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SAMME ANTIFROST-PROTEIN PÅVIST HOS UBESLÆGTEDE FISKEARTER: To survive in cold temperatures, living organisms have developed anti freezing protein, but as a surprise for scientists, two unrelated groups of fish have the same gene. Scientists have confirmed that it is not through crossbreeding.
ERSTATNING FOR LYSMIKROSKOPET: The new microscope uses quantum entanglement to replace light used to examine biological systems. The light used is so strong that it destroys the cells in a few seconds, the new microscope has overcome this barrier. The quantum entanglement now could be integrated in other technologies as well.
National Geographic has recognized the Southern Ocean as the fifth official ocean. The cartographic update doesn't surprise researchers who study the importance of the waters surrounding Antarctica. (Image credit: Alexander Gerst/ESA via Getty Images)
An advanced artificial intelligence technique known as deep learning can predict major adverse cardiac events more accurately than current standard imaging protocols, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2021 Annual Meeting. Utilizing data from a registry of more than 20,000 patients, researchers developed a novel deep learning network that has t
Simone Biles is the greatest athlete in the world today. For me, this isn't a debate. It's a statement of fact. On Sunday, she won a record seventh United States gymnastics championship , continuing her jaw-dropping winning streak in every all-around competition she's entered since 2013. The 24-year-old hasn't lost in eight years. Typical gymnasts her age aren't beating all their rivals by the bi
Extreme Danger Despite the Pentagon's best efforts, we still have no idea what explains a series of Navy pilot encounters with UFOs that seemingly crossed the sky at hypersonic speeds and defied the laws of physics. And if the latest rumors are to be believed , an upcoming report by the government isn't going to give us any more answers than we already have. The theory that extraterrestrials coul
While Senator Joe Manchin is demanding that both parties agree on any further federal voting-rights legislation, a new study quantifies how completely Republicans have excluded Democrats from the passage of the restrictive voting laws proliferating in red states. In places such as Florida, Georgia, Arizona, Iowa, Kansas, and Montana, the most restrictive laws approved this year have passed on tot
Cells contain machinery that duplicates DNA into a new set that goes into a newly formed cell. That same class of machines, called polymerases, also build RNA messages, which are like notes copied from the central DNA repository of recipes, so they can be read more efficiently into proteins. But polymerases were thought to only work in one direction DNA into DNA or RNA. This prevents RNA messages
The specific traits of a plant's roots determine the climatic conditions under which a particular plant prevails. A new study led by the University of Wyoming sheds light on this relationship—and challenges the nature of ecological trade-offs.
A team of researchers from the University of Sydney, the ARC-Plant Protection Research Institute and York University, has found that workers in a species of honeybee found in South Africa reproduce by making near-perfect clones of themselves. In their paper published in Proceedings of the Royal Society B, the group describes their study of the bees and what they learned about them.
3D tumors that disintegrate within a few days thanks to the action of a well-known omega-3 (DHA, found mainly in fish) — this is a promising discovery. Hungry for fatty acids, tumor cells in acidosis gorge themselves on DHA but are unable to store it correctly and literally poison themselves. The result? They die.
An article suggests the natural light show starts when disturbances on the sun pull on Earth's magnetic field, creating cosmic waves that launch electrons into the atmosphere to form the aurora. (Image credit: Jonathan Nackstrand/AFP via Getty Images)
Huge star, 25,000 light years away, dims by 97% then slowly returns to former brightness Astronomers have spotted a giant blinking star, 100 times the size of the sun, lurking near the heart of the Milky Way. Telescope observations revealed that over a few hundred days the enormous star, which lies more than 25,000 light years away, dimmed by 97% and then slowly returned to its former brightness.
Archeologists in Israel made an incredibly rare discovery in the ancient industrial zone of Yavneh, a central Israeli city: a 1,000 year old chicken egg. Astonishingly, the egg lay underground, preserved for all those years — until, tragically, they accidentally broke it in a lab run by archeologists from the Israel Antiquities Authority, as Haaretz reports . It's a scientific loss, but also a po
We Get Signal A years-long study using the CHIME telescope in Canada has uncovered over 500 new fast-radio bursts (FRBs), mysterious and fleeting signals emitted from the far reaches of space. The scientists found that there are some key differences between different FRBs, some of which were one-off bursts and some of which rapidly repeated, according to CNN . That lead them to believe that the d
Montana now has six mobile crisis response teams — up from one in 2019 — with more in the works. Each team has a different makeup, but all use mental health support to diffuse tricky situations. (Image credit: Katheryn Houghton/KHN)
Variant first discovered in India is thought to spread more easily and be more resistant to vaccines Coronavirus – latest updates See all our coronavirus coverage More than 90% of Covid cases in the UK are now down to the coronavirus Delta variant first discovered in India, data has revealed, as the total number of confirmed cases passed 42,000. Also known as B.1.617.2, the Delta variant has been
The major blood vessel of the penis splits into two main branches which each supply two of the four penile heads The penis of an echidna has four heads but only two become erect at any one time. Now, Australian researchers have uncovered why. Scientists discovered the mammal has unusual reproductive anatomy that causes male echidnas to ejaculate from only two of their four penile heads at one tim
One of the last times I saw my interpreter Ali, we were driving through a valley in southeastern Afghanistan when a vehicle in our convoy struck an IED. An ambush followed. Muzzle flashes lit up the rocky hillside as we pried the bodies of four Afghan soldiers out of their mangled vehicle, including Mortaza, a friend of Ali's. I remember the two of us putting pieces of him in a vinyl body bag. Af
Volcano Powered El Salvador recently became the first sovereign nation in the world to make Bitcoin legal tender. Now, the small country's president Nayib Bukele has an even wilder plan to realize his crypto dreams: volcano-powered cryptocurrency mining. It's yet another wild turn for a country that has chosen to go all in on the wildly volatile digital currency — recent tumbles in price be damne
Over the past century, quantum field theory has proved to be the single most sweeping and successful physical theory ever invented. It is an umbrella term that encompasses many specific quantum field theories — the way "shape" covers specific examples like the square and the circle. The most prominent of these theories is known as the Standard Model, and it is this framework of physics that has..
Skygazers – with appropriate eye protection – could see much of sun being obscured on Thursday morning Solar eclipse 2021: the crescent sun – in pictures A celestial phenomenon is underway, with observers in the UK able to see a crescent sun while viewers in the Arctic enjoy an annular solar eclipse. An annular eclipse occurs when the sun and moon are exactly in line with the Earth, but the appar
"He loved authority and business. He had a high sense of his own personal dignity," one commentator observed . "He was not altogether destitute of a sentiment which bore some affinity to patriotism … His second wish was to be feared and respected abroad. But his first wish was to be absolute master at home." He came to power, succeeding a popular head of state who had tried to restore normalcy, a
Innova tests' performance not proven and they should be returned to manufacturer or thrown in bin, says FDA Coronavirus – latest updates See all our coronavirus coverage The US Food and Drug Agency (FDA) has raised significant concerns about the rapid Covid test on which the UK government has based its multibillion-pound mass testing programme . In a scathing review , the US health agency suggest
This month the Pentagon will release its much-awaited UFO report. Extraterrestrial buffs think they'll be vindicated – but they've gotten a bit ahead of themselves There is a tidal wave of interest building up around an imminent Pentagon report on the subject of UFOs, or, as they are often referred to now, UAPs (Unidentified Aerial Phenomena). A sense of heady enthusiasm has swept over the UFO co
HOW FAR WE HAVE COME! (not that far actually) Sign up here to get an email whenever First Dog cartoons are published Get all your needs met at the First Dog shop if what you need is First Dog merchandise and prints Continue reading…
Cambridge research suggests foot problem was more common after Blackadder-style shoe became popular From waist-squeezing corsets to crinoline skirts, fashion has rarely been about comfort – or safety. Now researchers have revealed that even in medieval times, men and women could become martyrs to fashion, linking a trend in pointy shoes to a rise in the prevalence of bunions. Bunions – or hallux
Adi Utarini had her first of two bouts of dengue fever in 1986, when she was still a medical student. Within a few hours, she spiked a temperature of 104 degrees Fahrenheit and couldn't stand up, because her knee was shaking so badly. Within a few days, she was in the hospital. That experience is common in Utarini's home city of Yogyakarta, Indonesia: It has one of the highest rates of dengue in
I f you ask Roger Dow, what's happening at the border is "monstrous"—a prolonged disaster that gets worse by the day. "It is a crisis," he told me by phone last week. Dow is the CEO of the U.S. Travel Association, and he wasn't talking about the thousands of migrants surging illegally across the southern border with Mexico or the unaccompanied children detained in overcrowded shelters. Dow was ta
In a series of definitive pieces that earned him the 2021 Pulitzer Prize for explanatory reporting, The Atlantic 's Ed Yong anticipated the course of the coronavirus pandemic, clarified its dangers, and illuminated the American government's disastrous failure to curb it. Yong, who has been a staff writer at The Atlantic since 2015, began warning readers about the fragility of America's pandemic p
Monday's announcement will come as coronavirus case are rising at fastest rate since second wave Coronavirus – latest updates See all our coronavirus coverage The lifting of all lockdown restrictions in England is likely to be delayed for up to a month from the planned date of 21 June, government sources have told the Guardian. It comes as coronavirus cases in England are rising at their fastest
When the human genome was first deemed "complete" in 2000, the news was met with great international fanfare. The two rival groups vying to finish the genome first—one a large government-led consortium, the other an underdog private company—agreed to declare joint success. They shook hands at the White House. Bill Clinton presided. Tony Blair beamed in from London . "We are standing at an extraor
Bitcoin mining has taken a lot of heat for being harmful to the environment since it requires massive amounts of electricity to generate the invisible currency. (Image credit: Stanley Estrada/AFP via Getty Images)
The blood-sucking critters are capable of thriving along the West Coast, according to new research, though experts don't exactly know how they're picking up the bacterium that causes the illness. (Image credit: James Gathany/CDC via AP)
Lasso the Moon Congressman Louie Gohmert suggested an unusual approach to tackling climate change during a recent hearing: somehow altering the orbit of the Moon in order to change the weather down here on Earth. Gohmert, a steadfast opponent of climate change measures, was questioning Forest Service associate deputy chief Jennifer Eberlien during a House Natural Resources Committee hearing, acco
Solid Foundation In order to develop artificial general intelligence (AGI), the sort of all-encompassing AI that we see in science fiction, we might need to merely sit back and let a simple algorithm develop on its own. Reinforcement learning, a kind of gamified AI architecture in which an algorithm "learns" to complete a task by seeking out preprogrammed rewards, could theoretically grow and lea
Space Visitors China is set to launch the first astronauts to its new Earth-orbiting space station. A Long March 2F rocket rolled out onto the launch pad on Wednesday, as SpaceNews reports, to send three astronauts to the Tianhe core module of China's space station, which launched into orbit in April of this year. There's a lot we don't know yet, including the exact launch date and the identities
On these maps, each hexagon represents one-thousandth of the world's economy. That makes it easy to compare the GDP of regions and nations across the globe. There are versions for nominal GDP and GDP adjusted for purchasing power. Shanghai's skyline at night. According to the GDP (PPP) map, China is the world's largest economy. But that oft-cited statistic says more about the problems of PPP as a
From New Jersey to Milton Keynes, skygazers in the northern hemisphere were able to see a partial solar eclipse, witnessing a crescent sun in an eclipsed sunrise in some parts of the world Solar eclipse 2021: spectacle visible across UK and Ireland Continue reading…
E very December, when Christmas rolls around, I hear Mariah Carey's "All I Want for Christmas Is You" and I think of the Pulse nightclub shooting in Orlando, five years ago in the middle of June—literally as far from Christmas as you can get. I had volunteered to fly to Florida to cover the massacre for NPR. Each time my producer and I climbed into our rental car, she plugged in her phone and the
Organisation urges governments to be cautious as societies open up and Delta variant advances Coronavirus – latest updates See all our coronavirus coverage Covid-19 infections, hospitalisations and deaths are falling fast across Europe, but the risk of a deadly autumn resurgence remains high as societies open up and the more transmissible Delta variant advances, the World Health Organization (WHO
" How to Build a Life " is a weekly column by Arthur Brooks, tackling questions of meaning and happiness. F or many people, the cruelest part of daily life is the transition between wakefulness and sleep. When you should be sleeping, you want to be awake; when you should be awake, you want to stay asleep. It is easy to regard sleep as a torment: hard to attain and then hard to give up, day after
India's Hindu-nationalist prime minister, Narendra Modi ( upper right ), and three of Bollywood's biggest Muslim stars ( left to right ): Salman Khan, Shah Rukh Khan, and Aamir Khan ( Illustration by Geoff Kim; Raveendran / AFP; Visual China Group / Getty; Chirag Wakaskar / Getty; Manoj Verma / Hindustan Times / Getty ) This article was published online on June 10, 2021 and updated at 10:15 a.m.
