead. Plus, reminisce with Operation Warp Speed's Moncef Slaoui and consider a different perspective on satellite images.

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00240-7 Global-health researcher Joshua Vogel describes challenges in maternal and newborn health and how to translate research into practice.

Nature, Published online: 26 January 2021; doi:10.1038/d41586-021-00244-3 Germany's Christian Drosten on everything from new virus variants to staying off Twitter. Plus, Nature Electronics's 2021 technology of the year and an ambitious project to map cancer vulnerabilities.

Smoke from wildfires has more of a cooling effect on the climate system that most models have assumed, a new study of biomass-burning aerosols shows. When wildfires burn forests and grasslands, biomass-burning aerosols are produced, forming smoke clouds. The composition, size, and mixing state of biomass-burning aerosols determine the optical properties of the smoke plumes in the atmosphere, and

Crash Deployment If we want any chance of meeting the ambitious climate goals laid out by the 2015 Paris Agreement, it's becoming increasingly clear that we'll need to find a way to actually reverse past emissions. That's why a team of scientists from the University of California San Diego and Texas A&M University published a call to arms, Wired reports , saying that a "wartime-like crash deploym

"Birds at Home," 2006 (Julie Blackmon) When you think of messiness, you might think of the unsavory ways it manifests: sweaty socks left on the floor, food-encrusted dishes piled in the sink, crumbs on the counter. Messes themselves are easy to identify, but the patterns of behavior that produce them are a bit more nuanced. Really, messiness has two ingredients: making messes, and then not cleani

Editor's Note: Every Wednesday, James Hamblin takes questions from readers about health-related curiosities, concerns, and obsessions. Have one? Email him at paging.dr.hamblin@theatlantic.com . Dear Dr. Hamblin, I'm a 65-year-old art teacher who has non-Hodgkin's lymphoma and rheumatoid arthritis. My small town in Georgia issued a mask mandate, but it was overruled by the governor, so I'm still a

Britain remains outlier but six-week gap for mRNA jab gains international support

For at least a century, ecologists have wondered at the tendency for populations of different species to cycle up and down in steady, rhythmic patterns.

The "Doomsday Clock" illustrating the perils facing the planet and mankind will remain at 100 seconds to midnight this year amid the threats of the coronavirus pandemic, nuclear war and climate change.

For at least a century, ecologists have wondered at the tendency for populations of different species to cycle up and down in steady, rhythmic patterns.

A team of physicists and computer scientists from the U.S. Department of Energy's (DOE) Argonne National Laboratory performed one of the five largest cosmological simulations ever. Data from the simulation will inform sky maps to aid leading large-scale cosmological experiments.

Researchers from the Okinawa Institute of Science and Technology Graduate University (OIST) have created perovskite solar modules with improved stability and efficiency by using a new fabrication technique that reduced defects. Their findings were published on the 25th January in Advanced Energy Materials.

Investigators leading the Lung Cancer Master Protocol, or Lung-MAP trial, will present findings from three translational medicine studies at the 2020 World Conference on Lung Cancer, to be held online January 28-31, 2021.

With the New Year, many people are making resolutions to eat healthier, by eating more vegetables, for example. But those who don't like the taste or texture of some vegetables might prefer to drink them in a home-squeezed juice. Now, researchers reporting in ACS Food Science & Technology have found that the choice of household juicing technique can influence the phytochemical content and antioxid

Imagine a 7-year-old and a college student both take a break from their virtual classes to get a drink of water. When they return, the 7-year-old has difficulty restarting the assignment, while the college student resumes working as if the break never occurred. Nelson Cowan, an expert in working memory at the University of Missouri, believes understanding this developmental age difference can help

A new 3D analysis shows that wildland fires flare up in forests populated by similar-sized trees or checkerboarded by large clearings and slow down where trees are more varied.

In 2016, a team led by UCLA's Martin Monti reported that a 25-year-old man recovering from a coma had made remarkable progress following a treatment to jump-start his brain using ultrasound. Now, Monti and colleagues report that two more patients with severe brain injuries have also made impressive progress thanks to the same technique.

Photographer and scientist Nathan Myhrvold has developed a camera that captures snowflakes at a microscopic level never seen before

A mistaken belief that antibiotics are beneficial for a broad array of conditions leads to their overuse, researchers report. The new study also finds that overuse occurs because doctors are willing to prescribe them when patients ask for medications. Researchers looked at more than 200 peer-reviewed studies to examine the causes behind antibiotic overuse, which can lead to harmful bacteria becom

TOI-178 features six planets circling their host star in a tightly choreographed dance, which makes their disorderly arrangement all the more mysterious. (ESO/L. Calçada/spaceengine.org/) Two hundred light years away sits a planetary system unlike any other yet discovered. It contains at least six worlds, five of which are locked together in a particular type of gravitational tango. More bizarrel

An upsurge of matter from deep beneath the Earth's crust could be pushing the continents of North and South America further apart from Europe and Africa, new research has found.

Half-Heusler Ni-based alloys are thermoelectric materials with the potential for converting waste heat into electricity. However, the origin of their impressive conversion efficiency is not entirely clear. In a recent study, scientists from have attempted to uncover the role that Ni defects have in the crystal structure of these alloys and how their desirable thermoelectric properties are a conseq

When entrepreneurs dream up ideas for new businesses, cannabis use might help, and hinder, their creativity, according to a new study.

A new study co-authored by MIT scholars finds that fact-checking labels, when attached to online news headlines, actually work better after people read false headlines, not when the labels precede the headline or accompany it.

Barn från redan utsatta miljöer har större risk att drabbas av pandemin. Den ökande skolfrånvaron medför stora långsiktiga samhällskostnader, och unga kan få det svårt på arbetsmarknaden under långt tid. Det visar forskning från IFAU om hur pandemin kan drabba barn och unga på sikt. Rapporten från Institutet för arbetsmarknads- och utbildningspolitisk utvärdering (IFAU) baseras på tidigare forskn

With cities around the globe locking down yet again amid soaring COVID-19 numbers, could seasonality be partially to blame? New research from the University of Illinois says yes. In a paper published in Evolutionary Bioinformatics, Illinois researchers show COVID-19 cases and mortality rates, among other epidemiological metrics, are significantly correlated with temperature and latitude across 221

Brigham's Thomas Kupper, MD, and co-authors present results from preclinical studies suggesting skin scarification may help generate lung T cells and provide protection against infectious diseases, with implications for prevention of COVID-19.

Canadian and Swiss researchers have created the first platform to understand the mechanisms underlying blood pressure instability after spinal cord injury. The discovery has led to a new cutting-edge solution. Spinal cord stimulators can bridge the body's autonomous regulation system, controlling blood pressure without medication. Findings are published in Nature.

Genetic variations associated with both increases and reductions in risk of the neurodegenerative disease alter the action of ion channels within cellular organelles called lysosomes, a new Penn study finds.

A global operation has taken down the notorious botnet in a blow to cybercriminals worldwide.

In a new article published in the scientific journal Communications Chemistry, a research group at Uppsala University show, using computer simulations, that ions do not always behave as expected. In their research on molten salts, they were able to see that, in some cases, the ions in the salt mixture they were studying affect one another so much that they may even move in the "wrong" direction—th

Historically redlined neighborhoods are more likely to have a paucity of greenspace today compared to other neighborhoods. The study by researchers at Columbia University Mailman School of Public Health and the University of California, Berkeley and San Francisco, demonstrates the lasting effects of redlining, a racist mortgage appraisal practice of the 1930s that established and exacerbated racia

Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities. However, an innovative breakthrough developed by researchers at Virginia Commonwealth University Massey Cancer Center and the VCU Department of Physics promises to diag

Scientists used a supercomputer to perform one of the five largest cosmological simulations ever — the Last Journey. This simulation will provide crucial data for sky maps to aid leading cosmological experiments.

A newly discovered circuit helps fish to prioritize.

Unlike their simple counterparts in artificial intelligence (AI) applications, neurons in the brain use dendrites – their intricate tree-like branches – to find relevant chunks of information. Now, neuroscientists from the University of Bern have discovered a new computational method to make complex dendrite models much simpler. These faithful reductions may lead AI applications to process informa

People who take opioid medications for chronic pain may have a hard time finding a new primary care clinic that will take them as a patient if they need one, according to a new 'secret shopper' study of hundreds of clinics across the country. Stigma against long-term users of prescription opioids, likely related to the prospect of taking on a patient who might have an opioid use disorder or addict

The Asia Pacific Consortium on Osteoporosis (APCO) has today launched the first pan-Asia Pacific clinical practice standards for the screening, diagnosis, and management of osteoporosis, targeting a broad range of high-risk groups. Published in Osteoporosis International, 'The APCO Framework' comprises 16 minimum clinical standards set to serve as a benchmark for the provision of optimal osteoporo

Researchers from Boston University School of Medicine (BUSM) have identified proteins that are essential for the viability of whole genome doubled tumor cells, yet non-essential to normal cells that comprise the majority of human tissue.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-020-03127-1 The genome of the biofuel crop switchgrass (Panicum virgatum) reveals climate–gene–biomass associations that underlie adaptation in nature and will facilitate improvements of the yield of this crop for bioenergy production.

Scientists demonstrated by experiment that a clean electrolyte/electrode interface is key to realizing high-capacity solid-state lithium batteries. Their findings could pave the way for improved battery designs with increased capacity, stability, and safety for both mobile devices and electric vehicles.

Addiction, or substance use disorder (SUD), is a complex neurological condition that includes drug-seeking behavior among other cognitive, emotional and behavioral features. Synaptic plasticity, or changes in the way neurons communicate with one another, drives these addictive behaviors. A new study now shows that players in the extracellular environment – not just at neuronal interfaces – contrib

A scientist has made a major breakthrough in the understanding of coral bleaching — a process that causes corals to lose their color and eventually leads to their death. The process is triggered by warmer ocean temperatures, and, according to the study, it begins much earlier than previously thought. The bleaching apparently results from a disturbance in the metabolic equilibrium between corals a

Researchers report that intermittent fasting reduced breast cancer risk in obese mice.

Beyond the Grave Aaron Ansuini, a student at Concordia University in Montreal, Canada made a shocking discovery: He found that his art history professor wasn't alive anymore. "HI EXCUSE ME," Ansuini wrote in a tweet , "I just found out the the prof for this online course I'm taking *died in 2019* and he's technically still giving classes since he's *literally my prof for this course* and I'm lear

Climate change mitigation is about more than just CO2. So-called 'short-lived climate-forcing pollutants' such as soot, methane, and tropospheric ozone all have harmful effects. Climate policy should be guided by a clearer understanding of their differentiated impacts.

