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Science | The Guardian
In the search for Covid protection, Cormac the 'extremely charismatic' llama may hold a key
 
The llama has provided nanobodies that effectively prevent infection, but the use of other species in Covid research raises troubling ethical questions Cormac the llama lives a quiet life on a farm in Washington State, totally unaware that his unique immune system may be key to protecting the developing world from Covid-19. "He is an extremely charismatic llama … he's a pretty cool guy," says TJ
15min
ScienceDaily
New report charts path toward superior earthquake recovery
 
A committee of experts has urged officials at all levels of government to support research and policies that could help get the buildings and services society depends on up and running quickly after an earthquake. In a report delivered to Congress, the committee outlines seven recommendations that, if acted upon, may greatly improve the resilience of communities across the nation.
40min
ScienceDaily
A metalens for virtual and augmented reality
 
Researchers have developed a two-millimeter achromatic metalenses that can focus RGB (red, blue, green) colors without aberrations and developed a miniaturized display for virtual and augmented reality applications.
40min
Science | The Guardian
Over-70s in UK 'will die' if Covid vaccine priority goes to younger key workers
 
Government advisers say it would be 'politically, socially and ethically unacceptable' not to inoculate older people first Coronavirus – latest updates See all our coronavirus coverage Prioritising vaccinations for key workers such as teachers and police over the next few weeks would inevitably lead to more deaths among older people, government vaccination advisers have warned. There have been va
56min
ScienceDaily
How breast cancer cells hide from immune attack
 
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified how breast cancer cells hide from immune cells to stay alive. The discovery could lead to better immunotherapy treatment for patients.
1h
ScienceDaily
Pain patients who take opioids can't get in the door at over half of primary care clinics
 
People who take opioid medications for chronic pain may have a hard time finding a new primary care clinic that will take them as a patient if they need one, according to a new 'secret shopper' study of hundreds of clinics across the country. Stigma against long-term users of prescription opioids, likely related to the prospect of taking on a patient who might have an opioid use disorder or addict
1h
Popular Science | RSS
Backyard party essentials: Outdoor Super Bowl party ideas for 2021
 
Everything you'll need for your socially-distanced Super Bowl party. (Alex Litvin via Unspalsh/) The past year has seen the world struggle to return to some semblance of normalcy as public events, group gatherings, and even dining have been restricted or shut down entirely. Sports have prevailed, however, and despite some jarring changes, the major sports leagues have managed to provide a respite
2h
Science | The Guardian
Is there life on Mars? Not if we destroy it with poor space hygiene
 
As countries begin an age of Martian exploration, planetary protection advocates insist we must be careful of interplanetary contamination Next month, three new spacecraft arrive at Mars. Two represent firsts for their countries of origin, while the third opens a new era of Mars exploration. The first is the UAE's Emirates Mars Mission, also known as Hope, which enters orbit on 9 February. Shortl
2h
The Atlantic
They Called for Help. They'd Always Regret It.
 
Photographs by Arlene Mejorado and Carlos Chavarr í a W hen Antonietta Zuñiga woke up to smoke pouring through her bedroom window, everything she had learned about how to care for her grandson completely left her mind. It was November 2019, in the Los Angeles County city of Pico Rivera. Antionetta's grandson, Carlos Zuñiga Jr., is schizophrenic; she had the number for ACCESS, L.A. County's mental
2h
Science | The Guardian
'Find of the century': medieval hoard of treasures unearthed in Cambridge
 
Graves found under demolished student halls are providing valuable insight into life in a post-Roman settlement An early medieval graveyard unearthed beneath student accommodation at Cambridge University has been described as "one of the most exciting finds of Anglo-Saxon archaeology since the 19th century". King's College discovered the "extensive" cemetery, containing more than 60 graves, after
3h
EurekAlert! – Breaking News
TALENT study supports NLCST and NELSON trial results
 
A study presented today by researchers with the Ministry of Health and Welfare in Taiwan confirmed the effectiveness of low-dose computed tomography (LDCT) screening in a pre-defined, never-smoker, high-risk population. The research was presented today at the International Association for the Study of Lung Cancer 2021 World Conference on Lung Cancer.
3h
EurekAlert! – Breaking News
LCMC3: Neoadjuvant atezolizumab safe, meets primary endpoint of pathologic response rate
 
Primary analysis of the Lung Cancer Mutation Consortium (LCMC) 3 study revealed that neoadjuvant atezolizumab prior to lung cancer surgery was well tolerated by patients and met its primary endpoint of 20% major pathologic response rate, according to research presented today at the International Association for the Study of Lung Cancer's World Conference on Lung Cancer.
3h
EurekAlert! – Breaking News
Selected gene mRNA expression is not predictive of improved overall survival
 
)– A phase III study examining whether messenger (m)RNA expression correlated with sensitivity or resistance to chemotherapy did not confer a statistically significant advantage in overall survival for patients with resected stage II-III non-small cell lung cancer (NSCLC), according to research presented at the International Association for the Study of Lung Cancer World Conference on Lung Cancer
3h
Science | The Guardian
How I found the special joy of nature in cities | Alice Vincent
 
You have to look – and sometimes very closely – but discovering small patches of woodland or flowers bursting through concrete makes me appreciate nature all the more One Friday morning last October, when we still could, I drove down from Brixton in south London to Somerset. It was one of those autumn days people anticipate in the midst of a sticky summer, with pillowy mist and low-lying sun tryi
4h
Singularity Hub
This Week's Awesome Tech Stories From Around the Web (Through January 30)
 
3D PRINTING A Real 3D-Printed Home Listing Just Popped Up on Zillow for a Cool $300,000 Sam Rutherford | Gizmodo "Unlike many smaller 3D-printed abodes, the Riverhead home was built on-site rather than constructed in a warehouse and then later transported to the plot. Designed by H2M and built by SQ4D Inc., the Riverhead home was also constructed using autonomous robotic construction systems (ARC
4h
Science | The Guardian
Two new Covid vaccines have less efficacy against South African strain
 
Early trial data shows Novavax and Johnson & Johnson vaccines have much less efficacy against new variant Early data from two new coronavirus vaccine trials has indicated that they have less efficacy at protecting from the South African variant of coronavirus. Clinical trial data showed that the vaccines from Novavax and Johnson & Johnson had significantly less efficacy at preventing coronavirus
4h
The Atlantic
The Explosive Song That Liberated Tina Turner
 
Jack Robinson / Hulton Archive / Getty Before a concert one night in 1968, shortly prior to recording the song that would launch her into superstardom, Tina Turner swallowed sleeping pills and lay down to die. "People backstage noticed something was very wrong with me and rushed me to the hospital, which saved my life," she writes in her book Happiness Becomes You , published in the fall . "At fi
6h
Ingeniøren
Kronik: Skønheden i matematikken
 
PLUS. »Man forstår ikke for alvor matematik, hvis ikke man ejer en digters sjæl,« sagde den russiske matematiker Sofia Kovalevskaya (1850-1891). Civilingeniør Jacob Grønlykke opfordrer til erkendelse i undervisningen.
6h
The Atlantic
Only Accountability Will Allow the U.S. to Move Forward
 
A white mob stormed government offices in an effort to overthrow the duly elected leadership, overwhelming the local police and killing several officers in a violent clash. This description is not only of the insurrection in Washington, D.C., on January 6, but of the Battle of Liberty Place in New Orleans, on September 14, 1874. The Crescent City White League, a white-supremacist group made up of
7h
The Atlantic
The Government Didn't Foresee How Facebook Would Behave
 
The U.S. government almost never jumps at its first chance to confront an emerging monopoly. But regulators have a long history of getting it right the second time. Standard Oil controlled America's petroleum market for years before the Justice Department sued the company under the Sherman Antitrust Act; the federal government helped enshrine AT&T's telephone monopoly for decades before deciding
8h
The Atlantic
Xi Jinping: Man of Mystery
 
"Living in China is confusing now," the novelist Yan Lianke said, "because it can feel like being in North Korea and the United States at the same time." I recall smiling and nodding when he made the remark, during a roundtable discussion at Duke University's campus outside Shanghai three years ago. In one brief sentence, he captured just how special and strange China can seem—a country that has
8h
MIT Technology Review
What went wrong with America's $44 million vaccine data system?
 
