In the search for eternal youth, fecal transplants may seem like an unlikely way to reverse the aging process. However, scientists have provided evidence, from research in mice, that transplanting fecal microbiota from young into old mice can reverse hallmarks of aging in the gut, eyes, and brain. In the reverse experiment, microbes from aged mice induced inflammation in the brain of young recipie
Nature Communications, Published online: 04 May 2022; doi:10.1038/s41467-022-30069-1 It is not fully understood how behavioral flexibility is established in the context of automatic performance of a complex motor skill. Here the authors show that corticostriatal activity can flexibly transition between two modes during a reach to-grasp task in rats: reliable neural pattern generation for precise,
Chad Enzyme Scientists used machine learning to discover what they say could be a new way to speed up the process of breaking down plastic significantly, Vice reports . As detailed in a new paper published in the journal Nature , a research team from the University of Texas at Austin modified an enzyme to break down the individual components of polyethylene terephthalate (PET), a commonly used pl
Sign up for David's newsletter, The Third Rail, here. We do not know if Justice Samuel Alito's leaked draft majority opinion in Dobbs v. Jackson Women's Health represents the current consensus of a majority of the Supreme Court. We certainly don't know yet if it's a preview of the Court's actual ruling. Decisions are not final until opinions are issued, and dramatic history exists of a Supreme Co
You are no doubt viewing this article on a digital device whose basic unit of information is the bit, either 0 or 1. Scientists worldwide are racing to develop a new kind of computer based on the use of quantum bits, or qubits, which can simultaneously be 0 and 1 and could one day solve complex problems beyond any classical supercomputers.
Only 15 states require insurance to cover in vitro fertilization, a pricey path to parenthood. But expensive procedures and drugs can lead to unexpected bills even for the fortunate who are insured. (Image credit: Oona Tempest/Kaiser Health News)
NASA and the European Space Agency are gearing up to bring home a pristine sample of Martian rock. But given the small chance of life on the red planet, they have to grapple with safety questions. (Image credit: NASA/JPL-Caltech/MSSS)
In spite of being a fan of Dogecoin , SpaceX and Tesla CEO Elon Musk is a noted hater of NFTs . And now a characteristically cryptic Musk has changed his profile picture to what appears to be a stolen collage of Bored Ape NFTs, inviting drama with the infamously irascible NFT community . "I dunno… seems kinda fungible," Musk tweeted , in an apparent mockery of the tech. The image appears to have
Oops! After years of setbacks, Boeing is finally rolling out its Starliner spacecraft to the launchpad today for its second attempt to rendezvous with the International Space Station. Doing no favors for the spacecraft's reputation for jankiness , it ran into yet another mishap along the way. While strapped to the back of a large truck, a piece of the capsule's window appeared to pop off, tumblin
So Long Russian cosmonaut Alexander Skvortsov, whom Russian news outlet Moskovskii Komsomolets describes as the "hero of Russia," gave the outlet a short interview explaining his departure from the space program earlier this week. He says there wasn't enough to keep him busy on the International Space Station — and, pushing him over the edge, Skvortsov doesn't want to collaborate with the America
This past weekend, Anthony Fauci bailed on the White House Correspondents' Dinner. President Joe Biden's chief medical adviser concluded that the indoor event, though open only to vaccinated attendees who tested negative for COVID-19 the same day, was too risky for his own taste. Biden himself split the difference and showed up only for the speeches , not for the meal. Asked to explain this turn
I, as far as I can tell, have not yet been infected by the virus that causes COVID-19. Which, by official counts, makes me an oddball among Americans. Granted, I could be wrong. I've never had a known exposure or symptoms, but contact tracing in the United States is crummy and plenty of infections are silent. I've taken many coronavirus tests, but not that many coronavirus tests, and it's always
"The main thing is to keep the main thing the main thing." This was the advice that Haley Barbour, the Republican National Committee chair, former governor, and onetime presidential candidate, liked to give to colleagues. It's easy to say, but hard to do. Look at Governor Ron DeSantis in Florida. His main thing should be delivering a strong economy and keeping schools open. Instead, he's let the
Long ago, before J. D. Vance started doing his best to sound like every other MAGA candidate in the country, he had an ear for a metaphor. Reflecting on how heroin and prescription opioids had ravaged his home state of Ohio, Vance worried that a certain Republican candidate for president would have a similar effect. "[Donald] Trump is cultural heroin. He makes some feel better for a bit. But he c
In November 2020, the Republican Derrick Van Orden narrowly lost his attempt to unseat Representative Ron Kind in Wisconsin's Third District, falling just 10,000 votes behind the veteran Democrat out of nearly 400,000 cast. But Van Orden insisted that voter fraud had tainted the election results. Two months later, the former Navy SEAL was in Washington, D.C., on January 6, "to stand for the integ
Studies of ischaemic stroke patients open up possibility of treatments to prevent condition and improve recovery Scientists have identified specific groups of gut microbes that could increase or decrease someone's risk of suffering the most common type of stroke. The research, presented at the European Stroke Organisation Conference (ESOC) in Lyon, France, adds to growing evidence that alteration
Twenty-two states have abortion bans that would become law almost immediately if a leaked Supreme Court decision on abortion rights goes into effect. Many of these state bans contain no exceptions for rape or incest survivors. Not so long ago, such exceptions were regularly included in proposed abortion bans, in part because they're popular: For decades, about 75 percent of Americans have consist
Cambridge scientists say robot is capable of 'tasting' and checking whether balance of flavours is right The culinary robots are here. Not only to distinguish between food which tastes good and which doesn't, but also to become better cooks. A robot chef designed by researchers at Cambridge University has been trained to taste a dish's saltiness and the myriad of ingredients at different stages o
Winlaton Mill, Gateshead: The landscape here is vast and exhilarating, but a close look reveals a curious plant with a link to the area's coal past When the 12th Earl of Strathmore, a 19th-century nimby who made an immense fortune from coal, refused to allow trains across his Gibside estate , the North Eastern Railway adopted an expensive alternative route via four viaducts and a cutting. After t
This fascinating, touching look at phalloplasty (and the ways having an arm-penis can make life tricky) has many moments of levity – and thankfully a happy ending If, when you saw the title of this documentary, The Man With a Penis on His Arm (Channel 4), your first thought was: "Wait – like the mouse with the ear on its back? But a man and a penis and an arm?" the answer is ineluctably: yes. Jus
Sign up for The Weekly Planet, Robinson Meyer's newsletter about living through climate change, here. For the past few days, a heat wave of mind-boggling scale and intensity has gripped South Asia. More than 1 billion people in India and Pakistan have endured daytime highs of 40 degrees Celsius, or 104 degrees Fahrenheit. Delhi, the world's second-largest city, has suffered through back-to-back d
An international team of astronomers has detected a new kilonova associated with a nearby gamma-ray burst (GRB) known as GRB 211211A. The finding, reported in a paper published April 22 on arXiv.org, could improve our understanding about the origin and nature of the still mysterious GRBs.
