Heads of man, woman and child found on site of Stoke Mandeville church built in 1080 and abandoned 800 years later Roman statues of a man, woman and child have been uncovered by archaeologists at an abandoned medieval church on the route of the HS2 high-speed railway. The discovery was "utterly astounding", according to Rachel Wood, the lead archaeologist at the site in Stoke Mandeville, Buckingh
Melbourne and Victoria's regions reunited and major events to be held at Flemington Racecourse and Sidney Myer Music Bowl Victorian Covid restrictions: what rules and regulations have changed? Vaccine rollout tracker ; cases and data tracker Biden admits to Macron the US was 'clumsy' in Aukus submarine deal Get our free news app ; get our morning email briefing There have been 236 new locally-acq
Thanks to algorithms that learn about social media users' content preferences, Facebook timelines, Twitter feeds, suggested YouTube videos, and other news streams can look startlingly different from one person's online account to the next. Media and communication experts often wrestle with how to rein in the forces that further polarize people with different views, especially people who sit on opp
How can rural producers in Rwanda better produce chicken for both household consumption and profit? University of Tennessee researchers are suggesting a hybrid model for the Rwandan broiler industry, among other improvements, in a new journal article.
The loss of seagrass habitat caused a dramatic shift in fish species in Morro Bay. Areas once covered with lush seagrass meadows and unique fish species are now home to muddy-seafloor-loving flatfish, according to a paper by Cal Poly researchers published in the October 2021 print edition of Estuaries and Coasts.
Unlike meerkats that take individual turns watching for predators while the rest forage, Barbary ground squirrels found off the coast of Africa stand sentry together — a behavior called synchronous vigilance, according to a new study.
Graduate students planned a three-day-long strike to demand fair pay, union security, and improved protections against sexual harassment and discrimination. If an agreement isn't met, the union says they may strike longer, potentially disrupting university research.
These days, you can play modern video games in a car's dashboard , but it wasn't so long ago that video games were confined to huge bulky consoles in the den. If you're missing that feeling of playing a 2D classic on the rug downstairs, the Mini Game Entertainment System with 620 Built-In Classic Games brings back that feeling, in a much smaller package. The Feeling You Remember As you can see ab
Emailmancer Influential sci-fi author William Gibson, widely credited with coining the term "cyberspace" and imagining an ahead-of-its time vision of the internet back in his 1984 novel "Neuromancer," is having computer trouble. "Current contact info," he tweeted today . "If you email me, I receive it, but a glitch is making it impossible for me to email you my reply. If you text me at my usual n
Quantum physicists are reporting an international achievement for Denmark in the field of quantum technology. By simultaneously operating multiple spin qubits on the same quantum chip, they surmounted a key obstacle on the road to the supercomputer of the future. The result bodes well for the use of semiconductor materials as a platform for solid-state quantum computers.
Researchers have investigated the performance capability of unmanned aerial vehicles (UAVs) as a communication platform with autonomous underwater vehicles (AUVs) for ocean and seafloor monitoring research. Studies suggest that UAVs exhibit suitable communication performance for underwater measurement up to approximately 1 km from the shore, owing to their operation speed, robust hovering control,
In this article, we advance divide-and-conquer strategies for solving the community detection problem in networks. We propose two algorithms that perform clustering on several small subgraphs and finally patch the results into a single clustering. The main advantage of these algorithms is that they significantly bring down the computational cost…
The p53 tumor suppressor protein, known to be critically important in several processes including cell-cycle arrest and apoptosis, is highly regulated by multiple mechanisms, most certifiably the Murine Double Minute 2–Murine Double Minute X (MDM2–MDMX) heterodimer. The role of MDM2–MDMX in cell-cycle regulation through inhibition of p53 has been well…
Accurate characterization of the time courses of blood-oxygen-level–dependent (BOLD) signal changes is crucial for the analysis and interpretation of functional MRI data. While several studies have shown that white matter (WM) exhibits distinct BOLD responses evoked by tasks, there have been no comprehensive investigations into the time courses of spontaneous…
Yersinia pestis causes human plague and colonizes both a mammalian host and a flea vector during its transmission cycle. A key barrier to bacterial infection is the host's ability to actively sequester key biometals (e.g., iron, zinc, and manganese) required for bacterial growth. This is referred to as nutritional immunity….
