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Nyheder2022september15

Can we live longer? Physicist makes discovery about telomeres
With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery will help us understand aging and disease.
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Scientists hail autoimmune disease therapy breakthrough
Study finds CAR T-cell treatment sends lupus into remission, raising hopes it could be used to treat diseases such as multiple sclerosis Five people with severe autoimmune disease have become the first in the world to receive a groundbreaking therapy that uses genetically altered cells to drive the illness into remission. The four women and one man, aged 18 to 24, received transfusions of modifie
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Study shows potential of Southern cattail for phytoremediation of areas contaminated by mine tailings
Typha domingensis, the Southern cattail, a reedy marsh plant that inhabits fresh to slightly brackish waters and is about 2.5 m tall, can scavenge up to 34 times more manganese from contaminated soil than other plants found in similar environments. In a recent study, it accumulated between 10 and 13 times more manganese than other naturally occurring wetland plants such as hibiscus, sedges and rus
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Researchers attempt to print thin-film transistors with metal oxides onto heat-sensitive materials
Within the Functional Oxides Printed on Polymers and Paper (FOXIP) project, researchers form Empa, EPFL and the Paul Scherrer Institute attempted to print thin-film transistors with metal oxides onto heat-sensitive materials such as paper or PET. The goal was ultimately not achieved, but those involved consider the project a success—because of a new printing ink and a transistor with "memory effec
16min
molecular origin of the genetic disease cystinosis revealed
The rare genetic disease cystinosis is caused by mutations in the gene for a protein called cystinosin. A team of scientists has now solved the structure of cystinosin and determined how mutations interfere with its normal function, providing insights into the underlying mechanisms and suggesting a way to develop new treatments for the disease.
19min
The Woman King Is a War Film That's Actually Honest About War
The excitement of a historical war film is frequently at odds with the subject. War itself is miserable, complex, and sometimes lacking in heroic purpose. War movies , especially the Technicolor epics of old, tend to be thrilling affairs, in which stars triumph in the crucible of battle. Gina Prince-Bythewood's The Woman King, one of the director's largest-scale works to date, is packed with well
23min
Is neuroscience in a bad state?
I am considering getting into neuroscience, but apparently for one, cogsci researchers fail to (and have always failed to) reach consensus on anything, and for two, cogsci has always been, and is now more than ever, strongly dominated by psychologists, which seems detrimental to its goal of interdisciplinarity. There's an article going into more detail on this in the comments. I'd drop the link i
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Frank Drake (1930–2022)
Nature, Published online: 15 September 2022; doi:10.1038/d41586-022-02962-8 Radioastronomer who hunted for alien signals and penned the eponymous equation.
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Role of chemisorbing species in growth at liquid metal-electrolyte interfaces revealed by in situ X-ray scattering
Nature Communications, Published online: 15 September 2022; doi:10.1038/s41467-022-32932-7 Growth at liquid-liquid interfaces differ inherently from that on solids, making it attractive for nanomaterial formation. Here, the authors use X-ray scattering to derive a detailed microscopic picture of lead-halide growth on liquid mercury that reveals the key importance of anion adsorption.
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New Plan Suggests Re-Freezing Earth's Poles by Spraying Chemicals With Huge Military Jets
Climate Control A group of scientists propose unleashing huge amounts of microscopic aerosol chemicals from 125 massive military jets over the Earth's North and South Poles, in a desperate bid to refreeze the melting ice caps, Sky News reports — a plan that's already proving highly controversial among experts. To make a sizeable dent in the accelerating decline in ice shelves, we'd have to fly ro
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RiverProAnalysis, an open-source set of Matlab scripts for river longitudinal profile analysis
The erosional landscape evolves as the joint product of both tectonic activity and climate. The morphology of the long profiles of active rivers has been proven to be an archive to preserve and record the relationship of topographic relief, temporary and/or differential rock uplift rate, and climatically and/or lithologically related erosional efficiency. A simple but universal equation of the str
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PDGFR kinase inhibitor found to protect against septic death via regulation of BTLA
In a study was led by Dr. Jianxin Jiang (Institute of Department of Trauma Medical Center, Daping Hospital, State Key Laboratory of Trauma, Burns and Combined Injury, Army Medical University), a team screened a highly selective kinase inhibitor library and found that CP-673451 can upregulate BTLA expression on immunocytes and reduce sepsis-related mortality.
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YouTuber Clambers Inside Chernobyl's Nuclear Sarcophagus
Duke Nukem In October 2021, months before Russia's invasion of Ukraine, YouTuber Kyle Hill got a rare glimpse inside the New Safe Confinement (NSC) "sarcophagus" at the Chernobyl nuclear plant. It's a fascinating glimpse behind the scenes, a rare tour of the ground zero of one of the worst nuclear disaster in human history — and a terrifying reminder of what is at stake given the ongoing war in t
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An AI that can design new proteins could help unlock new cures and materials
A new AI tool could help researchers discover previously unknown proteins and design entirely new ones. When harnessed, it could help unlock the development of more efficient vaccines, speed up research for the cure to cancer, or lead to completely new materials. Alphabet-owned AI lab DeepMind took the world by surprise in 2020 when it announced AlphaFold, an AI tool that used deep learning to so
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Donkey genome reveals journey to domestication
Scientists have sequenced the genome of the donkey, revealing the journey it took toward domestication. Sometimes overlooked, donkeys have their own unique and significant history, which tells how they evolved right alongside humans. The new research clarifies the key role they played in daily human life dating back thousands of years. Researchers sequenced the genome of donkeys from regions arou
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'Moderately weak' ties best for moving jobs, study finds
Research using LinkedIn finds most useful acquaintances share a handful of mutual contacts Whether it's the friend of a friend or a new contact from a conference, arms-length acquaintances have long been thought more useful than close chums when it comes to switching jobs. Now researchers say they have finally found a way to test the theory, revealing that while such "weak ties" do seem to facili
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Saturn's rings the remnants of a moon that strayed too close, say scientists
Theory of inner satellite ripped apart by gas giant's gravity 100m-200m years ago also explains rings' relative youth Saturn's famous rings could be the aftermath of a moon that was ripped apart by the planet's gravity, according to scientists. The research, based on data from the final stage of Nasa's Cassini mission, suggests that Saturn may have been ringless for almost all of its 4.5bn-year e
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Greener and more 'walkable' urban areas encourage physical activity
Urban areas with more "walkable" and greener environments favor the practice of physical activity among citizens. This is the result of a study conducted by researchers from the Institute of Environmental Science and Technology (ICTA-UAB) of the Universitat Autònoma de Barcelona that provides public decision-makers with valuable indications on how to design healthy urban environments in the future
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Researchers pave the way for large-scale, efficient organic solar cells with water treatment
Organic solar cells (OSCs), which use organic polymers to convert sunlight into electricity, have received considerable attention for their desirable properties as next-generation energy sources. These properties include its lightweight nature, flexibility, scalability, and a high power conversion efficiency (>19%). Currently, several strategies exist for enhancing the performance and stability of
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NASA's Perseverance rover investigates geologically rich Mars terrain
NASA's Perseverance rover is well into its second science campaign, collecting rock-core samples from features within an area long considered by scientists to be a top prospect for finding signs of ancient microbial life on Mars. The rover has collected four samples from an ancient river delta in the Red Planet's Jezero Crater since July 7, bringing the total count of scientifically compelling roc
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In memoriam | Science
The Science family mourns longtime copyeditor Jeffrey Cook, who died unexpectedly last month. Jeff joined AAAS in 1994. He was a true perfectionist and cared deeply about language, editing, and scientific communication. Thousands of Science papers published over the past three decades are clearer and more accurate because of Jeff's meticulous dedication to his craft. He deftly transitioned from th
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Ecological footprint of Russia's Ukraine invasion | Science
Russia's invasion of Ukraine continues to have a devastating effect on the well-being of Ukrainians and their economy (1). The tragic human consequences will be compounded by the long-term ecological implications of the war, such as the contamination of soil and water by the weaponry and other pollutants, wildfires and disruptions to ecosystem structure and services, and the environmental impact o
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Comprehensive support for diversity in STEM | Science
In their Policy Forum "Achieving STEM diversity: Fix the classrooms" (3 June, p. 1057), J. Handelsman et al. explain that past interventions have not resulted in equitable representation for students from historically excluded communities in science, technology, engineering, and mathematics (STEM). We agree that implementation of their suggested classroom changes would likely contribute to greater
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A genomics revolution in amphibian taxonomy | Science
FULL ACCESSLetter Share on A genomics revolution in amphibian taxonomyChristophe Dufresnes [email protected] and Daniel JablonskiScience15 Sep 2022Vol 377, Issue 6612p. 1272DOI: 10.1126/science.ade5002 PREVIOUS ARTICLEDos and don'ts for achieving managerial diversityPreviousNEXT ARTICLEComprehensive support for diversity in STEMNext References and NotesAmphibians feature the highest rates of bo…
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High seas treaty within reach | Science
The ocean is Earth's greatest climate mitigator, but it cannot do its work without biodiversity. Yet, accelerating climate change, unsustainable fishing, and widespread plastic and other pollutants, combined with increased resource demands, are …
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Talk with your hands? You might think with them too!
Scientists observed how the brain responds to words representing hand-manipulable objects, when a participant's hands were either free to move or restrained. They showed that brain activity in response to hand-manipulable words was significantly reduced by hand restraints. Verbal responses were also affected by hand constraints. Their results support the idea of embodied cognition, which proposes
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Scientists resolve the structure of the human bitter taste receptor TAS2R46
A team of scientists led by the iHuman Institute of ShanghaiTech University has determined and analyzed the cryo-electron microscopy structures of human bitter taste receptor TAS2R46 complexed with G protein, in both strychnine-bound and apo forms, providing the first three-dimensional image of a human taste receptor. This study was published as the research article in the latest issue of Science.
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Humidity-sensitive chemoelectric flexible sensors based on metal-air redox reaction for health management
Nature Communications, Published online: 15 September 2022; doi:10.1038/s41467-022-33133-y Self-powered sensors are of interest in wearable technology and other applications. Here, the authors report on the creation of a metal-air redox reaction humidity sensor where the conductance and charge generated is influenced by the amount of absorbed water and demonstrate application in respiration monit
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Millions of farmers 'replumb' the world's largest delta
Collective groundwater pumping by millions of farmers in Bangladesh in the dry season each year has created vast natural reservoirs underground that, over a 30-year-period, rival the world's largest dams—these sustain irrigation that has transformed this previously famine-prone country to a food-secure nation, according to a new study led by UCL researchers.
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Scientists resolve the structure of the human bitter taste receptor TAS2R46
A team of scientists led by the iHuman Institute of ShanghaiTech University has determined and analyzed the cryo-electron microscopy structures of human bitter taste receptor TAS2R46 complexed with G protein, in both strychnine-bound and apo forms, providing the first three-dimensional image of a human taste receptor. This study was published as the research article in the latest issue of Science.
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Saturn's rings and tilt could be the product of an ancient, missing moon
Swirling around the planet's equator, the rings of Saturn are a dead giveaway that the planet is spinning at a tilt. The belted giant rotates at a 26.7-degree angle relative to the plane in which it orbits the sun. Astronomers have long suspected that this tilt comes from gravitational interactions with its neighbor Neptune, as Saturn's tilt precesses, like a spinning top, at nearly the same rate
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Scientists find 'weaker ties' are more beneficial for job seekers on LinkedIn
Employment is a critical issue impacting the economy, and it gained even more attention during the pandemic with the elimination or transformation of tens of millions of jobs around the world. As much of the economy becomes digitized, it is important to consider the effect of social media and social networks on jobs. A team of researchers from Harvard, Stanford, MIT and LinkedIn, led by recent Sta
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The Best Books for a Broken Heart
For years after my last failed relationship, I would hoard lines from books that seemed to describe my ex perfectly and devastatingly. "It gratified him to feel like a desperate man," Willa Cather writes of the surly husband, Frank, in O Pioneers! "His unhappy temperament was like a cage; he could never get out of it; and he felt that other people, his wife in particular, must have put him there.