NASA's Mars Perseverance rover has been bagging up dirt and rocks in hopes that a future mission to the Red Planet will stop by, scoop them up, and bring them back to Earth for further study. But returning space rocks from an alien planet comes with inherent risks, NPR reports , potentially allowing dangerous microbes to come along for the ride. That's a huge if — despite our best efforts, we hav
Space Ride Charming footage from from the interior of the International Space Station shows what happens to the astronauts inside when the ship fires its thrusters. That's cool on its own, but it's also a terrific demonstration of Newtonian physics. Case in point, instead of the astronauts moving inside the ISS, the video that the European Space Agency posted to YouTube shows the ISS moving while
The pig heart transplanted into an American patient earlier this year in a landmark operation carried a porcine virus that may have derailed the experiment and contributed to his death two months later, say transplant specialists. David Bennett Sr. was near death in January when he received a genetically edited pig heart in a pioneering between-species transplant that has been hailed as a success
The biotech industry is constantly searching for the perfect mutation, where properties from different proteins are synthetically combined to achieve a desired effect. It may be necessary to develop new medicaments or enzymes that prolong the shelf-life of yogurt, break down plastics in the wild, or make washing powder effective at low water temperature.
Davina McCall documentary highlights benefits and postcode lottery of previously rejected utrogestan A sought-after hormone replacement therapy is being reassessed for use in Scotland after the TV presenter and menopause campaigner Davina McCall revealed a postcode lottery in its prescription across the UK. Amid an ongoing supply crisis of HRT products , McCall spoke to specialists about the bene
Chinese capital ramps up efforts to control Omicron outbreak and avoid lockdowns See all our coronavirus coverage Beijing has reopened a mass isolation centre as authorities seek to contain an outbreak of Covid-19 in the city. The Xiaotangshan Fangcai hospital, which holds at least 1,200 beds and testing facilities, was first opened during the 2003 Sars epidemic, and used again in early 2020 to t
Scientists at Scripps Institution of Oceanography at UC San Diego, the J. Craig Venter Institute (JCVI), and the National Oceanic and Atmospheric Administration (NOAA) used tools of genetics research akin to those used in genealogical research to evaluate the diversity of marine life off the California coast.
A team of researchers at the Sloan Kettering Institute working with a group at the American Museum of Natural History has found evidence of a change in human DNA after diverging from other primates that has made humans more susceptible to the development of cancerous tumors. In their paper published in the journal Cell Reports, the group compares human genes to those of other primates to learn mor
Organisms such as plants, mammals and insects undergo a carefully orchestrated developmental program as they transition from single-celled embryos to their multicellular adult forms. In a paper that appeared May 4, 2022 in the journal Nature, researchers at Princeton University demonstrate how specialized genetic sequences coordinate the exquisite choreography of gene expression required for norma
Wealth inequality is a research topic typically reserved for humans. Now, research from the Max Planck Institute of Animal Behavior and the University of Nebraska-Lincoln suggests that studying wealth inequality in animals can help shed light on social evolution. Adapting approaches from the study of wealth inequality in humans, the researchers show how wealth—in the form of material goods, indivi
For much of American history, freedom from an oppressive legal system could be found by picking up and leaving. During the Great Migration, millions of Black Americans abandoned the Jim Crow South for the North, Midwest, and West; at a smaller scale, LGBTQ people have long fled communities where they felt unwelcome for liberal cities. On some level, Americans—with our unique system of federalism—
A team of scientists has created a three-dimensional map showing how a small molecule with anticancer properties—called spliceostatin—can promote the killing of cancer cells. This fundamental discovery could ultimately help researchers design future cancer drugs.
A new study by researchers at the National Institute of Standards and Technology (NIST) and collaborators highlights a sharp contrast between urban and suburban ways of thinking about coastal ecosystems.
Math has a certain logic to it. If you use it to accurately describe a situation, sometimes you can predict the inevitable — for instance, the moment an eclipse will take place — centuries in advance. To those unfamiliar with the math behind the prediction, this outcome might seem like magic. Indeed, the science fiction author Arthur C. Clarke famously wrote… Source
This is today's edition of The Download , our weekday newsletter that provides a daily dose of what's going on in the world of technology. Meta has built a massive new language AI—and it's giving it away for free Open to ideas: Meta's AI lab has created a massive new language model, and in an unprecedented move for Big Tech, it is giving it away to researchers—together with details about how it w
Researchers from Finland, Canada, and Russia have discovered an unusual, hourglass-shaped dust trail of the comet 17P/Holmes. The particles that formed the dust trail were released by the most powerful of the thus-far documented outbursts by a comet. It happened in October 2007. Astronomers carried out observations of the cometary dust trail using telescopes in Australia, Finland, and the U.S. The
LISA, the Laser Interferometer Space Antenna, has reached an important milestone: it has passed the comprehensive "Mission Formulation Review" (MFR) and now enters the next phase of development. The review team, consisting of experts from ESA, NASA, the scientific community and industry, identified no showstoppers and confirmed that LISA has successfully reached a maturity sufficient to proceed to
Since 2003, the black hole at the center of the Perseus galaxy cluster has been associated with sound. This is because astronomers discovered that pressure waves sent out by the black hole caused ripples in the cluster's hot gas that could be translated into a note—one that humans cannot hear, some 57 octaves below middle C. Now a new sonification brings more notes to this black hole sound machine
Ape Shit Imagine if all your favorite video games charged say, thousands of real dollars to customize your character. Every Sim's outfit, every Rocket League decal, every Among Us skin. Sure, plenty of games have microtransactions or in-app purchases, but you'd be hard pressed to find digital content that costs more than a few hundred dollars. Until now, that is, because in an absolutely incompre
The best parental control routers give parents the power to limit how long and what children can access online. The most robust parental controls let parents set use schedules, monitor activity, and use keywords to identify potentially harmful content. Your child's age, access to connected devices, and personality all factor into the type of parental controls you need in a router. If you have sev
A new study summarizing the 2020 California wildfire year said just over 9,900 wildfires burned 4.3 million acres in 2020. That's twice the previous record but only average compared to burn rates before Euro-American settlement. Fire severity is the far greater concern.
