Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04824-9 DNA from ancient wolves spanning 100,000 years sheds light on wolves' evolutionary history and the genomic origin of dogs.
The portrait painted yesterday at the January 6 hearing by Cassidy Hutchinson, a top aide to former White House Chief of Staff Mark Meadows, wasn't simply of a criminal president, but of a seditious madman. Even Republican members of Congress who have long supported Donald Trump told reporters, anonymously, that Hutchinson's testimony was "worse than they imagined." They were "stunned" and "left
The violent event that likely preceded our solar system's formation holds the solution to a longstanding meteorite mystery, says new work from Carnegie's Alan Boss published in The Astrophysical Journal.
When the U.S. government released a much-anticipated report on UFOs a year ago, many were perplexed that it couldn't explain 143 of the 144 sightings it examined. (In the single closed case, the report concluded the mystery object was a large, deflating balloon.) "Where are the aliens?" cracked one headline. The truth was still out there. So was any sense of who had conducted the analysis, becaus
Gaming chairs under $100 are the overlooked cherry on top of a great gaming rig. After all, it's a hobby that is usually enjoyed sitting down, whether you game on PC or consoles. Many "gaming chairs" run upwards of a couple thousand dollars, but there are a handful of inexpensive models well within any budget. These chairs come with features you want, and a few you didn't even know you wanted. He
The reverberations of the Supreme Court decision to overturn the abortion-legalizing precedent Roe v. Wade have been swift and severe. Among those immediate consequences? Skyrocketing demand for both abortion and non-abortion emergency contraceptive pills. In other words, it sounds like folks are stockpiling the drugs amid the looming threat to reproductive autonomy. And that also means added str
Two weeks after we reported on the unsuccessful efforts of a researcher at The Ohio State University to have one of his papers retracted for data manipulation, the journal that had been delaying the move has acted. As we wrote earlier this month based on a request for public records, Philip Tsichlis had been urging … Continue reading
Great white shark researchers on Cape Cod are reminding visitors that warmer weather signals not just the start of the busy tourist season, but also the arrival of the region's famous predators.
A newer dating technique using cosmogenic isotopes finds Australopithecus remains from the Sterkfontein caves to be about 1 million years older than previous estimates, potentially changing scientists' understanding of humanity's origins.
Great white shark researchers on Cape Cod are reminding visitors that warmer weather signals not just the start of the busy tourist season, but also the arrival of the region's famous predators.
NASA administrator Bill Nelson said Wednesday the agency will reveal the "deepest image of our universe that has ever been taken" on July 12, thanks to the newly operational James Webb Space Telescope.
The emissions of carbon dioxide (CO2) and methane (CH4)—the most potent greenhouse gases—into the atmosphere from African lakes are reassessed in a study undertaken by the Laboratory of Chemical Oceanography (FOCUS research unit / Faculty of Science). While it was previously assumed that these lakes were significant CO2 sources, it has since been discovered that they really emit very little CO2 bu
Environmental sensors are a step closer to simultaneously sniffing out multiple gases that could indicate disease or pollution, thanks to a Penn State collaboration. Huanyu "Larry" Cheng, assistant professor of engineering science and mechanics in the College of Engineering, and Lauren Zarzar, assistant professor of chemistry in Eberly College of Science, and their teams combined laser writing and
The gut 'microbiomes' of long-dead animals could give researchers surprising insights into how climate change and other factors have shaped the Rocky Mountains and other ecosystems over decades.
NASA's Double Asteroid Redirection Test (DART) mission is the world's first full-scale planetary defense test against potential asteroid impacts on Earth. Researchers now show that instead of leaving behind a relatively small crater, the impact of the DART spacecraft on its target could leave the asteroid near unrecognizable.
This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. Sign up for it here . Yesterday, Cassidy Hutchinson, a former aide for Donald Trump's chief of staff, provided a key piece of evidence connecting Trump to an attempted coup after the 2020 election. We will learn more in th
In the world of electricity, copper is king—for now. That could change with new research from Pacific Northwest National Laboratory (PNNL) that is serving up a recipe to increase the conductivity of aluminum, making it economically competitive with copper. This research opens the door to experiments that—if fully realized—could lead to an ultra-conductive aluminum alternative to copper that would
A new study that leverages historical data has found unique support for a 'safety in numbers' strategy, where Pacific salmon living in larger groups have a lower risk of being eaten by predators. But for some salmon species, schooling comes at the cost of competition for food, and those fish may trade safety for a meal.
A new way to safely deliver carbon monoxide to the body might help fight inflammation. Inspired by molecular gastronomy, researchers incorporated carbon monoxide into foams that can be delivered to the digestive tract.
Although mindfulness originates within an individual, a Virginia Commonwealth University researcher has found the benefits do not end with this person. The real payoffs emerge when an individual's mindfulness is translated into mindful interactions and relationships. Such interactions—infused with intentionality, compassion and presence—can bring about more harmonious and healthy organizations.
The first national guidelines to help K-12 schools create successful, cost-effective approaches to deliver integrated student supports that address both in- and out-of-school barriers to learning—from hunger, to mental health, to basic needs—have been released by a national working group convened by Boston College.
While your smartphone's mobile hotspot may be useful for keeping your laptop and other devices connected while on the road, they have their limitations in speed and the amount of high-speed data. If you travel regularly and need to stay connected, you're going to need a standalone mobile hotspot to meet your needs. These hotspots are offered by the national cell phone carriers and can provide you
Ticket to Ride General Motors just started charging for rides in its new fleet of driverless Cruise model robotaxis in San Francisco last week, and next it plans to expand to other cities. It's a historic moment, and likely a glimpse of things to come. There aren't a lot of companies with fully driverless vehicles on public streets, and even fewer are charging for rides. It was only back in March
It's best known as a deadly poison, but in low doses, carbon monoxide can have therapeutic benefits for conditions like IBS and cancer. Now, researchers may have found a way to deliver the treatment safely in a foam
Larvae of longhorned beetles develop primarily in woody tissue, which is difficult for most organisms to digest. However, longhorned beetle larvae possess special enzymes to break down the various components of the plant cell wall. Researchers have now taken a closer look at a group of digestive enzymes found only in this beetle family. They resurrected the primordial enzymes, which first appeared
Scientists have shown it is possible to reverse a key process that allows pancreatic cancer cells to grow and spread around the body. These findings show that a protein called GREM1 is key to regulating the type of cells found in pancreatic cancer — and manipulating its levels can both fuel and reverse the ability of these cells to change into a more aggressive subtype. Researchers hope, in the f
Fruit flies are known for their sweet tooth, but new research also indicates they may offer hints to how animals sense — and avoid — high concentrations of salt. Using mutant fruit flies, zoologists have identified a new high-salt receptor on the tongue of Drosophila — receptor IR7c. IR7c governs the insects' ability to detect dangerously high concentrations of salt, typically over 0.25 moles p
Engineers have created a new type of semiconductor laser that accomplishes an elusive goal in the field of optics: the ability to maintain a single mode of emitted light while maintaining the ability to scale up in size and power. It is an achievement that means size does not have to come at the expense of coherence, enabling lasers to be more powerful and to cover longer distances for many applic
The skin's top layer contains a diverse set of hundreds of lipid molecules called ceramides with varying chain lengths that play a vital role in its barrier function.
The burst of flavor from summer's first sweet corn and the proud stance of a show dog both testify to the power of domestication. But so does the microbial alchemy that turns milk into cheese, grain into bread, and soy into miso. Like the ancestors of the corn and the dog, the fungi and bacteria that drive these transformations were modified for human use. And their genomes have acquired many of
In the Mediterranean and the Atlantic, the intensity and location of the oceanographic fronts that limit the gene connectivity among populations of marine crabs vary over time. These dynamic changes, described in an article published in the journal Scientific Reports, alter the gene structure of the populations of marine crabs of commercial and gastronomic interest.
In the Mediterranean and the Atlantic, the intensity and location of the oceanographic fronts that limit the gene connectivity among populations of marine crabs vary over time. These dynamic changes, described in an article published in the journal Scientific Reports, alter the gene structure of the populations of marine crabs of commercial and gastronomic interest.
Studying evolution by focusing solely on fossils would leave many questions unanswered, but evolutionary developmental biology (otherwise known as "evo-devo") helps fill in the gaps.
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31294-4 The discovery and control of the synthesis of metal–organic frameworks remains challenging due to the lack of understanding of their nucleation and growth. Here, the authors report a detailed molecular-level mechanism of the formation of MIL-53(Al).
Studying evolution by focusing solely on fossils would leave many questions unanswered, but evolutionary developmental biology (otherwise known as "evo-devo") helps fill in the gaps.
Larvae of longhorned beetles develop primarily in woody tissue, which is difficult for most organisms to digest. However, longhorned beetle larvae possess special enzymes to break down the various components of the plant cell wall. Researchers at the Max Planck Institute for Chemical Ecology in Jena, Germany, have now taken a closer look at a group of digestive enzymes found only in this beetle fa
Unusual punctuation in headlines makes people more likely to share news stories on Facebook, but phrases like "this will blow your mind" are a turn-off, finds a study
A hidden reservoir of red wolf DNA has been found in coyotes in southwestern Louisiana – and it could be used to help the endangered wolves grow their wild population
The way rivers function is significantly affected by how much sediment they transport and where it gets deposited. River sediment—mostly sand, silt, and clay—plays a critical ecological role, as it provides habitat for organisms downstream and in estuaries. It is also important for human life, resupplying nutrients to floodplain agricultural soils, and buffering sea level rise caused by climate ch
Larvae of longhorned beetles develop primarily in woody tissue, which is difficult for most organisms to digest. However, longhorned beetle larvae possess special enzymes to break down the various components of the plant cell wall. Researchers at the Max Planck Institute for Chemical Ecology in Jena, Germany, have now taken a closer look at a group of digestive enzymes found only in this beetle fa
The size of our primary visual cortex and the amount of brain tissue we have dedicated to processing visual information can predict how well we can see, a new study shows. The study in the journal Nature Communications reveals a new link between brain structure and behavior. "We have found that we can predict how well someone can see based on the unique structure of their primary visual cortex,"
The "abortion pill" is a bit of a misnomer. Known formally as medical or medication abortion, it is really two separate drugs—mifepristone, which stops the pregnancy from progressing, followed by misoprostol, which triggers uterus contractions—that together mimic what happens in a miscarriage. And so, in the early days of at-home medication abortion in the 1990s in the U.K. and Sweden, doctors lo
PLUS. Skærpes testkravet til cykelhjelme fra en uheldsbelastning på 20 til 40 km/t, rammer det den populære airbag-cykelhjelm fra Hövding, med en udløsertid på 100 millisekunder, hårdt.
Policymakers are faced with an exceptional challenge: how to reduce harm caused by firearms while maintaining citizens' right to bear arms and protect themselves. This is especially true as the Supreme Court has hobbled New York State regulations restricting who can carry a concealed weapon.