SARS-CoV-2 spillback from humans into domestic and wild animals has been well documented, and an accumulating number of studies illustrate that human-to-animal transmission is widespread in cats, mink, deer, and other species. Experimental inoculations of cats, mink, and ferrets have perpetuated transmission cycles. We sequenced full genomes of Vero cell–expanded…
Bacterial cell wall peptidoglycan is essential, maintaining both cellular integrity and morphology, in the face of internal turgor pressure. Peptidoglycan synthesis is important, as it is targeted by cell wall antibiotics, including methicillin and vancomycin. Here, we have used the major human pathogen Staphylococcus aureus to elucidate both the cell…
Mammalian sperm migration within the complex and dynamic environment of the female reproductive tract toward the fertilization site requires navigational mechanisms, through which sperm respond to the tract environment and maintain the appropriate swimming behavior. In the oviduct (fallopian tube), sperm undergo a process called "hyperactivation," which involves switching from…
Fevers are considered an adaptive response by the host to infection. For gregarious animals, however, fever and the associated sickness behaviors may signal a temporary loss of capacity, offering other group members competitive opportunities. We implanted wild vervet monkeys (Chlorocebus pygerythrus) with miniature data loggers to obtain continuous measurements of…
The rapid development of nanotechnology has greatly benefited modern science and engineering and also led to an increased environmental exposure to nanoparticles (NPs). While recent research has established a correlation between the exposure of NPs and cardiovascular diseases, the intrinsic mechanisms of such a connection remain unclear. Inhaled NPs can…
The human ERG (hERG) K+ channel has a crucial function in cardiac repolarization, and mutations or channel block can give rise to long QT syndrome and catastrophic ventricular arrhythmias. The cytosolic assembly formed by the Per-Arnt-Sim (PAS) and cyclic nucleotide binding homology (CNBh) domains is the defining structural feature of…
Cells cooperate as groups to achieve structure and function at the tissue level, during which specific material characteristics emerge. Analogous to phase transitions in classical physics, transformations in the material characteristics of multicellular assemblies are essential for a variety of vital processes including morphogenesis, wound healing, and cancer. In this…
Mentalizing, the ability to infer the mental states of others, is a cornerstone of adaptive social intelligence. While functional brain mapping of human mentalizing has progressed considerably, its evolutionary signature in nonhuman primates remains debated. The discovery that the middle part of the macaque superior temporal sulcus (mid-STS) region has…
Plants and animals use cell surface receptors to sense and interpret environmental signals. In legume symbiosis with nitrogen-fixing bacteria, the specific recognition of bacterial lipochitooligosaccharide (LCO) signals by single-pass transmembrane receptor kinases determines compatibility. Here, we determine the structural basis for LCO perception from the crystal structures of two lysin…
Actions with identical goals can be executed in different ways (gentle, rude, vigorous, etc.), which D. N. Stern called vitality forms [D. N. Stern, Forms of Vitality Exploring Dynamic Experience in Psychology, Arts, Psychotherapy, and Development (2010)]. Vitality forms express the agent's attitudes toward others. In a series of fMRI…
Many intrinsically disordered proteins (IDPs) may undergo liquid–liquid phase separation (LLPS) and participate in the formation of membraneless organelles in the cell, thereby contributing to the regulation and compartmentalization of intracellular biochemical reactions. The phase behavior of IDPs is sequence dependent, and its investigation through molecular simulations requires protein models..