A study provides the first published in-depth description of the anti-cancer activity of capsaicin sustained release formulations. Capsaicin is naturally found in chili peppers and is the agent that provides the hot and spicy taste when eating chili peppers.
This is an edition of Up for Debate, a newsletter by Conor Friedersdorf. On Wednesdays, he rounds up timely conversations and solicits reader responses to one thought-provoking question. Every Monday, he publishes some thoughtful replies. Sign up for the newsletter here. Question of the Week What are your views on abortion? Email your thoughts to email@example.com . I'll publish a selection o
I'm currently in the process of learning how to process/analyze neuroimaging data. Is it standard practice (or at least accepted) to store these projects in GitHub ? Could I send my GitHub portfolio to labs I want to join along with my CV in order to demonstrate my skills? I am using publicly available data. If GitHub isn't a good option, how could I demonstrate my technical skills to labs apart
A new device uses millimeter-wave imaging — the same technology used in airport security scanners — to scan a patient's skin to detect if they have skin cancer. Millimeter-wave rays harmlessly penetrate about 2mm into human skin, so the team's imaging technology provides a clear 3D map of scanned skin lesions.
General relativity and quantum mechanics are the two most successful conceptual breakthroughs of modern physics, but Einstein's description of gravity as a curvature in space-time doesn't easily mesh with a universe made up of quantum wavefunctions. Recent work that tries to bring those theories together is revealing some mind-bending truths. In this episode, the physicist and author Sean Carroll
Scientists have developed a qubit platform formed by freezing neon gas into a solid, spraying electrons from a light bulb's filament onto it, and trapping a single electron there. This system shows great promise as an ideal building block for quantum computers.
Scientists from the Graduate School of Engineering Science at Osaka University have shown how silicon nanoparticles can become trapped inside the vortices that form inside superfluid helium. This work opens up new possibilities in optical research for other quantum properties of superfluid helium, such as the optical manipulation of quantized vortices due to the strong interaction between light an
Experts from the University of Nottingham have developed a common language to use on trigger and content warnings, after their research found that current warnings do not adequately take account of the needs of the intended audience.
New research led by Northwestern University can help officials identify hidden networks of officers engaging in misconduct and criminal behavior within police organizations. The study shows that police misconduct is a group phenomenon that contributes to a disproportionate number of arrests in minority communities.
Children whose parents cannot afford diapers do not get quality sleep, according to a new study. The study in the Journal of Developmental Behavioral Pediatrics is the first to examine the relationship between diaper need and sleep. "Sleep promotes brain development and solidifies learning and memory," says coauthor Sallie Porter, an associate professor at Rutgers University School of Nursing. "C
Abortion-rights supporters gathered and marched in cities across America following the leak of a draft majority opinion by U.S. Supreme Court Justice Samuel Alito, which suggests that the court intends to overturn the landmark Roe v. Wade ruling that gives Americans the right to have abortions. Though the document, published by Politico , has been confirmed as authentic in a statement by Chief Ju
Maehary bonapartei represents a small reptile that is considered to be the most basal of the evolutionary lineage that gave rise to pterosaurs. A study in PeerJ focuses on this latest find while also demonstrating that Faxinalipterus minimus is not a winged reptile, contrary to what was previously supposed.
With Australia's Covid cases per capita among the highest in the world, new antivirals such as Paxlovid and Lagevrio as well as intravenous treatments like sotrovimab are offering some hope for the severely ill, elderly and immunocompromised. However Australia's peak body for GPs says some people at greatest risk of dying from Covid are being prevented from accessing these treatments. Medical edi
Astronomers discovered a 'black widow binary' — a rapidly spinning neutron star circling and slowly consuming a smaller companion star. Named ZTF J1406+1222, the pair has the shortest orbital period yet identified, and is unique in that it appears to host a third star that orbits around the two inner stars every 10,000 years.
A protein called CDC7, long thought to play an essential role early in the cell division process, is in fact replaceable by another protein called CDK1, according to a study by investigators at Weill Cornell Medicine and the Dana Farber Cancer Institute. The finding represents a fundamental advance in cell biology and may lead to new cancer therapies, since cancers frequently alter the molecular m
There are three things that I remember from my high-school Earth-science class: the swirling pink cover of the study book designed to help us pass New York State's year-end test, the football player who seemed more intent on torturing me than on learning, and a nagging sense that what I was taking wasn't "really" science. The idea that Earth science barely counts as science is so woven into the e
Researchers demonstrated that the benefits of endurance exercise can vary based on the type of mutation involved in mitochondrial disease, and while the benefits of exercise tend to outweigh the risks, the mitochondrial genetic status of patients should be taken into consideration when recommending exercise as therapy.
Genes are the carriers of our genetic information. They are read in our cells and used to produce ribonucleic acids (RNAs). During this process, termed transcription, the enzyme RNA polymerase II has a decisive influence on the exact time at which genes are read and on the intensity with which this happens. In their recent article, researchers have shown exactly how RNA polymerase II is activated
After being pushed to the brink of extinction, California condors have returned to a slice of Northern California habitat for the first time in 130 years. On Tuesday, four of the big birds flew the coop after being born in a captive-breeding program.