"Ventilation is the way forward," says infectious disease doctor Abraar Karan of Stanford. Here's how to get better air flow at home, in schools and offices — even in gyms — to stave off COVID. (Image credit: Tanishka R./For NPR)
A large multicenter, randomized clinical trial revealed no difference in the risk of endotracheal intubation requirement at 30 days between awake prone positioning and standard positioning for patients with COVID-19 who suffered from acute hypoxemic respiratory failure.
A new analysis suggests that a particular leadership style dubbed 'engaging leadership' can boost employees' engagement and enhance team effectiveness within the workplace.
Winemaking practices in coastal Italy during the Roman period involved using native grapes for making wine in jars waterproofed with imported tar pitch, according to a new study.
Exposure to the air pollution known as fine particulate matter (PM2.5) is associated with an increased risk of having a cluster of multiple chronic diseases, according to a new study.
An new study shows the number of evening grosbeaks using the campus as a migration stop-over site has gone down an average of 2.6% per year over the last four decades, emblematic of population declines across the charismatic songbird's range.
New research analyzes antibiotic resistance patterns, with the aim of finding trends that can help decide which treatment to apply to each type of patient and stop the spread of bacteria.
The evening grosbeak, a noisy and charismatic songbird, once arrived at Oregon State University in springtime flocks so vast an OSU statistics professor estimated there were up to a quarter million of the birds on campus daily.
Few would argue that romantic partners have the potential to shift each other's beliefs and behaviors, but what about their views on climate change specifically? Up until now there's been little analysis of the dynamics of climate change conversations in romantic relationships and how the beliefs of one partner can influence the other.
The evening grosbeak, a noisy and charismatic songbird, once arrived at Oregon State University in springtime flocks so vast an OSU statistics professor estimated there were up to a quarter million of the birds on campus daily.
Cropping systems are one of the most important components in the crop production system, which is intensified to feed a growing global population. Previous studies focused on high yield with less attention to production of nutrients and vitamins for human diet. Since the Green Revolution, a winter wheat-summer maize double cropping system has dominated the North China Plain (NCP), with the increas
Grim Reality On Monday, deadly Russian missiles hit a shopping mall in Kremenchuk, a city in Central Ukraine. The complex was devastated, and the blast was so strong that security cameras were able to capture falling rubble from hundreds of meters away. There were hundreds of civilians inside of the mall at the time, and as of yesterday morning , 18 deaths had been reported. At least 36 people ar
Cropping systems are one of the most important components in the crop production system, which is intensified to feed a growing global population. Previous studies focused on high yield with less attention to production of nutrients and vitamins for human diet. Since the Green Revolution, a winter wheat-summer maize double cropping system has dominated the North China Plain (NCP), with the increas
Nature, Published online: 29 June 2022; doi:10.1038/d41586-022-01781-1 Garments laced with strips that flatten and bend help to cool a hot person or warm a cold one — without battery power.
Nature, Published online: 27 June 2022; doi:10.1038/d41586-022-01777-x Glaciers on the Tibetan Plateau boast a wide diversity of microorganisms, including species found nowhere else.
Testing the longevity of new electric vehicle battery designs could be four times faster with a streamlined approach, researchers report. Their optimization framework could drastically reduce the cost of assessing how battery configurations will perform over the long haul . "By significantly reducing the testing time, we hope our system can help speed up the development of better batteries…" "The
Abstract Redundancy of multinucleated mature osteoclasts, which results from the excessive fusion of mononucleated preosteoclasts (pOCs), leads to osteolytic diseases such as osteoporosis. Unfortunately, the currently available clinical drugs completely inhibit osteoclasts, thus interfering with normal physiological bone turnover. pOC-specific regulation may be more suitable for maintaining bone
Abstract As the only member of the CX3C chemokine receptor subfamily, CX3CR1 binds to its sole endogenous ligand CX3CL1, which shows notable potential as a therapeutic target in atherosclerosis, cancer, and neuropathy. However, the drug development of CX3CR1 is hampered partially by the lack of structural information. Here, we present two cryo–electron microscopy structures of CX3CR1-G i1 complex
Abstract Affective touch is necessary for proper neurodevelopment and sociability. However, it remains unclear how the neurons innervating the skin detect affective and social behaviors. The C low-threshold mechanoreceptors (C-LTMRs), a specific population of somatosensory neurons in mice, appear particularly well suited, physiologically and anatomically, to perceive affective and social touch. H
Abstract In developing countries, outbreaks of zoonotic diseases (ZDs) result from intertwined ecological, socioeconomic, and demographic processes that shape conditions for (i) increased contact between vulnerable human population and wildlife in areas undergoing environmental degradation and (ii) the rapid geographic spread of infections across socially vulnerable regions. In Brazil, recent inc
Abstract Coastal wetlands are not only among the world's most valued ecosystems but also among the most threatened by high greenhouse gas emissions that lead to accelerated sea level rise. There is intense debate regarding the extent to which landward migration of wetlands might compensate for seaward wetland losses. By integrating data from 166 estuaries across the conterminous United States, we
Abstract Correlative Brillouin and Raman microspectroscopy (BRaMS) is applied for the in situ monitoring of the chemical and physical changes of linseed oil during polymerization. The viscoelastic properties of the drying oil throughout the phase transition were determined by Brillouin light scattering (BLS) and joined to the Raman spectroscopic information about the chemical process responsible
Abstract Life on Earth anticipates recurring 24-hour environmental cycles via genetically encoded molecular clocks active in all mammalian organs. Communication between these clocks controls circadian homeostasis. Intertissue communication is mediated, in part, by temporal coordination of metabolism. Here, we characterize the extent to which clocks in different organs control systemic metabolic r
Abstract DNA aptamers have been widely used as biosensors for detecting a variety of targets. Despite decades of success, they have not been applied to monitor any targets in plants, even though plants are a major platform for providing oxygen, food, and sustainable products ranging from energy fuels to chemicals, and high-value products such as pharmaceuticals. A major barrier to progress is a l
Abstract The Permian-Triassic mass extinction severely depleted biodiversity, primarily observed in the body fossil of well-skeletonized animals. Understanding how whole ecosystems were affected and rebuilt following the crisis requires evidence from both skeletonized and soft-bodied animals; the best comprehensive information on soft-bodied animals comes from ichnofossils. We analyzed abundant t
Abstract We report here that nucleus accumbens–associated protein-1 (NAC1), a nuclear factor of the Broad-complex, Tramtrack, Bric-a-brac/poxvirus and zinc finger (BTB/POZ) gene family, is a negative regulator of FoxP3 in regulatory T cells (T regs ) and a critical determinant of immune tolerance. Phenotypically, NAC1 −/− mice showed substantial tolerance to the induction of autoimmunity and gene
Abstract Exposure to cold triggers a spike in cytosolic calcium (Ca 2+ ) that often leads to transcriptional reprogramming in plants. However, how this Ca 2+ signal is perceived and relayed to the downstream cold signaling pathway remains unknown. Here, we show that the CALCIUM-DEPENDENT PROTEIN KINASE 28 (CPK28) initiates a phosphorylation cascade to specify transcriptional reprogramming downstr
Abstract The last known red wolves were captured in southwestern Louisiana and eastern Texas in 1980 to establish a captive breeding population. Before their extirpation, gene flow with coyotes resulted in the persistence of endangered red wolf genetic variation in local coyote populations. We assessed genomic ancestry and morphology of coyotes in southwestern Louisiana. We detected that 38 to 62
Abstract Carbon nanotubes (CNTs) are promising candidates for numerous cutting-edge fields because of their excellent properties. However, the inherent black color of CNTs cannot satisfy the aesthetic/fashion requirement, and the flammability of CNTs severely restricts their application in high-temperature environments with oxygen. Here, we realized a structural coloration of CNTs by coating them
Abstract Oral drug delivery systems have great potential to treat colorectal cancer (CRC). However, the drug delivery efficiency is restricted by limited CRC-related intestine positioning and dense mucus barrier. Here, we present a biological chemotaxis-guided self-thermophoretic nanoplatform that facilitates precise intestinal positioning and autonomous mucus penetration. The nanoplatform introd
Abstract The ParAB S system is essential for prokaryotic chromosome segregation. After loading at parS on the genome, ParB (partition protein B) proteins rapidly redistribute to distances of ~15 kilobases from the loading site. It has remained puzzling how this large-distance spreading can occur along DNA loaded with hundreds of proteins. Using in vitro single-molecule fluorescence imaging, we sh
Abstract Sulfur is an essential element of life that is assimilated by Earth's biosphere through the chemical breakdown of pyrite. On the early Earth, pyrite weathering by atmospheric oxygen was severely limited, and low marine sulfate concentrations persisted for much of the Archean eon. Here, we show an anoxic photochemical mechanism of pyrite weathering that could have provided substantial amo
Abstract The highly ramified arbors of neuronal dendrites provide the substrate for the high connectivity and computational power of the brain. Altered dendritic morphology is associated with neuronal diseases. Many molecules have been shown to play crucial roles in shaping and maintaining dendrite morphology. However, the underlying principles by which molecular interactions generate branched mo
Abstract Retroviruses and long terminal repeat retrotransposons rely on integrase (IN) to insert their complementary DNA (cDNA) into the genome of host cells. Nevertheless, in the absence of IN, retroelements can retain notable levels of insertion activity. We have characterized the IN-independent pathway of Tf1 and found that insertion sites had homology to the primers of reverse transcription,
Abstract The up-regulation of kynurenine metabolism induces immunomodulatory responses via incompletely understood mechanisms. We report that increases in cellular and systemic kynurenine levels yield the electrophilic derivative kynurenine-carboxyketoalkene (Kyn-CKA), as evidenced by the accumulation of thiol conjugates and saturated metabolites. Kyn-CKA induces NFE2 like bZIP transcription fact
Abstract Grouping is ubiquitous across animal taxa and environments. Safety in numbers is perhaps the most cited reason for grouping, yet this fundamental tenet of ecological theory has rarely been tested in wild populations. We analyzed a multidecadal dataset of Pacific salmon at sea and found that individuals in larger groups had lower predation risk; within groups of fish, size outliers (relat
Abstract Breast milk is chock-full of nutrients, immunological factors, and cells that aid infant development. Maternal cells are the least studied breast milk component, and their unique properties are difficult to identify using traditional techniques. Here, we characterized the cells in mature-stage breast milk from healthy donors at the protein, gene, and transcriptome levels. Holistic analys
Abstract An accurate record of preindustrial (pre-1900 CE) sea level is necessary to contextualize modern global mean sea level (GMSL) rise with respect to natural variability. Precisely dated phreatic overgrowths on speleothems (POS) provide detailed rates of Late Holocene sea-level rise in Mallorca. Statistical analysis indicates that sea level rose locally by 0.12 to 0.31 m (95% confidence) fr
Abstract Polyethylene glycol (PEG)–based conformal coating (CC) encapsulation of transplanted islets is a promising β cell replacement therapy for the treatment of type 1 diabetes without chronic immunosuppression because it minimizes capsule thickness, graft volume, and insulin secretion delay. However, we show here that our original CC method, the direct method, requiring exposure of islets to
Abstract Immune checkpoint inhibitors exhibit limited response rates in patients with triple-negative breast cancer (TNBC), suggesting that additional immune escape mechanisms may exist. Here, we performed two-step customized in vivo CRISPR screens targeting disease-related immune genes using different mouse models with multidimensional immune-deficiency characteristics. In vivo screens character
Abstract Currently, psychiatric diagnoses are, in contrast to most other medical fields, based on subjective symptoms and observable signs and call for new and improved diagnostics to provide the most optimal care. On the basis of a deep learning approach, we performed unsupervised patient stratification of 19,636 patients with depression [major depressive disorder (MDD)] and/or schizophrenia (SC
In a pilot project exploring ways to monitor COVID-19, University at Buffalo scientists hunted for pharmaceuticals and viral RNA simultaneously in wastewater in Western New York.
