Immunisation panel says there is 'substantial uncertainty about the benefit' of the vaccine given risk of rare type of blood clot See all our coronavirus coverage Canada on Monday suspended the use of the Oxford/AstraZeneca coronavirus vaccine for people under 55 following concerns it might be linked to rare blood clots. The pause was recommended by the National Advisory Committee on Immunization
A new experimental treatment could someday give people a way to grow missing teeth , if early research on lab animals holds up. Scientists at Japan's Kyoto University and the University of Fukui developed a monoclonal antibody treatment that seems to trigger the body to grow new teeth, according to research published last month in the journal Science Advances . If upcoming experiments continue to
Major League Baseball is scheduled to hold its 91st All-Star Game at Truist Park in Atlanta on July 13—the first time in 21 years the league's annual showcase is to be played in that city. But pro baseball should extend Atlanta's All-Star drought, and other sports should avoid scheduling their own signature events in Georgia, to show Republican state lawmakers that their latest efforts at voter s
Most people know mother-of-pearl, an iridescent biomineral also called nacre, from buttons, jewelry, instrument inlays and other decorative flourishes. Scientists, too, have admired and marveled at nacre for decades, not only for its beauty and optical properties but because of its exceptional toughness.
The AstraZeneca COVID-19 vaccine is indispensable right now. As one of the first vaccines out of the gate, it's been at the center of the World Health Organization's plan to roll out some 2 billion doses to 92 nations by the end of the year. It's also one of just a handful of vaccines that are already being produced and distributed on such a massive scale that they might change the near-term cour
An interdisciplinary team at Monash University discovered a new universal rule of biological growth that explains surprising similarities in the shapes of sharp structures across the tree of life, including teeth, horns, claws, beaks, animal shells, and even the thorns and prickles of plants.
When humans look out at a visual landscape like a sunset or a beautiful overlook, we experience something—we have a conscious awareness of what that scene looks like. This awareness of the visual world around us is central to our everyday existence, but are humans the only species that experiences the world consciously? Or do other non-human animals have the same sort of conscious experience we do
We are not venomous, and neither are mice—but within our genomes lurks that potential, suggest scientists from the Okinawa Institute of Science and Technology Graduate University (OIST) and the Australian National University. Reporting this week in PNAS, the researchers found that the genetic foundation required for oral venom to evolve is present in both reptiles and mammals.
Earth has experienced five major mass extinction events over the past 500 million years. Massive volcanic eruptions have been identified as the major driver of the environmental changes that precipitated at least three of these extinction events. The fifth and most recent event—the end-Cretaceous mass extinction—occurred 66 million years ago and was responsible for wiping out dinosaurs. Researcher
A team of researchers from Universidade de São Paulo, Universidade Federal do Rio Grande do Sul and Universitat Pompeu Fabra, has found evidence of a genetic Australasian influence in more parts of South America than just the Amazon. In their paper published in Proceedings of the National Academy of Sciences, the group describes their study of a genomic dataset from multiple South American populat
Within the realm of quantum mechanics, the generation of quantum entanglement remains one of the most challenging goals. Entanglement, simply put, is when the quantum state of each particle or a group of particles is not independent of the quantum states of other particles or groups, even over long distances. Entangled particles have always fascinated physicists, as measuring one entangled particl
Oral venom systems evolved multiple times in numerous vertebrates enabling the exploitation of unique predatory niches. Yet how and when they evolved remains poorly understood. Up to now, most research on venom evolution has focused strictly on the toxins. However, using toxins present in modern day animals to trace the…
Different models have been proposed to elucidate the origins of the founding populations of America, along with the number of migratory waves and routes used by these first explorers. Settlements, both along the Pacific coast and on land, have been evidenced in genetic and archeological studies. However, the number of…
A 2 to 4 °C warming episode, known as the Latest Maastrichtian warming event (LMWE), preceded the Cretaceous–Paleogene boundary (KPB) mass extinction at 66.05 ± 0.08 Ma and has been linked with the onset of voluminous Deccan Traps volcanism. Here, we use direct measurements of melt-inclusion CO2 concentrations and trace-element…
Nature Communications, Published online: 30 March 2021; doi:10.1038/s41467-021-22097-0 Nutritional modification including fasting has been shown to reduce cardiometabolic risk linked to western diet. Here the authors show implementation of fasting resulted in alterations to the intestinal microbiota, and circulating immune cells, improving blood pressure and body weight in patients with metabolic
According to experts at analyst firm Jefferies, Bloomberg reports , smokers may soon be poised to disappear from many markets. "With regulators and tobacco ambitions increasingly aligned, in many countries, no smokers within a generation could become a reality," analyst Owen Bennett wrote in a recent statement. "If smoke-free is to happen, this is only achieved with the support of [reduced-risk p
Last August, Pape and his family went on a city break to Birmingham, making the most of chancellor Rishi Sunak's discount scheme. The day after he arrived home, his symptoms began Amanda Pape didn't want to go on a city break to Birmingham during a pandemic, but her husband, Bob, a 53-year-old lawyer, insisted. "Bob was convinced that the government would not allow people to travel if it wasn't s
5G Power A team of researchers from Georgia Tech has created a 3D printed antenna that can harvest electromagnetic energy from 5G signals and use it as a power source. The researchers claim the technology could one day turn 5G networks into "a wireless power grid" for small internet-connected devices and sensors — a fascinating alternative, or augmentation, for battery-powered gadgets. The main d
Despite the ongoing, accelerating vaccine rollout, the number of new daily coronavirus cases in the United States is once again starting to creep upward. And that has CDC Director Dr. Rochelle Walensky scared, she told reporters during a Monday morning briefing. "I'm gonna pause here, I'm gonna lose the script, and I'm gonna reflect on the recurring feeling I have of impending doom," Walensky sai
SpaceX launched its latest full-scale Starship prototype to a height of ten kilometers this morning — but we couldn't see very much this time around. This time, we only heard the explosion that rocked the launch site. The sky lit up in orange hues, suggesting at what we could've seen if it wasn't for the heavy fog blanketing the the space company's Boca Chica, Texas, launch site. It's another wor
The marine biologist Jay Barlow likes to say that he went looking for the last of the Ice Age mastodons and instead bumped into a unicorn. It's a land-based metaphor to help us, a landlubbing species, make sense of what he witnessed late last year, though in fact the mystery unfolded entirely out of sight of land. In 2014, a team of scientists described acoustic recordings taken far off the coast
Spasms, memory loss and hallucinations among symptoms of 43 patients in Acadian region of New Brunswick province Doctors in Canada are concerned they could be dealing with a previously unknown brain disease amid a string of cases involving memory loss, hallucinations and muscle atrophy. Politicians in the province of New Brunswick have demanded answers, but with so few cases, experts say there ar
Stanford University scientists determine sequences of Pfizer and Moderna vaccines from vials set to be discarded Scientists have determined the "recipes" for two Covid-19 vaccines using leftovers in vials bound for the trash and published the mRNA sequences on Github, the online repository for software code. The group of scientists from Stanford University were able to determine the sequences of
The UK's woods are full of strange specimens. But they aren't easy to identify – even for the experts Why is it hard to get our head around fungi? – podcast A host of otherworldly characters are squatting in the wood. Conventional toadstools make way for more gelatinous bodies slopping around fallen trees, dead wood and tree stumps during the coldest months of the year. Many are wood-decaying fun
T o hear Democratic leaders decry gerrymandering as part of their current bid to enact landmark voting-rights legislation, you'd think the centuries-old practice was a mortal threat to the republic. But political necessity could soon demand that Democrats drop their purity act. To keep their narrow House majority, they might have to deploy the tactic everywhere they can, and every bit as aggressi
Another day, another Starship prototype explosion. In November, SpaceX's SN8 met its early damage after smashing into the ground, followed by SN9 in February. SN10 came closest to touching down successfully earlier this month, appearing to make a soft landing before blowing to bits mere minutes later. Less than a month later, SpaceX rolled out its SN11 prototype onto the launchpad. This morning's
Did Covid-19 come from animal markets? It's unclear. Did it emerge from a lab? Also unclear. Here's what a new W.H.O. report says — including questions that the agency's own chief raised about the findings.