Nature, Published online: 29 April 2022; doi:10.1038/d41586-022-01241-w They might be hard to love, but parasites are pivotal parts of the natural world. Plus, how language-generation AIs could transform science and the month's best science images.
After years of severe drought compounded by climate change, the water level in Lake Powell, the second-largest reservoir on the Colorado River, has dropped to just 24% of full capacity and is continuing to decline to levels not seen since the reservoir was filled in the 1960s.
More than 60 million magnetic resonance imaging (MRI) scans are performed worldwide each year, but imaging for the millions of patients with cardiac implantable electronic devices (CIEDs) such as pacemakers is a logistical challenge, because of concerns with how the magnetic field affects the implants. Now, a newly published study reveals safe and effective reprogramming of these devices is possib
Ecological flood control, i.e., measures that restore floodplains, is effective, technically possible and economically efficient. Yet, this approach is not consistently implemented worldwide because of the high administrative and legal hurdles. This is shown in a study by scientists from the Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB) who, together with other research instit
International scientists led by China's BGI-Research today published panoramic spatial atlases of life, examining the cellular dynamics of organisms at different developmental stages and providing potentially significant new information for disease treatment, development and aging as well as an improved understanding of biological evolution.
In the remote Andean community of El Cisne in Ingapirca, Ecuador, one of the first things you'll notice is children's laughter. In a courtyard, women gather with their children to trace ancestral knowledge and memories—and they do this using wool.
A team led by University of Minnesota Twin Cities researchers has revealed, for the first time, that landslides can have a major impact on the movement of glaciers. Using satellite imagery to study the effects of a 2019 landslide that occurred on the Amalia Glacier in the Patagonia region of Chile, the researchers found that the landslide caused the glacier to grow in size and has since slowed dow
French doctor and researcher Marthe Gautier, who died over the weekend, was one of a long line of women scientists who greatly contributed to scientific discovery only to see the credit go to their male colleagues.
A vast amount of the powerful greenhouse gas is sequestered as frozen crystals in the world's oceans. Of great concern among experts is the growing risk that, as the Earth warms and ocean temperatures rise, these highly disruptive, potent greenhouse gases will "flee" their frozen confinement.
Actions thought to be isolating and potentially detrimental for mental health, such as social distancing, can have a positive impact on well-being for many people when done together as part of a community, according to a global study led by Nottingham Trent University.
Market-ready fungi-based meat alternatives are similar to meat in taste and texture. They involve reduced land resources and greenhouse gas emissions from agriculture and land-use change. This goes under the assumption of a growing world population's increasing appetite for beefy bites, and it is the first time researchers have projected the development of these market-ready meat substitutes into
Researchers led by Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) have found that lifetime depression, trauma of having a loved one murdered, and post-traumatic stress disorder (PTSD) are the three greatest predictors of homelessness among U.S. Army soldiers after transitioning to civilian life. Their study, published in American Journal of Preventive Medicine, used an innov
The most recent United Nations climate change report indicates that without significant action to mitigate global warming, the extent and magnitude of climate impacts—from floods to droughts to the spread of disease—could outpace the world's ability to adapt to them. The latest effort to introduce meaningful climate legislation in the United States Congress, the Build Back Better bill, has stalled
Despite decades of study, black holes are still among the most powerful and mysterious celestial objects ever studied. Because of the extreme gravitational forces involved, nothing can escape the surface of a black hole (including light). As a result, the study of these objects has traditionally been confined to observing their influence on objects and spacetime in their vicinity. It was not until
In response to the shock of the COVID-19 pandemic, Congress pumped trillions of dollars into the economy in the form of stimulus checks, expanded unemployment benefits, and targeted spending to bolster specific industries such as airlines. The massive package apparently staved off a long, deep recession. But which elements were the most effective in the complicated, intertwined modern American eco
Research published in The European Physical Journal Plus shows that it is possible to classify rocks according to the size of the particles they contain during quarrying, using a portable Raman spectrometer.
Charles Darwin raised the question of whether darker skin is correlated with immunity to certain diseases in his 1871 book "The Descent of Man," an erroneous claim that reflected beliefs about the reality and fixity of race that were widespread in the mid-19th century, according to new Cornell research.
From Nike to Ben & Jerry's to Airbnb, more and more brands are taking a stand on sociopolitical issues (often called brand activism), to the point it's arguably become a component of any brand's strategy.
Animals have three main strategies to survive the freezing temperatures of winter: migrating, remaining in place and resisting the cold, and reducing body temperature and metabolic rate in a state called torpor.
Genes are the carriers of our genetic information. They are read in our cells and used to produce ribonucleic acids (RNAs). During this process, termed transcription, the enzyme RNA polymerase II has a decisive influence on the exact time at which genes are read and on the intensity with which this happens. In their recent Nature Communications article, researchers from the University of Bayreuth
Using second-long electrical shocks, scientists discovered they could control the types of cells in a community of bacteria. Being able to direct the ratio of cells holds implications for settings spanning agriculture to health care, where antibiotic resistance is a significant threat.
Plants can't speak up when they are thirsty. And visual signs, such as shriveling or browning leaves, don't start until most of their water is gone. To detect water loss earlier, researchers have created a wearable sensor for plant leaves. The system wirelessly transmits data to a smartphone app, allowing for remote management of drought stress in gardens and crops.
Using satellite imagery to study the effects of a 2019 landslide on the Amalia Glacier in Patagonia, a research team found the landslide helped stabilize the glacier and caused it to grow by about 1,000 meters over the last three years.
