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Non-immune cells make 'detergent' to clean out pathogens
Researchers have found a particularly powerful weapon for fighting infection in non-immune system cells' arsenal—a protein that acts like a detergent to wipe out invading pathogens. This intracellular cleanser works much like the way that Ajax cleans dirty dishes or sanitizes a kitchen countertop. It dissolves membranes of invading bacteria that have replicated in the cytosol , the watery interio
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Wildfire smoke in New England is 'pretty severe from public health perspective'
On Monday, the air quality in Boston and the greater New England area was so bad that it was only rivaled by the areas in Northern California and Oregon currently on fire. An interactive map from the National Oceanic and Atmospheric Administration showed how smoke from the wildfires out west were being carried across the continental US by winds and the jet stream. In response to the blanket of smo
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Evidence and theory for lower rates of depression in larger US urban areas [Psychological and Cognitive Sciences]
It is commonly assumed that cities are detrimental to mental health. However, the evidence remains inconsistent and at most, makes the case for differences between rural and urban environments as a whole. Here, we propose a model of depression driven by an individual's accumulated experience mediated by social networks. The…
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Scientists discover early signs of frontotemporal dementia in personalized cerebral organoids
Frontotemporal dementias are a group of fatal and debilitating brain disorders for which there are no cures. Researchers describe how they were able to recreate much of the damage seen in a widely studied form of the disease by growing special types of cerebral organoids in petri dishes. This form of the disease is caused by a genetic mutation in tau, a protein that is a hallmark of Alzheimer's di
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New breakthrough to help immune systems in the fight against cancer
New research has identified potential treatment that could improve the human immune system's ability to search out and destroy cancer cells within the body. Scientists have identified a way to restrict the activity of a group of cells which regulate the immune system, which in turn can unleash other immune cells to attack tumours in cancer patients.
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Let's face the liquid-liquid interface
The demand for energy consumption, limited availability of fossil fuels, and pollution caused by the energy production industry challenge scientists to find new, more cost-effective, and greener solutions to produce power. Most of the current energy sources are far from being environmentally friendly. In this context, electrochemically assisted generation of chemicals, at first glance, would not b
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On the hunt for 'hierarchical' black holes
Black holes, detected by their gravitational wave signal as they collide with other black holes, could be the product of much earlier parent collisions. Such an event has only been hinted at so far, but scientists believe we are getting close to tracking down the first of these so-called 'hierarchical' black holes.
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COVID-19 survivors have broad, longer-term immunity
People who have recovered from COVID-19 retain broad and effective longer-term immunity to the disease, according to a new study. Findings of the study, which is the most comprehensive of its kind so far, have implications for expanding understanding about human immune memory as well as future vaccine development for coronaviruses. For the longitudinal study in Cell Reports Medicine , researchers
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A New Small Molecule Candidate for Malaria
Here's a new paper with a surprise: a small molecule that appears to be very effective against malaria, with what may be a high barrier to developing resistance ( C&E News coverage here ). It's from a large multicenter (multicontinent) team, and the chemical matter has its origins at Sanofi. The idea was to search for human homologs of targets that are present in several human blood-borne parasit
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Trying to 'feel younger' may not make you feel better
The disconnect between how old we feel and how old we want to be can offer insights into the relationship between our views on aging and our health, according to a new study. Subjective age discordance (SAD)—the difference between how old you feel and how old you would like to be—is a fairly new concept in the psychology of aging . However, the work to this point has used SAD to look at longitudi
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Will Olympic athletes perform worse without fans in the stands?
The 2020 Summer Olympics in Tokyo have had one notable absence: spectators. The decision to go on with the Games but to forbid fans was announced by organizers earlier this month as a resurgence of COVID-19 prompted Japan to declare a state of emergency in the capital city. The 11th hour shift in policy will deny Tokyo the colorful fanfare typically seen in Olympic host cities and cost organizers
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Online science and math resources for teachers of young children
As COVID-19 restrictions begin to ease and people return to the workplace this fall, many young children will return to child care centers, preschools and family child care homes. The University of Illinois Chicago's College of Education is reminding caregivers that they have available free online resources for both early math and early science education.