The first time Mary Ann Price logged into her employer's system to schedule a vaccine, she found an appointment three days later at a nearby Walgreens pharmacy. She woke up the next day to an email saying it had been canceled. So she logged in again and found an opening that afternoon at the local surgical hospital. "When I showed up, they said they wouldn't honor it—they were only doing their ow
8h
Popular Science | RSS
Fujifilm's new 102-megapixel camera is the size of a typical DSLR
 
Because of its size and weight, you wouldn't guess there was a medium format sensor inside. (Fujifilm/) Back in 2019, Fujifilm released its first entry into the 100-megapixel medium format camera space. The GFX 100 was a beastly, $10,000 body with an integrated grip-style body similar to a pro DSLR like Canon's 1D X Mark III or Nikon's D6 . This week, however, the company took some big steps towa
9h
Science | The Guardian
WHO's Covid warnings were not heeded. Now the world has a new chance to beat the virus
 
If nations make vaccine delivery equitable, step up testing and study variant genomes, the pandemic could be under control by January 2022 Coronavirus – latest updates See all our coronavirus coverage A year ago, on 30 January, the World Health Organization declared the outbreak of the new coronavirus a public health emergency of international concern – the highest level of alarm at our disposal
12h
Future(s) Studies
"What is human civilization trending towards?" My opening statement from the debate. I had a great time and thank the Mods for the open format that let us all participate and share our ideas.
 
TEAM REALISTS OPENING STATEMENT "What is human civilization trending towards?" My predictions are for the next 10 years and I see 5 main categories where we will likely see major changes: Health Services In the next 10 years I predict more countries will use a Telemed like service so people will not have to go to a doctors office for basic health care and prescriptions and this will happen online
12h
Future(s) Studies
/r/Collapse & /r/Futurology Debate – What is human civilization trending towards?
 
Welcome to the third r/Collapse and r/Futurology debate! It's been three years since the last debate and we thought it would be a great time to revisit each other's perspectives and engage in some good-spirited dialogue. We'll be shaping the debate around the question "What is human civilization trending towards?" This will be rather informal. Both sides have put together opening statements and r
12h
Science | The Guardian
Weatherwatch: does lightning strike on Venus?
 
Flash of light detected on planet, about 10 times more energetic than lightning on Earth, reopens debate Does lightning strike on Venus? It's a question that has perplexed planetary scientists for decades. Given that lightning has been detected in the clouds of Jupiter, Saturn and Uranus, you'd expect lightning to occur on Venus, too, but the planet's dense clouds ensure that any lightning remain
13h
Science | The Guardian
'Doing a great job': Johnson hails parents for efforts in lockdown
 
PM pens letter recognising 'unique challenges' faced by those looking after children during the pandemic Coronavirus – latest updates See all our coronavirus coverage Keeping children entertained can be an arduous task at the best of times, let alone when families are stuck at home for days on end as a result of the Covid lockdown. In recognition of the "unique challenges" faced by parents, carer
13h
EurekAlert! – Breaking News
Study finds potential therapeutic targets to inhibit colorectal cancer progression
 
Nagoya University researchers and colleagues have revealed that colorectal cancer tissues contain at least two types of fibroblasts, namely, cancer-promoting fibroblasts and cancer-restraining fibroblasts, and that the balance between them is largely involved in the progression of colorectal cancer. Their findings suggest that artificially altering the balance between the two types of cells could
13h
Vetenskap | SVT Nyheter
Hårbehandling innehåller cancerframkallande ämne
 
En pågående undersökning har upptäckt det cancerframkallande ämnet formaldehyd i hårprodukter som används i keratinbehandlingar. Trots att formaldehyd förbjöds i kosmetiska produkter förra året, letar kunder fortfarande efter starkare behandlingar. – Kunder frågar om jag använder en förbjuden keratinprodukt flera gånger per månad. Jag säger att det inte är bra för min hälsa, men de vill ändå ha ju
14h
EurekAlert! – Breaking News
Radiation Oncology trials using PET with FDG uptake among NSCLC patients
 
Two radiation oncology trials presented at the IALSC World Conference on Lung Cancer Singapore highlight how some researchers are exploring use of higher radiation boost doses to only PET-positive regions in locally-advanced non-small cell lung cancer (NSCLC). A previous large RTOG phase III trial revealed that the unform delivery of a high dose to the entire tumor led to poorer survival.
17h
Big Think
Study: Language (not geography) major force behind India's gene flow
 
Studies focusing on European genetics have found a strong correlation between geography and genetic variation. Looking toward India, a new study found a stronger correlation between gene variation and language as well as social structure. Understanding social and cultural influences can help expand our knowledge of gene flow through human history. When we think about our ancestors, our minds tend
17h
The Atlantic
What's the Use of a Pretty Good Vaccine?
& Johnson Vaccine
•
 
Editor's Note: The Atlantic is making vital coverage of the coronavirus available to all readers. Find the collection here . Last spring and summer, when a COVID-19 vaccine was only a glimmer of hope on the horizon, scientists warned in their careful way that vaccines might not live up to the public's high expectations. The FDA said a vaccine needed to be just 50 percent effective. The most impor
18h
Futurism
Microbes Are Making Merry on Your Mattress. But These Bed Sheets Can Put a Stop to It.
 
If you had any idea how many bacteria, germs, and other microbes were festering on your towels and sheets it would probably be enough to make you move into some underground germ-free research facility out of The Andromeda Strain . Fortunately, you don't have to go to such impossible lengths to free yourself from 99.9 percent of the microbes that use your bed sheets and towels as a petri dish. Ins
20h
Popular Science | RSS
What you can do right now to protect yourself from the new COVID-19 variants
 
The more the virus mutates, the more chances it has to evade one of our vaccines. So here's what you can do right now to protect yourself from getting a new COVID-19 variant. (Pixabay/) There's been a lot of talk going around about new variants of COVID-19. To date, scientists have identified more than 4,000 COVID-19 variants over this past year. Some of these strains, including the one that orig
20h
Big Think
Does fact-checking really work? Timing matters.
 
MIT researchers conducted a study with 2,683 volunteers on the efficacy of fact-checking. Showing "true" or "false" tags after the headline proved more effective than showing it before or during . The researchers believe this counterintuitive discovery could lead to better fact-checking protocols in the future. Not only do most people get their news from social media, a majority of users never ma
20h
Science | The Guardian
Coronavirus live news: EU vaccine export controls spark anger in UK and Australia
EU AstraZeneca Vaccine UK
•
 
Shock and anger at EU's move to invoke Brexit clause on Irish border ; Fauci says 'virus will continue to mutate' as Democrats aim to fast-track Covid relief plan ; Johnson & Johnson one-dose Covid vaccine shown to work Oxford/AstraZeneca Covid vaccine given full approval by EU regulator 'Immunological unicorn': the Australian lab growing coronavirus – and its startling discovery US children will
21h
Futurism
New Details Emerge About FAA's Shutdown of SpaceX Starship Launch
 
Starship Shutdown Yesterday, SpaceX had been planning a high altitude flight test of its experimental Starship spacecraft, which is intended to shuttle passengers and cargo into Earth's orbit and even as far as the Moon and Mars. But its plans were halted by the Federal Aviation Administration, which shut down the planned launch — prompting an enraged response from SpaceX CEO Elon Musk. SpaceX tr
21h
ExtremeTechExtreme – ExtremeTech
Phosphine Detected in Venus's Atmosphere May Have Just Been Sulfur
 
