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Nyheder2022juli02

Many dissimilar NusG protein domains switch between α-helix and β-sheet folds
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31532-9 Folded proteins are composed of secondary structures, α-helices and β-sheets, that are generally assumed to be stable. Here, the authors combine computational prediction with experimental validation to show that many sequence-diverse NusG protein domains switch completely from α-helix to β-sheet folds.
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New sibling diagnosis for post-traumatic stress disorder
The World Health Organization (WHO) recently listed a new sibling diagnosis for post-traumatic stress disorder (PTSD), termed complex post-traumatic stress disorder (CPTSD). An international team has now summarized the symptoms of the long-awaited new diagnosis and issued guidelines for clinical assessment and treatment.
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LATEST

Elon Musk Takes Flabbergastingly Awkwardly Picture With the Pope
Papal Pose Never has a photo looked as awkward as the one Tesla CEO Elon Musk and his children just took with the Pope. The billionaire tweeted the group pic yesterday — breaking a prolonged absence from the site — which shows four of his kids standing next to Pope Francis while the would-be Twitter head stood off to the left. There were almost certainly rules about distancing and not touching th
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Terrifying Video Shows Self-Driving Tesla Head Into Oncoming Traffic
Wrong Way Tesla's rollout of its controversial "Full Self-Driving" (FSD) beta has challenged, to say the least. Countless videos have shown Tesla vehicles breaking traffic laws , veering into the wrong lane, getting dangerously close to pedestrians, and making the wrong turns. In the latest video , which dates back to May but only started making the rounds this week , Galileo Russell from the You
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UK scientists warn of urgent need for action on vaccines to head off autumn Covid wave
Expert fear that new variants will emerge and stress the need to prepare the best drugs to combat it Health authorities need to act urgently to prepare for an autumn that could see further waves of Covid-19 cases spreading across the UK. That is the clear warning from scientists and doctors after last week's figures revealed another dramatic jump in cases. More than 2 million people across Britai
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FBI Offers Huge Reward for "Cryptoqueen" Accused of Stealing $4 Billion
On the Run The second-most wanted person in the US right now is a Ponzi scheme legend known as the Cryptoqueen. The FBI added Ruja Ignatova's name to its ten most-wanted list on Thursday and said she's probably traveling with armed guards and may have even gotten plastic surgery as a disguise. They're offering up to $100,000 in cold hard cash for information leading to her arrest. Yesterday, the
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Robots Now Delivering VR Porn Headsets to the Terminally Lonely
Special Delivery What happens in VR in Vegas, amirite? Forget strap ons — a porn outfit called VR Bangers is helping customers strap into a brand new porn experience in Sin City. For the curious and/or terminally lonely, the adult entertainment outfit says it's delivering smut-enabled VR headsets via delivery robots. Although the city's notorious getaways often offer adult movies for customers to
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North Korea Claims It Only Got COVID Because South Korea Sent Over "Tainted Balloons"
North Korea has finally decided to give its residents the true story behind COVID-19 — or at least a fairy tale version that dictator Kim Jong Un decided would most advantageous for his brutal regime . State run newspaper Pyongyang Times made the bizarre claim earlier today that tainted balloons, sent from neighboring South Korea, landed on North Korean territory and infected children who then sp
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Sorry Folks, That Photo of Doom Running on a McDonald's Kiosk Is Fake
McFaker A few Doom fans spotted something wrong with a viral photo that supposedly showed the 1993 classic running on a McDonald's ordering kiosk. Bad news, folks: turns out it's almost certainly a fake. The saga started with a Thursday tweet in which a pseudonymous user posted a shot of an apparently hacked touchscreen kiosk at the fast food chain. The user claimed somebody had installed Doom us
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Disturbing Discovery Finds That Space Does Something Bad to Astronauts' Bones
An alarming new study has found that spending months in space can result in the equivalent of two decades worth of bone loss for astronauts. The study, published in Scientific Reports , details how researchers at Canada's University of Calgary made their troubling discovery — and explains a potential fix for an issue that could become much more widespread as more and more civilians begin travelin
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Photo-tailored heterocrystalline covalent organic framework membranes for organics separation
Nature Communications, Published online: 02 July 2022; doi:10.1038/s41467-022-31361-w Covalent organic frameworks (COF) hold great promise in filtration and separation but combining facile processing, high crystallinity and high separation performance remains challenging. Here, the authors demonstrate that heterocrystalline COF membranes in which high-crystalline regions are tightly linked by low
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Electroredox carbene organocatalysis with iodide as promoter
Nature Communications, Published online: 02 July 2022; doi:10.1038/s41467-022-31453-7 Oxidative carbene organocatalysis has been developed as a versatile synthetic method, but has been paired with electroredox chemistry in only limited examples. Herein, enantioenriched heterocycles are synthesized from racemic substrates via an iodide-promoted NHC organocatalysis system that is powered by electro
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The megabase-scale crossover landscape is largely independent of sequence divergence
Nature Communications, Published online: 02 July 2022; doi:10.1038/s41467-022-31509-8 The frequency of recombination varies along chromosomes and highly correlates with sequence divergence. Here, the authors show that polymorphisms are not a major determinant of the megabase-scale recombination landscape in Arabidopsis, which is rather determined by chromatin accessibility and DNA methylation.
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Scientists Discover Horrifying Crab That's Covered in "Hair"
Crab Drip Behold l amarckdromia beagle , a recently discovered sponge crab with a fluffy coat that bridges the gap between "adorable" and "horrifying." Sponge crabs — named for their creative habit of turning sea sponges into protective outerwear — have been known to the scientific community for some time now. But while most of these Australian crustaceans keep their designs pretty minimal, this
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A stitch in time: the benefits of teaching prisoners to sew
Learning a craft can change lives – and a scheme showing inmates how to use a needle and thread has had some remarkable results It's a balmy afternoon in southwest London and there's a deafening sound overhead. My companion, Sebastian, jumps excitedly to his feet and leaps outside into the sun-dappled courtyard. Cupping one hand over his eyes, he points the other towards a luxury Pullman train cl
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US Hypersonic Missile Test Fails For A Second Time
Closing Time The United States continues to fall behind Russia and China when it comes to hypersonic missiles after a second test of the high tech weapon failed. The Department of Defense, per statements to Bloomberg , confirmed that US hypersonic weapons tests this week sent from Hawaii had failed, though it didn't provide many details beyond that. "An anomaly occurred following ignition of the
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Great auks and seal-headed men: a window into ice age Provence
The Cosquer cave near Marseille astonished the diver who discovered it with its ancient depictions of sea and land animals. Now it has been painstakingly recreated in the French port for all to enjoy It was in 1985 that the diver Henri Cosquer discovered, along the coast from Marseille, what has been called an "underwater Lascaux" after the famous cave network in the Dordogne. After several faile
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Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains
Nature Communications, Published online: 02 July 2022; doi:10.1038/s41467-022-31615-7 SARS-CoV-2 variants of concern are less susceptible to therapeutic neutralizing antibodies, given mutations in the surface glycoprotein S. Here, Case et al. show that therapeutic antibodies S309 and AZD7442 reduce lung infection with SARSCoV-2 Omicron lineages in humanized mouse model despite the loss of neutral
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Weekend reads: Retracted COVID-19 papers keep being cited; "'difficult' name penalty"; economist accused of plagiarism
ould you consider a donation to support Weekend Reads, and our daily work? Thanks in advance. The week at Retraction Watch featured: The Lancet more than doubles its impact factor, eclipsing NEJM for the first time ever Author demands a refund after his paper is retracted for plagiarism Seven months after an author request, journal retracts February: … Continue reading
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Freddy Has His Hands Full with an Amateur Mine | Gold Rush: Freddy Dodge's Mine Rescue
Stream Gold Rush: Freddy Dodge's Mine Rescue on discovery+ ▶︎ https://www.discoveryplus.com/show/gold-rush-freddy-dodges-mine-rescue #GoldRush #discovery #MineRescue Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Follow Us on TikTok: https://www.tiktok.com/@Discovery We're on Instagram! https://instagram.com/Discovery Join Us on Facebook: https://www.facebook.com/Discovery Follow Us on
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This Week's Awesome Tech Stories From Around the Web (Through July 2)
ARTIFICIAL INTELLIGENCE We Asked GPT-3 to Write an Academic Paper About Itself—Then We Tried to Get It Published Almira Osmanovic Thunström | Scientific American "On a rainy afternoon earlier this year, I logged in to my OpenAI account and typed a simple instruction for the company's artificial intelligence algorithm, GPT-3: Write an academic thesis in 500 words about GPT-3 and add scientific ref
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Anti-dissolution Pt single site with Pt(OH)(O3)/Co(P) coordination for efficient alkaline water splitting electrolyzer
Nature Communications, Published online: 02 July 2022; doi:10.1038/s41467-022-31406-0 Platinum is the most active catalyst for cathodic hydrogen evolution, however it is inefficient for anodic oxygen evolution. Here, authors examine Pt single sites in cobalt hydrogen phosphate as oxygen evolution catalysts in water splitting electrolyzers.