Companies selling ethical and sustainable products should use up-tempo major mode music in their marketing to help well-meaning consumers convert their good intentions into actual purchases, new research shows.
Researchers are learning more about how special regulatory T cells can impact the immune system's response and how those cells could be manipulated for potential treatments for food allergies and autoimmune disease.
When heat waves hit, they don't just take a toll on people — plants suffer too. That's because when temperatures rise, certain plant defenses don't work as well, leaving them more susceptible to attacks from pathogens and pests. Scientists say they have identified a specific protein in plant cells that explains why immunity falters as the mercury rises. They've also figured out a way to bolster p
Mitochondria are the power plants of cells, and they contain their own genetic material and RNA molecules. Scientists have now discovered that certain modifications in mitochondrial RNA boost the invasive spread of cancer cells by supporting protein synthesis in mitochondria. They have established that a specific gene expression signature correlating with high levels of mitochondrial RNA modificat
Researchers have found that organic vapor can dissolve molecular salts in a phenomenon known as organic deliquescence. Similar to how water vapor can induce deliquescence of compounds like calcium chloride, this phenomenon will be useful for developing methods for capturing harmful volatile organic compounds (VOCs). There is an urgent need to remove them from indoor environments, particularly indu
A new study reassesses emissions of carbon dioxide and methane into the atmosphere from African lakes. While it was previously assumed that these lakes were significant carbon dioxide sources, it has since been discovered that they really emit very little carbon dioxide but a lot of methane, adding to the emissions burden.
During former President Donald Trump's second impeachment, even when Republicans insisted that the assault on the Capitol was an unfortunate consequence of heated rhetoric, most did not attempt to defend Trump's conduct on the merits. Instead, they relied on the absurd technicality that the president was no longer in office, and therefore could not be convicted. That was the rationale of Senate R
Much of the music that defined my early-2000s adolescence was written before I could walk. Listening to CD-Rs filled with songs that had been ripped from the internet, my friends and I warbled to the Pixies' 1988 oddity "Where Is My Mind?," moped to Tears for Fears' 1982 dirge "Mad World" (and its 2001 cover by Gary Jules and Michael Andrews), and mewled to various versions of Leonard Cohen's 198
A recent publication from researchers at the University of Kentucky explains the importance of identifying and understanding how differences between tissues and cells alter gene expression without changing the underlying genetic code.
A recent publication from researchers at the University of Kentucky explains the importance of identifying and understanding how differences between tissues and cells alter gene expression without changing the underlying genetic code.
Researchers have found that organic vapor can dissolve molecular salts in a phenomenon known as organic deliquescence. Similar to how water vapor can induce deliquescence of compounds like calcium chloride, this phenomenon will be useful for developing methods for capturing harmful volatile organic compounds (VOCs). There is an urgent need to remove them from indoor environments, particularly indu
A new study from the University at Buffalo is helping researchers understand how women in their early college years can use friends-based strategies to help avoid unwanted sexual experiences.
In a study of eye fluid from 38 patients, researchers say they have found that levels of a specific protein appears to help accurately predict whether people with the wet form of age-related macular degeneration may need lifelong, frequent eye injections to preserve vision or if they can be safely weaned off the treatments.
New research reveals that a factory-calibrated continuous glucose monitor (CGM) may be sufficiently accurate for use by people on dialysis, a group often plagued by dangerous swings in blood-sugar levels.
Sensing with levitated nanoparticles has so far been limited by the precision of position measurements. Now, researchers have demonstrated a new method for optical interferometry in which light scattered by a particle is reflected by a mirror. This opens up new possibilities for using levitated particles as sensors, in particular, in quantum regimes.
Researchers are studying how a combination of genetics and brain MRIs may be used to predict the chances of developing Alzheimer's disease in the future.
The current system of chemical risk assessment is inadequate and underestimates levels of flame retardants and other pollutants needed to cause harmful health effects, according to a recent analysis.
From the moment the attack on the Capitol began, on January 6, 2021, Donald Trump's moral culpability was clear. That mob would never have assembled on the National Mall but for Trump's decision to relentlessly lie about the results of the 2020 election. His legal culpability, however, was more ambiguous. We did not possess any evidence that he directly coordinated with the rioters prior to the i
On a drizzly day in July 1920, a Colorado scientist named Junius Henderson was hiking around the Dakota Hogback, a sandstone ridge north of Boulder. There, he spotted a group of Rocky Mountain snails (Oreohelix strigosa) oozing across the ground. Henderson scooped up the mollusks and brought them back to his lab at what is now called the University of Colorado Museum of Natural History, carefully
The current system of chemical risk assessment is inadequate and underestimates levels of flame retardants and other pollutants needed to cause harmful health effects, according to a recent analysis.
On a drizzly day in July 1920, a Colorado scientist named Junius Henderson was hiking around the Dakota Hogback, a sandstone ridge north of Boulder. There, he spotted a group of Rocky Mountain snails (Oreohelix strigosa) oozing across the ground. Henderson scooped up the mollusks and brought them back to his lab at what is now called the University of Colorado Museum of Natural History, carefully
Huffing Insolvents Crypto billionaire and founder of exchange FTX Sam Bankman-Fried is pouring hundreds of millions of dollars into cryptocurrency exchanges to keep them from going under amid a growing crypto crisis, Forbes reports . In fact, he argues, the crypto exchange market has already slid far further than executives are willing to admit. "There are some third-tier exchanges that are alrea
MTV's Bunk'd Instead of turning air travel into an absolute hell hole , Air New Zealand has decided to flip the script and, you know, make it more comfortable. As of 2024, the airline says it'll be offering full bunk beds to its Economy class passengers — not just for the wealthy at the front of the plane — in a welcoming option for those stuck on a long haul flight. According to New Zealand broa
Telescopes designed to operate in space have to be constructed differently than those meant to operate on the ground. But what about telescopes that operate in between?
The perception of music in major keys as happy and minor keys as sad is not universal, Australian researchers say Get our free news app , morning email briefing and daily news podcast What makes a piece of music seem happy or sad? Whether it has been composed in a major or minor key is a significant factor. It's part of what distinguishes the cheeriness of Walking on Sunshine from the pensiveness
American Heart Association's checklist to measure cardiovascular health is updated, now called Life's Essential 8™, adding healthy sleep as essential for optimal cardiovascular health. Other health and lifestyle factors in the checklist, which were part of the previous, 7-item scoring tool, are nicotine exposure, physical activity, diet, weight, blood glucose, cholesterol and blood pressure. The n
Researchers found the U.S. population is well below optimal levels of cardiovascular health after applying the Life's Essential 8™ cardiovascular health scoring, the American Heart Association's updated metrics to measure heart and brain health. Life's Essential 8™ scoring was calculated using data from more than 23,400 adults and children from national health surveys from 2013-2018. Results show
There is considerable variation in the management of mantle cell lymphoma across different clinical settings, and some strategies do not always conform with what might be expected, according to a recent analysis.
In a new study, researchers have sampled the fecal microbiomes across diverse geographical populations of dogs to better understand what they look like around the world.
A study of 4,000 Facebook posts by news organizations provides unique insights into clickbait and user engagement. The study, published in the open access journal PLOS ONE by Anna-Katharina Jung, of the University of Duisburg-Essen, and colleagues, suggests both headlines and the text used in the posts can 'bait' users into interacting with a post, though some techniques are more successful than o
A new analysis suggests that a particular leadership style dubbed "engaging leadership" can boost employees' engagement and enhance team effectiveness within the workplace. Greta Mazzetti of the University of Bologna, Italy, and Wilmar Schaufeli of Utrecht University in the Netherlands present these findings in the open-access journal PLOS ONE on June 29, 2022.
Animals that live in groups tend to be more protected from predators. That idea might be common sense, but it's difficult to test for some species, especially for wild populations of fish that live in the ocean.
Researchers studying ancient sea bed burrows and trails have discovered that bottom burrowing animals were among the first to bounce back after the end-Permian mass extinction.
Winemaking practices in coastal Italy during the Roman period involved using native grapes for making wine in jars waterproofed with imported tar pitch, according to a study published June 29, 2022 in PLOS ONE by Louise Chassouant of Avignon University and colleagues.
Animals that live in groups tend to be more protected from predators. That idea might be common sense, but it's difficult to test for some species, especially for wild populations of fish that live in the ocean.
Researchers studying ancient sea bed burrows and trails have discovered that bottom burrowing animals were among the first to bounce back after the end-Permian mass extinction.
Increased flooding in the United States is exposing more people to industrial pollution, especially in urban areas that are home to marginalized communities, according to a new study. The study combined historical data on former hazardous manufacturing facilities with informed predictions on future flood risk in six different American cities, including Providence, Rhode Island; Houston ; New Orle
A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery. Led by Jun Wang, Associate Professor of Biomedical Engineering at Stony Brook University, this microchip assay—called the single-cell cyclic multiplex in situ tagging (CycMIST) technology—may help to advance fields such as molecular diagno
A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery. Led by Jun Wang, Associate Professor of Biomedical Engineering at Stony Brook University, this microchip assay—called the single-cell cyclic multiplex in situ tagging (CycMIST) technology—may help to advance fields such as molecular diagno
On the freezing, dry surface of Mars, small disturbances in the thin atmosphere frequently spin up whirlwinds that dance across dunes and plains, kicking up light dust and leaving dark trails. These dust devils and their swirling tracks have been observed by rovers and orbiters for many years now, as scientists learn more about Mars's atmospheric system and its surface features. The whirlwinds la
New research at the intersection of how humans and ecosystems interact with water shows that the most-stressed regions in the world are becoming drier, leading to water governance, economic and social challenges.