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How political nostalgia predicts political outcomes
Nostalgia, defined as a sentimental longing or wistful affection for the past, has become a growing focus of research in personality and social psychology. Though it may seem counterintuitive, nostalgia has been proven to be a great motivator of future behavior. Take for example, fans of former President Barack Obama. When the 2016 election of President Donald Trump left over half of the United St
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How Apple and Nike have branded your brain
Effective branding can not only change how you feel about a company, it can actually change how your brain is wired. Our new series "Your Brain on Money," created in partnership with Million Stories, recently explored the surprising ways brands can affect our behavior. Brands aren't going away. But you can make smarter decisions by slowing down and asking yourself why you're making a particular p
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The growing carbon footprint of streaming media
When was the last time you watched a DVD? If you're like most people, your DVD collection has been gathering dust as you stream movies and TV from a variety of on-demand services. But have you ever considered the impact of streaming video on the environment?
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Big Chief vs Patrick Thompson | Street Outlaws: Memphis
Stream Street Outlaws: Memphis on discovery+ ► https://www.discoveryplus.com/show/street-outlaws-memphis About Street Outlaws: Memphis: Street Outlaws is traveling to the toughest, meanest and wildest streets in the South, as it heads to Memphis to spotlight JJ Da Boss and his team of family and friends who have been racing together for decades. Subscribe to Discovery: http://bit.ly/SubscribeDisc
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Leader effectiveness may depend on emotional expression
Women leaders must often battle sexist stereotypes that label them 'too emotional' for effective leadership. A surprising new study shows that when they express calm, happy emotions, however, women are perceived as more effective leaders than men. The effect is most pronounced for leaders in top positions in an organization.
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Cultural biases impact native fish, too
From art to religion to land use, much of what is deemed valuable in the United States was shaped centuries ago by the white male perspective. Fish, it turns out, are no exception. A study explores how colonialist attitudes toward native fishes were rooted in elements of racism and sexism. It describes how those attitudes continue to shape fisheries management today, often to the detriment of nati
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The radical, revolutionary resilience of Black joy | Miracle Jones
In the face of trauma, happiness is resilience: a revolutionary act of thriving despite all odds, rather than wilting or surrendering. Community organizer and activist Miracle Jones offers a heart-to-heart meditation on the role of joy as a form of radical resistance, survival and protection for Black folks in the US and across the world. A warm reminder to embrace the guiding light of hope in the
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Ensuring sea turtles in rehab get a proper diet
Loggerhead sea turtles (Caretta caretta) are opportunistic carnivores that primarily feed on invertebrates and fish. In the wild, they eat a variety of food items depending on their life stage and geographic location. For debilitated sea turtles in rehabilitation, part of the healing process is to provide a species-specific, balanced diet that provides nutrition similar to that of a wild diet to a
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CT scans of shark intestines find Nikola Tesla's one-way valve
For the first time, scientists developed 3D scans of shark intestines to learn how they digest what they eat. The scans reveal an intestinal structure that looks awfully familiar — it looks like a Tesla valve. The structure may allow sharks to better survive long breaks between feasts. Considering how much sharks are feared by humans, it is a bit of a surprise that scientists don't know much abou
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Trust in science can be risky without critical mindset
People who trust science are more likely to believe and disseminate false claims that contain scientific references than are people who don't trust science, a study finds. Reminding people of the value of critical evaluation reduces belief in false claims, but reminding them of the value of trusting science does not. "The critical mindset makes you less gullible." "We conclude that trust in scien
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Animals are better sprinters than humans
An interdisciplinary group of scientists from the universities of Cologne, Koblenz, Tübingen, and Stuttgart has studied the characteristics determining the maximum running speed in animals. The model they developed explains why humans cannot keep up with the fastest sprinters in the animal kingdom. Based on these calculations, the giant spider Shelob from "The Lord of the Rings" would have reached
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Genomic secrets of gutless deep-sea tubeworm unlocked
Researchers from The Hong Kong University of Science and Technology (HKUST) decoded for the first time the chromosomal-level genome of a deep-sea gutless tubeworm and how the worm's co-living bacterial partners manufacture organic nutrients for its host so it can survive the extreme habitat. The discovery lays foundation for potential applications such as biomaterial production and microbial growt
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Elite runners stay in the air more than non-elites
A recent study compares the "bouncing behavior"—the underlying spring-like physics of running—in elite-level male runners (sub-four-minute milers) vs. highly trained but not elite runners. Subjects ran on a treadmill instrumented with a pressure plate beneath the belt, so the researchers could see how much time they spent in the air and in contact with the ground. When running, muscles and limbs
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Upcycling plastic waste into high-performing mechanical lubricants
Finding new solutions to address the challenges posed by plastic waste can dramatically improve global sustainability practices and help achieve a greener future. While many researchers are working to solve this problem on an international scale, a new, multi-institutional team is seeking to turn that waste into a high-performing contributor.