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Interfacial-induced fabrication of porous carbon with enhanced intrinsic active sites
Carbon catalysis is an attractive metal-free catalytic transformation, and its performance is significantly dependent on the number of accessible active sites. However, owing to the inherent stability of the C–C linkage, only limited active sites at the edge defects of the basal plane can be obtained even after a harsh oxidation treatment. Therefore, to promote the development of carbocatalysis, i
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Researchers discover new signal for triggering human immune response
Researchers from Cleveland Clinic's Florida Research and Innovation Center (FRIC) found that disruption of a cellular structure, known as the actin cytoskeleton, is a "priming signal" for the body to respond to a virus. These findings, published in Cell this week, potentially lay the groundwork for development of new anti-viral vaccines and treatments.
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Nanoplastics can disrupt human liver and lung cell processes in lab experiments
What happens when people unknowingly eat, drink or inhale nearly invisible pieces of plastic? Although it's unclear what impact this really has on humans, researchers have now taken a step toward answering that question. In Environmental Science & Technology, a team reports laboratory results indicating that tiny plastic particles could enter liver and lung cells and disrupt their regular processe
2h
Physicists generate new nanoscale spin waves
Strong alternating magnetic fields can be used to generate a new type of spin wave that was previously just theoretically predicted. This was achieved for the first time by a team of physicists from Martin Luther University Halle-Wittenberg (MLU). They report on their work in Nature Communications and provide the first microscopic images of these spin waves.
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Study shows flerovium is the most volatile metal in the periodic table
An international research team gained new insights into the chemical properties of the superheavy element flerovium—element 114—at the accelerator facilities of the GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt. The measurements show that flerovium is the most volatile metal in the periodic table. Flerovium is thus the heaviest element in the periodic table that has been chemically st
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Researchers discover new signal for triggering human immune response
Researchers from Cleveland Clinic's Florida Research and Innovation Center (FRIC) found that disruption of a cellular structure, known as the actin cytoskeleton, is a "priming signal" for the body to respond to a virus. These findings, published in Cell this week, potentially lay the groundwork for development of new anti-viral vaccines and treatments.
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Furious Crypto Miners Making Their Own Ethereum Where They Can Still Destroy the Environment After the Merge
EthereumPoW The Etherum Merge hath befallen! Basically, what's arguably the world's most influential crypto project decided to ditch the environmentally harmful proof-of-work model for a greener proof-of-stake system. It's a much-anticipated experiment — but one group isn't too thrilled about the change . According to Fortune , a group of cryptocurrency miners — many of whom stand to lose their m
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The Entire Food Chain Has Started Collapsing, Scientists Warn
Tangled Web According to 130,000 years' worth of data on what mammals have been eating, we're in the midst of a mass biodiversity crisis . Not great! This revelation was borne of a new study, conducted by an international team of researchers and published in the journal Science , that used machine learning to paint a detailed past — and harrowing future — of what happens to food webs when land ma
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Path to the brown coloration of diatoms discovered
Diatoms are microscopic unicellular algae occurring in natural waters worldwide. During photosynthesis, they take up large quantities of carbon dioxide, the primary greenhouse gas emitted through human activities, and convert it into biomass. The carotenoid fucoxanthin enables diatoms to efficiently harvest the blue-green part of the sunlight for photosynthesis. An international research team now
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Swimmer's itch: What causes this neglected snail-borne disease?
Cercarial dermatitis is caused by the larvae of blood flukes that are parasites of birds or mammals. A new study suggests that a cercarial dermatitis outbreak in South Thailand was caused by the blood fluke Schistosoma indicum. The study offers important insights on these parasites, which, apart from being a public health issue, can also infect livestock animals, threatening the sustenance of peop
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Nanoplastics can disrupt human liver and lung cell processes in lab experiments
What happens when people unknowingly eat, drink or inhale nearly invisible pieces of plastic? Although it's unclear what impact this really has on humans, researchers have now taken a step toward answering that question. In Environmental Science & Technology, a team reports laboratory results indicating that tiny plastic particles could enter liver and lung cells and disrupt their regular processe
2h
Discovery of extinct prehistoric reptile that lived among dinosaurs
Researchers have discovered a new extinct species of lizard-like reptile that belongs to the same ancient lineage as New Zealand's living tuatara. A team of scientists describe the new species Opisthiamimus gregori, which once inhabited Jurassic North America about 150 million years ago alongside dinosaurs like Stegosaurus and Allosaurus. In life, this prehistoric reptile would have been about 16
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New X-Ray Technique Could Help Detect Explosives, Tumors
The inside of a bag viewed with UCL's X-ray system. (Photo: Patridge et al/Nature Communications) A new X-ray technique that combines conventional equipment with a deep-learning algorithm might find its way into both security settings and the healthcare industry. Researchers from the United Kingdom's University College London (UCL) recognized that X-ray security systems, though good at detecting
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Reactor uses 'supercritical' water to destroy forever chemicals
A new reactor completely breaks down hard-to-destroy forever chemicals using "supercritical water," which is formed at high temperature and pressure, researchers report. Forever chemicals, named for their ability to persist in water and soil, are a class of molecules that are ever-present in our daily lives, including food packaging and household cleaning products. Because these chemicals don't b
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How to keep kids curious: Five questions answered
Kids are naturally curious. But various forces in the environment can dampen their curiosity over time. Can anything be done to keep kids' curiosity alive? For answers to this question, The Conversation U.S. turned to Perry Zurn, a philosophy professor at American University and author of three books on curiosity, including "Curious Minds: The Power of Connection," which was released in September
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It takes a laboratory to avoid data loss
Nature, Published online: 15 September 2022; doi:10.1038/d41586-022-02967-3 Lab members are typically in charge of their own data and notes. But institutional memory is better served if the team works together, say Stephen McInturff and Victor Adenis.
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Solvent effect on film formation and device performance for 2D Dion-Jacobson perovskite solar cells
Quasi two-dimensional perovskite solar cells (2D PSCs) have received much attention recently due to their unique optoelectronic properties and excellent device stability. Among 2D perovskite, 2D Dion-Jacobson (DJ) perovskite has closer interlayer distance and does not rely on van der Waals interaction between adjacent spacer cations, which can weaken dielectric confinement effect while maintaining
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Disadvantaged population groups perceive their capabilities to promote individual health and well-being as weak
Young people not in education, employment or training, long-term unemployed, people with refugee backgrounds, and older people living alone and at risk of exclusion perceive their capabilities to promote their individual health and well-being as weak. A new study shows that these people also perceived their quality of life to be weaker than the Finnish population on average.
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Study reveals the molecular origin of the genetic disease cystinosis
The rare genetic disease cystinosis is caused by mutations in the gene for a protein called cystinosin. A team of scientists has now solved the structure of cystinosin and determined how mutations interfere with its normal function, providing insights into the underlying mechanisms and suggesting a way to develop new treatments for the disease.
3h
T cells use force to destroy cancer cells
As a part of our immune defenses, cytotoxic T cells—or killer T cells—seek out and destroy cells that are infected or cancerous. This process is essential for the body's defense against diseases.
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Nanoplastics can disrupt human liver, lung cells' processes in lab experiments
What happens when people unknowingly eat, drink or inhale nearly invisible pieces of plastic? Although it's unclear what impact this really has on humans, researchers have now taken a step toward answering that question. A team now reports laboratory results indicating that tiny plastic particles could enter liver and lung cells and disrupt their regular processes, potentially causing adverse heal
3h
Engineering an enzyme against antibiotic-resistant anthrax
In the 2001 'Amerithrax' attacks, anthrax-causing spores were sent through the mail to media outlets and members of Congress, sickening at least 22 people and killing five. Antibiotic-resistant strains of the bacteria are of growing concern, and researchers are preparing to fight back. Now, a team has taken a step toward the development of a therapeutic that can treat the infection in mice without
3h
What will we learn from the period of mourning for the Queen?
Experts say this week can provide new insights into group behaviour and how it influences identity and society Death of the Queen and King Charles's accession – latest updates In the strange, wild days after the death of Diana, Princess of Wales, when heaps of flowers rotted in their plastic outside town halls across the country and the Daily Mail vowed never again to print a paparazzi photo, Gal
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Can CBD treat postmenopausal women?
Cannabidiol, a major component of hemp and medical marijuana, may be an effective treatment for postmenopausal women, whose ovaries no longer make estrogen, a new study with mice shows. Cannabidiol (CBD) is already used to treat conditions such as chronic pain , inflammation, migraines, epilepsy, autoimmune diseases, depression, and anxiety. In the study in Frontiers in Pharmacology , the researc
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Urologist Powers Vasectomy With Electric Pickup Truck During Blackout
As if all-electric trucks weren't hardcore enough . Austin-based urologist Christopher Yang ran a long extension cord from his Rivian R1 T pickup truck to one of his patient's rooms to literally power a vasectomy procedure during a prolonged Texas power outage, Illinois State University's public radio station WGLT reported earlier this month . It's perhaps the pinnacle of what electric pickup tru
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Yes, GE's $28 LED+ Smart Light Bulb Is Also a Bluetooth Speaker
When you think of iconic duos throughout history, a few immediately come to mind: Mario and Luigi, Bonnie and Clyde, Batman and Robin, and Bluetooth speakers and smart light bulbs. If that last pairing seems out of place, you probably haven't heard about GE's LED+ Speaker . Let's cut to the chase. This is a $28 smart lightbulb with a Bluetooth speaker inside, and while the combination might seem
4h
Engineering an enzyme against antibiotic-resistant anthrax
In the 2001 'Amerithrax' attacks, anthrax-causing spores were sent through the mail to media outlets and members of Congress, sickening at least 22 people and killing five. Antibiotic-resistant strains of the bacteria are of growing concern, and researchers are preparing to fight back. Now, a team has taken a step toward the development of a therapeutic that can treat the infection in mice without
4h
Three ways companies change their products to hide inflation
Consumer price inflation in the U.K. slowed for the first time in nearly a year in August. A fall in petrol prices helped slow the overall rate but food prices continue to rise rapidly. But even with a slowdown to 9.9%, from 10.1% in July, inflation still remains close to the highest its been for a generation.
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Why it's not anti-environmental to be in favor of economic growth
In the midst of today's cost of living crisis, many people who are critical of the idea of economic growth see an opportunity. In their recent book The Future is Degrowth, for example, prominent advocates Matthias Schmelzer, Aaron Vansintjan and Andrea Vetter argue that the post-COVID inflation has predominantly been caused by the inherent instability in the capitalist system.
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The medicine of ants: Rescue and treatment of injured individuals
The African Matabele ant (Megaponera analis) lives dangerously when hunting able-bodied termites. However, the animals do not simply give up their wounded. Depending on the degree of injury, they rescue and treat them. Injured individuals decide for themselves whether they will be helped. If a specimen demands rescue, it remains calm, releases pheromones, and allows itself to be carried back to th
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Why the body positivity movement risks turning toxic
You define beauty yourself. You are more than a number on a scale. Love yourself the way you are. Body positive messages like these seem to be everywhere from social media to TV ads. But while some find the body positivity movement to be uplifting and helpful, others have begun calling the movement "toxic" and suggesting it may be time to move on from this way of thinking.