The latest research into the fans of rival football teams indicates what I've long suspected – adversity has a surprisingly powerful bonding effect I once wrote a book that sought to explore exactly what goes on between the ears of football fans. It was called We Don't Know What We're Doing and will now cost you anything up to 5op to buy. I spoke to fellow West Brom fans who had never missed a ga

By parsing data on weather, deer populations and deer-vehicle collisions in Wisconsin, investigators at the University of Kansas show spatial synchrony could be driving population cycles, rather than the reverse.

Historically redlined neighborhoods are more likely to have a paucity of greenspace today compared to other neighborhoods. The study by researchers at Columbia University Mailman School of Public Health and the University of California, Berkeley and San Francisco, demonstrates the lasting effects of redlining, a racist mortgage appraisal practice of the 1930s that established and exacerbated racia

Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities. However, an innovative breakthrough developed by researchers at Virginia Commonwealth University Massey Cancer Center and the VCU Department of Physics promises to diag

A new report by global poverty nonprofit OxFam finds inequality has increased in every country in the world. The alarming trend is made worse by the coronavirus pandemic, which strained most systems and governments. The gap in wealth, race and gender treatment will increase until governments step in with changes. The coronavirus has not only brought suffering and death to millions of people aroun

When it comes to new innovations to combat the coronavirus pandemic, vaccines have certainly stolen the spotlight away from tests. But that doesn't mean that there aren't new-and-improved ways to test for COVID-19 rolling out. Just take health authorities in Beijing, China, who have started to use anal swabs to probe for signs of the coronavirus, according to Gizmodo . The Chinese government seem

RNAi-based biocontrol is a great alternative to hazardous pesticides and can contribute towards reversing the alarming decline in farmland birds and beneficial insects (especially pollinating ones).

RNAi-based biocontrol is a great alternative to hazardous pesticides and can contribute towards reversing the alarming decline in farmland birds and beneficial insects (especially pollinating ones).

The government faces legal action over its decision to allow the use of a pesticide that harms bees.

A few months ago, when millions of Americans were watching the Netflix series Emily in Paris because it was what we had been given that week, I cued up the first episode and was beset almost immediately by an intense longing. Not for travel, or for opportunities to wear beautiful clothes—two commonly cited high points in an otherwise charmless show—but for sports. Specifically, watching sports in

When marine biologist Stuart Sandin talks about sharks, it sounds like he's describing Jedis of the ocean. "They are terrific predators, fast swimmers and they have amazing senses—they can detect any disturbance in the ocean from great distance," such as smells or tiny changes in water currents.

Sport has benefits for education as well as for health and wellbeing. Being active can help with concentration, and improve grades.

When marine biologist Stuart Sandin talks about sharks, it sounds like he's describing Jedis of the ocean. "They are terrific predators, fast swimmers and they have amazing senses—they can detect any disturbance in the ocean from great distance," such as smells or tiny changes in water currents.

Afsmeltningen går 60 procent hurtigere i dag end for bare 25 år siden.

Do you take walks on public trails? What happens when you encounter some trash?

In order to produce tiny electronic memories or sensors in the future, it is essential to be able to arrange individual metal atoms on an insulating layer. Scientists at Bielefeld University's Faculty of Chemistry have now demonstrated that this is possible at room temperature: molecules of the metal-containing compound molybdenum acetate form an ordered structure on the insulator calcite without

Environmentally friendly energy-conversion technologies, such as fuel cells and water-splitting systems, have attracted considerable attention. However, application of these electrochemical devices is hindered due to the high energy barrier of oxygen reduction reaction (ORR) and hydrogen evolution reaction (HER).

Two-dimensional, layered materials hold great promise for a number of applications, such as alternative platforms for the next-generation of logic and memory devices and flexible energy storage devices. There's still much, however, that remains unknown about them.

A compound that extends lifespan in a tiny nematode worm slows bone loss in aging mice. That surprising result comes from a longitudinal and functional study of 700 aging mice, a project that provides a treasure trove of data for researchers aiming to develop therapeutics to slow aging and age-related diseases.

Researchers at the Francis Crick Institute, the UCL Cancer Institute, and the Cancer Research UK Lung Cancer Centre of Excellence have identified genetic changes in tumours which could be used to predict if immunotherapy drugs would be effective in individual patients.

In a new article published in the scientific journal Communications Chemistry, a research group at Uppsala University show, using computer simulations, that ions do not always behave as expected. In their research on molten salts, they were able to see that, in some cases, the ions in the salt mixture they were studying affect one another so much that they may even move in the "wrong" direction –

Climate change mitigation is about more than just CO2. So-called 'short-lived climate-forcing pollutants' such as soot, methane, and tropospheric ozone all have harmful effects. Climate policy should be guided by a clearer understanding of their differentiated impacts.

The Defiant X employs two coaxial rotors up top, with a propeller in the back to help it accelerate and decelerate. (Sikorsky/Boeing/) The Defiant X is a sleek, futuristic helicopter that's designed to go fast and far. While it doesn't exist as a production aircraft, it's one of two candidates that could be the new Black-Hawk-type helicopter for the U.S. Army. This machine, which is made by Sikor

Whether you're looking for sleep trackers, a traditional wearable, or heart rate monitors, look no further. (Cameron Venti via Unsplash/) The very first fitness trackers were rudimentary step-counters, but technology has advanced since then. Now, whether you want to hit that 10,000 daily step goal, monitor your sleep, or train in a specific heart rate zone, there's a wrist-mounted wearable for yo

Consumers regularly choose books, music, travel destinations and other activities based on recommendations by many people on e-commerce or social media platforms.

Linking molecular components through amide bonds is one of the most important reactions in research and the chemical industry. In the journal Angewandte Chemie, scientists have now introduced a new type of reaction for making amide bonds. Called an ASHA ligation, this reaction is fast, efficient, works under mild aqueous conditions, and is broadly applicable.

Svampar besitter individuella karaktärsdrag, och deras hyfer (enskilda svamptrådar i jorden) beter sig på olika sätt när de utforskar och tar sig fram genom jordens mikroskopiska labyrinter. I jakt på föda. Det är forskare vid Uppsala universitet som undersökt hyfers beteende hos olika svamparter. Studierna är gjorda i laboratorium och de underjordiska gångarna har tillverkats syntetiskt av silik

Despite the fact that the coronavirus pandemic has killed nearly 420,000 people in the United States, Americans are still shockingly reluctant to actually get the vaccine once it becomes available to them. But the number that are willing is slowly growing. The Kaiser Family Foundation's COVID-19 Vaccine Monitor released new poll findings on Wednesday that show an overall decline in vaccine hesita

Back in March, my colleagues at the Frederick S. Pardee Center for the Study of the Longer-Range Future at Boston University thought that it might be useful to begin thinking about "the day after coronavirus." For a research center dedicated to longer-term thinking, it made sense to ask what our post-COVID-19 world might look like. In the months that followed, I learned many things. Most importan

In the moments immediately following the Big Bang, the very first gravitational waves rang out. The product of quantum fluctuations in the new soup of primordial matter, these earliest ripples through the fabric of space-time were quickly amplified by inflationary processes that drove the universe to explosively expand. Primordial gravitational waves, produced nearly 13.8 billion years ago, still

The raging coronavirus pandemic, along with political turbulence and uncertainty, have overwhelmed many of us. From almost the start of 2020, people have been faced with bleak prospects as illness, death , isolation and job losses became unwelcome parts of our reality. Early in the year, many of us watched in horror and despair as insurgents stormed the U.S. Capitol . Indeed, all through these ti

Movements like #MeToo have drawn increased attention to the systemic discrimination facing women in a range of professional fields, from Hollywood and journalism to banking and government. Discrimination is also a problem on user-driven sites like Wikipedia. Wikipedia's 20th birthday is on Jan. 15, 2021 and today it is the thirteenth most popular website worldwide . In December 2020, the online e

USA skal holde sig uden for en aftale om forbud mod fuldt autonome våbensystemer. Kun affyring af atomvåben bør kræve menneskelig indblanding, konkluderer et panel udpeget af den amerikanske regering trods modstand fra flere lande og organisationer.

Astma är tre gånger vanligare bland elitskidåkare än hos svensken i gemen. I den unika klimatkammaren vid Mittuniversitet i Östersund, undersöker Helen Hanstock hur kyla påverkar kroppen vid träning. Målet är att förebygga luftvägssjukdomar.

Culture, civic-mindedness and privacy concerns influence how willing people are to share personal location information to help stem the transmission of COVID-19 in their communities, a new study finds. Such sharing includes giving public health authorities access to their geographic information via data gathered from phone calls, mobile apps, credit card purchases, wristband trackers or other tech

Infecting the nasal passages of mice with the virus that causes COVID-19 led to a rapid, escalating attack on the brain that triggered severe illness, researchers report. The attack happened even after the lungs were successfully clearing themselves of the virus. The findings have implications for understanding the wide range in symptoms and severity of illness among humans who are infected by SA

Nature, Published online: 27 January 2021; doi:10.1038/s41586-021-03258-z

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00247-0 New fossil suggests mammals evolved earlier than previously thought

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00221-w Study of thousands of US-based researchers finds those from sexual and gender minorities are more likely to experience workplace prejudice and harassment.

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00248-z A neuroprosthetic device restores blood-pressure control after spinal-cord injury, and identifying the neurons that help us understand others' beliefs.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-020-03137-z A fossil of the Middle Jurassic haramiyidan Vilevolodon diplomylos with a well-preserved malleus, incus and ectotympanic sheds light on the evolutionary transition from a dual to a single function for the ossicles in mammals.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-021-03185-z The identification of a lysosomal K+ channel complex—comprising AKT and the pore-forming TMEM175—provides insights into the mechanisms through which variants of the pore-forming protein affect the development of Parkinson's disease.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-021-03211-0 An ultra-high-throughput multiplex protein–DNA binding assay is used to assess binding of 270 human transcription factors to 95,886 noncoding variants in the human genome, providing data to improve prediction of the effects of noncoding variants on transcription factor binding and thereby increase understanding of molecular

Nature, Published online: 27 January 2021; doi:10.1038/s41586-021-03225-8 The insulin inhibitory receptor (inceptor) is identified as a negative regulator of insulin and IGF1 signalling that could be targeted for β-cell regeneration in treatments for diabetes.

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00115-x Scientists have long been baffled by the mismatch of climate simulations of the past 12,000 years with temperature reconstructions from geological records. It now emerges that seasonal biases in the records explain the disparity.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-021-03183-1 The 2S–2P transitions in muonic helium-4 ions are measured using laser spectroscopy and used to obtain an α-particle charge-radius value five times more precise than that from electron scattering.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-020-03126-2 Multiplexed imaging of 3,660 chromosomal loci in individual mouse embryonic stem cells by DNA seqFISH+ with immunofluorescence of 17 chromatin marks and subnuclear structures reveals invariant organization of loci within individual cells, and heterogeneous and long-lived distinct combinatorial chromatin states in cellular s

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00087-y The inability to maintain blood pressure is a debilitating consequence of spinal cord injury. This problem has now been circumvented, by artificially recreating a reflex essential for blood-pressure stability.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-020-03114-6 Aneuploid cancer cell lines show increased dependence on the spindle assembly complex (SAC); initially they are resistant to SAC perturbations, but over time they accumulate chromosomal aberrations that impair their fitness.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-020-03133-3 Cancer cells that have undergone whole-genome doubling are more reliant than their near-diploid counterparts on DNA-replication factors, the spindle-assembly checkpoint and a mitotic kinesin protein, KIF18A.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-020-03180-w An epidural spinal cord stimulation system regulates blood pressure in the acute and chronic phases of spinal cord injury.