Voltswagen German carmaker Volkswagen is really rebranding its North American division to "Voltswagen," a nod to its electrified future. The company accidentally leaked the news, as spotted by CNBC , on Monday afternoon, with many suggesting it may have been a poorly timed April fool's joke. Now, VW has confirmed that is indeed renaming the division in a press release . "We might be changing out
I've always been a rule follower. So when I learned that my state, Virginia, was currently vaccinating only people older than 65, people with health conditions, and essential workers, I decided to patiently wait my turn. I didn't prowl around pharmacies and hospitals at closing time, hoping for an extra dose. A few weeks ago, I signed up for Virginia's COVID-vaccine waitlist, closed my laptop, an
Take a look at the numbers 294,001, 505,447 and 584,141. Notice anything special about them? You may recognize that they're all prime — evenly divisible only by themselves and 1 — but these particular primes are even more unusual. If you pick any single digit in any of those numbers and change it, the new number is composite, and hence no longer prime. Change the 1 in 294,001 to a 7, for instance
Despite some claims on cable news that President Joe Biden was " caught off guard " or " completely unprepared ," his administration foresaw the growing number of unaccompanied child migrants at the southwestern border. I worked in Barack Obama's White House during a similar surge in 2014. After the November election, I served on the Biden transition team, helping prepare the new administration f
A major component of NASA's Psyche spacecraft has been delivered to the agency's Jet Propulsion Laboratory in Southern California, where the phase known as assembly, test, and launch operations is now underway. Over the next year, the spacecraft will finish assembly and undergo rigorous checkout and testing before it's shipped to Cape Canaveral, Florida, for an August 2022 launch to the main aster
American political discourse was not exactly harmonious five years ago, but over the course of Donald Trump's presidency, it corroded even further. What's called the national conversation is really just millions of people communicating with each other, and if you could tune out all the yelling, you might be able to detect some of the silences that have arisen when two people stopped talking entir
The extinct human lineage nicknamed "the hobbit" may not be a distant relative of modern humans as previously thought. Instead, hobbits may be members of the mysterious close relatives of modern humans known as Denisovans.
W hy did so many Republicans— 147 of them —object to the Electoral College result on January 6? Most voted to overturn the election out of fear. Not fear of the angry mob that had invaded the Capitol hours earlier, but fear of the voters who might threaten their reelection––specifically in their next party primary. This is the "primary problem" in the U.S. political system today: A small minority
The idea of the atom goes as far back as the ancient Greek philosopher Democritus in about 400 B.C.E. This led to his "theory of eidôla " to explain how our minds create the illusion of reality. Democritus was one of the first determinists, arguing that a world made only of atoms and controlled by the laws of physics left no room for free will. Philosophers love "The Matrix". It's the perfect int
Secret Code On Monday, the US Strategic Command — that's the agency that controls the military's nukes — tweeted a bizarre string of characters that left the internet confused and perhaps mildly concerned. Not that there's anything wrong with occasionally firing up Twitter and broadcasting ";l;;gmlxzssaw" to the world, of course. But Stratcom helps oversee and manage the country's nuclear arsenal
Like many countries, China has a health care problem. Changing demographics and lifestyles mean demand for health care is outstripping growth in medical resources and its cost is rising faster than the insurance premium. With 250 million people over the age of 60, the world's most populous country is ageing. Diseases associated with more affluent societies, such as cardiovascular conditions and d
An international team of astronomers has carried out a comprehensive radio and X-ray monitoring of a black hole X-ray binary known as MAXI J1348–630. The observational campaign provided important insights into the evolution of the source's compact and transient jets. The study was presented in a paper published March 22 on arXiv.org.
A team of scientists from Heriot-Watt University has created an underwater observatory in the Faroe-Shetland Channel—and found its waters are teeming with oil-eating bacteria that could help deal with future oil spills.
The promising field of spintronics seeks to manipulate electron spin to make a new breed of small and low-power electronic devices. A recent study used Argonne's Advanced Photon Source to bring the widespread use of spintronics closer to reality.
In preparation for cell division, cells need to replicate the DNA that they contain. A team of researchers from TU Delft, collaborating with investigators from the Francis Crick Institute in London, has now shown that the protein building blocks involved in the initial steps of DNA replication are mobile but reduce their speed at specific DNA sequences on the genome. Their findings, which were pub
The news: A "real-world" study of 3,950 people in six states found that two doses of the Pfizer-BioNTech and Moderna vaccines cut the risk of infection by 90%. The findings are broadly in line with the 95% and 94% efficacy that the Pfizer and Moderna vaccines showed, respectively, in their clinical trials. The details: The US Centers for Disease Control and Prevention study recruited essential wo
Two separate clusters of UK variant spread in Brisbane when unvaccinated health workers contracted coronavirus The Queensland hospital system was already "stressed" before the latest Covid outbreak partly because everyone with the virus is moved from hotel quarantine into hospital, but not all hospital workers have been vaccinated yet, experts say. There are now two separate clusters of the infec
Our colleagues from The age of extinction , Phoebe Weston and Patrick Greenfield, are back with two new episodes. We often talk as if we know what species exist in the world – but we don't. Could misclassifying the notoriously cryptic fungi have broader implications for what we know about the environment, and how we care for it? Continue reading…
Prolonged and potentially destabilizing water shortages will become commonplace in Jordan by 2100, new research finds, unless the nation implements comprehensive reform, from fixing leaky pipes to desalinating seawater. Jordan's water crisis is emblematic of challenges looming around the world as a result of climate change and rapid population growth.
Physical activity is important in preventing heart and blood vessel disease in young people so long as they don't undertake very strenuous activity on days when air pollution levels are high, according to a nationwide study of nearly 1.5 million people published in the European Heart Journal.
A first-of-its-kind instrument that samples smoke from megafires and scans humidity will help researchers better understand the scale and long-term impact of fires—specifically how far and high the smoke will travel; when and where it will rain; and whether the wet smoke will warm the climate by absorbing sunlight.
Bullying at boarding schools has a negative impact on students' emotional health, but for male students, having a school staff member to rely on for support may mute the harmful effects of bullying, according to a new study. Support networks did not have the same effect for female students, the researchers say.
Studies indicate a link between children's cardiorespiratory fitness and their school performance: the more athletic they are, the better their marks in the main subjects. Similarly, cardiorespiratory fitness is known to benefit cognitive abilities. But what is the real influence of such fitness on school results? Researchers tested pupils from eight Geneva schools. Their results show that there i
Information processing by the brain is altered in depressed individuals. A study conducted at the University of Helsinki found that in depressed patients, the processing of visual perceptions is also different.
Mega-constellations could cause scientists to miss out on crucial discoveries, warn researchers Artificial satellites and space junk orbiting the Earth can increase the brightness of the night sky, researchers have found, with experts warning such light pollution could hinder astronomers' ability to make observations of our universe. There are more than 9,200 tonnes of space objects in orbit arou
Girlhood, Melissa Febos writes in her new essay collection of the same name, is "a darker time for many than we are often willing to acknowledge." The overall impression she creates is a collage of discomfitingly familiar rites of passage, all distinct and yet all tied together by a thread of learned self-abnegation. The book reads at moments like a meme built from various half-buried abuses and
Primary sclerosing cholangitis (PSC) is a rare, chronic, inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched. An international research consortium has now succeeded in identifying a new prognostic factor for PSC from liver biopsies. This is so-called cellular ER stress.
Dwindling water supplies and a growing population will halve per capita water use in Jordan by the end of this century. Without intervention, few households in the arid nation will have access to even 40 liters (10.5 gallons) of piped water per person per day.
Orange Cloud SpaceX launched yet another full-scale prototype of its Mars-bound Starship early Tuesday morning at its test facilities in Boca Chica, Texas. Thanks to heavy fog, we had to watch the ensuing explosion in the form of a lit up orange cloud. The team at NASASpaceflight , who had set up remote cameras to record the events, are now reviewing the footage — and it's not pretty. Rain of Deb
Ancient Egyptians mummified cats, dogs, ibises and other animals, but closer to home in the South American Atacama desert, parrot mummies reveal that between 1100 and 1450 CE, trade from other areas brought parrots and macaws to oasis communities, according to an international and interdisciplinary team.
In a new study, scientists demonstrate that the UK variant to SARS-CoV-2 is neutralized to the same degree as the reference virus (D614G), whereas the South African variant is less sensitive to neutralizing antibodies. To neutralize the South African variant, the antibody concentrations need to be six times higher than for D614G. This difference in sensitivity was also observed in vaccinated indiv
Researchers have developed a new way of using nanomaterials to identify and enrich skeletal stem cells — a discovery which could eventually lead to new treatments for major bone fractures and the repair of lost or damaged bone.