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What Lies Behind That 'No Trespass' Sign
I always pined for the wide open, though I grew up in suburban Maryland, hemmed in by private land and no trespass signs. Even as a boy, one with his nose in books, I knew that the East had not always been so parceled into private fiefdoms. In fact, it had once been a place where anyone could roam, more open than the West is today. It was not until years later, though, when researching a scholarl
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The January 6 Committee Is Going to Have the Final Word
During its astonishing Tuesday hearing about Donald Trump's actions on the day of January 6 , the House select committee investigating the insurrection made clear that the integrity of its work is under threat. "The same people who drove the former president's pressure campaign to overturn the election are now trying to cover up the truth about January 6," warned committee chair Bennie Thompson.
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Investigation of the monopole magneto-chemical potential in spin ices using capacitive torque magnetometry
Nature Communications, Published online: 02 July 2022; doi:10.1038/s41467-022-31297-1 Magnetic-field induced phase transitions in spin-ice materials have been investigated with various experimental techniques. Here, the authors demonstrate the capability of capacitive torque magnetometry in probing magnetic interaction energies and establishing magnetic phase boundaries in Ho2Ti2O7.
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Structure induced laminar vortices control anomalous dispersion in porous media
Nature Communications, Published online: 02 July 2022; doi:10.1038/s41467-022-31552-5 Most porous systems comprise structures characterized by dead-end and transmitting pores. Here, authors show that macroscopic transport through such porous medium is controlled by structure-induced laminar vortices inside each dead-end pore, and such cannot be explained by diffusion alone.
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The Accidental Trumpification of NATO
If Donald Trump returns to power in 2025, he will find a world starkly different from the one he tried to construct while president. All hopes of normalizing relations with Russia have been obliterated in the slaughter of Ukraine. China is more powerful than ever. Iran is closer to acquiring nuclear weapons. And Kim Jong Un is still behaving like Kim Jong Un. But, in a narrow yet important sense,
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Platserna att besöka i sommar – forskarna tipsar
Vandra genom Sveriges geologiska historia, eller vårt solsystem. Besök ett nyutgrävt vikingatida båtvarv. Lär dig mer om hur våra lekplatser kom till, eller ta en promenad i Stockholmsskildringarnas spår. Inlägget dök först upp på forskning.se .
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Brinnande våtmarker bidrog till massutdöende
Våtmarker är viktiga kolsänkor för att minska effekterna av vår tids klimatförändring. Under jordens värsta massutdöende för 252 miljoner år sedan, kan uttorkade våtmarker som förstörts av skogsbränder ha utlöst ekosystemens kollaps. Inlägget dök först upp på forskning.se .
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Green gentrification in European and North American cities
Nature Communications, Published online: 02 July 2022; doi:10.1038/s41467-022-31572-1 The relationship between new greenspaces and gentrification is an important one for urbanization. Here the authors show a positive relationship for at least one decade between greening in the 1990s–2000s and gentrification that occurred between 2000–2016 in 17 of 28 studied cities in North America and Europe.
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A convolutional neural network highlights mutations relevant to antimicrobial resistance in Mycobacterium tuberculosis
Nature Communications, Published online: 02 July 2022; doi:10.1038/s41467-022-31236-0 Pathogen whole genome sequencing, coupled with statistical and machine learning models, offers a promising solution to multi-drug resistance diagnosis. Here, the authors present two deep convolutional neural networks that predict the antibiotic resistance phenotypes of M. tuberculosis isolates.
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Researchers use AI to detect new family of genes in gut bacteria
Using artificial intelligence, UT Southwestern researchers have discovered a new family of sensing genes in enteric bacteria that are linked by structure and probably function, but not genetic sequence. The findings, published in PNAS, offer a new way of identifying the role of genes in unrelated species and could lead to new ways to fight intestinal bacterial infections.
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Researchers use AI to detect new family of genes in gut bacteria
Using artificial intelligence, UT Southwestern researchers have discovered a new family of sensing genes in enteric bacteria that are linked by structure and probably function, but not genetic sequence. The findings, published in PNAS, offer a new way of identifying the role of genes in unrelated species and could lead to new ways to fight intestinal bacterial infections.
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Acceptor engineering for NIR-II dyes with high photochemical and biomedical performance
Nature Communications, Published online: 02 July 2022; doi:10.1038/s41467-022-31521-y Small molecule NIR-II fluorophores are of interest for a range of applications but can suffer from chemical and photostability issues. Here, the authors report on the development of an acceptor molecule with improved stability in alkaline conditions expanding the range of possible applications.
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Satellite-tracking of whale sharks offered insight into their migratory and feeding behavior
The largest fish in the ocean is a globe-trotter that can occasionally be found basking in the coastal waters of the Panamanian Pacific. However, little more is known about the habits of the whale shark (Rhincodon typus) in the region. By satellite-tracking the whereabouts of 30 of them, scientists from the Smithsonian Tropical Research Institute (STRI), the Anderson Cabot Center for Ocean Life an
15h
Satellite-tracking of whale sharks offered insight into their migratory and feeding behavior
The largest fish in the ocean is a globe-trotter that can occasionally be found basking in the coastal waters of the Panamanian Pacific. However, little more is known about the habits of the whale shark (Rhincodon typus) in the region. By satellite-tracking the whereabouts of 30 of them, scientists from the Smithsonian Tropical Research Institute (STRI), the Anderson Cabot Center for Ocean Life an
15h
Endosomal LC3C-pathway selectively targets plasma membrane cargo for autophagic degradation
Nature Communications, Published online: 02 July 2022; doi:10.1038/s41467-022-31465-3 Autophagy can selectively target cargo for degradation. Here the authors map the proximal interactome of ATG8-paralogs LC3B and LC3C uncovering an LC3C-Endocytic-Associated-Pathway that selectively recruits internalized plasma membrane cargo, Met and transferrin receptors, to nascent autophagosomes.
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Unveiling the S=3/2 Kitaev honeycomb spin liquids
Nature Communications, Published online: 02 July 2022; doi:10.1038/s41467-022-31503-0 Recently, material realizations of the spin 3/2 Kitaev honeycomb model have been proposed, but the model has not been solved by either analytical or numerical methods. Here the authors report exact results for the spin 3/2 model consistent with numerical simulations, and find gapped and gapless quantum spin liqu
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New York State Buys Robots for Lonely Elders
Robo Buddy More than 800 new robot buddies are headed to their new homes as companions for New York's senior citizens. Smithsonian Magazine reported last week that the bots, called ElliQ, and were designed to assist people 65 and older who live alone. Much like Siri and Alexa, ElliQ can answer questions, make small talk, set reminders and more. "Many features attracted us to ElliQ — that it is a
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For scientists, Roe's end raises concerns about personal safety and professional choices
Demonstrators gathered outside the Supreme Court the morning after the court overturned Roe v. Wade, effectively outlawing abortion in many states. T.J. Kirkpatrick/ The New York Times /Redux When the U.S. Supreme Court overturned Roe v. Wade on 24 June, eliminating the constitutional right to an abortion and handing decisions about abortion access to state legislators, the response across the po
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Googling "Desk Ornament" Returns Images of Nazi Paraphernalia
Ornamental in Nature Are Nazis hiding their paraphernalia under innocuous search terms, or is Google failing to respond to an algorithmic crisis? Either could be true based on today's tweetstorm about WWII-era paperweights and décor. The saga stared yesterday, when former Cracked editor and scifi author Jason Pargin asked followers if they, too, were getting tons of images of Nazi memorabilia whe
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Apple's Entry-Level M2 MacBook Pro Turns Into a Celeron Under Heavy Load
There's an old adage in tech about never buying the first generation of any product. As far as Apple Silicon is concerned, however, you might be better off if you did. Reviewers keep finding new ways that the new, M2-equipped MacBook Pro base system is a weaker product than its predecessor. Now, there's evidence from real-world tests that the M2-equipped base MacBook takes a hefty penalty when fu
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Keeping the energy in the room
It may seem like technology advances year after year, as if by magic. But behind every incremental improvement and breakthrough revolution is a team of scientists and engineers hard at work.