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The direct observation of highly nonlinear plasma waves
Over the past few decades, physicists and engineers have been trying to create increasingly compact laser-plasma accelerators, a technology to study matter and particle interactions produced by interactions between ultrafast laser beams and plasma. These systems are a promising alternative to existing large-scale machines based on radio-frequency signals, as they can be far more efficient in accel
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An AI used medical notes to teach itself to spot disease on chest x-rays
After crunching through thousands of chest x-rays and the clinical reports that accompany them, an AI has learned to spot diseases in those scans as accurately as a human radiologist. The majority of current diagnostic AI models are trained on scans labeled by humans, but that labeling is a time-consuming process. The new model, called CheXzero, can instead "learn" on its own from existing medica
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Customer experience and the future of work
Major trends such as the impact of covid-19 on accelerating digital commerce, remote and hybrid working, and changing employee expectations driving the "great resignation" are having profound effects on workforce strategies in contact centers worldwide. Indeed, as an industry that requires a high volume of employees, often in hourly paid positions, and with roles becoming increasingly enabled by
4h
The medicine of ants: Rescue and treatment of injured individuals
The African Matabele ant (Megaponera analis) lives dangerously when hunting able-bodied termites. However, the animals do not simply give up their wounded. Depending on the degree of injury, they rescue and treat them. Injured individuals decide for themselves whether they will be helped. If a specimen demands rescue, it remains calm, releases pheromones, and allows itself to be carried back to th
4h
The Bioteque: A computational tool to harmonize biological knowledge
The rapid development of the different disciplines in the fields of biological and biomedical research (such as genomics, proteomics, and transcriptomics) in recent decades has led to exponential growth in the amount of biological data available. For example, at the European Bioinformatics Institute (EMBL-EBI), they have gone from managing a volume of 40 petabytes to working with 250 petabytes in
4h
Researchers discover extinct prehistoric reptile that lived among dinosaurs
Smithsonian researchers have discovered a new extinct species of lizard-like reptile that belongs to the same ancient lineage as New Zealand's living tuatara. A team of scientists, including the National Museum of Natural History's curator of Dinosauria Matthew Carrano and research associate David DeMar Jr. as well as University College London and Natural History Museum, London scientific associat
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What They Aren't Telling You About Hypoallergenic Dogs
As someone with dog allergies who nevertheless has been around many dogs as a trainer, a fosterer, and an owner, Candice has learned not to trust the promise of a "hypoallergenic" dog. She's met low-shedding, hypoallergenic poodles and Portuguese water dogs that supposedly shouldn't trigger her allergies yet very much did. But she has also met fluffy, longhaired breeds such as huskies and spitzes
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Cross Your Fingers: NASA Reschedules Artemis 1 Launch, Again
Image: NASA/Joel Kowsky Artemis draws back her bow afresh. After scrubbing two launch attempts in rapid succession, NASA has set a new launch window for its Space Launch System's Artemis 1 mission to the moon. Including the scrubbed launch attempts from the past two weeks, NASA still has never done a successful test of the SLS rocket's cryofuel systems. But it's hoping to change that record, star
5h
The Bioteque: A computational tool to harmonize biological knowledge
The rapid development of the different disciplines in the fields of biological and biomedical research (such as genomics, proteomics, and transcriptomics) in recent decades has led to exponential growth in the amount of biological data available. For example, at the European Bioinformatics Institute (EMBL-EBI), they have gone from managing a volume of 40 petabytes to working with 250 petabytes in
5h
How songbirds' striking colors put them at risk
Bright, uniquely colored songbirds are at higher risk of extinction and more likely to be traded as pets, according to researchers reporting in Current Biology on September 15. The researchers also predict that almost 500 additional bird species, most of them living in the tropics, are at risk of future trade based on their unique and desirable coloration.
5h
Researchers discover extinct prehistoric reptile that lived among dinosaurs
Smithsonian researchers have discovered a new extinct species of lizard-like reptile that belongs to the same ancient lineage as New Zealand's living tuatara. A team of scientists, including the National Museum of Natural History's curator of Dinosauria Matthew Carrano and research associate David DeMar Jr. as well as University College London and Natural History Museum, London scientific associat
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Study: Astronomers risk misinterpreting planetary signals in James Webb data
NASA's James Webb Space Telescope is revealing the universe with spectacular, unprecedented clarity. The observatory's ultrasharp infrared vision has cut through the cosmic dust to illuminate some of the earliest structures in the universe, along with previously obscured stellar nurseries and spinning galaxies lying hundreds of millions of light years away.
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Exploring is good for teens, but comes with risks
Teenagers become more given to exploration with age and become increasingly likely to visit new places over time, a study finds. The results also show that greater exploration is associated with enhanced psychological well-being and larger social networks. The researchers also discovered that adolescents who explored their natural environments more also reported a greater number of risky behavior
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Surgery has cut death rate from torn aorta
The chance of a patient living after tearing their aorta has improved significantly, but the condition remains deadly if not recognized early and repaired surgically, a study finds. A team of researchers examined early mortality rates for over 5,600 patients admitted to the hospital and examined hourly with type A acute aortic dissection between 1996 and 2018 from the International Registry for A
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Understanding how a cell becomes a person, with math
We all start from a single cell, the fertilized egg. From this cell, through a process involving cell division, cell differentiation and cell death a human being takes shape, ultimately made up of over 37 trillion cells across hundreds or thousands of different cell types.
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Conversion to LED lighting brings new kind of light pollution to Europe
A team of researchers at the University of Exeter has found that the slow conversion of outdoor lighting to LEDs across much of Europe has led to the development of a new kind of light pollution. In their paper published in the journal Science Advances, the group describes their study of photographs taken from the International Space Station.
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A library of polytypic copper-based quaternary sulfide nanocrystals enables efficient solar-to-hydrogen conversion
Nature Communications, Published online: 15 September 2022; doi:10.1038/s41467-022-33065-7 While polytypic semiconductors are promising for solar-to-fuel applications, preparing homojunction nanomaterials has proven challenging. Here, authors obtain a library of polytypic copper-based quaternary sulfide nanocrystals by selective epitaxial growth of kesterite phase on wurtzite structure.
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Chaos Researchers Can Now Predict Perilous Points of No Return
Predicting complex systems like the weather is famously difficult. But at least the weather's governing equations don't change from one day to the next. In contrast, certain complex systems can undergo "tipping point" transitions, suddenly changing their behavior dramatically and perhaps irreversibly, with little warning and potentially catastrophic consequences. On long enough timescales… Sour
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Observing the difference in structural dynamics of 1 nm single-molecules at room temperature for the first time
Chemists' long-held dream of observing the structural dynamics of a single molecule have been now been made possible. Single molecules sized about 1 nanometer exist in a volatile state under ambient conditions. Considering that the coronavirus, which is about 100 nm in size, spreads rapidly in the air shows how difficult it is to observe a single molecule. Recently, a Korean research team has disc
5h
Using governance to spur, not stall, data access for analytics
Data governance has historically been a serious bottleneck for analytics. While managing data to ensure it complies with policies and regulations is important, these processes can also make it difficult to locate and access data. Businesses that govern data at scale, in real time, and in the cloud often find the situation even more complicated. After all, what good are real-time data streams if g
5h
Observing the difference in structural dynamics of 1 nm single-molecules at room temperature for the first time
Chemists' long-held dream of observing the structural dynamics of a single molecule have been now been made possible. Single molecules sized about 1 nanometer exist in a volatile state under ambient conditions. Considering that the coronavirus, which is about 100 nm in size, spreads rapidly in the air shows how difficult it is to observe a single molecule. Recently, a Korean research team has disc
6h
Novel glucagon-like peptide-1 drugs designed for type 2 diabetes
Novel glucagon-like peptide-1 (GLP-1) drugs were designed and industrially prepared by researchers at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences through molecular design, strain construction, isolation and purification, and animal experiments, according to a paper published in Pharmaceuticals.
6h
Humans Destroyed Forests for Thousands of Years. We Can Become the First Generation to Expand Them
For thousands of years humans have destroyed forests. At the end of the last great ice age, an estimated 57 percent of the world's habitable land was forested. 1 Since then, people in all regions of the world have burned and cut down forests. The chart below shows this. The forested land area declined from six to four billion hectares. That means our ancestors destroyed one-third of the former fo
6h
Daily briefing: The most climate-friendly seafood
Nature, Published online: 14 September 2022; doi:10.1038/d41586-022-02956-6 Farmed shellfish is nutritious and low-carbon — but wild-caught crustaceans have a carbon footprint right up there with beef. Plus, what scientists are learning about severe monkeypox and a five-year campaign breaks science's citation paywall.
6h
Landscape and climate factors can predict prevalence of Lyme disease bacteria
Predicting Lyme disease hotspots can help public health officials guide resources and proactive messaging to the public. But the ecology of the disease is complex, involving various host animals, black-legged ticks that serve as a disease vector, the disease-causing agent itself, the bacteria Borrelia burgdorferi, and the environment in which they all live.
6h
Put a ring on it: How gravity gives astronomers a powerful lens on the universe
In 1919 astronomers Arthur Eddington and Andrew Crommelin captured photographic images of a total solar eclipse. The sun was in the constellation Taurus at the time, and a handful of its stars could be seen in the photographs. But the stars weren't quite in their expected place. The tremendous gravity of the sun had deflected the light of these stars, making them appear slightly out of place. It w
6h
Byzantine solar eclipse records illuminate obscure history of Earth's rotation
Witnessing a total solar eclipse is an unforgettable experience and may have been even more impressive throughout history before we were able to understand and accurately predict their occurrence. But the historical records of these remarkable astronomical spectacles are more than mere curiosities—they provide invaluable information on changes in the Earth's movement.
6h
Can we live longer? Physicist makes discovery about telomeres
With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery will help us understand aging and disease.
6h
Landscape and climate factors can predict prevalence of Lyme disease bacteria
Predicting Lyme disease hotspots can help public health officials guide resources and proactive messaging to the public. But the ecology of the disease is complex, involving various host animals, black-legged ticks that serve as a disease vector, the disease-causing agent itself, the bacteria Borrelia burgdorferi, and the environment in which they all live.
6h
I'm an expert in crowd behaviour – don't be fooled that everyone queueing in London is mourning the Queen | Stephen Reicher
Despite what we hear from the media, the reasons so many are gathering are complex and various Britain is in mourning. This is affirmed every time we turn on the television and see the huge numbers of people watching royal processions, or willing to queue for long hours to file past the Queen's casket. They have gathered, we are told, "to pay their respects". They are there "to thank the Queen".
6h
Popular sport fish are behaviorally impaired from exposure to crude oil, study finds
A first-of-its-kind research experiment led by researchers at University of Miami (UM) Rosenstiel School of Marine, Atmospheric, and Earth Science confirmed that a popular sport fish exposed to sublethal levels of crude oil and released back into the wild exhibits altered behavior, decreased survival, and reduced spawning.
6h
Researchers prepare nacre-inspired underwater superoleophobic films
Special wettability of solid surfaces is a ubiquitous phenomenon in nature and has attracted much attention because of its potential applications in diverse fields, such as oil-water separation, antibiofouling and drag reduction. Inspired by some biological organisms observed in nature with underwater superoleophobic properties, such as fish scales, columnar nacre and seaweed, researchers are tryi
6h
Of God and Machines
This article was featured in One Story to Read Today, a newsletter in which our editors recommend a single must-read from The Atlantic , Monday through Friday. Sign up for it here. M iracles can be perplexing at first , and artificial intelligence is a very new miracle. "We're creating God," the former Google Chief Business Officer Mo Gawdat recently told an interviewer. "We're summoning the demo
6h
Feedbacks between sea-floor spreading, trade winds and precipitation in the Southern Red Sea
Nature Communications, Published online: 15 September 2022; doi:10.1038/s41467-022-32293-1 Testing feedbacks between climatic and geological processes are challenging. Here, the authors show that geomorphological features of the southern Red Sea margin are best interpreted by a feedback cycle between orographic precipitation, mid-ocean spreading and coastal magmatism, and that the feedback is enh
6h
Phototunable chip-scale topological photonics: 160 Gbps waveguide and demultiplexer for THz 6G communication
Nature Communications, Published online: 15 September 2022; doi:10.1038/s41467-022-32909-6 6G communication requires high-speed and advanced functionalities on-chip. Here the authors demonstrate broadband phototunable topological waveguide and demultiplexing chip with record single-channel 160 Gbit/s communication link and excellent channel isolation for 300 GHz band.
6h
The complement C3-complement factor D-C3a receptor signalling axis regulates cardiac remodelling in right ventricular failure
Nature Communications, Published online: 15 September 2022; doi:10.1038/s41467-022-33152-9 Right ventricular (RV) failure is clinically crucial, but there is no specific therapy. Here, the authors show that the complement alternative pathway is activated in RV failure and that blockade of the pathway ameliorates RV failure in mice.
6h
Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis
Nature Communications, Published online: 15 September 2022; doi:10.1038/s41467-022-33171-6 Besides hepatocytes, resident immune cells of the liver are also contributing to the body's energy homeostasis. Here authors show that group 2 innate lymphoid cells interact with a specific set of hepatocytes in suppressing gluconeogenesis and regulate blood glucose levels via Interleukin-13 signalling.