Last spring, Jared Kushner predicted that the coronavirus pandemic would soon end and that the United States would be " really rocking again " by July. Some critics saw his statement, which proved so fatally wrong, as a form of deceit. I saw evidence of something more pitiful: Kushner had fallen prey to optimism bias and availability bias. Optimism clouded his judgment. He wanted things to be bet
A new type of universal computer memory – ULTRARAM™ – has taken a step closer towards development with a successful experiment. 'Universal memory' is a memory where the data is robustly stored, but can also easily be changed; something that was widely considered to be unachievable until now. The new non-volatile RAM, called ULTRARAM™, is a working implementation of so-called 'universal memory', pr
Incarceration is a pervasive issue in the United States that is enormously costly to families, communities, and society at large. The path from prison back to prison may depend on the relationship a person has with their probation or parole officer (PPO). If the relationship lacks appropriate care and trust,…
Heatwaves to double and many properties will be uninsurable if global heating reaches 3C, Australian Academy of Science says Global heating of 3C would more than double the number of annual heatwaves in some parts of Australia, leave properties uninsurable due to flood and fire risk, and make many of the country's ecosystems "unrecognisable", according to Australia's leading scientists. The Austr
A global map of agricultural land across 168 countries has revealed that 64 percent of land used for agriculture and food crops is at risk of pesticide pollution. Almost a third of these areas are considered to be at high-risk.
Researchers have succeeded for the first time in measuring brain waves directly via a cochlear implant. These brainwaves indicate in an objective way how good or bad a person's hearing is. The research results are important for the further development of smart hearing aids.
PLUS. Indflydelsesrige modeller, der bruges af FN og EU-Kommissionen, bruger forældede omkostninger til solceller, der fører til grove underestimater for, hvor stor en rolle, de kan spille i den globale grønne omstilling.
The bicycle is a low-cost means of transport linked to low risk of transmission of infectious disease. During the COVID-19 crisis, governments have therefore incentivized cycling by provisionally redistributing street space. We evaluate the impact of this new bicycle infrastructure on cycling traffic using a generalized difference in differences design….
While Western countries spar over access to the world's vaccine supply, China and Russia have been busy giving away theirs. This distribution of millions of doses, either for free or cheaply, to low- and middle-income nations has been met with skepticism by leaders in the United States and Europe, many of whom have raised concerns over the safety of the jabs, as well as Beijing's and Moscow's mot
Scientists have developed a diagnostic test, which makes use of CRISPR, that can detect the virus that causes COVID-19 even after it has gone through mutations. Since viruses have the ability to evolve over time, a diagnostic test robust against potential mutations is a crucial tool for tracking and fighting the pandemic.
Humans are simply not adapted to space. We evolved in 1G, the amount of gravity near the surface of the Earth, and are well suited to that environment. Spending a lot of time in microgravity, such as aboard the ISS, has a number of physiological effects. Now that some astronauts have been spending long periods of time aboard the ISS, researchers have been better able to understand these effects.
Scientists discover one of the first black holes of its kind. Intermediate mass black holes (100 to 100,000 times the mass of the sun) have only been directly detected once before (LIGO, last year). They form an important link between the smaller black holes left behind after the deaths of stars, and the supermassive black holes which lurk in the hearts of every galaxy. The astrophysicists also fi
A new instrument that samples smoke from megafires and scans humidity will help researchers better understand the scale and long-term impact of fires — specifically how far and high the smoke will travel, when and where it will rain, and whether the wet smoke will warm the climate by absorbing sunlight.
With NASA preparing to send humans to Mars in the 2030s, researchers are studying the physical effects of spending long periods in space. Now a new study by scientists at UT Southwestern shows that the heart of an astronaut who spent nearly a year aboard the International Space Station shrank, even with regular exercise, although it continued to function well.
Commission security proposal would restrict UK access to Horizon Europe quantum computing project Britain will join China in being locked out of research with the EU on cutting-edge quantum technology, such as new breeds of supercomputers, due to security concerns under a European commission proposal opposed by academics and 19 member states. At a meeting on Friday, commission officials said the
Archaeal viruses represent one of the most mysterious parts of the global virosphere, with many virus groups sharing no evolutionary relationship to viruses of bacteria or eukaryotes. How these viruses interact with their hosts remains largely unexplored. Here we show that nonlytic lemon-shaped virus STSV2 interferes with the cell cycle…
Climate labels informing us of a meat product's carbon footprint cause many people to opt for climate-friendlier alternatives. This applies to people who are curious about a product's carbon footprint, as well as to those who actively avoid wanting to know more.
One specific protein may be a master regulator for changing how cancer cells consume nutrients from their environments, preventing cell death and increasing the likelihood the cancer could spread, a study has shown.
Materials such as gallium arsenide are extremely important for the production of electronic devices. As supplies of it are limited, or they can present health and environmental hazards, specialists are looking for alternative materials. So-called conjugated polymers are candidates. These organic macromolecules have semi-conductor properties, i.e. they can conduct electricity under certain conditio
Our solar system is full of comets that whizz by as we track them over centuries. But humans have so far seen only two visiting objects from outside the solar system. There's 'Oumuamua, the interstellar asteroid that we think might actually be a flat pancake-like rock originating from the remains of an exoplanet similar to Pluto. It's so weird that people thought maybe it was an alien spacecraft.
In the discipline of archaeology, harassment is widespread, with archaeologists of color, LGBTQIA+ researchers and scholars with disabilities reporting abuse at much higher rates, according to research presented by Stanford archaeologist Barbara Voss.
Working with fruit flies, scientists say they have identified a new molecular pathway that helps steer moving cells in specific directions. The set of interconnected proteins and enzymes in the pathway act as steering and rudder components that drive cells toward an 'intended' rather than random destination, they say.
A team of researchers has published a comprehensive review of the development of printed electronics. This will enable researchers to address problems within the field of flexible, bendable, stretchable and intelligent electronics.
Those on the left of the political spectrum are more likely than those on the right to notice social inequality, but only when it affects typically disadvantaged groups, a new study from the Kellogg School of Management at Northwestern University has shown.
In a two-year study that could help guide educators developing the post-pandemic new normal, student groups at the assigned to make video presentations showed more creativity and risk-taking than groups making conventional in-person presentations.
While bionic devices are very safe, there has been no standard test for moisture leakage into the devices – until now. Researchers say a standard test will be increasingly important as bionic implants become more common.
Limited water availability, population growth, and climate change have resulted in freshwater crises in many countries. Jordan's situation is emblematic, compounded by conflict-induced population shocks. Integrating knowledge across hydrology, climatology, agriculture, political science, geography, and economics, we present the Jordan Water Model, a nationwide coupled human–natural-engineered syst
Climate change is altering the world we share with all living things. But it's surprisingly difficult to single out climate change as an extinction threat for any one particular species protected under the Endangered Species Act. A new analysis of population data shows that climate change represents a specific extinction threat for an endangered coastal lupine plant.
Younger trees take up and release less water than mature trees 10 years or older, researchers from North Carolina State University found in a new study that tracked how water moves through wetland pine forests near the North Carolina coast.
Our linear model of time may be holding back scientific progress. Spacekime theory can help us better understand the development of diseases, financial and environmental events, and even the human brain. This theory helps us better utilize big data, develop AI, and can even solve inconsistencies in physics. We take for granted the western concept of linear time. In ancient Greece, time was cyclic
New modeling identifies country-specific human and human-influenced environmental factors associated with disease outbreaks. A country's land area, human population density, and area of forest are associated with zoonotic diseases, like COVID-19. Human development index, average annual temperature, and health expenditure predict other kinds of disease.
A reproducibility crisis is ongoing in scientific research, where many studies may be difficult or impossible to replicate and thereby validate, especially when the study involves a very large sample size. Now researchers have developed a statistical tool that can accurately estimate the replicability of a study, thus eliminating the need to duplicate the work and effectively mitigating the reprod
Researchers have revealed the necessary conditions for the robust transport of entangled states of two-photon light in photonic topological insulators, paving the way the towards noise-resistant transport of quantum information.
A doctoral student has identified a long-overlooked pattern in how plants evolved their equivalent of lungs — tiny pores on the surfaces of leaves called stomata. Using specialized imaging techniques and a plant species not often found in laboratories, researchers say this discovery reveals a key difference in the evolution of plants that live on land versus those that can grow in water.