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00120-0 The size of the helium nucleus has been determined using exotic helium atoms in which one electron has been replaced with its heavier cousin, a muon. The result sheds light on a decade-old puzzle regarding the proton radius.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-020-03138-y Trends in the rate of region- and sector-specific land-use greenhouse gas emissions in 1961–2017 show an acceleration of about 20% per decade after 2001.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-020-03140-4 X-ray diffraction measurements of solid carbon compressed to pressures of about two terapascals (approximately twenty million atmospheres) find that carbon retains a diamond structure even under these extreme conditions.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-020-03173-9 The global abundance of oceanic sharks and rays has decreased by 71% since 1970 and 24 species are threatened with extinction owing to a concomitant increase in fishing pressure.

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00141-9 Insulin is produced by pancreatic β-cells. The identification of a regulator of insulin signalling in these cells cements the long-standing idea that this pathway has a key role in β-cell biology.

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00064-5 Newly discovered fossil evidence has led to a re-evaluation of one of the fundamental transitions in mammalian evolution: the transformation of bones of the lower jaw into those of the middle ear.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-021-03184-0 Recordings of cells in the human dorsomedial prefrontal cortex identify a population of neurons that encode information about others' beliefs and distinguish them from self-belief-related representations, providing insight into cellular-level processing underlying human theory of mind.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-020-03155-x Reanalysis of Holocene sea surface temperature records affirms the role of retreating ice and rising greenhouse gases in driving a steady increase in global temperatures over the past 12,000 years.

Nature, Published online: 27 January 2021; doi:10.1038/d41586-020-03044-3 For those fortunate enough to have survived a deadly disease, a vital question remains: how long does their hard-earned immunity last? Tracking of antibodies in Ebola survivors reveals a surprising pattern.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-021-03231-w The inflammasome receptor AIM2 acts independently of the inflammasome to reduce autoimmunity and stabilize regulatory T cells.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-020-03139-x Data from ocean bottom seismometers show that the mantle transition zone beneath the equatorial Mid-Atlantic Ridge is thin and warm, which suggests more material transfer than previously thought.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-021-03210-1 Binding of METTL3 to chromatin is enriched over IAP family endogenous retroviral elements in mouse embryonic stem cells, helping to ensure the integrity of heterochromatin at these elements.

Nature, Published online: 27 January 2021; doi:10.1038/s41586-020-03146-y In many survivors of Ebola virus infection, antibody responses show long-term patterns of decline followed by restimulation, possibly owing to recrudescence of persisting virus.

Proud Mommy In a new interview with People magazine , Elon Musk's mother Maye Musk said that she knew the Tesla and SpaceX CEO was destined to do great things from an early age. "Well at three, I knew he was a genius, but you still don't know if he's going to do great things," Maye told People . "Because many geniuses end up in a basement being a genius but not applying it," she said. "So I was s

I'm not proud to say that my first reaction to Olivia Rodrigo's "Drivers License," the ballad that seemed to come out of nowhere to break streaming records in the first month of 2021, was, That's it? Rodrigo, a 17-year-old Disney actor, sings in the quavery, Lorde-derived vocal style that seemed all too faddish a half-decade ago . Her heartbroken lyrics skip the sort of fun wordplay that Taylor S

In experiments at the Paul Scherrer Institute PSI, an international research collaboration has measured the radius of the atomic nucleus of helium five times more precisely than ever before. With the aid of the new value, fundamental physical theories can be tested and natural constants can be determined even more precisely. For their measurements, the researchers needed muons—these particles are

We're definitely not out of the pandemic woods yet, and neither is this blog – so let's talk some more about antibodies today, in the hopes that we're getting closer to the time when I (and all of us) can ignore immunology for a while. But we're not ignoring it today! There's a lot of news, a lot of worry, and a lot of speculation about the variant forms of the coronavirus and what that means for

Reaching zero net emissions of carbon dioxide from energy and industry by 2050 can be accomplished by rebuilding U.S. energy infrastructure to run primarily on renewable energy, at a net cost of about $1 per person per day, according to new research published by Lawrence Berkeley National Laboratory, the University of San Francisco (USF), and the consulting firm Evolved Energy Research.

Researchers at Vanderbilt University Medical Center (VUMC) and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles' heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly head off future pandemics.

Linking molecular components through amide bonds is one of the most important reactions in research and the chemical industry. In the journal Angewandte Chemie, scientists have now introduced a new type of reaction for making amide bonds. Called an ASHA ligation, this reaction is fast, efficient, works under mild aqueous conditions, and is broadly applicable.

Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The blocking of inceptor function leads to an increased sensitisation of the insulin signaling pathway in pancreatic beta cells. This might allow protection and regeneration of beta cells for diabetes remission.

A high proportion of survivors of Ebola experienced a resurgence in antibody levels nearly a year after recovery, a new University of Liverpool study has found. Published today in Nature, the finding hints that hidden reservoirs of virus could exist long after symptoms ease and has implications for monitoring programmes and vaccine strategies.

Biologists believe they are one step closer to a long-held goal of making a cheap, widely available plant a source for energy and fuel, meaning one of the next big weapons in the battle against climate change may be able to trace its roots to the side of a Texas highway. The complex genome analysis of switchgrass is explained in a new paper in Nature.

? For the first time, a study shows how an abnormal number of chromosomes (aneuploidy) – a unique characteristic of cancer cells that researchers have known about for decades – can become a vulnerability of these cells. ? The study could lead, in the future, to the development of drugs that will use this trait to eliminate cancer.

Researchers at Washington University School of Medicine in St. Louis have found that immune cells stationed in the meninges, the tissue that covers the brain and spinal cord, monitor the brain and initiate an immune response if they detect a problem.

New findings on the brain and inner ear cavity of a 400-million-year-old platypus-like fish cast light on the evolution of modern jawed vertebrates, according to a study led by Dr. ZHU Youan and Dr. LU Jing from the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences.

Researchers evaluated the association between the pandemic and clinical research and development by studying the initiation of oncology clinical trials over time.

In this observational study of about 7,300 adults with laboratory-confirmed COVID-19 in a New York health system, a schizophrenia spectrum diagnosis was associated with an increased risk of death after adjusting for demographic and medical risk factors. Mood and anxiety disorders weren't associated with increased risk of mortality.

This study among patients in Italy suggests that despite virological recovery, a sizable proportion of patients with COVID-19 experienced respiratory, functional or psychological conditions months after hospital discharge.

Until now, how neurons represent another individual's belief and thoughts was unknown. Prior to undergoing planned neurosurgery, patients agreed to perform brief behavioral tasks as neuroscientists recorded the activity of individual neurons. The study revealed the basic cellular mechanism involved in a fundamental cognitive process vital to successful social interactions. Now researchers have a f

The inner ear of a 400 million-year-old 'platypus fish' has yielded new insights into early vertebrate evolution, suggesting this ancient creature may be more closely related to modern-day sharks and bony fish than previously thought.

People with schizophrenia, a mental disorder that affects mood and perception of reality, are almost three times more likely to die from the coronavirus than those without the psychiatric illness, a new study shows. Their higher risk, the investigators say, cannot be explained by other factors that often accompany serious mental health disorders, such as higher rates of heart disease, diabetes, an

In experiments at the Paul Scherrer Institute PSI, an international research collaboration has measured the radius of the atomic nucleus of helium five times more precisely than ever before. With the aid of the new value, fundamental physical theories can be tested and natural constants can be determined even more precisely

In a report presented today to Patricia Espinosa, Executive Secretary of the United Nations Framework Convention on Climate Change (UNFCCC), report authors outlined some of 2020's most important findings within the field of climate science, ranging from improved models that reveal the need for aggressive emission cuts in order to meet the Paris Agreement to the growing use of human rights litigati

Scientists have resolved a key climate change mystery, showing that the annual global temperature today is the warmest of the past 10,000 years – contrary to recent research, according to a Rutgers-led study in the journal Nature .

An upsurge of matter from deep beneath the Earth's crust could be pushing the continents of North and South America further apart from Europe and Africa, new research has found.

A research group led by Prof. Hiroyasu Nakano at the Department of Biochemistry, Toho University Faculty of Medicine, identified Mind bomb-2 (MIB2) as an enzyme that ubiquitinates and modifies the protein cFLIP, which plays a central role in suppressing cell death. This finding indicates that ubiquitination of cFLIP by MIB2 plays an essential role in suppressing caspase 8-mediated cell death, sugg

A research group from Kumamoto University (Japan) has developed an automated measurement system to assess healthy lifespans using nematodes (C. elegans). Based on qualitative differences in lifespans, this system can classify populations of nematodes that are, on average, healthy and long-lived, healthy and die prematurely, and living with long periods of poor health. Since there are many similari

Birds play an underrecognized role in spreading tickborne disease due to their capacity for long-distance travel and tendency to split their time in different parts of the world—patterns that are shifting due to climate change. Knowing which bird species are able to infect ticks with pathogens can help scientists predict where tickborne diseases might emerge and pose a health risk to people.

A newly discovered trace fossil of an ancient burrow has been named after University of Alberta paleontologist Murray Gingras. The fossil, discovered by a former graduate student, has an important role to play in gauging how salty ancient bodies of water were, putting together a clearer picture of our planet's past.

With impacts of climate change threatening to be as abrupt and far-reaching in the coming years as the current pandemic, leading scientists have released a compilation of the 10 most important insights on the climate from the last year to help inform collective action on the ongoing climate crisis.

A research group led by Prof. Hiroyasu Nakano at the Department of Biochemistry, Toho University Faculty of Medicine, identified Mind bomb-2 (MIB2) as an enzyme that ubiquitinates and modifies the protein cFLIP, which plays a central role in suppressing cell death. This finding indicates that ubiquitination of cFLIP by MIB2 plays an essential role in suppressing caspase 8-mediated cell death, sugg

A research group from Kumamoto University (Japan) has developed an automated measurement system to assess healthy lifespans using nematodes (C. elegans). Based on qualitative differences in lifespans, this system can classify populations of nematodes that are, on average, healthy and long-lived, healthy and die prematurely, and living with long periods of poor health. Since there are many similari

Birds play an underrecognized role in spreading tickborne disease due to their capacity for long-distance travel and tendency to split their time in different parts of the world—patterns that are shifting due to climate change. Knowing which bird species are able to infect ticks with pathogens can help scientists predict where tickborne diseases might emerge and pose a health risk to people.