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Study: How placentas evolved in mammals
The fossil record tells us about ancient life through the preserved remains of body parts like bones, teeth and turtle shells. But how to study the history of soft tissues and organs, which can decay quickly, leaving little evidence behind?
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Rock Never Dies—But It Does Get Older and Wiser
Updated at 9:22 a.m. ET on July 2, 2022. This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. Sign up for it here . It's been a week full of ghastly revelations and depressing events, so let's step away from the stress of politics and think about music heading into this holi
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Montana bio station researchers discuss mine risks to salmon rivers
Recently, a group of 23 science and policy experts from the U.S. and Canada published a review of mining risks to watersheds ranging from Montana to British Columbia and Alaska. The paper brought together experts in salmon ecology, watershed science, mining impacts and mining policy to integrate knowledge across research fields that often work independently from one another.
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Keeping the energy in the room
Researchers are developing precision optical sensors for telescopes and observatories. The team has now improved the spectra resolution of their superconducting sensor, a major step in their ultimate goal: analyzing the composition of exoplanets.
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How placentas evolved in mammals
The fossil record tells us about ancient life through the preserved remains of body parts like bones, teeth and turtle shells. But how to study the history of soft tissues and organs, which can decay quickly, leaving little evidence behind? In a new study, scientists use gene expression patterns, called transcriptomics, to investigate the ancient origins of one organ: the placenta, which is vital
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Angry Zuckerberg Complains About Employees Who "Shouldn't Be Here"
Cut the Fat In a further sign of tough times, Meta-formerly-Facebook CEO Mark Zuckerberg is ready to root out the stragglers among his employees. During a Q&A session with Meta staff, Zuckerberg announced that he's "turning up the heat" over performance goals, according to recordings obtained by Reuters . He's hoping the pressure will make them leave, rather than having Meta's managers fire them.
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Bitcoin Just Had Its Worst Month in Crypto's Entire History
Free Fallin' The blockchain blues continue. Bitcoin lost 38 percent of its value in June alone, making this past month the worst in crypto's 12 year history, CNBC reports . That's not all the bad news. Ethereum rang in at an astonishing 47 percent loss, and industry leaders crumbled across the board — major crypto hedge fund Three Arrows Capital has effectively imploded after failing to pay a $67
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What is a good book about holonomics and consciousness?
Hi, I want to read more about how the principle of holonomics can explain consciousness and looking for a good book to read about the subject. I am not schooled in physics or math, so it has to be written for the layman, but at the same time I am capable of grasping complex concepts, so it doesn't have to be introductory in the sense that it only explains the most basic ideas. A book which integr
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Experts Say Travis Barker Colonoscopy Rumor Likely False
Former Blink-182 drummer Travis Barker is reportedly recovering from a bout of pancreatitis brought on by a recent colonoscopy — but doctors say that seems unlikely. Confirmed by TMZ , news of Barker's reported Tuesday hospitalization comes after the famed drummer and newest Kardashian clan member tweeted "God save me" that afternoon. Though the gossip news site reported that doctors believe Bark
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There's a shortage of monkeypox vaccine. Could one dose instead of two suffice?
As the monkeypox outbreak grows, the preferred vaccine to combat it is in short supply—a problem that's only getting worse now that countries are expanding access to the vaccine. But there is a strategy that could double overnight the number of people who can be vaccinated: use a single shot instead of the recommended two. Compelling data from monkey and human studies suggest a single dose of the
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Arrested-motility states in populations of shape-anisotropic active Janus particles
Abstract The emergence of large-scale collective phenomena from simple interactions between individual units is a hallmark of active matter systems. Active colloids with alignment-dominated interparticle interactions tend to develop orientational order and form motile coherent states, such as flocks and swarms. Alternatively, a combination of self-propulsion and excluded-volume interactions resul
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Immunotherapy of glioblastoma explants induces interferon-γ responses and spatial immune cell rearrangements in tumor center, but not periphery
Abstract A patient-tailored, ex vivo drug response platform for glioblastoma (GBM) would facilitate therapy planning, provide insights into treatment-induced mechanisms in the immune tumor microenvironment (iTME), and enable the discovery of biomarkers of response. We cultured regionally annotated GBM explants in perfusion bioreactors to assess iTME responses to immunotherapy. Explants were treat
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Resolving the different bulk moduli within individual soft nanogels using small-angle neutron scattering
Abstract The bulk modulus, K , quantifies the elastic response of an object to an isotropic compression. For soft compressible colloids, knowing K is essential to accurately predict the suspension response to crowding. Most colloids have complex architectures characterized by different softness, which additionally depends on compression. Here, we determine the different values of K for the variou
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Dynamic network of intermolecular interactions in metal-organic frameworks functionalized by molecular machines
Abstract Molecular machines enable external control of structural and dynamic phenomena at the atomic level. To efficiently transfer their tunable properties into designated functionalities, a detailed understanding of the impact of molecular embedding is needed. In particular, a comprehensive insight is fundamental to design hierarchical multifunctional systems that are inspired by biological ce
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Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling
Abstract The mechanistic target of rapamycin–mLST8-raptor complex (mTORC1) functions as a central regulator of cell growth and metabolism in response to changes in nutrient signals such as amino acids. SAMTOR is an S -adenosylmethionine (SAM) sensor, which regulates the mTORC1 activity through its interaction with the GTPase-activating protein activity toward Rags-1 (GATOR1)-KPTN, ITFG2, C12orf66
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Enhanced phosphorus recycling during past oceanic anoxia amplified by low rates of apatite authigenesis
Abstract Enhanced recycling of phosphorus as ocean deoxygenation expanded under past greenhouse climates contributed to widespread organic carbon burial and drawdown of atmospheric CO 2 . Redox-dependent phosphorus recycling was more efficient in such ancient anoxic marine environments, compared to modern anoxic settings, for reasons that remain unclear. Here, we show that low rates of apatite au
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Strong floristic distinctiveness across Neotropical successional forests
Abstract Forests that regrow naturally on abandoned fields are important for restoring biodiversity and ecosystem services, but can they also preserve the distinct regional tree floras? Using the floristic composition of 1215 early successional forests (≤20 years) in 75 human-modified landscapes across the Neotropic realm, we identified 14 distinct floristic groups, with a between-group dissimila
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Measuring competitive exclusion in non–small cell lung cancer
Abstract In this study, we experimentally measure the frequency-dependent interactions between a gefitinib-resistant non–small cell lung cancer population and its sensitive ancestor via the evolutionary game assay. We show that cost of resistance is insufficient to accurately predict competitive exclusion and that frequency-dependent growth rate measurements are required. Using frequency-dependen
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The key micronutrient copper orchestrates broad-spectrum virus resistance in rice
Abstract Copper is a critical regulator of plant growth and development. However, the mechanisms by which copper responds to virus invasion are unclear. We previously showed that SPL9-mediated transcriptional activation of miR528 adds a previously unidentified regulatory layer to the established ARGONAUTE (AGO18)–miR528– L-ascorbate oxidase ( AO ) antiviral defense. Here, we report that rice prom
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Competing and accelerating effects of anthropogenic nutrient inputs on climate-driven changes in ocean carbon and oxygen cycles
Abstract Nutrient inputs from the atmosphere and rivers to the ocean are increased substantially by human activities. However, the effects of increased nutrient inputs are not included in the widely used CMIP5 Earth system models, which introduce bias into model simulations of ocean biogeochemistry. Here, using historical simulations by an Earth system model with perturbed atmospheric and riverin
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Ambient formaldehyde and mortality: A time series analysis in China
Abstract The potential health impact of low-level ambient formaldehyde has been historically overlooked. We conducted a two-stage time series analysis to investigate associations between ambient formaldehyde and daily nonaccidental, circulatory, and respiratory mortality and six subtypes based on 5,325,585 deaths in 275 Chinese counties between 2013 and 2018 and estimated a concentration-response
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New method boosts the study of regulation of gene activity
Researchers report the development of a chemical-based sequencing method to quantify different epigenetic markers simultaneously. Their method, called NT-seq, short for nitrite treatment followed by next-generation sequencing, is a sequencing method for detecting multiple types of DNA methylation genome-wide.