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Returning nitrogen to soils without chemicals
While agricultural production around the world struggles with declining soil health, Australian researchers are investigating production of a sustainable organic nitrogen fertilizer made from aquatic cyanobacterial biomass—ideally suited for badly degraded areas reliant on chemical fertilizers.
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Snow can disappear straight into the atmosphere in hot, dry weather
Creeks, rivers and lakes that are fed by melting snow across the U.S. West are already running low as of mid-July 2021, much to the worry of farmers, biologists and snow hydrologists like me. This is not surprising in California, where snow levels over the previous winter were well below normal. But it is also true across Colorado and the Rocky Mountains, which in general received a normal amount
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How health care providers can talk about guns
New guidelines educate health care professionals about how to help prevent firearm injuries. Each year, approximately 40,000 people in the United States die because of guns, making firearm-related injuries a leading cause of death for adults and children . According to a recent report , gun violence surged during the COVID-19 pandemic, making 2020 one of the nation's deadliest years for firearm-r
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A wet winter, a soggy spring: The negative Indian Ocean Dipole
This month we've seen some crazy, devastating weather. Perth recorded its wettest July in decades, with 18 straight days of relentless rain. Overseas, parts of Europe and China have endured extensive flooding, with hundreds of lives lost and hundreds of thousands of people evacuated.
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Her er hvad vi kan forvente af den nye store FN-klimarapport
PLUS. Om få uger lander første del af FN's klimapanels nye store hovedrapport, der er den sjette i rækken, som opsummerer de videnskabelige aspekter af klimasystemet og klimaforandringer. Mere fokus på ekstremt vejr og opdelinger i regioner er to nye centrale elementer. Nu indledes det politiske slagsm…
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Treating Brain Cancer with Magnets
Magnets for healing have a bad rap, one they rightfully deserve . Magnetic snake-oil devices with all sorts of bogus medical claims are as old as magnets themselves. It may have something to do with the fact that magnets seem like magic, exerting and invisible force at a distance. So it's often an easy sell. Also, magnets are real and do produce a real energy field (unlike the non-existent "life
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More Nigerian banks are using chatbots to serve customers, with mixed results
Chatbots are becoming an integral part of service provision around the world. Chatbots are computer programs designed to simulate a conversation—both voice and text—with human users, especially over the internet. They are described as a never-sleeping, cost-efficient and powerful way to provide basic support to consumers. Chatbots can respond faster to customers and even personalize consumer exper
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Achieve Mindfulness With A Lifetime Subscription To Mindabout
Meditation and mindfulness are useful ways to step back from your problems, get a handle on your anxiety, and even reshape how you think . Yet for those with a packed day, it can be intimidating to find a few minutes to even start. Mindabout was designed to help you surmount those obstacles. It typically lists for $399, and is on sale now for 90% off at just $39.99. Mindfulness In Your Pocket Min
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What Happens When You Need the Same Chips as the Major Automakers?
The semiconductor chip shortage has drawn significant attention, and for good reason. Simply put, a growing list of products on the market today are dependent on chipsets to offer key differentiators. Unfortunately, the demand for chips does not seem to be waning – quite the opposite in fact. For instance, global tech market advisory firm ABI Research finds other key users for chipsets, the consu
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Will Genetically Engineered Humans Matter in the Face of Cybernetic Humans?
My question regards primarily to the capabilities of biologically engineered humans as compared to those who undergo cybernetic enhancement. For instance, do you foresee biologically enhanced intelligence even mattering if we were all to have symbiotic AI's hooked up to our brains? For instance, imagine for a second that you could have the memory of a computer: you'd literally be able to store mi
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Correlative 3D microscopy of single cells using super-resolution and scanning ion-conductance microscopy
Nature Communications, Published online: 27 July 2021; doi:10.1038/s41467-021-24901-3 Methods for imaging the 3D cell surface often require physical interaction. Here the authors report the combination of scanning ion conductance microscopy (SICM) and live-cell super-resolution optical fluctuation imaging (SOFI) for the non-invasive topographical imaging of soft biological samples.