After two of the driest years in decades, many of California's reservoirs are expected to reach record-setting lows this summer, four years after exiting the state's most recent drought emergency. Lake Oroville, the second-largest reservoir in California, stands at about 37 percent of its capacity. Governor Gavin Newsom has declared a drought emergency for most of the state, while farmers are wor
Researchers from Penn's Department of Physics and Astronomy have developed a new method for better understanding the relationship between a star's chemical composition and planet formation. The study was led by recent graduate Jacob Nibauer for his senior thesis with Bhuvnesh Jain and was co-supervised by former Penn postdoc Eric Baxter. The researchers found that the majority of stars in their da
Sometimes, the actions a government takes look bad at the time, but posterity treats them kindly . Other times, a president might look good in the moment but see his reputation sink in retrospect . Then there's the Trump administration, and especially its Justice Department, which looked bad when it was in power and now looks even worse. Late yesterday, The New York Times reported that the Justic
News that the Amazon overlord is about to jet off has got the Virgin boss clamouring to get there first. You can do it, Richard! It's famously impossible to take a bathroom break during a rocket launch, meaning Jeff Bezos will soon experience what it's like to be one of his warehouse workers . Or, as the Amazon boss put it last week: "To see the Earth from space … changes your relationship with h
Earlier this week, the Food and Drug Administration overruled—to much criticism—its own scientific advisory committee and approved the Alzheimer's treatment Aduhelm. The agency made this decision despite thin evidence of the drug's clinical efficacy and despite its serious side effects, including brain swelling and bleeding. As a result, a serious risk now exists that millions of people will be p
Those with a certain genetic makeup more likely to develop motor neurone disease, study confirms Regular strenuous exercise raises the risk of developing motor neurone disease (MND) in people who are genetically predisposed to the condition, researchers say. Scientists at the University of Sheffield found a causal relationship between high intensity physical activity and the disorder among those
You can see the faint stubble coming in on his upper lip, the wrinkles on his forehead, the blemishes on his skin. He isn't a real person, but he's meant to mimic one—as are the hundreds of thousands of others made by Datagen, a company that sells fake, simulated humans. These humans are not gaming avatars or animated characters for movies. They are synthetic data designed to feed the growing app
Way back in January, I was idly thumbing through Instagram when I received a message that shook me like a nascent martini. "Did you hear that Taking Cara Babies donated to Trump ?" a friend wrote. This sentence likely makes no sense to you, unless you've had a baby sometime in the past few years. Taking Cara Babies is the brand name for Cara Dumaplin, a neonatal nurse turned baby-sleep expert who
China released a series of new photos from its Zhurong Mars rover this morning. The images, debuted on state media , are indeed breathtaking — but they came alongside braggadocious verbiage that emphasized the mission's "complete success," as well as the significance of the Chinese flag flying on the Red Planet. "The images were unveiled at a ceremony in Beijing, signifying the complete success o
Everyone give a warm "welcome back!" to the Royal Caribbean cruise line, which is back in operation after a year of pandemic shutdown and already up to some of its old tricks. Stop us if you've heard this one before , but that trick is taking a tropical vacation and turning it into a potential superspreader event: WIC News reports that two guests on the company's first cruise have already tested
Illustration by Kensuke Koike; Bettmann / Getty This article was published online on June 11, 2021. I n the early and macabre days of coronavirus shutdowns, Edgar Allan Poe was trending . " The Masque of the Red Death ," his Gothic tale from 1842, became in March of 2020 a go-to source for allegory: A prince whose state is overrun with something like hemorrhagic fever invites 1,000 noble friends
Operators of Rosalind Franklin rover practise controlling it in preparation for Martian landing in June 2023 A precise replica of the European Space Agency's ExoMars Rosalind Franklin rover has begun a series of test drives at the Aerospace Logistics Technology Engineering Company's Mars terrain simulator in Turin, Italy. Rover operators will practise controlling the rover in preparation for its
An optical illusion at the Eiffel Tower, scenes from the French Open, a surfing competition in El Salvador, a presidential election in Peru, Olympic qualifying skateboarding trials in Italy, a giant sinkhole in Mexico, a sunrise annular eclipse seen in New York City, a platypus health check in Australia, and much more
Many animals have evolved camouflage tactics for self-defense, but some butterflies and moths have taken it even further: They've developed transparent wings, making them almost invisible to predators.
Extraordinary claims, such as that UFOs have visited our planet or that aliens exist, require extraordinary evidence. Personal testimonies are simply insufficient to conclude that UFOs and aliens are real. Good luck having a rational conversation about it with anyone on Twitter. If you were hoping, based on the title, that I was going to describe the time I saw strange lights moving at inexplicab
Hiromitsu Takeuchi, a lecturer at the Graduate School of Science, Osaka City University, and a researcher at the Nambu Yoichiro Institute of Theoretical and Experimental Physics (NITEP), has theoretically identified the nature of a mysterious topological defect produced by the recently discovered non-equilibrium time evolution of spontaneous symmetry breaking (SSB). Since the SSB realized in this
Acoustic waves in gases, liquids, and solids usually travel at an almost constant speed of sound. So-called rotons are an exception: their speed of sound changes significantly with the wavelength, and it is also possible that the waves travel backward. Researchers at Karlsruhe Institute of Technology (KIT) are studying the possibilities of using rotons in artificial materials. These computer-desig
Brown dwarfs are the cosmic equivalent of tweeners. They're too massive to be planets and too small to sustain nuclear fusion in their cores, which powers stars. Many brown dwarfs are nomadic. They do not orbit stars but drift among them as loners.
Ethan and Aiden Dvash-Banks are twin brothers—born just four minutes apart on the same September day in the same hospital room in Ontario, Canada. But shortly after their birth in 2016, the U.S. State Department decided that the two boys were very different in the eyes of American law: Aiden was a U.S. citizen but Ethan, the brother with whom he'd shared a womb, was not. The reasoning, as it were
The last 15 years have been tough times for many Americans, but there are now encouraging signs of a turnaround. Productivity growth, a key driver for higher living standards, averaged only 1.3% since 2006, less than half the rate of the previous decade. But on June 3, the US Bureau of Labor Statistics reported that US labor productivity increased by 5.4% in the first quarter of 2021. What's bett
New Crater Dedicated Mars watchers will recall that this morning, China released new photos from the Red Planet that showed off its lander, rover, and the beautiful landscape of the Utopia Planitia. Space journalist Jonathan O'Callaghan pointed out something interesting about one of the photos : you can see a deep hole that the lander punched in the Martian ground — a fun observation, but also a
Officially Sidelined The Bitcoin Mining Council, a voluntary group of crypto miners and enthusiasts, formally announced its debut on Friday. But it seems to be leaving an important figure behind: Elon Musk. "Elon Musk has no role at the BMC," reads part of the group's launch statement . "The extent of his involvement was joining an educational call with a group of North American companies to disc
Brown Energy Bitcoin mining operations are shockingly energy-intensive due to stacks of processors working away in an attempt to extract some crypto. That's led to growing concerns about cryptocurrencies being bad for a planet already being hit by the impacts of climate change — Bitcoin alone already consumes more energy than several countries — so one farmer is taking an unusual approach to clea
Researchers using the Atacama Large Millimeter/submillimeter Array (ALMA) discovered a titanic galactic wind driven by a supermassive black hole 13.1 billion years ago. This is the earliest example yet observed of such a wind to date and is a telltale sign that huge black holes have a profound effect on the growth of galaxies from the very early history of the universe.
Last month, self-driving technology company TuSimple shipped a truckload of watermelons across the state of Texas ten hours faster than normal. They did this by using their automated driving system for over 900 miles of the journey. The test drive was considered a success, and marked the beginning of a partnership between TuSimple and produce distributor Guimarra. This is one of the first such pa
Cicadas Rising On Tuesday, a White House press plane was grounded by a swarm of Brood X cicadas that had recently emerged from their 17 year slumber. The tiny critters managed to get into the engine, preventing the plane from leaving ahead of Biden on his first trip overseas as president, The Wrap reports . In fact, the attack got so bad, one particularly adventurous cicada appears to have manage
A pool of neural stem cells that ordinarily lies dormant in the brains of adult mice spawns two types of never-before-documented glial cells when artificially reactivated, potentially pointing to a novel mechanism of brain plasticity.
Bitcoin Bust Authorities in China just arrested over 1,100 people accused of laundering cryptocurrency, according to an announcement from the Ministry of Public Security. The various arrests, which targeted 170 gangs throughout the country, was the latest chapter in a broader crackdown on fraud and other financial crimes, Gizmodo reports . Chinese President XI Jinping called for a greater focus o
This pandemic's precise origins may never be certain. We must address both zoonotic transmission risks and lab security When something goes terribly wrong, it is human instinct to look for the human hand – perhaps to reassure ourselves that life is not wholly beyond our control. As the flu pandemic reached the US just over a century ago, some blamed German agents . So it wasn't surprising when pe
Pharmaceutical researcher with a flair for business who brought a string of vital drugs to market In 1960 the chemist Ronald Cresswell, who has died aged 86, had a lucky break. As a result of travelling from Glasgow to take up a post in New York he attended a conference of the American Chemical Society, met the biochemist George Hitchings, and they bonded over their mutual interest in folic acid.
A combined team of researchers from the Weizmann Institute of Science in Israel and the California Institute of Technology in the U.S. has calculated the weight of all the SARS-CoV-2 viruses infecting people around the world at any given time. In their paper published in Proceedings of the National Academy of Sciences, the group describes how they made their calculations and explain how their work
This article contains spoilers for In the Heights. In The Heights , the director Jon M. Chu's Hollywood adaptation of the groundbreaking Broadway musical, is ostensibly a tale about the aspirational young. Its focus stays mostly on some dreamers (and a "Dreamer") living in the Upper Manhattan neighborhood of Washington Heights. They form an ensemble cast of working-class Latino characters—immigra
Astronomers from the Andrés Bello National University, Chile, and elsewhere, have discovered a new nearby globular cluster (GC) with extreme kinematics. The newly found cluster, designated VVV-CL160, has an unusually large proper motion when compared to other galactic GCs. The finding is reported in a paper published on arXiv.org.
After months of getting very little coverage, the lab-leak theory for the origins of COVID-19—which holds that the virus emerged from a research setting—is now a source of endless chatter. Vanity Fair has a new, 12,000-word investigative feature on the subject, while lab-leak op-eds continue their exponential spread across the pages of The Washington Post , The Wall Street Journal , and The New Y
"That's not my face," Tori Dawn thought after opening TikTok to make a video in late May. The jaw reflected back on the screen was wrong: slimmer and more feminine. And when they waved their hand in front of the camera, blocking most of their face from the lens, their jaw appeared to pop back to normal. Was their skin also a little softer? On further investigation, it seemed as if the image was b
When nature vanishes, people of color and low-income Americans disproportionally lose critical environmental and health benefits—including air quality, crop productivity and natural disease control—a new study in Nature Communications finds.
The European Space Agency (ESA) has announced that it's also planning to take a trip to Venus. It'll be joining NASA, which recently announced two missions to our closest planetary neighbor, a planet that NASA hasn't visited in over 30 years. The rush of interest in Venus shows that scientists are itching to study the second planet from the Sun, which shares plenty of qualities with our own — des
There are a lot of stars in the universe — and while there are many different types, pretty much all of them shine consistently. That's why scientists were so puzzled to discover an "exceptionally rare" star, located toward the center of our own galaxy, that appears to be blinking on and off. The star in question, which is 100 times the size of our own Sun and which has been dubbed VVV-WIT-08 — t
An estimated 8 million tons of plastic trash enters the ocean each year, and most of it is battered by sun and waves into microplastics—tiny flecks that can ride currents hundreds or thousands of miles from their point of entry.
Paleoclimatologist Niels de Winter and colleagues developed an innovative way to use the clumped isotope method to reconstruct climate in the geological past on the seasonal scale. They show that dinosaurs had to deal with hotter summers than previously thought. The results suggest that in the mid latitudes, seasonal temperatures will likely rise along with climate warming, while seasonal differen
Covid cases are on the rise in England, and a fast-spreading variant may be to blame. B.1.617.2, which now goes by the name Delta, first emerged in India, but has since spread to 62 countries, according to the World Health Organization. Delta is still rare in the US. At a press conference on Tuesday, the White House's chief medical advisor, Anthony Fauci, said that it accounts for just 6% of case
The human heart contracts about 70 times per minute, while that of a rat contracts over 300 times; what accounts for this difference? In a new study publishing 10th June in the open-access journal PLOS Biology, led by Michael Geeves and Mark Wass of the University of Kent and Leslie Leinwand from the University of Colorado Boulder, reveal the molecular differences in the heart muscle protein beta
The Atlantic staff writer Ed Yong has won the 2021 Pulitzer Prize for Explanatory Reporting. He was awarded journalism's top honor for his defining coverage of the coronavirus pandemic and how America failed in its response to the virus. This is The Atlantic 's first Pulitzer Prize. Yong anticipated the course of the pandemic, clarified its dangers, and illuminated the American government's disas
Each installment of " The Friendship Files " features a conversation between The Atlantic 's Julie Beck and two or more friends, exploring the history and significance of their relationship. This week she talks with two amateur surfers who formed a close friendship despite their age gap. They discuss "surf etiquette," how the solitary sport created a rich community for them in Hawaii, and the val
Vaccines are absolutely crucial to keeping the entire planet healthy. None of us is safe until all of us are safe. But low- and middle-income countries have a difficult time acquiring and distributing them. Plant-derived vaccines can be stored by harvesting and freeze-drying the leaves. They may help solve the problem of global vaccine distribution. Vaccines are the mainstay of the efforts to que
Grand Reveal Tesla CEO Elon Musk finally made good on a big promise he'd made at the beginning of the year : that the Tesla Model S Plaid would be able to play the notoriously graphics-intensive game " Cyberpunk 2077 ." Now, half a year later, Musk briefly showed off the vehicle's onboard infotainment console running the game, as spotted by The Verge . During a livestreamed demo event , Musk comp
Through the biological fixation of the element nitrogen by the enzyme nitrogenase, organisms gain access to molecular nitrogen (N2) in the Earth's atmosphere, which is essential for building cellular structures. In addition, a vanadium-dependent variant of nitrogenase can reduce the toxic gas carbon monoxide (CO) to hydrocarbons. These reductions of N2 and CO are among the most important processes
Quantum coherence is a key ingredient of many fundamental tests and applications in quantum technology, including quantum communication, imaging, computing, sensing and metrology. However, the transfer of quantum coherence in free-space has so far been limited to direct line-of-sight channels, as atmospheric turbulence and scattering degrade the quality of coherence severely.