Ask any space explorer, and they'll have a favorite photograph or two from their mission. For Katie Stack Morgan, the deputy project scientist for NASA's Perseverance Mars rover, the first close-up image of layered rocks at the base of Jezero Crater's ancient river delta holds a special place in her heart. The image of the "Enchanted Lake" rocky outcrop, informally named after a landmark in Alaska
How is climate change affecting the permanently frozen soils of the Arctic? What will the consequences be for the global climate, human beings, and ecosystems? And what can be done to stop it?
Researchers surveyed a nationally representative sample of 2,000 U.S. residents to gauge public acceptance of gene-edited foods. Social factors like food beliefs and trust in institutions played a big role in the participants' willingness to eat or actively avoid products made with gene-editing technologies.
Artificial intelligence — and the robots it powers — are often thought of as objective, impartial thinking machines. But can that ever really be the case when us flawed humans are the ones programming them? An experiment published this week by researchers from John Hopkins University, the Georgia Institute of Technology, and the University of Washington found that their robot — controlled by a po
Nature, Published online: 29 June 2022; doi:10.1038/d41586-022-01763-3 But scientists warn that the findings do not mean that children should not be vaccinated against COVID-19.
Researchers have shown that a new mid-infrared spectrometer can precisely measure the ratios of different forms of water—known as isotopologues—in atmospheric water vapor through open air in a little over 15 minutes. Isotopologue ratios, which can be affected by land-based water evaporation and plant transpiration, are used to develop models of climate change and to understand how water is transpo
The continuing geopolitical risk and uncertainty experienced in recent years has prompted companies to change their global supply chains in profound ways, new research has found.
The energy crisis caused by Russia's war in Ukraine is testing Western leaders' promises to phase out natural gas financing abroad — Read more on ScientificAmerican.com
Forest pathologist Martin MacKenzie strode forward on a narrow path through California's mythic bristlecone pine forest in the White Mountains near the Nevada border, methodically scanning gnarled limbs for the invaders that threaten the lives of some of the world's oldest trees.
Forest pathologist Martin MacKenzie strode forward on a narrow path through California's mythic bristlecone pine forest in the White Mountains near the Nevada border, methodically scanning gnarled limbs for the invaders that threaten the lives of some of the world's oldest trees.
Mass-spectrometry based proteomics is the big-data science of proteins that allows the monitoring of the abundance of thousands of proteins in a sample at once. Therefore, it is a particularly well-suited readout for discovering which proteins are targeted by any small molecule. An international research team has investigated this using chemical proteomics.
Mass-spectrometry based proteomics is the big-data science of proteins that allows the monitoring of the abundance of thousands of proteins in a sample at once. Therefore, it is a particularly well-suited readout for discovering which proteins are targeted by any small molecule. An international research team has investigated this using chemical proteomics.
This summer Maryland will impose new restrictions on crabbing in the Chesapeake Bay—including the first-ever limits on how many bushels of male blue crabs watermen can haul each day—in response to a troubling decline in the population of the beloved crustaceans.
This summer Maryland will impose new restrictions on crabbing in the Chesapeake Bay—including the first-ever limits on how many bushels of male blue crabs watermen can haul each day—in response to a troubling decline in the population of the beloved crustaceans.
In the Mediterranean and the Atlantic, the intensity and location of the oceanographic fronts that limit the gene connectivity among populations of marine crabs vary over time. These dynamic changes alter the gene structure of the populations of marine crabs of commercial and gastronomic interest.
A remarkable new species of carnivorous plant was discovered in a remote part of Borneo. It is the first pitcher plant known to produce functional underground traps, and the first for which capture of subterranean prey has been observed. While the traps themselves are often a rich maroon colour, they are produced on shoots that are entirely white, owing to their lack of chlorophyll.
Although mindfulness originates within an individual, a new study has found the benefits do not end with this person. The real payoffs emerge when an individual's mindfulness is translated into mindful interactions and relationships. Such interactions — infused with intentionality, compassion and presence — can bring about more harmonious and healthy organizations.
An international group of geneticists and archaeologists have found that the ancestry of dogs can be traced to at least two populations of ancient wolves. The work moves us a step closer to uncovering the mystery of where dogs underwent domestication, one of the biggest unanswered questions about human prehistory.
A dramatic outbreak of kelp-eating sea urchins along the Central Coast of California in 2014, leading to a significant reduction in the region's kelp forests, was driven primarily by the emergence of sea urchins from their hiding places rather than an increase in the urchin population. In subsequent years, sea urchin movements enabled kelp forest recovery at sites that had been denuded 'urchin bar
Astrophysicists have developed the first 3D simulation of the entire evolution of a jet — from its birth by a rotating black hole to its emission far from the collapsing star. Simulation shows that as the star collapses, its material falls on the disk that swirls around the black hole. This falling material tilts the disk, and, in turn, tilts the jet, which wobbles as it struggles to return to it
Researchers have simulated SARS-CoV-2 infection in human lungs, thereby generating key insights into the mechanisms involved. Using cultured lung tissue samples, the researchers showed that the virus responsible for COVID-19 has only limited capacity for directly infecting cells within human alveoli. The majority of viruses which reach the lungs are ingested by macrophages (cells of the innate imm
Researchers explore a basic building block used in the fabrication of many DNA nanoforms. Known as a Holliday junction, this nexus of two segments of double stranded DNA has been used to form elaborate, self-assembling crystal lattices at the nanometer scale, (or roughly 1/75,000th the width of a human hair).
At the Global Fact international fact-checkers' conference I attended in Oslo earlier this month, there were workshops on digital investigation, lectures on media literacy, even sessions devoted to hateful social media of the kind that sometimes gets directed at people who check facts for a living—and there are many such people. Fact-checking is now a sophisticated, high-tech profession, with mem
Researchers explore a basic building block used in the fabrication of many DNA nanoforms. Known as a Holliday junction, this nexus of two segments of double stranded DNA has been used to form elaborate, self-assembling crystal lattices at the nanometer scale, (or roughly 1/75,000th the width of a human hair).
What we thought we knew about carnivorous plants was swiftly called into question after scientists discovered a new species in the Indonesian province of North Kalimantan, on the island of Borneo. Nepenthes pudica is what scientists call a pitcher plant—it has modified leaves known as pitfall traps or pitchers, where it captures its prey. In a strategy so far unknown from any other species of carn
Levitated nanoparticles are promising tools for sensing ultra-weak forces of biological, chemical or mechanical origin and even for testing the foundations of quantum physics. However, such applications require precise position measurement. Researchers at the Department of Experimental Physics of the University of Innsbruck, Austria, have now demonstrated a new technique that boosts the efficiency
What we thought we knew about carnivorous plants was swiftly called into question after scientists discovered a new species in the Indonesian province of North Kalimantan, on the island of Borneo. Nepenthes pudica is what scientists call a pitcher plant—it has modified leaves known as pitfall traps or pitchers, where it captures its prey. In a strategy so far unknown from any other species of carn
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31473-3 Susceptibility to pneumonia has a genetic component, but specific genes involved remain poorly understood. In this study, genetic signals associated with pneumonia susceptibility are identified, providing information about disease biology and potential targets for treatment.
FuseBot is a new robotic system that fuses visual information and radio-frequency signals to efficiently find hidden items buried under a pile of objects, whether or not the targeted item has an RFID tag.
To solve a long-standing puzzle about how long a neutron can 'live' outside an atomic nucleus, physicists entertained a wild but testable theory positing the existence of a right-handed version of our left-handed universe. They designed a mind-bending experiment to try to detect a particle that has been speculated but not spotted. If found, the theorized 'mirror neutron' — a dark-matter twin to t
In the summer of 2020, Andy Rattinger went on a video date with a woman he met on an app. He had such a nice time that he planned a second date, dinner over Zoom, with her. He then suggested that they order identical London-themed Lego sets and build them simultaneously from their respective living rooms, while also talking on Zoom. The activity opened up conversations about her time in the U.K.
Beware, Recruiters! People aren't just using impressive deepfakes to troll Robert Pattinson , create endearing videos of a lookalike Margot Robbie , or to sing onstage as famed pessimist Simon Cowell . Yesterday, the FBI issued an ominous warning , spotted by Gizmodo , that deepfakes — coupled with stolen personal information — are increasingly being used to apply for a variety of work from home
The best computer speakers are almost guaranteed to be a big step up in audio quality over the audio hardware built into your desktop or laptop. Your computer's built-in speakers are limited by space constraints, which isn't the case when you plug in an external pair. Computer speakers have come a long way from the days of nondescript-looking boxes that came bundled with tower PCs in the 90s. Tod
On Autopilot It's been eight days since Tesla CEO Elon Musk's last tweet. And judging by the latest news coming out of the electric carmaker, that may be because Musk has his hands full with unmitigated chaos. Bloomberg is now reporting that the company is gutting part of its Autopilot department, cutting around 200 jobs from an office in San Mateo, California, in a potentially significant blow t
Using a multi-species experimental approach, researchers from the Institute of Botany of the Chinese Academy of Sciences (IBCAS) have recently found that trade-off between current reproduction and future performance was associated with flowering strategy and clonality. Results were published in the Journal of Ecology.
Using a multi-species experimental approach, researchers from the Institute of Botany of the Chinese Academy of Sciences (IBCAS) have recently found that trade-off between current reproduction and future performance was associated with flowering strategy and clonality. Results were published in the Journal of Ecology.
More than 50 years after the discovery of the first pulsar, the detailed physics of the emission process in a pulsar magnetosphere still remains unclear.
A research team led by Jiang Zhizhong from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS) has found a honeycomb structure in localized regions at the top of the magnetite layer on martensitic steel and analyzed its formation reason and process.
A new study finds that investors want to be compensated, in the form of higher returns, for holding the stock of firms that have a relatively higher proportion of short-term debt, rather than long term debt
A new study shows how two major pathways — AKT and NMD (nonsense-mediated mRNA decay) — interact in the context of fragile X syndrome. Researchers also found that Afuresertib, a drug currently being tested in phase 1 and 2 clinical trials for several types of cancer, inhibits both pathways in neural stem cells that mimic the disease, leading the cells to act more like typical, non-disease cells.
Researchers have discovered that aggressive tumors contain highly active cells that move throughout tissue in complicated patterns. What's more, the accumulations of these elongated, spindle-like cells found throughout the tumor, coined 'oncostreams,' serve as the basis for cancerous cells' behavior, determining how tumors grow and invade normal tissue.
Similar to the vaccines against the coronavirus, RNA-based antibiotics could significantly improve modern medicine. Research teams have investigated the prerequisites that such antibiotics must meet for this strategy to work.