Scientists have calculated the mass range for Dark Matter—and it's tighter than the science world thought.

A newly discovered trace fossil of an ancient burrow has been named after University of Alberta paleontologist Murray Gingras. The fossil, discovered by a former graduate student, has an important role to play in gauging how salty ancient bodies of water were, putting together a clearer picture of our planet's past.

Researchers from the Hong Kong University of Science and Technology (HKSUST) and the University of Hong Kong (HKU) recently demonstrated that the selectivity determinant of Origin Recognition Complex (ORC) for DNA binding lies in a 19-amino acid insertion helix in the Orc4 subunit, which is present in yeast but absent in human. Removal of this motif from Orc4 transforms the yeast ORC, which select

Researchers have been observing serious declines in oceanic and coastal shark populations around the Atlantic Ocean and in the waters off of South Africa and Australia for decades. (Pixabay/) Over the past half-century, oceanic sharks and rays have diminished around the globe, an international team of scientists reported on January 27 in the journal Nature . The researchers analyzed records datin

Overfishing has cut oceanic shark populations by 71% over past 50 years, global survey finds

Researchers from the Hong Kong University of Science and Technology (HKSUST) and the University of Hong Kong (HKU) recently demonstrated that the selectivity determinant of Origin Recognition Complex (ORC) for DNA binding lies in a 19-amino acid insertion helix in the Orc4 subunit, which is present in yeast but absent in human. Removal of this motif from Orc4 transforms the yeast ORC, which select

Benthic plastic litter is a main source of pollutants in oceans, but how it disperses is largely unknown. This study by Guangfa Zhong and Xiaotong Peng, published today in Geology, presents novel findings on the distribution patterns and dispersion mechanisms of deep-sea plastic waste in a submarined canyon located in the northwestern South China Sea.

A fifth basic flavor has crept into our conceptualisation of foods in recent years—umami. In Japanese, umami translates roughly to 'savory deliciousness'.

Scientists say sharks and rays are disappearing from the world's oceans at an "alarming" rate.

If vacuum ultraviolet lasers can be focused into a small beam spot, it will allow investigation of mesoscopic materials and structures and enable the manufacture of nano-objects with excellent precision. Towards this goal, Scientist in China invented a 177 nm VUV laser system that can achieve a sub-micron focal spot at a long focal length. This system can be re-equipped for usage in low-cost angle

Although the reputation of Champagne is well established, the history of Champagne wines and vineyards is poorly documented. However, a research team led by scientists from the CNRS and the Université de Montpellier at the Institut des sciences de l'évolution de Montpellier has just lifted the veil on this history by analyzing the archaeological grape seeds from excavations carried out in Troyes a

Scientists say temperatures globally at highest level since start of human civilisation The planet is hotter now than it has been for at least 12,000 years, a period spanning the entire development of human civilisation, according to research. Analysis of ocean surface temperatures shows human-driven climate change has put the world in "uncharted territory", the scientists say. The planet may eve

Healthcare and police chiefs also say online activity is channelling hatred against NHS staff Coronavirus – latest updates See all our coronavirus coverage Lives are being put at risk and the care of patients disrupted by a spate of hospital incursions from Covid-19 deniers whose online activity is channelling hatred against NHS staff, say healthcare and police chiefs. In the latest example of a

A study of people in Sierra Leone suggests that the virus can lie in hiding from the immune system before re-emerging later and sparking a new response—although researchers didn't examine whether this could make people infectious again.

Oceanic sharks and rays have declined more than 70 percent since 1970, mainly because of overfishing, according to a new study.

Biologists believe they are one step closer to a long-held goal of making a cheap, widely available plant a source for energy and fuel, meaning one of the next big weapons in the battle against climate change may be able to trace its roots to the side of a Texas highway.

The inner ear of a 400 million-year-old 'platypus fish' has yielded new insights into early vertebrate evolution, suggesting this ancient creature may be more closely related to modern-day sharks and bony fish than previously thought.

An upsurge of matter from deep beneath the Earth's crust could be pushing the continents of North and South America further apart from Europe and Africa, new research has found.

Scientists have resolved a key climate change mystery, showing that the annual global temperature today is the warmest of the past 10,000 years—contrary to recent research, according to a Rutgers-led study in the journal Nature.

Biologists believe they are one step closer to a long-held goal of making a cheap, widely available plant a source for energy and fuel, meaning one of the next big weapons in the battle against climate change may be able to trace its roots to the side of a Texas highway.

The inner ear of a 400 million-year-old 'platypus fish' has yielded new insights into early vertebrate evolution, suggesting this ancient creature may be more closely related to modern-day sharks and bony fish than previously thought.

The abrupt shift to online learning due to COVID-19 rocked the US education system, unearthing many of the inequities at its foundation. Educator Nora Flanagan says we can reframe this moment as an opportunity to fix what's long been broken for teachers, students and families — and shares four ways schools can reinvent themselves for a post-pandemic world.

Even after accounting for differences in income, education, caregiver support, special education services and parental reports of misbehavior and family conflict, elementary school-age Black children are 3.5 times more likely to be suspended or placed in detention than their white peers, a new study finds.

Although the reputation of Champagne is well established, the history of Champagne wines and vineyards is poorly documented. However, a research team led by scientists from the CNRS and the Université de Montpellier at the Institut des sciences de l'évolution de Montpellier has just lifted the veil on this history by analysing the archaeological grape seeds from excavations carried out in Troyes a

Imagine what it's doing to the continents!

Climate change is a likely culprit, but scientists are still determining the reason for the frozen tundra's cavernous phenomena.

A tree grows strong from years of generating its own food. Now imagine if products could be strengthened with the same living materials that provide nutrients to strengthen trees. This is the work of USC Viterbi School of Engineering Civil and Environmental Engineering Professor Qiming Wang whose research lab is one of the first to infuse 3-D printer ink with living material. The material has pote

Doctors call for extra efforts amid signs black people and those in poor areas are less likely to receive jabs Coronavirus – latest updates See all our coronavirus coverage Doctors have raised concerns about "worrying" disparities in vaccine coverage in England amid signs black people and those in more deprived areas were less likely to receive the vaccine than others in the first weeks of rollou

Health authorities should develop targeted health messages for vaping product and e-liquid packaging to encourage smokers to switch from cigarettes to e-cigarettes and to prevent non-smokers from taking up vaping, a researcher at the University of Otago, Wellington, New Zealand, says.

The first human cases of COVID-19 (subsequently named SARS-Cov-2) were first reported by officials in Wuhan City, China, in December 2019. The first cases of the virus in Europe were discovered at the end of January 2020. Although there were really no preventative measures that could have completely stopped the pandemic, a new study takes a retrospective look at the months preceding the rapid spr

Wildfires are the enemy when they threaten homes in California and elsewhere. But a new study suggests that people living in fire-prone places can learn to manage fire as an ally to prevent dangerous blazes, just like people who lived nearly 1,000 years ago.

Nigeria has seized pangolin scales and tusks and bones from endangered species allegedly bound for export to Vietnam, a senior customs official said Wednesday.

Though they focus on the star at the center of our solar system, three of NASA's Sun-watching spacecraft have captured unique views of the planets throughout the last several months. Using instruments that look not at the Sun itself, but at the constant outflow of solar material from the Sun, the missions—ESA and NASA's Solar Orbiter, NASA's Parker Solar Probe, and NASA's Solar and Terrestrial Rel

Nigeria has seized pangolin scales and tusks and bones from endangered species allegedly bound for export to Vietnam, a senior customs official said Wednesday.

President Joe Biden made a bold commitment on Tuesday, promising that the United States will vaccinate 300 million residents against the coronavirus by the end of summer. It's an extremely ambitious timeline, and there are no guarantees he'll succeed. But if the country pulls it off, Americans will finally have a chance of returning to a semblance of normal life. "To a nation waiting for action,

Scientists have calculated the mass range for Dark Matter – and it's tighter than the science world thought.

As Covid-19 continues to put pressure on healthcare providers around the world, engineers at the University of Bath have published a mathematical model that could help clinicians to safely allow two people to share a single ventilator.

A massive amount of information downloaded from Parler includes potentially incriminating material. But innocuous posts on mainstream platforms can also create vulnerabilities — Read more on ScientificAmerican.com

Almost a decade ago, Feryal Özel and her colleagues noticed something odd. While a variety of possible black holes had been found in our galaxy, none appeared to fall below a certain size. "There seemed to be a dearth of black holes below 5 solar masses," she said. "Statistically, this was very significant." Since Özel, an astrophysicist at the University of Arizona, published a paper on the prob

Spacewalking astronauts installed a high-speed data link outside the International Space Station's European lab on Wednesday and tackled other improvements.

President Joe Biden on Wednesday was undertaking the most ambitious effort ever to cut America's oil, gas and coal emissions and stave off the worst effects of climate change. New executive orders target federal subsidies for those industries and halt new oil and gas leases on federal lands and waters.

Controlling COVID is essential to restoring the economy, Lisa Kahn says In a typical recession in the US economy, most job losses are permanent. Only a small percentage are considered temporary, where a worker can reasonably expect to be called back. "The shutdowns are not what have been driving the economic collapse; it's the global pandemic." But Kahn , a professor of economics at the Universit

A massive amount of information downloaded from Parler includes potentially incriminating material. But innocuous posts on mainstream platforms can also create vulnerabilities — Read more on ScientificAmerican.com

A team of researchers from several institutions in the U.K., one in the U.S. and one in Spain has found that measures to promote social distancing of school children to reduce COVID-19 exposure reduced contacts on average by 50 to 62% in a study of students in British schools. In their paper published in the journal Royal Society Open Science, the group describes conducting interviews with school

A study led by a University of Illinois Chicago researcher uses a new approach to measure precarious, or low-quality, employment in the United States. And, according to those findings, precarious employment has increased 9% between 1988 and 2016.

Varghese Mathai is a physicist at the University of Massachusetts Amherst who studies the flow of fluids and gases. He conducted a study using computational fluid dynamics simulations to understand how air flows inside a car and its implications for COVID-19 airborne transmission. In this interview, he explains the optimal ways to ensure maximum airflow inside a car.

Forty-five senators voted yesterday not to proceed with a second impeachment trial of Donald Trump. That should come as some relief for the ex-president: Twice impeached, he will likely be twice acquitted. But how much relief? The Senate will still hold a trial. The whole country will again view the video of Trump inciting a crowd to attack Congress as he aimed to coerce his own vice president in

The European Data Relay System, or EDRS, uses cutting-edge laser technology to greatly reduce the time it takes for information to be sent from low-Earth orbiting spacecraft—such as the Earth observing Sentinel satellites—to Earth.