Electrolyte-gated transistors (EGTs) hold great promise for next-generation printed logic circuitry, biocompatible integrated sensors, and neuromorphic devices. However, EGT-based complementary circuits with high voltage gain and ultralow driving voltage (<0.5 V) are currently unrealized, because achieving balanced electrical output for both the p- and n-type EGT components has not been…
The anterior end of the mammalian face is characteristically composed of a semimotile nose, not the upper jaw as in other tetrapods. Thus, the therian nose is covered ventrolaterally by the "premaxilla," and the osteocranium possesses only a single nasal aperture because of the absence of medial bony elements. This…
Gram-negative bacteria are surrounded by a protective outer membrane (OM) with phospholipids in its inner leaflet and lipopolysaccharides (LPS) in its outer leaflet. The OM is also populated with many β-barrel outer-membrane proteins (OMPs), some of which have been shown to cluster into supramolecular assemblies. However, it remains unknown how…
If you're working from a home office or, well, an office-office, a printer is still a must-buy gadget. While 3D printers offer more creative possibility, all-in-one printers are a great blend of form and functionality, as a printer, scanner, copier, and sometimes a fax into one device. All-in-one printers are typically either use inkjet or laser technology, with the addition of a copier/scanner o
Researchers used transcriptomics (a type of gene sequencing) calibrated using information from the fossil record to create the first phylogenetic reconstruction of the insect order Odonata (dragonflies and damselflies), covering 105 species. This reconstruction of the evolutionary history allowed robust estimations of the species divergence time (or first appearance, around 200 million years ago)
Researchers take advantage of quantum entanglement to generate an incredibly large bandwidth using a thin-film nanophotonic device that could lead to advances in metrology, sensing and quantum networks for information processing and communications.
A study finds that changing the biochemistry of parts of brain cells abolished the formation of amyloid beta plaques in a mouse model of Alzheimer's disease. The finding might eventually lead to treatments that prevent the memory-robbing condition in humans.
Scientists suggest that reliance on modern irrigation technologies as a water-use efficiency strategy is a 'zombie idea' — one that persists no matter how much evidence is thrown against it. Technology adoption as a water-saving method for improving irrigation efficiency is ineffective, and can actually worsen water scarcity, according to researchers.
Consumer sentiment has remained virtually unchanged in the past three months, at levels comparable to the pandemic low point in April 2020, according to the University of Michigan Surveys of Consumers.
The majority of Texans support, at varying intensities, the newly enacted state laws aimed at reshaping elections in the state, according to a new five-year survey project from the University of Houston Hobby School of Public Affairs and Texas Southern University Jordan-Leland School of Public Affairs.
The World Bank's flagship report, The Changing Wealth of Nations/ for the first time emphasizes the importance of social capital to sustainability. By including the role of trust, social norms and community cohesiveness in securing a sustainable future, it represents a major advance in the international effort to go beyond GDP for the measurement of progress.
Weeks after a massive oil spill marred the Orange County coast with significant environmental and economic damage, state lawmakers met in Sacramento on Thursday to demand that those responsible "be held accountable," with one legislator calling for an end to offshore drilling in California.
We live in times when technology has become a regular part of our lives. Besides many portable devices, smartphones or wrist-worn fitness trackers are equipped with sensors to measure health parameters like pulse or blood saturation with oxygen. The appearance of such devices on the market made our lives easier. It revolutionized medicine, enabling us to check even the glucose level at home.
A decade ago, genome sequencing revealed a big surprise: about 50 percent of human cancers are linked to mutations in what are known as epigenetic regulators, which control the activity of genes. Medical researchers have now developed a new drug-like molecule that can counteract the effects of mutated epigenetic regulators, which are known to drive certain types of cancer including lymphoma.
Right-wing backlash against National Institute of Allergy and Infectious Diseases head Anthony Fauci intensified this week over an unexpected issue: beagle puppies. The dispute was sparked last Friday by a letter to Fauci from a bipartisan group of legislators, who criticized NIAID for using dogs in research.
Experts have identified the way to tune the strength and ductility of a class of materials called high-entropy alloys. The discovery may help power-generation and aviation industry develop more efficient engines.
A forgotten antibiotic, temocillin, led to lower selection of resistant bacteria than the standard treatment for febrile urinary tract infection. Thus, temocillin may be useful in treating severe urinary tract infections that give rise to fever, and contribute to a reduced spread of resistant bacteria in hospitals.
Researchers uncovered key networks that simultaneously control pluripotency and readiness for cell death (apoptosis), helping to ensure optimal conditions for embryonic development. The study's findings offer new insights into cancer genetics and a novel approach for regenerative medicine research.
Cerebral palsy (CP) affects around two out of every 1000 children born worldwide. Physical therapy is the foremost way of improving movement, balance, and posture in children with CP. Research has shown that hippotherapy, a form of physical therapy involving horse riding, is effective for treating CP. But how exactly does it help? In a recent study, researchers explore this question and provide in
For the first time, researchers at D-BAUG have measured air-water flows with velocities exceeding 40 m/s. To this end, two challenging measurement campaigns were carried out in the tunnel spillway of a 225 m high dam, for which special probes first had to be developed. With the new data, existing design guidelines can be validated, and so-called scale effects can be assessed more accurately. This
Astrobiology is a scientific field that studies the origin,evolution, and distribution of life and habitability in the universe. Mars is the most promising planet for the discovery of extraterrestrial life in the solar system; thus, exploration of Martian life and habitable environment have been a special focus in planetary science.