The potential discovery of phosphine in Venus's atmosphere last year made headlines around the world. On Earth, phosphine is produced by living things. Any detection of it inside another planet's atmosphere would be a strong potential indicator of life. One reason folks got excited about the possibility is that Venus's upper atmosphere is a much friendlier place for life to exist than its lower c
21h
ScienceDaily
A NEAT reduction of complex neuronal models accelerates brain research
 
Unlike their simple counterparts in artificial intelligence (AI) applications, neurons in the brain use dendrites – their intricate tree-like branches – to find relevant chunks of information. Now, neuroscientists have discovered a new computational method to make complex dendrite models much simpler. These faithful reductions may lead AI applications to process information much like the brain doe
21h
ScienceDaily
A newly discovered circuit helps fish to prioritize
 
Being constantly flooded by a mass of stimuli, it is impossible for us to react to all of them. The same holds true for a little fish. Which stimuli should it pay attention to and which not? Scientists have now deciphered the neuronal circuit that zebrafish use to prioritize visual stimuli. Surrounded by predators, a fish can thus choose its escape route from this predicament.
21h
ScienceDaily
'Achilles' heel' of cancer cells revealed
 
A new study shows, for the first time, how an abnormal number of chromosomes (aneuploidy) — a unique characteristic of cancer cells that researchers have known about for decades — could become a weak point for these cells. The study could lead to the development of future drugs that will use this vulnerability to eliminate the cancer cells.
21h
Popular Science | RSS
Razer's new gaming mouse pings your computer 8,000 times a second to fight lag
 
Razer's RGB lights endure. (Razer/) Non-gamers often find themselves surprised at just how many tech specs a computer mouse can have. Peruse the product page for a competition-grade mouse and you'll find numbers like sensor DPI, which goes up into the thousands, or polling rate, which determines how often your device talks to your computer during use. Most gaming mice boast a polling rate between
21h
ScienceDaily
How is human behavior impacting wildlife movement?
 
For species to survive in the wild, maintaining connectivity between populations is critical. Without 'wildlife corridors', groups of animals are isolated and may die out. In assessing wildlife connectivity, many aspects of the landscape are measured, but the impact of human behavior has largely been overlooked.
22h
Futurism
Freezer Failure Prompts Madcap Vaccine Giveaway
 
After a freezer storing doses of the Moderna vaccine broke down at a Seattle medical center, healthcare workers and volunteers scrambled to dole out as many vaccinations as possible before they went bad. Experts still haven't determined why the freezer failed, The Seattle Times reports . But the end result was a mad dash of people clamoring for a shot, cheering when others were chosen from the cr
22h
Big Think
Study: Personal anecdotes are more effective at bridging divides than facts
 
A new study has found that people are more likely to get respect from others in moral and political conversations when sharing personal experiences instead of facts. The research group conducted 15 separate experiments to test this theory in order to learn more about tolerance in specifically political arguments. The effectiveness of facts in these conversations (even when proven true) is unclear
22h
Popular Science | RSS
Best home security system: Keep your family and property safe
 
Keep your home safe! (Stephan Bechert via Unsplash/) There is nothing better than feeling safe in your home. Unfortunately, a simple bolted door doesn't always deliver the peace of mind it should, and you need to bolster your defenses. The best home security systems are considerably simpler to set up now than just a few years ago, with easy-to-install DIY cameras, monitors, and other accessories.
22h
Phys.org
Specific bacteria in the gut prompt mother mice to neglect their pups
 
As scientists learn more about the microorganisms that colonize the body—collectively called the microbiota—one area of intense interest is the effect that these microbes can have on the brain. A new study led by Salk Institute scientists has identified a strain of E. coli bacteria that, when living in the guts of female mice, causes them to neglect their offspring.
22h
Biology News – Evolution, Cell theory, Gene theory, Microbiology, Biotechnology
Specific bacteria in the gut prompt mother mice to neglect their pups
 
As scientists learn more about the microorganisms that colonize the body—collectively called the microbiota—one area of intense interest is the effect that these microbes can have on the brain. A new study led by Salk Institute scientists has identified a strain of E. coli bacteria that, when living in the guts of female mice, causes them to neglect their offspring.
22h
Phys.org
Dewdrops on a spiderweb reveal the physics behind cell structures
 
As any cook knows, some liquids mix well with each other, but others do not. For example, when a tablespoon of vinegar is poured into water, a brief stir suffices to thoroughly combine the two liquids. However, a tablespoon of oil poured into water will coalesce into droplets that no amount of stirring can dissolve. The physics that governs the mixing of liquids is not limited to mixing bowls; it
22h
EurekAlert! – Breaking News
Women who develop high blood pressure after birth at greater risk of chronic hypertension
 
In a new study to be presented today at the Society for Maternal-Fetal Medicine's (SMFM) annual meeting, The Pregnancy Meeting™, researchers from the University of Pittsburgh will unveil findings that suggest that women who develop high blood pressure during pregnancy and who continue to have elevated blood pressure postpartum are at an increased risk for developing chronic hypertension.
22h
ScienceDaily
Scientists jump-start two people's brains after coma
 
In 2016, a team reported that a 25-year-old man recovering from a coma had made remarkable progress following a treatment to jump-start his brain using ultrasound. Now, researchers report that two more patients with severe brain injuries have also made impressive progress thanks to the same technique.
22h
EurekAlert! – Breaking News
Scientists solve long-standing mystery by a whisker
 
A team of neuroscientists at the University of California, Riverside, has experimented on mice to identify the brain region that functions beyond sensory encoding and motor encoding, potentially opening up new directions to studying the cellular and circuit mechanisms of sensory-motor transformations. The researchers report a cortical region traditionally defined as whisker motor cortex in mice is
22h
EurekAlert! – Breaking News
COVID-19 news from Annals of Internal Medicine
 
1. Study finds Black race higher risk factor for COVID-19 infection than occupational exposureA large survey of health care workers found that community and demographic factors, such as contact with a confirmed or suspected COVID-19-positive case outside the workplace and Black race, were stronger predictors of COVID-19 infection than occupational exposure. The findings are published in Annals of
22h
Futurism
Wealthy Couple Who Stole Indigenous Community's Vaccine Could Be Jailed
 
The wealthy Canadian couple who conned their way into getting coronavirus vaccines meant for the indigenous community in Canada's Yukon territory may now face jail time. Casino executive Rodney and actress Ekaterina Baker took a private plane to the remote community, where they pretended to be local workers in order to jump the queue for vaccines that had been reserved for the elderly and vulnera
22h
Proceedings of the National Academy of Sciences current issue
A glycan FRET assay for detection and characterization of catalytic antibodies to the Cryptococcus neoformans capsule [Chemistry]
 
Classic antibody functions include opsonization, complement activation, and enhancement of cellular antimicrobial function. Antibodies can also have catalytic activity, although the contribution of catalysis to their biological functions has been more difficult to establish. With the ubiquity of catalytic antibodies against glycans virtually unknown, we sought to advance this knowledge….
23h
Proceedings of the National Academy of Sciences current issue
Adenovirus-vectored vaccine containing multidimensionally conserved parts of the HIV proteome is immunogenic in rhesus macaques [Biophysics and Computational Biology]
 
An effective vaccine that can protect against HIV infection does not exist. A major reason why a vaccine is not available is the high mutability of the virus, which enables it to evolve mutations that can evade human immune responses. This challenge is exacerbated by the ability of the virus…
23h
Futurity.org
Immune system may keep tabs on the brain from afar
 