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'Soft' CRISPR may offer a new fix for genetic defects
Scientists have developed a new CRISPR-based technology that could offer a safer approach to correcting genetic defects. The new 'soft' CRISPR approach makes use of natural DNA repair machinery, providing a foundation for novel gene therapy strategies with the potential to cure a large spectrum of genetic diseases.
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7 Theories About Why Elon Musk Has Disappeared
Tesla and SpaceX CEO Elon Musk has been noticeably quiet over the last ten days. It was weird before , and now it's even weirder. The last time the billionaire tweeted was June 21. For Musk, who tends to incessantly tweet at virtually any hour of the day, that's an eternity and a half. He did appear to fly to Rome, Italy last night after spending much of the last ten days in Austin, Texas, the si
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Experts Say Birds Are Catching on Fire on Power Lines and Starting Wildfires
Burning Birds Exploding limbs, burning plumage, bodily water cells instantly turned to steam — electrocution sounds like a terrible way to go. Even worse is the new discovery that when birds on power lines combust from an electric shock and fall to the ground, their dead bodies can cause deadly wildfires. A group of researchers in Colorado published their findings in the journal Wildlife Society
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Environmental justice advocates slam Supreme Court ruling
The Supreme Court decision to limit how the Environmental Protection Agency regulates carbon dioxide emissions from power plants could make an already grave situation worse for those affected most by climate change and air pollution, advocates say.
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New method boosts the study of regulation of gene activity
One way cells can control the activities of their genes is by adding small chemical modifications to the DNA that determine which genes are turned on or off. Methyl groups are one of these chemical modifications or tags. Researchers have found that in bacteria DNA methylation plays a role in regulating virulence, reproduction and gene expression. In other organisms, including humans, DNA methylati
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New method boosts the study of regulation of gene activity
One way cells can control the activities of their genes is by adding small chemical modifications to the DNA that determine which genes are turned on or off. Methyl groups are one of these chemical modifications or tags. Researchers have found that in bacteria DNA methylation plays a role in regulating virulence, reproduction and gene expression. In other organisms, including humans, DNA methylati
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Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31596-7 The role of IL-9 in the tumor microenvironment and its effects on macrophages remains unclear. Here, the authors show that IL-9 promotes the expansion of pulmonary macrophages and that targeting the IL-9R/arginase 1 axis restricts tumor growth, thus identifying this cytokine pathway as a potential therapeutic ta
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Rise of the dinosaurs traced back to their adaptation to cold
Covering of feathers left them able to cope when other creatures died off in mass extinction event, scientists say Fossil hunters have traced the rise of the dinosaurs back to the freezing winters the beasts endured while roaming around the far north. Footprints of the animals and stone deposits from north-west China suggest dinosaurs became adapted to the cold in polar regions before a mass exti
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Did fuzzy coats help dinosaurs survive one of Earth's worst extinctions?
Dinosaurs lived in an endless summer, surrounded by steaming jungles and lush swamps—at least if movies such as Fantasia and Jurassic World are to be believed. But that classic image is changing. Paleontologists now know some dinosaurs lived in comparatively chilly habitats with months of darkness and occasional snow on the ground. Frigid conditions like these, a controversial new study argues, m
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Hidden in genetics: The evolutionary relationships of two groups of ancient invertebrates revealed
Kamptozoa and Bryozoa are two phyla of small aquatic invertebrates. They are related to snails and clams (collectively called mollusks), bristleworms, earthworms, and leeches (collectively called annelids), and ribbon worms (nemertea). But their precise position on the tree of life, and how closely related they are to these other animals, has always puzzled evolutionary biologists. Previous studie
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'Soft' CRISPR may offer a new fix for genetic defects
Curing debilitating genetic diseases is one of the great challenges of modern medicine. During the past decade, development of CRISPR technologies and advancements in genetics research brought new hope for patients and their families, although the safety of these new methods is still of significant concern.
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Dinosaurs took over amid ice, not warmth, says a new study of ancient mass extinction
Many of us know the conventional theory of how the dinosaurs died 66 million years ago: in Earth's fiery collision with a meteorite, and a following global winter as dust and debris choked the atmosphere. But there was a previous extinction, far more mysterious and less discussed: the one 202 million years ago, which killed off the big reptiles who up until then ruled the planet, and apparently cl
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Hidden in genetics: The evolutionary relationships of two groups of ancient invertebrates revealed
Kamptozoa and Bryozoa are two phyla of small aquatic invertebrates. They are related to snails and clams (collectively called mollusks), bristleworms, earthworms, and leeches (collectively called annelids), and ribbon worms (nemertea). But their precise position on the tree of life, and how closely related they are to these other animals, has always puzzled evolutionary biologists. Previous studie
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Dinosaurs took over amid ice, not warmth, says a new study of ancient mass extinction
Many of us know the conventional theory of how the dinosaurs died 66 million years ago: in Earth's fiery collision with a meteorite, and a following global winter as dust and debris choked the atmosphere. But there was a previous extinction, far more mysterious and less discussed: the one 202 million years ago, which killed off the big reptiles who up until then ruled the planet, and apparently cl
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Advocating a new paradigm for electron simulations
Although most fundamental mathematical equations that describe electronic structures are long known, they are too complex to be solved in practice. This has hampered progress in physics, chemistry and the material sciences. Thanks to modern high-performance computing clusters and the establishment of the simulation method density functional theory (DFT), researchers were able to change this situat
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Exploring how adding UV treatment to water chlorination can actually increase toxic trihalomethane production
Halobenzoquinones (HBQs), as new emerging disinfection by-products (DBPs), are frequently detected in potable and swimming pool waters. In fact, HBQs are also precursors of other DBPs such as currently regulated trihalomethanes (THMs), which pose a high risk to the public health and the environment. When UV is applied during the chlorination process, the DBPs formation may be quite different from
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Hearing better with skin than ears
A research team develops a sound-sensing skin-attachable acoustic sensor. The new sensor decreased in size and increased in flexibility and is applicable as auditory electronic skin.
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Floating in space might be fun, but study shows it's hard on earthly bodies
Bone loss happens in humans — as we age, get injured, or any scenario where we can't move the body, we lose bone. Understanding what happens to astronauts and how they recover is incredibly rare. It lets us look at the processes happening in the body in such a short time frame. We would have to follow someone for decades on Earth to see the same amount of bone loss.
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The art of getting DNA out of decades-old pickled snakes
Using pickled snakes collected decades ago and stored in an underground bunker of collections, scientists have found ways to get DNA samples from specimens previously considered near-impossible to get genetic data from. They used that DNA to solve a long-standing mystery about which family an elusive snake from the island of Borneo belongs to.