6h
Path to the brown coloration of diatoms discovered
Diatoms are microscopic unicellular algae occurring in natural waters worldwide. During photosynthesis, they take up large quantities of carbon dioxide, the primary greenhouse gas emitted through human activities, and convert it into biomass. The carotenoid fucoxanthin enables diatoms to efficiently harvest the blue-green part of the sunlight for photosynthesis.
6h
Path to the brown coloration of diatoms discovered
Diatoms are microscopic unicellular algae occurring in natural waters worldwide. During photosynthesis, they take up large quantities of carbon dioxide, the primary greenhouse gas emitted through human activities, and convert it into biomass. The carotenoid fucoxanthin enables diatoms to efficiently harvest the blue-green part of the sunlight for photosynthesis.
7h
Researchers prepare nacre-inspired underwater superoleophobic films
Special wettability of solid surfaces is a ubiquitous phenomenon in nature and has attracted much attention because of its potential applications in diverse fields, such as oil-water separation, antibiofouling and drag reduction. Inspired by some biological organisms observed in nature with underwater superoleophobic properties, such as fish scales, columnar nacre and seaweed, researchers are tryi
7h
Small proteins play big role in cellular energy balance
Scientists at Duke-NUS Medical School have discovered new molecular details of how cells ensure that their energy supply is adjusted to meet energy demand. Their study, carried out in collaboration with researchers at the University of Melbourne in Australia and Duke University in Durham, North Carolina, U.S., highlights the crucial role microproteins play in assembling larger protein complexes in
7h
New, comprehensive framework could better inform carbon-cutting policies
As countries around the world look to reduce carbon emissions, China, currently the largest emitter of carbon dioxide with 30% of global total carbon emissions in 2018, has declared its goal of being carbon neutral by 2060. To achieve this goal, China—and any other countries with similar climate-change mitigation goals—will need to implement the most effective mix of transportation-sector policies
7h
Bevis för att det funnits sjöar i Saharaöknen
Analys av fossila alger ger bevis för att det funnits sjöar i Sahara under Afrikas "gröna period" för 5 000 till 10 000 år sedan. Att förstå hur klimatet i öknen har förändrats historiskt kan ge en fingervisning om Saharas framtid. Inlägget dök först upp på forskning.se .
7h
Uggla kan ge räddning för hörselskadad
Hörselbenet hos hornugglan kan tjäna som förebild till framtida hörselproteser, eftersom det är stabilt och har god förmåga att vidarebefordra ljud. Det visar en avhandling från Umeå universitet. Inlägget dök först upp på forskning.se .
7h
Small proteins play big role in cellular energy balance
Scientists at Duke-NUS Medical School have discovered new molecular details of how cells ensure that their energy supply is adjusted to meet energy demand. Their study, carried out in collaboration with researchers at the University of Melbourne in Australia and Duke University in Durham, North Carolina, U.S., highlights the crucial role microproteins play in assembling larger protein complexes in
7h
Quitline area code matters for outreach to smokers
Using a local area code can make a quitline more successful with English- and Spanish-speaking smokers. New findings published in Nicotine & Tobacco Research show the simple but valuable approach can help engage low-income smokers to try quitting tobacco. The study tested a proactive, phone-based outreach strategy using local vs. generic caller area codes. Researchers called English and Spanish-s
7h
The Download: The Merge arrives, and China's AI image censorship
This is today's edition of The Download , our weekday newsletter that provides a daily dose of what's going on in the world of technology. The Merge is here: Ethereum has switched to proof of stake What's happened: "The Merge", a major upgrade to the Ethereum cryptocurrency platform, was finally completed early this morning after a six-year buildup. Ethereum now uses proof of stake, a way to appr
7h
NASA's CAPSTONE Moon Probe Is Tumbling After Unknown Error
NASA is still working toward getting Artemis 1 off the ground , which is arguably the most important milestone in its quest to return humankind to the lunar surface. However, things are not going well with the first mission of the Artemis Program. The CAPSTONE probe, which launched in June aboard a Rocket Lab Electron rocket , is tumbling and partially disabled. It's currently in safe mode, but i
8h
Nvidia RTX 4090 Pictured, Final Specs for 40-Series Leaked
(Photo: @wxnod on Twitter ) The launch of Nvidia's RTX 40-series is now less than a week away, and the floodgates have opened. New photos have leaked of the flagship RTX 4090 GPU, along with specs for the 4090 and 4080s. Yes, we wrote 4080 plural, as there appear to be two SKUs. We don't have official pricing or availability, but there's still a lot to pore over. The first RTX 4090 GPUs to say he
8h
AI Art Is Here
Recently an artist names Jason Allen won the Colorado State Art Fair's competition in the category of digital art with a picture (shown) that was created by an AI, the Midjourney software. This has triggered another round of angst over computers taking our jobs. Some have declared it the end of art, or that it will destroy the jobs of working artists. This development can certainly be a job-kille
8h
Go ahead, ask for help. It makes people happy
People regularly underestimate others' willingness to help, new research suggests. We shy away from asking for help because we don't want to bother other people, assuming that our request will feel like an inconvenience to them. But oftentimes, the opposite is true: People want to make a difference in people's lives and they feel good —happy even—when they are able to help others, says Stanford U
8h
Grain boundary structural transformation induced by co-segregation of aliovalent dopants
Nature Communications, Published online: 15 September 2022; doi:10.1038/s41467-022-32935-4 The effect of aliovalent doping on grain boundary is not yet fully understood at the atomic level. Here, the authors report grain boundary structural transformation in α-Al2O3 is induced by co-segregation of multiple dopants using atomic-resolution electron microscopy and theoretical calculations.
8h
Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity
Nature Communications, Published online: 15 September 2022; doi:10.1038/s41467-022-32701-6 Lineage plasticity is increasingly recognized as an emergent resistance mechanism after treatment with androgen receptor signalling inhibitors. To understand determinants of resistance, the authors analyzed the transcriptomes of patient tumor biopsies before enzalutamide treatment and at progression and ide
8h
Spontaneous spin-valley polarization in NbSe2 at a van der Waals interface
Nature Communications, Published online: 15 September 2022; doi:10.1038/s41467-022-32810-2 Van der Waals heterostructures made of 2D materials offer a rich platform for the study of novel proximity effects. Here, by means of Hall effect measurements, the authors show a proximity-induced ferromagnetic/ferrovalley ground state with spontaneous spin-valley polarization in a V5Se8/NbSe2 heterostructu
8h
In situ X-ray and acoustic observations of deep seismic faulting upon phase transitions in olivine
Nature Communications, Published online: 15 September 2022; doi:10.1038/s41467-022-32923-8 This paper shows that formation of thin weak layers filled with nanocrystalline olivine/wadsleyite, upon the pressure-induced phase transition of olivine, is the major cause of deep-focus earthquakes on the metastable olivine wedge in deep slabs.
8h
11 Ancient Solutions for Modern Malaise
" How to Build a Life " is a weekly column by Arthur Brooks, tackling questions of meaning and happiness. Click here to listen to his podcast series on all things happiness, How to Build a Happy Life . "All men, brother Gallio, wish to live happily," wrote the Roman philosopher and statesman Lucius Annaeus Seneca to his brother around A.D. 58, "but are dull at perceiving exactly what it is that m
9h
King Charles Should Get Ready to Abdicate
When Britain's longest-serving monarch, Queen Elizabeth II, died last week, a 73-year-old man ascended to the throne. King Charles III, né Prince Charles, is expected to continue his longtime focus on climate change among his many duties as the United Kingdom's head of state. If he lives as long as his mother did, he could spend more than two decades as monarch. But a more consequential use of Ch
9h
Why This Election Is So Weird
T he two major factors shaping the 2022 midterm elections collided in tumultuous fashion on Tuesday morning. First came the government report that inflation last month had increased faster than economists had expected or President Joe Biden had hoped. The announcement triggered a sharp fall in the stock market, the worst day on Wall Street in two years. That same afternoon, Senator Lindsey Graham
9h
Fireball spotted crossing the night sky over Glasgow – video
Footage circulating on social media purports to show a fireball crossing the sky over Glasgow. Astronomers say the fireball crossed over Scotland and Northern Ireland on Wednesday evening. The UK's Meteor Network say they have received more than 800 reports of sightings and now believe it was 'space debris' 'Incredible' fireball crosses sky over Scotland and Northern Ireland Continue reading…
10h
How journal editors kept questionable data about women's health out of the literature years before retractions
In July of 2017, Mohamed Rezk, of the department of obstetrics and gynecology at Menoufia University in Egypt, submitted a manuscript to the journal Anesthesia with a colleague. The manuscript, "Analgesic and antiemetic effect of Intraperitoneal magnesium sulfate in laparoscopic salpingectomy: a randomized controlled trial," caught the attention of John Carlisle, an editor at the … Continue readin
10h
Global warming doubled the risk for Copenhagen's historic 2011 cloudburst
Researchers at the University of Copenhagen, in collaboration with the Danish Meteorological Institute (DMI), have used detailed weather models to clearly tie increased temperatures to the historic cloudburst over Copenhagen in July of 2011. New methods involving counterfactual weather forecasts could link the weather event to global warming for the first time.
10h
Fireball over Scotland and NI no longer thought to be Elon Musk 'space junk'
UK Meteor Network says it 'cannot find any known space junk or satellite de-orbit' to explain object A fireball seen over Scotland and Northern Ireland is no longer believed to have been space junk from Elon Musk's satellite programme, according to astronomers examining it. The UK Meteor Network said the fireball was visible for 20 seconds just after 10pm on Wednesday night. It received almost 80
11h
EEG-Experiment download
Hello, I just got my EEG-Hardware and I try to find some experiments online where I can test the whole setup. Is there a place where I can download specific experiments for an EEG? I tried to find some on pavlovia (python), but they dont really have a big selection. submitted by /u/semaxX [link] [comments]
11h
New atlas of bird migration shows extraordinary journeys
A bay-breasted warbler weighs about the same as four pennies, but twice a year makes an extraordinary journey. The tiny songbird flies nearly 4,000 miles (6,437 kilometers) between Canada's spruce forests and its wintering grounds in northern South America.
11h
A new space race? China adds urgency to US return to moon
It's not just rocket fuel propelling America's first moonshot after a half-century lull. Strategic rivalry with China's ambitious space program is helping drive NASA's effort to get back into space in a bigger way, as both nations push to put people back on the moon and establish the first lunar bases.
12h
US moved online, worked more from home as pandemic raged
During the first two years of the pandemic, the number of people working from home in the United States tripled, home values grew and the percentage of people who spent more than a third of their income on rent went up, according to survey results released Thursday by the U.S. Census Bureau.
12h
The Merge is here: Ethereum has switched to proof of stake
"The Merge", a major upgrade to the Ethereum cryptocurrency platform, was finally completed today after a six-year buildup . As of 2:43 ET this morning, Ethereum now uses proof of stake, a way to approve new transactions that promises to cut the blockchain's energy requirements by 99.9% and usher in a new era for the second-largest cryptocurrency. It would be hard to overstate how much industry e
12h
Opinion: Feminist Science Is Not an Oxymoron
Mainstream scientists have often believed feminist ideals are incompatible with true science — that the former is about ideology; the latter, objective authority. Yet feminists have generated a set of tools to make science less biased and more robust. More scientists could benefit from it.