Researchers may have figured out how the immune system keeps tabs on what's going on in the brain. Alzheimer's disease, multiple sclerosis, autism, schizophrenia, and many other neurological and psychiatric conditions have been linked to inflammation in the brain. There's growing evidence that immune cells and molecules play a key role in normal brain development and function as well. But at the
23h
ExtremeTechExtreme – ExtremeTech
Xiaomi Says Its New Product Can Charge a Phone From Across the Room
Xiaomi Mi Air Charge
•
 
Smartphone charging technology has improved dramatically in the last few years with some phones sucking down 65W of power or more. Xiaomi has been one of the companies to push both wired and wireless charging speeds, and now it says you don't need wires at all. The company's Mi Air Charge technology can allegedly charge your phone from a distance even while it's in your pocket. Or so Xiaomi claim
23h
EurekAlert! – Breaking News
Specific bacteria in the gut prompt mother mice to neglect their pups
 
As scientists learn more about the microorganisms that colonize the body–collectively called the microbiota–one area of intense interest is the effect that these microbes can have on the brain. A new study led by Salk Institute scientists has identified a strain of E. coli bacteria that, when living in the guts of female mice, causes them to neglect their offspring. The findings were published J
23h
Futurity.org
Mystery solved: What killed 9 hikers in Dyatlov Pass Incident?
 
New research offers a plausible explanation for the Dyatlov Pass Incident, the mysterious 1959 death of nine hikers in the Ural Mountains in what was then the Soviet Union. In early October 2019, when an unknown caller rang Johan Gaume's cell phone, he could hardly have imagined that he was about to confront one of the greatest mysteries in Soviet history. At the other end of the line, a journali
23h
Futurism
425 Megapixel Photo Shows Incredible Details on SpaceX Starship
 
Closer Look When you think of SpaceX's enormous Starship rocket, you probably imagine it looming far away in a landscape shot , or as a distant speck against the sky during a test flight. But a new photo by Ars Technica photographer Trevor Mahlmann shows the giant experimental spacecraft in astonishing, 425 megapixel detail — enough to make out a thicket of wires, welding scars, and even scribble
23h
EurekAlert! – Breaking News
Medicaid expansion in New York has improved maternal health, study finds
 
A new Columbia University study has found that Medicaid expansion in 2014 in New York State was associated with a statistically significant reduction in severe maternal morbidity in low-income women during delivery hospitalizations compared with high-income women. The decrease was even more pronounced in racial and ethnic minority women than in White women. Until now there was little research on t
23h
EurekAlert! – Breaking News
Dewdrops on a spiderweb reveal the physics behind cell structures
 
Researchers in the laboratories of Princeton University scientists Joshua Shaevitz, Howard Stone, and Sabine Petry have discovered that surface tension drives the liquid-like protein TPX2 to form globules that nucleate the formation of branching microtubules during cell division. The paper detailing these discoveries appeared in the Jan 28 issue of the journal Nature Physics .
23h
EurekAlert! – Breaking News
Genes that dance to the circadian rhythm
 
Scientists at EPFL have made breakthrough discoveries on the circadian clock and how it affects gene expression. Some of the findings suggest a biological underpinning for different behaviors in people, such as morning people, nappers, evening people, night owls etc.
23h
EurekAlert! – Breaking News
Our gut-brain connection
 
MIT researchers developed an 'organs-on-a-chip' system that replicates interactions between the brain, liver, and colon. They modeled the influence microbes living in the gut have on both healthy brain tissue and tissue samples derived from patients with Parkinson's disease.
23h
EurekAlert! – Breaking News
Accurate drug dosages with proton traps
 
Researchers at Linköping University, Sweden, have developed a proton trap that makes organic electronic ion pumps more precise when delivering drugs. The new technique may reduce drug side effects, and in the long term, ion pumps may help patients with symptoms of neurological diseases for which effective treatments are not available. The results have been published in Science Advances.
23h
Science Advances current issue
Amorphization in extreme deformation of the CrMnFeCoNi high-entropy alloy
 
Ever-harsher service conditions in the future will call for materials with increasing ability to undergo deformation without sustaining damage while retaining high strength. Prime candidates for these conditions are certain high-entropy alloys (HEAs), which have extraordinary work-hardening ability and toughness. By subjecting the equiatomic CrMnFeCoNi HEA to severe plastic deformation through sw
1d
Science Advances current issue
Gyroresonant wave-particle interactions with chorus waves during extreme depletions of plasma density in the Van Allen radiation belts
 
The Van Allen Probes mission provides unique measurements of the most energetic radiation belt electrons at ultrarelativistic energies. Simultaneous observations of plasma waves allow for the routine inference of total plasma number density, a parameter that is very difficult to measure directly. On the basis of long-term observations in 2015, we show that the underlying plasma density has a cont
1d
Science Advances current issue
Prototypical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer
 
Comprehensive genomic analyses of small cell lung cancer (SCLC) have revealed frequent mutually exclusive genomic amplification of MYC family members. Hence, it has been long suggested that they are functionally equivalent; however, more recently, their expression has been associated with specific neuroendocrine markers and distinct histopathology. Here, we explored a previously undescribed role
1d
Science Advances current issue
Extensive tissue-specific expression variation and novel regulators underlying circadian behavior
 
Natural genetic variation affects circadian rhythms across the evolutionary tree, but the underlying molecular mechanisms are poorly understood. We investigated population-level, molecular circadian clock variation by generating >700 tissue-specific transcriptomes of Drosophila melanogaster ( w 1118 ) and 141 Drosophila Genetic Reference Panel (DGRP) lines. This comprehensive circadian gene expre
1d
Science Advances current issue
Coherent control of collective nuclear quantum states via transient magnons
 
Ultrafast and precise control of quantum systems at x-ray energies involves photons with oscillation periods below 1 as. Coherent dynamic control of quantum systems at these energies is one of the major challenges in hard x-ray quantum optics. Here, we demonstrate that the phase of a quantum system embedded in a solid can be coherently controlled via a quasi-particle with subattosecond accuracy.
1d
Science Advances current issue
Tdp1 protects from topoisomerase 1-mediated chromosomal breaks in adult zebrafish but is dispensable during larval development
 
Deficiency in the DNA end-processing enzyme, tyrosyl-DNA phosphodiesterase 1 (TDP1), causes progressive neurodegeneration in humans. Here, we generated a tdp1 knockout zebrafish and confirmed the lack of TDP1 activity. In adulthood, homozygotes exhibit hypersensitivity to topoisomerase 1 (Top1) poisons and a very mild locomotion defect. Unexpectedly, embryonic tdp1 –/– zebrafish were not hypersen
1d
Science Advances current issue
Asymptotic turbulent friction in 2D rough-walled flows
 
The friction f is the property of wall-bounded flows that sets the pumping cost of a pipeline, the draining capacity of a river, and other variables of practical relevance. For highly turbulent rough-walled pipe flows, f depends solely on the roughness length scale r , and the f – r relation may be expressed by the Strickler empirical scaling f r 1/3 . Here, we show experimentally that for soap f
1d
Science Advances current issue
Radiation-induced eosinophils improve cytotoxic T lymphocyte recruitment and response to immunotherapy
 
The efficacy of cancer immunotherapy is dictated by CD8 + T cell infiltration and the nature of the tumor microenvironment (TME). By inflaming the TME to favor CD8 + T cell immunity, radiation is now widely considered as a neoadjuvant for immunomodulation. Here, we observed that local irradiation enhances the infiltration of intratumoral eosinophils, and depletion of eosinophil dampens CD8 + T ce
1d
Science Advances current issue
Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases
 