A newly discovered trace fossil of an ancient burrow has been discovered. The fossil has an important role to play in gauging how salty ancient bodies of water were, putting together a clearer picture of our planet's past.

The first baby conceived using in-vitro fertilization (IVF) was born in the UK in 1978 . Over 40 years later, the technique has become commonplace, but its success rate is still fairly low at around 22 to 30 percent . A female-founded Israeli startup called Embryonics is setting out to change this by using artificial intelligence to screen embryos. IVF consists of fertilizing a woman's egg with h

Diabetics living in the UK worry about disruption to insulin supplies as a result of Brexit, new research shows.

The study followed 240 pregnant women between March and June 2020 and found that the COVID-19 mortality rate in the pregnant women was significantly higher when compared to the COVID-19 mortality rate in similarly aged individuals within Washington state.

Climate change may challenge organismal responses through not only extreme cues. An uncommon combination of benign cues – warm and short days – can also trigger reactions such as misregulations of leaves.

Researchers from the HKSUST and the HKU recently demonstrated that the selectivity determinant of Origin Recognition Complex for DNA binding lies in a 19-amino acid insertion helix in the Orc4 subunit, which is present in yeast but absent in human.

In a new and first of its kind study, University of Copenhagen researchers study fermented beverages to find the one with the most umami flavour. Which one wins–champagne, beer, wine or sake? A UCPH researcher answers below.

Move highlights EU's mounting problems with coronavirus vaccine rollout

Hvis vi ikke snart finder bedre behandlinger til personer med en række demenssygdomme, kommer presset fra demografien til at slå den økonomiske bund ud af sundhedssystemet. Det forudsiger adm. direktør i Alzheimerforeningen, Nis Peter Nissen.

Scientists are working to find out how to stop the transmission of mutations that started in England, South Africa and Brazil Sharon Peacock is director of the Covid-19 Genomics UK Consortium Coronavirus – latest updates See all our coronavirus coverage The recent announcement that the Covid variant first detected in the south of England could be more deadly than its predecessor was alarming to e

Using CRISPR gene-editing technology, researchers have produced mosquitoes unable to replicate Zika virus and therefore also unable to infect a human through biting. In 2016, the World Health Organization called the Zika virus epidemic a "public health emergency of international concern" due to the virus causing birth defects for pregnant women in addition to neurological problems. Since then, re

Every weekday evening, our editors guide you through the biggest stories of the day, help you discover new ideas, and surprise you with moments of delight. Subscribe to get this delivered to your inbox . After weeks of brutal expansion, the pandemic is finally beginning to let up. The seven-day average of cases is down a third from its mid-January peak. But the U.S. needs to quickly distribute va

Throughout the pandemic, one of the more puzzling aspects of the coronavirus has been the prevalence of new mental or neurological illnesses among COVID-19 patients. Now there's even more evidence linking the two. About one out of every eight coronavirus patients seems to end up getting diagnosed with their first neurological or psychiatric condition within six months, according to new follow-up

Some languages require less neural activity than others. But these are not necessarily the ones we would imagine. In a study published today in the journal PLOS Biology, researchers at the University of Zurich have shown that languages that are often considered 'easy' actually require an enormous amount of work from our brains.

For many of us, as we get older the skin on our face begins to sag and we seem to lose volume around our eyes, cheeks and chin. Is gravity taking its toll in our later years or do we lose fat over the course of several years that many of us associate with youth, vibrancy and energy? Understanding the cause is paramount to how plastic surgeons treat the signs of facial aging.

A study led by Ludwig Chicago Co-director Ralph Weichselbaum and Yang-Xin Fu of the University of Texas Southwestern Medical Center has shown how bacteria in the gut can dull the efficacy of radiotherapy, a treatment received by about half of all cancer patients.

Benthic plastic litter is a main source of pollutants in oceans, but how it disperses is largely unknown. This study by Guangfa Zhong and Xiaotong Peng, published today in Geology, presents novel findings on the distribution patterns and dispersion mechanisms of deep-sea plastic waste in a submarined canyon located in the northwestern South China Sea.

Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN. Their experiments revealed that TALEN is up to five times more efficient than CRISPR-Cas9 in parts of the genome, called heterochromatin, that are densely packed. Fragile X syndrome, sickle cell anemia, beta-thalassemia and other diseases are the result of genetic defects in the heterochromatin.

New research suggests estimates of the species' current distribution are potentially overestimating range size.

A physics professor has joined forces with language experts to build a 'linguistic thermometer' that can record the temperature of 'hot' or 'cold' (ie fast or slow) developments in modern linguistic features to create a computer-based model that can provide a better understanding of the development in human language and innovation stretching back to pre-history.

Heart disease is a killer threat for southern sea otters feasting on domoic acid in their food web. Climate change projections indicate that toxic blooms and domoic acid exposure will continue to rise.

Tune in and tune out. (Nappy.co/) If you're reading this, you're probably stressed. Never fear: We've dug through the evidence to reveal what science really says about finding zen—and holding onto it through tough times. Want to try meditation ? Take better baths ? Stop anxiety in its tracks ? Welcome to Calm Month . It's a habit clipped straight from a 1950s sitcom: Get home from work, have dinn

When we build new apartment block developments, we have to weigh up a number of factors, such as the number of apartments, their layouts, and access to light and a view.

Privacy is among the most cherished of American rights. Yet, one of society's most vulnerable populations—Black children—are denied the benefits of the right to privacy through discriminatory educational practices, and a growing number of Black parents are turning to home education to protect that right, according to a University of Kansas privacy law scholar.

Physicists at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) are figuring out new ways to accelerate electrons to record-high energies over record-short distances with a technique that uses laser pulses and exotic matter known as a plasma. But measuring the properties of the high-energy electron beams produced in laser-plasma acceleration experiments has prove

A chemical probe molecule—a "first gen" molecule that can be used for drug development—that targets a host cell's protein quality control pathways can dramatically reduce infection by Dengue and Zika viruses. The research led by Lars Plate, assistant professor of chemistry and biological sciences, is a significant step toward host-directed antiviral therapeutics that act on host cells and not the

An international team of researchers has used modeling techniques borrowed from chemistry applications to create a new kind of city simulator. In their paper published in the journal Proceedings of the Royal Society A, the group describes using their models to create simulations of of COVID-19 spread for two real-world cities: Birmingham England and Bogota Columbia.

Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN. Their experiments revealed that TALEN is up to five times more efficient than CRISPR-Cas9 in parts of the genome, called heterochromatin, that are densely packed. Fragile X syndrome, sickle cell anemia, beta-thalassemia and other diseases are the result of genetic defects in the heterochromatin.

A research group led by Prof. Hiroyasu Nakano at the Department of Biochemistry, Toho University Faculty of Medicine, identified Mind bomb-2 (MIB2) as an enzyme that ubiquitinates and modifies the protein cFLIP, which plays a central role in suppressing cell death. This finding indicates that ubiquitination of cFLIP by MIB2 plays an essential role in suppressing caspase 8-mediated cell death, sugg

Image that products could be strengthened with the same living materials that provide nutrients to strengthen trees. Professor Qiming Wang's research lab is one of the first to infuse 3-D printer ink with living material. The material has potential for greater strength, to be flexible and self-heal.

Researchers have developed an automated measurement system to assess healthy lifespan using nematodes. This system performs a mini-population analysis to classify specific populations of nematodes based on qualitative differences in lifespan. Since there are many similarities between the mechanisms that determine the lifespan of nematodes and humans, this system could make it easier to develop dru

MEDIA: Trauma-focused psychotherapy is the best-known treatment for PTSD. But how does it work? Dell Med researcher Greg Fonzo says he may have found the answer by exploring how different parts of the brain talk to one another.

The overuse of antibiotics occurs due to the mistaken widespread belief that they are beneficial for a broad array of conditions and because many physicians are willing to prescribe antibiotics if patients ask for the medication, according to a Rutgers study.

If vacuum ultraviolet lasers can be focused into a small beam spot, it will allow investigation of mesoscopic materials and structures and enable the manufacture of nano-objects with excellent precision. Towards this goal, Scientist in China invented a 177 nm VUV laser system that can achieve a sub-micron focal spot at a long focal length. This system can be re-equipped for usage in low-cost ARPES

A new study published in the journal Global Ecology and Biogeography used machine learning to identify bird species with the potential to transmit the Lyme disease bacterium (Borrelia burgdorferi) to feeding ticks. The team developed a model that identified birds known to spread Lyme disease with 80% accuracy and flagged 21 new species that should be prioritized for surveillance.

A newly discovered trace fossil of an ancient burrow has been named after University of Alberta paleontologist Murray Gingras. The fossil, discovered by a former graduate student, has an important role to play in gauging how salty ancient bodies of water were, putting together a clearer picture of our planet's past.

A chemical probe molecule—a "first gen" molecule that can be used for drug development—that targets a host cell's protein quality control pathways can dramatically reduce infection by Dengue and Zika viruses. The research led by Lars Plate, assistant professor of chemistry and biological sciences, is a significant step toward host-directed antiviral therapeutics that act on host cells and not the

3-D printing is a universal process in the sense that pretty much any part that can be drawn up in a CAD program can be printed, at least within a certain resolution. Machining a part on a mill or lathe, while having the advantage of greater accuracy and material options, is a slightly less universal process in that many possible designs that exist in theory could never be machined. A hollow spher

3-D printing is a universal process in the sense that pretty much any part that can be drawn up in a CAD program can be printed, at least within a certain resolution. Machining a part on a mill or lathe, while having the advantage of greater accuracy and material options, is a slightly less universal process in that many possible designs that exist in theory could never be machined. A hollow spher

The chickens have come home to roost for Alberta Premier Jason Kenney. Kenney bet around $1.5 billion of public money on a very risky prospect—the highly controversial Keystone XL pipeline.

Domestic and family violence soars in the months and years following natural disasters. It usually involves physical and psychological violence perpetrated by men against women and children, but it can also include an escalation in sexual, financial and emotional abuse.

This summer's wetter conditions have created great conditions for flowering plants. Flowers provide sweet nectar and protein-rich pollen, attracting many insects, including bees.

For decades, multilevel-marketing companies had it easy. Cutco knives, Tupperware containers, and Pampered Chef bread mixes were inoffensive products sold at weeknight wine parties and, later, in themed Facebook groups. For the most part, they were an unremarkable part of women's lives . Multilevel marketing—a form of direct selling in which a major chunk of a person's income comes not from the s

The array of executive orders elevate climate change at every level of the federal government

This summer's wetter conditions have created great conditions for flowering plants. Flowers provide sweet nectar and protein-rich pollen, attracting many insects, including bees.

This light, versatile, and low-maintenance bicycle has reconciled me to the existence of gravel bikes.

Life is chaos, but needing to control a fictional story can be stressful too.

Educators have lobbied to be prioritized for the Covid-19 vaccine, but they've also made the ethically questionable call to continue to wait to reopen.