Since discovering the Higgs boson in 2012, the ATLAS Collaboration at CERN has been working to understand its properties. One question in particular stands out: why does the Higgs boson have the mass that it does? Experiments have measured its mass to be around 125 GeV—yet the Standard Model implies it has much larger mass and requires a very large correction to the mathematics in order to align t
Junior members of the workforce, including Generation Z, are facing digital burnout. 41 percent of workers globally are thinking about handing in their notice, according to a new Microsoft survey. A hybrid blend of in-person and remote work could help maintain a sense of balance – but bosses need to do more. More than half of 18 to 25 year-olds in the workforce are considering quitting their job.
As NASA continues plans for multiple commercial deliveries to the moon's surface per year, the agency has selected three new scientific investigation payload suites to advance understanding of Earth's nearest neighbor. Two of the payload suites will land on the far side of the moon, a first for NASA. All three investigations will receive rides to the lunar surface as part of NASA's Commercial Luna
The US Food and Drug Administration (FDA) recently approved aducanumab , the first new Alzheimer's disease medication to given the honor in 18 years. But, raining on that parade, three of the scientists from the agency's independent advisory panel have already resigned in protest of its approval. The experts say the clinical data on the drug that they reviewed was far too flimsy to justify the dr
Clinical trials have never been more in the public eye than in the past year, as the world watched the development of vaccines against covid-19, the disease at the center of the 2020 coronavirus pandemic. Discussions of study phases, efficacy, and side effects dominated the news. The most distinctive feature of the vaccine trials was their speed. Because the vaccines are meant for universal distr
Smaller firms are developing most antibiotics targeting superbugs but often at risk of bankruptcy Small drugmakers and biotech firms that are developing the bulk of new antibiotics need far more financial support, according to a new report, which warned that without these life-saving medicines there could be a pandemic of drug-resistant infections, worse than Covid-19. The Access to Medicine Foun
A long-held goal by chemists across many industries, including energy, pharmaceuticals, energetics, food additives and organic semiconductors, is to imagine the chemical structure of a new molecule and be able to predict how it will function for a desired application. In practice, this vision is difficult, often requiring extensive laboratory work to synthesize, isolate, purify and characterize ne
For decades, the ice shelf helping to hold back one of the fastest-moving glaciers in Antarctica has gradually thinned. Analysis of satellite images reveals a more dramatic process in recent years: From 2017 to 2020, large icebergs at the ice shelf's edge broke off, and the glacier sped up.
At the center of our Milky Way lies a supermassive black hole (SMBH) called Sagittarius A* (SgrA*). Supermassive black holes reside at the centers of most galaxies, and when they actively accrete gas and dust onto their surrounding hot disks and environments, they radiate across the electromagnetic spectrum. The mass of SgrA* is about 4 million solar masses, much smaller than the billions of solar
On Earth right now, there are about 10 trillion gigabytes of digital data, and every day, humans produce emails, photos, tweets, and other digital files that add up to another 2.5 million gigabytes of data. Much of this data is stored in enormous facilities known as exabyte data centers (an exabyte is 1 billion gigabytes), which can be the size of several football fields and cost around $1 billion
Northwestern Medicine scientists have invented a new method for resolving rearranged chromosomes and their 3D structures in cancer cells, which can reveal key gene regulators that lead to the development of tumors, published in Nature Methods.
Can you imagine one day using a telescope as thin as a sheet of paper, or a much smaller and lighter high-performance camera? Or no longer having that camera bump behind your smartphone? In a paper published in Nature Communications, researchers from the University of Ottawa have proposed a new optical element that could turn these ideas into reality by dramatically miniaturizing optical devices,
Taskforce chief Kate Bingham gets damehood and Oxford research leaders also rewarded Key figures in the battle against Covid-19 and Britain's vaccine success have been rewarded in the Queen's birthday honours list, with vaccines taskforce chair Kate Bingham getting a damehood. Honours are also bestowed on two leaders of the research teams at the Oxford Vaccine Centre who developed and manufacture
Modular construction involves building the components of a habitable structure in a factory, and then assembling those components on-site. The history of modular construction stretches back centuries, and it became briefly popular in the U.S. after World War II, but it's never quite caught on. Construction firms like iMod Structures, which constructs buildings that can be modified and relocated,
Using an ultrafast transmission electron microscope, researchers from the Technion—Israel Institute of Technology have, for the first time, recorded the propagation of combined sound and light waves in atomically thin materials.
The demand for flexible wearable electronics has spiked with the dramatic growth of smart devices that can exchange data with other devices over the internet with embedded sensors, software, and other technologies. Researchers consequently have focused on exploring flexible energy storage devices, such as flexible supercapacitators (FSCs), that are lightweight and safe and easily integrate with ot
Biodegradable microspheres can be used to deliver heart cells generated from stem cells to repair damaged hearts after a heart attack, according to new findings by UCL researchers. This type of cell therapy could one day cure debilitating heart failure, which affects an estimated 920,000 people in the UK and continues to rise as more people are surviving a heart attack than ever before.
A s Boris Johnson prepares to host Joe Biden and the leaders of the world's other G7 democracies this weekend, Britain appears to have recovered something of its old self. After years of stasis, slump, and division culminating in last year's catastrophic COVID-19 response, the country can legitimately count itself in a vanguard of powers leading the globe out of the pandemic. And yet, when compar
The world is at a crossroads, as humanity tries to mitigate climate change and halt biodiversity loss, while still securing a supply of food for everyone. A recent study in Nature Communications shows that global demands for commodities, especially in connection with agricultural development, are the main drivers of land use change in the global south.
A new study, published now in Nature Ecology and Evolution, draws on pollen records from tropical regions formerly claimed by the Spanish Empire in both the Atlantic and the Pacific to test the significance and extent of forest regrowth following widespread mortality among Indigenous populations after European contact in the 15th and 16th centuries. By analyzing microscopic pollen grains preserved
Although scientists often assume that random variations in scientific data fit symmetrical, bell-shaped normal distributions, nature isn't always so tidy. In some cases, a skewed distribution, like the log-normal probability distribution, provides a better fit. Researchers previously found that primary production by ocean phytoplankton and carbon export via particles sinking from the surface are c
Robert Koch proved that microbes cause infectious diseases and famously identified the etiological agents of anthrax, tuberculosis, and cholera. Louis Pasteur proved that life does not spontaneously generate from non-living material, made a significant advance in chemistry, invented pasteurization, and revolutionized vaccines. Koch and Pasteur had a bitter rivalry over the invention of the anthra
Researchers from Aarhus University and University of Copenhagen have developed a new method, which makes CRISPR gene editing more precise than conventional methods. The method selects the molecules best suited for helping the CRISPR-Cas9 protein with high-precision editing at the correct location in our DNA, the researchers explain.
At night, seven-year-old Miguel likes talking to his father Cesar Rubio about planets and stars. "I try to nurture that," says Rubio, a machinist in Pomona, California, who makes parts for mining and power generation equipment.
Whoopsie-Daisy Uber just accidentally played a cruel bait-and-switch on a portion of its drivers by erroneously offering healthcare to drivers before yanking it away. The rideshare company refuses to provide healthcare benefits to its drivers outside of California, Motherboard reports , so it was probably a pleasant surprise when drivers in other states got an email with the subject line "It's a
The research team led by Monica Gori at the IIT- Istituto Italiano di Tecnologia has recently published a study, which shows for the first time how children aged from 3 to 5 years old have problems in recognising the emotions of people wearing surgical masks. This collateral effect of the preventive measures linked to the Covid-19 health emergency could influence the correct development of childre
Multiple companies are working on new aerial modes of transportation, be they taxis that fly , drones that drive , or cars that drive and fly . What most of these vehicles have in common is that they're intended for just a few people to ride in at once, like airborne Ubers. But a New York-based startup is thinking bigger, quite literally: Kelekona is developing an electric vertical takeoff and la
Digital transformation has long been a well-established strategic imperative for organizations globally. The effects of covid-19—which have transformed the world into a (perhaps permanently) dispersed collection of individual broadband-connected consumers, partners, and employees—have not disrupted or wholly redefined this trend, instead they have created additional emphasis on digital transforma
New emails show that the CDC accepted input on February school reopening guidelines from the American Federation of Teachers, a powerful teachers union. Was that undue political influence — as some Republican lawmakers say — or just a routine process of consulting stakeholders?
Colorado has reported its first litter of gray wolf pups in 80 years, a major milestone in the US state's efforts to reintroduce the iconic species even as it stands imperiled in other parts of the country.
A new review of a famous study on declining sperm counts finds several flaws. The old report makes unfounded assumptions, has faulty data, and tends toward panic. The new report does not rule out that sperm counts are going down, only that this could be quite normal. Several years ago, a meta-analysis of studies on human fertility came out warning us about the declining sperm counts of Western me
Researchers identify the molecular mechanism for the anti-inflammatory activity of diabetes drug metformin and, in mouse studies, say it prevents lung inflammation in animals infected with SARS-CoV-2, the virus that causes COVID-19.
For the past few years, Annabelle Singer and her collaborators have been using flickering lights and sound to treat mouse models of Alzheimer's disease, and they've seen some dramatic results. Now they have results from the first human feasibility study of the flicker treatment, and they're promising. "We looked at safety, tolerance, and adherence, and several different biological outcomes, and t
A team of scientists at the University of Sussex have for the first time built a modular quantum brain scanner, and used it to record a brain signal. This is the first time a brain signal has been detected using a modular quantum brain sensor anywhere in the world. It's a major milestone for all researchers working on quantum brain imaging technology because modular sensors can be scaled up, like
Scientists have developed a new technique using phosphonium salts that can help drive the future production of green ammonia. This process could reduce the impact of ammonia production on global carbon emissions. Each metric ton of ammonia produced today contributes to roughly 1.9 metric tons of greenhouse emissions.
On June 1, NASA's Perseverance Mars rover kicked off the science phase of its mission by leaving the "Octavia E. Butler" landing site. Until recently, the rover has been undergoing systems tests, or commissioning, and supporting the Ingenuity Mars Helicopter's month of flight tests.
The enormous potential of Big Data has already been demonstrated in areas such as financial services and telecommunications. An international team of researchers led by the IPK Leibniz Institute has now tapped the potential of big data for the first time on a large scale for plant research. To this end, data from three projects were used to increase the predictive accuracy for yield in hybrid vari
Observers in north America and Europe were able to witness a morning solar eclipse, as the moon passed between the Earth and the sun. While those in Canada, Greenland and northern Russia were treated to an annular eclipse, creating a 'ring of fire', skygazers elsewhere saw a partial eclipse, creating a crescent sun Solar eclipse 2021: spectacle visible across UK and Ireland Continue reading…
A team of archaeologists from the Hebrew University of Jerusalem (HU) made a rare discovery when they unearthed a small clay seal impression dating back some 7000 years. The impression, with two different geometric stamps imprinted on it, was discovered in Tel Tsaf, a prehistoric village located in Israel's northern Beit She'an Valley.
X-ray free electron laser (XFEL) crystallography could revolutionize mechanistic studies of photosystem II (PSII) by providing three-dimensional structures of its reaction intermediates that cannot be obtained using traditional crystallographic techniques. However, care must be taken to ensure that the XFEL data are interpreted correctly. Here, we challenge the conclusion that…
Hypertrophic cardiomyopathy (HCM) is the most common inherited form of heart disease, associated with over 1,000 mutations, many in β-cardiac myosin (MYH7). Molecular studies of myosin with different HCM mutations have revealed a diversity of effects on ATPase and load-sensitive rate of detachment from actin. It has been difficult to…
Superelastic materials capable of recovering large nonlinear strains are ideal for a variety of applications in morphing structures, reconfigurable systems, and robots. However, making oxide materials superelastic has been a long-standing challenge due to their intrinsic brittleness. Here, we fabricate ferroelectric BaTiO3 (BTO) micropillars that not only are superelastic but…
Wang et al. (1) performed their own analysis of our crystallographic data (2) and questioned our, and similar previous (3–5), results that a newly inserted water (Ox) in the catalytic center of photosystem II (PSII) can be uniquely identified in the room temperature crystal structures taken at various time points…
The frequency distributions can characterize the population-potential landscape related to the stability of ecological states. We illustrate the practical utility of this approach by analyzing a forest–savanna model. Savanna and forest states coexist under certain conditions, consistent with past theoretical work and empirical observations. However, a grassland state, unseen in…
Environmental fluctuations are a common challenge for single-celled organisms; enteric bacteria such as Escherichia coli experience dramatic changes in nutrient availability, pH, and temperature during their journey into and out of the host. While the effects of altered nutrient availability on gene expression and protein synthesis are well known, their…
Short liquid bridges are stable under the action of surface tension. In applications like electronic packaging, food engineering, and additive manufacturing, this poses challenges to the clean and fast dispensing of viscoelastic fluids. Here, we investigate how viscoelastic liquid bridges can be destabilized by torsion. By combining high-speed imaging and…
Wings that can vary their shapes as freely as birds' wings could have advantages for small aircraft in built environments, a new study suggests. Researchers found that wings that can morph in continuous 3D shapes could help keep drones stable in gusts of wind and perhaps help them land in tighter spaces. "These are just two uses that we identified, but another part that makes me really excited is
Scientists found that the ability to fly is embedded in birds' spinal cords. The team closely examined the neural networks of chicken and mice embryos and discovered that the genetic coding of the ephrin-B3 molecule in birds is fundamentally different than those of mammals and reptiles.