12h
Murine fetal bone marrow does not support functional hematopoietic stem and progenitor cells until birth
Nature Communications, Published online: 15 September 2022; doi:10.1038/s41467-022-33092-4 Relatively little is known about the first hematopoietic stem and progenitor cells to arrive in the fetal bone marrow. Here they characterize the frequency, function, and molecular identity of fetal BM HSPCs and their bone marrow niche, and show that most BM HSPCs have little hematopoietic function until bi
12h
Skeptical Science New Research for Week #37 2022
Mutual assured stupefaction A plethora of investigations have found that come the clutch, ideology often wins over facts when it comes to uncomfortable truths. If the outcomes of facts disagree with ideological objectives, facts frequently lose. Why? If we look at the sharpest divergences of facts from wishful ideology, we find a common element: truth as best we know it, information showing the n
13h
Children whose parents breathed cigarette smoke more likely to get asthma – study
Research offers evidence that tobacco could damage health of people two generations later Children are much more likely to develop asthma if their father was exposed to tobacco smoke when he was growing up, a new study has found. And they are at even greater risk of suffering from the common lung condition if their father was a smoker himself, according to the international team of researchers. C
14h
Scientists try to teach robot to laugh at the right time
Research team hopes system could improve natural conversations between humans and AI systems Laughter comes in many forms, from a polite chuckle to a contagious howl of mirth. Scientists are now developing an AI system that aims to recreate these nuances of humour by laughing in the right way at the right time. The team behind the laughing robot, which is called Erica, say that the system could i
15h
How air pollution is changing our view of cancer – podcast
According to the World Health Organisation, air pollution causes 7 million premature deaths every year . We've known for a long time that air pollution causes lots of health problems, including lung cancer – but exactly how the two were linked was somewhat of mystery. Last week, a team from the Francis Crick Institute and University College London presented findings that shed new light on the rol
15h
How air pollution is changing our view of cancer
According to the World Health Organisation, air pollution causes 7 million premature deaths every year. We've known for a long time that air pollution causes lots of health problems, including lung cancer – but exactly how the two were linked was somewhat of mystery. Last week, a team from the Francis Crick Institute and University College London presented findings that shed new light on the role
15h
Americans' civics knowledge has dipped again
Less than half of Americans could name the three branches of United States government in a recent survey. The University of Pennsylvania's Annenberg Public Policy Center's annual, nationally representative survey showed notable increases in 2020 and 2021 after tumultuous years that put the role of government and the three branches under a media spotlight. In those two years, the survey took place
16h
Tiny, caterpillar-like soft robot folds, rolls, grabs and degrades
When you hear the term 'robot,' you might think of complicated machinery working in factories or roving on other planets. But 'millirobots' might change that. They're robots about as wide as a finger that someday could deliver drugs or perform minimally invasive surgery. Now, researchers have developed a soft, biodegradable, magnetic millirobot inspired by the walking and grabbing capabilities of
18h
One of Long COVID's Most Misunderstood Symptoms
This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. Sign up for it here . Brain fog is one of the most destructive symptoms of long COVID—and one of the most misunderstood. In a recent story , our staff writer Ed Yong explains why the condition should not be conflated with
20h
Backbone's One Controller Unlocks the iPhone's True Gaming Potential
Let me be blunt: The Backbone One gaming controller is the iPhone accessory I've wanted since games started appearing on Apple's smartphone platform in 2008. It fulfills the promise of turning the iPhone into a credible Nintendo Switch competitor, and distinguishes itself in a field crowded with alternatives from companies like Razer, GameSir, and even Microsoft, Sony, and Nintendo. Read on for o
21h
Using artificial intelligence to improve tuberculosis treatments
Researchers used data from large studies that contained laboratory measurements of two-drug combinations of 12 anti-tuberculosis drugs. Using mathematical models, the team discovered a set of rules that drug pairs need to satisfy to be potentially good treatments as part of three- and four-drug cocktails.
21h
Seven healthy lifestyle habits may reduce dementia risk for people with diabetes
A combination of seven healthy lifestyle habits including sleeping seven to nine hours daily, exercising regularly and having frequent social contact was associated with a lower risk of dementia in people with type 2 diabetes, according to a study published in the September 14, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.
22h
Who Knows What Putin Will Do Next?
This is an edition of Up for Debate, a newsletter by Conor Friedersdorf. On Wednesdays, he rounds up timely conversations and solicits reader responses to one thought-provoking question. Later, he publishes some thoughtful replies. Sign up for the newsletter here. Question of the Week What will determine your vote––or your decision to refrain from voting––in the 2022 midterm elections? What issue
22h
Removing turf-grass saves water. But will it increase urban heat?
As Las Vegas and other Southwestern cities look for ways to reduce water use during a historic drought, the removal of grass lawns and other areas of "nonfunctional turf" has been recommended by the Southern Nevada Water Authority and written into Nevada state law with AB356. But, will this change from turf-grass to other landscaping types result in other unintended climate impacts in urban areas,
22h
Astronomers Are Losing Their Minds Over "Breathtaking" New James Webb Images
Hyped Up The James Webb Space Telescope continues to wow even the most no-nonsense scientists, as evidenced by a statement put out by some of the NASA craft's Canadian collaborators. "We are blown away by the breathtaking images of the Orion Nebula," Els Peeters, an astrophysicist at Ontario's Western University, said in a statement about a newly-released set of images that show more of the famed
22h
Scientists Have a Hack for Having More Sex in Long-Term Relationships
Anyone who's been in a long-term relationship knows that sex and desire can wane over time, even as you feel more emotionally intimate with the other person. According to a new study, though, there's a relatively easy way to bring the spark back. As spotted by Psychology Today , a recent paper in the Journal of Social and Personal Relationships examines the concepts of closeness, otherness, and s
22h
Using artificial intelligence to improve tuberculosis treatments
Imagine you have 20 new compounds that have shown some effectiveness in treating a disease like tuberculosis (TB), which affects 10 million people worldwide and kills 1.5 million each year. For effective treatment, patients will need to take a combination of three or four drugs for months or even years because the TB bacteria behave differently in different environments in cells—and in some cases
22h
Using artificial intelligence to improve tuberculosis treatments
Imagine you have 20 new compounds that have shown some effectiveness in treating a disease like tuberculosis (TB), which affects 10 million people worldwide and kills 1.5 million each year. For effective treatment, patients will need to take a combination of three or four drugs for months or even years because the TB bacteria behave differently in different environments in cells—and in some cases
22h
Scientist discovers new oxidation state of rhodium
Chemists have discovered a new oxidation state of rhodium. This chemical element is one of the most catalytically important platinum-group metals and is used, for example, in catalytic converters for automobiles. Rhodium is actually already well studied.
23h
global states of consciousness as formulated in the Upanishads
I am interested in our sense of self , particularly the cognitive mechanisms that underlie it. I write a substack column trying to illustrate the issues in layman terms. As I am sure most peeps on this subreddit are very aware, consciousness studies always seem to crash into the "hard problem" of consciousness, popularized by David Chalmers and 'defined' by Thomas Nagel in his famous essay here.
23h
Food Delivery Robot Plows Through Crime Scene as Cops Look on in Bemusement
Robot Trespasser A Los Angeles food delivery robot threw caution to the wind and forced itself across a police line. A video shared on Twitter shows the four-wheeled delivery bot passing between several photographers before ploughing through yellow police tape into a scene crowded with cops. LAPD officers mostly ignored the trespasser, allowing it to pass through unimpeded. In sidelong glances, t
23h
The bolder bird gets (and keeps) the girl
Researchers demonstrate a clear connection between personality in wandering albatross (Diomedea exulans) and the likelihood of divorce. Though the link between personality and relationship outcomes in humans is well-established, this is the first study to do so with animals.
23h
Soybean virus may give plant-munching bugs a boost in survival
Most viral infections negatively affect an organism's health, but one plant virus in particular — soybean vein necrosis orthotospovirus, often referred to as SVNV — may actually benefit a type of insect that commonly feeds on soybean plants and can transmit the virus to the plant, causing disease, according to new research.
23h
The John Durham Probe Gave Trump What He Wanted
John Durham, the U.S. attorney whom former Attorney General Bill Barr appointed to investigate the origins of the investigation into Russian interference in the 2016 election, is reportedly near to wrapping up his work . The grand jury he was using to hear evidence is expiring; there's no indication he will convene another, and members of his team are leaving, having produced a rather thin record
23h
Many older adults use meds to block arthritis pain
Taking a pill may bring short-term relief for arthritis-related joint pain, but many older adults may not realize that what they swallow could raise their risk of other health problems, according to a new poll. Even if they're managing the pain on their own, people over 50 should talk to their health care providers about what they're taking, and get advice about potential medication risks and non
23h
Computational Modeling of DNA Communication in the Nucleus
http://www.iBiology.org What do chromosomes look like in our cells? In this 2022 Share Your Research Talk, Wang describes his research to build a mathematical model for a process called Loop Extrusion, which describes how DNA folds and forms loops at kilobase scale. This model helps us understand complex interactions between DNA fragments as well as their 3D structure. The model can be used to pr
23h
Wang Xi interview, Share Your Research series
http://www.iBiology.org As part of the 2022 Share Your Research Talk series, we interviewed this year's speakers. Wang Xi, PhD tells us what fascinates him about science, what he enjoys about doing research, and what motivated him to study DNA. Speaker Biography: Wang Xi, PhD completed his doctoral program at Johns Hopkins University. At the time of filming, Wang was a PhD candidate and his thesi
23h
The emergence of spontaneous coordinated epithelial rotation on cylindrical curved surfaces | Science Advances
Abstract Three-dimensional collective epithelial rotation around a given axis represents a coordinated cellular movement driving tissue morphogenesis and transformation. Questions regarding these behaviors and their relationship with substrate curvatures are intimately linked to spontaneous active matter processes and to vital morphogenetic and embryonic processes. Here, using interdisciplinary a
1d
In situ diagnosis and simultaneous treatment of cardiac diseases using a single-device platform | Science Advances
Abstract The in situ diagnosis of cardiac activities with simultaneous therapeutic electrical stimulation of the heart is key to preventing cardiac arrhythmia. Here, we present an unconventional single-device platform that enables in situ monitoring even in a wet condition and control of beating heart motions without interferences to the recording signal. This platform consists of the active-matr
1d
Lost in translation: Molecular basis of reduced flower coloration in a self-pollinated monkeyflower (Mimulus) species | Science Advances
Abstract Phenotypic evolution is usually attributed to changes in protein function or gene transcription. In principle, mutations that affect protein abundance through enhancing or attenuating protein translation also could be an important source for phenotypic evolution. However, these types of mutations remain largely unexplored in the studies of phenotypic variation in nature. Through fine-sca
1d
Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation | Science Advances
Abstract The mechanistic target of rapamycin complex 1 (mTORC1) regulates cell growth and catabolism in response to nutrients through phosphorylation of key substrates. The tumor suppressor folliculin (FLCN) is a RagC/D guanosine triphosphatase (GTPase)–activating protein (GAP) that regulates mTORC1 phosphorylation of MiT-TFE transcription factors, controlling lysosome biogenesis and autophagy. W
1d
Asymmetric multifunctionalization of alkynes via photo-irradiated organocatalysis | Science Advances
Abstract Alkynes represent a family of pivotal and sustainable feedstocks for various industries such as pharmaceuticals, agrochemicals, and materials, and they are widely used as important starting materials for the production of a broad range of chemical entities. Nevertheless, efficient structural elaborations of alkynes in chemical synthesis, especially asymmetric multifunctionalization of al
1d
A self-generated Toddler gradient guides mesodermal cell migration | Science Advances
Abstract The sculpting of germ layers during gastrulation relies on the coordinated migration of progenitor cells, yet the cues controlling these long-range directed movements remain largely unknown. While directional migration often relies on a chemokine gradient generated from a localized source, we find that zebrafish ventrolateral mesoderm is guided by a self-generated gradient of the initial
1d
Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response | Science Advances
Abstract The receptor binding domain (RBD) of the SARS-CoV-2 spike protein is the primary target of neutralizing antibodies and is a component of almost all current vaccines. Here, RBD immunogens were created with stabilizing amino acid changes that improve the neutralizing antibody response, as well as characteristics for production, storage, and distribution. A computational design and in vitro
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Nanofloating gate modulated synaptic organic light-emitting transistors for reconfigurable displays | Science Advances
Abstract The use of postsynaptic current to drive long-lasting luminescence holds a disruptive potential for harnessing the next-generation of smart displays. Multiresponsive long afterglow emission can be achieved by integrating light-emitting polymers in electric spiked transistors trigged by distinct presynaptic signals inputs. Here, we report a highly effective electric spiked long afterglow
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Observation of robust zero-energy state and enhanced superconducting gap in a trilayer heterostructure of MnTe/Bi2Te3/Fe(Te, Se) | Science Advances