The Long Haul: Improving Cardiac Cell Therapy Persistence

When you struggle to sleep in an unfamiliar setting, your brain might be trying to protect you. Researchers call this the First Night Effect.

PLUS. Den tyske motorproducent Deutz og virksomhedens danske forhandler snød i 2010 DSB til at betale overpris for reservedele til IC3-togene. Nu er selskaberne også blevet dømt i Sø- og Handelsretten.

Astronomers report the finding of a new candidate redback millisecond pulsar (MSP) binary associated with a gamma-ray source known as 4FGL J0940.3–7610. The newly found object is a short-period compact binary exhibiting X-ray emission that consists of a low-mass neutron star and a companion star with a mass most likely over 0.4 solar masses. The discovery is detailed in a paper published January 2

Cells need to cooperate to coexist in people, and when some break the rules, cancer results — Read more on ScientificAmerican.com

New research has reignited the debate around the behavior of the giant dinosaur Spinosaurus.

Cells need to cooperate to coexist in people, and when some break the rules, cancer results — Read more on ScientificAmerican.com

President Biden's nominee to lead the Department of Energy would control powerful levers to promote clean-energy technologies, though that's not the agency's only job. Still, here are five possible steps.

Scientists are scrambling to patch the cracks forming in the global marine weather monitoring system

PLUS. En HH forbindelse er en god forretning for samfundet – men det gælder kun den rene vejforbindelse, viser strategisk analyse.

Plants and other organisms can adapt their phenotypes to fluctuating environmental conditions within certain limits. The leaves of the dandelion, for example, are much more small in sunny locations than in shady places. In the sun, less leaf area is adequate to drive sufficient photosynthesis. This makes sense and is part of the dandelion's genetic programming.

"COVID schmovid! What's the worst that could happen, right?" When people are living through dark times, they use humor to lighten the mood, and a particular linguistic quirk has been explored in an article co-authored by a Malmö University senior lecturer.

For the first time, an international team of researchers has visualized the light-sensitive protein archaerhodopsin-3 (AR3) at unprecedented resolution using the I24 and B23 beamlines at Diamond Light Source. The photoreceptor is expressed by Halorubrum sodomense, an organism that grows in the Dead Sea, but is best known for its applications in optogenetics experiments, in which it is used to sile

The Baryon Antibaryon Symmetry Experiment (BASE) at CERN's Antimatter Factory has set new limits on the existence of axion-like particles, and how easily those in a narrow mass range around 2.97 neV could turn into photons, the particles of light. BASE's new result, published by Physical Review Letters, describes this pioneering method and opens up new experimental possibilities in the search for

Plants and other organisms can adapt their phenotypes to fluctuating environmental conditions within certain limits. The leaves of the dandelion, for example, are much more small in sunny locations than in shady places. In the sun, less leaf area is adequate to drive sufficient photosynthesis. This makes sense and is part of the dandelion's genetic programming.

For the first time, an international team of researchers has visualized the light-sensitive protein archaerhodopsin-3 (AR3) at unprecedented resolution using the I24 and B23 beamlines at Diamond Light Source. The photoreceptor is expressed by Halorubrum sodomense, an organism that grows in the Dead Sea, but is best known for its applications in optogenetics experiments, in which it is used to sile

Lack of access to jabs in emerging markets could have global consequences, fund says

How cells develop and the diseases that arise when development goes wrong have been a decades-long research focus in the laboratory of Distinguished Professor of Biology Ellen Rothenberg. In particular, the lab studies the development of immune cells known as T cells, which act as "intelligence agents"—they circulate throughout the body, detect threats, and determine what kind of response the immu

How cells develop and the diseases that arise when development goes wrong have been a decades-long research focus in the laboratory of Distinguished Professor of Biology Ellen Rothenberg. In particular, the lab studies the development of immune cells known as T cells, which act as "intelligence agents"—they circulate throughout the body, detect threats, and determine what kind of response the immu

Widespread use of antibiotics in human healthcare and livestock husbandry has led to trace amounts of the drugs ending up in food products. Long-term consumption could cause health problems, but it's been difficult to analyze more than a few antibiotics at a time because they have different chemical properties. Now, researchers reporting in ACS' Journal of Agricultural and Food Chemistry have deve

Scientists have leveraged big data from recruitment platforms and machine learning to study hiring discrimination. They find that discrimination against immigrants depends, among other things, on the time of day, and that both men and women face discrimination. This type of discrimination violates the principle of equal opportunities. For those affected, this may have long-term disadvantages, suc

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00231-8 A taste of freedom.

There are more than one genetic engineering technologies available. Here's a comparison. The post first appeared on Science-Based Medicine .

Widespread use of antibiotics in human healthcare and livestock husbandry has led to trace amounts of the drugs ending up in food products. Long-term consumption could cause health problems, but it's been difficult to analyze more than a few antibiotics at a time because they have different chemical properties. Now, researchers reporting in ACS' Journal of Agricultural and Food Chemistry have deve

Rapid, sensitive diagnosis of COVID-19 is essential for early treatment, contact tracing and reducing viral spread. However, some people infected with SARS-CoV-2 receive false-negative test results, which might put their and others' health at risk. Now, researchers reporting in ACS' Nano Letters have developed ultra-absorptive nanofiber swabs that could reduce the number of false-negative tests by

Ibland visar sig det som först kunde tolkas som Parkinsons sjukdom bero på något annat och betydligt mer aggressivt. Forskarna kallar det atypisk parkinsonism och jobbar intensivt med att förstå de bakomliggande mekanismerna. De flesta av oss vet ungefär vad Parkinson är. Sjukdomen uppstår när kroppen inte klarar att producera tillräckligt med dopamin, en signalsubstans som hjärnans celler använd

The thought of eating insects is stomach turning for many, but new Edith Cowan University (ECU) research is shedding light on allergy causing proteins which could pose serious health risks for those suffering from shellfish allergy.

Novel propulsion systems for CubeSats have been on an innovative tear of late. UT has reported on propulsion systems that use everything from solid iodine to the Earth's own magnetic field as a way of moving a small spacecraft. Now, there is a potential solution using a much more mundane material for a propellant—water.

Jakt med löshund ökar älgens energiförbrukning, vilket på sikt kan öka risken för negativa effekter på kroppskonditionen. Men, om störningarna inte upprepas frekvent, verkar älgen kunna kompensera energiförlusten med att vila och använda mindre energi dagen efter jakt. Runt 80 000 älgar fälls varje år i Sverige, och merparten av dessa jagas med hund. Genom att mäta hjärtfrekvens, kroppstemperatur

The British audio brand's carbon fiber noise-canceling headphones have become my favorite quarantine companion.

Uncover the marvels of the Ancient language and explore the Nebula and the secrets contained within this indie game.

If the president wants to win the race on 5G and other technologies, he'll need more than the support of America's traditional global allies.

There's something utterly wrong with this photo. (Harry Guinness/) With great editing power comes great responsibility—the more easily you can change things about your photos, the more carefully you have to do it. Over the past few years image editing tools have gotten more advanced, more user-friendly, and, in some cases, even completely automatic . Now, with a few clicks you can swap the sky in

Findings will play big role in determining how quickly lockdown can be lifted

Rapid, sensitive diagnosis of COVID-19 is essential for early treatment, contact tracing and reducing viral spread. However, some people infected with SARS-CoV-2 receive false-negative test results, which might put their and others' health at risk. Now, researchers reporting in ACS' Nano Letters have developed ultra-absorptive nanofiber swabs that could reduce the number of false-negative tests by

En daglig gåtur kan forlænge dit liv med op til fire år.

A new method of identifying molecular targets to fight disease could help accelerate future drug development new Griffith University research published in Scientific Reports has found.

Ribosomes are complex molecular machines in the cell that catalyze the production of proteins. Ahmed Badran, a Broad Fellow at the Broad Institute of MIT and Harvard, and his lab aim to engineer new kinds of ribosomes that generate proteins with novel properties.

A new method of identifying molecular targets to fight disease could help accelerate future drug development new Griffith University research published in Scientific Reports has found.

Ribosomes are complex molecular machines in the cell that catalyze the production of proteins. Ahmed Badran, a Broad Fellow at the Broad Institute of MIT and Harvard, and his lab aim to engineer new kinds of ribosomes that generate proteins with novel properties.

Since its launch in September 2016, the OSIRIS-REx spacecraft has traveled billions of miles, mapped the surface of an asteroid in unprecedented detail, and made new scientific discoveries about near-Earth asteroids. Now, it's preparing to bring a piece of asteroid Bennu home.

A research team led by City University of Hong Kong (CityU) has built a mathematical model to explore and analyze the relationship between disease transmission, people's awareness about the disease and their resulting behaviors, as well as information spread by the mass media and opinion leaders. The research may shed some insights on responding to COVID-19 and other similar infectious diseases.

A characteristic feature of all stem cells is their ability to self-renew. But how is this potential maintained throughout life? Scientists at the German Cancer Research Center (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) have now discovered in mice that cells in the so-called stem cell niche are responsible for this: Blood vessel cells of the ni

Tracking milk drinking in the ancient past is not straightforward. For decades, archaeologists have tried to reconstruct the practice by various indirect methods. They have looked at ancient rock art to identify scenes of animals being milked and at animal bones to reconstruct kill-off patterns that might reflect the use of animals for dairying. More recently, they even used scientific methods to

Tomatoes are one of the most popular types of fresh produce consumed worldwide, as well as being an important ingredient in many manufactured foods.

The tree species in the Dipterocarpaceae family dominate many tropical forest formations in Southeast Asia (see Figure 1). The Philippines is home to more than 50 dipterocarp tree species, of which 25 cannot be found anywhere else on Earth. About 97% of the Philippines' tropical forest have been subjected to logging activities, and are often converted to other land uses such as for agriculture. He

As the climate warms and Arctic sea ice retreats, more research vessels and commercial ships are sailing into the Arctic Ocean, but the accuracy and sensitivity of regional weather and marine forecasts for these hazardous waters still lag well behind those of their lower-latitude counterparts, with significant differences between regional models. Direct measurements of atmospheric conditions, such

A characteristic feature of all stem cells is their ability to self-renew. But how is this potential maintained throughout life? Scientists at the German Cancer Research Center (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) have now discovered in mice that cells in the so-called stem cell niche are responsible for this: Blood vessel cells of the ni

Tomatoes are one of the most popular types of fresh produce consumed worldwide, as well as being an important ingredient in many manufactured foods.

The tree species in the Dipterocarpaceae family dominate many tropical forest formations in Southeast Asia (see Figure 1). The Philippines is home to more than 50 dipterocarp tree species, of which 25 cannot be found anywhere else on Earth. About 97% of the Philippines' tropical forest have been subjected to logging activities, and are often converted to other land uses such as for agriculture. He

Landets fem Steno Diabetes Centre har fået 25 mio. kr. til at forske i, hvordan personer med type 2-diabetes adskiller sig fra hinanden.