The light-matter interaction has long been one of the most advanced areas in physics. Recently, it has attracted more attentions due to the rapid development of ultra-short lasers, and a variety of ultra-fast phenomena have been experimentally achieved, including band structure, transition dipole moments, and Berry curvature.
A multi-institution team of researchers has discovered a genetic signature that can identify drivers of poor outcomes in advanced estrogen-receptor positive (ER+) breast cancer, which could one day lead to personalized treatment for patients.
Scientists used to think that only mammals sought out truffles, but a new study shows that birds also pursue these underground fungi. The researchers collected the feces of two common ground-dwelling bird species in Patagonia and found they contained truffle DNA and viable truffle spores. The spread of truffles is important to the health of forest ecosystems, where truffle species and other mycorr
Developing below the soil surface, desert truffles are hard to find. Recently, researchers updated the number of known species of the desert truffle genus Terfezia occurring in Portugal from three to ten species. They thoroughly characterized their ecological preferences, adding new knowledge on Terfezia's cryptic lifestyle. These findings are of major importance, as desert truffles have a high ec
Scientists used a drone and a multi-agent computerized system for complex social structure modeling to test, for example, whether individuals in a herd of feral horses synchronize according to their social network. For this hypothesis, two sub-models were created, one of which only takes into an account the same unit group members. The other sub-model applies to the entire herd. The simulation and
Climate action can be a vehicle to deliver dignity, opportunity and equality for all. UN Deputy Secretary-General Amina J. Mohammed invites us to reimagine what the journey to net-zero could look like if we invest in people's climate efforts while prioritizing the 17 Sustainable Development Goals — a blueprint of interlinked global goals to protect humanity and our warming planet. "It's time to m
mRNA vaccines are groundbreaking—but the mRNA inside them is fragile. Kathryn Whitehead explains how scientists have created the right "packing material" to safely deliver these to the right cells. (Image credit: Bret Hartman/Bret Hartman / TED )
An entomologist at the University of Kentucky has found that requiring peer review reviewers to sign their names to their review comments could bias their results. In his paper published in Proceedings of the Royal Society B: Biological Sciences, Charles Fox, describe how he studied peer-reviewed articles for one prominent journal and what he learned about the process.
New research from Edith Cowan University (ECU) has identified some key causes of workplace fatalities in the Western Australian mining and resources sector, which could assist companies to reduce the number of workers injured on the job.
Starting around 3,000 years ago, a wave of innovation began to sweep through human societies around the globe. For the next millennium the continued emergence of new technologies had a dramatic effect on the course of human history.
Soft matter can be found in many everyday materials, such as food, cosmetics, and the cells in our own bodies. The structure of these tiny, soft materials is determined by various interactions, one of which is electrostatic interaction. For his Ph.D. research, Christian Sproncken used electrostatic interactions to assemble soft materials into various structures consisting of charged polymer chains
This November, world leaders will meet once again to negotiate and discuss measures to address the global climate crisis. The question is, will COP26 in Glasgow make any difference? A recently published research article identifies key reasons behind the world's 30-year record of failure to bring down global emissions.
Rivers flowing from the Tibetan Plateau and the surrounding high Asian mountains which support one-third of the world's population have experienced rapid increases in annual water and sediment runoff since the 1990s, and the volume of sediment washed downstream could more than double by 2050 under the worst-case scenario, a team of scientists has found.
Visible light is extremely important in nature. Seen by the human eye, it is the most intense light emitted by the sun to reach the earth's surface and is an essential element for fundamental biological processes underlying life. However, it is difficult to generate coherent visible light, like the light of a laser, that is intense for a short amount of time, in the order of the femtosecond.