Targeting a gene in pancreatic beta cells could disrupt the chain of events that leads to the immune system destroying those cells and causing type 1 diabetes. This new study looks at the role of the beta cells themselves in triggering autoimmunity. The research also raises the possibility that new medications could block the immune system from destroying beta cells and prevent type 1 diabetes fro
Researchers have developed a word-score model capable of estimating the amount of hidden hearing loss in human ears using ordinary speech scores from hearing tests. Currently hidden hearing loss, or cochlear nerve degeneration, cannot be measured by an audiogram.
Lamivudine, a commonly-used antiretroviral drug for treating HIV, improves cognition in a mouse model of Down syndrome, according to the findings of a new study. Though clinical studies are necessary to confirm that the drug elicits a similar effect in humans, the findings pave the way for pharmacological treatments that rescue the relatively rapid cognitive decline in people with Down syndrome th
Engineers have created a new liver tissue model that allows them to trace the steps involved in liver regeneration more precisely than has been possible before.
Extrusion-based 3D printing of bio solids, or "bioprinting," is a promising approach to generating patient-specific, tissue-engineered grafts. However, a major challenge in bioprinting is that most currently used materials lack the versatility to be used in a wide range of applications.
In the fall of 2023, a U.S. rover will land at the south pole of the moon. Its mission: to explore the water ice that scientists know lurks within the lunar shadows, and which they believe could help sustain humans who may one day explore the moon or use it as a launching pad for more distant space exploration.
A white mineral ring as tall as the Statue of Liberty creeps up the steep shoreline of Lake Mead, a Colorado River reservoir just east of Las Vegas on the Nevada-Arizona border. It is the country's largest reservoir, and it's draining rapidly.
Norovirus lives in the gut – but mouse studies suggest it may also survive in salivary glands, and the discovery implies there are additional measures we could take to limit infections
With Roe v. Wade overturned, banning abortion in many states could lead to a large number of ob-gyns avoiding practicing there or failing to receive crucial medical training — Read more on ScientificAmerican.com
With Roe v. Wade overturned, banning abortion in many states could lead to a large number of ob-gyns avoiding practicing there or failing to receive crucial medical training — Read more on ScientificAmerican.com
With Roe v. Wade overturned, banning abortion in many states could lead to a large number of ob-gyns avoiding practicing there or failing to receive crucial medical training — Read more on ScientificAmerican.com
A Northwestern University-led team of astrophysicists has developed the first-ever full 3D simulation of an entire evolution of a jet formed by a collapsing star, or a "collapsar."
It sounds like one of the easiest experiments possible: Take two cups of water, one hot, one cold. Place both in a freezer and note which one freezes first. Common sense suggests that the colder water will. But luminaries including Aristotle, Rene Descartes and Sir Francis Bacon have all observed that hot water may actually cool more quickly. Likewise, plumbers report hot water pipes bursting in.
NASA has big plans for the next decade as humanity returns to the moon decades after the end of the Apollo program. While the agency is still fiddling with the Space Launch System (SLS) rocket at the heart of the new Artemis program , it's already making plans for the Lunar Gateway station. It all starts with the newly launched CAPSTONE mission, which will test that station's proposed orbit aroun
Where and when dogs arose is one of the biggest mysteries of domestication . To solve it, researchers have tried everything from analyzing ancient dog bones to sequencing modern dog DNA—all with inconclusive results. Now, researchers have tried a new tack: figuring out where the ancient wolves that gave rise to dogs lived. The new study doesn't close the case, but it does point to a broad geograp
Though Alain Pierre-Louis grew up in a Haitian family that attended Catholic church services most Sundays, he always felt a spiritual pull toward something else. Vodou, a Haitian religion rooted in ancestral remembrance, nature, healing, and justice, was embedded everywhere in his Boston childhood—in the traditional rasin , or "roots," music blaring from the living-room speakers, and in the Haiti
The Universidad Carlos III de Madrid (UC3M) is conducting research that analyzes antibiotic resistance patterns with the aim of finding trends that can help decide which treatment to apply to each type of patient and stop the spread of bacteria. This study, recently published in the scientific journal Nature Communications, has been carried out together with the University of Exeter, the Universit
The Universidad Carlos III de Madrid (UC3M) is conducting research that analyzes antibiotic resistance patterns with the aim of finding trends that can help decide which treatment to apply to each type of patient and stop the spread of bacteria. This study, recently published in the scientific journal Nature Communications, has been carried out together with the University of Exeter, the Universit
Terrestrial and marine habitats have been considered the ecosystems with the highest primary production on Earth by far. Microscopic algae in the upper layers of the oceans and plants on land bind atmospheric carbon (CO2) and produce plant material driven by photosynthesis. Since sunlight does not penetrate into the subsurface, hardly any such primary production is to be expected.
Nature, Published online: 29 June 2022; doi:10.1038/d41586-022-01809-6 A new transmission route for gastrointestinal viruses, and an exotic kind of matter made from just neutrons.
Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04861-4 To perch safely, large birds minimize the distance flown after stalling when swooping up from a dive to a perch, but not the time or energy required.
Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04838-3 Cryo-electron microscopy structure, molecular dynamics and biochemical analyses of the SHOC2–PP1C–MRAS complex demonstrate the dependence of the complex formation on RAS–GTP and identify the determinants of RAS isoform preference for SHOC2–PP1C and specificity of the complex for RAF dephosphorylation.
Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04784-0 Hypocrystalline ceramic aerogels with a zig-zag architecture show high thermal stability under thermal shock and exposure to high temperature, providing a reliable material system for thermal insulation at extreme conditions.
Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04911-x Structures of the Dcr-2–Loqs-PD complex while it is processing a double-stranded RNA (dsRNA) substrate elucidate the interactions between Dcr-2 and Loqs-PD, and show that Dcr-2 undergoes substantial conformational changes during a dsRNA-processing cycle.
Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04883-y Structural and biophysical analysis of the Arabidopsis thaliana auxin transporter PIN8 reveal that PIN transporters export auxin using an elevator mechanism.
Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04888-7 The BMP inhibitor GREM1 is a key regulator of cellular heterogeneity in pancreatic cancer in human and mouse.
Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04895-8 Enteric viruses replicate in salivary glands, can be propagated in salivary gland-derived spheroids and cell lines, and are released into saliva, which is a new transmission route having implications for therapeutics, diagnostics and sanitation measures.
Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04902-y Suppression of salicylic acid production in Arabidopsis thaliana at high temperature is caused by decreased recruitment of GUANYLATE BINDING PROTEIN-LIKE 3 defence-associated condensates on promoter sites of master immune regulatory genes.
Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04846-3 By intercalating layered 2D atomic crystals with selected chiral molecules, a new class of chiral molecular intercalation superlattices is reported, demonstrating highly ordered structures and achieving high tunnelling magnetoresistance and spin polarization ratios.
Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04924-6 tDeclining YAP/TAZ mechanotransduction drives ageing by unleashing cGAS–STING signalling, a pillar of innate immunity, so sustaining YAP/TAZ mechanosignalling or inhibiting STING present promising approaches for limiting senescence-associated inflammation and improving healthy ageing.
Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04903-x The cryo-electron microscopy structure of the membrane-embedded ubiquitin ligase complex reveals its function as a retrotranslocation channel for shuttling mobile receptors out of peroxisomes.
Nature, Published online: 29 June 2022; doi:10.1038/s41586-022-04790-2 Cryo-electron microscopy structures of Drosophila Dicer-2–R2D2 complexes with and without small interfering RNA reveal how the RNA is presented to Argonaute in the correct orientation for viral gene silencing.
Nature, Published online: 29 June 2022; doi:10.1038/d41586-022-01732-w A simple method for incorporating molecules into the gaps of stacked semimetallic materials through immersion offers an efficient way of filtering electrons, which could be useful for information-storage technologies.
Nature, Published online: 29 June 2022; doi:10.1038/d41586-022-01551-z We charted the genetic history of the grey wolf over the past 100,000 years by analysing 72 ancient genomes. Placing dogs into this history, we found that they derive ancestry from at least two separate wolf populations.
Nature, Published online: 29 June 2022; doi:10.1038/d41586-022-01731-x The discovery that gut viruses can be transmitted from mouse pups to their mothers in saliva during breastfeeding reveals previously unrecognized sites of viral replication and means of viral transmission.
Meta-owned Facebook is removing status updates that discuss mailing abortion pills, and has even issued temporary bans to people who tried to post such content, Vice has confirmed . "I will mail abortion pills to any one of you. Just message me," read a status update by one user, who published the post on the day that Roe vs. Wade — the landmark Supreme Court case that legalized abortion in Ameri
Dogs genetically most similar to ancient Siberian wolves, but they are not direct ancestors and plenty of questions remain The tale of how grey wolves became the pet dog of today has received a new twist, with research suggesting our furry companions arose not just from one population of wild ancestors, but two. Dogs were the first animals to be domesticated by humans, an event thought to have ha
Medicare could waste up to $605 million per year on the controversial Alzheimer's drug aducanumab if it is eventually approved for widespread use because it is supplied in vials containing fixed doses that may not be appropriate for all patients — resulting in the trashing of large volumes of unused drug.
Researchers at Kanazawa University report in Biophysics and Physicobiology how to optimize high-speed atomic force microscopy experiments on live cell membranes, so that moving objects like molecules can be properly followed from frame to frame.
At the base of a winding staircase and tucked away in a dimly lit room, about a hundred healthy fish represent the last, best hope for an ancient species on the brink of extinction.
Researchers at Kanazawa University report in Biophysics and Physicobiology how to optimize high-speed atomic force microscopy experiments on live cell membranes, so that moving objects like molecules can be properly followed from frame to frame.
At the base of a winding staircase and tucked away in a dimly lit room, about a hundred healthy fish represent the last, best hope for an ancient species on the brink of extinction.
Bletilla Rchb. f. (Orchidaceae) is a small genus with great economic value distributed in Asia, and China is the distribution center of Bletilla with four species. The dried pseudobulb of B. striata was recorded as BaiJi, and was first recorded in Shennong's Classic of Materia Medica. Nevertheless, a systemic evaluation of the germplasm quality of Bletilla plants in China is absent.
The recent Fagradalsfjall eruption in the southwest of Iceland has enthralled the whole world, including nature lovers and scientists alike. The eruption was especially important as it provided geologists with a unique opportunity to study magmas that were accumulated in a deep crustal magma reservoir but ultimately derived from the Earth's mantle (below 20 km).
Berkeley engineers have created a new type of semiconductor laser that accomplishes an elusive goal in the field of optics: the ability to maintain a single mode of emitted light while maintaining the ability to scale up in size and power. It is an achievement that means size does not have to come at the expense of coherence, enabling lasers to be more powerful and to cover longer distances for ma
Fruit flies are known for their sweet tooth, but new research also indicates they may offer hints to how animals sense—and avoid—high concentrations of salt.
An international group of geneticists and archaeologists, led by the Francis Crick Institute, have found that the ancestry of dogs can be traced to at least two populations of ancient wolves. The work moves us a step closer to uncovering the mystery of where dogs underwent domestication, one of the biggest unanswered questions about human prehistory.