Slow progress in the fight against neurodegenerative diseases (NDs) motivates an urgent need for highly controlled in vitro systems to investigate organ-organ– and organ-immune–specific interactions relevant for disease pathophysiology. Of particular interest is the gut/microbiome-liver-brain axis for parsing out how genetic and environmental factors contribute to NDs. We have developed a mesoflu
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Science Advances current issue
Lewis acid-catalyzed domino generation/[2,3]-sigmatropic rearrangement of ammonium ylides to access chiral azabicycles
 
[2,3]-Sigmatropic rearrangement of ammonium ylides represents a fundamental reaction for stereoselective synthesis of nitrogenous compounds. However, its applicability is limited by the scarcity of efficient, catalytic, and mild methods for generating ammonium ylides. Here, we report silver-catalyzed domino generation/[2,3]-sigmatropic rearrangement of ammonium ylides, furnishing chiral azabicycl
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Science Advances current issue
Mechanism of C-type inactivation in the hERG potassium channel
 
The fast C-type inactivation displayed by the voltage-activated potassium channel hERG plays a critical role in the repolarization of cardiac cells, and malfunction caused by nonspecific binding of drugs or naturally occurring missense mutations affecting inactivation can lead to pathologies. Because of its impact on human health, understanding the molecular mechanism of C-type inactivation in hE
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Science Advances current issue
Adipose saturation reduces lipotoxic systemic inflammation and explains the obesity paradox
 
Obesity sometimes seems protective in disease. This obesity paradox is predominantly described in reports from the Western Hemisphere during acute illnesses. Since adipose triglyceride composition corresponds to long-term dietary patterns, we performed a meta-analysis modeling the effect of obesity on severity of acute pancreatitis, in the context of dietary patterns of the countries from which t
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Science Advances current issue
An electronic proton-trapping ion pump for selective drug delivery
 
The organic electronic ion pump (OEIP) delivers ions and charged drugs from a source electrolyte, through a charge-selective membrane, to a target electrolyte upon an electric bias. OEIPs have successfully delivered -aminobutyric acid (GABA), a neurotransmitter that reduces neuronal excitations, in vitro, and in brain tissue to terminate induced epileptic seizures. However, during pumping, proton
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Science Advances current issue
A 3D disease and regeneration model of peripheral nervous system-on-a-chip
 
Demyelinating diseases involve loss of myelin sheaths and eventually lead to neurological problems. Unfortunately, the precise mechanisms remain unknown, and there are no effective therapies. To overcome these limitations, a reliable and physiologically relevant in vitro model is required. Here, we present a three-dimensional peripheral nervous system (PNS) microfluidic platform that recapitulate
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Science Advances current issue
Keratinocytes control skin immune homeostasis through de novo-synthesized glucocorticoids
 
Glucocorticoids (GC), synthesized by the 11β-hydroxylase (Cyp11b1), control excessive inflammation through immunosuppressive actions. The skin was proposed to regulate homeostasis by autonomous GC production in keratinocytes. However, their immunosuppressive capacity and clinical relevance remain unexplored. Here, we demonstrate the potential of skin-derived GC and their role in the regulation of
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Science Advances current issue
Bandwidth-unlimited polarization-maintaining metasurfaces
 
Any arbitrary state of polarization of light beam can be decomposed into a linear superposition of two orthogonal oscillations, each of which has a specific amplitude of the electric field. The dispersive nature of diffractive and refractive optical components generally affects these amplitude responses over a small wavelength range, tumbling the light polarization properties. Although recent wor
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Science Advances current issue
Thermal squeezing of the seismogenic zone controlled rupture of the volcano-rooted Flores Thrust
 
Temperature plays a critical role in defining the seismogenic zone, the area of the crust where earthquakes most commonly occur; however, thermal controls on fault ruptures are rarely observed directly. We used a rapidly deployed seismic array to monitor an unusual earthquake cascade in 2018 at Lombok, Indonesia, during which two magnitude 6.9 earthquakes with surprisingly different rupture chara
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Science Advances current issue
Layer- and gate-tunable spin-orbit coupling in a high-mobility few-layer semiconductor
 
Spin-orbit coupling (SOC) is a relativistic effect, where an electron moving in an electric field experiences an effective magnetic field in its rest frame. In crystals without inversion symmetry, it lifts the spin degeneracy and leads to many magnetic, spintronic, and topological phenomena and applications. In bulk materials, SOC strength is a constant. Here, we demonstrate SOC and intrinsic spi
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Science Advances current issue
Improper molecular ferroelectrics with simultaneous ultrahigh pyroelectricity and figures of merit
 
Although ferroelectric materials exhibit large pyroelectric coefficients, their pyroelectric figures of merit (FOMs) are severely limited by their high dielectric constants because of the inverse relationship between FOMs and dielectric constant. Here, we report the molecular ferroelectric [Hdabco]ClO 4 and [Hdabco]BF 4 (dabco = diazabicyclo[2.2.2]octane) exhibiting improper ferroelectric behavio
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Science Advances current issue
Microbiota control of maternal behavior regulates early postnatal growth of offspring
 
Maternal behavior is necessary for optimal development and growth of offspring. The intestinal microbiota has emerged as a critical regulator of growth and development in the early postnatal period life. Here, we describe the identification of an intestinal Escherichia coli strain that is pathogenic to the maternal-offspring system during the early postnatal stage of life and results in growth st
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Science Advances current issue
SINGLE: Atomic-resolution structure identification of nanocrystals by graphene liquid cell EM
 
Analysis of the three-dimensional (3D) structures of nanocrystals with solution-phase transmission electron microscopy is beginning to reveal their unique physiochemical properties. We developed a "one-particle Brownian 3D reconstruction method" based on imaging of ensembles of colloidal nanocrystals using graphene liquid cell electron microscopy. Projection images of differently rotated nanocrys
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Science | The Guardian
'Immunological unicorn': the Australian lab growing coronavirus – and its startling discovery
 
Researchers walk through three negative-pressure chambers before entering the submarine-like structure In a high security laboratory in Sydney, where a select group of researchers go to extreme lengths to work with samples of blood and swabs containing Covid-19, virologist Stuart Turville found a unicorn. "A beautiful, immunological unicorn," Turville, an associate professor with the Kirby Instit
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Phys.org
Genes that dance to the circadian rhythm
 
Scientists at EPFL have made breakthrough discoveries on the circadian clock and how it affects gene expression. Some of the findings suggest a biological underpinning for different behaviors in people, such as morning people, nappers, evening people, night owls etc.
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Phys.org
Accurate drug dosages with proton traps
 
Researchers at Linköping University, Sweden, have developed a proton trap that makes organic electronic ion pumps more precise when delivering drugs. The new technique may reduce drug side effects, and in the long term, ion pumps may help patients with symptoms of neurological diseases for which effective treatments are not available. The results have been published in Science Advances.
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Futurism
Study: Catching Coronavirus Makes it Harder for Men to Have Kids
 
Just in case the coronavirus still wasn't ominous enough, now there's evidence that it's even capable of reducing male fertility and damaging sperm cells. It turns out that COVID-19 is capable of killing off sperm and causing inflammation in the testicles, potentially to disastrous ends as far as people's ability to reproduce is concerned, according to a new study published Friday in the journal
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ScienceDaily
Focusing on field analysis
 
One potential approach to developing a low-cost portable microscopy system is to use transparent microspheres in combination with affordable low-magnification objective lenses to increase image resolution and sensitivity.
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Futurity.org
World's most explosive volcano holds lots of water
 
A new study of Shiveluch, the most explosive volcano in the world, could help scientists understand more about the global water cycle and volcanic plumbing systems. Shiveluch volcano, located in Kamchatka, a remote peninsula in northeastern Russia just across the Bering Sea from Alaska, has had more than 40 violent eruptions over the last 10,000 years. The last gigantic blast occurred in 1964, cr
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Sciencemag
J&J and Novavax Data
 