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Northrop Grumman's Cygnus Spacecraft Successfully Boosts The International Space Station
After a successful attempt to boost the International Space Station into a higher orbit earlier this week, Northrop Grumman's Cygnus NG-17 spacecraft has burned up in a controlled destructive descent. The Cygnus spacecraft — whose official name is the S.S. Piers Sellers , after the late NASA astronaut and climatologist — made berth at the International Space Station (ISS) on February 21. At the t
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Highly-sensitive SERS probes developed to detect the PD-L1 biomarker
Recently, a team led by Prof. Huang Qing at the Institute of Intelligent Machines, Hefei Institutes of Physical Science (HFIPS) of Chinese Academy of Sciences (CAS) has reported the fabrication of ultrasensitive biosensors based on Surface-enhanced Raman Spectroscopy (SERS) to detect the cancer metastasis related programmed death ligand (PD-L1) biomarker.
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A Portrait of the Artist Who Never Makes Art
We encounter Bran, the narrator of Nell Zink's new novel, Avalon , just as she leaves a party where something pivotal and distressing has happened to her. We know that it is pivotal because we immediately cut back in time to Bran's childhood, and much of the novel becomes an inexorable march toward that fateful night. We also have some warning that the account we are about to hear is a fragile me
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Scientists are still fleshing out Darwin's theory of evolution | Letters
There can be no one unifying theory, writes Prof Jonathan Bard , while Nicholas Maxwell looks to the role of purposive actions and Pete Bibby says the fittest theory will survive Stephen Buranyi misses some key points in his article ( Do we need a new theory of evolution?, 28 June ). Darwin saw novel speciation as resulting from natural selection acting on anatomical variants, but that simple ske
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Former Employee Accuses Zuckerberg of Brandishing Ninja Sword When He Was Angry With Programmers
Arrrr! Extremely chill, totally okay behavior alert! In a viral TikTok , a former Facebook coder has alleged that Facebook-turned-Meta CEO Mark Zuckerberg once threatened workers with an katana sword. As for why Zuck felt the need to unsheathe a large, bladed weapon in the office? The video's creator, Noah Kagan, offers the simple reasoning that he "didn't like the code and the stuff we were putt
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Good Buys: Outer Brown Wicker Outdoor Armchair Conversation Set
Whether it's the pristine beaches of San Diego, the bracing salt spray of Ocracoke, or the majestic Aspens of Colorado, let's give nature the respect it deserves. That means buying sustainably. But when it comes to furnishing your outdoor spaces, it can be hard to find the union between the style you want and the sustainability you believe in. Outer aims to fill that niche, creating furniture tha
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Happy BBQ Season! There's Beer Made From Toilet Water Now
Drink Up Beer lovers in Singapore have a new kind of ale to try out — if they're brave enough. Bloomberg reported this week that a beverage called NEWBrew hit the shelves in April this year, and it's made from recycled and treated sewage water. "I seriously couldn't tell this was made of toilet water," one local who bought the beer and gave it a taste test told the financial pub. "I don't mind ha
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Group of Robotaxis All Shut Down at Same Moment, Stopping Traffic for Hours
Maybe Driver More than a half dozen GM Cruise robotaxis shut down simultaneously on a San Francisco street on Tuesday night — a mere week after Cruise officially launched its fare-collecting driverless robotaxi service in the city. The incident caused traffic to build up for hours, until GM employees were able to manually move the vehicles away, TechCrunch reports . It's hilarious, but also an in
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Protecting the brain from dementia-inducing abnormal protein aggregates
Neurodegenerative diseases like Alzheimer's and Parkinson's are defined by pathogenic accumulation of toxic proteins in the brain. Now, however, scientists have established that the p62 protein, which is involved in cellular protein degradation, can prevent the accumulation of toxic oligomeric tau species in mouse brains, proving the 'neuroprotective' function of p62 in a living model.
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Capturing the onset of galaxy rotation in the early universe
After the Big Bang came the earliest galaxies. Due to the expansion of the universe, these galaxies are receding away from us. This causes their emissions to be redshifted (shifted towards longer wavelengths). By studying these redshifts, it is possible to characterize the 'motion' within the galaxies as well as their distance. In a new study, astronomers have now revealed a likely rotational moti
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The case is building that colliding neutron stars create magnetars
Magnetars are some of the most fascinating astronomical objects. One teaspoon of the stuff they are made out of would weigh almost one billion tons, and they have magnetic fields that are hundreds of millions of times more powerful than any magnetic field that exists today on Earth. But we don't know much about how they form. A new paper points to one possible source—mergers of neutron stars.
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What Comes After Roe?
The Atlantic 's executive editor, Adrienne LaFrance, discusses a post- Roe America with two contributing writers. The legal historian Mary Ziegler and the constitutional-law scholar David French answer questions about what happens now that Roe v. Wade has been overturned. How will abortion bans be enforced? What will come of the legal and legislative battle moving to the states? And what other ri
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Don't Worry, It's Not COVID
The maskless man a few rows back was coughing his head off. I had just boarded the train from D.C. to New York City a couple of weeks ago and, along with several other passengers, was craning my neck to get a look at what was going on. This was not the reedy dregs of some lingering cold. This was a deep, constant, full-bodied cough. Think garbage disposal with a fork caught inside. No one said an
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A step on the way to better therapies against viruses
Most cells can defend themselves against viruses after they have been activated by the body's own messenger substances (interferons). This happens with the help of proteins that recognize invading virus components and interfere with virus replication. One of these proteins is the myxovirus resistance protein B (MxB). It can inhibit many viruses, for example HIV and herpes viruses. But until now it
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Study reveals an unprecedented change in Europe's fire regime
A study reveals an unprecedented change in the fire regime in Europe which is related to climate change. The affected areas are in Southern, Central and Northern Europe but this historical change in Europe's fire regime is more intense in the Mediterranean area. The study, published in the journal Scientific Reports, is led by Jofre Carnicer, lecturer of Ecology at the Faculty of Biology, and memb
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Triply eclipsing stellar systems
Stars with the mass of the sun or larger are typically accompanied by one or more orbiting companion stars. The system forms when gravity contracts the gas and dust of an interstellar cloud until clumps develop that are dense enough to coalesce into stars. Multiple stellar systems develop, according to one model, when the cloud has a slight spin. That generates a disk that then fragments to produc
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A step on the way to better therapies against viruses
Most cells can defend themselves against viruses after they have been activated by the body's own messenger substances (interferons). This happens with the help of proteins that recognize invading virus components and interfere with virus replication. One of these proteins is the myxovirus resistance protein B (MxB). It can inhibit many viruses, for example HIV and herpes viruses. But until now it
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Scientists investigate temperature effect on semiconductor optical amplifiers
The effect of temperature on the performance of the semiconductor optical amplifiers (SOAs) is an important research point. Amer Kotb and his colleagues from the Changchun Institute of Optics, Fine Mechanics and Physics of the Chinese Academy of Sciences have for the first time investigated the effect of high temperatures on the performance of various SOAs, including conventional SOAs, carrier res
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Tidal heating could make exomoons much more habitable (and detectable)
Within the solar system, most of our astrobiological research is aimed at Mars, which is considered to be the next-most habitable body beyond Earth. However, future efforts are aimed at exploring icy satellites in the outer solar system that could also be habitable (like Europa, Enceladus, Titan, and more). This dichotomy between terrestrial (rocky) planets that orbit within their a system's habit
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What the end of Roe v. Wade means for reproductive rights and privacy
On June 24, the Supreme Court released a decision in Dobbs v. Jackson Women's Health Organization, upholding the constitutionality of a 2018 Mississippi law banning abortion after 15 weeks of pregnancy. The court also ruled 5-4 to overturn Roe v. Wade, a 1973 decision that protects pregnant people's right to privacy without excessive government restriction.