When heat waves hit, they don't just take a toll on people—the plants we depend on for food suffer too. That's because when temperatures get too high, certain plant defenses don't work as well, leaving them more susceptible to attacks from pathogens and insect pests.
A dramatic outbreak of kelp-eating sea urchins along the Central Coast of California in 2014, leading to a significant reduction in the region's kelp forests, was driven primarily by the emergence of sea urchins from their hiding places rather than an increase in the urchin population. In subsequent years, sea urchin movements enabled kelp forest recovery at sites that had been denuded "urchin bar
Bletilla Rchb. f. (Orchidaceae) is a small genus with great economic value distributed in Asia, and China is the distribution center of Bletilla with four species. The dried pseudobulb of B. striata was recorded as BaiJi, and was first recorded in Shennong's Classic of Materia Medica. Nevertheless, a systemic evaluation of the germplasm quality of Bletilla plants in China is absent.
Fruit flies are known for their sweet tooth, but new research also indicates they may offer hints to how animals sense—and avoid—high concentrations of salt.
An international group of geneticists and archaeologists, led by the Francis Crick Institute, have found that the ancestry of dogs can be traced to at least two populations of ancient wolves. The work moves us a step closer to uncovering the mystery of where dogs underwent domestication, one of the biggest unanswered questions about human prehistory.
When heat waves hit, they don't just take a toll on people—the plants we depend on for food suffer too. That's because when temperatures get too high, certain plant defenses don't work as well, leaving them more susceptible to attacks from pathogens and insect pests.
A dramatic outbreak of kelp-eating sea urchins along the Central Coast of California in 2014, leading to a significant reduction in the region's kelp forests, was driven primarily by the emergence of sea urchins from their hiding places rather than an increase in the urchin population. In subsequent years, sea urchin movements enabled kelp forest recovery at sites that had been denuded "urchin bar
From nourishing our foods to storing massive amounts of carbon, soil is teeming with diverse microbial life that could slow global warming. Climate change scientist Jane Zelikova calls for agricultural practices that protect Earth's soil by growing climate-adapted crops that don't mess with the microbes. "Soils are the literal foundation of life on this planet — the reason that we eat and the cli
Composting plants process biowaste into finished compost, which ends up as fertilizer in soils. A study by the University of Bayreuth shows that finished compost from composting plants in Germany contains a large number of biodegradable plastic particles. Applicable legal and certification standards are not violated by the sizes and quantities of the particles detected. However, the data published
Whether we've got the flu or have had too much to drink, most of us have experienced nausea. Unlike other universal sensations such as hunger and thirst, however, scientists still don't understand the biology behind the feeling—or how to stop it. A new study in mice identifies a possible key player: specialized brain cells that communicate with the gut to turn off the feeling of nausea. It's an "
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31563-2 Insulin sensitivity declines with age via unclear mechanisms. Here, the authors show that the activity of membrane type 1 matrix metalloproteinase (MT1-MMP) is increased with ageing, leading to cleavage of the insulin receptor, and show that metabolic effects can be rescued by MT1-MMP inhibition in mice.
Det mesta av köttet från djur tas om hand, men inom fiskeindustrin har fokus legat på filéerna – ett synsätt som går stick i stäv med hållbarhet och svensk livsmedelsstrategi. Forskare vid Chalmers har nu tagit fram en ny teknik som tar vara på fiskens alla näringsrika delar. Inlägget dök först upp på forskning.se .
Kotkompressioner är mycket vanliga bland äldre, och risken att drabbas av nya frakturer är stor. En avhandling från Göteborgs universitet slår fast att nya rutiner för röntgen borde införas för bättre diagnostik och läkemedelsbehandling. Inlägget dök först upp på forskning.se .
Andelen kommunpolitiker med svaga band till arbetsmarknaden och kärnfamiljen är betydligt högre hos Sverigedemokraterna än hos övriga partier i Sverige. Det visar en studie från Stockholms universitet. Inlägget dök först upp på forskning.se .
Yesterday Cassidy Hutchinson, a former aide to White House Chief of Staff Mark Meadows, told the House's January 6 committee that Donald Trump knew rioters were armed, and urged them to go to the Capitol anyway. But the most surprising element of her testimony was her claim that Trump lunged for the steering wheel of his armored limousine and tried to force his Secret Service detail to take him t
CABI has confirmed a new species of fungus after the BBC Springwatch show called on Dr. Harry Evans' expertise when the mysterious specimen was first discovered in a Victorian gunpowder store at Castle Espie wetland center in Northern Ireland.
Americans are more forgiving of lies when they come from politicians in their own party, research finds. In five new studies, researchers examined how conservative and liberal Americans responded to media reports of politicians' falsehoods. Even accounting for partisan biases in how much people dismissed the reports as fake news and assumed the lies were unintentional, the studies consistently id
Scientists report that apratoxin S4, an anticancer drug candidate that targets a human protein, can interfere with the replication of many viruses, including SARS-CoV-2 and influenza A, offering a possible pan-viral therapy.
Researchers have shown that tiny, robust immune particles derived from the blood of a llama could provide strong protection against every COVID-19 variant including Omicron and 18 similar viruses.
CABI has confirmed a new species of fungus after the BBC Springwatch show called on Dr. Harry Evans' expertise when the mysterious specimen was first discovered in a Victorian gunpowder store at Castle Espie wetland center in Northern Ireland.
Scientists know that Europeans brought red foxes to North America, likely for hunting, while other red foxes escaped into the wild from fur farms. But are some red foxes found on the East Coast, and in North Carolina, native?
Scientists know that Europeans brought red foxes to North America, likely for hunting, while other red foxes escaped into the wild from fur farms. But are some red foxes found on the East Coast, and in North Carolina, native?
The development of an embryo is a well-orchestrated string of processes, ensuring correct formation and positioning of vital organs of the growing organism. At the molecular level, these processes are controlled in a precise manner by switching on or off specific factors such as genes or proteins. Any errors in these processes could result in physical defects or disease in the newborn organism.
Sitting in a semi-circle in the yard outside of a village school in Nepal, a group of farmers share their concerns about the future. They discuss how the rain is unreliable—droughts and floods are both becoming more common. The heat is overwhelming before the rains come.
The development of an embryo is a well-orchestrated string of processes, ensuring correct formation and positioning of vital organs of the growing organism. At the molecular level, these processes are controlled in a precise manner by switching on or off specific factors such as genes or proteins. Any errors in these processes could result in physical defects or disease in the newborn organism.
Sitting in a semi-circle in the yard outside of a village school in Nepal, a group of farmers share their concerns about the future. They discuss how the rain is unreliable—droughts and floods are both becoming more common. The heat is overwhelming before the rains come.
Someday, a swarm of cellphone-size robots could whisk through the water beneath the miles-thick icy shell of Jupiter's moon Europa or Saturn's moon Enceladus, looking for signs of alien life. Packed inside a narrow ice-melting probe that would tunnel through the frozen crust, the tiny robots would be released underwater, swimming far from their mothercraft to take the measure of a new world.
With its Green Deal, the European Union has set itself much-needed ambitious climate goals. But the energy crisis and geopolitical tensions are making these difficult to achieve. Seven researchers from the Leiden-Delft-Erasmus Universities (LDE) alliance have written a white paper offering solutions.
Nigeria—the sixth largest producer of cashew nuts globally—exports more than 80% of its raw cashews primarily to Vietman and India where they are processed into various consumer products such as butter, food and cosmetic ingredients.
A little under a year ago, the world's biggest direct air capture (DAC) plant got up and running in Iceland. Christened Orca after the Icelandic word for energy, the plant was built by Swiss company Climeworks in partnership with Icelandic carbon storage firm Carbfix . Orca can capture about 4,000 tons of carbon per year (for scale, that's equal to the annual emissions of 790 cars). Now Climework
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This is today's edition of The Download , our weekday newsletter that provides a daily dose of what's going on in the world of technology. Introducing: Our TR35 list of innovators for 2022 Spoiler alert: our annual Innovators Under 35 list isn't actually about what a small group of smart young people have been up to (although that's certainly part of it.) It's really about where the world of tech
Don Mattes started giving to the Picower Institute for Learning and Memory at MIT before he himself was diagnosed with Alzheimer's disease. Since his death in 2020, his wife, Glenda, has carried forward Don's passion for its work. "My wish is that no one ever has to go through the horrors of Alzheimer's disease ever again," Glenda says. The Matteses have also supported the Koch Institute for Inte
Lisa Burton O'Toole, SM '09, PhD '13, was born on a cattle farm outside of Fort Worth, Texas, the daughter of a horseshoer and an administrative assistant. Raised by a single mom who had three jobs and urged her two daughters to reach for the stars, she grew up determined to work hard to land a great job. A data scientist and small-business founder who is now a vice president at HearstLab, she ev
All too often, the work of developing global disaster and climate resiliency happens when disaster—such as a hurricane, earthquake, or tsunami—has already ravaged entire cities and torn communities apart. But Elizabeth Petheo, MBA '14, says that recently her work has been focused on preparedness. It's hard to get attention for preparedness efforts, explains Petheo, a principal at Miyamoto Interna
Especially for people of color, the road to MIT often begins with advice and encouragement from a teacher or guidance counselor. That was the case for Michael Dixon '88, who grew up on the South Side of Chicago. He'd long been interested in outer space, reading science texts and science fiction as well as watching PBS's Nova series on WTTW, Chicago's public television station. However, the idea t
"My focus has always been on social change," says Steven Lewis Yaffee, PhD '79, a professor of natural resources and environmental policy at the University of Michigan. "On training practitioners to go out and effect change in the real world." Yaffee caught the eco bug in middle school in Maryland when he read Rachel Carson's now seminal book Silent Spring. At the University of Michigan, he studi
Joseph "Pepe" Fields '67 has an MIT degree in chemistry, but he's spent his career working all over the world in international management. And recently, he's been driving a recreational vehicle around the US to build affordable housing with a Habitat for Humanity program called RV Care-A-Vanners. RV owners who join the program drive to where they're needed and work as volunteer builders, construc
On July 1, Stephen D. Baker '84, MArch '88, begins his one-year term as president of the MIT Alumni Association, succeeding Annalisa Weigel '94, '95, SM '00, PhD '02. Baker's long history with MIT began with bachelor's and master's degrees in architecture. He is currently president and senior principal of BWA Architecture, a 27-person firm he cofounded in Boston in 1994 with Margaret (Garet) Wohl
On March 23, 1912, the very day the subway connecting Boston and Cambridge opened to the public, another event took place that would change Kendall Square even more profoundly than the new, state-of-the-art transit system. As fate would have it, that was the day when a large swath of property adjacent to the square was formally conveyed to MIT, paving the way for the school's move across the rive
Secreted beneath MIT's Killian Court and accessible only through a subterranean labyrinth of tunnels, a clandestine lab conducts boundary-pushing research, fed by money siphoned from a Department of Defense grant. In these shadowed, high-tech halls, astrophysicist and astronaut Valentina Resnick-Baker, who is experiencing strange phenomena after an encounter with a planet-threatening asteroid, di
Nigeria—the sixth largest producer of cashew nuts globally—exports more than 80% of its raw cashews primarily to Vietman and India where they are processed into various consumer products such as butter, food and cosmetic ingredients.