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Field-free spin-orbit torque-induced switching of perpendicular magnetization in a ferrimagnetic layer with a vertical composition gradient
Nature Communications, Published online: 27 July 2021; doi:10.1038/s41467-021-24854-7 Switching of ferrimagnets by current-induced spin-orbit torque is promising for spintronics, due to their high-speed dynamics and small macroscopic magnetization. Switching of perpendicularly magnetized materials, however, requires a bias field for symmetry breaking. Here, Zheng et al demonstrate field-free curr
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The upstream 5′ splice site remains associated to the transcription machinery during intron synthesis
Nature Communications, Published online: 27 July 2021; doi:10.1038/s41467-021-24774-6 We know that most splicing reactions take place co-transcriptionally, but how the transcription machinery facilitate splicing of introns is unknown. Here the authors show that the 5′ splice site remains associated with the transcription machinery during intron synthesis through U1 snRNP, providing a basis for th
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Individual environmental niches in mobile organisms
Nature Communications, Published online: 27 July 2021; doi:10.1038/s41467-021-24826-x Understanding how individual niches vary can inform ecology and conservation. A study of 45 GPS-tracked white storks across three breeding populations reveals that individual environmental niches are nested, arranged along a specialist-generalist gradient that is highly consistent over time.
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The trans-omics landscape of COVID-19
Nature Communications, Published online: 27 July 2021; doi:10.1038/s41467-021-24482-1 COVID-19 is a critical public health threat, but molecular characterizations of patients' immunity is still lacking. Here the authors collected blood from patients with various disease severity, and prefiltered to exclude selected comorbidity, to obtain genomic, transcriptomic, proteomic, metabolomic and lipidom
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Imparting multi-functionality to covalent organic framework nanoparticles by the dual-ligand assistant encapsulation strategy
Nature Communications, Published online: 27 July 2021; doi:10.1038/s41467-021-24838-7 Despite many reports on nanoparticle-covalent organic frameworks (COF) composites, a universal strategy for the synthesis of monodisperse core-shell structured COF nanocomposites remains challenging. Here, the authors develop a strategy for interfacial growth of highly crystalline COFs on functional nanoparticle
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Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis
Nature Communications, Published online: 27 July 2021; doi:10.1038/s41467-021-24876-1 BRAF-MAPK activating mutations are reported in histiocytoses—hematological neoplasms with widespread pro-inflammatory myeloid cells. Here, the authors show that an activating mutant BRAF in haematopoietic stem and progenitor cells causes an oncogene-induced senescence response leading to myeloid restricted haema
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Proposed NIH windfall raises hopes — and fears
Nature, Published online: 27 July 2021; doi:10.1038/d41586-021-02064-x Large increases to the budget of the US National Institutes of Health can spur wide investment, but also increase competition among junior researchers.
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Danske forskere: IoT-data kan invadere privatlivet
IoT-sensorer kan bruges til at indsamle oplysninger om eksempelvis elforbrug og luftkvalitet i et lokale, men ud fra disse simple data kan privatlivsinvaderende informationer også udledes. Det tænker man bare ikke på, lyder det fra ph.d.-studerende og professor ved SDU Software Engineering.
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Sporting super spikes: how do they work? – podcast
In the lead-up to the athletics competitions at the Tokyo Olympic Games 2020, Shivani Dave takes look at how advances in running shoe technology are resulting in records being smashed. Talking to Geoff Burns, a postdoctoral research fellow at the University of Michigan who specialises in biomechanics, Shivani asks how so-called 'super spikes' work and if the mechanical advantage they provide is f
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Sporting super spikes: how do they work?
In the lead-up to the athletics competitions at the Tokyo Olympic Games 2020, Shivani Dave takes look at how advances in running shoe technology are resulting in records being smashed. Talking to Geoff Burns, a postdoctoral research fellow at the University of Michigan who specialises in biomechanics, Shivani asks how so-called 'super spikes' work and if the mechanical advantage they provide is fa
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Making food from CO2 —>Circe's proprietary microbes have been genetically engineered to transform CO2 and hydrogen gas into valuable carbon-based compounds within their cells via fermentation, consuming the input CO2 rather than emitting it.