Because Taspase 1 dysregulation is increasingly implicated in the genesis and metastasis of various cancers, it has become an attractive candidate for drug development. But before this can happen, researchers will need a highly detailed blueprint of the structure of this protease. In a new study appearing in the Cell Press journal Structure, researchers from Arizona State University describe their
The childhood memories we retain most searingly tend to involve shame. When I was 6, after being chided twice for talking too loudly during lunch, I was made to stand in the cafeteria by myself until the other kids finished their food. I can't even type that sentence without flushing at how conspicuously bad I felt, and how alone. Humiliation is a kind of trauma; when we experience it, our nervou
The longest corridor in ESA's largest establishment was turned into a test site for one of the Agency's most ambitious future missions, Proba-3. The two satellites making up this mission will line up so that one casts a shadow onto the other, revealing inner regions of the Sun's ghostly atmosphere. But such precision formation flying will only be possible through a vision-based sensor system allow
Editor's Note: Every Tuesday, Abby Freireich and Brian Platzer take questions from readers about their kids' education. Have one? Email them at firstname.lastname@example.org. Dear Abby and Brian, Our 11-year-old son has been in virtual learning since March 2020. It's been a daily struggle, to say the least. He is an only child who is incredibly social, and we can see the isolation taking its toll on h
Many experts believe that the Moon was formed when a protoplanet named Theia crashed into the Earth 4.5 billion years ago. One flaw in the theory has been that there's no remaining sign of Theia. New research suggests that Theia's mantle was subsumed by Earth and that large anomalous blogs of rock deep within the Earth are its remains. They're called "large low-shear-velocity provinces" (LLSVPs),
A team of researchers has developed a new early warning system for vehicles that uses artificial intelligence to learn from thousands of real traffic situations. The results show that, if used in today's self-driving vehicles, it can warn seven seconds in advance against potentially critical situations that the cars cannot handle alone – with over 85% accuracy.
At the start of March, NASA's Curiosity Mars rover began approaching an impressive rock formation that scientists dubbed "Mont Mercou," a nickname taken from a mountain in France. Standing about 20 feet (6 meters) tall, the outcrop is captured in all its majesty in a new selfie, as well as in a pair of panoramas that offer a 3D view. The selfie shows Curiosity in front of Mont Mercou with a new dr
While the quest to explain how Christ can be both fully human and fully divine enjoys a long, fascinating history, Jc Beall, the O'Neill Family Professor of Philosophy at the University of Notre Dame, believes that the quest should end.
Earlier this year, a billionaire named Jared Isaacman announced that he was picking three lucky winners to go to on a free multi-day journey into orbit on board a SpaceX Crew Dragon capsule. Isaacman, who is helping finance the expedition — and will be joining in on the fun himself — announced at the time that he's looking to raise money for childhood cancer research through a raffle. Bone cancer
Could a decades-old antidepressant be a secret weapon against Covid-19? Two recent studies look promising, but drug companies have no incentive to spend millions to test new uses for cheap, off-patent drugs. As a result, efforts to repurpose drugs have fallen to philanthropists.
Sea turtles have been around since dinosaurs roamed the Earth, stretching back about 110 million years. Yet now their existence is at risk, with six of today's seven species classified as threatened or endangered.
A study published in the journal Science and Technology of Advanced Materials summarizes the major achievements made to-date in Heusler alloy research. "Our review article can serve as an ideal reference for researchers in magnetic materials," says Atsufumi Hirohata of the University of York, UK, who specializes in spintronics.
Since the Higgs boson was discovered in 2012, scientists at the Large Hadron Collider (LHC) have been studying the properties of this very special particle and its relation to the fundamental mechanism essential to the generation of mass of elementary particles. One property that remains to be experimentally verified is whether the Higgs boson is able to couple to itself, known as self-coupling. S
Irrigated agriculture is the planet's largest consumer of freshwater and ultimately produces more than 40% of food worldwide. Yet the exact amounts of water actually being used in irrigation remains largely unknown.
Stomata, the gas exchange structures of plants, are formed by the division and differentiation of stem cells, or meristemoids. Although diverse patterns of meristemoid behavior have been observed among different lineages of land plants, the ecological significance and diversification processes of these different patterns are not well understood. Here we…
IIASA researchers have used Sentinel 1 satellite imagery from the European Space Agency to produce a map of the extent and year of detection of oil palm plantations in Indonesia, Malaysia, and Thailand that will help policymakers and other stakeholders understand trends in oil palm expansion while also providing an accurate map for landscape-level planning.
A team of scientists has been using DESY's X-ray source PETRA III to analyze the structural changes that take place in an egg when you cook it. The work reveals how the proteins in the white of a chicken egg unfold and cross-link with each other to form a solid structure when heated. Their innovative method can be of interest to the food industry as well as to the broad field of research surroundi
Thermoelectric technology can generate electricity from waste heat, although their performance can result in a bottleneck for wider applications. Materials scientists can regulate the configurational entropy of a material by introducing different atomic species to tune phase composition and extend the performance optimization space. In a new report now on Science, Binbin Jang et al. used an n-type
We are not venomous, and neither are mice – but within our genomes lurks that potential, suggest scientists The researchers found that the genetic foundation required for oral venom to evolve is present in both reptiles and mammals. The study also provides the first concrete evidence of an underlying molecular link between venom glands in snakes and salivary glands in mammals.
Researchers from AUT BioDesign Lab have developed a prosthetic fin to rehabilitate injured sea turtles. Healthy oceans need sea turtles, but they are unfortunately frequently injured by human factors such as boats and fishing nets, with all seven species now endangered. A damaged fin limits swimming range and survival and prevents female turtles from returning to land to lay eggs. A successful pro
You might think that strumming a guitar without an actual instrument would be like playing soccer without a ball. And back in the day, you may have been right. But now that technology has caught up to the world of music, you can hit those riffs and chords without a guitar string in sight and conjure up some pretty sweet tunes, all thanks to this fabulous innovation . Say hello to the PocketGuitar
In nerve cells the genes encoding for α2δ subunits of voltage-gated calcium channels have been linked to synaptic functions and neurological disease. Here we show that α2δ subunits are essential for the formation and organization of glutamatergic synapses. Using a cellular α2δ subunit triple-knockout/knockdown model, we demonstrate a failure in…
Remote monitoring using airborne devices such as drones or satellites could revolutionize the effectiveness of nature-based solutions (NBS) that protect communities from devastating natural hazards such as floods, storms and landslides, say climate change experts from the University of Surrey.
Study by Office for National Statistics based on data from blood test results Coronavirus – latest updates See all our coronavirus coverage Half of people in the UK now have antibodies against coronavirus, either through infection or vaccination, tests conducted by the Office for National Statistics (ONS) show. According to the most recent coronavirus infection survey , an estimated 54.7% of the
Ever since governments at the 2015 Paris climate summit set 1.5°C as the desired limit for global warming, scientists and journalists alike have regularly asked whether it is achievable. The question arose again recently when the UN published a report of national emission-cutting pledges for the next decade. It will be posed regularly before the publication of the IPCC's Sixth Assessment Report in
Following the selection of the first Scout satellite mission last December, ESA has also given the greenlight to start negotiations with Surrey Satellite Technology Ltd in the UK to lead the development of the second Scout mission—HydroGNSS.
For the first time, researchers have isolated in a controlled laboratory setting the effects of the plasma geometry in its X-ray emission spectrum—the energy distribution of the radiation the plasmas emit.
Sumitomo Rubber Industries, Ltd (SRI) and Tohoku University teamed up to increase the speed of 4-Dimensional Computed Tomography (4D-CT) a thousand-fold, making it possible to observe rubber failure in tires in real-time.
Researchers at the Federal University of São Carlos (UFSCar) in the state of São Paulo, Brazil, have developed a novel far red light-emitting luciferin-luciferase system that is more efficient than those available commercially. An article on the subject is published in the International Journal of Molecular Sciences.
After more than three decades of research, scientists have proven that the cancer affecting up to one in four adult California sea lions necrospied at The Marine Mammal Center in Sausalito, CA, is caused by a sexually transmitted herpesvirus. The cancer, known as sea lion urogenital carcinoma, has clear parallels to cervical cancer in humans and provides a helpful model for human cancer study.
Giant trees in tropical forests, witnesses to centuries of civilization, may be trapped in a dangerous feedback loop according to a new report in Nature Plants from researchers at the Smithsonian Tropical Research Institute (STRI) in Panama and the University of Birmingham, U.K. The biggest trees store half of the carbon in mature tropical forests, but they could be at risk of death as a result of
Pink Floyd's Dark Side of the Moon cover, voted the greatest classical rock album of all time, intended to portray the prism and dispersion of light into a rainbow as a certain metaphorical symbolism and a light show that was never celebrated. However, they really were not aware of the fact that this image would be used by many to help illustrate the concept of refractive index and how light chang
Scientists think that climate change may have greater impact the largest trees in tropical forests, and the death of these giants has a major impact on the forest, but because these monumental trees are few and far between, almost nothing is known about what causes them to die.