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31327-y Unbiased screen of random sequences identified many short IRES-like elements to drive circular RNA translation and hundreds of rolling circle translation events, suggesting a pervasive cap-independent translation in human transcriptome.
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31301-8 The reasons why malaria manifests with a variety of well-recognized clinical phenotypes remain poorly understood. Here, using distinct rodent models, the authors reveal that the microbiota colonizing the lung promotes respiratory distress syndrome and mortality during malaria infections.
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31495-x The impact of prior infection on the immune response to COVID-19 vaccination has not been fully characterised. Here, the authors use data from ~100,000 adults in the UK and find that a single vaccine dose in those with prior infection produces a comparable or stronger response to two doses in those without infec
PLUS. Aftalen vil ikke gavne godstransporten på jernbanen og kan endda ende med at øge konkurrencefordelen for godstransport på vejene, vurderer Ole Kien fra IDA Rail.
Sign up for The Weekly Planet, Robinson Meyer's newsletter about living through climate change, here. In February, Bank of America offered its employees a notable perk: If they had worked at the bank for at least three years, and made less than $250,000, then it would give them $4,000 to buy a new electric car. (Employees interested in merely leasing an EV could claim $2,000.) The move, attached
NASA's Double Asteroid Redirection Test (DART) mission is the world's first full-scale planetary defense test against potential asteroid impacts on Earth. Researchers of the University of Bern and the National Center of Competence in Research (NCCR) PlanetS now show that instead of leaving behind a relatively small crater, the impact of the DART spacecraft on its target could leave the asteroid ne
Nature, Published online: 29 June 2022; doi:10.1038/d41586-022-01742-8 Personalized treatments and large population studies in China are helping to uncover patterns for a range of conditions, from autism to hereditary hearing loss.
Ceramides are a type of lipid that are found in abundance in the top layer of the skin, called the stratum corneum. They play a crucial role in the skin's barrier function, preventing entrance of pathogens and allergens and the loss of water and electrolytes. Mutations in the genes involved in the production of ceramides lead to a wide range of skin diseases.
In a new report now published in Science Advances, Zongyao Zhou and a team of scientists in chemical engineering and physical science and engineering at the King Abdullah University of Science and Technology in Saudi Arabia developed an artificial light-gated ion channel membrane using conjugated microporous polymers. The team was inspired by light-gated ion channels in cell membranes that play an
Ceramides are a type of lipid that are found in abundance in the top layer of the skin, called the stratum corneum. They play a crucial role in the skin's barrier function, preventing entrance of pathogens and allergens and the loss of water and electrolytes. Mutations in the genes involved in the production of ceramides lead to a wide range of skin diseases.
Ph.d.-studerende Trine Strandgaard fra Institut for Klinisk Medicin på Aarhus Universitet har netop modtaget Fogh-Nielsen-legatet, der gives til talentfulde forskere, som bedriver fremragende forskning.
UNSW chemists have engineered a new molecular "vice," by including the rare metal osmium, that can bind methane for hours—providing crucial evidence for an intermediate step that will inform new catalysts to store, transport, or transform the gas into methanol and help to avert wastage of the gas worldwide.
Will artificial intelligence be a help or a hindrance in the response to climate change? It depends. In the journal Nature Climate Change , a team of experts in AI, climate change, and public policy present a framework for understanding the complex and multifaceted relationship of AI with greenhouse gas emissions and suggest ways to better align AI with climate change goals. "AI affects the clima
The Smithsonian's National Portrait Gallery and The Atlantic announce a new, multi-platform collaboration titled " Perspectives: The Atlantic 's Writers at the National Portrait Gallery ." As part of the reinstallation of the museum's permanent-collection galleries, the Portrait Gallery and The Atlantic will highlight a selection of the country's founding voices in literature, politics, philosoph
The Himalayas and neighboring mountain ranges (or High Mountain Asia), the planet's most extensive icy systems outside the polar regions, have the world's largest undeveloped hydropower potential and are seeing numerous dams and reservoirs under construction or planning. However, climate change is destabilizing the landscapes and threatening numerous hydropower projects according to a new study le
Recent survey results link acceptance of gene-edited foods with a belief that science and technology are ways to solve society's problems. Through CRISPR and other gene-editing technologies, researchers and developers are poised to bring dozens—if not hundreds—of new products to grocery stores: mushrooms with longer shelf lives, drought-resistant corn, and bananas impervious to a fungus threateni
Using NASA's Swift spacecraft, astronomers have discovered a new cataclysmic variable (CV) through its ultraviolet (UV) bursting activity. The newfound CV, designated TUVO-21acq, was detected as part of the Transient UV Objects Project (TUVO). The finding is reported in a paper published June 21 on arXiv.org.
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31504-z Understanding CD8 + T cell response to immune checkpoint blockade at the molecular level is important for the design of more efficient cancer immune therapies. Authors show here that the histone lysine methyltransferase Suv39h1 controls the transcriptional programs that determine the functionality of CD8 + T cel
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31415-z Cancer develops in Wiskott-Aldrich syndrome (WAS). Here the authors identify a role for WAS-protein (WASp) in the DNA stress-resolution pathway by promoting the function of Replication Protein A at replication forks after DNA damage.
A team of researchers from the City University of Hong Kong, working with several colleagues from the U.K., has modified an AI application for use in detecting chick distress calls in noisy environments. In their paper published in Journal of the Royal Society Interface, the group describes the modifications they made to a commercially available AI application and how well it worked when tested on
Human saliva may contain an enzyme which can decompose the plastic polyethylene terephthalate (PET). Researchers found the promising enzyme, a hydrolase, in a database containing human metagenome samples. As they report in the journal Angewandte Chemie International Edition, this newly discovered hydrolase performs better than many other known bacterial PET hydrolases. It can be produced using bio
On the 50th anniversary of the discovery of a close connection between star formation in galaxies and their infrared and radio radiation, researchers at the Leibniz Institute for Astrophysics Potsdam (AIP) have now deciphered the underlying physics. To this end, they used novel computer simulations of galaxy formation with a complete modeling of cosmic rays.
A team of researchers from the City University of Hong Kong, working with several colleagues from the U.K., has modified an AI application for use in detecting chick distress calls in noisy environments. In their paper published in Journal of the Royal Society Interface, the group describes the modifications they made to a commercially available AI application and how well it worked when tested on
The production of wild and farm-raised fish, shellfish and algae reached record levels in 2020, and future increases could be vital to fighting world hunger, the Food and Agriculture Organization said Wednesday.
Human saliva may contain an enzyme which can decompose the plastic polyethylene terephthalate (PET). Researchers found the promising enzyme, a hydrolase, in a database containing human metagenome samples. As they report in the journal Angewandte Chemie International Edition, this newly discovered hydrolase performs better than many other known bacterial PET hydrolases. It can be produced using bio
The production of wild and farm-raised fish, shellfish and algae reached record levels in 2020, and future increases could be vital to fighting world hunger, the Food and Agriculture Organization said Wednesday.
A team of researchers at the University of New Brunswick has conducted an experiment to learn more about the evolution of cooperation in groups of living creatures. In their paper published in the journal Biology Letters, the group describe genetically altering a type of green algae to allow it to bypass cooperation.
A team of researchers at the University of New Brunswick has conducted an experiment to learn more about the evolution of cooperation in groups of living creatures. In their paper published in the journal Biology Letters, the group describe genetically altering a type of green algae to allow it to bypass cooperation.
En spritny udgave af avisen Techie, der skal inspirere børn til at interessere sig for teknologi og naturvidenskab, er klar fra trykken. Avisen er udgivet af Teknologiens Mediehus i samarbejde med Teknologipagten og kommer i år med ud til alle Ingeniørens abonnenter.
Fra 1. juli 2022 kan almen praksis henvise patienter med vage symptomer direkte til en række billeddiagnostiske undersøgelser, selvom patienten ikke opfylder kriterierne til en kræftpakke. Den nye aftale står regionerne bag, og den vækker begejstring i Dansk Selskab for Almen Medicin.
Two weeks ago, retired Marine General John Allen resigned as the head of the prestigious Washington think tank the Brookings Institution, following revelations of what federal prosecutors allege was his unregistered lobbying for the government of Qatar. I briefly worked with Allen in the Obama administration, and his record of public service is lengthy and admirable. But after reading through bot
The #paradigm #shift – or the #renovation of the #dualistic science building "Under the strong influence of natural science … we have got used to equating our perception of reality with reality and even to interpret this reality in terms of a materially founded reality that can be broken down into parts. However, modern physics has taught us an interesting lesson that has led to a profound corr
COVID infection has been associated with an increased risk of neurodegenerative and neurovascular disease – another reason to keep our eye on this serious illness. The post first appeared on Science-Based Medicine .
The MIT Morningside Academy for Design , an interdisciplinary center that aims to build on the Institute's leadership in design-focused education and become a global hub for design research, thinking, and entrepreneurship, will launch in September 2022, President L. Rafael Reif announced in March. The academy, which will be housed in the Metropolitan Warehouse with the School of Architecture and
MIT will be taking several new measures to support its Indigenous community and advance scholarship on the history of Native Americans and the Institute, President L. Rafael Reif announced in April. In the spring of 2021, the Institute launched 21H.283 (The Indigenous History of MIT), a class that explores the ways MIT's history intersects with the history of oppression Native Americans have face
Across much of the industrialized world, with notable exceptions , everyday life has returned to some semblance of pre-pandemic normalcy. Travel restrictions have largely been lifted. In the West at least, masks have mostly disappeared from shops and public transport. Restaurants, theaters, museums, sports stadiums, and concert halls are once again brimming with locals and tourists alike. But one
Der er ventetid på at blive behandlet for svær migræne i Danmark, og i mellemtiden betaler folk af egen lomme for ikke-farmakologiske ikke-evidensbaserede behandlinger. Ifølge overlæge bør vi overveje at åbne op for, at personer med migræne selv kan betale for den behandling, som virker.