The Apple Watch may not have replicated the runaway success of the iPhone or iPad, but it's steadily grown into the best smartwatch available today. Apple has iterated on the hardware, designing custom processors that balance performance and battery life, while updating the software to add key features like the ability to run third-party apps, automatically track your exercise, and work more auto
Substituting 20 % of meat from cattle with microbial protein — a meat alternative produced in fermentation tanks — by 2050 could halve deforestation, a new analysis finds. The market-ready meat alternative is very similar in taste and texture, but is a biotech product which — by replacing beef — involves much less land resources and greenhouse gas emissions from agriculture and land-use change
Nature, Published online: 04 May 2022; doi:10.1038/d41586-022-01244-7 A forecast of the environmental benefits of switching to microbial protein, and the neurons that help mosquitoes home in on humans.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04531-5 The development of confined organocatalysts for the enantioselective cyanosilylation of small, unbiased substrates, including 2-butanone, is shown to lead to catalysts that are as selective as enzymes, with excellent levels of control.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04682-5 A survey of the CD4+ T cells in human melanomas indicates that immune evasion is mediated through direct stimulation of neoantigen-specific tumour-reactive regulatory T cells by HLA class II-positive melanoma cells.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04666-5 A method that uses a combination of optical trapping, fluorescence microscopy and microfluidics to analyse the internal structure of chromosomes shows that there is a distinct nonlinear stiffening of the chromosome in response to tension.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04685-2 A study using a mouse solid tumour model suggests that adjusting the dosing frequency of the PI3Kδ inhibitor AMG319 in the treatment of human cancers could decrease tumour growth with fewer adverse effects.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04539-x A solid-state single-electron qubit platform is demonstrated based on trapping and manipulating isolated single electrons on an ultraclean solid neon surface in vacuum, which performs near the state of the art for a charge qubit.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04680-7 In Drosophila, there are extensive physical and functional associations of distant paralogous genes, including co-regulation by shared enhancers and co-transcriptional initiation over distances of nearly 250 kilobases.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04629-w Replacing 20% of per-capita ruminant consumption with microbial protein can offset future increases in global pasture area, cut annual deforestation and related CO2 emissions in half, and lower methane emissions.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04695-0 The molecular determinants for primer synthesis are identified within the catalytic domain of primase-polymerase enzymes, elucidating the mechanisms underlying initiation of primer synthesis.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04513-7 Three tunable quantum Hall broken-symmetry states in charge-neutral graphene are identified by visualizing their lattice-scale order with scanning tunnelling microscopy and spectroscopy.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04551-1 ZTF J1406+1222 is a wide hierarchical triple system that hosts a low-metallicity subdwarf star and a 'black widow' millisecond pulsar that has a highly varying optical flux and a 62-minute period.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04520-8 Two new plasmon modes are observed in macroscopic twisted bilayer graphene with a highly ordered moiré superlattice, the first being the signature of chiral plasmons and the second a slow plasmonic mode around 0.4 electronvolts.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04667-4 Herpesvirus microRNAs interfere directly with host cell microRNA processing, thereby disrupting mitochondrial architecture, evading intrinsic host defences and driving the switch from latent to lytic infection.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04686-1 A study maps neuronal genomic targets of oestrogen receptor-α and shows how they coordinate brain sexual differentiation, concluding that the genome remains responsive to hormonal changes after structural dimorphisms have been established.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04523-5 The epitaxial growth of bilayer molybdenum disulfide on sapphire enables the fabrication of field-effect transistor devices with improved performance in carrier mobility and on-state current over traditional monolayer films.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04698-x In addition to CDC7, the cell cycle kinase CDK1 has a pivotal role in the G1/S transition of cells, a finding that revises our current understanding of cell cycle progression.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04514-6 A tuneable platform using twisted WTe2 stacks is described in which an electronic phase in the two-dimensional moiré lattice array is shown to resemble one-dimensional Luttinger liquids.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04561-z Micropillars made of liquid crystal elastomers and exposed to light exhibit diverse stroke-like motions, leading to complex dynamic pattern evolution and collective communication in arrays.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04684-3 A plant endogenous peptide-receptor signaling pathway termed SCREW–NUT is described; it counteracts microbe-associated molecular pattern (MAMP)- and abscisic acid-induced stomatal closure to regulate the reopening of stomata after biotic and abiotic stresses.
Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04675-4 Select chemical compounds enriched in human odour activate an olfactory glomerulus in the brain of Aedes aegypti mosquitoes, which strengthens host-seeking behaviour and helps explain their strong preference for biting humans.
Nature, Published online: 04 May 2022; doi:10.1038/d41586-022-01141-z Life on Earth depends on the ability of cells to duplicate their genetic material, encoded in DNA molecules, and pass this information on to the next generation. Elucidation of the molecular mechanism underlying the priming step of this copying process provides insights into how DNA replication begins.
Nature, Published online: 04 May 2022; doi:10.1038/d41586-022-01125-z Would environmental damage be reduced by replacing beef with mycoprotein produced in cell culture? Modelling shows that this change could greatly cut global deforestation, pasture area and greenhouse-gas emissions.
Nature, Published online: 04 May 2022; doi:10.1038/d41586-022-01080-9 The beating of hair-like structures that enable microorganisms to swim has been replicated in a polymer material that bends and twists with the help of light-sensitive molecular machines.
Nature, Published online: 04 May 2022; doi:10.1038/d41586-022-01128-w It has long been thought that two enzymes, the kinases CDC7 and CDK2, are both needed to trigger DNA replication in mammalian cells. This view is challenged by evidence that offers a revised view of which kinases are essential.
Nature, Published online: 04 May 2022; doi:10.1038/d41586-022-01192-2 The sixth and latest IPCC assessment weights climate models according to how well they reproduce other evidence. Now the rest of the community should do the same.
Vitamin B12 deficiency in infants leads to poor motor development and anemia, according to a study from Burkina Faso. B12 deficiency is an enormous yet overlooked problem and the current food relief is not helping. According to the researchers, the problem calls for new solutions. In Denmark, cases of poor psychomotor development are regularly seen in young children raised on vegan diets, though
Older adults are no more likely to believe fake news than younger adults, with age-related susceptibility to deceptive news evident only among those categorized as the "oldest old." Not being able to distinguish fake news from real news can have serious consequences for a person's physical, emotional, and financial well-being—especially for older adults, who in general have more financial assets
There's something wonderful about sitting under the night sky, watching a meteor shower play out overhead. However, observers in the southern hemisphere usually get the short end of the stick, with most of the best showers strongly favoring those north of the equator.
An independent researcher and one scientists from the University of Tennessee and one from Ancient Art Archive have revealed ancient Native American artwork inscribed on cave walls and ceilings in Alabama using 3D photogrammetry. In their paper published in the journal Antiquity, Alan Cressler, Jan Simek and Stephen Alvarez describe their work in documenting the ancient artwork.