Lab animals deficient in vitamin D crave and become dependent on opioids, which is curbed when normal levels of the vitamin are restored. Human health records indicate that people with low vitamin D are more likely to use and misuse opioids. Study results suggest a potential role for vitamin D supplementation in fighting opioid addiction.
The role of juxtaposition of activating and inhibitory receptors in signal inhibition of cytotoxic lymphocytes remains strongly debated. The challenge lies in the lack of tools that allow simultaneous spatial manipulation of signaling molecules. To circumvent this, we produced a nanoengineered multifunctional platform with molecular-scale spatial control of ligands, which was applied to elucidate
Currently, high-throughput approaches are lacking in the isolation of antibodies with functional readouts beyond simple binding. This situation has impeded the next generation of cancer immunotherapeutics, such as bispecific T cell engager (BiTE) antibodies or agonist antibodies against costimulatory receptors, from reaching their full potential. Here, we developed a highly efficient droplet-base
The current opioid epidemic warrants a better understanding of genetic and environmental factors that contribute to opioid addiction. Here we report an increased prevalence of vitamin D (VitD) deficiency in patients diagnosed with opioid use disorder and an inverse and dose-dependent association of VitD levels with self-reported opioid use. We used multiple pharmacologic approaches and genetic mo
Skin cancer is one of the most common types of cancer in the United States and worldwide. Topical products are effective for treating cancerous skin lesions when surgery is not feasible. However, current topical products induce severe irritation, light-sensitivity, burning, scaling, and inflammation. Using hyaluronic acid (HA), we engineered clinically translatable polymer-drug conjugates of doxo
Does contact across social groups influence sociopolitical behavior? This question is among the most studied in the social sciences with deep implications for the harmony of diverse societies. Yet, despite a voluminous body of scholarship, evidence around this question is limited to cross-sectional surveys that only measure short-term consequences of contact or to panel surveys with small samples
Genome-embedded ribonucleotides arrest replicative DNA polymerases (Pols) and cause DNA breaks. Whether mammalian DNA repair Pols efficiently use template ribonucleotides and promote RNA-templated DNA repair synthesis remains unknown. We find that human Pol reverse transcribes RNA, similar to retroviral reverse transcriptases (RTs). Pol exhibits a significantly higher velocity and fidelity of deo
Molecular evolutionary time scales are expected to predate the fossil evidence, but, particularly for major evolutionary radiations, they can imply extremely protracted stem lineages predating the origin of living clades, leading to claims of systematic overestimation of divergence times. We use macroevolutionary birth-death models to describe the range of total-group and crown-group ages expecte
Anisogamy, the size difference between small male and large female gametes, is known to enable selection for sexual dimorphism and behavioral differences between sexes. Nevertheless, even isogamous species exhibit molecular asymmetries between mating types, which are known to ensure their self-incompatibility. Here, we show that different properties of the pheromones secreted by the MAT a and MAT
The southern boundary (SB) of the Antarctic Circumpolar Current, the southernmost extent of the upper overturning circulation, regulates the Antarctic thermal conditions. The SB's behavior remains unconstrained because it does not have a clear surface signature. Revisited hydrographic data from off East Antarctica indicate full-depth warming from 1996 to 2019, concurrent with an extensive polewar
The potential of big data to support businesses has been demonstrated in financial services, manufacturing, and telecommunications. Here, we report on efforts to enter a new data era in plant breeding by collecting genomic and phenotypic information from 12,858 wheat genotypes representing 6575 single-cross hybrids and 6283 inbred lines that were evaluated in six experimental series for yield in
Contractile injection systems (CISs) [type VI secretion system (T6SS), phage tails, and tailocins] use a contractile sheath-rigid tube machinery to breach cell walls and lipid membranes. The structures of the pre- and postcontraction states of several CISs are known, but the mechanism of contraction remains poorly understood. Combining structural information of the end states of the 12-megadalton
In the developing embryos, the cortical polarity regulator Par-3 is critical for establishing Notch signaling asymmetry between daughter cells during asymmetric cell division (ACD). How cortically localized Par-3 establishes asymmetric Notch activity in the nucleus is not understood. Here, using in vivo time-lapse imaging of mitotic radial glia progenitors in the developing zebrafish forebrain, w
Speedup of Pine Island Glacier over the past several decades has made it Antarctica's largest contributor to sea-level rise. The past speedup is largely due to grounding-line retreat in response to ocean-induced thinning that reduced ice-shelf buttressing. While speeds remained fairly steady from 2009 to late 2017, our Copernicus Sentinel 1A/B–derived velocity data show a >12% speedup over the pa
Chromatin structure is critical for gene expression and many other cellular processes. In Arabidopsis thaliana , the floral repressor FLC adopts a self-loop chromatin structure via bridging of its flanking regions. This local gene loop is necessary for active FLC expression. However, the molecular mechanism underlying the formation of this class of gene loops is unknown. Here, we report the chara
Automating the molecular design-make-test-analyze cycle accelerates hit and lead finding for drug discovery. Using deep learning for molecular design and a microfluidics platform for on-chip chemical synthesis, liver X receptor (LXR) agonists were generated from scratch. The computational pipeline was tuned to explore the chemical space of known LXRα agonists and generate novel molecular candidat
Oxygenic photosynthesizers (cyanobacteria and eukaryotic algae) have repeatedly become endosymbionts throughout evolution. In contrast, anoxygenic photosynthesizers (e.g., purple bacteria) are exceedingly rare as intracellular symbionts. Here, we report on the morphology, ultrastructure, lifestyle, and metagenome of the only "purple-green" eukaryote known. The ciliate Pseudoblepharisma tenue harb
Space radiation may cause DNA damage to cells and concern for the inheritance of mutations in offspring after deep space exploration. However, there is no way to study the long-term effects of space radiation using biological materials. Here, we developed a method to evaluate the biological effect of space radiation and examined the reproductive potential of mouse freeze-dried spermatozoa stored
Flight in birds evolved through patterning of the wings from forelimbs and transition from alternating gait to synchronous flapping. In mammals, the spinal midline guidance molecule ephrin-B3 instructs the wiring that enables limb alternation, and its deletion leads to synchronous hopping gait. Here, we show that the ephrin-B3 protein in birds lacks several motifs present in other vertebrates, di
The opportunistic pathogen, Pseudomonas aeruginosa , a flagellated bacterium, is one of the top model organisms for biofilm studies. To elucidate the location of bacterial flagella throughout the biofilm life cycle, we developed a new flagella biotracking tool. Bacterial flagella were site-specifically labeled via genetic code expansion. This enabled us to track bacterial flagella during biofilm
The revolutionizing efficacy of recombinant human bone morphogenetic protein (rhBMP-2) for clinical spinal fusion is hindered by safety issues associated with the high dose required. However, it continues to be widely used, for example, in InFUSE Bone Graft (Medtronic). Here, we developed a translational protein engineering–based approach to reduce the dose and thereby improve the safety of rhBMP
Though the coronavirus continues to spread around the world, the end appears to be in sight in the United States. And with that hopeful end, this will mark the last episode of Social Distance . James Hamblin, Maeve Higgins, and returning co-host Katherine Wells gather to say goodbye to the show, reflect on what we've learned these past 15 months, and listen to voicemails from past guests. Listen
Carried like stowaways in the guts of international travelers, new and potentially deadly strains of antimicrobial resistant superbugs may be coming to a community near you, according to a new study. "Even before the COVID-19 pandemic, we knew that international travel was contributing to the rapid global increase and spread of antimicrobial resistance," says Alaric D'Souza, an MD/PhD student at
Det är inte bara virus som sprids i kluster. Även sociala normer. Det konstaterar Kungliga vetenskapsakademien i en ny rapport. När människor använder munskydd ökar chanserna för att ännu fler ska ta efter och göra likadant. Vi är också mer benägna att vaccinera oss om olika ledargestalter går före och offentligt tar vaccin.
Ju varmare det blir, desto viktigare blir det att vattna på rätt sätt med rätt mängd i rätt tid – utan att slösa på vattnet som resurs. Forskare bygger på system som ska göra det enklare för jordbrukarna. I framtiden kommer det bli allt viktigare att ta hänsyn till sambandet mellan vatten, energi och mat för att säkra tillgång till livsmedel, både i Sverige och globalt. Begreppet "vatten-energi-m
I am curious to know what you guys think could or would happen in the 2060s and 2070s. I am asking this mainly because I see people talking about potential future events in the 2040s and 2050s but that doesn't seem to apply to the decades of the 2060s and 2070s. Anyways, I look forward to what you have to say. submitted by /u/Grand-Daoist [link] [comments]
Ledande personer ur ursprungsbefolkningen på Nya Zeeland kan ha varit först med att upptäcka Antarktis – redan på 700-talet. En ny studie riskerar att ställa den officiella historieskrivningen, enligt vilken kontinenten upptäcktes först ett millennium senare, på ända.
If you have trouble falling asleep, problems remembering or concentrating are likely to occur more than a decade later, according to new research. Trouble sleeping was the only symptom that predicted poor cognitive performance 14 years later when compared with other symptoms of insomnia, the study shows. There is growing evidence linking insomnia and cognitive impairment in older adults, but inte
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Nature, Published online: 11 June 2021; doi:10.1038/d41586-021-01559-x Scientists praise the budget boost slated for the National Science Foundation, but worry the legislation could dampen international collaborations.
Pairing sky-mapping algorithms with advanced immunofluorescence imaging of cancer biopsies, researchers developed a robust platform to guide immunotherapy by predicting which cancers will respond to specific therapies targeting the immune system.
Leaders who encourage their employees to learn on the job and speak up with ideas and suggestions for change have teams that are more effective and resilient in the face of unexpected situations, according to new research.
Researchers have published a first- of-its-kind study that shows that near-infrared (NIR) spectrum cameras can help python hunters more effectively track down these invasive snakes, especially at night.
On Monday, the FDA approved the use of a new Alzheimer's drug called aducanumab, developed by the pharmaceutical company Biogen. Whether the drug works remains contested, and the approval decision has set off a fierce debate over the ways that commerce and advocacy might influence which drugs reach market.
Preclinical trials of a new radiopharmaceutical to treat ovarian cancer have produced successful results, dramatically limiting tumor growth and decreasing tumor mass. Designed specifically for ovarian cancers that are resistant to traditional therapies, the new radiopharmaceutical can be produced in 25 minutes at low cost, which leads to better efficiency compared with alternative methods. This r
Researchers examined the associations between Medicare Advantage star ratings, which are created using data from all enrollees in a plan, and disparities in care for racial/ethnic minorities and enrollees with lower income and less education.
What The Study Did: International medical graduates often practice as physicians in locations and specialties less preferred by U.S. medical graduates. This study reports on physician mortality from COVID-19, and on the mortality of international medical graduates in particular.
Peter Turnley / Corbis / Getty When the psychologist Michael Reichert became a father to sons, he aimed to avoid putting his boys into narrow masculine boxes, an effort that he details in his book, How to Raise a Boy . Still, he sometimes slipped. For example, in a 2019 Atlantic interview, Reichert recalled forcing his young son to face off against bullies rather than offering him a refuge. "I ha
Research suggests that children with average risk medulloblastoma can receive radiation to a smaller volume of the brain at the end of a six-week course of treatment and still maintain the same disease control as those receiving radiation to a larger area. But the dose of preventive radiation treatments given to the whole brain and spine over the six-week regimen cannot be reduced without reducing
If you've sanded down your edges to fit in, it's time to bring them back — there's power, value and beauty there, says Crystal Rasmussen. With candor and humility, Rasmussen shares their experience navigating shame, how it manifests in ourselves and the world and the ways drag revealed a path toward self-love and acceptance. A talk for anyone struggling with becoming exactly who they're meant to
The widely studied metallic asteroid known as 16 Psyche might not be as metallic or dense as once thought, researchers report. The asteroid was long thought to be the exposed iron core of a small planet that failed to form during the earliest days of the solar system. The new hint at a much different origin story. Scientists are interested in 16 Psyche because if its presumed origins are true, it
Transportation infrastructure, such as roads and railway systems, is one of the sectors most threatened by climate change. Extreme weather events—such as flooding, sea level rises and storm surges—repeatedly wreak havoc on transport networks.
Researchers have identified a previously unknown early driver of Alzheimer's disease (AD) and vascular dementia (VaD). They report high levels of cis P-tau, a pathogenic protein, in human AD and VaD brains as well as preclinical disease models. Treatment with an antibody to the toxic protein prevented disease progression and reversed disease symptoms and restored cognitive function in older mice.