New observations indicate that the rogue comet 2I/Borisov, which is only the second and most recently detected interstellar visitor to our Solar System, is one of the most pristine ever observed. Astronomers suspect that the comet most likely never passed close to a star, making it an undisturbed relic of the cloud of gas and dust it formed from.
FrankenBacteria The first-ever bacteria with a genetic code engineered entirely from scratch in a lab is now growing, splitting, and multiplying just like any unicellular organism found in nature. National Institute of Standards and Technology scientists (NIST) first developed the bacteria JCVI back in 2010, according to a press release on the project. Since then, it's been a matter of improving
Observational studies have linked cannabis use to an array of negative outcomes, including psychiatric symptoms, cognitive impairment, and educational and occupational underachievement. These associations are particularly strong when cannabis use occurs in adolescence. Nevertheless, causality remains unclear. The purpose of the present study was thus to examine associations between prospectively..
What role do ideologically extreme media play in the polarization of society? Here we report results from a randomized longitudinal field experiment embedded in a nationally representative online panel survey (N = 1,037) in which participants were incentivized to change their browser default settings and social media following patterns, boosting…
CRISPR/Cas9 has emerged as a powerful technology for tissue-specific mutagenesis. However, tissue-specific CRISPR/Cas9 tools currently available in Drosophila remain deficient in three significant ways. First, many existing gRNAs are inefficient, such that further improvements of gRNA expression constructs are needed for more efficient and predictable mutagenesis in both somatic and…
Tough soft materials usually show strain softening and inelastic deformation. Here, we study the molecular mechanism of abnormally large nonsoftening, quasi-linear but inelastic deformation in tough hydrogels made of hyperconnective physical network and linear polymers as molecular glues to the network. The interplay of hyperconnectivity of network and effective load…
NKCC1 is the primary transporter mediating chloride uptake in immature principal neurons, but its role in the development of in vivo network dynamics and cognitive abilities remains unknown. Here, we address the function of NKCC1 in developing mice using electrophysiological, optical, and behavioral approaches. We report that NKCC1 deletion from…
Temperature-dependent regulation of ion channel activity is critical for a variety of physiological processes ranging from immune response to perception of noxious stimuli. Our understanding of the structural mechanisms that underlie temperature sensing remains limited, in part due to the difficulty of combining high-resolution structural analysis with temperature stimulus. Here,…
Ultrafast structural dynamics with different spatial and temporal scales were investigated during photodissociation of carbon monoxide (CO) from iron(II)–heme in bovine myoglobin during the first 3 ps following laser excitation. We used simultaneous X-ray transient absorption (XTA) spectroscopy and X-ray transient solution scattering (XSS) at an X-ray free electron laser…
The synaptonemal complex is a tripartite proteinaceous ultrastructure that forms between homologous chromosomes during prophase I of meiosis in the majority of eukaryotes. It is characterized by the coordinated installation of transverse filament proteins between two lateral elements and is required for wild-type levels of crossing over and meiotic progression….
microRNA-218 (miR-218) has been linked to several cognition related neurodegenerative and neuropsychiatric disorders. However, whether miR-218 plays a direct role in cognitive functions remains unknown. Here, using the miR-218 knockout (KO) mouse model and the sponge/overexpression approaches, we showed that miR-218-2 but not miR-218-1 could bidirectionally regulate the contextual and…
Nondipolar magnetic fields exhibited at Uranus and Neptune may be derived from a unique geometry of their icy mantle with a thin convective layer on top of a stratified nonconvective layer. The presence of superionic H2O and NH3 has been thought as an explanation to stabilize such nonconvective regions. However,…
The Invar anomaly is one of the most fascinating phenomena observed in magnetically ordered materials. Invariant thermal expansion and elastic properties have attracted substantial scientific attention and led to important technological solutions. By studying planar faults in the high-temperature magnetically disordered state of Ni1−cFec, here we disclose a completely different…
Meprin β (Mβ) is a multidomain type-I membrane metallopeptidase that sheds membrane-anchored substrates, releasing their soluble forms. Fetuin-B (FB) is its only known endogenous protein inhibitor. Herein, we analyzed the interaction between the ectodomain of Mβ (MβΔC) and FB, which stabilizes the enzyme and inhibits it with subnanomolar affinity. The…
The atomic structure of the complete myosin tail within thick filaments isolated from Lethocerus indicus flight muscle is described and compared to crystal structures of recombinant, human cardiac myosin tail segments. Overall, the agreement is good with three exceptions: the proximal S2, in which the filament has heads attached but…
Novel many-body and topological electronic phases can be created in assemblies of interacting spins coupled to a superconductor, such as one-dimensional topological superconductors with Majorana zero modes (MZMs) at their ends. Understanding and controlling interactions between spins and the emergent band structure of the in-gap Yu–Shiba–Rusinov (YSR) states they induce…
Quality control requires discrimination between functional and aberrant species to selectively target aberrant substrates for destruction. Nuclear RNA quality control in Saccharomyces cerevisiae includes the TRAMP complex that marks RNA for decay via polyadenylation followed by helicase-dependent 3′ to 5′ degradation by the RNA exosome. Using reconstitution biochemistry, we show…
Rift Valley fever virus (RVFV), an emerging arboviral and zoonotic bunyavirus, causes severe disease in livestock and humans. Here, we report the isolation of a panel of monoclonal antibodies (mAbs) from the B cells of immune individuals following natural infection in Kenya or immunization with MP-12 vaccine. The B cell…
Recent findings regarding nicotinamide adenine dinucleotide (NAD+)-capped RNAs (NAD-RNAs) indicate that prokaryotes and eukaryotes employ noncanonical RNA capping to regulate gene expression. Two methods for transcriptome-wide analysis of NAD-RNAs, NAD captureSeq and NAD tagSeq, are based on copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry to label NAD-RNAs. However, copper ions
The use of photoswitchable fluorescent diarylethenes (fDAEs) as protein labels in fluorescence microscopy and nanoscopy has been limited by labeling inhomogeneity and the need for ultraviolet light for fluorescence activation (on-switching). To overcome these drawbacks, we prepared "turn-on mode" fDAEs featuring thienyl substituents, multiple polar residues, and a reactive maleimide…
Genetic screens can identify synthetic lethal (SL) interactions and uncover potential anticancer therapeutic targets. However, most SL screens have utilized knockout or knockdown approaches that do not accurately mimic chemical inhibition of a target protein. Here, we test whether missense mutations can be utilized as a model for a type…
Research led by The Marine Mammal Center finds that a specific strain of herpesvirus triggers cervical cancer affecting nearly 1 in 4 necropsied California sea lions. The findings show that sea lions are a critical model for understanding how cancer develops with important parallels to human cancer research.
Brenna Morse, a UMass Lowell graduate and current nurse of children with complex conditions who has been a faculty member in the Solomont School of Nursing since 2015, and a team of researchers from Boston Children's Hospital have developed a method through which health-care providers can more readily identify the medical issue being experienced by a child who cannot communicate it on their own.
Nature, Published online: 26 March 2021; doi:10.1038/d41586-021-00849-8 Oxford-AstraZeneca vaccine's rollercoaster ride of a week might be coming to a welcome end. Plus, the first known gene transfer from plant to insect and watch an octopus change colour during active sleep.
Researchers quantify the specific interaction between the spike protein of SARS-CoV-2 — the virus that causes COVID-19 — with the ACE2 receptors in human cells that may partially explain its high infection rate compared to SARS-CoV-1.
Preclinical research from VCU Massey Cancer Center published recently in the Proceedings of the National Academy of Sciences shows that the combination of two existing drugs can exploit the metabolic "hunger" of a particularly aggressive type of neuroblastoma to kill cancer cells without inflicting too much collateral damage to healthy tissue.
Mount Sinai researchers have found that a widely available and inexpensive drug targeting inflammatory genes has reduced morbidity and mortality in mice infected with SARS-CoV-2, the virus that causes COVID-19.
As the pandemic stretches health care workers ever thinner, an IT specialist and a physician-wellness expert teamed up to tackle a major cause of burnout — patient records. The study recommends specific ways to lighten the records load and protect doctors from burnout.
