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BAKTERIER KAN MANIPULERES TIL AT BEHANDLE SYGDOMME. With the use of bio-hacking a way of rewiring two-component system input sensors of bacteria, scientists can manipulate the output result. This new technique could be used for modifying gut bacteria to treat diseases and could be used as industrial or environmental sensors.
 
MINI-HJERTER KAN NU DYRKES I LABORATORIET. Organs such as liver or lungs have been grown in labs for some time, but for the first time this has successfully been done for a miniature beating heart organoid. This allows scientists to explore how babie's hearts can fully repair themselves compared to adult hearts. 
 
IMMUNSYSTEMETS T-CELLER KAN MANIPULERES TIL AT VIRKE BEDRE. By editing the genome of the T cells, scientists were able to make them stronger, allowing patient's own immune system to combat cancer cells. This could be used in a combination with other already existing cancer treatments or just by itself. 

Researchers see atoms at record resolution

In 2018, Cornell researchers built a high-powered detector that, in combination with an algorithm-driven process called ptychography, set a world record by tripling the resolution of a state-of-the-art electron microscope.

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Vaccine Lottery Tickets Are Sad, but Also Perfect

Every American state has laws requiring vaccination . If you want your children to attend kindergarten, you must vaccinate them against rubella. Most parents comply because they don't want anyone going deaf from congenital rubella. And if that isn't convincing enough, then there is the ominous threat of having to homeschool. But these laws have holes , and more people are going through them. In t

11min

Researchers create world's most power-efficient high-speed ADC microchip

Researchers at Brigham Young University have built a new analog-to-digital converter (ADC) — a tiny piece of technology present in almost every electronic piece of equipment that converts analog signals (like a radio wave) to a digital signal — with record-breaking power efficiency. The ADC consumes only 21 milli-Watts of power at 10GHz for ultra-wideband wireless communications.

13min

Albert Einstein letter with E=mc2 equation in his own hand sells for $1.2m

Only two similar examples of world-changing equation known 1946 letter to physicist Ludwik Silberstein auctioned Related: Albert Einstein's 'God letter' reflecting on religion auctioned for $3m A handwritten letter by Albert Einstein that contains his famous E=mc 2 equation has sold at auction for more than $1.2m, about three times more than it was expected to get, a Boston-based auction house sa

14min

'Dingoes were here first': the landowners who say letting 'wild dogs' live pays dividends

Some farmers see a vicious pest that should be shot on sight, others a native species that plays a vital role in Australia's ecosystem Read more of our Modern Outback series here Sign up for email notifications from our Modern Outback series By their own admission, John Knight and Caroline Thomas are blow-ins to the cattle country in South Australia's far north. An Adelaide cardiac surgeon and a

14min

Senator "Can't Imagine" UFOs Came From Anywhere on Earth

Otherworldly Tech New Mexico Senator Martin Heinrich recently joined the ranks of prominent public officials suggesting that there may actually be something otherworldly about all of the UFO and unexplained aerial phenomena (UAP) footage and reports being scrutinized by military and intelligence leaders. "I don't know what it is, but any time you have legitimate pilots describing something that d

26min

NASA's New Mars Rover Is Preparing to Gather Samples That May Reveal Ancient Life

About Time Perseverance, NASA's latest Mars rover, is gearing up to finally begin its long-awaited mission : gathering samples of Mars rocks and packaging them for a return journey to Earth, where they'll be tested for signs of ancient microbial life, according to a video update tweeted from the Mars rover's anthropomorphized Twitter account. "I'm preparing to collect Martian samples in the searc

40min

Nanofiber filter captures almost 100 percent of coronavirus aerosols in experiment

A filter made from polymer nanothreads blew three kinds of commercial masks out of the water by capturing 99.9 percent of coronavirus aerosols in an experiment. The study compared the effectiveness of surgical and cotton masks, a neck gaiter, and electrospun nanofiber membranes. The cotton mask and neck gaiter only removed about 45 percent to 73 percent of the aerosols. The surgical mask did much

1h

The Cancellation of Nikole Hannah-Jones

Earlier this week Nikole Hannah-Jones, the New York Times writer in charge of the 1619 Project, was denied a tenured professorship at the University of North Carolina's journalism school. The faculty recommended her for a job, and a committee headed by a UNC trustee expressed doubts about her suitability. Other trustees reportedly said they would not approve her for tenure. The faculty countered

1h

World's Largest Iceberg Breaks off Antarctica

Iceberg Ahead A gigantic iceberg, roughly 70 times the size of Manhattan, has broken off from the Antarctic, in the process becoming the world's largest iceberg, according to The European Space Agency (ESA). The gigantic slab of ice, 1,668 square miles in size, is now floating in the Weddell Sea south east of South America, and was spotted by the ESA's Copernicus Sentinel-1, a land and sea monito