In rural areas, basic health care can be out of reach. Keller Rinaudo founded Zipline, a delivery company that uses drones to deliver necessary medical supplies within hours, even minutes. (Image credit: Ryan Lash/Ryan Lash / TED)
Astrophysicist Erika Hamden spent 10 years building FIREBall, a telescope that reaches the stratosphere and looks for clues to how stars form. Launching it was more challenging than she ever imagined. (Image credit: Ryan Lash/Ryan Lash / TED)
Using Resonant Magnetic Perturbations (RMP), researchers led by Prof. Sun Youwen from the Institute of Plasma Physics of the Chinese Academy of Sciences took the lead in demonstrating the integrated Edge Localized Mode (ELM) and divertor power flux control in target plasmas with parameters close to International Thermonuclear Experimental Reactor (ITER) high fusion gain (Q) operation.
Improved air quality in cities resulting from cutting carbon emissions could lead to large reductions in childhood asthma cases, premature births and incidences of babies born at an unhealthily low weight, according to a study carried out by researchers at the London School of Hygiene & Tropical Medicine (LSHTM).
Stream Expedition Unknown on discovery+ ► https://www.discoveryplus.com/show/expedition-unknown #Discovery #ExpeditionUnknown #DBCooper Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Follow Us on TikTok: https://www.tiktok.com/@Discovery We're on Instagram! https://instagram.com/Discovery Join Us on Facebook: https://www.facebook.com/Discovery Follow Us on Twitter: https://twitter.com/D
En stark maskulinitet där vapen och våld romantiseras är vanligt i kriminella gäng. Men ofta är denna machokultur en kompensation för ett tidigt utanförskap. Att jobba med manlig identitet kan vara en del av lösningen. Bilderna är medvetet förnedrande. Den unge mannen sitter på golvet i en lägenhet påtvingad typiska "kvinnokläder". Det var i april 2020 som rapparen Nils Grönberg, med artistnamnet
While lockdowns in the early days of the COVID-19 pandemic were challenging for teen girls' mental health, they also offered a respite from their packed everyday lives. That's a warning sign for how stressful the lives of teens have become, researchers say. Even before the pandemic, experts sounded the alarm about teen mental health. "Over the last decade, we've been seeing these really skyrocket
Less is more when it comes to just how many subterranean termites have to eat a chemical known as a chitin synthesis inhibitor before the entire colony is eliminated, a study of 1.68 million termites shows. For the study, which appears in the Journal of Pest Science , researchers took a closer look at how much bait it takes to eliminate a subterranean colony. As a prominent industry standard used
Facebook's current Oculus headsets clock in at much lower prices than the headsets of yesteryear, and yet they're still impressive pieces of hardware. However, the social media giant is working on a headset that isn't going to compete on price. The company teased the upcoming Project Cambria VR headset at the Connect conference, saying it will be a high-end experience rather than a replacement fo
Combining electroencephalogram data with clinical observations can help doctors to better determine if generalized epilepsy patients will respond to treatment, according to a new study. For the study researchers used a new statistical model that is 80% accurate in distinguishing between drug-resistant and drug-responsive generalized epilepsy. "Traditionally, we had few tools available to help us
From Mercury to the depths of the distant Kuiper Belt, there aren't many unexplored corners of the solar system out there. One class of object, however, remains to be visited: the transitional Centaurs out beyond the orbit of Jupiter. Now, a new study from the University of Chicago recently accepted in The Planetary Science Journal looks at the feasibility of sending a mission by mid-century to in
Forest area is increasing in Europe, mainly because farms are getting fewer and smaller. This should be good news, but it must be put into perspective alongside the loss of forest that the EU's growing agricultural imports cause in third countries. We call this "imported deforestation."
Framing is important, and often exists below our conscious awareness. If we are not even aware that we are framing an issue in a certain way, and that other framings are possible, this will influence our thinking in ways that we cannot anticipate or correct for. Sometimes a particular framing is deliberate, a strategy for propaganda and rhetorical advantage. This is often done in order to win a d
In the first study of horse falls in over 20 years, University of Bristol academics have identified some simple interventions to reduce the risk of injury in equestrian sport—making it safer for both horses and riders.
When record-breaking wildfires in western Russia killed 65 people, injured 1,068, destroyed 3,500 homes and caused billions in damages in 2010, it was no longer business-as-usual in Russia's response to the impacts of climate change.