Most people listen to music throughout their day and often near bedtime to wind down. But can that actually cause your sleep to suffer? When a sleep researcher realized he was waking in the middle of the night with a song stuck in his head, he saw an opportunity to study how music — and particularly stuck songs — might affect sleep patterns.
Much like a supply truck crossing the countryside, the misfolded proteins that damage neurons in Alzheimer's disease travel the 'roads' of the brain, sometimes stopping and sometimes re-routing to avoid roadblocks.
Plant functional traits are morphological, physiological or phenological properties that affect plant growth, survival, and reproduction. They hold the promise to explain plant species distribution patterns. However, few studies have linked multiple traits to multiple niche dimensions (i.e., light, water, and nutrients).
Most researchers can draw a line from their current field of study to something in their past that first lit the spark—an engineer who had a knack for fixing things, an economics professor who was always good with numbers.
Shifts in weather patterns induced by climate change will increase extreme heat and reduce rainfall across major crop growing regions, with impacts on agricultural production. Will this trigger a decline in the supply of calories needed to sustain the world's growing population?
ESA's large-class science missions for the timeframe 2035-2050 will focus on moons of the giant Solar System planets, temperate exoplanets or the galactic ecosystem, and new physical probes of the early universe.
An important element for the protection of biodiversity is the willingness of the public to support restoration efforts. Using a longitudinal survey design with 1,000 respondents each in France, Germany, Norway and Sweden, scientists led by the Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB) investigated which values, beliefs and norms promote conservation-oriented behavior towa
Although COVID-19 vaccines offer relief from some of the risks and worries of the past 18 months, parents with young children find themselves in a delicate gray zone. "One of the hardest parts about being a parent right now is feeling like even though you're vaccinated and ready to celebrate that, you're still living with one foot in the unvaccinated world," says Keri Althoff , an epidemiologist
Climate change is causing mountain snow to melt more rapidly and glaciers to shrink, but this is making a widely varied impact on water supplies in Asia, a new paper by PSI Senior Scientist Jeffrey Kargel says.
About five years ago, Areg Danagoulian, associate professor in the MIT Department of Nuclear Science and Engineering (NSE), became intrigued by a technique developed by researchers at Los Alamos National Laboratory that uses a neutron beam to identify unknown materials.
Cone snails are deadly sea predators; their venom can kill fish and even humans. But chemical biologist Mandë Holford says that powerful venom can actually be used for good — to treat human diseases. (Image credit: Courtesy of TED)
Marine biologist Ayana Elizabeth Johnson is obsessed with one research subject — the parrot fish. She says there is urgent work to be done to save them and their home, the coral reefs. (Image credit: Ryan Lash / TED)
Marine biologist Marah Hardt is fascinated with the mating habits of marine life. If we want to save the oceans, she says we have to understand the weird and whimsical sex that helps populate it. (Image credit: Courtesy of TED)
With Oskar Aszmann and his team at the Department of Plastic, Reconstructive and Aesthetic Surgery, MedUni Vienna has long been regarded as a world leader in bionic limb reconstruction. It was only last year that the world's first fully integrated bionic arm prosthesis was developed at MedUni Vienna. This is ready-to-use and is described as "Plug and Play." Although all bionic aids have so far bee
UC San Diego School of Medicine researchers discovered gene expression patterns associated with pandemic viral infections, providing a map to help define patients' immune responses, measure disease severity, predict outcomes and test therapies — for current and future pandemics.
Catherine Mohr shares the story of a scuba diving trip gone wrong, where getting stabbed by a sea urchin transformed her relationship with the ocean… and ultimately led her to the love of her life. (Image credit: Courtesy of Catherine Mohr)
A cardiac MRI of college athletes who had COVID-19 is seven times more effective in detecting inflammation of the heart than symptom-based testing, according to a new study. The study of 1,597 COVID-19 positive athletes in the Big Ten Conference who had cardiac magnetic resonance (CMR) screening found 2.3% were diagnosed with myocarditis and most didn't exhibit symptoms of the rare disease, a lea
A new study has identified mechanisms by which COVID-19 can lead to Alzheimer's disease-like dementia. The findings indicate an overlap between COVID-19 and brain changes common in Alzheimer's, and may help inform risk management and therapeutic strategies for COVID-19-associated cognitive impairment.
Researchers used a hydraulic model to consider the degree to which human-caused climate change may have affected flooding in Houston in 2017 during Hurricane Harvey. Resources were used to quantify the increase in Houston flood area and depth and to host a portal where other scientists and the public can access and explore the resulting data.
Scientists at the University of Oxford have discovered that classical nova explosions are accompanied by the ejection of jets of oppositely directed hot gas and plasma, and that this persists for years following the nova eruption. Previously, such jets had only been encountered emanating from very different systems such as black holes or newly collapsing stars.
A body found buried in a ditch by construction workers in the village of Great Casterton, in the east Midlands of England, has shed new light on Roman slavery in Britain. A new analysis of the skeleton and the burial has revealed that the male body was probably that of slave from third century.
Frogs have been around for about 140 million years, since dinosaurs roamed the Earth, and are found in most moist corners of the world. IUCN has assessed 6,340 species of these tailless and smooth-bodied amphibians, and almost one in ten of them are classified as Critically Endangered.
Every weekday evening, our editors guide you through the biggest stories of the day, help you discover new ideas, and surprise you with moments of delight. Subscribe to get this delivered to your inbox. The right to vote in America is under assault, and Democrats may be botching their best chance to fight back. On the state level, Republicans continue to back a wave of voter-suppression laws. As
The annual number of new HIV infections among men who have sex with men in England is likely to have fallen dramatically, from 2,770 in 2013 to 854 in 2018, showing elimination of HIV transmission by 2030 to be within reach — suggests new work.
New research identifies a factor that may let the fungus Candida albicans "shape-shift." As the fungus grows, it can multiply as single, oval-shaped cells called yeast or propagate in an elongated form called hypha, consisting of thread-like filaments. This dual nature can help the pathogen survive in the body, where it can cause disease, including dangerous hospital-acquired infections. In a stu
Plastics are very useful materials. They've contributed significant benefits to modern society. But the unprecedented amount of plastics produced over the past few decades has caused serious environmental pollution.
Social media offers many benefits to Indigenous peoples, such as ways to establish and navigate identity, build and maintain strong connections to family and community, and seek and offer mutual support. While there are these positive experiences, many people also report having negative encounters online.
A new international study has cast doubts on the view that variations in the density of some of the deepest currents of the subpolar North Atlantic Ocean are caused by winter surface conditions and represent changes in the strength of the Meridional Overturning Circulation (MOC).
A former endowed professor at the University of Kentucky has resigned from the faculty days before a committee at the institution was scheduled to vote on whether to fire him for misconduct, Retraction Watch has learned. In 2018, the university began investigating Xianglin Shi, a toxicologist and cancer biologist who that year, as we reported … Continue reading
Nature, Published online: 10 June 2021; doi:10.1038/d41586-021-01589-5 Cases of dengue fever plummeted in a trial of modified virus-resistant mosquitoes. Plus, four urgent questions about long COVID and clues to the mysterious origins of fast radio bursts.
Earth's atmosphere has a budget, and when expenses outpace savings, secondary aerosols form in areas of excessive pollution. Greenhouse gases enter the atmosphere, and free radicals bond to the molecules, rendering them inert. But when there are more pollution molecules than free radicals, they are left to recombine and form ozone and visible particulate matter—smog and haze.
There are uncountable mysteries in the universe, some of which may require the work of future generations to solve. Others we might be able to unravel in the not-too-distant future. For example, scientists are zeroing in on fast radio bursts, or FRBs. These anomalous pulses of energy were discovered in 2007, and a new data set covering hundreds of FRBs is being made available. This could be the a
Alkaline zinc-iron flow batteries (AZIFB) are suitable for stationary energy storage applications due to advantages of high open-cell voltage, low cost, and environmental friendliness. However, they suffer from zinc dendrite accumulation and relatively low operation current density.
It's as true now as it's ever been: You never know what's going to happen tomorrow. You can't prevent the worst from happening, but you can make sure you and everyone else in your household is prepared for whatever is coming around the next bend with a Judy Kit survival kit , available in your choice of four different bundles that pack a wealth of different survival goods into one accessible pack
Long-term water security is essential for the future of Texas, and the state acutely needs a common law system that can balance world-scale agricultural activity, industrial development and urban growth while also protecting private property rights, according to new research from Rice University's Baker Institute for Public Policy and Texas State University's The Meadows Center for Water and the E
As the visual evidence of climate change continues to shine a glaring light on a huge problem around the globe, scientists studying at several National Science Foundation (NSF) Long Term Ecological Research (LTER) sites are tackling the issue in part by examining long-term changes in the diversity and abundance of small mammals to understand their vulnerabilities to climate change.
Researchers from Hokkaido University have successfully developed a new method to give luminescent properties to generic polymers, such as polystyrene and polyethylene. The technique, which was published in the journal Angewandte Chemie International Edition, makes it possible to easily prepare luminescent polymers without using complicated organic synthetic methods.
Researchers analysing skeletal remains in the city of Cambridge find a dramatic increase in 'hallux valgus' around the time that pointed shoes became de rigueur in the 1300s. They also uncover a link between this minor deformity and increased risk of fractures.
Researchers have identified how tumors cause immune cells to lose their ability to fight cancer, by producing harmful fats the energy-hungry immune cells ingest, impairing their functionality. The understanding opens new avenues for novel immunotherapies for cancer.
Vad vore en svensk sommar utan Sommar i P1. Här är årets sommarvärdar med kopplingar till forskarvärlden: 4 juli Mikael Dolsten forskningschef Pfizer och läkare som bland annat ska prata om arbetet med att ta fram ett vaccin mot covid-19.
Google reports that it is now using AI to build its future Tensor Processing Units. The company has published some work in this area about a year ago, but today's announcement indicates the technology has matured. Alexis Mirhoseini led the project. The semiconductor industry has invested in various tools that automate parts of the design process for decades. Back when a CPU had 10,000 to 100,000
The virus that causes COVID-19 can infect and replicate in human kidney cells, but this does not typically lead to cell death. Kidney cells that already have features of injury may be more easily infected and develop additional injury.
As we learn more about the body, hormones are offering new insights into not just how we become adults, but how we gain or lose weight, our fertility, and even how we age . Understanding your hormonal balance now can help you plan for the future, so the Modern Fertility Hormone Test makes it easy to learn about your fertility easily, safely, and privately. Rated Fast Company's number one healthca
How does our gut respond and adapt to changing conditions? Where does this fundamental and critical flexibility come from? Technion scientists are unraveling the genius of the gut's microbiome, through microbiota, all the way to genetic inversion.
While Germany, Italy and the United States will participate in the G7 summit as global leaders in green competitiveness, Australia will attend as a 'green laggard," according to a new global analysis published today involving Monash University.
Small business ownership is commonly thought to not only be a vehicle for financial stability and wealth building, but also a way to close the racial wealth gap. Small businesses are known to be a key component of the small business owner's financial wellbeing (Gentry and Hubbard 2004), but it is not at all clear from current evidence that small business ownership alone closes the wealth gap. In f
Spending on science worldwide increased (+19 percent) between 2014 and 2018, as did the number of scientists (+13.7 percent). This trend has been further boosted by the COVID crisis, according to UNESCO's new science report, "The Race against Time for Smarter Development."
In cultures that place a high value on conventional gender norms, particularly those that prize men as the breadwinners in a family, their unemployment plays an outsized role in whether a romantic relationship ultimately succeeds or fails.
A team of Northwestern Medicine investigators has discovered a set of intracellular mechanisms that support the polarized function of the skin's outermost layer, the epidermis, according to findings published in Current Biology.
Nyt lægemiddel viser særdeles lovende resultater hos patienter med en række medfødte blodsygdomme, som der i dag ikke findes gode behandlinger mod. Dansk overlæge bag studiet er meget positiv over resultaterne.
Though a seemingly worldwide practice, there is little plausibility and no evidence to support burping infants before, during, or after feeds. And it doesn't have anything to do with SIDS. The post first appeared on Science-Based Medicine .
Kræftcellerne, der ligger til grund for diagnosen mantle celle lymfom, er både meget forskellige fra patient til patient og formentlig også meget forskellige i deres genetiske udtryk fra celle til celle.
Hi together, I am asking myself what are trying to learn or get in a space to build knowledge and skills, that will payoff in the future? For Example: AI development I am really curiuos what you all think and which spaces I have probably not thought about:) submitted by /u/DaHongPao88 [link] [comments]
Healthcare, childcare, elder care. Probably some others I'm forgetting about. If you look at where the job growth is forecasted to be its in these, tech (including renewables), management and marketing. I wanted to ask specifically about care in this thread because people demand a high level of fidelity for interactions that close. So I imagine robot caregivers will be further out, although I thi
Visste ni att landslaget enfärgade gul-blå dräkt gjorde premiär i OS 1912? Och att Sverige spelat flest landskamper i världen? Fotbollsforskaren Torbjörn Andersson har dammsugit Sverige på prylar som berättar om blågult och Sveriges 130 år långa fotbollshistoria. – Mycket har slängts. Jag hoppas att man tar tillvara på det som finns kvar, och att även fotbollens historia ges en plats på våra muse
Scientific Reports, Published online: 11 June 2021; doi:10.1038/s41598-021-90969-y Allele frequencies of single nucleotide polymorphisms of clinically important drug-metabolizing enzymes CYP2C9 , CYP2C19 , and CYP3A4 in a Thai population
A journal has issued an expression of concern after learning that it may have published abstracts from meetings that appear not to have taken place. As many journals do, Basic & Clinical Pharmacology and Toxicology, a Wiley title, occasionally publishes meeting supplements. But according to the journal, it recently learned from several authors that a … Continue reading
En eksperimentel behandling har i forsøg med mus vist lovende resultater som potential behandling mod genfusioner ved akut myeloid leukæmi. Princippet kan også bruges ved andre kræftformer, siger dansk forsker.