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Chunky Turtle Spotted Near NASA's Mega Moon Rocket
Big Turtle Between the Roe reversal and the EPA rollback , it's been a pretty grim week. Bright spots have felt few and far between, but this one may shine the brightest: a sizable turtle , which NASA caught mugging in front of their colossal Space Launch System (SLS) megarocket. The SLS is currently standing by at the Kennedy Space Center in Florida, where it just completed — well, technically c
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Anonymous Says It's Hacking Databases to Protect Women Who Get Abortions
It looks like there's more than one hacking collaborative using their digital skills to protest the Supreme Court's decision to overturn Roe vs. Wade . Representatives of famed hacktivist sect Anonymous claims to have deleted revealing — and now, in the wake of the de-legalization of abortion, potentially criminalizing — data from unnamed period tracking apps. "Data from menstrual tracking apps h
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Historical irrigation leaves long-lasting legacies on the prairie
A hallmark of environmental science is understanding how ecosystems respond to global change. Much of this research focuses on short-term ecosystem responses, such as how an ecosystem responds to a sudden onset of drought. But previous conditions can modify that response. In the same way a formative childhood experience might change how an adult responds to stress, legacy effects can change the di
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Historical irrigation leaves long-lasting legacies on the prairie
A hallmark of environmental science is understanding how ecosystems respond to global change. Much of this research focuses on short-term ecosystem responses, such as how an ecosystem responds to a sudden onset of drought. But previous conditions can modify that response. In the same way a formative childhood experience might change how an adult responds to stress, legacy effects can change the di
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It takes three: The genetic mutations that made rice cultivation possible
Rice has a long history as a staple food in Japan and other parts of Asia. The results of a new study by an international research collaboration suggest that the emergence of cultivated rice from wild rice plants is the result of three gene mutations that make the seeds (i.e. the grains of rice) fall from the plant less easily.
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Song swap indicates humpback whales trade culture
Humpback whales can learn incredibly complex songs from whales from other regions, research finds. Jenny Allen, whose doctoral work at University of Queensland's School of Veterinary Science led to the study, says researchers found New Caledonian humpback whales could learn songs from their counterparts from Australia's east coast with remarkable accuracy. "This really indicates a level of 'cultu
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Analysis of diverse double-strand break synapsis with Polλ reveals basis for unique substrate specificity in nonhomologous end-joining
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31278-4 Using X-ray crystallography and nonhomologous end-joining assays, this study reveals structural features within Polλ that provide it with the ability to bridge and stabilize tenuous DNA double-strand break ends, allowing for religation.
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A new method for predicting the 11-year solar cycle strength
Scientists from Skoltech and their colleagues from the University of Graz & the Kanzelhöhe Observatory (Austria), Hvar Observatory (Croatia), and the Belgian Solar-Terrestrial Center of Excellence—SILSO, Royal Observatory of Belgium presented a new method to predict the strength of the 11-year solar cycle. The results are important for anticipating and mitigating space weather effects on astronaut
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How managers of social media platforms could slow the spread of misinformation
A team of researchers at the University of Washington's Center for an Informed Public has found social media platform managers could dramatically reduce the spread of misinformation on their sites by combining just a few simple measures. In their paper published in the journal Nature Human Behavior, the group used Twitter data associated with the 2020 presidential election to create a model capabl
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Leonard Cohen's 'Hallelujah' Belongs to Everyone
In June 1984, at New York's Quadrasonic Sound studios, Leonard Cohen laid down a song he'd spent years writing. "Hallelujah" would eventually join the pantheon of contemporary popular music; at the time, though, the Canadian singer-songwriter may as well have dropped it off the end of a pier. That's because it was included on Various Positions , Cohen's seventh studio album for Columbia, which th
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Plug-and-play test for keeping track of immunity to Sars-CoV-2 variants
Many antibody tests have been developed since the pandemic started, but very few are designed to specifically detect the Sars-CoV-2 neutralizing antibodies which prevent infection. Based on protein complementation, the modular method described here is the first of its kind to measure neutralizing antibodies against variants, from a drop of blood, in under one hour and at low cost.
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How data-driven journalism illuminates patterns of injustice | Alison Killing
A blank spot on a digital map can signal much more than a gap in data — it can mean something is being intentionally hidden. Sharing the remarkable discovery of massive alleged detention camps in Xinjiang, China, Pulitzer Prize-winning journalist Alison Killing shows how governments can obscure human rights abuses by limiting journalist access on the ground — and calls for more reliable open-sou
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Life Helps Make Almost Half of All Minerals on Earth
The impact of Earth's geology on life is easy to see, with organisms adapting to environments as different as deserts, mountains, forests and oceans. The full impact of life on geology, however, can be easy to miss. A comprehensive new survey of our planet's minerals now corrects that omission. Among its findings is evidence that about half of all mineral diversity is the direct or indirect resul
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Land's 'memory' determined scope of awful Dixie Fire
California's Dixie Fire reveals the impact of legacy effects and prescribed burns, report researchers. The 2021 Dixie Fire burned over nearly 1 million acres in California and cost $637 million to suppress, making it the largest and most expensive wildfire to contain in state history. Fire history largely determined how severely the wildfire burned, and low-severity fire treatments had the larges
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Universal optothermal micro/nanoscale rotors
The fundamental rotation of micro and nano-objects is crucial for the functionality of micro and nanorobotics, as well as three-dimensional imaging and lab-on-a-chip systems. These optical rotation methods can function fuel-free and remotely, and are therefore better suited for experiments, while current methods require laser beams with designed intensity profiles or objects with sophisticated sha
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Do video games help or hurt well-being after a job loss?
New research digs into whether video games are a positive or negative influence on well-being for people who are unemployed. Unemployment can have devastating effects on people's psychological and social well-being. The lack of control over one's life and the loss of social connectedness that commonly result from unemployment can become even more severe during a pandemic . To manage the adverse e
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Scientists decipher, catalog the diverse origins of Earth's minerals
A 15-year study led by the Carnegie Institution for Science details the origins and diversity of every known mineral on Earth, a landmark body of work that will help reconstruct the history of life on Earth, guide the search for new minerals and ore deposits, predict possible characteristics of future life, and aid the search for habitable planets and extraterrestrial life.
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Josh and Casey Catch Keith Lying about His Pots! | Deadliest Catch
Stream Deadliest Catch on discovery+ ► https://www.discoveryplus.com/show/deadliest-catch #DeadliestCatch #Discovery #DiscoveryPlus Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Follow Us on TikTok: https://www.tiktok.com/@Discovery We're on Instagram! https://instagram.com/Discovery Join Us on Facebook: https://www.facebook.com/Discovery Follow Us on Twitter: https://twitter.com/Disco
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New Artificial Photosynthesis Method Grows Food With No Sunshine
How can we grow more food using fewer resources? Scientists have been focused on this question for decades if not centuries, as an ever-growing global population necessitates constantly seeking new ways to produce food in sustainable and affordable ways. Here's a question most of us have never contemplated, because it seems so unfathomable: what if crops could grow without sunlight—not vertical f
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Model reveals potential link between gun trends and mass shootings
A new model sheds light on trends in firearm ownership in the United States. Policymakers are faced with an exceptional challenge: how to reduce harm caused by firearms while maintaining citizens' right to bear arms and protect themselves. This is especially true as the Supreme Court has hobbled New York State regulations restricting who can carry a concealed weapon. "The potential link between m
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How reindeer eyes transform in winter to give them twilight vision
Reindeer are loved the world over for their dark, expressive eyes, majestic antlers and magical association with Santa Claus. The moment you learn the cold, hard truth of how Christmas presents arrive under the tree is a harrowing one that blights many a childhood. But reindeer are more special than your cynical older sibling or classmates would have had you believe.
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How reindeer eyes transform in winter to give them twilight vision
Reindeer are loved the world over for their dark, expressive eyes, majestic antlers and magical association with Santa Claus. The moment you learn the cold, hard truth of how Christmas presents arrive under the tree is a harrowing one that blights many a childhood. But reindeer are more special than your cynical older sibling or classmates would have had you believe.
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Waiting for the sun to set to find a rare bird
When most people are just getting home from their workdays, I'm about to start mine. I am a researcher studying the breeding behavior of the Eastern whip-poor-will (Antrostomus vociferus), a cryptic bird that is primarily active after sunset as it forages on the wing for moths. So—for the summer, at least—I also am nocturnal.