There's nothing more annoying than your phone dying at an inopportune time. However, when you're at work, or running errands, or working out at the gym, a dead phone battery is really just an inconvenience. And at least you have a few options to deal with it. You might be able to find an outlet and charge it for a few minutes, or maybe you can charge while you drive from the grocery store to the
In order to enable large-scale hydrogen production using solar energy, particulate photocatalysts are being researched as a simple and cost-effective solution to splitting water into hydrogen and oxygen. It is necessary to develop a photocatalyst that can efficiently use visible light, which accounts for a large part of solar energy, in the water decomposition reaction. Barium tantalum oxynitride
Researchers have optimized a process to convert waste from rubber tires into graphene that can strengthen concrete. The environmental benefits of adding graphene to concrete are clear, says chemist James Tour. " Concrete is the most-produced material in the world, and simply making it produces as much as 9% of the world's carbon dioxide emissions," says Tour, professor of computer science and of
The first deep-learning software was developed as a versatile tool for tracking cells and extracting their signals from ~100 cells in a moving worm brain, in a zebrafish heart, and ~1,000 cultured cancer cells in 3D microscope videos. The method demonstrates significant improvements in tracking capabilities on various metrics including the possible number of tracked objects, robustness, and comput
Gas hydrates are a solid compound of gases and water that have an ice-like structure at low temperatures and high pressures. Compounds of methane and water, so-called methane hydrates, are found especially at many ocean margins—also in the Black Sea. In addition to a possible use as an energy source, methane hydrate deposits are being investigated for their stability, as they can dissolve with cha
Researchers from Newcastle University, UK, working with colleagues at King Mongkut's University of Technology Thonburi (KMUTT) in Thailand and the Institute of Urban Environment of the Chinese Academy of Sciences, analyzed samples of water and sediment taken from aquaculture ponds and nearby canals at five locations in central Thailand's coastal region.
In a new study published in Conservation Science and Practice, researchers at the University of Maryland (UMD) partnered with Indonesian experts to explore the motivations and challenges of women pursuing a career in conservation sciences in Indonesia. Given that Indonesia is one of the most biodiverse countries on the planet but is simultaneously experiencing extreme rates of deforestation, it is
New research suggests that these increased hours spent online may be associated with cyberbullying behaviors. According to a study by the University of Georgia, higher social media addiction scores, more hours spent online, and identifying as male significantly predicted cyberbullying perpetration in adolescents.
Physicists from the University of Sussex have developed an extremely thin, large-area semiconductor surface source of terahertz, composed of just a few atomic layers and compatible with existing electronic platforms.
As our planet warms, seas rise and catastrophic weather events become more frequent, action on climate change has never been more important. But how do you convince people who still don't believe that humans contribute to the warming climate?
Superconductivity is known to be easily destroyed by strong magnetic fields. NIMS, Osaka University and Hokkaido University have jointly discovered that a superconductor with atomic-scale thickness can retain its superconductivity even when a strong magnetic field is applied to it. The team has also identified a new mechanism behind this phenomenon. These results may facilitate the development of
Once again, what's going on with vascular events and the AZ/Oxford vaccine? I last wrote about this situation a couple of weeks ago, and it's taken some real turns since then. At that point several EU countries had suspended dosing, but over the next week several began administering the vaccine again after the European Medicines Agency recommended it, in some cases with advisories about which age
Vaccineringen mot covid-19 är i full gång. Här har vi samlat alla artiklar från Forskning.se om vaccinationer i allmänhet och vaccin mot corona i synnerhet. Vaccineringen mot covid-19 har lett till ett ökat intresse för vacciner i allmänhet. Vad händer i kroppen när man vaccineras? Vad innehåller vaccin mot corona – mer än sin verksamma substans? Hur skulle världen ha sett ut om inte vacciner fan
Researchers at the University of Maryland (UMD) partnered with Indonesian experts to explore the motivations and challenges of Indonesian women pursuing a career in conservation sciences. Indonesia is one of the most biodiverse countries on the planet but is simultaneously experiencing extreme rates of deforestation. With more diverse voices representing global conservation, the country and others
Many previous studies have linked increased maternal body weight and unhealthy diets to poorer metabolic outcomes in offspring, often many years later. Understanding the mechanisms of how maternal exercise can reverse these effects might lead to interventions that prevent these diseases transmitting across generations,
Elizabeth Fast, an associate professor of applied human sciences in the Faculty of Arts and Science, wanted to help Indigenous youth reconnect with their cultures in safe and accessible ways. Along with a youth advisory group composed of Indigenous youth (some of whom are also students), she has been organizing a series of land-based learning retreats revolving around Indigenous traditions and cer
When variants of SARS-CoV-2 emerged, concern arose that they might elude protective immune responses generated by prior infection or vaccination, potentially making re-infection more likely or vaccination less effective. NIAID researchers and colleagues analyzed blood cell samples from 30 people who had contracted and recovered from COVID-19 prior to the emergence of virus variants. They found tha
Parents who are exposed to predators pass on information about risky environments to their offspring through changes in gene expression—but how that information affects offspring differs depending on the sex of the parent. My colleagues and I showed this using sticklebacks—a small species of freshwater fish whose brightly colored males care for developing eggs—in a series of papers recently publis
Whether you are a seasoned astronomer or new to stargazing, we'd like to see your photos from the last few weeks Have you taken a recent photograph of the cosmos that you're particularly proud of? Whether you are a seasoned astronomer or new to stargazing, we would like to hear from you. Continue reading…
People are adept at discerning most of the different emotions that underlie screams, such as anger, frustration, pain, surprise or fear, finds a new study by psychologists at Emory University. Screams of happiness, however, are more often interpreted as fear when heard without any additional context, the results show.
Physicists from the University of Sussex have developed an extremely thin, large-area semiconductor surface source of terahertz, composed of just a few atomic layers and compatible with existing electronic platforms.
Through his role on the US Preventive Services Task Force, UVA Health's Li Li, MD, Ph.D., MPH, has helped develop new lung cancer screening guidelines that expand screenings to more high-risk patients.
Researchers in KU's School of Education and Human Sciences observed the use of critical race media literacy in a high school class, noted the high levels of critical thinking students used to address racism and sexism in super hero movies, and argue all manner of schools can and should use similar methods.
In a randomized clinical trial published in the journal PAIN, researchers found participants with moderate to severe irritable bowel syndrome (IBS) who were knowingly treated with a pharmacologically inactive pill — referred to as an honest or open-label placebo — reported clinically meaningful improvements in their IBS symptoms.
Physician leaders of radiation therapy clinics say that new patients are arriving for treatment with more advanced disease than before the COVID-19 pandemic, according to a new survey from the American Society for Radiation Oncology (ASTRO). The national survey fielded Jan. 15-Feb. 7 also found that treatment postponements and deferrals have largely subsided and that clinics continue to use a vari
As biofuels continue to present challenges, microalgae are gaining momentum as a biofuel energy crop. In the Journal of Renewable and Sustainable Energy, researchers show how a combination of monochromatic red and blue LED illumination on one type of microalga can enhance its growth and increase the biosynthesis of critical components, such as lipids, for microalgae feedstock development. The rese
Emerging technologies can screen for cervical cancer better than Pap smears and, if widely used, could save lives in areas where access to health care may be limited. In Biophysics Reviews, scientists at Massachusetts General Hospital write advances in nanotechnology and computer learning are among the technologies helping develop HPV screening that take the guesswork out of the precancer tests. T
Lockdown significantly affected our health (for good and bad), our work and how we socialize. These consequences have been widely discussed, but far less attention has been given to the effect on our sex lives.
Over the past decade, selfies have become a mainstay of popular culture. If the #selfie hashtag first appeared in 2004, it was the release of the iPhone 4 in 2010 that saw the pictures go viral. Three years later, the Oxford English Dictionary crowned "selfie" word of the year.
Farmers stand at the center of the world, says Andrew Youn, cofounder of One Acre Fund, an agricultural organization that's empowering sub-Saharan farm families with the loans, seeds, fertilizer and training needed to increase crop yields and end hunger. Meet Therese Niyonsaba, a Rwandan farmer who shares how the program helped her family prosper, and learn more about One Acre Fund's goal to lead
An international research team, including biologists from St Petersburg University, has identified a transmissible cancer lineage in the Far Eastern mussels. The disease can have an adverse effect on the populations of these molluscs, which are extensively farmed in Russia.