What a SpaceX Starlink satellite looks like in orbit. SpaceX made history recently when it launched a record 143 satellites on a single rocket . Among the plethora of spacecraft were ten new Starlink internet satellites. According to CEO Elon Musk, these are the first nodes in SpaceX's network that have fully operational laser communication systems , allowing the satellites to talk to each other

Large galaxies are thought to form gradually, across billions of years of cosmic time. So why do astronomers keep finding them in the youthful early universe? — Read more on ScientificAmerican.com

Large galaxies are thought to form gradually, across billions of years of cosmic time. So why do astronomers keep finding them in the youthful early universe? — Read more on ScientificAmerican.com

PLUS. Kun to uger før høring af anlægslov er færdig, er organisationer vågnet op med krads kritik af den parallelle VVM-proces for kæmpeøen.

Modsat flere af landets øvrige regioner ønsker embedsværket i Region Midtjylland fortsat, at højeste pris skal afgøre hvilke læger, som overtager ydernumrene i regionen. Det kan blive en kæp i hjulet på de aktører, som ønsker et opgør med det, PLO betegner som »stråmandsklinikker«.

Latest round of crunch talks to discuss breakdown in supplies still happening, says spokesman Coronavirus – latest updates See all our coronavirus coverage Britain is on a collision course with the EU over vaccine shortages after Brussels refused to accept that people in the UK have first claim on Oxford/AstraZeneca doses produced in local plants. The EU's health commissioner outright dismissed o

The UK needs to learn from the lessons of the past year and come up with a concrete plan to avert a disastrous third wave Coronavirus – latest updates See all our coronavirus coverage Yesterday Britain passed a grim milestone. A further 1,631 deaths from Covid-19 were recorded, taking the official tally above 100,000, though data from the Office for National Statistics suggests the total number w

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00183-z Nature's third progress report, coming at the end of the pandemic's first year, highlights key findings from epidemiology — from sounding the early alarm to following the impact of new variants.

Updated at 9:33 a.m. ET on January 27, 2021. There is a rich historical irony to the fact that today, conservatives are the ones who argue most forcefully that the decisions by private companies to "deplatform" certain speakers threaten what President Donald Trump described in 2020 as the " bedrock " American right to freedom of speech. Until very recently, this was an argument made almost exclus

The Grants Pass Clinic in southern Oregon is more than ready to administer the COVID-19 vaccine to its 20,000-some patients. It has seven exam rooms devoted to vaccination. The staff has ordered fridges and syringes. The phones ring nonstop, with patients calling to ask when they can come in to get their shot. But the clinic has barely any doses to give out. Christi Siedlecki, the CEO of the clin

The victims of the so-called Golden State Killer lived in subdivisions and middle-class neighborhoods. They included a nurse, a medical student, a bank loan officer, and a lawyer shortlisted for a county-court judgeship. Investigators puzzled over these cold cases for more than 30 years. Then, in April 2018, their efforts finally paid off when they identified a suspect, a 72-year-old former polic

Across the globe, SARS-CoV-2 is evolving ways to evade the immune system and become more infectious. Blown pandemic response plans are to blame.

The Historical Dictionary of Science Fiction turns a century of neologisms (and neosemes!) into a redefintion of the genre.

There are times when critically ill patients must wait for beds, and some facilities have contingency plans to limit scarce supplies to certain patients — Read more on ScientificAmerican.com

There are times when critically ill patients must wait for beds, and some facilities have contingency plans to limit scarce supplies to certain patients — Read more on ScientificAmerican.com

Den bolid, rymdsten, som lyste upp himlen över Mellansverige i november förra året gav upphov till ett meteoritfall. Det bekräftar forskare efter att fragment av rymdstenen har hittats och undersökts. Det är det första svenska fyndet efter ett observerat meteoritfall på över 66 år. Klockan 22.27 den 7 november lystes himlen upp under cirka tre sekunder över stora delar av östra Svealand. I västra

Scientific Reports, Published online: 27 January 2021; doi:10.1038/s41598-021-82414-x

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00187-9 Regulators will soon grapple with how to safely administer powerful psychedelics for treating depression and post-traumatic stress disorder.

Indonesia, an archipelago of 270 million people, sits along the Pacific "Ring of Fire," which leaves the country prone to earthquakes, tsunamis and eruptions. (Image credit: Agung Supriyanto/AFP via Getty Images)

When Americans began receiving coronavirus vaccines last month, people started fantasizing about the first thing they'd do when the pandemic ends: go back to work, visit family, hug friends. But the public discussion soon shifted. One news article after another warned about everything that could go wrong: Protection isn't immediate; vaccinated people can still transmit the virus; vaccinated peopl

Method can increase detection rate among infected people, senior Beijing doctor tells state TV Coronavirus – latest updates See all our coronavirus coverage China has begun using anal swabs to test those it considers to be at high risk of contracting Covid-19, state TV has reported. Officials took anal swabs from residents of neighbourhoods with confirmed Covid-19 cases in Beijing last week, acco

Forecast predicts handful of developed countries fully vaccinated by late 2021 while others race to catch up Coronavirus – latest updates See all our coronavirus coverage Most poor countries will not achieve mass Covid-19 immunisation until at least 2024 and some may never get there, according to a new forecast, which maps a starkly divided world over the next few years in which a handful of deve

One of the many fun things about reporting on retractions is that we get to expand our statistical knowledge. To wit, follow along as we explore the concept of immortal time bias. A JAMA journal has retracted and replaced a paper by authors at the University of Massachusetts after another researcher identified a critical statistical … Continue reading

Scientific Reports, Published online: 27 January 2021; doi:10.1038/s41598-021-82641-2

Scientific Reports, Published online: 27 January 2021; doi:10.1038/s41598-021-81783-7

Scientific Reports, Published online: 27 January 2021; doi:10.1038/s41598-021-81913-1

Scientific Reports, Published online: 27 January 2021; doi:10.1038/s41598-021-82046-1

Scientific Reports, Published online: 27 January 2021; doi:10.1038/s41598-021-82079-6

Scientific Reports, Published online: 27 January 2021; doi:10.1038/s41598-021-82034-5

Scientific Reports, Published online: 27 January 2021; doi:10.1038/s41598-021-81956-4

Scientific Reports, Published online: 27 January 2021; doi:10.1038/s41598-021-82192-6

Virus har stadig rum til at udvikle sig. Men firmaerne melder nu ud, at de forbereder booster-skud, der skal dække mutationer som den sydafrikanske.

After just a week in office, the Biden administration is already under immense public pressure to fix America's mangled vaccine rollout. Operation Warp Speed injected enormous sums into developing vaccines but left most of the planning—and cost—of administering them to states, which are now having to cope with the fallout. The reliance on chronically underfunded health departments has exposed a t

When Daniella Chusy, currently at Indiana University, U.S., learned that many captive elephants were thought to be overweight and that their low birth rates suggested that they may be facing a fertility crisis, she began seeing parallels with the obesity crisis humans face currently. But no one had actually measured how much fat captive Asian elephants (Elephas maximus) in zoos carry. "I was inter

When Daniella Chusy, currently at Indiana University, U.S., learned that many captive elephants were thought to be overweight and that their low birth rates suggested that they may be facing a fertility crisis, she began seeing parallels with the obesity crisis humans face currently. But no one had actually measured how much fat captive Asian elephants (Elephas maximus) in zoos carry. "I was inter

Nature Communications, Published online: 27 January 2021; doi:10.1038/s41467-020-20888-5 Chiral benzylamines are found in many pharmacologically active molecules. Here, the authors report an enantio- and regio-selective reductive hydroarylation of N-acyl enamines with a NiH/chiral bis-imidazoline catalytic system affording a range of enantioenriched benzylamines.

Nature Communications, Published online: 27 January 2021; doi:10.1038/s41467-020-20371-1 Neural recording technologies increasingly enable simultaneous measurement of neural activity from multiple brain areas. To gain insight into distributed neural computations, a commensurate advance in experimental and analytical methods is necessary. We discuss two opportunities towards this end: the manipula

Nature Communications, Published online: 27 January 2021; doi:10.1038/s41467-020-20883-w Pioneer transcription factors access their DNA binding motifs in closed chromatin and often act in cell fate reprogramming. Here, Jin et al. present biochemical evidence for a pioneer factor in plants and show that LFY promotes floral cell fate and locally unlocks chromatin by displacing histone H1 and recrui

Nature Communications, Published online: 27 January 2021; doi:10.1038/s41467-020-20657-4 The SARS-COV-2 pandemic has put pressure on intensive care units, so that predicting severe deterioration early is a priority. Here, the authors develop a multimodal severity score including clinical and imaging features that has significantly improved prognostic performance in two validation datasets compare

Nature Communications, Published online: 27 January 2021; doi:10.1038/s41467-021-20898-x The flexibility of memory updating may be determined in the initial memory consolidation process. Here, the authors show the proteomic changes of the transcriptional repressor complexes required for initial memory consolidation and influencing the flexibility of future memory updating.

Nature Communications, Published online: 27 January 2021; doi:10.1038/s41467-021-20919-9 Ubiquitous shadows cast from moving objects in hybrid energy-harvesting systems are undesirable as they degrade the performance of the photovoltaic cells. Here the authors report the shadow of the moving object in a hybrid energy-harvesting system shortens charging time to charge a self-charging power system.

Nature Communications, Published online: 27 January 2021; doi:10.1038/s41467-020-20596-0 Archaerhodopsin-3 (AR3) mutants are commonly used in optogenetics for neuron silencing and membrane voltage sensing. High-resolution crystal structures show that desensitization of the AR3 photoreceptor occurs when internal hydrogen-bonded water networks are modified in response to changes in chromophore isom

Nature Communications, Published online: 27 January 2021; doi:10.1038/s41467-021-20938-6 Liquid crystalline network (LCN) actuators switch reversibly between two states. Here, the authors report an asymmetrically processed LCN actuator which allows desynchronized actuation between three states using light and thermal stimuli.

Heart disease remains the #1 cause of death worldwide in the latest annual Statistical Update from the American Heart AssociationExperts say the effects of COVID-19 are likely to influence cardiovascular health and mortality rates for many years, directly and as a result of increased lifestyle-related risks during and after the pandemic.

Much of the earth's carbon is trapped in soil, and scientists have assumed that potential climate-warming compounds would safely stay there for centuries. But new research from Princeton University shows that carbon molecules can potentially escape the soil much faster than previously thought. The findings suggest a key role for some types of soil bacteria, which can produce enzymes that break dow

A characteristic feature of all stem cells is their ability to self-renew. But how is this potential maintained throughout life? Scientists at the German Cancer Research Center (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine* (HI-STEM) have now discovered in mice that cells in the so-called "stem cell niche" are responsible for this,

Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN. Their experiments revealed that TALEN is up to five times more efficient than CRISPR-Cas9 in parts of the genome, called heterochromatin, that are densely packed. Fragile X syndrome, sickle cell anemia, beta-thalassemia and other diseases are the result of genetic defects in the heterochromatin.