Circe's proprietary microbes have been genetically engineered to transform CO2 and hydrogen gas into valuable carbon-based compounds within their cells via fermentation, consuming the input CO2 rather than emitting it." title="" src="https://external-preview.redd.it/QC-PHFQrbaTA2BSKnI3bzFmjDW0TyL8eCRL0KH26Cdw.jpg?width=640&crop=smart&auto=webp&s=78b29137f8d3cb8ce93dda19377b11ffbbd5346e"> submitte
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NASA's Hubble Finds Evidence of Water Vapor on One of Jupiter's Moons
Water Vapor Using data from NASA's Hubble Space Telescope, scientists say they've found the first-ever evidence of water vapor in the atmosphere of Jupiter's moon Ganymede. It's an exciting discovery that supports the theory the moon's massive subsurface ocean could be capable of hosting alien life — and could also give us insights into the habitability of other Jupiter-like systems outside of ou
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Lab-made spider silk beats steel and Kevlar
Engineers have designed amyloid silk hybrid proteins and produced them in engineered bacteria. The resulting fibers are stronger and tougher than some natural spider silk, which is said to be one of the strongest, toughest materials on the Earth. To be precise, the artificial silk—dubbed "polymeric amyloid" fiber—was not technically produced by researchers, but by bacteria that were genetically e
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Supernova's 'fizzled' gamma-ray burst
On Aug. 26, 2020, NASA's Fermi Gamma-ray Space Telescope detected a pulse of high-energy radiation that had been racing toward Earth for nearly half the present age of the universe. Lasting only about a second, it turned out to be one for the record books — the shortest gamma-ray burst (GRB) caused by the death of a massive star ever seen.
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What Kind of Performance Should We Expect from Intel's Alder Lake?
Credit: John Burek Interest in Alder Lake is running high as we move into the back half of the year and closer to the CPU family's launch date. Alder Lake is intended to be a major step forward for both Intel and x86 CPU design in general. Historically, x86 CPUs have all been based on a cluster of identical CPU cores, in contrast to ARM, which has mixed big and little cores on the same SoC for a
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Tesla Autopilot Mistakes Moon for Yellow Traffic Light
Moonstruck Last week, a Tesla driver noticed that their car was giving off some odd readings as it cruised down the highway: it was confusing the Moon for an endless string of traffic lights. The glitch, which was caught on video by the vehicle's driver and spotted by Interesting Engineering , shows Tesla's Autopilot assisted-driving technology interpret the Moon as yellow traffic light after yel
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"Pull Me Up!" Dangerous Close Call for New Diver | Bering Sea Gold
Stream Bering Sea Gold on discovery+ ► https://www.discoveryplus.com/show/bering-sea-gold About Bering Sea Gold: In Nome, Alaska, the gold rush is on. Driven by gold fever and sometimes desperate need, miners pilot their ragtag dredges and dive with hoses to suck up gold from the bottom of the frigid, unpredictable Bering Sea. Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Follow Us on
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A functional analysis reveals extremely low redundancy in global mangrove invertebrate fauna [Ecology]
Deforestation results in habitat fragmentation, decreasing diversity, and functional degradation. For mangroves, no data are available on the impact of deforestation on the diversity and functionality of the specialized invertebrate fauna, critical for their functioning. We compiled a global dataset of mangrove invertebrate fauna comprising 364 species from 16 locations,…
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Tracking the transition to agriculture in Southern Europe through ancient DNA analysis of dental calculus [Anthropology]
Archaeological dental calculus, or mineralized plaque, is a key tool to track the evolution of oral microbiota across time in response to processes that impacted our culture and biology, such as the rise of farming during the Neolithic. However, the extent to which the human oral flora changed from prehistory…
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PIP4Ks impact on PI3K, FOXP3, and UHRF1 signaling and modulate human regulatory T cell proliferation and immunosuppressive activity [Immunology and Inflammation]
Regulatory T cells (Tregs) play fundamental roles in maintaining peripheral tolerance to prevent autoimmunity and limit legitimate immune responses, a feature hijacked in tumor microenvironments in which the recruitment of Tregs often extinguishes immune surveillance through suppression of T-effector cell signaling and tumor cell killing. The pharmacological tuning of Treg…
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A framework for localizing global climate solutions and their carbon reduction potential [Environmental Sciences]
Localized carbon reduction strategies are especially critical in states and regions that lack top-down climate leadership. This paper illustrates the use of coupled systems in assessments of subnational climate solutions with a case study of Georgia, a state located in the southeastern United States that does not have statewide climate…
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THAP1 modulates oligodendrocyte maturation by regulating ECM degradation in lysosomes [Neuroscience]
Mechanisms controlling myelination during central nervous system (CNS) maturation play a pivotal role in the development and refinement of CNS circuits. The transcription factor THAP1 is essential for timing the inception of myelination during CNS maturation through a cell-autonomous role in the oligodendrocyte lineage. Here, we demonstrate that THAP1 modulates…
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Estrogens influence female itch sensitivity via the spinal gastrin-releasing peptide receptor neurons [Neuroscience]
There are sex differences in somatosensory sensitivity. Circulating estrogens appear to have a pronociceptive effect that explains why females are reported to be more sensitive to pain than males. Although itch symptoms develop during pregnancy in many women, the underlying mechanism of female-specific pruritus is unknown. Here, we demonstrate that…