Since the start of the pandemic, there have been more than 492,000 documented cases of COVID-19 among inmates and staff in US prisons, jails, and detention centers, according to the COVID Prison Project. That's nearly as many cases as in the entire state of Minnesota. Further, there have been more than 2,500 deaths due to the coronavirus. As high as they are, these numbers are likely an undercoun
Education is considered one of the most critical personal capital investments. But formal educational attainment doesn't necessarily pay off in job satisfaction, according to new research from the University of Notre Dame.
A research team from Ruhr-Universität Bochum (RUB) and McGill University in Montreal is investigating what exactly happens underground when the earth in western Canada shakes as a result of hydraulic fracturing activities. The team, headed by Bochum-based Professor Rebecca Harrington, wants to fundamentally understand how earthquakes occur—whether human induced or natural. "The hydraulic fracturin
Scientists are developing tools to observe the biological machinery in in vivo animal models to be able to understand and better treat severe brain diseases like Alzheimer's disease and many other conditions. Holographic endoscopes attracted researchers' interest because of their potential to conduct minimally invasive observations inside the human body.
Scientists have been using DESY's X-ray source PETRA III to analyse the structural changes that take place in an egg when you cook it. The work reveals how the proteins in the white of a chicken egg unfold and cross-link with each other. The method can be of interest to the food industry as well as to the broad field of protein research, as the groups report in the journal Physical Review Letters.
Scientists have discovered that tracking malaria as it develops in humans is a powerful way to detect how the malaria parasite causes a range of infection outcomes in its host.The study, found some remarkable differences in the way individuals respond to malaria and raises fresh questions in the quest to understand and defeat the deadly disease.
Researchers at Delft University of Technology (TU Delft) have expanded upon a clever trick and increased the speed of electron microscope imaging by a factor of 20. A simple adjustment is all that is needed: applying a voltage to the specimen holder. Through this simple intervention, a specimen that would normally take an electron microscope a week to image can now be inspected in a single night o
CEST researchers have uncovered novel insight/results about surface functionalization of materials used in a wide range of applications, such as energy storage, biochemistry, sensing, and energy production
Water quality management in the ocean often targets visible pollution sources such as sewage, rivers or ships. A new global study, led by researchers at the University of Gothenburg, reveals that invisible groundwater discharges may be just as important driving nitrogen into coastal waters.
Gregory Norris is an expert on quantifying firms' impacts on the environment over the life cycles of their products and processes. His analyses help decision-makers opt for more sustainable, Earth-friendly outputs.
Like moths to a flame, spotted lanternflies are visually drawn toward and seemingly captivated by vertical objects such as utility poles, a behavior that could be valuable in predicting where the pests might be heading, according to entomologists in Penn State's College of Agricultural Sciences.
A growing number of young people are identifying as part of the LGBTQ+ community, and many are challenging binaries in gender and sexual identity to reflect a broader spectrum of experience beyond man or woman and gay or straight. But not everyone is participating equally in these diverse forms of expression, according to new research from the University of California, Santa Cruz.
Heat waves, which are projected to become more frequent and intense as the century progresses, could cause as much as 10 times more crop damage than is now projected, a team of researchers led by the University of Colorado Boulder has found.
Ten years on from the 2009 Victorian Black Saturday fires, in which 173 people died, 3,500 buildings were destroyed and entire townships were wiped out, about two thirds of people from highly impacted communities reported they felt "mostly" or "fully recovered."
A new report examines the current situation and the challenges for online advertising. The results reveal an online market that is increasingly dominated by just a few companies (e.g., Google, Facebook) which occupy strategic roles throughout the advertising chain, affecting free competition.
Babies can recognise combinations of words even before they have uttered their first word, a study suggests, challenging ideas of how children learn language. Assessments in 11-12 month-olds show that infants at the cusp of talking are already processing multiword phrases such as 'clap your hands'.
DALLAS – March 30, 2021 – UT Southwestern researchers have identified factors that put patients with childhood-onset lupus at elevated risk for poor outcomes, such as end-stage renal disease or death, as they transition from pediatric to adult health care. The findings, published online in Seminars in Arthritis and Rheumatism, emphasize the precarious nature of this period and shine a spotlight on
An international research team, including biologists from St Petersburg University, has identified a transmissible cancer lineage in the Far Eastern mussels. The disease can have an adverse effect on the populations of these molluscs, which are extensively farmed in Russia.
Recent incidents of racial discrimination and violence against Asians and Asian-Americans in the United States have prompted critical discussions about how to talk about such biases with younger age groups. New research from the University of Kansas shows using critical race media literacy, or examining how race and gender are addressed in popular culture, can be an effective way to discuss those
A study examining bean productivity among smallholder farmers in Tanzania, has found that on average, yields are 6% lower among female than male farmers. Women are often 'invisible' in agriculture, researchers say, due to social structural barriers and national agricultural policies, which do not address discriminatory land rights; education and agricultural information and decision making, which
Since the mid-1990s, new approaches to poverty reduction have been introduced in countries across Africa, Asia and Latin America. Some have involved income transfer programs that target poorer citizens based on various means tests. Most have targeted female caregivers, primarily mothers.
A new method for monitoring biopharmaceutical product quality was recently put to the test by The National Institute of Standards and Technology (NIST) and 28 laboratories representing the biopharmaceutical industry, instrument and software vendors, and the federal government. The results of this interlaboratory study were recently published in the Journal of the American Society for Mass Spectrom
A staggering 6.5 billion chicks are killed worldwide every year. These are generally male chicks that are of no economic value. In Ovo has developed technology that can quickly determine the sex of a chick, to ensure that only female chicks are hatched. The first 150,000 chicks have now hatched in this animal-friendly process.
Researchers studied cannibalism among commonly-found moths to test an evolutionary principle. The scientists concluded that moths with more sibling interaction were less selfish. The principle applies to humans and other animals. A common moth, found in pantries, could explain a crucial link between society and selfishness, according to a new study. Researchers showed that an increase in sibling
Failure to comply with international exposure recommendations for air pollution, noise, heat and access to green space is associated with more than 1,000 deaths per year in Barcelona and more than 900 in Madrid, accounting for 7% and 3% of overall premature mortality, respectively.
When the coronavirus pandemic hit the world in the spring of 2020, feelings of being capable or efficacious against the virus were a key factor in driving compliance with the authorities' guidelines. This is the result of a new study based on large surveys across eight Western democracies, published in British Journal of Health Psychology.
PLUS. Kun fem procent af alle STEM-jobopslag inden for de seneste seks år går efter nyuddannede. Arbejdsgivere må tage et større ansvar for at hyre nyuddannede, mener IDA, men arbejdsgiverorganisation har svært ved at genkende billedet.
As Americans emerge from the COVID-19 pandemic, two mass shootings within a week have made clear the reality of the other US epidemic: gun violence. On March 16, a gunman killed eight people at three Atlanta-area massage businesses, and on March 22, 10 people were gunned down in a Boulder, Colorado grocery store. Here, John J. Donohue, III , who was an expert witness for the city of Boulder in it
Even after scientific papers are retracted, hundreds of studies cite them as evidence. Roughly four retractions occur per 10,000 publications, mostly in medicine, life sciences, and chemistry journals. Journals should implement control measures that block the publication of papers that cite retracted papers. Andrew Wakefield's 1998 study linking vaccines with autism was riddled with holes. All 12
Thanks to neural implants, mind reading is no longer science fiction . As I'm writing this sentence, a tiny chip with arrays of electrodes could sit on my brain, listening in on the crackling of my neurons firing as my hands dance across the keyboard. Sophisticated algorithms could then decode these electrical signals in real time. My brain's inner language to plan and move my fingers could then
GAN som står för Generative Adversarial Networks är en AI-metod som bland annat kan skapa verklighetstrogna foton eller filmer på uppdiktade människor. Forskare vid avdelningen för systembiologi på Chalmers tekniska högskola i Göteborg har använt samma teknik för att designa nya proteiner.
Researchers from the University of Tsukuba discovered a novel mechanism by which the brain regulates the cardiovascular system in response to stress. By electrically stimulating the lateral habenula, the researchers found that it regulates heart rate and blood pressure via the autonomic nervous system. They then showed that this effect depends on specific receptor subtypes of the neurotransmitter
Listeners of high-energy music such as hard rock and hip-hop may be given less accurate music recommendations by music recommender systems than listeners of other non-mainstream music, according to research published in the open access journal EPJ Data Science.