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Decrease in CO2 emissions during pandemic shutdown shows it is possible to reach Paris Agreement goals
An international team of researchers has found that the sudden drop in CO2 emissions during the early days of the COVID-19 pandemic demonstrates that it is possible to reduce emissions enough to meet the 1.5 degrees Celsius global temperature increase goal. In their paper published in the journal Nature Geoscience, the researchers describe studying aspects of the sudden drop of CO2 emissions in ea
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Red supergiant stars bubble and froth so much that their position in the sky seems to dance around
Making a 3D map of our galaxy would be easier if some stars behaved long enough to for us to calculate the distances to them. However, red supergiants are the frisky kids on the block when it comes to pinning down their exact locations. That's because they appear to dance around, which makes pinpointing their place in space difficult. That wobble is a feature, not a bug, of these massive old stars
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Here are the most effective things you can do to fight climate change
Limiting global warming to 1.5℃ above pre-industrial levels requires reaching net zero emissions by the middle of this century. This means that, in less than three decades, we need to reverse more than a century of rising emissions and bring annual emissions down to near zero, while balancing out all remaining unavoidable emissions by actively removing carbon from the atmosphere.
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How to find marker genes in cell clusters
Which genes are specific for a certain cell type, i.e., "mark" their identity? With the increasing size of datasets nowadays, answering this question is often challenging. Often, marker genes are simply genes that have been found in specific cell populations. However, many more genes could be characteristic of a particular cell type but remain undiscovered.
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Literature for a Post-Roe World
Dystopian novels, even when their plots seem fantastical, simulate a deeply human experience: the feeling of being at the mercy of your circumstances, your personal control slipping away. When the Supreme Court struck down Roe v. Wade on Friday, I itched to dive into some speculative fiction, to find my grief and anger reflected in a setting both horrifying and familiar. Margaret Atwood exemplifi
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You're Not Allowed to Have the Best Sunscreens in the World
At 36, I am just old enough to remember when sunscreen wasn't a big deal. My mom, despite being among the palest people alive, does not remember bringing it on our earliest vacations, or hearing any mention of sun protection by our pediatrician. The first memories I have of sunscreen are from the day camp that my brother and I attended in the 1990s, where we spent every day on a playground in the
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The Download: a curb on climate action, and post-Roe period tracking
This is today's edition of The Download , our weekday newsletter that provides a daily dose of what's going on in the world of technology. The US Supreme Court just gutted the EPA's power to regulate emissions The news: The Environmental Protection Agency's ability to regulate carbon dioxide and other greenhouse-gas emissions has been dealt a massive blow by the US Supreme Court. What's in the ru
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Pacific salmon are safer but hungrier in big groups
Pacific salmon in larger groups have lower risk of being eaten by predators, research confirms. But for some salmon species, schooling comes at the cost of competition for food, and those fish may trade safety for a meal. The study appears in the journal Science Advances . "With salmon, most people think of them spawning in freshwater streams, but there's also this huge amount of time they spend
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Oh, Say Can You See These Amazing 4th of July Sales
America is celebrating yet another birthday, which means one thing: a massive onslaught of big discounts on home goods, electronics, and lots more. Between hanging out with friends and family, lighting cool fireworks, housing piles of grilled meat, and reflecting on the country's history, don't forget to score these deals that are only available for a limited time. Here's a selection of the best
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Model for Predictive Policing
The premise of the show Person of Interest is that the government has a powerful computer algorithm connected to all data from the surveillance state – social media, phone calls, e-mail, etc., and it uses this information to predict crimes. This, of course, is a massive invasion of privacy, so to get around that the algorithm gives limited information, just the identity of a "person of interest"
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Where's the herd immunity? Our research shows why Covid is still wreaking havoc | Danny Altmann
'Living with the virus' is proving much harder than the early vaccine success suggested: this fight is far from over Danny Altmann is a professor of immunology at Imperial College London We are all so very tired of Covid-19, and there are many other crises to wrestle with. This pandemic has been going on since the beginning of 2020, and a state of hypervigilance can only be maintained for so long
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The Coming Rise of Abortion as a Crime
Before last week, women attempting to have their pregnancies terminated in states hostile to abortion rights already faced a litany of obstacles: lengthy drives, waiting periods, mandated counseling, throngs of volatile protesters. Now they face a new reality. Although much is still unknown about how abortion bans will be enforced, we have arrived at a time when abortions—and even other pregnancy
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Construction Begins on Largest Direct-Air Capture Plant
(Photo: Climeworks) A Swiss startup has broken ground on the world's largest direct-air carbon dioxide capture plant. Climeworks, a technology-based climate solutions company, specializes in building facilities that capture carbon dioxide out of the air and then recycle or dispose of it. Mammoth , its gargantuan new facility, will capture about 36,000 tons of carbon dioxide each year once fully o
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DDX1 vesicles control calcium-dependent mitochondrial activity in mouse embryos
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31497-9 The DEAD box protein DDX1 is known to form large aggregates in the cytoplasm of early mouse embryos. Here the authors identify DDX1-containing vesicles and show that loss of Ddx1 affects their integrity, compromising mitochondria function and causing embryonic lethality.
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Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31573-0 How bacteria sense and respond to nitrogen is a key question in microbial physiology. This work unveils the mechanism by which the central nitrogen metabolic enzyme, glutamine synthetase, directly signals nitrogen availability to the GlnR regulator.
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T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31135-4 Cholesterol efflux is mediated by specific transporters in T cells. Here the authors show that when the ABCA1/ABCG1 cholesterol transporters are absent, peripheral T cell numbers are reduced but activation increased with a premature aging phenotype of T cell senescence and apoptosis in middle aged Ldlr−/− mice.
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Biomarkers of nanomaterials hazard from multi-layer data
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31609-5 Nanomaterials have a range of potential applications, however, toxicity remains a concern, limiting application and requiring extensive testing. Here, the authors report on a predictive framework made using a range of tests linking materials properties with toxicity, allowing the prediction of toxicity from phys
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Astronauts Suffer Significant, Permanent Bone Density Loss in Space
For all the time humanity has existed, every single person has spent their lives under normal Earth gravity — 9.806 meters per second squared. And then, a few decades ago human beings started spending days, then weeks, and then months in freefall. We're only now beginning to understand what living without gravity does to the body, but it's not good. Kinesiologists Leigh Gabel and Steven Boyd from
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Ukraine Has Exposed Russia as a Not-So-Great Power
In times of peace, much of what anyone says about national power is guesswork. Different claims can be based on hopes, prejudices, or even simple self-interest. Analysts and experts can speak confidently about how some states are undoubtedly great powers while others are weak, that some countries are led by strategic geniuses and others by corrupt incompetents. The statements can sound eminently
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Samsung Becomes First Foundry to Begin Production at 3nm
(Photo: Samsung) Last week, rumors surfaced that Samsung would soon claim it had beaten TSMC to the 3nm punch. Yesterday, Samsung confirmed the news with a celebratory press release. It is the first global foundry to begin 3nm silicon production. It's also the first foundry to move beyond FinFET to gate-all-around (GAA) transistors, which is a major achievement. We should note that nowhere in Sam
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February: 'we don't agree there is an issue here.' June: Retracted.
A Springer Nature journal has retracted a paper on hepatitis C infection it had previously corrected for problematic data – but in between the editors declared the case closed. The paper, "The interaction between microRNA-152 and DNA methyltransferase-1 as an epigenetic prognostic biomarker in HCV-induced liver cirrhosis and HCC patients," was published in July 2019 … Continue reading
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Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31457-3 Optimising antibody properties such as affinity can be detrimental to other key properties. Here the authors use machine learning to simplify the identification of antibodies with co-optimal levels of affinity and specificity for a clinical-stage antibody that displays high levels of on- and off-target binding.
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Homogeneous surrogate virus neutralization assay to rapidly assess neutralization activity of anti-SARS-CoV-2 antibodies
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31300-9 Neutralisation assays are key to understanding immune responses to SARS-CoV-2 infection or vaccination. Here, the authors report a surrogate virus neutralization assay called Neu-SATiN, which measures neutralization directly from sera, and allows easy adaptation to variant-specific testing.