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Imperfect comb construction reveals the architectural abilities of honeybees [Ecology]
Honeybees are renowned for their perfectly hexagonal honeycomb, hailed as the pinnacle of biological architecture for its ability to maximize storage area while minimizing building material. However, in natural nests, workers must regularly transition between different cell sizes, merge inconsistent combs, and optimize construction in constrained geometries. These spatial obstacles…
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Nationwide evidence that education disrupts the intergenerational transmission of disadvantage [Psychological and Cognitive Sciences]
Despite overall improvements in health and living standards in the Western world, health and social disadvantages persist across generations. Using nationwide administrative databases linked for 2.1 million Danish citizens, we leveraged a three-generation approach to test whether multiple, different health and social disadvantages—poor physical health, poor mental health, social welfare…
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Three-dimensional label-free visualization and quantification of polyhydroxyalkanoates in individual bacterial cell in its native state [Applied Biological Sciences]
Polyhydroxyalkanoates (PHAs) are biodegradable polyesters that are intracellularly accumulated as distinct insoluble granules by various microorganisms. PHAs have attracted much attention as sustainable substitutes for petroleum-based plastics. However, the formation of PHA granules and their characteristics, such as localization, volume, weight, and density of granules, in an individual live bact
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Rare crested rat subfossils unveil Afro-Eurasian ecological corridors synchronous with early human dispersals [Earth, Atmospheric, and Planetary Sciences]
Biotic interactions between Africa and Eurasia across the Levant have invoked particular attention among scientists aiming to unravel early human dispersals. However, it remains unclear whether behavioral capacities enabled early modern humans to surpass the Saharo–Arabian deserts or if climatic changes triggered punctuated dispersals out of Africa. Here, we report…
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Social change and cohort differences in group-based arrest trajectories over the last quarter-century [Social Sciences]
This article draws on official criminal histories for multiple birth cohorts spanning a 17-y difference in birth year to study how social change can alter our understanding of influential theories and policies about criminal offender groups. Arrest histories are linked to comprehensive longitudinal measurement on over 1,000 individuals originally from…
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Multicomponent nature underlies the extraordinary mechanical properties of spider dragline silk [Applied Biological Sciences]
Dragline silk of golden orb-weaver spiders (Nephilinae) is noted for its unsurpassed toughness, combining extraordinary extensibility and tensile strength, suggesting industrial application as a sustainable biopolymer material. To pinpoint the molecular composition of dragline silk and the roles of its constituents in achieving its mechanical properties, we report a multiomics…
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Cyclic nucleotide phosphodiesterase 1C contributes to abdominal aortic aneurysm [Pharmacology]
Abdominal aortic aneurysm (AAA) is characterized by aorta dilation due to wall degeneration, which mostly occurs in elderly males. Vascular aging is implicated in degenerative vascular pathologies, including AAA. Cyclic nucleotide phosphodiesterases, by hydrolyzing cyclic nucleotides, play critical roles in regulating vascular structure remodeling and function. Cyclic nucleotide phosphodiesterase
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Recovery of assessed global fish stocks remains uncertain [Sustainability Science]
Concerns over overexploitation have fueled an ongoing debate on the current state and future prospects of global capture fisheries, associated threats to marine biodiversity, and declining yields available for human consumption. Management reforms have aimed to reduce fishing pressure and recover depleted stocks to biomass and exploitation rates that allow…
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Correction for Madan et al., Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody [Corrections]
APPLIED BIOLOGICAL SCIENCES Correction for "Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody," by Bharat Madan, Baoshan Zhang, Kai Xu, Cara W. Chao, Sijy O'Dell, Jacy R. Wolfe, Gwo-Yu Chuang, Ahmed S. Fahad, Hui Geng, Rui Kong, Mark K. Louder, Thuy Duong…
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Correction for Fournier et al., Predicting future invaders and future invasions [Corrections]
ECOLOGY Correction for "Predicting future invaders and future invasions," by Alice Fournier, Caterina Penone, Maria Grazia Pennino, and Franck Courchamp, which was first published March 29, 2019; 10.1073/pnas.1803456116 (Proc. Natl. Acad. Sci. U.S.A. 116, 7905–7910). The authors note that due to a technical error in the script that selected the…
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Correction for Sun et al., Selective filtering defect at the axon initial segment in Alzheimer's disease mouse models [Corrections]
NEUROSCIENCE Correction for "Selective filtering defect at the axon initial segment in Alzheimer's disease mouse models," by Xiaqin Sun, Yu Wu, Mingxue Gu, Zhuo Liu, Yuanlin Ma, Jun Li, and Yan Zhang, which was first published September 17, 2014; 10.1073/pnas.1411837111 (Proc. Natl. Acad. Sci. U.S.A. 111, 14271–14276). The authors note…
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Correction for Lucy Edwards et al., Direction of flagellum beat propagation is controlled by proximal/distal outer dynein arm asymmetry [Corrections]
CELL BIOLOGY Correction for "Direction of flagellum beat propagation is controlled by proximal/distal outer dynein arm asymmetry," by Beatrice Freya Lucy Edwards, Richard John Wheeler, Amy Rachel Barker, Flávia Fernandes Moreira-Leite, Keith Gull, and Jack Daniel Sunter, which was first published July 20, 2018; 10.1073/pnas.1805827115 (Proc. Natl. Acad. Sci. U.S.A….