Skogsindustrin är av tradition männens värld. En studie undersöker hur kvinnliga skogsägare agerar utifrån normer om vad som anses vara kvinnligt och manligt. Skogsproduktionen är manligt kodad – det är utgångspunkten i Emmeline Laszlo Ambjörnssons forskning. Genom intervjuer och observationer vill hon förstå hur kvinnliga skogsägare som deltar i egna nätverk agerar utifrån normer om vad som anse
Nature Communications, Published online: 11 June 2021; doi:10.1038/s41467-021-23852-z Previous research showed the existence of Rydberg excitons with large principle quantum numbers in Cu2O. Here, by using two-color pump-probe optical spectroscopy, the authors demonstrate the generation and control of long-range correlations between these giant Rydberg excitons, leading to exciton blockade.
Nature Communications, Published online: 11 June 2021; doi:10.1038/s41467-021-23819-0 The fast-growing interest for two-dimensional (2D) nanomaterials is undermined by their natural restacking tendency, which severely limits their practical application. Novel porous heterostructures that coordinate 2D nanosheets with monolayered mesoporous scaffolds offer an opportunity to greatly expand the libr
Nature Communications, Published online: 11 June 2021; doi:10.1038/s41467-021-23428-x O-GalNAc glycans are essential in many biological and pathological processes, but difficult to access due to their structural complexity and synthetic challenges. Here, the authors report an efficient chemoenzymatic modular assembly strategy to construct structurally diverse O-GalNAc glycans, use the synthesised
Nature Communications, Published online: 11 June 2021; doi:10.1038/s41467-021-23821-6 Here, the authors use simulated quantitative gut microbial communities to benchmark the performance of 13 common data transformations in determining diversity as well as microbe-microbe and microbe-metadata associations, finding that quantitative approaches incorporating microbial load variation outperform compu
Nature Communications, Published online: 11 June 2021; doi:10.1038/s41467-021-23666-z Cross-linking mass spectrometry (MS) can identify protein-protein interaction (PPI) networks but assessing the reliability of these data remains challenging. To address this issue, the authors develop and validate a method to determine the false-discovery rate of PPIs identified by cross-linking MS.
Nature Communications, Published online: 11 June 2021; doi:10.1038/s41467-021-23657-0 Progression of the cell division cycle requires feedback loops including those of phosphorylation and dephosphorylation; however the precise regulation of phosphorylation kinetics of Arpp19, an inhibitor of protein phosphatase 2A, is unclear. Here, the authors report that feedback between phosphorylation states
Nature Communications, Published online: 11 June 2021; doi:10.1038/s41467-021-23829-y Hippocampal place cells contribute to navigation and memory formation. Here, the authors use in vivo glutamate imaging to reveal patterns of excitatory input received by place cell dendrites and find more spatially tuned and functionally organized inputs arriving in the place field.
Nature Communications, Published online: 11 June 2021; doi:10.1038/s41467-021-23850-1 A major goal in Engineering Biology and Materials Science is the development of active, autonomous scaffolds that mimic those present in biological cells. Here the authors report a toolkit for programming the dynamic behaviour of nucleic acid scaffolds in minimal cell-like compartments.
In "Holding Back the River," Tyler J. Kelley offers a spirited tour of the nation's crucial waterways, and the crumbling structures built to control them. Sorely underfunded and outdated, many dams that provide flood control, irrigation, and transportation must be replaced — or reimagined.
Den schweiziske lægemiddelproducent Roche øjner et nyt marked til deres kræftmiddel Tecentriq inden for ikke-småcellet lungekræft, efter nye resultater præsenteret på ASCO viser signifikant forbedring af den sygdomsfri overlevelse med behandlingen. Overlæge glæder sig over resultaterne.
Att cykla till jobb och skola, även om man gör det bland avgaser, är en hälsovinst. Faktum är att effekterna man får av träning är extra betydelsefulla för den som bor i områden med mycket luftföroreningar. Att förmå pendlare att ställa bilen och ta cykeln ger en dubbel hälsovinst. Dels minskar avgaserna, dels förbättras hälsan för pendlarna själva. Även i områden med mycket luftföroreningar är f
Lægeforeningen vil med sit nye udspil 'Giv psykiatrien et langsigtet løft' gøre op med mange års underprioritering af psykiatrien og de alvorlige konsekvenser, det har haft for danskere med psykiske lidelser. »Psykiatrien er desværre et område, som politisk er kendetegnet ved mange års underprioritering, og ved en mangel på klart definerede målsætninger,« lyder det fra lægeformand.
PLUS. Skader på tarmbakterier forårsaget af underernæring overføres fra mødre til nyfødte og medfører alvorlige konsekvenser for børns udvikling, indikerer resultaterne fra et internationalt forskningsprojekt.
China's Chang'e-4 probe marked the first soft-landing of a spacecraft on the far side of the Moon, which always faces away from Earth. To communicate with ground stations, Chang'e-4 relies on Queqiao, a relay communication satellite that orbits a point behind the Moon and bridges Earth and Chang'e-4. In a recent review, researchers explain the design of Queqiao and depict the future of lunar relay
Frihet, självbestämmande och möjligheten att få leva ett liv som alla andra. Men också en ständigt överhängande rädsla att mista sitt stöd. I en ny studie har forskare undersökt vilken betydelse personlig assistans hade för människors levnadsvillkor i en tid när besparingskrav påverkade både politik och praxis.
Florida's state Board of Education banned "critical race theory" from public school classrooms Thursday, adopting new rules it said would shield schoolchildren from curricula that could "distort historical events."
Leaders who encourage their employees to learn on the job and speak up with ideas and suggestions for change have teams that are more effective and resilient in the face of unexpected situations, according to new research from Rice University and the University of Windsor.
Scientists at Tokyo Institute of Technology and NEC Corporation jointly develop a 28-GHz phased-array transceiver that supports efficient and reliable 5G communications. The proposed transceiver outperforms previous designs in various regards by adapting fast beam switching and leakage cancellation mechanism.
COVID-19-pandemien har haft stor indflydelse på mange arbejdspladser det seneste år. I almen praksis har en særaftale om telefonkonsultationer formentlig bragt den største forandring med sig med 100.000 ugentlige konsultationer over telefonen i snit. Aftalen ophørte 1. juni.
Det virker helt malplaceret, at det offentlige sundhedsvæsen, betalt af danskernes skattekroner, ikke har mere fokus på, om de metoder, der har vundet indpas gennem årene, rent faktisk er pengene værd.
Patient Reported Outcome (PRO) har uden tvivl et stort potentiale i det danske sundhedsvæsen, men kun hvis det bringes i anvendelse baseret på inddragelse af både patienter og klinikere. Det er den aktive kliniske anvendelse, som giver mening og mulighed for forløsning af PRO's potentiale.
For et halvt år siden tiltrådte Henrik Ullum som direktør for Statens Serum Institut, og siden har han skullet vænne sig til livet som embedsmand i mediernes spotlight. Det har været hårdt, men det hele værd, når han ind imellem politik, økonomi og jura stadig har tid til fagligt nørderi.
Det vrimler med anbefalinger, guidelines og retningslinjer i sundhedsvæsenet. Men faktisk er der meget ringe evidens for store dele af aktiviteten, fortæller tre overlæger, ligesom ressourcespildet vurderes til at være stort. Danske Regioner planlægger topmøde om forskning.
Siden direktør på Bornholms Hospital Annemarie Hellebek flyttede til solskinsøen for tre et halvt år siden, har hun brugt de lokale kulturtilbud som et redskab til at forstå bornholmerne og den historie, de er rundet af. Men hun ser også kultur som en nøgle til fællesskab.
A new study found that 18- to 24-year-olds who use cell phones while driving are more likely to engage in other risky driving behaviors associated with 'acting-without-thinking,' a form of impulsivity. These findings suggest the importance of developing new strategies to prevent risky driving in young adults, especially those with impulsive personalities.
As deadly as it is, cancer metastasis is a poorly understood process. A new study describes a cutting-edge tool for tracing the lineage and gene expression of thousands of individual metastatic cancer cells. Their findings open new angles for investigating the processes that drive metastasis.
Scientists summarize and critically appraise the current approaches to determining the concentrations of antimicrobials that increase AMR. By collating and assessing available data, they have recommended what these safe thresholds could be, to enable governments to act to reduce them.
Researchers have developed a new method which makes CRISPR gene editing more precise than conventional methods. The method selects the molecules best suited for helping the CRISPR-Cas9 protein with high-precision editing at the correct location in our DNA, the researchers explain.
The Uttarakhand region of India experienced a humanitarian tragedy on Feb. 7, 2021, when a wall of debris and water barreled down the Ronti Gad, Rishiganga and Dhauliganga river valleys. This debris flow destroyed two hydropower facilities and left more than 200 people dead or missing. A self-organized coalition of 53 scientists came together in the days following the disaster to investigate the c
Using a new 3D printing process, researchers have discovered how to tailor-make artificial body parts and other medical devices with built-in functionality that offers better shape and durability, while cutting the risk of bacterial infection at the same time.
Plant researchers have discovered an unusual and previously unknown reproductive strategy in plants: the Greek pipevine species 'Aristolochia microstoma' produces a unique mixture of volatiles that resembles the smell of dead and decaying insects to attract the pollinating fly genus 'Megaselia' (also known as 'coffin flies') to its trap-flowers.
The type of material present under glaciers has a big impact on how fast they slide towards the ocean. Scientists face a challenging task to acquire data of this under-ice landscape. Choosing the wrong equations for the under-ice landscape can have the same effect on the predicted contribution to sea-level rise as a warming of several degrees, according to researchers.
Hi everyone, I had recently ( maybe 20 days ago ) read this book and his ideas were really fascinating. He is asserting that the neocortex is composed of cortical columns which generate internal representation of outside world according to what sensory input they get. So each column generate its own model of the world. His whole idea is based on reference frames. He keeps going on explaining his
What is already established for inorganic semiconductors stays a challenge for their organic counterparts: Tuning the energy gap by blending different semiconducting molecules to optimize device performance. Now, scientists demonstrated how to reach this goal.
Researchers have found that nearly 20 percent of patients with unexplained sudden cardiac death — most of whom were under age 50 — carried rare genetic variants. These variants likely raised their risk of sudden cardiac death.
Soot particles from oil and wood heating systems as well as road traffic can pollute the air in Europe on a much larger scale than previously assumed. The evaluation of the sources during a measuring campaign in Germany showed that about half of the soot particles came from the surrounding area and the other half from long distances. This underlines the need to further reduce emissions of soot tha
Inaccessible workplaces, normative departmental cultures and 'ableist' academic systems have all contributed to the continued under-representation and exclusion of disabled researchers, according to an expert.
Through the biological fixation of the element nitrogen by the enzyme nitrogenase, organisms gain access to molecular nitrogen (N2) in the Earth's atmosphere, which is essential for building cellular structures. In addition, a vanadium-dependent variant of nitrogenase can reduce the toxic gas carbon monoxide (CO) to hydrocarbons. These reductions of N2 and CO are among the most important processes
Researchers have found that plants adapt to heat stress via a specific 'memory' mechanism. The JUMONJI family of proteins can control small heat shock genes, allowing plants to become heat tolerant for better adaptation to future heat stress. This research is applicable to a broad range of scientific fields and understanding this mechanism could contribute to maintaining the food supply under glob
Biomedical engineers have demonstrated that a class of interwoven composite materials called semi-interpenetrating polymer networks (sIPNs) can be produced by living cells. The approach could make these versatile materials more biologically compatible for biomedical applications such as time-delayed drug delivery systems.
Until now, systemic biomarkers to measure exercise effects on brain function and that link to relevant metabolic responses were lacking. A study shows a memory biomarker, myokine Cathepsin B (CTSB), increased in older adults following a 26-week structured aerobic exercise training. The positive association between CTSB and cognition, and the substantial modulation of lipid metabolites implicated i
Events of the past year have exposed the crisis of the digital divide in the U.S. To tackle this problem, researchers have developed a new tool to smooth the collection of federal broadband access data that helps pinpoint coverage gaps across the US.
Maritime litter is among the most urgent global pollution issues. Marine scientist have published an overview study of solutions for prevention, monitoring, and removal. They found that reducing ocean pollution requires more support, integration, and creative political decisiveness.
Children with reading and writing difficulties who are presented with text on screens with flickering white noise both read better and remember what they have read better, according to a Swedish-Norwegian study.