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Development of visual response selectivity in cortical GABAergic interneurons
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31284-6 Excitatory neurons in the carnivore and primate visual cortex display orientation selectivity arranged in a modular fashion before the onset of visual experience, but the developmental timeline for visual response selectivity of inhibitory neurons is unknown. Using in vivo calcium imaging in ferret visual cortex
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The US government is developing a solar geoengineering research plan
The White House is developing a research plan that would guide and set standards for how scientists study one of the more controversial ways of counteracting climate change: solar geoengineering. The basic idea is that we might be able to deliberately tweak the climate system in ways that release more heat into space, cooling an otherwise warming planet. The move, which has not been previously re
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För tidigt födda barn klarar skolan bra
Det finns inga skillnader i skolbetyg hos barn som fötts måttligt för tidigt, jämfört med fullgångna barn. Däremot har barn som fötts extremt tidigt generellt sämre skolbetyg. Inlägget dök först upp på forskning.se .
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India bans many single-use plastics to tackle waste
India imposed a ban on many single-use plastics on Friday in a bid to tackle waste choking rivers and poisoning wildlife, but experts say it faces severe headwinds from unprepared manufacturers and consumers unwilling to pay more.
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Which rules evolutionary change: Life or climate?
The fossil record over the last half a billion years shows biodiversity as a zigzagging pattern of species births and extinctions. For decades scientist have attempted to answer the question: Which rules supreme—life or the environment? To explain this macroevolution, scientists have used two opposing theories: the Red Queen versus the Court Jester theory, inspired by the story Alice in Wonderland
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Which rules evolutionary change: Life or climate?
The fossil record over the last half a billion years shows biodiversity as a zigzagging pattern of species births and extinctions. For decades scientist have attempted to answer the question: Which rules supreme—life or the environment? To explain this macroevolution, scientists have used two opposing theories: the Red Queen versus the Court Jester theory, inspired by the story Alice in Wonderland
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A gentler, more precise laser cutting technique
Laser cutting techniques are usually powered by high energy beams, so hot that they melt most materials. Now scientists from McGill University have developed a gentler, more precise technique using low-power visible light.
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Interview: James Poskett on Reframing the History of Science
In "Horizons," a historian of science casts a wider lens on the last five centuries of scientific achievement, highlighting the crucial contributions of Chinese, Japanese, Indian, and African astronomers, mathematicians, evolutionary thinkers, geneticists, chemists, and other non-Western figures.
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How COVID-19 put poverty reduction back on the agenda
Lower income people bore the brunt of the economic repercussions of the COVID-19 pandemic. As a result, efforts to reduce poverty were adopted in Canada and the United States. But how did partisan politics shape each government's response? Exploring the political dynamics at play, a team of researchers including McGill University Professor Daniel Béland, traces the adoption and evolution of anti-p
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Schneider Shorts 1.07.2022 – Old men, new scams
Schneider Shorts 1.07.2022 – with a Welsh Nobelist's new scam, fraudster's German husband and his fountain of youth, a surprise retraction, an unsurprising correction, Cheshire and his fraudsters, and a dirty old man succeeding a dirty old man in Marseille.
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Manipulating polariton condensates by Rashba-Dresselhaus coupling at room temperature
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31529-4 Engineered spin-orbit coupling can induce novel quantum phases in a Bose-Einstein condensate, however such demonstrations have been limited to cold atom systems. Here the authors realize a exciton-polarion condensate with tunable spin-orbit coupling in a liquid crystal microcavity at room temperature.
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Traps and transport resistance are the next frontiers for stable non-fullerene acceptor solar cells
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31326-z Long operational stability is essential to commercialisation of organic solar cells. Here, the authors investigate the thermal degradation of inverted photovoltaic devices based on PM6:Y6 non-fullerene system to reveal that trap-induced transport resistance is primarily responsible for the drop in fill factor.
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RuO2 electronic structure and lattice strain dual engineering for enhanced acidic oxygen evolution reaction performance
Nature Communications, Published online: 01 July 2022; doi:10.1038/s41467-022-31468-0 While water splitting in acid offers higher operational performances than in alkaline conditions, there are few high-activity, acid-stable oxygen evolution electrocatalysts. Here, authors examine electrochemical Li intercalation to improve the activity and stability of RuO2 for acidic water oxidation.
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What's the Opposite of a Vaccine Selfie?
Healthcare workers know they are trusted professionals, and most take that responsibility seriously when sharing their vaccination choices with the public. What term should be used for doctors who use their social media clout to influence others to skip an important vaccine dose? The post first appeared on Science-Based Medicine .
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Photos of the Week: Lightning Rod, Crown Fountain, Lunar Transit
Surfing at a water park in Italy, a wildfire in Greece, a Corpus Christi festival in Colombia, Ivan Kupala day in Russia, a swimming competition in Budapest, a robotic rover on Mount Etna, a Pride parade in Mexico City, National Paddy Day in Nepal, an animatronic dinosaur in China, and much more
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Australia's 10,000 deaths and the paradox of 'Covid normal'
The country has fared better than others – but those on the frontline are still wrestling with the agony of the coronavirus pandemic Not just a number: families of five Australian pandemic victims reflect on loss during Covid Ten thousand Covid deaths and counting … the road to Australia's grim milestone Get our free news app ; get our morning email briefing In August 2020, staff at the Menarock
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Ancient galaxy's spin suggests universe's first stars quickly coalesced into disks
Astronomers have detected the rotation of a galaxy dating back to just 550 million years after the big bang, when the universe was 4% of its current age. The rotation suggests this baby galaxy was not an amorphous blob but rather an organized disk, just like the Milky Way and similar galaxies that have had more than 13 billion years to mature. It's yet more evidence that galaxies grow and evolve
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California's Dixie Fire shows impact of legacy effects, prescribed burns
The 2021 Dixie Fire burned over nearly 1 million acres in California and cost $637 million to suppress, making it the largest and most expensive wildfire to contain in state history. Fire history largely determined how severely the wildfire burned, and low-severity fire treatments had the largest impact on reducing the worst effects of the fire, according to a research team.
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Capturing the onset of galaxy rotation in the early universe
As telescopes have become more advanced and powerful, astronomers have been able to detect more and more distant galaxies. These are some of the earliest galaxies to form in our universe that began to recede away from us as the universe expanded. In fact, the greater the distance, the faster a galaxy appears to move away from us. Interestingly, we can estimate how fast a galaxy is moving, and in t
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Oh Great, Gas AND Solar Prices Are Going Up
Panel Prices One of the most important materials used in solar panel manufacturing has gone up in price — the biggest jump in eight months — just as demand soars. Yesterday, Bloomberg reported that polysilicon , heavily used in solar panel production, rose nearly 5 percent in cost on Wednesday, marking the highest price for the stuff since late 2011. As companies work to lessen their reliance on
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Best Music Production Software in 2022
Whether it's beat-making, EDM production, multi-track recording, or critical audio editing, finding the best music production software for your creative endeavors is all about ensuring that you have the required tools to optimize your workflow without getting bogged down in the details. Some music production software is incredibly simple and best suited for beginners and simple creative tasks, wh
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Researcher Tells AI to Write a Paper About Itself, Then Submits It to Academic Journal
It looks like algorithms can write academic papers about themselves now. We gotta wonder: how long until human academics are obsolete? In an editorial published by Scientific American , Swedish researcher Almira Osmanovic Thunström describes what began as a simple experiment in how well OpenAI's GPT-3 text generating algorithm could write about itself and ended with a paper that's currently being
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Researchers discover new leukemia-killing compounds
Researchers have discovered potential new drugs that target mitochondria in cancer cells. Their study in the journal Leukemia describes the compounds' potential for killing leukemia cells when administered by themselves or in combination with other chemotherapies.
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Borrowed gene helps maize adapt to high elevations, cold temperatures
An important gene in maize called HPC1 modulates certain chemical processes that contribute to flowering time, and has its origins in 'teosinte mexicana,' a precursor to modern-day corn that grows wild in the highlands of Mexico. The findings provide insight into plant evolution and trait selection, and could have implications for corn and other crops' adaptation to low temperatures.
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