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Correction for Saiz-Lopez et al., Photochemistry of oxidized Hg(I) and Hg(II) species suggests missing mercury oxidation in the troposphere [Corrections]
CHEMISTRY Correction for "Photochemistry of oxidized Hg(I) and Hg(II) species suggests missing mercury oxidation in the troposphere," by Alfonso Saiz-Lopez, Oleg Travnikov, Jeroen E. Sonke, Colin P. Thackray, Daniel J. Jacob, Javier Carmona-García, Antonio Francés-Monerris, Daniel Roca-Sanjuán, A. Ulises Acuña, Juan Z. Dávalos, Carlos A. Cuevas, Martin Jiskra, Feiyue Wang,…
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Correction for Wang et al., Embryonic stem cell-derived hematopoietic stem cells [Corrections]
MEDICAL SCIENCES Correction for "Embryonic stem cell-derived hematopoietic stem cells," by Yuan Wang, Frank Yates, Olaia Naveiras, Patricia Ernst, and George Q. Daley, which was first published December 15, 2005; 10.1073/pnas.0506127102 (Proc. Natl. Acad. Sci. U.S.A. 102, 19081–19086). The authors wish to note the following: "Regarding Fig. S10 in the…
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This Game Changing Supplement Fights Unwanted Adderall Side Effects
According to a survey conducted by the American Journal of Psychiatry, at least 16-million Americans over the age of 18 use stimulants like Adderall, Ritalin, or Modafinil. Regardless of which stimulants you use, the side effects are commonly the same and they're not very fun. This can include poor impulse control, anxiety, headaches, brain fog, moodiness, bloating, irritability, diminished cogni
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New Tech Turns Plastic Waste Into Food
Dig In Heaps and heaps of plastic garbage are choking the planet . But thankfully, a scientist duo has an interesting new plan to tackle it: turning plastic garbage into fine cuisine, instead of throwing it into a dump or the ocean. University of Illinois Urbana-Champaign bioengineer Ting Lu and Michigan Technological University biologist Stephen Techtmann won an award called the 2021 Future Insi
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Silicone wristbands detect chemicals harmful to pregnancy
Inexpensive, convenient silicone wristbands can measure exposure to a class of chemicals that can be harmful during pregnancy, researchers report. The researchers found that the wristbands, when used as passive samplers, have the ability to bind smaller molecular weight semi-volatile polycyclic aromatic hydrocarbons (PAHs) in a similar pattern as active sampling. PAHs are a class of chemicals tha
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6 things to know about the slow COVID-19 vaccine rollout
As the United States flounders to meet its COVID-19 vaccine targets—only 49% of Americans are fully vaccinated to date. The especially contagious Delta variant has the daily number of new cases back on the upswing, with a 171% increase in new cases compared to two weeks ago. Around the world, the situation is even more dire. Despite the fact that experts predict nearly 11 billion doses of vaccine
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Study: Countries' wealth inequality independent from income inequality, linked to distribution of housing equity
Most of what we know from prior research about which countries are more unequal than others is based on measures of income inequality. In their new study, "The Wealth Inequality of Nations," appearing in the August 2021 issue of the American Sociological Review, authors Fabian T. Pfeffer and Nora Waitkus show that comparing countries in terms of their wealth inequality instead of income inequality
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Wild pigs release more CO2 than 1 million cars
By uprooting carbon trapped in soil, wild pigs are releasing around 4.9 million metric tonnes (about 5.4 million tons) of carbon dioxide every year worldwide. That's the equivalent of 1.1 million cars. Researchers used predictive population models, coupled with advanced mapping techniques, to pinpoint the climate damage wild pigs cause across five continents. The globe's ever-expanding population
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Slow recovery after DST 'spring forward' depends on your DNA
Every spring, the daylight saving time shift robs people of an hour of sleep—and a new study shows that DNA plays a role in how much the "spring forward" time change affects people. People whose genetic profile makes them more likely to be "early birds" the rest of the year can adjust to the time change in a few days, the study shows. But those who tend to be "night owls" could take more than a w
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Americans owe at least $140 billion in medical debt
Americans are actually saddled with at least $140 billion in outstanding medical debt, research finds. The study from economist Neale Mahoney indicates a grimmer picture than the earlier $81 billion figure—heavily cited during the last presidential election cycle—which was based on a narrower measure of medical debt and a restricted sample of people. As reported in the Journal of the American Med