Scientific Reports, Published online: 04 May 2022; doi:10.1038/s41598-022-11096-w Author Correction: De novo assembly, characterization, functional annotation and expression patterns of the black tiger shrimp ( Penaeus monodon ) transcriptome
Chemical engineering researchers have developed a faster, less expensive technique for producing hindered amines — a class of chemicals used as building blocks in products ranging from pharmaceuticals and agrochemicals to detergents and organic light emitting diodes.
A new study highlights a sharp contrast between urban and suburban ways of thinking about coastal ecosystems. The authors of the study used statistical and cognitive science techniques to analyze data from a survey of 1,400 residents across the U.S. East Coast. Their results showed that surveyed residents of urban centers often held a more simplistic, and less realistic, understanding of coastal e
New details of our past are coming to light, hiding in the nooks and crannies of the world, as we refine our techniques to go looking for them. Most lauded is the reconstruction of the evolution of humanity since our African origins around 300,000 years ago, by analyzing our living and fossil DNA. Replete with the ghosts of African and Eurasian populations of the deep past, these have been resurre
Microscopic imaging analysis is a crucial component of biochemistry and medicine, with significant progress in accuracy and speed made due to machine learning methods and improved computation. These technical advances can assist researchers adapt microscopy experimental plans online for real-time information of experimental observations. In a new study now published in Nature Communications, Zacha
Olena Koval found out that her husband was dead via text message. He was shot by Russian soldiers inside their home in Bucha while she was sheltering nearby, their neighbors told Human Rights Watch. In the days that followed, despite the brutal cold and her spinal disability, she made repeated attempts to recover his body but was turned back each time by the soldiers' threats.
The CMS collaboration at the Large Hadron Collider (LHC) has carried out a new test on a model that was developed to explain the tiny mass of neutrinos, electrically neutral particles that change type as they travel through space.
Scientists led by EPFL have developed a new method to measure chemical kinetics by imaging progress of a reaction at a liquid-liquid interface embedded in a laminar-flow liquid microjet. This method is ideal for studies of dynamics on the sub-millisecond timescale, which is very difficult to do with current applications.
A team led by City College of New York physicist Lia Krusin-Elbaum is behind research that could open a breadth of new quantum device platforms for harnessing emergent topological states for nano-spintronics and fault-tolerant quantum computing.
The name Emu Field does not have the same resonance as Maralinga in Australian history. It is usually a footnote to the much larger atomic test site in South Australia. However, the weapons testing that took place in October 1953 at Emu Field, part of SA's Woomera Prohibited Area, was at least as damaging as what came three years later at Maralinga.
Scientists have used tools of genetics research akin to those used in genealogical research to evaluate the diversity of marine life off the California coast. Large-scale 'metabarcoding' methods could revolutionize how society understands forces that drive seafood supply, planet's ability to remove greenhouse gases.
Squid, octopus, and cuttlefish — even to scientists who study them — are wonderfully weird creatures. Known as the soft-bodied or coleoid cephalopods, they have the largest nervous system of any invertebrate, complex behaviors such as instantaneous camouflage, arms studded with dexterous suckers, and other evolutionarily unique traits. Now, scientists have dug into the cephalopod genome to under
Seems like kids are always getting into something, so products marketed toward them often claim to repel liquids. Some items contain potentially harmful per- and polyfluoroalkyl substances (PFAS) to accomplish this feat, but companies aren't required to disclose these 'forever chemicals' on labels. Now, researchers show that some children's products advertised as water- or stain-resistant contain
The latest USC Polarization Index reveals that since President Joe Biden was elected, overall levels of polarization in the United States remain dangerously high, spurred on by increasing controversy around reproductive rights and LGBTQ+ issues.
Since graphene was first isolated and characterized in the early 2000s, researchers have been exploring ways to use this atomically thin nanomaterial because of its unique properties such as high tensile strength and conductivity.
When Eli Friedman set out to write his second book, he intended to focus on the segregated education system in China and how it affected teachers' work, but quickly found that the project moved in an unexpected direction.
A team of researchers at Charles Darwin University, in Australia, has found that male fish that mouth-brood are not always guaranteeing that the eggs they carry were fertilized by them. In their paper published in the journal Biology Letters, the group describes their study of the eggs brooded in the mouths of males of two species and what it taught them about monogamy in certain fish.
In the coming years and decades, critical minerals will start to rival oil and gas as the world's most sought-after commodities, and the US is currently not very well-positioned to compete in this new arena. China, on the other hand, has the minerals market pretty well cornered, from mining raw materials to refining and processing them. This week the Biden administration made a move to approach t
Stream Deadliest Catch on discovery+ ► https://www.discoveryplus.com/show/deadliest-catch #DeadliestCatch #Discovery #DiscoveryPlus Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Follow Us on TikTok: https://www.tiktok.com/@Discovery We're on Instagram! https://instagram.com/Discovery Join Us on Facebook: https://www.facebook.com/Discovery Follow Us on Twitter: https://twitter.com/Disco
Ny dansk forskning viser, at ikke kun mors type 1-diabetes kan have betydning for, hvor godt barnet klarer sig skolen. Det samme gælder, hvis far har type 1-diabetes. Alligevel er resultatet positivt, siger forsker.
Marijuana use and heart attack risk were correlated in a large human study, researchers report. A molecule in soybeans may counteract these effects. The study also shows that the psychoactive component of the drug, known as THC, causes inflammation in endothelial cells that line the interior of blood vessels, as well as atherosclerosis in laboratory mice. "As more states legalize marijuana use, I
Over the past two decades, more Black men have died from obstructive sleep apnea than have white people or Black women, a new study shows. Further, deaths of Black men from sleep apnea have continued to rise, in contrast to rates that have flattened for white people and Black women. The study in Sleep Medicine identifies for the first time this significant racial health disparity in mortality res
De sidste tre år har Sygeforsikringen "danmark" doneret penge til sundhedsdonationer. I år lyder beløbet på 150 mio. kr., som går til projekter inden for sundhedsfaglig forskning, forebyggelse og oplysning.