In a caring, symbiotic relationship, mycorrhizal fungi live and feed in the roots of specific plants, while providing water and nutrients to their "companion." In arid and semi-arid environments, mycorrhization processes are essential to the survival of both plants and fungi. Moreover, the fungus' hyphal network, which spreads within the soil connecting several plant individuals, is of utmost impo
Eran Amichai, a postdoctoral fellow in ecology, evolution, environment and society, studies how echolocation signals differ within a population of big brown bats. Amichai records echolocation signals to identify specific bats, and then films the individuals in a large chamber with open and wooded areas to see whether the unique sensory signals are optimized for open or wooded environments.
Researchers from Daegu Gyeongbuk Institute of Science and Technology investigate the impact of high concentration electrolyte (HCE) dilution on lithium metal battery (LMB) cycling over a wide temperature. Their comprehensive study reveals that dilution of HCE significantly improves Li+ ion transport at lower temperatures and thermal stability of solid-electrolyte interface at higher temperatures,
An analysis of almost 30,000 different wines shows that wine judges give higher scores to wines made with less well-known varieties of grape. Details of the study are reported in the International Journal of Entrepreneurship and Small Business.
By leveraging a popular weather forecasting model, environmental engineers at Duke University have demonstrated that sharp contrasts in relatively small land features play an outsized role in local weather developments, which can in turn influence larger climate trends. The study indicates that the addition of such detailed data, which is currently overlooked in climate and weather forecast models
The ability to quickly google the answer to just about any question changes how people perceive their own intelligence, research finds. People lose sight of where their memory ends and where the internet begins, the findings indicate. "When we're constantly connected to knowledge, the boundaries between internal and external knowledge begin to blur and fade," says Adrian Ward, assistant professor
PLUS. Den verdenskendte 3D-tegning af coronavirus har ifølge spanske forskere en 'lav didaktisk værdi', og den udbredte brug i medierne under pandemien kan have påvirket befolkningens adfærd i den forkerte retning.
Er tiden blot en illusion, eller er den en realitet i sig selv? Var blockchain bare en hype? Og spænder planen om energiøer i virkeligheden ben for udbygning af vindkraften? Lyt med i ugens Transformator.
A pediatrics journal has issued an expression of concern for a 2007 paper by a group of Canadian researchers whose leader, Gideon Koren, resigned in 2015 under a cloud after concerns surfaced about the integrity of the data in hundreds of his published studies. Koren, once a prominent pediatrician and pharmacologist at the University of … Continue reading
Kulturminister Ane Halsboe-Jørgensen er overrasket over whistleblower Frances Haugens seneste afsløringer af, at Facebook tilsyneladende har ignoreret viden om, at virksomhedens platforme har skadelige effekter. Nu ser hun det som sin vigtigste opgave at gribe ind.
Ett bortglömt antibiotikum, temocillin, gav färre resistenta tarmbakterier jämfört med standardbehandling mot urinvägsinfektion med feber. Temocillin kan vara ett bra alternativ för behandling vid svår urinvägsinfektion och bidra till minskad spridning av resistenta bakterier på sjukhus. Den kliniska effekten var lika bra för temocillin som för standardbehandlingen med cefotaxim, och även biverkn
Epidemihospitalet Filadelfia står over for et formandsskifte. Kjeld Møller Pedersen takker, efter 20 år som bestyrelsesmedlem og 14 år som bestyrelsesformand, af og giver stafetten videre. Afløseren er fundet indenfor hospitalets egne rækker.
Nature Communications, Published online: 29 October 2021; doi:10.1038/s41467-021-26481-8 Metal electrode interfaces and interphases are critical for the development of future high-energy metal batteries. Here, Dr Jelena Popovic-Neuber discusses the state of the art, issues and strategies to improve the stability of metal electrodes toward practical battery systems.
Nature Communications, Published online: 29 October 2021; doi:10.1038/s41467-021-26522-2 Weak value amplification in a compact format can lead to improved measurement capabilities in practical applications. Here the authors demonstrate weak value amplification in an integrated photonic chip with a multimode interferometer.