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Hack your brain for better problem solving
This article was originally published on Big Think Edge. Problem-solving skills are in demand. Every job posting lists them under must-have qualifications, and every job candidate claims to possess them, par excellence . Young entrepreneurs make solutions to social and global problems the heart of their mission statements , while parents and teachers push for curricula that encourage critical-thi
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Quit Nicotine Before You Quit Smoking With Hemp Flower Cigarettes
It seems safe to say that these days, pretty much everyone, smoker and non-smoker alike, is aware that nicotine is bad for you. It's addictive for one thing, and it also has plenty of other negative side-effects on your physical and mental health. But one thing you might not know if you're a smoker is that you don't really have to give up smoking in order to stop using nicotine. Instead, you can
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Function of sex chromosomes in turtles
A new study sheds light on how organisms have evolved to address imbalances in sex chromosomes. The study looks at a species of softshell turtle, but the results could help to illuminate an important evolutionary process in many species. The research centers on a process known as sex chromosome dosage compensation.
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New methane concentration technologies for monitoring greenhouse gas emissions
Methane concentrations in the atmosphere have more than doubled over the last 150 years and mitigation of methane emissions will play a vital role in enabling climate change mitigation strategies. Understanding current and future methane inventories at a regional scale will be a key element in developing and implementing successful solutions. Current regional scale isotopic methane data is not ava
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The advantage of 2D metal-organic framework nanosheets in sensing applications
In recent years, fluorescent metal-organic frameworks (MOFs) have been demonstrated as a promising strategy for constructing sensors. However, most of the research studies on fluorescent MOF sensors have focused on the design and synthesis of three-dimensional (3D) MOF crystals on the order of micrometers and have not exerted the best detection performance of MOF structures. Two-dimensional (2D) M
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Acoustic tweezers can pick up objects without physical contact
Researchers from Tokyo Metropolitan University have developed a new technology which allows non-contact manipulation of small objects using sound waves. They used a hemispherical array of ultrasound transducers to generate a 3D acoustic field that stably trapped and lifted a small polystyrene ball from a reflective surface. Their technique employs a method similar to laser trapping in biology, but
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Preliminary Research Explains Why the Delta Variant Is So Dangerous
A team of Chinese scientists says that it's uncovered the delta variant's secret weapon. Right when things started to look like the COVID-19 pandemic was in its final act — at least in countries with access to vaccines — the delta variant reared its ugly head and started a new surge. Experts have known for a while that the delta variant is more infectious than the original strain of SARS-CoV-2 th
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Did you solve it? Clueless sudoku
The solutions to today's puzzles Earlier today I set you three 'clueless' Sudoku and an 'almost clueless' Killer Sudoku. For discussion and tips you can read the original column here . For a printable page of all the puzzles click here. Scroll down for the solutions. Continue reading…
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Single drop of dried blood can reveal athlete doping
A new method uses blood droplets to easily and effectively detect athletes who have taken performance-enhancing drugs. The method received approval from the World Anti-Doping Agency and could be tested at the Tokyo Olympics. We probably only know the tip of the iceberg when it comes to the number of doped athletes. Indeed, studies show that considerably more athletes use performance-enhancing dru
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Rare inherited variants in previously unsuspected genes may confer significant risk for autism
Researchers have identified a rare class of genetic differences transmitted from parents without autism to their affected children with autism and determined that they are most prominent in "multiplex" families with more than one family member on the spectrum. These findings are reported in Recent ultra-rare inherited variants implicate new autism candidate risk genes, a new study published in Nat
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