Chen-Yu Zhang's group reprogram host liver with genetic circuits to direct the synthesis and self-assembly of siRNAs into secretory exosomes. In vivo assembled siRNAs are systematically distributed to multiple tissues or targeted to specific tissues (e.g., brain), inducing potent target gene silencing in these tissues. The therapeutic value of this strategy is demonstrated in a variety of diseases
Replacing regular common salt consumed by hypertensive patients in rural areas with a salt substitute can have a significant impact in terms of lowering their blood pressure, a new study by The George Institute for Global Health has revealed.
As allegations of rape and sexual assault engulf Australian federal politics, several current and former female staffers and politicians have come forward to share their stories of a culture of toxic masculinity within Australia's political bubble.
Studying narwhal tusks reveals that their diet and exposure to pollution have shifted over the past half century in response to sea-ice decline. Human emissions have also led to a sharp rise in the presence of mercury in recent years, the researchers report. In the Arctic, climate change and pollution are the biggest threats to top predators like narwhals. "Our research shows that climate change
Apologies if these kinds of posts are not allowed but I don't see a rule against them. I am in need of more male (aged 18+) participants for my research project study due to a gender imbalance in my current sample. I am having no luck on the SampleSizes and main Psychology subreddits, probably due to the massive volume of other study requests. I'm a psychology student in Ireland and I need about
There are some concept I try so hard to understand and do so much research, but just can't fathom. It gets so annoying and I feel insecure when I ask people to explain certain things and I still don't get it. submitted by /u/SpriteKid [link] [comments]
Using audio-enhanced, interactive, pre-recorded storybooks can improve the vocabulary of at-risk preschoolers, a new study shows. That's good news for getting a vulnerable population of children ready for school. "While we are working with children who are only 4 or 5 years old, we teach them the vocabulary words they will need to know when they eventually enter elementary or middle school," says
Every day, millions of people rely on stimulants like Adderall to help them maintain attention and stay focused on tasks. Unfortunately, while these stimulants work well, they often come with a lot of side effects. Moreover, when you use them for a prolonged period of time, you start to build up a tolerance. And unless you can find a way to reduce that tolerance, you'll be forced to up your dosag
New Research from the University of California, Santa Cruz shows how regional differences and other social factors affect expression of diversity in sexual and gender identity among teens and young adults.
1) Spatial Inequities in COVID-19 Testing, Positivity, Confirmed Cases and Mortality; 2) Injustice in Health: Now Is the Time to Change the Story; 3) Toward Understanding COVID-19 Recovery: National Institutes of Health Workshop on Postacute COVID-19; 4) Update Alert 8: Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers
Young people's choice of upper secondary school is strongly affected by their gender and their parents' educational background. Instead of reducing this division, the reforms that have been implemented in recent decades have actually resulted in an increase. This is shown in a new dissertation from the University of Gothenburg.
Det finns ett 40-tal grundläggande, eller basala, ord som är snarlika i nästan hela världen. Specifikt handlar det om språkljud som återkommer gång på gång, till exempel orden för mamma och pappa, som tenderar att innehålla m- respektive p-ljud. Andra ord är bland annat ben, aska, stor och liten.
Sharing household roles can promote gender and income equality within households, but research suggests it could also increase inequality between households. The new study asks: How do people's marriage choices affect the labor market, and ultimately gender wage gaps and income inequality? Despite achieving gradual progress closing gender gaps in recent decades, women around the world still lag b
Boston Dynamics has spent years posting creepy videos of lifelike robots, but it started selling its first real product last year in the form of a $75,000 robot dog called Spot . Now, the company has unveiled its second production model robot, and the first designed for commercial warehouse applications. It's called Stretch, and you'll be able to buy one next year. You might want to start saving
Our need for data centers is almost bottomless, and their resource demands are equally huge. For example, keeping these racks of servers from melting in the heat of their own processing requires so much cooling, Microsoft tried submerging them in the ocean . That said, learning the electrical engineering behind them is a great way to start a new career, or learn how to build a better server farm
"the Committee believes that when carelessness or scientific dishonesty can be found in so many articles with so many different authors in question, there must be a lack of training and / or lack of control over data handling. The committee therefore believes that it is qualified probability that there has been an institutional system error when it comes to training. The committee believes that go
En 26-årig mand er varetægtsfængslet for at have stjålet intime billeder og videoer af over 500 piger og kvinder. Han har har hacket sig adgang til både mail- og Snapchat-konti for at få adgang til materialet.
A paper arguing that conventional methods of calculating ocean currents are flawed has been retracted because its own calculations ran aground. The article, "A Complete Formula of Ocean Surface Absolute Geostrophic Current," was written by Peter Chu, of the Naval Ocean Analysis and Prediction Laboratory, part of the Naval Postgraduate School in Monterey. Chu is … Continue reading
Att investera med hjälp av lånade pengar, så kallad hävstång, kan ge höga vinster men också stora förluster. En avhandling från Handelshögskolan i Umeå undersöker om det finns en optimal nivå av hävstång. I sin avhandling har Christian Lundström Tjurhufvud analyserat vinsten från två typer av handelsstrategier på börsen: handelsstrategier baserade på så kallad teknisk analys och den långsiktiga v
Ungdomars gymnasieval är fortfarande starkt präglat av kön och föräldrarnas utbildningsbakgrund. De reformer som genomförts de senaste decennierna har snarare ökat uppdelningen och bidragit till segregation. – I skuggan av samhällsdebatten om det fria skolvalet fortsätter valet av program och ämnen på gymnasiet att bidra till segregation och uppdelning av elever. Gymnasieskolan är extremt könsseg
Nature Communications, Published online: 30 March 2021; doi:10.1038/s41467-021-22233-w The relationship between Mott state and charge density wave state in two dimensional materials remains unclear. Here, Liu et al. reveal spatial distribution of a Mott-Hubbard band in monolayer 1T-NbSe2 forming a new periodic pattern in addition to the well-known CDW pattern.
Nature Communications, Published online: 30 March 2021; doi:10.1038/s41467-021-22271-4 Suppressing 1/f-shaped low-frequency noise is critical but fundamentally challenging to both electrical and optical transducers. Here, the authors demonstrate a 1/f-noise-free optical sensor with integrated CMOS-compatible heterodyne interferometer and an upconversion amplifying technique, which suppresses the
Nature Communications, Published online: 30 March 2021; doi:10.1038/s41467-021-22133-z Concominant structural and electronic phase transitions in the excitonic insulator candidate Ta2NiSe5 make the identification of the driving mechanism of the transition challenging. Here, the authors report evidence for electronically-driven transition via Raman susceptibility measurements.
Nature Communications, Published online: 30 March 2021; doi:10.1038/s41467-021-22251-8 Tomographic reconstructions of cryopreserved specimens enable in-situ structural studies. Here, the authors present the beam image-shift electron cryo-tomography (BISECT) approach that accelerates data collection speed and improves the map resolution compared to earlier approaches and present the in vitro struc
Nature Communications, Published online: 30 March 2021; doi:10.1038/s41467-021-21226-z In genome-wide association meta-analysis, it is often difficult to find an independent dataset of sufficient size to replicate associations. Here, the authors have developed MAMBA to calculate the probability of replicability based on consistency between datasets within the meta-analysis.
Nature Communications, Published online: 30 March 2021; doi:10.1038/s41467-021-22139-7 The molecular processes that lead to neuroendocrine prostate cancer after treating prostate adenocarcinoma (PRAD) are not well understood. Here the authors show that regulation by FOXA1 and changes in the epigenomic profile drive the transition from PRAD to a neuroendocrine phenotype.
Nature Communications, Published online: 30 March 2021; doi:10.1038/s41467-021-22177-1 Here the authors report the results of randomized, single-blind, placebocontrolled trial on the effects of a asingle subcutaneous dose of Peginterferon Lambda-1a (Lambda) in 120 outpatients with mild to moderate COVID-19, showing that while treatment is well tolerated it does not shorten the duration of SARS-Co
BioNyt Videnskabens Verden (www.bionyt.dk) er Danmarks ældste populærvidenskabelige tidsskrift for naturvidenskab. Det er det eneste blad af sin art i Danmark, som er helliget international forskning inden for livsvidenskaberne.
Bladet bringer aktuelle, spændende forskningsnyheder inden for biologi, medicin og andre naturvidenskabelige områder som f.eks. klimaændringer, nanoteknologi, partikelfysik, astronomi, seksualitet, biologiske våben, ecstasy, evolutionsbiologi, kloning, fedme, søvnforskning, muligheden for liv på mars, influenzaepidemier, livets opståen osv.
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