An exploratory investigation into the behavior of materials with desirable electric properties has resulted in the discovery of a structural phase of two-dimensional (2D) materials. The new family of materials are electrides, wherein electrons occupy a space usually reserved for atoms or ions instead of orbiting the nucleus of an atom or ion. The stable, low-energy, tunable materials could have po
Climate change exerts great pressure for change on species and biodiversity. A recent study conducted by the University of Helsinki and the Finnish Environment Institute indicates that the few moth and butterfly species (Lepidoptera) capable of adjusting to a changing climate by advancing their flight period and moving further north have fared the best in Finland. In contrast, roughly 40% of Lepid
Plants are constantly exposed to microbes: Pathogens that cause disease, commensals that cause no harm or benefit, and mutualists that promote plant growth or help fend off pathogens. For example, most land plants can form positive relationships with arbuscular mycorrhizal fungi to improve nutrient uptake. How plants fight off pathogens without also killing beneficial microbes or wasting energy on
People often think about human behavior in terms of what is happening in the present — reading a newspaper, driving a car, or catching a football. But other dimensions of behavior extend over weeks, months, and years.
Treating transplant patients with mild to moderate cases of COVID-19 with monoclonal antibodies is safe and helps prevent serious illness, according to a new study. These results are especially important because transplant patients who are infected with COVID-19 have a higher risk of severe illness and death.
Every year, landslides—the movement of rock, soil, and debris down a slope—cause thousands of deaths, billions of dollars in damages, and disruptions to roads and power lines. Because terrain, characteristics of the rocks and soil, weather, and climate all contribute to landslide activity, accurately pinpointing areas most at risk of these hazards at any given time can be a challenge. Early warnin
Researchers from Skoltech have designed and conducted experiments measuring gas permeability under various conditions for ice-containing sediments mimicking permafrost. Their results can be useful both in modeling and testing techniques for gas production from Arctic reservoirs and in tracing methane emission in high latitudes. The paper was published in the journal Energy & Fuels.
The addition of a simple processing step to saliva samples before testing may improve COVID-19 detection rate, eliminate the challenges of nasopharyngeal testing, and facilitate mass surveillance, researchers report.
Biological engineers have demonstrated a way to easily retrieve data files stored as DNA. This could be a step toward using DNA archives to store enormous quantities of photos, images, and other digital content.
Acoustic waves in gases, liquids, and solids usually travel at an almost constant speed of sound. Rotons are an exception: their speed of sound changes significantly with the wavelength, it is also possible that the waves travel backwards. Researchers are studying the possibilities of using rotons in artificial materials. These metamaterials might be used in the future to manipulate or direct soun
It is generally agreed that sperms 'swim' by beating or rotating their soft tails. However, a research team has discovered that ray sperms move by rotating both the tail and the head. The team further investigated the motion pattern and demonstrated it with a robot. Their study has expanded the knowledge on the microorganisms' motion and provided inspiration for robot engineering design.
Researchers report that Elovanoids, bioactive chemical messengers made from omega-3 very-long-chain polyunsaturated fatty acids, may block the virus that causes COVID-19 from entering cells and protect the air cells (alveoli) of the lung.
Most people listen to music throughout their day and often near bedtime to wind down. But can that actually cause your sleep to suffer? When sleep researcher Michael Scullin, Ph.D., associate professor of psychology and neuroscience at Baylor University, realized he was waking in the middle of the night with a song stuck in his head, he saw an opportunity to study how music — and particularly stu
Researchers at the University of Central Florida have published a first- of-its-kind study that shows that near-infrared (NIR) spectrum cameras can help python hunters more effectively track down these invasive snakes, especially at night.
Ketogenic metabolic therapy has been shown to successfully starve cancer cells of the glucose and glutamine they need to survive. In a new case study, a British man who rejected the standard of care to treat his glioblastoma has lived for more than 80 months with the typically fatal tumor after adopting a ketogenic diet, researchers report in the journal Frontiers in Nutrition
Inspired by people around the world who made music together while social distancing during the COVID-19 pandemic, researchers from Bar-Ilan University and the University of Chicago fused the latest advances in social neuroscience and the field of music to highlight five key functions and mechanisms of the brain that contribute to social connection through music. The findings illustrate that music
A new book highlights how Black women have historically used yoga to practice self-care. The pandemic has emphasized the importance of taking care of yourself amid anxiety, uncertainty, and stress. For Black women, who often face a disproportionate burden in society, self-care can also be a tool to counter the effects of systemic racism and trauma. Black Women's Yoga History: Memoirs of Inner Pea
www.iBiology.org Abrar Choudhury describes how he studied DNA methylation to understand the biology of meningioma and identify a novel candidate therapy. Meningioma is the most common intracranial tumor, with limited treatment options. In order to identify new therapies for meningioma, it is important to understand their underlying biology. In this Share Your Research talk, Dr. Abrar Choudhury de
Plants synthesize many diverse small molecules that affect function of the mammalian central nervous system, making them crucial sources of therapeutics for neurological disorders. A notable portion of neuroactive phytochemicals are lysine-derived alkaloids, but the mechanisms by which plants produce these compounds have remained largely unexplored. To better understand how…
Saliva samples are easier to collect than nasopharyngeal swabs for COVID-19 testing but can be mixed with mucus or blood, and some studies have found they produce less accurate results. A team of researchers has found that an innovative protocol that processes saliva samples with a bead mill homogenizer before real-time PCR (RT-PCR) testing results in higher sensitivity compared to NPS samples. Th
Researchers have developed an innovative way to use the clumped isotope method to reconstruct climate in the geological past on the seasonal scale. They show that dinosaurs had to deal with hotter summers than previously thought. The results suggest that in the mid latitudes, seasonal temperatures will likely rise along with climate warming, while seasonal difference is maintained. This results in
Race, age, income and health insurance status are factors in the distance patients must travel to reach the nearest certified stroke care, according to a nationwide analysis of US census data and road maps. The greatest distances were for those in rural areas and for American Indians.
The team looked in different regions of the brain, which are affected in Alzheimer's disease before looking for common changes across these cortical regions. They identified 220 sites in the genome, including 84 new genes, which showed different levels of DNA methylation in the cortex in individuals with more severe Alzheimer's disease, which weren't seen in the cerebellum.
The consumption of raw materials has increased notably in industry in general, and in the construction industry in particular, amidst growing concerns over sustainability issues. Concrete and mortar are the most commonly used materials in construction, and many studies are currently underway to try to reduce the harmful effects of their manufacture. Concrete and mortar are made by mixing water, sa
Many animals have evolved camouflage tactics for self-defense, but some butterflies and moths have taken it even further: They've developed transparent wings, making them almost invisible to predators. A team led by Marine Biological Laboratory (MBL) scientists studied the development of one such species, the glasswing butterfly, Greta oto, to see through the secrets of this natural stealth techno
Some four months ago, a devastating flood ravaged the Chamoli district in the Indian Himalayas, killing over 200 people. The flood was caused by a massive landslide, which also involved a glacier. Researchers at the University of Zurich, the WSL and ETH Zurich have now analyzed the causes, scope and impact of the disaster as part of an international collaboration.
Plastic bottles drifting in the sea; bags in the stomachs of turtles; COVID-19 masks dancing in the surf: Few images are as unpleasant to look at as those that show the contamination of our oceans. And few environmental issues are as urgent and as present in the public awareness. "Most people have an emotional connection to the sea. They think of ocean pollution as an attack on a place they long f
Emergent resistance to all clinical antibiotics calls for the next generation of therapeutics. Here we report an effective antimicrobial strategy targeting the bacterial hydrogen sulfide (H 2 S)–mediated defense system. We identified cystathionine -lyase (CSE) as the primary generator of H 2 S in two major human pathogens, Staphylococcus aureus and Pseudomonas aeruginosa , and discovered small mo
How eukaryotic cells assess and maintain sizes specific for their species and cell type remains unclear. We show that in the Arabidopsis shoot stem cell niche, cell size variability caused by asymmetric divisions is corrected by adjusting the growth period before DNA synthesis. KIP-related protein 4 (KRP4) inhibits progression to DNA synthesis and associates with mitotic chromosomes. The F BOX-LI
Coherent optical excitations in two-dimensional (2D) materials, 2D polaritons, can generate a plethora of optical phenomena that arise from the extraordinary dispersion relations that do not exist in regular materials. Probing of the dynamical phenomena of 2D polaritons requires simultaneous spatial and temporal imaging capabilities and could reveal unknown coherent optical phenomena in 2D materi
Ammonia (NH 3 ) is a globally important commodity for fertilizer production, but its synthesis by the Haber-Bosch process causes substantial emissions of carbon dioxide. Alternative, zero-carbon emission NH 3 synthesis methods being explored include the promising electrochemical lithium-mediated nitrogen reduction reaction, which has nonetheless required sacrificial sources of protons. In this st
Extending the framework of statistical physics to the nonequilibrium setting has led to the discovery of previously unidentified phases of matter, often catalyzed by periodic driving. However, preventing the runaway heating that is associated with driving a strongly interacting quantum system remains a challenge in the investigation of these newly discovered phases. In this work, we utilize a tra
We explored the bonding properties of the quantum corral (a circle of 48 iron atoms placed on a copper surface) reported by Crommie et al. in 1993, along with variants, as an artificial atom using an atomic force microscope (AFM). The original corral geometry confines 102 electrons to 28 discrete energy states, and we found that these states can form a bond to the front atom of the AFM with an en
Spiral galaxies have distinct internal structures, including a stellar bulge, a disk, and spiral arms. It is unknown when in cosmic history these structures formed. In this study, we analyzed observations of BRI 1335–0417, an intensely star-forming galaxy in the distant Universe, at a redshift of 4.41. The [C ] gas kinematics shows a steep velocity rise near the galaxy center and has a two-armed
Quiescent neural stem cells (NSCs) in the adult mouse ventricular-subventricular zone (V-SVZ) undergo activation to generate neurons and some glia. Here we show that platelet-derived growth factor receptor beta (PDGFRβ) is expressed by adult V-SVZ NSCs that generate olfactory bulb interneurons and glia. Selective deletion of PDGFRβ in adult V-SVZ NSCs leads to their release from quiescence, uncov
Predicting and understanding how people make decisions has been a long-standing goal in many fields, with quantitative models of human decision-making informing research in both the social sciences and engineering. We show how progress toward this goal can be accelerated by using large datasets to power machine-learning algorithms that are constrained to produce interpretable psychological theori
Hedgehog proteins govern crucial developmental steps in animals and drive certain human cancers. Before they can function as signaling molecules, Hedgehog precursor proteins must undergo amino-terminal palmitoylation by Hedgehog acyltransferase (HHAT). We present cryo–electron microscopy structures of human HHAT in complex with its palmitoyl–coenzyme A substrate and of a product complex with a pa
Viruses are ubiquitous pathogens of global impact. Prompted by the hypothesis that their earliest progenitors recruited host proteins for virion formation, we have used stringent laboratory evolution to convert a bacterial enzyme that lacks affinity for nucleic acids into an artificial nucleocapsid that efficiently packages and protects multiple copies of its own encoding messenger RNA. Revealing
In rodents, obesity and aging impair nicotinamide adenine dinucleotide (NAD + ) biosynthesis, which contributes to metabolic dysfunction. Nicotinamide mononucleotide (NMN) availability is a rate-limiting factor in mammalian NAD + biosynthesis. We conducted a 10-week, randomized, placebo-controlled, double-blind trial to evaluate the effect of NMN supplementation on metabolic function in postmenop
A decade after the first report, the family of two-dimensional (2D) carbides and nitrides (MXenes) includes structures with three, five, seven, or nine layers of atoms in an ordered or solid solution form. Dozens of MXene compositions have been produced, resulting in MXenes with mixed surface terminations. MXenes have shown useful and tunable electronic, optical, mechanical, and electrochemical p
Next-generation tissue-based biomarkers for immunotherapy will likely include the simultaneous analysis of multiple cell types and their spatial interactions, as well as distinct expression patterns of immunoregulatory molecules. Here, we introduce a comprehensive platform for multispectral imaging and mapping of multiple parameters in tumor tissue sections with high-fidelity single-cell resoluti
Ecological resilience is the magnitude of the largest perturbation from which a system can still recover to its original state. However, a transition into another state may often be invoked by a series of minor synergistic perturbations rather than a single big one. We show how resilience can be estimated in terms of average life expectancy, accounting for this natural regime of variability. We u
X-inactive specific transcript (Xist) RNA directs the process of X chromosome inactivation in mammals by spreading in cis along the chromosome from which it is transcribed and recruiting chromatin modifiers to silence gene transcription. To elucidate mechanisms of Xist RNA cis-confinement, we established a sequential dual-color labeling, super-resolution imaging approach to trace individual Xist
When students post on social media from off of school property, are those posts protected as free speech? The US Supreme Court will issue a ruling that decides that question before adjourning for the summer. When Brandi Levy, a junior varsity cheerleader at a Pennsylvania high school, learned that she didn't make the varsity cheerleading team, she did what any teenager might—she blew off some ste
In a breakthrough in metamaterials, for the first time in the world, researchers at Tel Aviv University have developed an innovative nanotechnology that transforms a transparent calcite nanoparticle into a sparkling gold-like particle. In other words, they turned the transparent particle into a particle that is visible despite its very small dimensions. According to the researchers the new materia
Present in blood, urine, and milk, the chemical compound urea is the primary form of nitrogen excretion in mammals. Testing for urea levels in dairy cows helps scientists and farmers understand how effectively nitrogen from feed is used in cows' bodies, with important economic implications for farmers in terms of feed costs, physiological effects for cows such as reproductive performance, and envi
On June 10, 2021, the European Space Agency (ESA) announced the selection of EnVision as its newest medium-class science mission. EnVision will make detailed observations of Venus to understand its history and especially understand the connections between the atmosphere and geologic processes. As a key partner in the mission, NASA provides the synthetic aperture radar, called VenSAR, to make high-
? Researchers from Tel Aviv University developed a new platform that can serve as a basis for innovative medications.? Applying processes of nanotechnology, the researchers were able to turn transparent calcite into artificial gold that can be used in thermotherapy for various types of cancer.