Abstract The interface between magnetic material and superconductors has long been predicted to host unconventional superconductivity, such as spin-triplet pairing and topological nontrivial pairing state, particularly when spin-orbital coupling (SOC) is incorporated. To identify these unconventional pairing states, fabricating homogenous heterostructures that contain such various properties are
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Inhibition of Chk2 promotes neuroprotection, axon regeneration, and functional recovery after CNS injury | Science Advances
Abstract DNA double-strand breaks occur in many acute and long-term neurological conditions, including neurodegeneration, neurotrauma, and stroke. Nonrepaired breaks chronically activate the DNA damage response in neurons, leading to neural dysfunction and apoptosis. Here, we show that targeting of the central ATM-Chk2 pathway regulating the response to double-strand breaks slows neural decline i
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Making a case for femto-phono-magnetism with FePt | Science Advances
Abstract In the field of femtomagnetism, magnetic matter is controlled by ultrafast laser pulses; here, we show that coupling phonon excitations of the nuclei to spin and charge leads to femto-phono-magnetism, a powerful route to control magnetic order at ultrafast times. With state-of-the-art theoretical simulations of coupled spin, charge, and lattice dynamics, we identify strong nonadiabatic s
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Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases | Science Advances
Abstract CRISPR-Cas9 gene editing has emerged as a powerful therapeutic technology, but the lack of safe and efficient in vivo delivery systems, especially for tissue-specific vectors, limits its broad clinical applications. Delivery of Cas9 ribonucleoprotein (RNP) owns competitive advantages over other options; however, the large size of RNPs exceeds the loading capacity of currently available d
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Ion slippage through Li+-centered G-quadruplex | Science Advances
Abstract Single-ion conductors have garnered attention in energy storage systems as a promising alternative to currently widespread electrolytes that allow migration of cations and anions. However, ion transport phenomena of most single-ion conductors are affected by strong ion (e.g., Li + )–ion (immobilized anionic domains) interactions and tortuous paths, which pose an obstacle to achieving per
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Uncovering the molecular mechanism for dual effect of ATP on phase separation in FUS solution | Science Advances
Abstract Recent studies reported that adenosine triphosphate (ATP) could inhibit and enhance the phase separation in prion-like proteins. The molecular mechanism underlying such a puzzling phenomenon remains elusive. Here, taking the fused in sarcoma (FUS) solution as an example, we comprehensively reveal the underlying mechanism by which ATP regulates phase separation by combining the semiempiri
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The lunar nodal cycle controls mangrove canopy cover on the Australian continent | Science Advances
Abstract Long-phase (interannual) tidal cycles have been shown to influence coastal flooding and sedimentation, but their role in shaping the extent and condition of tidal wetlands has received little attention. Here, we show that the 18.61-year lunar nodal cycle, popularly termed the "lunar wobble," is a dominant control over the expansion and contraction of mangrove canopy cover over much of th
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Identification of immunomodulatory drugs that inhibit multiple inflammasomes and impair SARS-CoV-2 infection | Science Advances
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces mild or asymptomatic COVID-19 in most cases, but some patients develop an excessive inflammatory process that can be fatal. As the NLRP3 inflammasome and additional inflammasomes are implicated in disease aggravation, drug repositioning to target inflammasomes emerges as a strategy to treat COVID-19. Here, we performed
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An AMPK phosphoregulated RhoGEF feedback loop tunes cortical flow–driven amoeboid migration in vivo | Science Advances
Abstract Development, morphogenesis, immune system function, and cancer metastasis rely on the ability of cells to move through diverse tissues. To dissect migratory cell behavior in vivo, we developed cell type–specific imaging and perturbation techniques for Drosophila primordial germ cells (PGCs). We find that PGCs use global, retrograde cortical actin flows for orientation and propulsion duri
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Ambush predation and the origin of euprimates | Science Advances
Abstract Primates of modern aspect (euprimates) are characterized by a suite of characteristics (e.g., convergent orbits, grasping hands and feet, reduced claws, and leaping), but the selective pressures responsible for the evolution of these euprimate characteristics have long remained controversial. Here, we used a molecular phyloecological approach to determine the diet of the common ancestor
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Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells | Science Advances
Abstract IFNα is a key regulator of the dialogue between pancreatic β cells and the immune system in early type 1 diabetes (T1D). IFNα up-regulates HLA class I expression in human β cells, fostering autoantigen presentation to the immune system. We observed by bulk and single-cell RNA sequencing that exposure of human induced pluripotent-derived islet-like cells to IFNα induces expression of HLA
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Global seaweed productivity | Science Advances
Abstract The magnitude and distribution of net primary production (NPP) in the coastal ocean remains poorly constrained, particularly for shallow marine vegetation. Here, using a compilation of in situ annual NPP measurements across >400 sites in 72 geographic ecoregions, we provide global predictions of the productivity of seaweed habitats, which form the largest vegetated coastal biome on the p
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Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction | Science Advances
Abstract The mechanism of action of eprenetapopt (APR-246, PRIMA-1 MET ) as an anticancer agent remains unresolved, although the clinical development of eprenetapopt focuses on its reported mechanism of action as a mutant-p53 reactivator. Using unbiased approaches, this study demonstrates that eprenetapopt depletes cellular antioxidant glutathione levels by increasing its turnover, triggering a n
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Environmental risks from artificial nighttime lighting widespread and increasing across Europe | Science Advances
Abstract The nighttime environment of much of Earth is being changed rapidly by the introduction of artificial lighting. While data on spatial and temporal variation in the intensity of artificial lighting have been available at a regional and global scale, data on variation in its spectral composition have only been collected for a few locations, preventing variation in associated environmental
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Air pollution may spur irregular heart rhythms in healthy teens
A first-of-its-kind study examining the impact of air pollution on healthy teenagers found that air pollution may trigger an irregular heart rhythm within two hours after exposure. Reducing the risk of irregular heart rhythms — known as arrhythmias — during adolescence may help reduce the risk of sudden cardiac death and developing heart disease in adulthood. Wearing face masks and avoiding vigo
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Harvard Professor Defends Claim That Alien Spacecraft Cruised Through Solar System
Harvard astronomer Avi Loeb has long suggested that there's a chance 'Oumuamua, a mysterious object that visited our solar system back in 2017, may have been an alien spacecraft that came by for a visit. In a 2021 paper , Loeb argued that 'Oumuamua could have been a probe sent by an extraterrestrial civilization, an explanation that has proven divisive among his peers . Most recently, an internat
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Zuckerberg-Hating Lunatic Sets Off Bomb at Northeastern University
Harrowing Last night, a bomb detonated at the virtual reality center of Boston's Northeastern University — and a note left with the device offers clues as to the perpetrator's unhinged motives. As CNN reports , a man who worked at Northeastern's virtual reality center was injured and is in the hospital after opening a case that housed the explosive, though university officials have stressed that
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Decoupled Asian monsoon intensity and precipitation during glacial-interglacial transitions on the Chinese Loess Plateau
Nature Communications, Published online: 14 September 2022; doi:10.1038/s41467-022-33105-2 In considering Asian monsoon intensity and precipitation during glacial-interglacial transitions in Chinese Loess Plateau, a new study finds that brGDGT-DLNN method can significantly extend the temporal scale record of the EASM and is not restricted by geographic location compared with stalagmite records.
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Energy comparison of sequential and integrated CO2 capture and electrochemical conversion
Nature Communications, Published online: 14 September 2022; doi:10.1038/s41467-022-33145-8 Coupling CO2 capture and electrolysis offers new opportunities to reduce energy cost. Here, the authors identify that the integrated electrolyser must show similar performance to the gas-fed electrolyser to ensure an energy benefit of up to 44% versus sequential capture and conversion processes.
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A More Complete Archive of the American South
One of the first photographs I fell in love with was Robert Frank's Fourth of July, Coney Island (1958). Night has fallen on Coney Island. The sky, which stretches across the top third of Frank's photograph , looks to be painted solid black. In the foreground, far from the crowds in the distance, lies a beautiful young Black man, his back to debris left in the sand. He lies alone, asleep, curled
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100 Years Ago in Photos: A Look Back at 1922
A century ago, the newly established Irish Free State was descending into civil war, Russia was still enduring a terrible famine, construction of the Lincoln Memorial was completed in Washington, D.C., Benito Mussolini's Fascist Party seized control of the Italian government, and much more. Please take a moment for a look back at some of the events and sights from around the world 100 years ago.
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Beyond sound: Red-eyed treefrogs use sound and vibration in calls for mates and aggression
One would be hard-pressed to take a walk outside without hearing the sounds of calling animals. During the day, birds chatter back and forth, and as night falls, frogs and insects call to defend territories and to attract potential mates. For several decades, biologists have studied these calls with great interest, taking away major lessons about the evolution of animal displays and the processes
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Beyond sound: Red-eyed treefrogs use sound and vibration in calls for mates and aggression
One would be hard-pressed to take a walk outside without hearing the sounds of calling animals. During the day, birds chatter back and forth, and as night falls, frogs and insects call to defend territories and to attract potential mates. For several decades, biologists have studied these calls with great interest, taking away major lessons about the evolution of animal displays and the processes
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Researchers develop a new way to predict droughts
Scientists looking at the meteorological impacts of climate change have typically looked at increases in severe weather and hurricanes. Now, they are studying another consequence of global warming that will have significant economic ramifications: drought.
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Technique developed in mice could aid detection of cancer in dense breasts
A two-pronged approach to imaging breast density in mice resulted in better detection of changes in breast tissue, including spotting early signs of cancer. The researchers hope that this approach will be translated from mice and improve breast imaging for people; it may also help with prognosis of disease as density can be linked to specific patterns of mammary gland growth, including signs of ca
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Using eyes in the sky to locate seals in a rapidly changing Arctic
This summer, researchers managed to collect stunning drone images of both ringed seals and walruses. In one fjord, the St. Jonsfjorden, twelve ringed seals were found spread out throughout the fjord, resting on the fast ice. However, approaching and identifying these individuals is very challenging. Since ringed seals are hunted by polar bears, any mammal—either walking on four or two legs—will be
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Single 'nanoconfined' molecules: Making and breaking of chemical bonds
Researchers around the world are working to develop efficient materials to convert CO2 into usable chemical substances — work that is particularly pressing in view of global warming. A team has discovered a new and promising approach: catalytically active molecules are nanoconfined — meaning they are put into an environment that leaves very little space for the single molecules — on a surface t
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Using eyes in the sky to locate seals in a rapidly changing Arctic
This summer, researchers managed to collect stunning drone images of both ringed seals and walruses. In one fjord, the St. Jonsfjorden, twelve ringed seals were found spread out throughout the fjord, resting on the fast ice. However, approaching and identifying these individuals is very challenging. Since ringed seals are hunted by polar bears, any mammal—either walking on four or two legs—will be
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Kebnekaise's southern peak once again lower than the northern peak
Since September 2019, Sweden has had a new official highest point. Researchers at Stockholm University's research station in Tarfala established that the southern peak of the Kebnekaise mountain, at 2095.6 meters, was now lower than the northern peak, with a height of 2096.8 meters. Scientists had long predicted that the south peak, consisting of a snow-covered glacier, would shrink due to the war
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Research finds educators need mental health support following hurricanes
After Hurricanes Harvey and Matthew hit Texas and North Carolina, it was the custodians who removed debris and damaged supplies from the athletic fields. It was the principals who stayed in the building for 24 hours while their schools operated as shelters. It was the teachers who ran to the local pharmacy to retrieve students' lifesaving medicine while communication was limited.
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The origin of life in an RNA pocket
This story begins several billion years ago. There's only chemistry, no biology—that is, plenty of chemical compounds exist on Earth, but life hasn't yet emerged. Then, among myriads of randomly self-assembled chemical structures, one tiny RNA molecular machine reveals itself as perfectly suitable for creating bonds between activated amino acids, the building blocks of future proteins.
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The origin of life in an RNA pocket
This story begins several billion years ago. There's only chemistry, no biology—that is, plenty of chemical compounds exist on Earth, but life hasn't yet emerged. Then, among myriads of randomly self-assembled chemical structures, one tiny RNA molecular machine reveals itself as perfectly suitable for creating bonds between activated amino acids, the building blocks of future proteins.