Nature Communications, Published online: 29 October 2021; doi:10.1038/s41467-021-26478-3 It remains challenging to integrate topological insulators (TI) with magnetic tunnel junctions (MTJ) for spintronics applications. Here, the authors achieve a large tunneling magnetoresistance ratio and a low switching current density in a TI-MTJ device at room temperature, very promising for TI-driven magnet
Nature Communications, Published online: 29 October 2021; doi:10.1038/s41467-021-26368-8 In this manuscript, Negri, Zheng, Casado et al develop a stable and flexible diradical. Using a combination of experimental and theoretical techniques, they show how heating leads to change in the electronic and spin delocalizations ocurring between quinoidal and aromatic forms, and elucidate a unique spin-vi
Nature Communications, Published online: 29 October 2021; doi:10.1038/s41467-021-26519-x Whether microglial activation constitutes a primary pathological event in synucleinopathies is not known. Here, the authors generated a mouse model over-expressing α-synuclein in microglial cells and found these mice developed progressive dopaminergic neuron degeneration and microglia developed a reactive, pr
Nature Communications, Published online: 29 October 2021; doi:10.1038/s41467-021-26489-0 Biomarkers of prostate cancer metastasis have been difficult to determine with confidence. Here the authors analyse mutation prevalence in 1844 prostate cancers and show that ZNRF3 loss is enriched in metastatic, castration-resistant prostate cancer and associated with metastasis of localized disease.
Nature Communications, Published online: 29 October 2021; doi:10.1038/s41467-021-26425-2 High-entropy alloys (HEAs) have attracted increasing attention in diverse field. Here, the authors report PtRuNiCoFeMo HEA with enhanced activity, stability and preferable CO anti-poisoning in alkaline hydrogen oxidation reaction.
Shanghai scientist Zhang Yongzhen faced an agonizing decision after his team mapped the genome of a mysterious new coronavirus from Wuhan. Each day the genetic information wasn't publicly available meant another day before tests for the infection could be developed, potentially jeopardizing global health.
Three hundred scientists from 255 institutions in 46 countries, including Professor Dirk Zeller and Ph.D. candidate Lincoln Hood from The University of Western Australia, are asking members of the World Trade Organization (WTO) to ban harmful fisheries subsidies at the 12th Ministerial Conference to be held in Geneva, Switzerland next month.
Elizabeth Azzuz stood in prayer on a Northern California mountainside, arms outstretched, grasping a handmade torch of dried wormwood branches, the fuel her Native American ancestors used for generations to burn underbrush in thick forest.
Brazil's greenhouse gas emissions rose by 9.5 percent last year, mostly because of deforestation, a report said Thursday, making it one of the only major economies not to cut pollution as the pandemic hit.
Når personer med lungesygdomme træner i og omkring eget hjem, har det en positiv effekt, viser statusartikel. Reservelæge håber, at hjemmetræning kan være et tilbud til dem, der ikke er interesseret eller er forhindret i at deltage i strukturel rehabilitering.
Det har været mere end ti år undervejs, men nu står den fysiske fremtid for retspsykiatrien i Roskilde klar, og i løbet af november flytter patienter fra det gamle Sct. Hans og Glostrup retspsykiatri ind i nybyggede omgivelser. Nybyggeriet skal blandt andet give bedre mulighed for rehabilitering og for at have en meningsfyldt hverdag under opholdet. Håbet er, at det betyder hurtigere bedring og k
Inför klimatmötet COP26 i Glasgow som börjar på söndag ger Kungliga Vetenskapsakademien ut en enkel sammanfattning av läget, som är "allvarligt men inte kört". Sju klimatforskare förmedlar forskarsamhällets samlade kunskap på 15 sidor.
A lot of people, even some experts, are making assumptions about so-called "TikTok tics" that might be inaccurate or even harmful for young people with Tourette syndrome. The post first appeared on Science-Based Medicine .
Aalborg Universitetshospital har gode resultater med hjemmebehandling til patienter, der lider af lungesygdommen Alfa-1-antitrypsin-mangel. Målet er, at patienterne kan leve et så normalt liv som muligt trods sygdommen.
Schneider Shorts 29.10.2021 – fluvoxamine officially a COVID-19 game-changer, lab leak still just a conspiracy theory, Retraction Watchdogs catch a cheating student, papermill customers get sanctioned, and lawsuits everywhere: Sabatini sues Whitehead, Macchiarini trial begins in Sweden, Athira Pharma separates from cheating CEO while facing investor lawsuits, and Raoult finally facing criminal cha
LEDER: Det er oplagt at spørge, hvor solidariteten er henne hos alle dem, der hylder glansbilledet af familielægen? Solidariteten med patienterne og med de læger, der skal dække de mindre attraktive områder?