Medical education aspires to mitigate bias in future professionals by providing a robust curriculum that includes perspectives and practices for caring for sexual and gender minority (SGM) populations, including lesbian, gay, bisexual, transgender and intersex (LGBTQI) persons. To provide medical schools with a more systematic, uniform approach to teaching these topics in their curriculum, the Ass
Maritime litter is among the most urgent global pollution issues. Marine scientist Nikoleta Bellou and her team at Helmholtz-Zentrum Hereon have published an overview study of solutions for prevention, monitoring, and removal in the renowned scientifically journal Nature Sustainability. They found that reducing ocean pollution requires more support, integration, and creative political decisiveness
Replacing just one of concrete's main ingredients with volcanic rock could slash carbon emissions from manufacturing the material by nearly two-thirds, according to a new study. Concrete has given us the Pantheon in Rome, the Sydney Opera House, the Hoover Dam, and countless blocky monoliths. The artificial rock blankets our cities and roadways, underlies wind farms and solar panel arrays—and wil
AMP has published consensus recommendations to aid in the design and validation of clinical CYP2D6 assays, promote standardization of testing across different laboratories and improve patient care. The manuscript, "Recommendations for Clinical CYP2D6 Genotyping Allele Selection: A Joint Consensus Recommendation of the Association for Molecular Pathology, College of American Pathologists, Dutch Pha
AP-HP Greater Paris University Hospitals and Owkin announced the recent results of their ongoing strategic collaboration at ASCO 2021. Their abstract demonstrates the first AI-based tool for predicting genomic subtypes of pancreatic cancer (PDAC) developed from machine learning applied to histology slides. The tool, a trained and validated AI model, is usable in clinical practice worldwide and ope
Evidence suggests auditory and vestibular effects should be added to the growing list of physiological impacts of COVID-19. During the 180th Meeting, Colleen Le Prell from the University of Texas at Dallas will talk about hearing and balance disorders associated with coronavirus infection and how pandemic-related stress and anxiety may aggravate tinnitus symptoms. Her presentation, "Hearing disord
Elever med sämre socioekonomiska förutsättningar får sämre möjligheter att lära sig matematik. Undervisningen täcker in färre delar av kunskapsinnehållet – och fler lärare uppger att de inte är väl förberedda när de ska undervisa. Det visar en avhandling i pedagogik vid Göteborgs universitet har jämfört, vars författare efterlyser åtgärder för att skapa en mer likvärdig skola. – Det är en ojämlik
A Ludwig Cancer Research study adds to growing evidence that immune cells known as macrophages inhabiting the body cavities that house our vital organs can aid tumor growth by distracting the immune system's cancer-killing CD8+ T cells.
Researchers at Michigan Medicine found people with cerebral palsy have fragile bones that present high fracture risk, but at different times across the lifespan compared to the general population. The results helped them develop new sex-specific critical periods of bone health for this population.
Endangered blue whales are present and singing off the southwest coast of India, research shows. The findings suggest conservation measures should include this region, which is considering expanding tourism. Analysis of recordings from late 2018 to early 2020 in Lakshadweep, an archipelago of 36 low-lying islands west of the Indian state of Kerala, detected whales with a peak activity in April an
Highly dispersed platinum catalysts provide new possibilities for industrial processes, such as the flameless combustion of methane, propane, or carbon monoxide, which has fewer emissions and is more resource efficient and consistent than conventional combustion. In the journal Angewandte Chemie, a team of researchers reports on which platinum species are active in high-temperature oxidations and
Actively restoring oyster reefs—beyond simply protecting them from harvest—can create big payoffs for habitat quality and the other species that flock to them. A new study from the Smithsonian Environmental Research Center (SERC), published June 3 in the journal Marine Ecology Progress Series, compared restored, protected and harvested areas using photos and video footage from roughly 200 sites.
Joining a club that sparks a new interest, playing a new intramural sport or finding a new group of friends may be just as indicative of a college freshman's loss of self-control as drinking or drug use, according to new research at West Virginia University.
This study will benefit scientists and experts in brain research where new discoveries of biomarkers are needed to form part of routine clinical practice protocols. The study relies on zebrafish Parkinson's Disease model, showing how cytosolic dsDNA of mitochondrial origin can accumulate in brains cells thereby contributing to PD pathogenesis. The evidence presented in this manuscript illustrates
The Pfizer COVID-19 vaccine is protective against several SARS-CoV-2 variants that have emerged, according to new research presented this week in the journal mBio, an open-access journal of the American Society for Microbiology. While this is good news, the study also found that the only approved monoclonal antibody therapy for SARS-CoV-2 might be less effective against SARS-CoV-2 variants in labo
Black people have a higher risk of colorectal cancer than white people, but this risk is likely not due to genetics. Data from a recent study by researchers from the US Department of Veterans Affairs, Regenstrief Institute and Indiana University School of Medicine adds more data to the existing evidence.
Highly dispersed platinum catalysts provide new possibilities for industrial processes, such as the flameless combustion of methane, propane, or carbon monoxide, which has fewer emissions and is more resource efficient and consistent than conventional combustion. In the journal Angewandte Chemie, a team of researchers reports on which platinum species are active in high-temperature oxidations and
The scientific world has been delving ever deeper into cancer, scourging for even the tiniest biomolecule that could amp up the cure for the deadly disease. A recent discovery in this regard is the gene LIM domain only 1, whose coded protein has a role in tumor formation. In a new article in Chinese Medical Journal, researchers have reviewed studies detailing molecular features of this gene for po
Contributor is a science writer and a final-year Ph.D. student in molecular engineering at the University of Chicago. Outside the lab, she freelances for various publications, including National Geographic, Scientific American, Science News, Slate and others. Follow her at @ goes_by_kim . Author social media Twitter
The world's first wooden satellite is on the way, in the shape of the Finnish WISA Woodsat. ESA materials experts are contributing a suite of experimental sensors to the mission as well as helping with pre-flight testing.
Want your brain to function at maximum capacity every day? Well, there are two ways you can do it. The first is to exercise for at least an hour every day, eat a perfectly balanced diet of low-fat sugar-free foods packed with essential vitamins and minerals, get eight hours of high quality sleep every night, and practice mindfulness and meditation to reduce stress and anxiety. Do all those things
Research conducted at LSU Health New Orleans Neuroscience Center of Excellence reports that Elovanoids, bioactive chemical messengers made from omega-3 very-long-chain polyunsaturated fatty acids discovered by the Bazan lab in 2017, may block the virus that causes COVID-19 from entering cells and protect the air cells (alveoli) of the lung.
There are about 1,400 known human pathogens—viruses, bacteria, fungi, protozoa and helminths that can cause a person's injury or death. But in a world with a trillion individual species of microorganisms, where scientists have counted only one one-thousandth of one percent, how likely is it researchers have discovered and characterized everything that might threaten people?
Smoking, high blood pressure, diabetes, and other risk factors for cardiovascular diseases also increase the likelihood of suffering from depressive mood or depression. Until now, however, it was unclear whether this influence changes over the course of life or is independent of age. A study by the Max Planck Institute for Human Cognitive and Brain Sciences shows: Among those over 65, these risk f
Global ecosystem restoration efforts are often measured by billions of trees planted or square kilometers of land restored. But there is a critical void in the agenda: the social and political dimensions that make restoration a success.
As more people are taking advantage of music on the go, personal audio systems are pumping up the volume to the detriment of the listener's hearing. During the 180th ASA Meeting, Daniel Fink from The Quiet Coalition and Jan Mayes will talk about current research into personal audio system usage and the need for public health hearing conservation policies. Their session, "Personal audio system use
Women are just as inclined as men to vote against a policy to reduce a gender pay gap if they are personally benefiting from the status quo. This is one of the main findings of my new study, which was published in January 2021 in the journal Applied Economics Letters.
Exposure to particulate matter (PM) has been associated with adverse health effects. A large fraction of these particles consists of volatile or semi-volatile materials, such as emissions generated from cooking, automobiles and tobacco products. The dynamics of the evaporation process of such volatile particles has been an active area of research since the 19th century. However, existing measureme
As part of ESA's commitment to develop and build satellite missions that push the boundaries of satellite technology and Earth science, four new mission ideas—Cairt, Nitrosat, Seastar and Wivern—have been selected to enter pre-feasibility study and compete to be the eleventh Earth Explorer mission.
Wageningen University & Research scientists have demonstrated that genes influence swimming fitness of tilapia. As there are indications that fitter fish are also healthier and more resilient, the researchers recommend including fitness in selective breeding programs for farmed fish. Nile tilapia is the second most cultivated fish species in the world after carp and provide cheap protein and essen
As the G7 summit gets underway, all the group's members are now firmly committed to achieving net zero by 2050. This is quite a turnaround from just two years ago when the UK became the first major economy to make such a pledge. At the time of writing 121 countries are signed up to the UNFCCC's Climate Ambition Coalition and 35 of the 38 members of the OECD (to name and shame the laggards, they ar
Microscopic organisms known as extremophiles inhabit some of the last places on Earth you might expect to find life, from the extreme pressures of the ocean floor to freezing ice caps. Understanding how these microbes survive by interacting with different metals and gases is opening up new knowledge about Earth's elements and their potential uses.
A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body's own immune system can eliminate cancer cells without damaging host cells. The findings have the potential to develop first-in-class medicines that are designed to be selective for cancer cells and non-toxic to normal cells and tissues.
A combination of ibrutinib and venetoclax was found to provide lasting disease remission in patients with newly diagnosed chronic lymphocytic leukemia (CLL), according to researchers at The University of Texas MD Anderson Cancer Center. Findings from the single-institution Phase II study were published today in JAMA Oncology and provide the longest follow-up data on patients treated with this drug
The team studied blood samples from children from two ethnic groups in remote rural areas of Burkina Faso, Gouin and Fulani, to see how they responded to the malaria parasite Plasmodium falciparum. The team discovered an elevation of immune-dampening steroid molecules and a strong immunosuppressive signature in Gouin children. Studying the enigmatic less malaria-susceptible Fulani ethnic group rev
A new device that fits over a person's ears and enables non-invasive measurement of real-time changes in blood alcohol levels through the skin is presented in a proof-of-principle study in Scientific Reports.
Earlier this year, the US National Institutes of Health (NIH) acknowledged the impact of structural racism on biomedical science and committed to doing more to dismantle it. Now, in a commentary appearing June 10 in the journal Cell, NIH Director Francis Collins and colleagues describe the NIH's UNITE initiative and how it differs from the agency's previous diversity, equity, and inclusion efforts
An RUDN and Shahid Beheshti University(SBU) chemist proposed an eco-friendly method for the synthesis of pyrrole and pyrazole derivatives with a wide range of applications in medicine: from antidepressants to anticancer. Moreover, the synthesized compounds possess interesting fluorescence features, and the bioactive scaffolds might attract great interest in the fields of clinical diagnostics and b
The fact that photosynthesis uses sunlight and atmospheric carbon dioxide to produce sugars has been known for more than a century. But how photosynthesis manages to maintain sugar production through variations in the availability of sunlight and carbon dioxide has remained a mystery until now.
How much do the effects of climate change contribute to extreme weather events? It's hard to say—the variables involved are plentiful, each event is unique, and we can only do so much to investigate what didn't happen. But a new paper from Lawrence Berkeley National Laboratory (Berkeley Lab) climate scientist Michael Wehner investigates the question for one particular element of one significant st
Cell viability requires that a variety of functions at the cell membrane are maintained properly. P-type ATPases translocate substrates across the membrane, and they have evolved into different types taking care of specific substrates within a diverse range. Now, key structural aspects have been described on how two different types of P-type ATPases—a Ca2+ transporting Ca2+ -ATPase and a lipid tra
A CABI-led study has revealed that the success of Classical Biological Control (CBC) in Europe, North Africa and the Middle East is only rarely dependent on the released biological control agent, but more often on other factors, such as the target pest, its host plant, or the circumstances of the releases.
Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have described a potential disease-causing mechanism in hypertrophic cardiomyopathy (HCM), the most frequent hereditary disease of the heart. The study, published in the journal ACS Nano, provides the first description of an association between this disease and mechanical alterations to a component of the contractile mach
Generally, physics and financial systems are not easily associated in people's minds. Yet, principles and techniques originating from physics can be very effective in describing the processes taking place on financial markets. Modeling financial systems as networks can greatly enhance our understanding of phenomena that are relevant not only to researchers in economics and other disciplines, but a
Researchers from Tel Aviv University took part in a new international study proposing an amendment to the widely accepted theory on the extinction of animal species—by moving the focus from the animal's body size to its reproductive capacity. The researchers found gaps and incompatibilities between mammals and amphibians in the relation between body size and extinction risk: Whereas large mammals