Suddenly we have a lot more vaccine efficacy data to discuss! Yesterday came an announcement from Novavax about trials they've been conducting in the UK and in South Africa with their recombinant protein vaccine, and today comes equally anticipated data from J&J (Janssen) on their adenovirus vector candidate. We'll have a look at the numbers in that order. The full Novavax package should be comin
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ScienceDaily
Juicing technique could influence healthfulness of fresh-squeezed juice
 
With the New Year, many people are making resolutions to eat healthier, by eating more vegetables, for example. But those who don't like the taste or texture of some vegetables might prefer to drink them in a home-squeezed juice. Now, researchers have found that the choice of household juicing technique can influence the phytochemical content and antioxidant activity of common vegetable juices.
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Science | The Guardian
Lewis Wolpert obituary
 
Developmental biologist and science communicator with an enduring fascination for the beginnings of life How does a single fertilised egg divide and morph into an embryo with head, tail, limbs and organs? That question was an inexhaustible source of fascination to the biologist Lewis Wolpert, who has died aged 91. With a twinkle in his eye, he told audiences it was not birth, marriage or death, bu
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Science | The Guardian
UK vaccine strategy 'paying off' as latest trials boost stockpiles
 
Pre-ordering of Janssen and Novavax means Britain has procured 247m successfully trialled jabs Coronavirus – latest updates See all our coronavirus coverage Britain has cemented its status as one of the world's leading buyers of effective Covid vaccines after two more pharmaceutical companies reported positive trial results – potentially growing the UK stockpile by 90m doses. The US drugmaker Joh
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Popular Science | RSS
Brain size isn't everything
 
Ant brains are minuscule, yet they work together to build relatively enormous homes and coordinate hunts for food. (Glenn Orzepowski/) When we think, each of our brain cells fires signals to as many as 1,000 neighboring neurons up to 200 times per second. This enables complex decision-making like navigating a four-way stop or solving an algebra problem. But animals with tiny noggins (or none at a
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Biology News – Evolution, Cell theory, Gene theory, Microbiology, Biotechnology
Startup develops yeast-based COVID-19 diagnostic test
 
Incubated at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil, and supported by São Paulo Research Foundation- FAPESP's Innovative Research in Small Business Program (PIPE), BIOinFOOD is a startup that is developing a rapid COVID-19 diagnostic test based on a patent application filed by students at UNICAMP's Genomics and Bioenergy Laboratory.
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Phys.org
Startup develops yeast-based COVID-19 diagnostic test
 
Incubated at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil, and supported by São Paulo Research Foundation- FAPESP's Innovative Research in Small Business Program (PIPE), BIOinFOOD is a startup that is developing a rapid COVID-19 diagnostic test based on a patent application filed by students at UNICAMP's Genomics and Bioenergy Laboratory.
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Futurism
Google Deletes 100,000 Negative Robinhood Reviews
 
Positive Feedback Google has entered the fray of the Wall Street Bets fiasco by stepping in to salvage Robinhood's rating on the app store. The search giant stepped in after about 100,000 angry users flooded the stock trading app Robinhood with one-star reviews on Google's Play Store, according to The Verge . While it's not a shocking move — Google is well within its rights to curate app store re
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EurekAlert! – Breaking News
Americans like sports, but heterosexual men especially do
 
Nearly nine out of 10 Americans say they enjoy sports at least a little, but heterosexual men more commonly identify as passionate sports fans, a new study suggests. A survey of nearly 4,000 American adults found that only 11% said they did not identify as sports fans at all. Over 40% were passionate fans, identifying themselves as being "quite a bit" or "very much so" sports fans.
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EurekAlert! – Breaking News
Researchers use AI to help businesses understand Code of Federal Regs, other legal docs
 
Automated Legal Document Analytics (ALDA) provides tools for people, businesses, and other entities to understand highly complex, legally binding documents. Using AI, a UMBC team has now broken down the Code of Federal Regulations into components that are semantically linked for automated analysis. This means that any user can 'ask' the system whether something is allowable under the code, increas
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EurekAlert! – Breaking News
Robotic exoskeleton training expands options for stroke rehabilitation
 
Researchers are applying new technologies to gait training that may offer advantages over traditional labor intensive physical therapy. This inpatient study of a robotic exoskeleton (Ekso GT, Ekso Bionics, Inc,) demonstrated the potential to improve gait training after acute stroke toward the goal of earlier recovery of motor function. "We found that gait training in the exoskeleton allowed us to
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Phys.org
How is human behavior impacting wildlife movement?
 
For species to survive in the wild, maintaining connectivity between populations is critical. Without 'wildlife corridors,' groups of animals are isolated, unable to breed and may die out. In assessing wildlife connectivity, many aspects of the landscape are measured, but the impact of human behavior has largely been overlooked. Now, an international team led by the University of Göttingen and Hum
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Phys.org
Coiling them up: Synthesizing organic molecules with a long helical structure
 
Scientists at Tokyo Institute of Technology (Tokyo Tech) produced and extensively characterized novel organic molecules with a long helical structure. Unlike previous helical molecules, these longer compounds exhibit special interactions between coils that could give rise to interesting optical and chemical properties with applications in light polarization, catalysis, and molecular springs.
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Biology News – Evolution, Cell theory, Gene theory, Microbiology, Biotechnology
How is human behavior impacting wildlife movement?
 
For species to survive in the wild, maintaining connectivity between populations is critical. Without 'wildlife corridors,' groups of animals are isolated, unable to breed and may die out. In assessing wildlife connectivity, many aspects of the landscape are measured, but the impact of human behavior has largely been overlooked. Now, an international team led by the University of Göttingen and Hum
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Big Think
Monkeys are capable of inferential reasoning, study shows
 
For centuries, humans have wondered which cognitive abilities animals share with people. In a new study, researchers presented baboons with a "hidden-item" task designed to test their understanding of disjunctive syllogisms. The results showed that the baboons were not only successful in the task, but also displayed signs of confidence in their decision making. You show a toddler a treat. Out of
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Phys.org
New psychological model predicts who panic-buys during times of crisis
 
Drawing on animal-foraging theory, a new model predicts psychological factors that may lead to panic buying during times of crisis. The model is largely supported by real-world data from the COVID-19 pandemic. Richard Bentall of the University of Sheffield, England, and colleagues presented these findings in the open-access journal PLOS ONE on January 27.
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Science | The Guardian
WHO Covid study team makes first site visit to Wuhan hospital
 
World Health Organization experts conduct on-the-ground research into origins of pandemic in China Coronavirus – latest updates See all our coronavirus coverage An international team of World Health Organization experts has visited a hospital in Wuhan, China, that saw some of the first cases of Covid in December 2019, as part of an on-the-ground investigation into the origins of the virus that ca
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Futurism
Elon Musk Doubles Down on Wall Street Bets: "Shorting Is a Scam"
 
Stonk Honk SpaceX and Tesla CEO Elon Musk took a break from feuding with the FAA yesterday afternoon to weigh in again on the ongoing Wall Street Bets saga , writing that "shorting is a scam" which is, in his opinion, " legal only for vestigial reasons ." His entire tweet is written in a middle school-esque patois — here's the raw version: Short History This isn't the first time Musk has waded in
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EurekAlert! – Breaking News
How is human behavior impacting wildlife movement?
 