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Single 'nanoconfined' molecules: Making and breaking of chemical bonds
Researchers around the world are working to develop efficient materials to convert CO2 into usable chemical substances — work that is particularly pressing in view of global warming. A team has discovered a new and promising approach: catalytically active molecules are nanoconfined — meaning they are put into an environment that leaves very little space for the single molecules — on a surface t
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Precise control of catalytic reactions
A team develops a nanoreactor combining magnetic material and plasmonic catalysts. Remote control of step-by-step catalytic reactions of precursor led to cinnamaldehyde product with 95% yield.
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A switch telling the brain when to learn and when to remember
The memory system alternates between periods of learning and remembering. These two functions are controlled by different neural circuits. Using an animal model, scientists recently identified a neural signal in the hippocampus, a brain region essential for forming and recalling memories, that enables the brain to alternate between remembering and learning modes.
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Genetic discovery could lead to better treatments for common tumor in dogs
Newly discovered genetic commonalities and differences among the most prevalent types of canine soft tissue sarcomas, a common and potentially deadly tumor, could pave the way for more accurate diagnosis and better treatments in the future. Using next-generation sequencing techniques and computation approaches, a team of researchers and veterinarians examined the genetic makeup of the three most c
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Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli
Nature Communications, Published online: 14 September 2022; doi:10.1038/s41467-022-32831-x New cryo-EM structures of the formate hydrogenlyase complex from the model bacterium E. coli clarify how electrons and protons move through the complex and are combined to make H2 gas. The complex shows important similarities and differences to related bioenergetic complexes across the tree of life.
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They Put GPT-3 Into That Robot With Creepily Realistic Facial Expressions and Yikes
Welcome to Ameca UK-based robotics company Engineered Arts just gave its ultra realistic looking humanoid robot Ameca a voice — and she has a lot to say. In a new video , the company showed off Ameca having a conversation with a number of the company's engineers, courtesy of a speech synthesizer and OpenAI's GPT 3, cutting-edge language model that uses deep learning to generate impressively human
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NASA's Moon Spacecraft Is Tumbling Out of Control
Pop a Cap NASA's tiny, Moon-bound CAPSTONE probe is once again in trouble after its launch earlier this summer — and is now literally tumbling out of control. Statements issued this week by NASA and Advanced Space , the company managing the itty bitty cube-shaped satellite, admitted that an unknown issue caused CAPSTONE to tumble last week in what the contractor described as an "emergency." "The
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Above and belowground traits vary in response to soil moisture availability and plant competition
Functional traits have been used to explain plant responses to alterations in water availability. Our understanding of plant responses to biotic and abiotic drivers are largely based on aboveground plant traits. Due to the limited consideration of belowground plant traits, a general view of plant water use strategies remains elusive.
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Are we missing a crucial component of sea-level rise?
Across Antarctica, some parts of the base of the ice sheet are frozen, while others are thawed. Scientists show that if some currently frozen areas were also to thaw, it can increase ice loss from glaciers that are not currently major sea-level contributors.
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Tropical insects are extremely sensitive to changing climates
Insects that are adapted to perennially wet environments, like tropical rainforests, don't tend to do well when their surroundings dry out. New research indicates they may be equally averse to heavy rainfall. The results of an extensive five-year study conducted in Peru revealed a 50% decline in arthropod biomass following short periods of both drought and increased precipitation. One of only a fe
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Reviews show aesthetics matter for assistive devices
People often consider the look, texture, and, occasionally, the smell of two assistive devices—compression gloves and a knee brace—when reviewing the products online, a new study shows. The findings detail key aesthetic characteristics that users care about as well as the language they're using to describe them—factors that could be important for manufacturers to consider in product development.
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Increase in LED lighting 'risks harming human and animal health'
Transition to blue light radiation across Europe increases suppression of sleep hormone melatonin, say scientists Blue light from artificial sources is on the rise, which may have negative consequences for human health and the wider environment, according to a study. Academics at the University of Exeter have identified a shift in the kind of lighting technologies European countries are using at
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'Wobbly' moon probable cause of mass tree deaths in Australia, scientists say
Analysis of satellite imaging shows correlation between fluctuation in mangrove canopy cover and lunar nodal cycle Follow our Australia news live blog for the latest updates Get our free news app , morning email briefing or daily news podcast A wobble in the moon's orbit around Earth affects mangrove cover across Australia and likely contributed to mass tree deaths in the Gulf of Carpentaria, new
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What ancient dung reveals about Epipaleolithic animal tending
Tiny crystals in ancient animal dung serve as key evidence in a new analysis suggesting the possibility that hunter-gatherers at Abu Hureyra, Syria, may have tended small numbers of animals just outside their dwellings between 12,800 and 12,300 years ago. Alexia Smith of the University of Connecticut and colleagues present these findings in the open-access journal PLOS ONE on September 14, 2022.
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Modeling antimicrobial use and resistance in Canadian turkey flocks
Antimicrobial resistance in gut bacteria is constantly being detected on poultry farms and in poultry retail products worldwide, including in turkey flocks. Concerningly, surveillance information and studies on the associations between antimicrobial resistance and antimicrobial use in turkeys have been scarce during the last decade. In a new study, researchers across North America have modeled how
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Men are more likely than women to flirt at work for personal gain
Men are more likely than women to engage in social sexual behavior for personal gain, and it's most often men in lower-power positions who initiate it, researchers report. The new study finds evidence that it's actually men in subordinate positions who are most likely to flirt, use sexual innuendo, and even harass female bosses as a way to demonstrate their masculinity and power for personal gain
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Modeling antimicrobial use and resistance in Canadian turkey flocks
Antimicrobial resistance in gut bacteria is constantly being detected on poultry farms and in poultry retail products worldwide, including in turkey flocks. Concerningly, surveillance information and studies on the associations between antimicrobial resistance and antimicrobial use in turkeys have been scarce during the last decade. In a new study, researchers across North America have modeled how
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Study tracks waterbird use of Chicago-area wetlands
A three-year study in northeastern Illinois and northwestern Indiana found that—even at small scales—emergent wetlands or ponds support many wetland bird species. The study also found that, at least in the years surveyed, the level of urbanization had little effect on most of the studied species' use of such sites, provided the right kinds of habitat were available.
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New study cracks the code to increasing grain size and reducing chalkiness in rice
Improving the yield of rice grains and enhancing their appearance is a key standpoint for rice cultivation. Now, a group of researchers from China have identified a gene variant present in wild rice that controls the length, width, and chalkiness of rice grains. The introduction of this variant, called gl9, could help in the breeding of new rice varieties with high grain yields and a desirable app
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Italian Probe Will Watch as NASA Smashes Asteroid With Battering Ram
Guardians of the Galaxy Every hero needs a sidekick. Or, at the very least, a personal videographer. Case in point: NASA's asteroid-smashing Direct Asteroid Redirection Test (DART) spacecraft , slated to crash into the asteroid Dimorphos on September 26, is currently racing towards its target. But it's not alone! Space.com reports that trailing behind the doomed DART craft is a tiny Italian micro
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Study tracks waterbird use of Chicago-area wetlands
A three-year study in northeastern Illinois and northwestern Indiana found that—even at small scales—emergent wetlands or ponds support many wetland bird species. The study also found that, at least in the years surveyed, the level of urbanization had little effect on most of the studied species' use of such sites, provided the right kinds of habitat were available.
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New study cracks the code to increasing grain size and reducing chalkiness in rice
Improving the yield of rice grains and enhancing their appearance is a key standpoint for rice cultivation. Now, a group of researchers from China have identified a gene variant present in wild rice that controls the length, width, and chalkiness of rice grains. The introduction of this variant, called gl9, could help in the breeding of new rice varieties with high grain yields and a desirable app
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Chemical additives improve stability of high-density lithium-ion batteries
As our need for high-density batteries increases with widespread adoption of electric cars and alternative energy sources, improving the stability and capacity of lithium-ion batteries is a necessity. Current lithium-ion battery technology, which often uses nickel, is less stable at extreme temperatures, leading to overheating due to both temperature and high voltages. These batteries also tend to
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COVID was top cause of death for people with intellectual disabilities in 2020
In 2020, COVID was the leading cause of death for people with intellectual and developmental disabilities, researchers report. For a new study, the researchers looked at 2020 death certificate data to examine death patterns for people with or without an intellectual and developmental disability (IDD). They found that for those without an IDD, COVID was the third leading cause of death, following
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Microneedle tattoo technique could make tattooing painless and fast
Scientists at Georgia Tech say press-on innovation opens opportunities for medical and cosmetic use Painless, bloodless tattoos have been created by scientists, who say the technique could have medical and cosmetic applications. The technique, which can be self-administered, uses microneedles to imprint a design into the skin without causing pain or bleeding. Initial applications are likely to be
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How an extra-clock ultradian brain oscillator sustains circadian timekeeping
On September 2, Luo Dong-Gen and his research team from Peking University's School of Life Sciences, McGovern Institute for Brain Research, Center for Quantitative Biology, and Center for Life Sciences jointly published a research paper titled "An extra-clock ultradian brain oscillator sustains circadian timekeeping" in Science Advances.
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Enabling precise control of catalytic reactions
Various chemical reactions occur one after another in cells, and life is maintained as each step of the reaction is regulated without error. Recently, a Korean research team has developed a dual-catalyst system that can precisely control catalytic reactions much as cells can.
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How an extra-clock ultradian brain oscillator sustains circadian timekeeping
On September 2, Luo Dong-Gen and his research team from Peking University's School of Life Sciences, McGovern Institute for Brain Research, Center for Quantitative Biology, and Center for Life Sciences jointly published a research paper titled "An extra-clock ultradian brain oscillator sustains circadian timekeeping" in Science Advances.
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High-strength pultruded thermoplastic composites made of new raw material
Skoltech researchers have enhanced pultrusion—a technology used to produce fiber-reinforced polymers of constant cross-section—profiles. These are light and stiff composite materials made of plastic and glass or carbon fibers. They do not rust, can be welded, are suitable for recycling, and could someday replace steel and aluminum in civil engineering, marine construction, and elsewhere. For now,
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'Yes, but not like this!' Why urban densification often lacks public acceptance
Densifying existing settlements while containing urban sprawl—this idea has spread far beyond urban planning circles and is now recognized as a key principle of urban development. Ultimately, dense and compact cities can contribute to several environmental, economic, and social benefits: less urban sprawl, protection of undeveloped land, shorter transport routes, lower greenhouse gas emissions, th
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Researchers develop a reactor that can destroy 'forever chemicals'
"Forever chemicals," named for their ability to persist in water and soil, are a class of molecules that are ever-present in our daily lives, including food packaging and household cleaning products. Because these chemicals don't break down, they end up in our water and food, and they can lead to health effects, such as cancer or decreased fertility.
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New phases of water detected
Scientists at the University of Cambridge have discovered that water in a one-molecule layer acts like neither a liquid nor a solid, and that it becomes highly conductive at high pressures.
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Ag's challenging future in a changing climate
This is a re-post from Yale Climate Connections by Jeff Masters Increased drought and extreme heat adversely affecting agriculture likely pose the highest threat to civilization over the next 40 years. The greatest danger: extreme droughts supercharged by climate change, affecting multiple grain-growing areas simultaneously, causing "food shock" events that could trigger food prices spikes leadin
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Investigating better biotransformations
Research in the International Journal of Bioinformatics Research and Applications has investigated the chemistry and behavior of a useful natural product made by the Madagascar periwinkle (Catharanthus roseus Bunge). The work could expand the repertoire of a growing area of chemical science—biotransformation—wherein nature's molecular machinery is used to build and alter novel compounds in the lab
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Best Powered Speakers for Turntables in 2022
Powered speakers reduce two of the biggest barriers preventing people from setting up a turntable audio system: cost and space. This one component replicates the functionality of a pair of passive speakers and a stereo receiver. You can plug your turntable directly into a pair of active speakers, hit the power button on both, and drop your needle. Using powered speakers with a turntable also elim
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Google and Oxford Scientists Publish Paper Claiming AI Will "Likely" Annihilate Humankind
Existential Threat Researchers at Google Deepmind and the University of Oxford have concluded that it's now "likely" that superintelligent AI will spell the end of humanity — a grim scenario that more and more researchers are starting to predict . In a recent paper published in the journal AI Magazine , the team — comprised of DeepMind senior scientist Marcus Hutter and Oxford researchers Michael
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Investigating better biotransformations
Research in the International Journal of Bioinformatics Research and Applications has investigated the chemistry and behavior of a useful natural product made by the Madagascar periwinkle (Catharanthus roseus Bunge). The work could expand the repertoire of a growing area of chemical science—biotransformation—wherein nature's molecular machinery is used to build and alter novel compounds in the lab
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Flying to (hypothetical) Planet 9: Why visit it, how could we get there and would it surprise us like Pluto?