Got milk? The 1990s ad campaign highlighted the importance of milk for health and wellbeing, but when did we start drinking the milk of other animals? And how did the practice spread? A new study led by scientists from Germany and Kenya highlights the critical role of Africa in the story of dairying, showing that communities there were drinking milk by at least 6,000 years ago.

In a small study, stroke survivors who completed a three-month cardiac rehabilitation program focused on aerobic exercise significantly improved their physical endurance and strength.Six months after the program more, 83.3% of participants reported that they continued exercising at least once a week.

Serious efforts to address global warming might mean big changes for America's trade, foreign relations and even defense strategy.

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00190-0 University policies often present barriers to bringing assistance dogs into the lab or on campus.

Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN. Their experiments revealed that TALEN is up to five times more efficient than CRISPR-Cas9 in parts of the genome, called heterochromatin, that are densely packed. Fragile X syndrome, sickle cell anemia, beta-thalassemia and other diseases are the result of genetic defects in the heterochromatin.

Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN. Their experiments revealed that TALEN is up to five times more efficient than CRISPR-Cas9 in parts of the genome, called heterochromatin, that are densely packed. Fragile X syndrome, sickle cell anemia, beta-thalassemia and other diseases are the result of genetic defects in the heterochromatin.

Much of the earth's carbon is trapped in soil, and scientists have assumed that potential climate-warming compounds would safely stay there for centuries. But new research from Princeton University shows that carbon molecules can potentially escape the soil much faster than previously thought. The findings suggest a key role for some types of soil bacteria, which can produce enzymes that break dow

Study of ancient Africans suggests dairy consumption predated evolution of lactase persistence genes

Since the pandemic began, hundreds of Medical Reserve Corps units have deployed volunteers to help with the Covid-19 response. They have since logged hundreds of thousands of volunteer hours, often with little public recognition. But some public health experts say the program is underutilized.

PLUS. Den 500 meter lange protonaccelerator er gemt af vejen under et græsdække, og tre ton wolfram udgør hjertet i target-bygningen.

Nature, Published online: 27 January 2021; doi:10.1038/d41586-021-00186-w The latest science news, in brief.

US President Joe Biden was planning to announce new bans on oil and gas drilling on federal lands Wednesday as part of a raft of actions that take aim at climate change, according to reports and a White House memo.

Forskare vid Lunds universitet tror sig ha identifierat en genvariant som kan orsaka småkärlssjukdom i hjärnan och stroke.

Indonesia's most active volcano erupted Wednesday with a river of lava and searing gas clouds flowing 1,500 meters (4,900 feet) down its slopes.

Harpy eagles are considered by many to be among the planet's most spectacular birds. They are also among its most elusive, generally avoiding areas disturbed by human activity—therefore already having vanished from portions of its range—and listed by the International Union for the Conservation of Nature (IUCN) as being 'Near-Threatened'.

Harpy eagles are considered by many to be among the planet's most spectacular birds. They are also among its most elusive, generally avoiding areas disturbed by human activity—therefore already having vanished from portions of its range—and listed by the International Union for the Conservation of Nature (IUCN) as being 'Near-Threatened'.

Multi-disciplinary researchers at The University of Manchester have helped develop a powerful physics-based tool to map the pace of language development and human innovation over thousands of years—even stretching into pre-history before records were kept.

The United States Department of Agriculture identifies a group of "big eight" foods that causes 90% of food allergies. Among these foods are wheat and peanuts.

A material that can be used in technologies such as solar power has been found to self-heal, a new study shows.

The United States Department of Agriculture identifies a group of "big eight" foods that causes 90% of food allergies. Among these foods are wheat and peanuts.

Like Einstein, Galileo, and Copernicus, former NASA program manager Craig Tooley now has a place on the Moon named in his honor. Tooley crater is a 7 km crater in a permanently shadowed region of Shoemaker crater near the lunar south pole. The new crater designation is official and can be used in journal articles and other publications.

Israel's leader sees long race ahead between Covid vaccinations and mutations

The results of the Peoples' Climate Vote, the world's biggest ever survey of public opinion on climate change are published today. Covering 50 countries with over half of the world's population, the survey includes over half a million people under the age of 18, a key constituency on climate change that is typically unable to vote yet in regular elections.

I et nyt studie undersøger forskere fra Københavns Universitet for første gang nogensinde,…

US states to get boost in vaccine next week ; Germany considering stopping most flights to country ; global coronavirus cases pass 100m UK hotel quarantine system to target travellers from high-risk areas New Zealand: two new cases emerge in people who had left quarantine German government challenges reports on AstraZeneca vaccine Why experts say there is no basis to AstraZeneca jab claims See al

Should I worry about my addiction to 1,000-piece brainteasers? Not according to the scientists If you looked at my Google search history (which I would obviously never let anyone do), an alarming percentage of it would consist of variations of: "Is X actually good for you?" With X being whichever bad habit I'm engaged in. The amazing thing about the internet is that you can always find a random s

Uddannelse på KU er ikke kun lange, sammenhængende forløb, men også efteruddannelse…

This is awesome.

Social media as an epidemiological tool.

More than a million people in 50 countries take part in the biggest poll to date on climate change.

Taking cannabidiol, a chemical in the cannabis sativa plant, isn't an effective way to reduce your dependence on cocaine, researchers at the CHUM Research Centre find.

Study explores lateralization changes in resting state brain network functional connectivity. Among military service members and Veterans with symptoms of traumatic stress, asymmetries of network and brain region connectivity patterns were identified prior to usage of HIRREM. A variety of changes in lateralized patterns of brain connectivity were identified post intervention. These laterality find

A physics professor has joined forces with language experts to build a 'linguistic thermometer' that can record the temperature of 'hot' or 'cold' (ie fast or slow) developments in modern linguistic features to create a computer-based model that can provide a better understanding of the development in human language and innovation stretching back to pre-history.

New research led by the University of Plymouth (UK) suggests estimates of the species' current distribution are potentially overestimating range size.

Children of all ages can completely bypass age verification measures to sign-up to the world's most popular social media apps including Snapchat, Instagram, TikTok, Facebook, WhatsApp, Messenger, Skype and Discord by simply lying about their age, researchers at Lero, the Science Foundation Ireland Research Centre for Software have found.

A research team led by University of Tsukuba has produced genome sequences for two wild species of tomato from South America, ancestors of the cultivated tomato. The ancestral species contain thousands of genes that are not present in modern types. The novel genes will help plant breeders produce new tomatoes with features like improved disease resistance, increased tolerance for the changing clim

Research uses plant breeding and biotechnology to remove proteins associated with food allergies.

Wildfires are the enemy when they threaten homes in California and elsewhere. But a new study led by SMU suggests that people living in fire-prone places can learn to manage fire as an ally to prevent dangerous blazes, just like people who lived nearly 1,000 years ago.

An innovative UNDP global survey conducted in collaboration with Oxford University experts — the largest-ever opinion survey on climate change (1.2 million people in 50 countries) — finds 64% (+/- 2%) deem climate an 'emergency.' Worldwide, most people clearly want a strong and wide-ranging policy response, and 4 of 18 policy options received majority support.Distributed across mobile gaming net

Whew.

New technologies can bring benefits both to the poorest parts of the planet and to investors

A newly-published global survey of national health authority websites in nearly 200 countries has directly quantified COVID-19 information accessibility. Only a few of the countries examined fully adhered to internationally recognized accessibility guidelines. Websites from the majority of countries surveyed continue to contain accessibility errors that present significant barriers to people with

23. september 2020 skulle offentlige sites overholde krav om webtilgængelighed. Men siderne får en score på 76 procent i en bred stikprøve, Version2 har udført. Skuffende, mener handicaporganisation. Vi er længst fremme i EU, svarer styrelse.

There are markedly different outcomes for different species of coral reef fishes under climate change – scientists are now another step closer to uncovering the 'winners and losers'.

After an initial report told of collapsing food webs in Puerto Rico, a group of researchers conducting long-term research on the island took a closer look at the issue.

In a study of 500 sourdough starters spanning four continents, scientists have garnered new insights into the environmental factors that contribute to each sourdough starter's microbial ecosystem, and how different types of microbes influence both a sourdough's aroma and how quickly the sourdough rises. The results may surprise sourdough enthusiasts.

Scientists have designed a single-dose universal vaccine that could protect against the many forms of leptospirosis bacteria, according to a new study.

Although the protein ITIH4 is found in large amounts in the blood, its function has so far been unknown. By combining many different techniques, researchers have discovered that ITIH4 inhibits proteases in the innate immune system via an unknown mechanism.

PLUS. Elektrificeringsrapport fra DTU bekræfter store potentialer for elektrificering af industrier og også Klimarådet har i brev til Energinet problematiseret gasprojektet

Design of aerial vehicles and weapon systems relies on the ability to predict aerodynamic behavior, often aided by advanced computer simulations of the flow of air over the body. High-fidelity simulations assist engineers in maximizing how much load a rotorcraft can lift or how far a missile can fly, but these simulations aren't cheap. A new turbulence model could change that.

Teenagers with happy childhood memories are likely to drink less, take fewer drugs and enjoy learning, according to new research.

Extreme weather events, such as hurricanes and increased precipitation, affect both the amount and the composition of picophytoplankton in the Neuse River Estuary. The work is a first step in determining how a wetter climate may affect the estuarine ecosystem.

A new study presents a prototype Rate-State earthquake simulator that simulates hundreds of thousands of years of seismic history in California. Coupled with another code, the framework can calculate the amount of shaking that would occur for each quake. The new approach improves the ability to pinpoint how big an earthquake might occur in a given location, allowing building code developers and st

Mosses and flowering plants took different genetic routes to evolve a similar defense mechanism.

Researchers have observed the entire sequence in break-induced replication, a method by which organisms from viruses to humans repair breaks in DNA that cannot be fixed otherwise but can introduce or cause genomic rearrangements and mutations contributing to cancer development.

New research shows that there are two phases of wall restructuring after an aneurysm forms, the first beginning right away to reinforce the weakened points.

Food for thought.

With a clever experiment, physicists have shown that in a one-dimensional quantum system, the initially complex distribution of vibrations or phonons can change over time into a simple Gaussian bell curve.

Scientists analyzed where and when thousands of genes are activated in baby corn. This allowed them to build an anatomical map of important developmental genes that can be manipulated to improve crop yield and resilience.

Landslides caused by the collapse of unstable volcanoes are one of the major dangers of volcanic eruptions. A method to detect long-term movements of these mountains using satellite images could help identify previously overlooked instability at some volcanoes, according to scientists.