For species to survive in the wild, maintaining connectivity between populations is critical. Without 'wildlife corridors', groups of animals are isolated and may die out. In assessing wildlife connectivity, many aspects of the landscape are measured, but the impact of human behaviour has largely been overlooked. Now, an international team led by the University of Göttingen and Humboldt University
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EurekAlert! – Breaking News
How coronavirus damages lung cells within mere hours
 
Boston University team has revealed the most comprehensive map to date of all the molecular activities that are triggered inside lung cells at the onset of coronavirus infection. They also discovered there are at least 18 existing, FDA-approved drugs that could potentially be repurposed to combat COVID-19 infections shortly after a person becomes infected.
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Climate Central – News
Climate Change Threatens Homes of Boston's Most Vulnerable
 
By Ayurella Horn-Muller (Climate Central) and Christopher Gloninger (NBC Boston) and Ale Zimmermann (NBC Boston) contributed reporting In East Boston, affordable housing units are at risk of flooding as the sea level rises. This video and text story was produced through a collaboration with NBC Boston. Roxanne De Jesus remembers seeing the waves spill out of the harbor in East Boston. A nor'easte
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The Atlantic
A Brilliant Horror Film That Twists Faith Into Fear
 
"When you pray, do you get a response?" A terminally ill cancer patient named Amanda (played by Jennifer Ehle) poses this innocent-sounding but loaded question to her nurse, Maud (Morfydd Clark). Amanda knows that Maud is religious and says her nightly prayers, but Maud reveals that her devotion to God runs even deeper. "Sometimes he talks," the nurse replies. "Most of the time it's just like he'
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Phys.org
Researchers demonstrate how to measure student attention during remote learning
 
The COVID-19 pandemic has made home offices, virtual meetings and remote learning the norm, and it is likely here to stay. But are people paying attention in online meetings? Are students paying attention in virtual classrooms? Researchers Jens Madsen and Lucas C. Parra from City College of New York, demonstrate how eye tracking can be used to measure the level of attention online using standard w
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Phys.org
Local emissions amplify regional haze and particle growth
 
New particle formation (NPF) is a major source of aerosol particles in the global atmosphere. In polluted megacities, such as Beijing, the role of new particle formation events and their contribution to haze formation through subsequent growth is still unclear.
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Phys.org
High-speed holographic fluorescence microscopy system with submicron resolution
 
The National Institute of Information and Communications Technology (NICT), Tohoku University, Toin University of Yokohama, and Japan Science and Technology Agency (JST) have succeeded in developing a scanless high-speed holographic fluorescence microscopy system with submicron resolution for a 3-D space. The system is based on digital holography.
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Phys.org
Yangtze River observational system to improve East Asian rainy season forecasting
 
Researchers have completed the first ever multi-level hydrological tracking of the Yangtze River from the ground, air and space in order to investigate the properties of cloud formation during the mei-yu—an intense rainy season that forms part of East Asia's summer monsoon. The effort should permit greater understanding of the mei-yu precipitation process and thus enable much more accurate forecas
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Phys.org
New technology to detect bitter almonds in real time
 
Who hasn't at some point been chewing on an almond and tasted an unpleasant and unexpected aftertaste that has nothing to do with the taste we are used to from one of the most consumed nuts in the world? The culprit has a name: amygdalin, a diglucoside that, when in contact with enzymes present in saliva, breaks down into glucose, benzaldehyde (the cause of the bitter taste) and hydrogen cyanide.
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EurekAlert! – Breaking News
Scientists identify locations of early prion protein deposition in retina
 
The earliest eye damage from prion disease takes place in the cone photoreceptor cells, specifically in the cilia and the ribbon synapses, according to a new study of prion protein accumulation in the eye by National Institutes of Health scientists. Prion diseases originate when normally harmless prion protein molecules become abnormal and gather in clusters and filaments in the human body and bra
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EurekAlert! – Breaking News
Researchers illustrate the need for anti-racism in kidney care, research
 
There is a growing awareness of systematic inequality and structural racism in American society. Science and medicine are no exception, as evidenced by historical instances of discrimination and overt racism. In a perspective piece in the Journal of the American Society of Nephrology, researchers from Boston University School of Medicine (BUSM), take an honest look at how the current practice of n
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EurekAlert! – Breaking News
Singles or pairs in cancer cells
 
An important receptor on the surface of cancer and immune cells prefers to remain noncommittal; sometimes it is present as a single, sometimes as a pair. This was first shown by an MDC team in the journal PNAS, and will decisively advance the development of new medications.
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EurekAlert! – Breaking News
Childhood trauma could affect development, treatment of multiple sclerosis
 
Childhood trauma could affect the trajectory of multiple sclerosis development and response to treatment in adulthood, a new study in mice found. Mice that had experienced stress when young were more likely to develop the autoimmune disorder and less likely to respond to a common treatment, researchers at the University of Illinois Urbana-Champaign found. However, treatment that activated an immun
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MIT Technology Review
An AI saw a cropped photo of AOC. It autocompleted her wearing a bikini.
 
Language-generation algorithms are known to embed racist and sexist ideas. They're trained on the language of the internet, including the dark corners of Reddit and Twitter that may include hate speech and disinformation. Whatever harmful ideas are present in those forums get normalized as part of their learning. Researchers have now demonstrated that the same can be true for image-generation alg
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Undark Magazine
Despite Ramp Up, Vaccine Rollout Remains Patchy
 
The pace of Covid-19 vaccination continued to accelerate in the U.S. this week, with health care workers now delivering around 1.2 million shots each day. Still, distribution remains patchy, with some states lagging and a disproportionate share of shots going to White patients.
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Futurity.org
Malaria led to speedy evolution on island off African coast
 
Researchers have uncovered recent traces of adaptation to malaria in the DNA of people from Cabo Verde, an island nation off the African coast. An archipelago of 10 islands in the Atlantic Ocean some 385 miles offshore from Senegal, Cabo Verde was uninhabited until the mid-1400s, when it was colonized by Portuguese sailors who brought enslaved Africans with them and forced them to work the land.
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The Atlantic
A Group of Orca Outcasts Is Now Dominating an Entire Sea
 
On a warm September afternoon, on San Juan Island off the northwestern coast of Washington State, I boarded J2, a sleek black-and-white whale-watching vessel. The boat was named after a locally famous orca, or killer whale, affectionately known as "Granny." Until her disappearance in 2016, Granny was the matriarch of J-pod, one of the three resident orca groups, or pods, that live in the surround
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The Atlantic
The Simple Task That Mars Made Impossible
 
Troy Hudson didn't want to think about Mars. It was Christmas, he had taken some time off, and this planet had enough going on at the end of 2020. But Mars was difficult to escape, he told me. It twirled in a mobile of the solar system in his home. It sat right there on his skin, tattooed on his arm, below the elbow. Hudson had spent more than a decade working on a robot that was currently parked
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Big Think
How to close the digital gap for the elderly
 
Many young people have embraced the convenience of digital technologies such as online shopping, car hailing, digital payments, and telemedicine. But many elderly without a grasp of the latest knowledge are at risk of being left behind. Several news reports in China during the outbreak of COVID-19 put this issue in the spotlight: an elderly woman who wanted to pay for her medical insurance with c
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EurekAlert! – Breaking News
Scientists spotted RPS-12 protein as a potential target for anti-cancer therapy
 
Using the developing eye of the fruit fly as a test platform, researchers found that RPS-12 protein overproduction appears to trigger triple-negative breast cancer and possibly some other malignancies. The protein indirectly switches on an important inracellular signaling pathway active while the embryo develops and shut down in healthy cells of adults. Far Eastern Federal University (FEFU), the U
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EurekAlert! – Breaking News
Football and inclusion: It all comes down to the right motivational climate
 
Playing football has the potential to promote the inclusion of young people who are not from the predominant culture of a country, i.e. young migrants. Crucially, the feeling of belonging and being accepted depends on the trainer's approach to training – or more precisely, the motivational climate they create. Task-oriented training is significantly more suitable than training that is geared towar
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EurekAlert! – Breaking News
How vitamins, steroids and potential antivirals might affect SARS-CoV-2
 