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31407-z How the thalamus and the cortex interact in the context of perception remains largely unclear. Here, the authors show that rhythmic activity in the human mediodorsal thalamus and prefrontal cortex interact to predict whether a near-threshold visual stimulus will be seen, contradicting the traditional view that t
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-30795-6 This study presents seismic images across the central Tianshan. The results show that Tianshan's crust was extensively deformed according to its inherited properties, but was limitedly underthrusted by surrounding blocks
(Photo: Ildar Garifullin/Unsplash) It can't be overstated: buying a car is ridiculously complicated. Between deceptive advertising, sleazy sales tactics, and confusing fees, most Americans rank buying their next ride as more stressful than getting married. Vehicle prices have also skyrocketed since the start of the COVID-19 pandemic, resulting in an extra layer of financial anxiety. The Federal T
Nature, Published online: 29 June 2022; doi:10.1038/d41586-022-01792-y Scientists in Thailand have established that a tabby passed SARS-CoV-2 to a veterinary surgeon — although such cases of cat-to-human transmission are probably rare.
Guest commentary from Paul Bates, Peter Bauer, Tim Palmer, Julia Slingo , Graeme Stephens, Bjorn Stevens, Thomas Stocker and Georg Teutsch Gavin Schmidt claims that the benefits of k-scale climate models (i.e. global climate models with grid spacing on the order of 1 km) have been "potentially somewhat oversold" in two recent Nature Climate Change papers. By this, we suppose Gavin means that the
Frank, warm and funny podcaster and campaigner who raised millions for bowel cancer charities In the last five years of her life, Deborah James, who has died aged 40 from cancer, never stopped talking about life as worth living. She did this as co-host of BBC Radio 5 Live's award-winning, lively podcast about living with cancer, You, Me and the Big C, originally alongside the broadcast journalist
The author of a 2021 paper in a computer science journal has lost the article because he purportedly stole the text from the thesis of a student in Pakistan – a charge he denies. According to the editors of Computational Intelligence and Neuroscience, a Hindawi title, Marwan Ali Albahar, of Umm Al Qura University College … Continue reading
We'll have to wait a little longer to find out what's up with one of the most interesting asteroids in the solar system. NASA has confirmed that a minor software glitch will cause a delay for its upcoming Psyche mission, which was set to launch in September 2022. The motion of the planets is working against NASA here, so even a small delay means Psyche won't be able to launch in 2022 at all, and
There are still parts of Philadelphia's SEPTA transportation system that accept tokens. But today, in nearly every major American city, you'll see transit riders tapping their way onto buses and subway platforms using their phones. The shift has been swift. Like so many things consumers brushed off as needlessly complicated before the pandemic—QR codes, order pickup at retail stores, grocery deli
In February, the city of Toronto announced plans for a new development along its waterfront. They read like a wish list for any passionate urbanist: 800 affordable apartments, a two-acre forest, a rooftop farm, a new arts venue focused on indigenous culture, and a pledge to be zero-carbon. The idea of an affordable, off-the-grid Eden in the heart of the city sounds great. But there was an entirel
Feature image by Eric Kilby, CC BY-SA 2.0 Last week, the PCI-SIG working group that controls the PCI Express standard announced that it was on track to finalize and release the PCIe 7.0 standard by 2025. The amount of time between finalization and commercialization varies, but is typically 12-18 months. We might reasonably expect PCIe 7.0 devices in-market by 2026-2028, with support for up to 512
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31272-w The processing of nociception in the somatosensory cortex (S1) has yet to be fully understood. Here, the authors demonstrate that the dysgranular region in S1 has an affinity for nociception and is critically involved in pain-like behavior.
Nature, Published online: 29 June 2022; doi:10.1038/d41586-022-01735-7 Drugs made from antibodies are huge money-makers for some conditions — but they have gained little traction in infectious diseases, including COVID.
In 2015, Brooklyn resident Shabazz Stuart regularly biked to his job at a local business improvement district. Then his bicycle was stolen—the third case of two-wheeled larceny he'd experienced in five years. The theft sent him back to mass transit while he saved up money to buy a replacement. It also put him on a new career path. Paying hundreds or thousands of dollars to replace a bike can be a
One evening last summer, my family was enjoying a picnic in the park near our house in London when two dogs attacked our blind 15-year-old Jack Russell terrier, Zoey. They pounced on her, locking their jaws. As my husband threw himself on the dogs, I begged the owner to intervene. He refused—until he realized I was calling the police. Only then did he restrain his animals, one of which had starte
I tibetanske gletsjere har kinesiske forskere fundet næsten 1.000 bakteriearter fra prøver af sne og is. De frygter, at der, i takt med gletsjerne smelter, vil blive spredt sygdomme.
Sound waves have been used to build complex structures in mid-air out of floating components and droplets of glue, showing the approach may have engineering and medical applications
Scientific Reports, Published online: 29 June 2022; doi:10.1038/s41598-022-14991-4 Effect of distributed Bragg reflectors on photoluminescence properties of CH 3 NH 3 PbI 3 film
Barnonkologen Kees-Jan Pronk forskar om vad som händer i blodet hos barn som utvecklar leukemi. Han forskar också på biverkningarna av de tunga behandlingar som många barn med leukemi genomgår.
Researchers found dozens of incidents where birds fell to the ground after being electrocuted on power lines, and sparked fires. They also proposed steps to prevent such incidents.
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31358-5 Recent studies proposed that m6A modification in mammalian mRNAs increases their recruitment to stress granule. However, here the authors observed that m6A modification has a limited effect on mRNA entry into stress granules.
Det lykkedes ikke for Region Sjælland at lokke praktiserende læger til hverken Horslunde eller Rødby. Derfor skal de to lægehuse drives som udbudsklinikker.
Although only recently recognized as an issue in wildlife ecology, snake fungal disease (SFD) is of emerging concern in the U.S., with parallels among other better-known wildlife fungal diseases such as white-nose syndrome in bats. SFD can be deadly to snakes, and even in milder cases disrupts an animal's abilities to perform normal biological functions such as hibernation, eating and avoiding pre
Although only recently recognized as an issue in wildlife ecology, snake fungal disease (SFD) is of emerging concern in the U.S., with parallels among other better-known wildlife fungal diseases such as white-nose syndrome in bats. SFD can be deadly to snakes, and even in milder cases disrupts an animal's abilities to perform normal biological functions such as hibernation, eating and avoiding pre
This month: Twenty-six years after the end of the Bosnian War, farmers in Livno are once again making cheese the traditional way, grazing herds of sheep on the wide-open plains. The animals' return is restoring natural wetlands, leading to cascading impacts on the environment and the economy.
Researchers at UC Santa Cruz have identified specific elements of tone and style in online speech that are linked to hyperpartisan echo chambers. The findings are now published in the journal Discourse & Society.
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31189-4 Nonradiative Auger recombination and poor stability of colloidal-quantum-dot solids at high current densities are primary obstacles to the realization of laser diodes based on these materials. Jung et al. achieve the current densities in excess of 1,000 A cm−2, which allows them to boost brightness to ~10 millio
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31399-w Activating mutations of BRAF alone are inadequate to drive melanoma formation. Here the authors show that activation of Hippo signalling by oncogenic BRAF represents an additional safeguard to limit BRAF-dependent human melanocyte growth and melanoma formation.
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31500-3 Overproduction of efflux pumps represents an important mechanism of Klebsiella pneumonia resistance to tigecycline. Here, the authors design TPGS- and S-thanatin functionalized nanorods loaded with tigecycline to increase drug accumulation inside bacteria and overcome bacterial resistance.
Nature Communications, Published online: 29 June 2022; doi:10.1038/s41467-022-31093-x Most machine-learning force fields dismiss long-range interactions. Here the authors demonstrate the BIGDML approach for building materials' potential energy surfaces that enables a broad range of materials simulations within accuracies better than 1 meV/atom using just 10–200 structures for training.
Im getting this test done tomorrow, what can I expect? They said I will be radioactive. Whatever that means. Anyone have this procedure done? submitted by /u/Reasonable-Future914 [link] [comments]
The Department of Health and Human Services will make 296,000 doses available in the coming weeks, and expects a total of 1.6 million doses to be available in the U.S. by the end of the year. (Image credit: Cynthia S. Goldsmith, Russell Regner/CDC via AP)
It has long been known that when salt is kept in a humid environment, it absorbs water, dissolving some of the salt and making it clump. Now, researchers from Japan have discovered that water vapor isn't the only agent that can do this.
Australian paleontologists from Flinders University have described a new genus of giant fossil kangaroo from the mountains of central Papua New Guinea.
Australian paleontologists from Flinders University have described a new genus of giant fossil kangaroo from the mountains of central Papua New Guinea.
Chickens make more sounds than most of us realize. They cluck when content, squawk when frightened, and sing "buk, buk, ba-gawk" when laying an egg. Their chicks vocalize too, and they can vary that simple sound to signal pleasure or distress. Now, scientists have developed an artificial intelligence (AI) program that automatically identifies these SOS calls, an advance that could help farmers sa
The technology correctly distinguished distress calls from other barn noises with 97% accuracy Artificial intelligence that could improve the welfare of farmed chickens by eavesdropping on their squawks could become available within five years, researchers say. The technology, which detects and quantifies distress calls made by chickens housed in huge indoor sheds, correctly distinguished distres
Of all the eyeballs in Glen Jeffery's office, only a very small minority are his. "Oh, I've got an office full of eyes," Jeffery, a neuroscientist at University College London, told me. Over Skype, he fished one of his favorites out of an opaque vial: About the size of a golf ball and fringed with white tissue, it looked a bit like a poached egg with a slate-hued yolk. The prized specimen was a r
While examining eight-year-old data from NASA's Curiosity Mars rover, scientists have made a tantalizing new discovery: the "total organic carbon," a key ingredient of life, is surprisingly high in the Martian rocks the rover was scanning. While the organic carbon may have originated from non-living sources, including meteorites and volcanoes, the discovery does lend modest new support to the the
New research led by the University of East Anglia (UEA) quantifies the benefits of limiting global warming to 1.5 degrees Celsius and identifies the hotspot regions for climate change risk in the future.
It has been 3 months since the United Kingdom reported severe, unexplained hepatitis was sending young children to hospitals in unusual numbers. The initial handful of cases reported in Scotland on 31 March were soon joined by dozens and then hundreds, primarily from Europe, the United States, and the United Kingdom. As of 22 June, the global total, from 33 countries, has swollen to 920 probable
In one sense, this is how it was always supposed to go: When viruses evolve, vaccines should follow, and sometimes try to leap ahead. The COVID-19 shots that the U.S. has used to inoculate hundreds of millions of people are simply so new that they've never had to undergo a metamorphosis; up until now, their original-recipe ingredients have stood up to SARS-CoV-2 well enough . But the virus they f
In the last few minutes of today's January 6 committee hearing, Representative Liz Cheney presented evidence of possible witness intimidation. Several witnesses, she reported , had received messages from shadowy persons purportedly close to former President Donald Trump that implicitly warned of consequences to follow if those witnesses told the truth about his conduct. That is one sort of attemp
This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. Sign up for it here . Here in the United States, Russia's atrocities against Ukraine have been pushed off the front pages by news about controversial Supreme Court decisions and some of the most shocking revelations from t
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