Nature, Published online: 04 May 2022; doi:10.1038/d41586-022-01148-6 Virologist Oyewale Tomori, whose career in science dates back to the early years of Nigerian independence, offers a personal perspective on the state of African science in 2022.
Ett stort engagemang. Men också ett stort tomrum när de nya eleverna försvann lika plötsligt som de kom. Så kan en del av landsbygdsskolors erfarenheter från flyktingvågen 2015 sammanfattas enligt en studie från Göteborgs universitet. Inlägget dök först upp på forskning.se .
Vad innebär det egentligen att vara människa i en tid som präglas av teknik som blir allt mer människolik – och som även tar allt större plats i vår vardag? Svaret söks i en ny avhandling från Umeå universitet. Inlägget dök först upp på forskning.se .
Unga män med högre inkomster och som överskattar sina finansiella kunskaper har lättare för att gå på finansiellt "skitsnack". Äldre kvinnor med lägre inkomst – som inte överskattar sina kunskaper i ekonomi – är inte lika mottagliga. Inlägget dök först upp på forskning.se .
Cannabisbruk kopplas till en ökad risk för annan droganvändning. Risken ökar också att drabbas av ångest och depression. Det visar en ny avhandling som även sett en rejäl ökning av cannabisrelaterade diagnoser inom sjukvården, särskilt hos yngre. Inlägget dök först upp på forskning.se .
Seems like kids are always getting into something, so products marketed toward them often claim to repel liquids. Some items contain potentially harmful per- and polyfluoroalkyl substances (PFAS) to accomplish this feat, but companies aren't required to disclose these "forever chemicals" on labels. Now, researchers reporting in ACS' Environmental Science & Technology show that some children's prod
For stor udskiftning i lægebemandingen fik sidste år Region Syddanmark til, ad to omgange, at opkræve en bod af det firma, som driver regionens udbudsklinik i Tønder. Og sådan vil det formentlig fortsætte indtil udgangen af 2023.
As in previous years, the spring break-up of river ice on the Tanana River at Nenana and the Yukon River at Dawson City in Canada (new! h/t Ed Wiebe), is a great opportunity to highlight phenology that indicates that the planet is in fact reacting to the ongoing global warming . This year, both rivers broke up on the same day (May 2nd) which is a little unusual. As we've done in previous years ,
After a series of delays, Rocket Lab has succeeded in catching one of its Electron rockets with a helicopter. While the operation was aborted before the booster could be landed safely, this is a big step toward a reusable launch system, something that has made Elon Musk's SpaceX a popular option for governments and industries. The Electron rocket is a much smaller vehicle than SpaceX's Falcon 9,
Nature, Published online: 04 May 2022; doi:10.1038/d41586-022-01202-3 Developers of artificial intelligence must learn to collaborate with social scientists and the people affected by its applications.
(Photo:Karsten Würth/Unsplash) A new solar-powered system out of Saudi Arabia is capable of producing two vital resources: energy and clean water. Peng Wang, an environmental scientist at the King Abdullah University of Science and Technology (KAUST), was working alongside a team of biologists and engineers to improve solar panels' efficiency when he thought of the idea for the system. Wang grew
Som noget nyt har Sygehus Sønderjylland valgt at slå hoveduddannelsesforløb i almen medicin på deltid op. Det skal give hospitalet i vandkantsdanmark en konkurrencefordel over for de større universitetshospitaler i jagten på yngre læger.
Those who feel certain about what the future of the COVID-19 pandemic would entail are more likely to both ignore medical experts and to adhere to conspiracy theories, finds a new study by a team of psychology researchers. Its results also show those who were certain about the outcome of the 2020 presidential election were more likely to contend that it was rigged.
Hovedstaden og Midtjylland melder sig som de første regioner til at udmønte deres andel af de årlige ti millioner kroner, som regeringen har sat til side til oprettelse af delestillinger. Nu skal Region Hovedstaden beslutte, hvilke områder der skal kunne søge om pengene.
Nature Communications, Published online: 04 May 2022; doi:10.1038/s41467-022-29986-y The construction of vicinal, congested stereocenters with high selectivities is of general utility in chemistry. Here the authors report a doubly-stereoconvergent, Cu/Mg-catalyzed asymmetric propargylic substitution reaction to convert simple starting materials to products with vicinal tertiary and all-carbon qua
Nature Communications, Published online: 04 May 2022; doi:10.1038/s41467-022-30176-z Aromatic tertiary amines are versatile building blocks in organic synthesis. In this article, the authors report on an iron-catalysed reaction for the decarboxylative C-N coupling from carboxylic acids and nitroarenes, leading to non-symmetric tertiary aromatic amines.
Nature Communications, Published online: 04 May 2022; doi:10.1038/s41467-022-30139-4 Coastal upwelling sustains some of the most productive ocean regions. Here, the authors find that spatial patterns and temporal changes in nutrient supply explain marine microbial community structure and diversity in the Southern California Current region.
Nature Communications, Published online: 04 May 2022; doi:10.1038/s41467-022-30122-z Randomness is perceived in two different extremes, in macroscopic homogeneity and local heterogeneity, but apparently far away from order. Here, the authors show that a periodic order can spontaneously arise from an ensemble of binary random copolymer sequences to induce recurrent folding of a self-assembled bila
Nature Communications, Published online: 04 May 2022; doi:10.1038/s41467-022-30146-5 In the summer, low-income households in the Arizona, US wait 4 – 7 °F (2.6–4.2 °C) longer than high-income households to turn on their AC units to save money on energy bills. This energy limiting behavior indicates a hidden form of energy poverty.
Nature Communications, Published online: 04 May 2022; doi:10.1038/s41467-022-30134-9 Here, Mac Kain and Maarifi et al. perform a functional CRISPR/Cas9 screen to identify SARS-CoV-2 restriction factors in A549 cells. They identify DAXX, a scaffold protein of nuclear bodies with diverse functions, that has anti-viral activity post SARS-CoV-2 entry, while SARS-CoV-2 has evolved a mechanism to count
Nature Communications, Published online: 04 May 2022; doi:10.1038/s41467-022-29990-2 Diodes are characterized by mono-directional flow of current, yet this simplicity belies their critical importance in electronics and optics. Here, Strambini et al demonstrate a superconducting quasi-particle equivalent, achieved by the use of a thin ferromagnetic insulator.