In a recent study submitted to Earth and Planetary Astrophysics, an international team of researchers discuss the various mission design options for reaching a hypothetical Planet 9, also known as "Planet X," which state-of-the-art models currently estimate to possess a semi-major axis of approximately 400 astronomical units (AU). The researchers postulate that sending a spacecraft to Planet 9 cou
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On its hunt for dark energy, a telescope stopped to look at the Lobster Nebula
If you thought dark matter was difficult to study, studying dark energy is even more challenging. Dark energy is perhaps the most subtle phenomenon in the universe. It drives the evolution of the cosmos, but its effects are only seen on intergalactic scales. So to study dark energy in detail, you need a great deal of observations of wide areas of the sky.
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Ghana's efforts to employ young people and regrow forests could work better
Deforestation has been an issue of global concern for many years. Deforestation is a major environmental concern because of its adverse effects on ecological sustainability, agricultural productivity and overall quality of life of the people. As populations increase, there is a higher demand for both forest products and forest lands for development activities. The Food and Agricultural Organizatio
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It's a planet: New evidence of baby planet in the making
Astronomers agree that planets are born in protoplanetary disks—rings of dust and gas that surround young, newborn stars. While hundreds of these disks have been spotted throughout the universe, observations of actual planetary birth and formation have proved difficult within these environments.
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African crops provide a nutrient-dense, gluten-free solution
The world is producing more food than ever before, yet millions of Africans still lack proper nutrition. Focusing on the potential of African crops to help combat malnutrition on the African continent, the EU-funded InnoFoodAfrica project has now turned its attention to gluten-free products.
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Student discovers a group of galaxies clustered together in the early universe
While developing and testing astronomical software on existing data, a master's student in astronomy fortuitously discovered a group of galaxies in the very early universe. In addition to demonstrating the potential of the software, the finding provides insight into the assembly of massive structures, as well as how some galaxies cease to form stars.
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What lies beneath melting glaciers and thawing permafrost?
Around the planet, ice is rapidly disappearing. From mountain tops, the poles, the seas, and the tundra. As the ice melts, it's exposing new surfaces, new opportunities, and new threats—including valuable mineral deposits, archaeological relics, novel viruses, and more.
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What best predicts violence in Richmond neighborhoods? Negligent landlords
Negligent landlords—those who allow their properties to become dilapidated despite having tenants—are a significant predictor of violence in Richmond neighborhoods, even more than personal property tax delinquency, population density, income levels and other factors, according to a new study by researchers at Virginia Commonwealth University.
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Evolution and ecological competition of multicellular life cycles
New studies by the Max Planck Institute for Evolutionary Biology show that competition between different evolutionary developmental stages of multicellular life cycles can be important for the development of an entire population. Without direct competition, only the growth rate of a population determines which life cycle prevails.
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A thermal management material that responds to heat or cold by folding or unfolding without need for a power source
A team of researchers at Nankai University has developed a thermal management multi-layer material that responds to heat or cold by folding or unfolding itself without the need for an external power source. In their paper published in Proceedings of the National Academy of Sciences, the group describes how they came to develop the material and detail its performance when tested.
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Should crowdfunding be this complicated?
In 2015, John Donovan was listening to a podcast when he learned about an entrepreneur who was hoping to start a business in the podcast space. Given the topic and audience, it would seem this entrepreneur could easily reach a large number of potential investors. However, U.S. regulations at the time prevented businesses from raising capital from non-accredited investors, i.e., individuals who are
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Dense and permeable: Molecular organization of tight junctions decoded
They seal epithelial cells and, under certain conditions, allow the passage of ions and water: Tight junctions form a paracellular barrier in tissues and their dysfunction is associated with diseases. Although their molecular components have been known since the 1990s, it is not apparent how the 26 proteins called claudins are organized.
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Young genes found to adapt faster than old ones
A new study from the Max Planck Institute for Evolutionary Biology in Plön and the University of Sussex in the UK shows that the age of a gene determines how fast they adapt. These findings demonstrate how gene evolution occurs as an "adaptive walk" through time.
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Comparing effectiveness of camouflage in different animals
A quartet of researchers from Universidade Estadual de Campinas, Básicas, Universidade de São Paulo, and São Bernardo do Campo, all in Brazil, has conducted a study of the effectiveness of different types of camouflage strategies in animals. In their paper published in Proceedings of the Royal Society B: Biological Sciences, João Vitor de Alcantara Viana, Camila Vieira, Rafael Campos Duarte and Gu
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Scientist discovers new oxidation state of rhodium
Mayara da Silva Santos, doctoral candidate at the University of Freiburg's Institute of Physics, has discovered a new oxidation state of rhodium. This chemical element is one of the most catalytically important platinum-group metals and is used, for example, in catalytic converters for automobiles.
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Soybean virus may give plant-munching bugs a boost in survival
Most viral infections negatively affect an organism's health, but one plant virus in particular—soybean vein necrosis orthotospovirus, often referred to as SVNV—may actually benefit a type of insect that commonly feeds on soybean plants and can transmit the virus to the plant, causing disease, according to Penn State research.
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There's no Tiananmen Square in the new Chinese image-making AI
There's a new text-to-image AI in town. With ERNIE-ViLG, a new AI developed by the Chinese tech company Baidu, you can generate images that capture the cultural specificity of China. It also makes better anime art than DALL-E 2 or other Western image-making AIs. But there are many things—like Tiananmen Square, the country's second-largest city square and a symbolic political center—that the AI re
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These tiny coral reef fish parents decide when their embryos hatch
Scientists report a documented case of a coral reef fish directly regulating when its offspring hatch. Male neon gobies hatch their embryos by removing eggs from the nest with their mouth, transporting the newly-hatched larvae to the opening of the sponge where they live — and then spitting them out of the sponge entrance. This provides evidence that, just like humans, fish parents can make adapt
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Former SpaceX Guy Aims to Launch Giant Mirrors Into Orbit to Shine on Solar Panels at Night
Night Light Ben Nowack, a 26-year-old inventor and former SpaceX employee, wants to send satellites with mirrors mounted on them into orbit to allow us to generate solar energy at night, Vice reports . "Everybody's installing so many solar panels everywhere," Nowack told the site. "It's really a great candidate to power humanity." "But sunlight turns off, it's called nighttime," he added. "If you
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Control of cell state transitions
Nature, Published online: 14 September 2022; doi:10.1038/s41586-022-05194-y An approach called cell state transition assessment and regulation uses diverse multiomics data to map cell states, model their transitions, and understand the signalling networks that control them.
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A universal coupling mechanism of respiratory complex I
Nature, Published online: 14 September 2022; doi:10.1038/s41586-022-05199-7 Cryo-electron microscopy studies of Escherichia coli complex I suggest a conserved mechanism of coupled proton transfers and electrostatic interactions that result in proton ejection from the complex exclusively at the distal NuoL subunit.
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Discovery of charge density wave in a kagome lattice antiferromagnet
Nature, Published online: 14 September 2022; doi:10.1038/s41586-022-05034-z Analysis of the antiferromagnetic ordered phase of kagome lattice FeGe suggests that charge density wave is the result of a combination of electronic-correlations-driven antiferromagnetic order and instability driven by van Hove singularities.
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CDK11 regulates pre-mRNA splicing by phosphorylation of SF3B1
Nature, Published online: 14 September 2022; doi:10.1038/s41586-022-05204-z CDK11 associates with SF3B1 and phosphorylates threonine residues at the N terminus of SF3B1 during spliceosome activation, and the inhibition of CDK11 blocks the activation and leads to widespread intron retention and the accumulation of non-functional spliceosomes on pre-mRNAs and chromatin.
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Living material assembly of bacteriogenic protocells
Nature, Published online: 14 September 2022; doi:10.1038/s41586-022-05223-w A bacteriogenic strategy for constructing membrane-bounded, molecularly crowded, and compositionally, structurally and morphologically complex synthetic cells provides opportunities for the fabrication of new synthetic cell modules and augmented living/synthetic cell constructs.
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Delayed fluorescence from inverted singlet and triplet excited states
Nature, Published online: 14 September 2022; doi:10.1038/s41586-022-05132-y A fluorescent molecule is described that does not follow Hund's rule and instead shows singlet and triplet excited states with inverted energy levels, leading to high-efficiency OLEDs with potential implications for optoelectronic devices.
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Columnar structure of human telomeric chromatin
Nature, Published online: 14 September 2022; doi:10.1038/s41586-022-05236-5 Cryogenic electron microscopy analyses reveal a new, compact structure of telomeric chromatin, providing mechanistic insight into telomere maintenance and function.
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Rapid shifting of a deep magmatic source at Fagradalsfjall volcano, Iceland
Nature, Published online: 14 September 2022; doi:10.1038/s41586-022-04981-x Primitive lavas of the Fagradalsfjall eruption present a window into the deep roots of a magmatic system previously inaccessible to near-real-time investigation, showing that eruptible batches of basaltic magma mix on a timescale of weeks.
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Extended Bose–Hubbard model with dipolar excitons
Nature, Published online: 14 September 2022; doi:10.1038/s41586-022-05123-z Confining semiconductor dipolar excitons using an artificial two-dimensional square lattice emulates extended Bose–Hubbard Hamiltonians, thus enabling control of boson-like arrays in lattices with programmable geometries and more than 100 sites.
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Two-drug trick to target the brain blocks toxicity in the body
Nature, Published online: 14 September 2022; doi:10.1038/d41586-022-02892-5 When combined, two drugs alter the activity of a protein complex called target of rapamycin complex 1 such that it is inhibited in the brain but not the body, enabling the treatment of brain tumours in mice without systemic toxicity.
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A glimpse into the deepest parts of the Fagradalsfjall volcanic system
Nature, Published online: 14 September 2022; doi:10.1038/d41586-022-02179-9 After around 780 years without volcanic activity, Iceland's Reykjanes peninsula sprang to life in 2021, when magma breached the surface at the Fagradalsfjall volcano. Observed changes in the lava composition have provided an unprecedented record of the supply and mixing mechanics of deep magma at the base of the crust.
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Simple solids can mimic complex electronic states
Nature, Published online: 14 September 2022; doi:10.1038/d41586-022-02889-0 Solid-state systems that are designed to simulate the quantum behaviour of electrons in a solid could rival established techniques that require exhaustive computation or precise control of atoms in dilute gases.
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Life brought to artificial cells
Nature, Published online: 14 September 2022; doi:10.1038/d41586-022-02231-8 Can artificial cells be built from basic components? Systems that have complex architectures and functions evocative of natural cells have been prepared by recycling the contents of bacterial cells in synthetic droplets.
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Team finds oldest ever gibbon fossil
Scientists have discovered the earliest gibbon fossil. The finding helps fill a long-elusive evolutionary gap in the history of apes. The work, which appears in the Journal of Human Evolution , centers on hylobatids, a family of apes that includes 20 species of living gibbons. Gibbons are found throughout tropical Asia from northeastern India to Indonesia. "Hylobatids fossil remains are very rare
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A Swedish Company Wants to Transform Offshore Wind With Vertical-Axis Turbines
Even as more offshore wind projects launch and the turbines they use get bigger, there are questions around offshore wind's economic viability . Unsurprisingly, hauling huge equipment with multiple moving parts out to deep, windy sections of ocean, setting them up, and building lines to transmit the electricity they generate back to land is expensive. Really expensive. In our profit-driven capita
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