Evidence is emerging that vitamin D — and possibly vitamins K and A — might help combat COVID-19. A new study from the University of Bristol published in the journal of the German Chemical Society Angewandte Chemie has shown how they – and other antiviral drugs — might work. The research indicates that these dietary supplements and compounds could bind to the viral spike protein and so might re
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EurekAlert! – Breaking News
Assessment of maternal, neonatal cord blood SARS-CoV-2 antibodies, placental transfer ratios
 
Maternally derived antibodies are a key element of neonatal immunity. This study examined the association between maternal and neonatal SARS-CoV-2-specific antibody concentrations because understanding the dynamics of maternal antibody responses to SARS-CoV-2 infection during pregnancy and subsequent transplacental antibody transfer can inform neonatal management as well as maternal vaccination st
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EurekAlert! – Breaking News
County by county, study shows social inequality's role in COVID-19's toll
 
A new study shows just how unevenly COVID-19 cases and deaths have played out across the country. It finds that the more disadvantaged a county's population was before the pandemic, the higher the toll of coronavirus last spring and summer. That level of disadvantage, measured on a standard scale called the Social Vulnerability Index (SVI), tracked closely with the number of cases and deaths per 1
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EurekAlert! – Breaking News
A potentially safer, more effective gene therapy vector for blood disorders
 
Researchers at Children's Hospital of Philadelphia (CHOP) have developed a gene therapy vector for blood disorders like sickle cell disease and beta-thalassemia that is potentially safer and more effective than those currently used in gene therapy trials for those conditions. The vector, an engineered vehicle for delivering functional copies of the hemoglobin gene to correct a genetic abnormality,
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Ingeniøren
Forskere afslører mysterium om træers vækst
 
Med en genteknologisk metode er det nu for første gang muligt at se ind i planters byggeproces. Den nye forskning i planters cellevægge udført af blandt andre Københavns Universitet åbner op for at skabe stærkere byggematerialer og mere klimaeffektive træer.
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Futurity.org
Brain connectivity reveals ADHD in kids with 99% accuracy
 
Specific communication among different brain regions, known as brain connectivity, can serve as a biomarker for ADHD, according to a new study. The research relied on a deep architecture using machine-learning classifiers to identify with 99% accuracy those adults who had received a childhood diagnosis of attention deficit hyperactivity disorder (ADHD) many years earlier. "It's by far the highest
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Futurism
FAA Grounds Starship SN9 Again, But SpaceX Rolls Out SN10 Instead
 
Ground Control Yesterday afternoon, SpaceX's strange standoff with the FAA — in which it continued to fuel its experimental Starship spacecraft even after the regulatory agency scrubbed the launch — ended in an apparent d étente when SpaceX stood down without incident. The plan was to launch Starship today instead, but the FAA nixed that plan early this morning. "We will continue working with Spa
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ScienceDaily
Scientists discover a new promising target for diabetes treatment
 
Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The blocking of inceptor function leads to an increased sensitisation of the insulin signaling pathway in pancreatic beta cells. This might allow protection and regeneration of beta cells for diabetes remission.
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ScienceDaily
Efficient formation of amide bonds under mild conditions
 
Linking molecular components through amide bonds is one of the most important reactions in research and the chemical industry. Scientists have now introduced a new type of reaction for making amide bonds. Called an ASHA ligation, this reaction is fast, efficient, works under mild aqueous conditions, and is broadly applicable.
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Big Think
On acceptance: Clichés vs. viscosity
 
It's good to be able to accept what there is. And although one does not need to apply this skill always or without moderation, it is one of the most important exercises for the human spirit. There is a playful summary of the history of philosophy – written, I think, by Leszek Kołakowski – where every philosopher is given one fourth of a sentence. "Aristotle: stick to the Middle state between, you
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Popular Science | RSS
Best baby monitor: How to find the right one for your family
 
Keep an eye on your child no matter what room you're in. (Tuva Mathilde Løland via Unsplash/) People sometimes complain that modern moms and dads are too nervous and overprotective, and that "back in our day," parenting was a more relaxed and hands-off endeavor. But anyone with a newborn knows that the early days are a time of incredible joy…and intense neuroses. And if those supposedly "lax" p
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EurekAlert! – Breaking News
Novel therapy-resistance mechanism promoting the growth of breast cancer brain metastasis
 
SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells. Professor Johanna Ivaska's research group at Turku Bioscience observed that SORLA functionally contributes to the most reported therapy-resistant mechanism by which the cell-surface receptor HER3 counteracts HER2 targeting therapy in HER2-positive cancers. Removing SORLA from
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TED Talks Daily (SD video)
What a cactus taught me about prickly emotions | Jessica Woods
 
Difficult emotions are like the spikes of a cactus: they can get under your skin if you're not careful. In this empowering talk, performance psychologist Jessica Woods shares four mood-regulating strategies to help you gain self-awareness of your feelings, avoid catching other people's emotions and perform at your peak — whatever the prickly situation may be.
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Futurism
The Single Shot Vaccine Is Far Less Effective, But Still Pretty Good
 
Pharma giant Johnson & Johnson finally shared data on how well its single-injection coronavirus vaccine works, and while it seems to clear the bar for FDA approval, it didn't blow experts out of the water like Moderna and Pfizer's vaccines did. Overall, the vaccine was 85 percent effective at preventing severe cases of COVID-19, The Washington Post reports , and Johnson & Johnson says that its va
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The Atlantic
The Books Briefing: 5 Short Stories to Read This Weekend
 
I often think of fiction as fact's partner in the pursuit of truth. At its best, the genre is capable of rendering the worlds we're unable to imagine, and also of revealing the ones hidden around us. Last year, The Atlantic recommitted itself to publishing fiction with greater frequency. Short stories continue to thrive alongside our important journalistic efforts, and we have begun 2021 intent o
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Science | The Guardian
Oxford/AstraZeneca Covid vaccine given full approval by EU regulator
 
European Medicines Agency approves jab for use in all age groups above 18, despite German doubts Coronavirus – latest updates See all our coronavirus coverage The European Medicines Agency has authorised the Oxford/AstraZeneca Covid-19 vaccine for use in all adult age groups after days of doubt. A month after it received approval in the UK , the EU's regulator declared the vaccine safe for genera
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Popular Science | RSS
COVID-19 vaccines could end the pandemic by eliminating severe cases
 
As the vaccine distribution ramps up over the next few months, there should be another boon: a huge drop in the occurrence of severe COVID-19. (Pixabay /) The Biden administration announced this week that it will purchase an additional 200 million doses of the COVID-19 vaccines from Pfizer and Moderna, which means the United States will have enough vaccine doses to immunize 300 million people (ne
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EurekAlert! – Breaking News
Local emissions amplify regional haze and particle growth
 
A Finnish-Chinese research team performed simultaneous measurements of aerosol composition and particle number size distributions at ground level and at 260 m in central Beijing, China, during a total of 4 months in 2015-2017. The team found concentration of both primary and secondary particles in the accumulation mode would decrease drastically, and the haze formation would be reduced if the emis
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EurekAlert! – Breaking News
Biobased anti-thrombosis agent
 
Thrombosis, the clogging of blood vessels, is a major cause of heart attacks and embolism. Scientists have now engineered the first inhibitors of thrombin, a protease promoting thrombosis, that is three-fold efficient. In a study published in the journal Angewandte Chemie, the authors demonstrate that attacking three sites of the thrombin molecule is more efficient than attacking only two sites, w
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EurekAlert! – Breaking News
High-speed holographic fluorescence microscopy system with submicron resolution
 
The National Institute of Information and Communications Technology (NICT), Tohoku University, Toin University of Yokohama, and Japan Science and Technology Agency (JST) have succeeded in developing a scanless high-speed holographic fluorescence microscopy system with submicron resolution for a 3D space. The system is based on digital holography. The developed microscopy system has an algorithm to
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