Scientific Reports, Published online: 04 May 2022; doi:10.1038/s41598-022-10473-9 Taphonomical analysis allows us to understand the processes that underlie site formation, as well as provide insights into the modification and composition of studied fossil materials. Taphonomy has become crucial to many scientific fields, providing conceptual advances through a renewal of models, protocols, and pa
Scientific Reports, Published online: 04 May 2022; doi:10.1038/s41598-022-11349-8 The development of Friedländer heteroannulation through a single electron transfer and energy transfer pathway using methylene blue (MB + )
(Photo: Iron Ox) A farm technology startup is using robots and artificial intelligence to tackle sustainability concerns in agriculture. Northern California-based Iron Ox was born from the realization that conventional American agriculture negatively impacts the environment in a multitude of ways. The type of farming most of us are familiar with uses as much as 70 percent of the world's fresh wat
As farmers face changing weather patterns, environmental degradation, labor shortages, and the rising cost of key supplies, no segment of agriculture is without passionate advocates of robotics and artificial intelligence as solutions. But the promises of precision agriculture still haven't been met.
There has hardly been a drop of rain in Hargududo in 18 months. Dried-up carcasses of goats, cows and donkeys litter the ground near the modest thatched huts in this small village in the Somali region of southeastern Ethiopia.
The number of people facing hunger rose to 193 million last year as conflict, climate change and economic crises ravaged people's livelihoods, the UN's Food and Agriculture Organization said Wednesday.
President Jair Bolsonaro's government has responded to less than three percent of deforestation alerts, a sign that "impunity reigns" in the destruction of Brazil's forests, an environmental monitor said Tuesday.
Researchers have developed and used a model to estimate the density of the golden-cheeked warbler, an endangered songbird that breeds in Ashe juniper and oak woodlands in central Texas. In a study published in the Journal of Wildlife Management, the team created a warbler distribution map that identifies areas important for conservation of the species, indicating places where improvement and resto
An article in Campbell Systematic Reviews reveals that there are surprisingly few high-quality studies that have examined the effects of reducing adult/child ratios and group sizes on factors such as young children's psychosocial adjustment, development, and well-being in early childhood education and care.
New research indicates that the veterinary profession responded well during the COVID-19 pandemic despite many dog owners feeling concerned about the availability of veterinary care during this time due to service restrictions.
The Earned Income Tax Credit (EITC)—a cash transfer program aimed at helping low to moderate income workers by giving them a break on their taxes—is not intended as a college subsidy, but the eligibility criteria for it incentivizes families sending children aged 19–23 years to college as this can increase EITC benefits by as much as $4,000 per year. An analysis in Economic Inquiry by researchers
A unique study conducting counts and surveys of unsheltered people in three parts of Los Angeles found that nearly half had been offered housing in the past, but they cited the housing intake process, desires for privacy and concerns about safety as obstacles they face in efforts to get off the streets, according to a new RAND Corporation report.
På hjerteafdelingerne er der frygt for, at rehabiliteringen efter hjertesygdom halter, efter at opgaven blev flyttet fra hospitalerne til primærsektoren. Men ingen ved det med sikkerhed, for der mangler data.
Frontotemporal demens startar relativt tidigt jämfört med andra demenssjukdomar och kunskapen om vad som orsakar sjukdomen är förhållandevis liten. Ny forskning från Lunds universitet visar att de veckningar i hjärnan som formas under senare delen av graviditeten kan ha betydelse för i vilken ålder som sjukdomen bryter ut.
The absence of signals from other advanced civilizations is, in fact, very bad news for humanity and modern civilization. On Earth, civilizations are short-lived. The Roman Empire lasted less than a thousand years, while the Maya civilization lasted about two thousand years. And the more developed a civilization, the less it exists. How much is ours? With such irresponsibility and the pace of con
Survivors of serious stroke can reduce their chances of dying within the year by 76% if they complete a modified cardiac rehabilitation program that includes medically supervised exercise, prescribed therapy, and physician follow-up, according to new research. The findings have the potential to change the future of stroke care.
When exploring a new environment, mice make use of a unique long-distance connection in the brain that prompts them to pay attention to the most salient features of the environment, according to new research. The link, originating in the prefrontal cortex and stretching to the hippocampus, provides evidence of how the brain's higher cognitive regions refine operations occurring in distant brain ar
A new study shows that young adults when sleep-deprived evaluate angry faces as less trustworthy and healthy-looking. Furthermore, neutral and fearful faces appear less attractive following sleep loss.
New research shows that children's willingness to study subjects like French, German or Spanish is shaped far more by the attitudes of their parents, than by their teachers or friends. The study's authors argue that efforts to reverse the steady decline in language-learning in the UK should target families rather than just children, because of the important role parents' beliefs play in shaping ch
An ecological protective coating, stronger yet less expensive than potentially dangerous beryllium shielding, is baked of alternating layers of sugar and silica. The simple result, which mimics the structure of a seashell, should lower costs for pulsed power machines and space satellites.
Storms in the Sahel region, which can reach over 100km in size, have become more extreme since the 1980s due to global warming, with more intense rainfall. An online portal will enable forecasters in West Africa to provide communities with earlier and more reliable warnings about large storms.
BioNyt Videnskabens Verden (www.bionyt.dk) er Danmarks ældste populærvidenskabelige tidsskrift for naturvidenskab. Det er det eneste blad af sin art i Danmark, som er helliget international forskning inden for livsvidenskaberne.
Bladet bringer aktuelle, spændende forskningsnyheder inden for biologi, medicin og andre naturvidenskabelige områder som f.eks. klimaændringer, nanoteknologi, partikelfysik, astronomi, seksualitet, biologiske våben, ecstasy, evolutionsbiologi, kloning, fedme, søvnforskning, muligheden for liv på mars, influenzaepidemier, livets opståen osv.
Artiklerne roses for at gøre vanskeligt stof forståeligt, uden at den videnskabelige holdbarhed tabes.