1h

The Mirror Home Gym Lets You Say Goodbye to Health Clubs Once and for All

If you were forced to switch to an at-home workout in 2020, you're not alone. In fact, even prior to the pandemic, many people were choosing to build the perfect at-home gym so they could conveniently exercise around their busy schedules. However, since the start of the pandemic, 60-percent of Americans found they enjoyed working out at home so much, they have no plans to return to the gym… ever

1h

Optical computation of a spin glass dynamics with tunable complexity [Applied Physical Sciences]

Spin glasses (SGs) are paradigmatic models for physical, computer science, biological, and social systems. The problem of studying the dynamics for SG models is nondetermistic polynomial-time (NP) hard; that is, no algorithm solves it in polynomial time. Here we implement the optical simulation of an SG, exploiting the N segments…

1h

Nanoparticle-enabled innate immune stimulation activates endogenous tumor-infiltrating T cells with broad antigen specificities [Immunology and Inflammation]

Tumors are often infiltrated by T lymphocytes recognizing either self- or mutated antigens but are generally inactive, although they often show signs of prior clonal expansion. Hypothesizing that this may be due to peripheral tolerance, we formulated nanoparticles containing innate immune stimulants that we found were sufficient to activate self-specific…

1h

Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer [Medical Sciences]

Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with limited treatment options. Although activating mutations of the KRAS GTPase are the predominant dependency present in >90% of PDAC patients, targeting KRAS mutants directly has been challenging in PDAC. Similarly, strategies targeting known KRAS downstream effectors have had limited clinical success…

1h

Dynamic population stage structure due to ȷuvenile-adult asymmetry stabilizes complex ecological communities [Ecology]

Natural ecological communities are diverse, complex, and often surprisingly stable, but the mechanisms underlying their stability remain a theoretical enigma. Interactions such as competition and predation presumably structure communities, yet theory predicts that complex communities are stable only when species growth rates are mostly limited by intraspecific self-regulation rather than…

1h

Random heterogeneity outperforms design in network synchronization [Applied Physical Sciences]

A widely held assumption on network dynamics is that similar components are more likely to exhibit similar behavior than dissimilar ones and that generic differences among them are necessarily detrimental to synchronization. Here, we show that this assumption does not generally hold in oscillator networks when communication delays are present….

1h

Elementary mechanisms of calmodulin regulation of NaV1.5 producing divergent arrhythmogenic phenotypes [Physiology]

In cardiomyocytes, NaV1.5 channels mediate initiation and fast propagation of action potentials. The Ca2+-binding protein calmodulin (CaM) serves as a de facto subunit of NaV1.5. Genetic studies and atomic structures suggest that this interaction is pathophysiologically critical, as human mutations within the NaV1.5 carboxy-terminus that disrupt CaM binding are linked…

1h

Structure of Ycf1p reveals the transmembrane domain TMD0 and the regulatory region of ABCC transporters [Biochemistry]

ATP binding cassette (ABC) proteins typically function in active transport of solutes across membranes. The ABC core structure is composed of two transmembrane domains (TMD1 and TMD2) and two cytosolic nucleotide binding domains (NBD1 and NBD2). Some members of the C-subfamily of ABC (ABCC) proteins, including human multidrug resistance proteins…

1h

Hydrodynamic shear dissipation and transmission in lipid bilayers [Biophysics and Computational Biology]

Vital biological processes, such as trafficking, sensing, and motility, are facilitated by cellular lipid membranes, which interact mechanically with surrounding fluids. Such lipid membranes are only a few nanometers thick and composed of a liquid crystalline structure known as the lipid bilayer. Here, we introduce an active, noncontact, two-point microrheology…

1h

Flexoelectricity in soft elastomers and the molecular mechanisms underpinning the design and emergence of giant flexoelectricity [Applied Physical Sciences]

Soft robotics requires materials that are capable of large deformation and amenable to actuation with external stimuli such as electric fields. Energy harvesting, biomedical devices, flexible electronics, and sensors are some other applications enabled by electroactive soft materials. The phenomenon of flexoelectricity is an enticing alternative that refers to the…

1h

The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-I [Microbiology]

COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic and has claimed over 2 million lives worldwide. Although the genetic sequences of SARS-CoV and SARS-CoV-2 have high homology, the clinical and pathological characteristics of COVID-19 differ significantly from those of SARS. How and whether…

1h

Entire genome from Pestera Muierii 1 sequenced

Researchers have successfully sequenced the entire genome from the skull of Pestera Muierii 1, a woman who lived in today's Romania 35,000 years ago. Her high genetic diversity shows that the out of Africa migration was not the great bottleneck in human development but rather this occurred during and after the most recent Ice Age.

1h

Passenger Jets May Get Blasted by Dangerous Radiation, Scientists Warn

It turns out that traveling in a passenger airplane could expose you to dangerous levels of cosmic radiation — under specific circumstances. A team of scientists from the University of Toulouse modeled existing flight plans and found that they would be exposed to the cosmic rays given off by particularly severe radiation storms, according to a research summary in Eos . The research shows that, gi

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