KRONIK: Visionen er klar: Fremtidens sundhedsvæsen skal være nært, og den praktiserende læge skal spille en central rolle. Den aktuelle problematik om praktiserende lægers manglende adgang til diagnostiske undersøgelser til patienter med vage symptomer på kræft eller alvorlig sygdom viser imidlertid, at der er langt fra vision til virkelighed.
DEBAT: Det går ikke godt nok på demensområdet. Hverken i forhold til opsporing, diagnosticering eller behandling. Så hvad sker der, når der i fremtiden kommer 50 pct. flere patienter med en demenssygdom? Der er behov for en ny handlingsplan for demens, så vi sammen kan håndtere udfordringerne, skriver de to adm. direktører for hhv. Roche Pharmaceuticals i Danmark og Biogen i et fælles debatindlæg.
Nature, Published online: 29 October 2021; doi:10.1038/d41586-021-02978-6 An international team of researchers wants to find people who are genetically resistant to SARS-CoV-2, in the hope of developing new drugs and treatments.
Carbon occurs on the Earth in a variety of structures and forms. Elemental Carbon is usually formed under conditions of high pressure and temperature. Researchers have now, for the first time, identified microorganisms that produce elemental carbon.
Even low levels of physical therapy were associated with lower risk of chronic opioid use after total knee replacement. The team's analysis of over 67,000 patient records revealed that the longer a patient waits to start physical therapy, the greater the eventual odds of chronic opioid use.
Engineers have developed smart material technology that, with the flip of a switch, can alternate between harvesting heat from sunlight and allowing an object to cool. The window-like device has no moving parts and could be a boon for HVAC savings, potentially cutting energy usage by nearly 20% in the United States alone.
Nature, Published online: 29 October 2021; doi:10.1038/d41586-021-02976-8 Poll shows that researchers of Chinese descent worry about surveillance by the US government and have stepped back from collaborations in China.
Cracked phone screens could become a thing of the past thanks to breakthrough research The researchers have unlocked the technology to produce next-generation composite glass for lighting LEDs and smartphone, television and computer screens. The findings will enable the manufacture of glass screens that are not only unbreakable but also deliver crystal clear image quality.
Scientists discover the genetics inside legumes that control the production of an oxygen-carrying molecule, crucial to the plant's close relationships with nitrogen-fixing bacteria. The finding offers the potential to give other plants the ability to produce ammonia from bacteria — reducing the need for the fossil fuel-dependent and polluting practice of applying synthetic fertiliser to crops.
Deep in an Indiana forest, a team of scientists skulked atop hillsides after dark. Carrying radios and antennas, they fanned out, positioning themselves on opposite ridges to wait and listen. Their quarry? Endangered Indiana bats and threatened northern long-eared bats.
An international, interdisciplinary research team is using satellite images to measure the changes of coastal wetlands in China from the early 1980s to the present. The research team is also assessing the effects of conservation efforts on preserving and recovering these important ecosystems.
A new study shows how changes in light conditions have a significant influence on the growth and impact of harmful algae blooms. The bottom line: a warming climate looks good for the growth of toxic algae and may disrupt other organisms that are part of the food web — whether they graze on this algae or are consumed by it.
In the traditional narrative of the evolving 21st century workplace, technological substitution of human employees is treated as a serious concern, while technological complementarity — the use of automation and artificial intelligence to complement workers — is viewed as a good thing. But a new study tells a more nuanced story, demonstrating that the integration of automation and AI in the work
NASA Jet Propulsion Lab system architect Casey Handmer is impressed with SpaceX's progress toward developing a rocket capable of sending astronauts to the Moon and even Mars. "Two years ago Starship was a design concept and a mock up," Handmer wrote in a lengthy post on his personal blog about the hyper-ambitious rocket. "Today it's a 95 percent complete prototype that will soon fly to space and
NASA's Perseverance rover is the most advanced machine ever sent to the red planet with a boatload of cameras and a refined design that should stand the test of time. Still, it's just a robot, and sometimes human intuition can help a robot smarten up. If you're interested in helping out, NASA is calling on any interested humans to contribute to the machine learning algorithms that help Perseveran
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